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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs11030104
log Bayes Factor = 0.898447
Chromosome 11   position 27,684,517  (GRCh37) Explore rs11030104 on Ensembl!
Variant rs11030104 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
H73.8 Other specified disorders of tympanic membrane
0.000 0.468 0.532
H73 Other disorders of tympanic membrane
0.000 0.472 0.528
H65-H75 Diseases of middle ear and mastoid
0.000 0.474 0.526
H65 Nonsuppurative otitis media
0.000 0.475 0.525
H71 Cholesteatoma of middle ear
0.000 0.477 0.523
E11.3 With ophthalmic complications
0.000 0.483 0.517
E11 Non-insulin-dependent diabetes mellitus
0.000 0.483 0.517
H65.3 Chronic mucoid otitis media
0.000 0.486 0.514
E11.2 With renal complications
0.000 0.489 0.511
E10-E14 Diabetes mellitus
0.000 0.527 0.473
H65.4 Other chronic nonsuppurative otitis media
0.000 0.527 0.473
E14.3 With ophthalmic complications
0.000 0.539 0.461
E14 Unspecified diabetes mellitus
0.000 0.541 0.459
E11.1 With ketoacidosis
0.000 0.542 0.458
H73.9 Disorder of tympanic membrane, unspecified
0.000 0.587 0.413
E11.6 With other specified complications
0.000 0.591 0.409
H65.2 Chronic serous otitis media
0.000 0.592 0.408
E11.5 With peripheral circulatory complications
0.000 0.597 0.403
H69 Other disorders of Eustachian tube
0.000 0.598 0.402
H36.0 Diabetic retinopathy
0.000 0.601 0.399
H70 Mastoiditis and related conditions
0.000 0.609 0.391
E11.8 With unspecified complications
0.000 0.612 0.388
H65.9 Nonsuppurative otitis media, unspecified
0.000 0.613 0.387
H73.0 Acute myringitis
0.000 0.621 0.378
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.000 0.623 0.377
H67 Otitis media in diseases classified elsewhere
0.000 0.623 0.377
H65.1 Other acute nonsuppurative otitis media
0.000 0.623 0.377
H65.0 Acute serous otitis media
0.000 0.623 0.377
E11.7 With multiple complications
0.000 0.629 0.371
E10 Insulin-dependent diabetes mellitus
0.000 0.632 0.368
E12 Malnutrition-related diabetes mellitus
0.000 0.660 0.339
H73.1 Chronic myringitis
0.000 0.665 0.335
E14.7 With multiple complications
0.000 0.670 0.329
E14.6 With other specified complications
0.000 0.670 0.329
E14.5 With peripheral circulatory complications
0.000 0.670 0.329
E14.2 Withrenal complications
0.000 0.670 0.329
E14.0 With coma
0.000 0.670 0.329
E10.3 With ophthalmic complications
0.000 0.670 0.330
H68 Eustachian salpingitis and obstruction
0.000 0.671 0.329
E14.1 With ketoacidosis
0.000 0.671 0.329
E11.0 With coma
0.000 0.674 0.326
E14.8 With unspecified complications
0.000 0.679 0.321
E10.2 With renal complications
0.000 0.684 0.316
E13 Other specified diabetes mellitus
0.000 0.685 0.315
H74 Other disorders of middle ear and mastoid
0.000 0.694 0.306
H69.8 Other specified disorders of Eustachian tube
0.000 0.697 0.303
H70.9 Mastoiditis, unspecified
0.000 0.698 0.302
H69.9 Eustachian tube disorder, unspecified
0.000 0.700 0.300
E11.4 With neurological complications
0.000 0.707 0.293
H69.0 Patulous Eustachian tube
0.000 0.711 0.288
H36 Retinal disorders in diseases classified elsewhere
0.000 0.713 0.287
E14.4 With neurological complications
0.000 0.714 0.286
H70.1 Chronic mastoiditis
0.000 0.715 0.285
E10.5 With peripheral circulatory complications
0.000 0.716 0.284
H70.2 Petrositis
0.000 0.719 0.281
H70.0 Acute mastoiditis
0.000 0.719 0.281
E10.8 With unspecified complications
0.000 0.725 0.275
E10.0 With coma
0.000 0.727 0.273
H67.8 Otitis media in other diseases classified elsewhere
0.000 0.729 0.271
H67.1 Otitis media in viral diseases classified elsewhere
0.000 0.729 0.271
H67.0 Otitis media in bacterial diseases classified elsewhere
0.000 0.729 0.271
