TreeWAS – Variant ID: rs11053548

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.928	0.072
D68.2 Hereditary deficiency of other clotting factors	0.000	0.936	0.064
N18.5 Chronic kidney disease, stage 5	0.051	0.949	0.000
M06.9 Rheumatoid arthritis, unspecified	0.000	0.961	0.039
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.964	0.036
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.967	0.033
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.969	0.031
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.969	0.031
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.970	0.030
D68 Other coagulation defects	0.000	0.972	0.028
K29.5 Chronic gastritis, unspecified	0.000	0.972	0.028
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.000	0.974	0.026
D68.5 Primary Thrombophilia	0.000	0.976	0.024
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.976	0.024
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.976	0.024
D06.9 Cervix, unspecified	0.023	0.977	0.000
S64.4 Injury of digital nerve of other finger	0.022	0.978	0.000
H53.2 Diplopia	0.000	0.978	0.022
D68.1 Hereditary factor XI deficiency	0.000	0.979	0.020
D68.4 Acquired coagulation factor deficiency	0.000	0.980	0.020
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.020	0.980	0.000
D68.6 Other Thrombophilia	0.000	0.982	0.017
D68.8 Other specified coagulation defects	0.000	0.983	0.017
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.016	0.984	0.000
D68.0 Von Willebrand's disease	0.000	0.985	0.015
S64 Injury of nerves at wrist and hand level	0.015	0.985	0.000
H53 Visual disturbances	0.000	0.986	0.014
H53.0 Amblyopia ex anopsia	0.000	0.987	0.013
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.013	0.987	0.000
S64.2 Injury of radial nerve at wrist and hand level	0.013	0.987	0.000
T42.1 Iminostilbenes	0.013	0.987	0.000
S32.50 Fracture of pubis (closed)	0.000	0.987	0.013
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.012	0.988	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.001	0.988	0.011
S64.3 Injury of digital nerve of thumb	0.012	0.988	0.000
S64.0 Injury of ulnar nerve at wrist and hand level	0.012	0.988	0.000
D06 Carcinoma in situ of cervix uteri	0.011	0.988	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.011	0.989	0.000
T42.3 Barbiturates	0.011	0.989	0.000
T42.2 Succinimides and oxazolidinediones	0.011	0.989	0.000
H53.1 Subjective visual disturbances	0.000	0.989	0.011
T42.0 Hydantoin derivatives	0.011	0.989	0.000
S64.9 Injury of unspecified nerve at wrist and hand level	0.011	0.989	0.000
S64.8 Injury of other nerves at wrist and hand level	0.011	0.989	0.000
S64.7 Injury of multiple nerves at wrist and hand level	0.011	0.989	0.000
H53.6 Night blindness	0.000	0.990	0.010
H53.5 Colour vision deficiencies	0.000	0.990	0.010
H53.3 Other disorders of binocular vision	0.000	0.990	0.010
S32.5 Fracture of pubis	0.000	0.990	0.010
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.009	0.991	0.000
R22.2 Localised swelling, mass and lump, trunk	0.000	0.991	0.009
T36-T50 Poisoning by drugs, medicaments and biological substances	0.009	0.991	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.991	0.009
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.000	0.991	0.009
M06 Other rheumatoid arthritis	0.000	0.991	0.009
T42.4 Benzodiazepines	0.009	0.991	0.000
S64.1 Injury of median nerve at wrist and hand level	0.009	0.991	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.009	0.991	0.000
R22.3 Localised swelling, mass and lump, upper limb	0.000	0.991	0.009
D06.0 Endocervix	0.008	0.991	0.000
D06.7 Other parts of cervix	0.008	0.991	0.000
D06.1 Exocervix	0.008	0.991	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.008	0.992	0.000
H53.8 Other visual disturbances	0.000	0.992	0.008
H53.4 Visual field defects	0.000	0.992	0.008
H53.9 Visual disturbance, unspecified	0.000	0.992	0.008
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.008	0.992	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.008	0.992	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.008	0.992	0.000