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere
0.000 0.729 0.271
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere
0.000 0.729 0.271
H70.8 Other mastoiditis and related conditions
0.000 0.733 0.267
E10.7 With multiple complications
0.000 0.736 0.264
H66 Suppurative and unspecified otitis media
0.000 0.753 0.247
E12.9 Without complications
0.000 0.756 0.243
E12.8 With unspecified complications
0.000 0.756 0.243
E12.7 With multiple complications
0.000 0.756 0.243
E12.6 With other specified complications
0.000 0.756 0.243
E12.5 With peripheral circulatory complications
0.000 0.756 0.243
E12.4 With neurological complications
0.000 0.756 0.243
E12.3 With ophthalmic complications
0.000 0.756 0.243
E12.2 With renal complications
0.000 0.756 0.243
E12.1 With ketoacidosis
0.000 0.756 0.243
E12.0 With coma
0.000 0.756 0.243
H74.2 Discontinuity and dislocation of ear ossicles
0.000 0.758 0.242
E10.6 With other specified complications
0.000 0.759 0.241
E10.9 Without complications
0.000 0.762 0.238
H68.0 Eustachian salpingitis
0.000 0.764 0.236
E10.4 With neurological complications
0.000 0.765 0.235
H74.0 Tympanosclerosis
0.000 0.769 0.231
E13.8 With unspecified complications
0.000 0.774 0.226
E13.7 With multiple complications
0.000 0.774 0.226
E13.6 With other specified complications
0.000 0.774 0.226
E13.5 With peripheral circulatory complications
0.000 0.774 0.226
E13.4 With neurological complications
0.000 0.774 0.226
E13.3 With ophthalmic complications
0.000 0.774 0.226
E13.2 With renal complications
0.000 0.774 0.226
E13.1 With ketoacidosis
0.000 0.774 0.226
E13.0 With coma
0.000 0.774 0.226
H74.9 Disorder of middle ear and mastoid, unspecified
0.000 0.781 0.219
H30-H36 Disorders of choroid and retina
0.000 0.793 0.207
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.794 0.206
H72 Perforation of tympanic membrane
0.000 0.795 0.205
E13.9 Without complications
0.000 0.799 0.201
H74.3 Other acquired abnormalities of ear ossicles
0.000 0.801 0.199
H74.1 Adhesive middle ear disease
0.000 0.802 0.198
H74.8 Other specified disorders of middle ear and mastoid
0.000 0.802 0.198
H34 Retinal vascular occlusions
0.000 0.810 0.190
H68.1 Obstruction of Eustachian tube
0.001 0.812 0.188
H66.2 Chronic atticoantral suppurative otitis media
0.000 0.818 0.182
H31 Other disorders of choroid
0.000 0.821 0.179
H74.4 Polyp of middle ear
0.000 0.821 0.178
H66.3 Other chronic suppurative otitis media
0.000 0.822 0.178
H34.2 Other retinal artery occlusions
0.000 0.823 0.177
H66.1 Chronic tubotympanic suppurative otitis media
0.000 0.827 0.173
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.827 0.173
H72.1 Attic perforation of tympanic membrane
0.000 0.834 0.166
E65-E68 Obesity and other hyperalimentation
0.000 0.834 0.166
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.836 0.164
H35 Other retinal disorders
0.000 0.836 0.164
E05.9 Thyrotoxicosis, unspecified
0.000 0.836 0.164
E00-E07 Disorders of thyroid gland
0.000 0.838 0.162
H66.0 Acute suppurative otitis media
0.000 0.838 0.161
E66 Obesity
0.000 0.839 0.161
H31.0 Chorioretinal scars
0.000 0.842 0.158
E14.9 Without complications
0.000 0.844 0.156
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.844 0.156
H34.8 Other retinal vascular occlusions
0.000 0.846 0.154
E66.9 Obesity, unspecified
0.000 0.847 0.153
H30 Chorioretinal inflammation
0.000 0.849 0.150
H35.7 Separation of retinal layers
0.000 0.851 0.149
H66.9 Otitis media, unspecified
0.000 0.851 0.148
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.852 0.148
H35.8 Other specified retinal disorders
0.000 0.852 0.148
E66.8 Other obesity
0.000 0.855 0.145
E06 Thyroiditis
0.000 0.859 0.141
H31.1 Choroidal degeneration