S32 Fracture of lumbar spine and pelvis	0.000	0.993	0.007
T36 Poisoning by systemic antibiotics	0.007	0.993	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.007	0.993	0.000
D66 Hereditary factor VIII deficiency	0.000	0.993	0.007
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.000	0.993	0.007
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.007	0.993	0.000
K29.4 Chronic atrophic gastritis	0.000	0.993	0.007
S32.51 Fracture of pubis (open)	0.000	0.993	0.007
D68.9 Coagulation defect, unspecified	0.000	0.993	0.007
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.007	0.993	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.007	0.993	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.007	0.993	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.007	0.993	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.007	0.993	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.007	0.993	0.000
T44.0 Anticholinesterase agents	0.007	0.993	0.000
S32.0 Fracture of lumbar vertebra	0.000	0.993	0.007
R22.9 Localised swelling, mass and lump, unspecified	0.000	0.993	0.007
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.007	0.993	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.007	0.993	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.007	0.993	0.000
D67 Hereditary factor IX deficiency	0.000	0.993	0.007
M06.2 Rheumatoid bursitis	0.000	0.993	0.007
M06.1 Adult-onset Still's disease	0.000	0.993	0.007
M06.4 Inflammatory polyarthropathy	0.000	0.993	0.007
S32.00 Fracture of lumbar vertebra (closed)	0.000	0.993	0.007
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.000	0.993	0.007
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.006	0.993	0.000
M06.8 Other specified rheumatoid arthritis	0.000	0.994	0.006
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.006	0.994	0.000
T50.1 Loop [high-ceiling] diuretics	0.006	0.994	0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.000	0.994	0.006
M06.3 Rheumatoid nodule	0.000	0.994	0.006
T46.5 Other antihypertensive drugs, not elsewhere classified	0.006	0.994	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.006	0.994	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.006	0.994	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.006	0.994	0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified	0.000	0.994	0.006
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.006	0.994	0.000
T38.1 Thyroid hormones and substitutes	0.006	0.994	0.000
R22.7 Localised swelling, mass and lump, multiple sites	0.000	0.994	0.006
T36.0 Penicillins	0.006	0.994	0.000
S32.7 Multiple fractures of lumbar spine and pelvis	0.000	0.994	0.006
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.006	0.994	0.000
T36.3 Macrolides	0.006	0.994	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.006	0.994	0.000
R22.0 Localised swelling, mass and lump, head	0.000	0.994	0.006
T37.8 Other specified systemic anti-infectives and antiparasitics	0.006	0.994	0.000
T38.9 Other and unspecified hormone antagonists	0.006	0.994	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.006	0.994	0.000
T38.7 Androgens and anabolic congeners	0.006	0.994	0.000
T38.5 Other oestrogens and progestogens	0.006	0.994	0.000
T38.4 Oral contraceptives	0.006	0.994	0.000
T38.2 Antithyroid drugs	0.006	0.994	0.000
T38.0 Glucocorticoids and synthetic analogues	0.006	0.994	0.000
S32.3 Fracture of ilium	0.000	0.994	0.006
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.006	0.994	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.006	0.994	0.000
T46.7 Peripheral vasodilators	0.006	0.994	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.006	0.994	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.006	0.994	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.006	0.994	0.000
T50.7 Analeptics and opioid receptor antagonists	0.006	0.994	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.006	0.994	0.000
T50.5 Appetite depressants	0.006	0.994	0.000
T50.4 Drugs affecting uric acid metabolism	0.006	0.994	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.006	0.994	0.000
T50.0 Mineralocorticoids and their antagonists	0.006	0.994	0.000
S32.1 Fracture of sacrum	0.000	0.994	0.006
S32.2 Fracture of coccyx	0.000	0.994	0.006
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.006	0.994	0.000
T36.9 Systemic antibiotic, unspecified	0.005	0.994	0.000
T36.8 Other systemic antibiotics	0.005	0.994	0.000
T36.7 Antifungal antibiotics, systemically used	0.005	0.994	0.000
T36.6 Rifamycins	0.005	0.994	0.000
T36.5 Aminoglycosides	0.005	0.994	0.000
T36.4 Tetracyclines	0.005	0.994	0.000
T36.2 Chloramphenicol group	0.005	0.994	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.005	0.994	0.000
T46.1 Calcium-channel blockers	0.005	0.994	0.000
S32.80 Fracture of other and unspecified parts of lumbar spine and pelvis (closed)	0.000	0.994	0.005
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.005	0.995	0.000
T37.5 Antiviral drugs	0.005	0.995	0.000
T37.4 Anthelminthics	0.005	0.995	0.000
T37.3 Other antiprotozoal drugs	0.005	0.995	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.005	0.995	0.000
T37.1 Antimycobacterial drugs	0.005	0.995	0.000
T37.0 Sulphonamides	0.005	0.995	0.000
S32.01 Fracture of lumbar vertebra (open)	0.000	0.995	0.005
T50.8 Diagnostic agents	0.005	0.995	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.000	0.995	0.005
T41.5 Therapeutic gases	0.005	0.995	0.000
T41.4 Anaesthetic, unspecified	0.005	0.995	0.000
T41.3 Local anaesthetics	0.005	0.995	0.000
T41.2 Other and unspecified general anaesthetics	0.005	0.995	0.000
T41.1 Intravenous anaesthetics	0.005	0.995	0.000
T41.0 Inhaled anaesthetics	0.005	0.995	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.005	0.995	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.005	0.995	0.000
T48.5 Anti-common-cold drugs	0.005	0.995	0.000
T48.4 Expectorants	0.005	0.995	0.000
T48.3 Antitussives	0.005	0.995	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.005	0.995	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.005	0.995	0.000
T48.0 Oxytocic drugs	0.005	0.995	0.000
T49.9 Topical agent, unspecified	0.005	0.995	0.000
T49.8 Other topical agents	0.005	0.995	0.000
T49.7 Dental drugs, topically applied	0.005	0.995	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.005	0.995	0.000
T49.5 Ophthalmological drugs and preparations	0.005	0.995	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.005	0.995	0.000
T49.3 Emollients, demulcents and protectants	0.005	0.995	0.000
T49.2 Local astringents and local detergents	0.005	0.995	0.000
T49.1 Antipruritics	0.005	0.995	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.005	0.995	0.000
T47.0 Histamine H(2)-receptor antagonists	0.005	0.995	0.000
M06.19 Adult-onset Still's disease (Site unspecified)	0.000	0.995	0.005
M06.18 Adult-onset Still's disease (Other)	0.000	0.995	0.005
M06.17 Adult-onset Still's disease (Ankle and foot)	0.000	0.995	0.005
M06.16 Adult-onset Still's disease (Lower leg)	0.000	0.995	0.005
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.000	0.995	0.005
M06.14 Adult-onset Still's disease (Hand)	0.000	0.995	0.005
M06.13 Adult-onset Still's disease (Forearm)	0.000	0.995	0.005
M06.12 Adult-onset Still's disease (Upper arm)	0.000	0.995	0.005
M06.11 Adult-onset Still's disease (Shoulder region)	0.000	0.995	0.005
M06.10 Adult-onset Still's disease (Multiple sites)	0.000	0.995	0.005
M06.29 Rheumatoid bursitis (Site unspecified)	0.000	0.995	0.005
M06.28 Rheumatoid bursitis (Other)	0.000	0.995	0.005
M06.27 Rheumatoid bursitis (Ankle and foot)	0.000	0.995	0.005
M06.26 Rheumatoid bursitis (Lower leg)	0.000	0.995	0.005
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.000	0.995	0.005
M06.24 Rheumatoid bursitis (Hand)	0.000	0.995	0.005
M06.23 Rheumatoid bursitis (Forearm)	0.000	0.995	0.005
M06.22 Rheumatoid bursitis (Upper arm)	0.000	0.995	0.005
M06.21 Rheumatoid bursitis (Shoulder region)	0.000	0.995	0.005