0.000 0.861 0.139
H34.0 Transient retinal artery occlusion
0.000 0.864 0.136
H72.2 Other marginal perforations of tympanic membrane
0.000 0.867 0.133
E06.3 Autoimmune thyroiditis
0.000 0.869 0.131
H31.8 Other specified disorders of choroid
0.000 0.869 0.131
H66.4 Suppurative otitis media, unspecified
0.000 0.871 0.129
H31.9 Disorder of choroid, unspecified
0.000 0.872 0.128
H31.4 Choroidal detachment
0.000 0.872 0.128
H31.2 Hereditary choroidal dystrophy
0.000 0.872 0.128
H34.1 Central retinal artery occlusion
0.000 0.872 0.128
H35.2 Other proliferative retinopathy
0.000 0.875 0.125
E65 Localised adiposity
0.000 0.875 0.124
H34.9 Retinal vascular occlusion, unspecified
0.000 0.876 0.123
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.877 0.123
H30.9 Chorioretinal inflammation, unspecified
0.000 0.878 0.122
E67 Other hyperalimentation
0.000 0.881 0.119
E68 Sequelae of hyperalimentation
0.000 0.881 0.119
E05.5 Thyroid crisis or storm
0.000 0.882 0.118
E05.4 Thyrotoxicosis factitia
0.000 0.882 0.118
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.882 0.118
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.882 0.118
H35.1 Retinopathy of prematurity
0.000 0.882 0.118
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.884 0.116
E00 Congenital iodine-deficiency syndrome
0.000 0.884 0.116
E40-E46 Malnutrition
0.000 0.884 0.116
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.884 0.116
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.884 0.116
E66.1 Drug-induced obesity
0.000 0.884 0.116
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.885 0.115
H72.9 Perforation of tympanic membrane, unspecified
0.000 0.887 0.113
H31.3 Choroidal haemorrhage and rupture
0.000 0.887 0.113
E11.9 Without complications
0.000 0.888 0.112
H35.0 Background retinopathy and retinal vascular changes
0.000 0.888 0.112
H35.4 Peripheral retinal degeneration
0.000 0.890 0.110
H35.5 Hereditary retinal dystrophy
0.000 0.890 0.109
H30.8 Other chorioretinal inflammations
0.000 0.892 0.108
H30.1 Disseminated chorioretinal inflammation
0.000 0.892 0.108
H30.0 Focal chorioretinal inflammation
0.000 0.892 0.108
H72.8 Other perforations of tympanic membrane
0.000 0.893 0.107
H32.8 Other chorioretinal disorders in diseases classified elsewhere
0.000 0.893 0.106
H32.0 Chorioretinal inflammation in infectious and parasitic diseases classified elsewhere
0.000 0.893 0.106
H72.0 Central perforation of tympanic membrane
0.000 0.898 0.101
E06.5 Other chronic thyroiditis
0.000 0.898 0.101
E06.4 Drug-induced thyroiditis
0.000 0.898 0.101
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.898 0.101
E06.1 Subacute thyroiditis
0.000 0.898 0.101
E06.0 Acute thyroiditis
0.000 0.898 0.101
E05.8 Other thyrotoxicosis
0.000 0.901 0.098
H35.6 Retinal haemorrhage
0.000 0.905 0.095
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.906 0.094
H30.2 Posterior cyclitis
0.000 0.909 0.090
H35.9 Retinal disorder, unspecified
0.000 0.912 0.088
E67.8 Other specified hyperalimentation
0.000 0.914 0.086
E67.3 Hypervitaminosis D
0.000 0.914 0.086
E67.2 Megavitamin-B6 syndrome
0.000 0.914 0.086
E67.1 Hypercarotenaemia
0.000 0.914 0.086
E67.0 Hypervitaminosis A
0.000 0.914 0.086
E66.0 Obesity due to excess calories
0.000 0.914 0.085
H35.3 Degeneration of macula and posterior pole
0.000 0.916 0.084
E06.9 Thyroiditis, unspecified
0.000 0.916 0.084
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.916 0.084
E45 Retarded development following protein-energy malnutrition
0.000 0.916 0.084
E43 Unspecified severe protein-energy malnutrition
0.000 0.916 0.084
E42 Marasmic kwashiorkor
0.000 0.916 0.084
E41 Nutritional marasmus
0.000 0.916 0.084
E40 Kwashiorkor
0.000 0.916 0.084