M06.20 Rheumatoid bursitis (Multiple sites)	0.000	0.995	0.005
M06.48 Inflammatory polyarthropathy (Other)	0.000	0.995	0.005
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.000	0.995	0.005
M06.46 Inflammatory polyarthropathy (Lower leg)	0.000	0.995	0.005
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.000	0.995	0.005
M06.44 Inflammatory polyarthropathy (Hand)	0.000	0.995	0.005
M06.43 Inflammatory polyarthropathy (Forearm)	0.000	0.995	0.005
M06.42 Inflammatory polyarthropathy (Upper arm)	0.000	0.995	0.005
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.000	0.995	0.005
T43.3 Phenothiazine antipsychotics and neuroleptics	0.005	0.995	0.000
S32.4 Fracture of acetabulum	0.000	0.995	0.005
T43.5 Other and unspecified antipsychotics and neuroleptics	0.005	0.995	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.005	0.995	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.005	0.995	0.000
T47.7 Emetics	0.005	0.995	0.000
T47.6 Antidiarrhoeal drugs	0.005	0.995	0.000
T47.5 Digestants	0.005	0.995	0.000
T47.4 Other laxatives	0.005	0.995	0.000
T47.3 Saline and osmotic laxatives	0.005	0.995	0.000
T47.2 Stimulant laxatives	0.005	0.995	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.000	0.995	0.005
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.000	0.995	0.005
M06.37 Rheumatoid nodule (Ankle and foot)	0.000	0.995	0.005
M06.88 Other specified rheumatoid arthritis (Other)	0.000	0.995	0.005
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.000	0.995	0.005
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.000	0.995	0.005
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.000	0.995	0.005
M06.84 Other specified rheumatoid arthritis (Hand)	0.000	0.995	0.005
M06.83 Other specified rheumatoid arthritis (Forearm)	0.000	0.995	0.005
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.000	0.995	0.005
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.000	0.995	0.005
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.000	0.995	0.005
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.000	0.995	0.005
S32.81 Fracture of other and unspecified parts of lumbar spine and pelvis (open)	0.000	0.995	0.005
M06.39 Rheumatoid nodule (Site unspecified)	0.000	0.995	0.005
M06.38 Rheumatoid nodule (Other)	0.000	0.995	0.005
M06.36 Rheumatoid nodule (Lower leg)	0.000	0.995	0.005
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.000	0.995	0.005
M06.33 Rheumatoid nodule (Forearm)	0.000	0.995	0.005
M06.31 Rheumatoid nodule (Shoulder region)	0.000	0.995	0.005
M06.30 Rheumatoid nodule (Multiple sites)	0.000	0.995	0.005
D21.2 Connective and other soft tissue of lower limb, including hip	0.000	0.995	0.005
T40.5 Cocaine	0.005	0.995	0.000
D07.1 Vulva	0.005	0.995	0.000
S32.30 Fracture of ilium (closed)	0.000	0.995	0.004
T43.2 Other and unspecified antidepressants	0.005	0.995	0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.000	0.995	0.004
T43.9 Psychotropic drug, unspecified	0.004	0.995	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.004	0.995	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.004	0.995	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.004	0.995	0.000
S32.71 Multiple fractures of lumbar spine and pelvis (open)	0.000	0.995	0.004
T40.1 Heroin	0.004	0.995	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.004	0.996	0.000
S32.31 Fracture of ilium (open)	0.000	0.996	0.004
B37.3 Candidiasis of vulva and vagina	0.000	0.996	0.004
S32.11 Fracture of sacrum (open)	0.000	0.996	0.004
S32.10 Fracture of sacrum (closed)	0.000	0.996	0.004
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.004	0.996	0.000
T40.8 Lysergide [LSD]	0.004	0.996	0.000
T40.7 Cannabis (derivatives)	0.004	0.996	0.000
T40.3 Methadone	0.004	0.996	0.000
T40.0 Opium	0.004	0.996	0.000
S32.21 Fracture of coccyx (open)	0.000	0.996	0.004
S32.20 Fracture of coccyx (closed)	0.000	0.996	0.004
M43.16 Spondylolisthesis (Lumbar region)	0.004	0.996	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.004	0.996	0.000
M06.0 Seronegative rheumatoid arthritis	0.000	0.996	0.004
T40.6 Other and unspecified narcotics	0.004	0.996	0.000
A63.0 Anogenital (venereal) warts	0.004	0.996	0.000
D69 Purpura and other haemorrhagic conditions	0.000	0.996	0.004
K29 Gastritis and duodenitis	0.000	0.996	0.004
S32.41 Fracture of acetabulum (open)	0.000	0.996	0.004
T43.6 Psychostimulants with abuse potential	0.004	0.996	0.000
M06.34 Rheumatoid nodule (Hand)	0.000	0.996	0.004
D59.1 Other autoimmune haemolytic anaemias	0.000	0.996	0.004
D07 Carcinoma in situ of other and unspecified genital organs	0.004	0.996	0.000
D07.2 Vagina	0.004	0.996	0.000
K29.3 Chronic superficial gastritis	0.000	0.996	0.004
T45.2 Vitamins, not elsewhere classified	0.003	0.996	0.000
J11.1 Influenza with other respiratory manifestations, virus not identified	0.004	0.996	0.000
K04.7 Periapical abscess without sinus	0.004	0.996	0.000
T40.4 Other synthetic narcotics	0.003	0.996	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.003	0.996	0.000
T45.8 Other primarily systemic and haematological agents	0.003	0.996	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.003	0.996	0.000
T45.6 Fibrinolysis-affecting drugs	0.003	0.996	0.000
T45.5 Anticoagulants	0.003	0.996	0.000
T45.4 Iron and its compounds	0.003	0.996	0.000
T45.3 Enzymes, not elsewhere classified	0.003	0.996	0.000
D69.4 Other primary thrombocytopenia	0.000	0.996	0.003
E78.8 Other disorders of lipoprotein metabolism	0.004	0.996	0.000
S72.10 Pertrochanteric fracture (closed)	0.004	0.996	0.000
T40.2 Other opioids	0.003	0.997	0.000
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history	0.000	0.997	0.003
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.000	0.997	0.003
D05.1 Intraductal carcinoma in situ	0.003	0.997	0.000
K29.2 Alcoholic gastritis	0.000	0.997	0.003
C71.1 Frontal lobe	0.000	0.997	0.003
K82.8 Other specified diseases of gallbladder	0.003	0.997	0.000
D69.9 Haemorrhagic condition, unspecified	0.000	0.997	0.003
H52.0 Hypermetropia	0.000	0.997	0.003
M06.08 Seronegative rheumatoid arthritis (Other)	0.000	0.997	0.003
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.000	0.997	0.003
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.000	0.997	0.003
M06.04 Seronegative rheumatoid arthritis (Hand)	0.000	0.997	0.003
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.000	0.997	0.003
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.000	0.997	0.003
D69.0 Allergic purpura	0.000	0.997	0.003
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified	0.003	0.997	0.000
D00-D09 In situ neoplasms	0.003	0.997	0.000
S32.40 Fracture of acetabulum (closed)	0.000	0.997	0.003
T43.0 Tricyclic and tetracyclic antidepressants	0.003	0.997	0.000
H53-H54 Visual disturbances and blindness	0.000	0.997	0.003
H50.9 Strabismus, unspecified	0.000	0.997	0.003
D69.8 Other specified haemorrhagic conditions	0.000	0.997	0.003
D69.1 Qualitative platelet defects	0.000	0.997	0.003
Z35.8 Supervision of other high-risk pregnancies	0.000	0.997	0.003
H50.1 Divergent concomitant strabismus	0.000	0.997	0.003
K29.9 Gastroduodenitis, unspecified	0.000	0.997	0.003
Z35.1 Supervision of pregnancy with history of abortive outcome	0.000	0.997	0.003
D69.2 Other nonthrombocytopenic purpura	0.000	0.997	0.003
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.000	0.997	0.003
D07.6 Other and unspecified male genital organs	0.003	0.997	0.000
D07.3 Other and unspecified female genital organs	0.003	0.997	0.000
D07.0 Endometrium	0.003	0.997	0.000
N77.1 Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere	0.000	0.997	0.003
Y84.1 Kidney dialysis	0.003	0.997	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.000	0.997	0.003
T45.1 Antineoplastic and immunosuppressive drugs	0.003	0.997	0.000
D59 Acquired haemolytic anaemia	0.000	0.997	0.003
Z35 Supervision of high-risk pregnancy	0.000	0.997	0.003
H50 Other strabismus	0.000	0.997	0.003
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.003	0.997	0.000