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.916 0.083
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.916 0.083
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.916 0.083
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.916 0.083
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.916 0.083
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.916 0.083
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.916 0.083
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.916 0.083
E15 Nondiabetic hypoglycaemic coma
0.000 0.917 0.083
E03 Other hypothyroidism
0.000 0.921 0.079
E07 Other disorders of thyroid
0.000 0.922 0.078
E46 Unspecified protein-energy malnutrition
0.000 0.924 0.076
E16 Other disorders of pancreatic internal secretion
0.000 0.925 0.075
E50-E64 Other nutritional deficiencies
0.000 0.934 0.066
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.934 0.066
E03.8 Other specified hypothyroidism
0.000 0.936 0.064
E44.1 Mild protein-energy malnutrition
0.000 0.940 0.060
E44.0 Moderate protein-energy malnutrition
0.000 0.940 0.060
E03.5 Myxoedema coma
0.000 0.943 0.057
E03.4 Atrophy of thyroid (acquired)
0.000 0.943 0.057
E03.3 Postinfectious hypothyroidism
0.000 0.943 0.057
E03.1 Congenital hypothyroidism without goitre
0.000 0.943 0.057
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.943 0.057
E07.8 Other specified disorders of thyroid
0.000 0.944 0.056
E07.1 Dyshormogenetic goitre
0.000 0.944 0.056
E07.0 Hypersecretion of calcitonin
0.000 0.944 0.056
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.946 0.054
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.946 0.054
E16.4 Abnormal secretion of gastrin
0.000 0.946 0.054
E16.3 Increased secretion of glucagon
0.000 0.946 0.054
E10.1 With ketoacidosis
0.004 0.950 0.046
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.952 0.047
E63 Other nutritional deficiencies
0.000 0.952 0.047
E56 Other vitamin deficiencies
0.000 0.952 0.047
E51 Thiamine deficiency
0.000 0.952 0.047
E50 Vitamin A deficiency
0.000 0.952 0.047
E60 Dietary zinc deficiency
0.000 0.952 0.047
E59 Dietary selenium deficiency
0.000 0.952 0.047
E58 Dietary calcium deficiency
0.000 0.952 0.047
E54 Ascorbic acid deficiency
0.000 0.952 0.047
E52 Niacin deficiency [pellagra]
0.000 0.952 0.047
H33 Retinal detachments and breaks
0.000 0.953 0.047
E16.1 Other hypoglycaemia
0.000 0.955 0.045
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.956 0.044
E61 Deficiency of other nutrient elements
0.000 0.956 0.044
K62.1 Rectal polyp
0.000 0.962 0.038
H33.0 Retinal detachment with retinal break
0.000 0.963 0.037
E50.9 Vitamin A deficiency, unspecified
0.000 0.965 0.034
E50.8 Other manifestations of vitamin A deficiency
0.000 0.965 0.034
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.965 0.034
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.965 0.034
E50.5 Vitamin A deficiency with night blindness
0.000 0.965 0.034
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.965 0.034
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.965 0.034
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.965 0.034
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.965 0.034
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.965 0.034
E51.9 Thiamine deficiency, unspecified
0.000 0.965 0.034
E51.8 Other manifestations of thiamine deficiency
0.000 0.965 0.034
E51.2 Wernicke's encephalopathy
0.000 0.965 0.034
E51.1 Beriberi
0.000 0.965 0.034
E56.9 Vitamin deficiency, unspecified
0.000 0.965 0.034
E56.8 Deficiency of other vitamins
0.000 0.965 0.034
E56.1 Deficiency of vitamin K
0.000 0.965 0.034
E56.0 Deficiency of vitamin E
0.000 0.965 0.034
E63.9 Nutritional deficiency, unspecified
0.000 0.965 0.034
E63.8 Other specified nutritional deficiencies
0.000 0.965 0.034
E63.1 Imbalance of constituents of food intake
0.000 0.965 0.034
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.965 0.034
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.965 0.034
E64.8 Sequelae of other nutritional deficiencies
0.000 0.965 0.034
E64.3 Sequelae of rickets
0.000 0.965 0.034
E64.2 Sequelae of vitamin C deficiency
0.000 0.965 0.034
E64.1 Sequelae of vitamin A deficiency
0.000 0.965 0.034
E64.0 Sequelae of protein-energy malnutrition
0.000 0.965 0.034
H33.4 Traction detachment of retina
0.000 0.966 0.034
E61.2 Magnesium deficiency
0.000 0.966 0.033
E53 Deficiency of other B group vitamins
0.000 0.967 0.033
E16.2 Hypoglycaemia, unspecified
0.000 0.968 0.032
E61.9 Deficiency of nutrient element, unspecified
0.000 0.968 0.031
E61.8 Deficiency of other specified nutrient elements
0.000 0.968 0.031
E61.7 Deficiency of multiple nutrient elements
0.000 0.968 0.031
E61.6 Vanadium deficiency
0.000 0.968 0.031
E61.5 Molybdenum deficiency
0.000 0.968 0.031
E61.4 Chromium deficiency
0.000 0.968 0.031
E61.3 Manganese deficiency
0.000 0.968 0.031
E61.0 Copper deficiency
0.000 0.968 0.031
E55 Vitamin D deficiency
0.001 0.969 0.030
E04 Other non-toxic goitre
0.000 0.969 0.031
I83 Varicose veins of lower extremities
0.000 0.970 0.030
H33.5 Other retinal detachments
0.000 0.972 0.028
H33.2 Serous retinal detachment
0.000 0.972 0.028
H33.1 Retinoschisis and retinal cysts
0.000 0.973 0.027
E53.9 Vitamin B deficiency, unspecified
0.000 0.974 0.026
E04.0 Non-toxic diffuse goitre
0.000 0.975 0.025
E61.1 Iron deficiency
0.000 0.976 0.024
E53.1 Pyridoxine deficiency
0.000 0.976 0.024
E53.0 Riboflavin deficiency
0.000 0.976 0.024
E03.9 Hypothyroidism, unspecified
0.000 0.976 0.024
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.024 0.976 0.000
E55.0 Rickets, active
0.001 0.978 0.022
E04.8 Other specified non-toxic goitre
0.000 0.978 0.022
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.978 0.022
T85.4 Mechanical complication of breast prosthesis and implant
0.022 0.978 0.000
Chapter VIII Diseases of the ear and mastoid process
0.000 0.978 0.022
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.021 0.979 0.000
I83.1 Varicose veins of lower extremities with inflammation
0.000 0.980 0.020
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
0.019 0.981 0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
0.019 0.981 0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.019 0.981 0.000
E07.9 Disorder of thyroid, unspecified
0.001 0.983 0.016
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium
0.016 0.984 0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium
0.016 0.984 0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.000 0.986 0.014
E04.9 Non-toxic goitre, unspecified
0.000 0.986 0.014
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
0.013 0.987 0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium
0.013 0.987 0.000
I51.8 Other ill-defined heart diseases
0.000 0.989 0.011
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
0.010 0.989 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.000 0.990 0.010
O94-O99 Other obstetric conditions, not elsewhere classified
0.009 0.991 0.000
H90-H95 Other disorders of ear
0.000 0.992 0.008
F43.1 Posttraumatic stress disorder
0.008 0.992 0.000
F43.0 Acute stress reaction
0.008 0.992 0.000
L90.0 Lichen sclerosus et atrophicus
0.000 0.993 0.007
G50.0 Trigeminal neuralgia
0.007 0.993 0.000
F43 Reaction to severe stress, and adjustment disorders
0.007 0.993 0.000
E04.2 Non-toxic multinodular goitre
0.000 0.993 0.007
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.007 0.993 0.000
I51 Complications and ill-defined descriptions of heart disease
0.000 0.993 0.007
I51.9 Heart disease, unspecified
0.000 0.993 0.007
H92 Otalgia and effusion of ear
0.000 0.993 0.007
O97 Death from sequelae of direct obstetric causes
0.007 0.993 0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery
0.007 0.993 0.000
O95 Obstetric death of unspecified cause
0.007 0.993 0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium
0.007 0.993 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.000 0.994 0.006
H92.1 Otorrhoea
0.000 0.994 0.006
H94 Other disorders of ear in diseases classified elsewhere
0.000 0.994 0.006
H60-H62 Diseases of external ear
0.000 0.994 0.005
O98.3 Other infections with a predominantly sexual mode of transmission complicating pregnancy, childbirth and the puerperium
0.005 0.994 0.000
I51.0 Cardiac septal defect, acquired
0.000 0.994 0.006
F43.2 Adjustment disorders
0.006 0.994 0.000
I51.6 Cardiovascular disease, unspecified
0.000 0.994 0.005
E55.9 Vitamin D deficiency, unspecified
0.001 0.995 0.004
F43.9 Reaction to severe stress, unspecified
0.005 0.995 0.000
F43.8 Other reactions to severe stress
0.005 0.995 0.000
I51.4 Myocarditis, unspecified
0.000 0.995 0.005
O98.9 Unspecified maternal infectious or parasitic disease complicating pregnancy, childbirth and the puerperium
0.005 0.995 0.000
O98.7 Human immunodeficiency [HIV] disease complicating pregnancy, childbirth and the puerperium
0.005 0.995 0.000
O98.6 Protozoal diseases complicating pregnancy, childbirth and the puerperium
0.005 0.995 0.000
O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium
0.005 0.995 0.000
O98.4 Viral hepatitis complicating pregnancy, childbirth and the puerperium
0.005 0.995 0.000
O98.2 Gonorrhoea complicating pregnancy, childbirth and the puerperium
0.005 0.995 0.000
O98.1 Syphilis complicating pregnancy, childbirth and the puerperium
0.005 0.995 0.000
O98.0 Tuberculosis complicating pregnancy, childbirth and the puerperium
0.005 0.995 0.000
I51.5 Myocardial degeneration
0.000 0.995 0.005
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.995 0.005
H92.2 Otorrhagia
0.000 0.995 0.005
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity
0.000 0.995 0.005
O96.9 Death from unspecified obstetric cause
0.005 0.995 0.000
O96.1 Death from indirect obstetric cause
0.005 0.995 0.000
O96.0 Death from direct obstetric cause
0.005 0.995 0.000
O97.9 Death from sequelae of obstetric cause, unspecified
0.005 0.995 0.000
O97.1 Death from sequelae of indirect obstetric cause
0.005 0.995 0.000
O97.0 Death from sequelae of direct obstetric cause
0.005 0.995 0.000
H33.3 Retinal breaks without detachment
0.000 0.995 0.005
H92.0 Otalgia
0.000 0.995 0.005
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.995 0.005
M79.00 Rheumatism, unspecified (Multiple sites)
0.000 0.995 0.005
H95.1 Other disorders following mastoidectomy
0.000 0.995 0.005
M24.16 Other articular cartilage disorders (Lower leg)
0.000 0.995 0.005
H95.9 Postprocedural disorder of ear and mastoid process, unspecified
0.000 0.995 0.005
H95.8 Other postprocedural disorders of ear and mastoid process
0.000 0.995 0.005
O98.8 Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium
0.005 0.995 0.000
E53.8 Deficiency of other specified B group vitamins
0.000 0.995 0.004
H02.4 Ptosis of eyelid
0.000 0.995 0.005
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.000 0.995 0.005
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.995 0.005
E04.1 Non-toxic single thyroid nodule
0.000 0.995 0.004
H80-H83 Diseases of inner ear
0.000 0.995 0.004
H94.8 Other specified disorders of ear in diseases classified elsewhere
0.000 0.995 0.004
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere
0.000 0.995 0.004
G47.3 Sleep apnoea
0.000 0.996 0.004
H93 Other disorders of ear, not elsewhere classified
0.000 0.996 0.004
H62 Disorders of external ear in diseases classified elsewhere
0.000 0.996 0.004
Q54.1 Hypospadias, penile
0.004 0.996 0.000
E20-E35 Disorders of other endocrine glands
0.000 0.996 0.004
G50 Disorders of trigeminal nerve
0.004 0.996 0.000
Q43 Other congenital malformations of intestine
0.004 0.996 0.000
Q43.9 Congenital malformation of intestine, unspecified
0.004 0.996 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.004 0.996 0.000
Q38.7 Pharyngeal pouch
0.004 0.996 0.000
Q54 Hypospadias
0.004 0.996 0.000
H93.9 Disorder of ear, unspecified
0.000 0.996 0.004
G50.8 Other disorders of trigeminal nerve
0.004 0.996 0.000
F20.9 Schizophrenia, unspecified
0.000 0.996 0.004
M41.99 Scoliosis, unspecified (Site unspecified)
0.000 0.996 0.004
I33.0 Acute and subacute infective endocarditis
0.000 0.996 0.004
Q51.3 Bicornate uterus
0.004 0.996 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.004 0.996 0.000
Q43.3 Congenital malformations of intestinal fixation
0.004 0.996 0.000
Q38.6 Other congenital malformations of mouth
0.003 0.996 0.000
H82 Vertiginous syndromes in diseases classified elsewhere
0.000 0.996 0.003
G50.9 Disorder of trigeminal nerve, unspecified
0.003 0.996 0.000
Q43.0 Meckel's diverticulum
0.003 0.996 0.000
Q54.9 Hypospadias, unspecified
0.003 0.997 0.000
H93.2 Other abnormal auditory perceptions
0.000 0.997 0.003
H93.0 Degenerative and vascular disorders of ear
0.000 0.997 0.003
Q43.1 Hirschsprung's disease
0.003 0.997 0.000
H62.8 Other disorders of external ear in diseases classified elsewhere
0.000 0.997 0.003
H62.4 Otitis externa in other diseases classified elsewhere
0.000 0.997 0.003
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere
0.000 0.997 0.003
H62.2 Otitis externa in mycoses
0.000 0.997 0.003
H62.1 Otitis externa in viral diseases classified elsewhere
0.000 0.997 0.003
H62.0 Otitis externa in bacterial diseases classified elsewhere
0.000 0.997 0.003
I51.7 Cardiomegaly
0.000 0.997 0.003
E26 Hyperaldosteronism
0.000 0.997 0.003
Q51 Congenital malformations of uterus and cervix
0.003 0.997 0.000
H93.3 Disorders of acoustic nerve
0.000 0.997 0.003
M79.09 Rheumatism, unspecified (Site unspecified)
0.000 0.997 0.003
F25 Schizoaffective disorders
0.000 0.997 0.003
F25.9 Schizoaffective disorder, unspecified
0.000 0.997 0.003
M79.0 Rheumatism, unspecified
0.000 0.997 0.003
Q54.0 Hypospadias, balanic
0.003 0.997 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.997 0.003
E32 Diseases of thymus
0.000 0.997 0.003
E31 Polyglandular dysfunction
0.000 0.997 0.003
E30 Disorders of puberty, not elsewhere classified
0.000 0.997 0.003
Q50-Q56 Congenital malformations of genital organs
0.003 0.997 0.000
G25.8 Other specified extrapyramidal and movement disorders
0.003 0.997 0.000
Q43.7 Persistent cloaca
0.003 0.997 0.000
Q43.6 Congenital fistula of rectum and anus
0.003 0.997 0.000
Q43.5 Ectopic anus
0.003 0.997 0.000
Q43.4 Duplication of intestine
0.003 0.997 0.000
Q43.2 Other congenital functional disorders of colon
0.003 0.997 0.000
M65.34 Trigger finger-Hand
0.003 0.997 0.000
H93.8 Other specified disorders of ear
0.000 0.997 0.003
F25.1 Schizoaffective disorder, depressive type
0.000 0.997 0.003
Z73.9 Problem related to life-management difficulty, unspecified
0.003 0.997 0.000
Q43.8 Other specified congenital malformations of intestine
0.003 0.997 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.000 0.997 0.003
Q38.8 Other congenital malformations of pharynx
0.003 0.997 0.000
Q38.5 Congenital malformations of palate, not elsewhere classified
0.003 0.997 0.000
Q38.4 Congenital malformations of salivary glands and ducts
0.003 0.997 0.000
Q38.3 Other congenital malformations of tongue
0.003 0.997 0.000
Q38.2 Macroglossia
0.003 0.997 0.000
Q38.1 Ankyloglossia
0.003 0.997 0.000
Q38.0 Congenital malformations of lips, not elsewhere classified
0.003 0.997 0.000
E20 Hypoparathyroidism
0.000 0.997 0.003
Q54.8 Other hypospadias
0.003 0.997 0.000
Q54.4 Congenital chordee
0.003 0.997 0.000
Q54.3 Hypospadias, perineal
0.003 0.997 0.000
Q54.2 Hypospadias, penoscrotal
0.003 0.997 0.000
E25 Adrenogenital disorders
0.000 0.997 0.003
O47.0 False labour before 37 completed weeks of gestation
0.003 0.997 0.000
Q82 Other congenital malformations of skin
0.003 0.997 0.000
Q83.1 Accessory breast
0.003 0.997 0.000
H91 Other hearing loss
0.000 0.997 0.003
N13.5 Kinking and stricture of ureter without hydronephrosis
0.003 0.997 0.000
Q82.5 Congenital nonneoplastic naevus
0.003 0.997 0.000
F25.0 Schizoaffective disorder, manic type
0.000 0.997 0.003
F20 Schizophrenia
0.000 0.997 0.003
Q40 Other congenital malformations of upper alimentary tract
0.003 0.997 0.000
Q45 Other congenital malformations of digestive system
0.003 0.997 0.000
M79.08 Rheumatism, unspecified (Other)
0.000 0.997 0.003
M81.90 Osteoporosis, unspecified (Multiple sites)
0.003 0.997 0.000
G50.1 Atypical facial pain
0.003 0.997 0.000
K66.8 Other specified disorders of peritoneum
0.003 0.997 0.000
Q42 Congenital absence, atresia and stenosis of large intestine
0.003 0.997 0.000
Q41 Congenital absence, atresia and stenosis of small intestine
0.003 0.997 0.000
Q83 Congenital malformations of breast
0.003 0.997 0.000
Q80-Q89 Other congenital malformations
0.003 0.997 0.000
E34 Other endocrine disorders
0.000 0.997 0.003
E24 Cushing's syndrome
0.000 0.997 0.003
N92.5 Other specified irregular menstruation
0.003 0.997 0.000
E26.0 Primary hyperaldosteronism
0.000 0.997 0.003
H80 Otosclerosis
0.000 0.997 0.003
Q05.9 Spina bifida, unspecified
0.003 0.997 0.000
E29 Testicular dysfunction
0.000 0.997 0.003
D52.9 Folate deficiency anaemia, unspecified
0.003 0.997 0.000
E26.9 Hyperaldosteronism, unspecified
0.000 0.997 0.002
E26.8 Other hyperaldosteronism
0.000 0.997 0.002
E26.1 Secondary hyperaldosteronism
0.000 0.997 0.002
Q51.2 Other doubling of uterus
0.003 0.997 0.000
M79.19 Myalgia (Site unspecified)
0.003 0.997 0.000
Q51.9 Congenital malformation of uterus and cervix, unspecified
0.003 0.997 0.000
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts
0.003 0.997 0.000
Q51.6 Embryonic cyst of cervix
0.003 0.997 0.000
Q51.5 Agenesis and aplasia of cervix
0.003 0.997 0.000
Q51.4 Unicornate uterus
0.003 0.997 0.000
Q51.1 Doubling of uterus with doubling of cervix and vagina
0.003 0.997 0.000
Q51.0 Agenesis and aplasia of uterus
0.003 0.997 0.000
F25.8 Other schizoaffective disorders
0.000 0.997 0.003
F25.2 Schizoaffective disorder, mixed type
0.000 0.997 0.003
Z46.2 Fitting and adjustment of other devices related to nervous system and special senses
0.003 0.997 0.000
Q05 Spina bifida
0.003 0.997 0.000
M79.07 Rheumatism, unspecified (Ankle and foot)
0.000 0.997 0.002
M79.05 Rheumatism, unspecified (Pelvic region and thigh)
0.000 0.997 0.002
M79.04 Rheumatism, unspecified (Hand)
0.000 0.997 0.002
M79.03 Rheumatism, unspecified (Forearm)
0.000 0.997 0.002
M79.02 Rheumatism, unspecified (Upper arm)
0.000 0.997 0.002
Q82.2 Mastocytosis
0.003 0.997 0.000
E30.9 Disorder of puberty, unspecified
0.000 0.997 0.002
E30.8 Other disorders of puberty
0.000 0.997 0.002
E30.1 Precocious puberty
0.000 0.997 0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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