D09 Carcinoma in situ of other and unspecified sites	0.003	0.997	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.000	0.997	0.003
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.003	0.997	0.000
Z35.4 Supervision of pregnancy with grand multiparity	0.000	0.997	0.003
D05 Carcinoma in situ of breast	0.003	0.997	0.000
D01 Carcinoma in situ of other and unspecified digestive organs	0.002	0.997	0.000
A04.7 Enterocolitis due to Clostridium difficile	0.003	0.997	0.000
C83.3 Large cell (diffuse)	0.003	0.997	0.000
R61.9 Hyperhidrosis, unspecified	0.000	0.997	0.002
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.002	0.998	0.000
H50.8 Other specified strabismus	0.000	0.998	0.002
H50.0 Convergent concomitant strabismus	0.000	0.998	0.002
H50.4 Other and unspecified heterotropia	0.000	0.998	0.002
D00.0 Lip, oral cavity and pharynx	0.002	0.998	0.000
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)	0.002	0.998	0.000
C16.0 Cardia	0.000	0.998	0.002
Z35.0 Supervision of pregnancy with history of infertility	0.000	0.998	0.002
D59.8 Other acquired haemolytic anaemias	0.000	0.998	0.002
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.000	0.998	0.002
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.000	0.998	0.002
D59.4 Other nonautoimmune haemolytic anaemias	0.000	0.998	0.002
D59.3 Haemolytic-uraemic syndrome	0.000	0.998	0.002
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.000	0.998	0.002
D59.0 Drug-induced autoimmune haemolytic anaemia	0.000	0.998	0.002
Z35.7 Supervision of high-risk pregnancy due to social problems	0.000	0.998	0.002
Z35.6 Supervision of very young primigravida	0.000	0.998	0.002
Z35.3 Supervision of pregnancy with history of insufficient antenatal care	0.000	0.998	0.002
D00.1 Oesophagus	0.002	0.998	0.000
D09.0 Bladder	0.002	0.998	0.000
H50.6 Mechanical strabismus	0.000	0.998	0.002
H50.3 Intermittent heterotropia	0.000	0.998	0.002
O46.9 Antepartum haemorrhage, unspecified	0.000	0.998	0.002
B37.8 Candidiasis of other sites	0.000	0.998	0.002
S91.3 Open wound of other parts of foot	0.002	0.998	0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.002	0.998	0.000
D00.2 Stomach	0.002	0.998	0.000
D07.4 Penis	0.002	0.998	0.000
M23.8 Other internal derangements of knee	0.002	0.998	0.000
B37 Candidiasis	0.000	0.998	0.002
D75.1 Secondary polycythaemia	0.000	0.998	0.002
D02 Carcinoma in situ of middle ear and respiratory system	0.002	0.998	0.000
D09.1 Other and unspecified urinary organs	0.002	0.998	0.000
D75.2 Essential thrombocytosis	0.000	0.998	0.002
D09.9 Carcinoma in situ, unspecified	0.002	0.998	0.000
D09.7 Carcinoma in situ of other specified sites	0.002	0.998	0.000
D09.3 Thyroid and other endocrine glands	0.002	0.998	0.000
D09.2 Eye	0.002	0.998	0.000
T45.0 Antiallergic and antiemetic drugs	0.002	0.998	0.001
B37.4 Candidiasis of other urogenital sites	0.000	0.998	0.002
D07.5 Prostate	0.002	0.998	0.000
H49.2 Sixth [abducent] nerve palsy	0.000	0.998	0.002
C45.7 Mesothelioma of other sites	0.002	0.998	0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.000	0.998	0.002
C44.7 Skin of lower limb, including hip	0.002	0.998	0.000
D75 Other diseases of blood and blood-forming organs	0.000	0.998	0.002
D01.9 Digestive organ, unspecified	0.002	0.998	0.000
D01.7 Other specified digestive organs	0.002	0.998	0.000
D01.5 Liver, gallbladder and bile ducts	0.002	0.998	0.000
D01.4 Other and unspecified parts of intestine	0.002	0.998	0.000
D01.2 Rectum	0.002	0.998	0.000
D01.1 Rectosigmoid junction	0.002	0.998	0.000
D01.0 Colon	0.002	0.998	0.000
R82.9 Other and unspecified abnormal finding in urine	0.002	0.998	0.000
R82.8 Abnormal findings on cytological and histological examination of urine	0.002	0.998	0.000
D01.3 Anus and anal canal	0.002	0.998	0.000
N18.3 Chronic kidney disease, stage 3	0.000	0.998	0.002
M00.96 Pyogenic arthritis, unspecified (Lower leg)	0.000	0.998	0.002
D75.0 Familial erythrocytosis	0.000	0.998	0.002
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.000	0.998	0.002
R22.1 Localised swelling, mass and lump, neck	0.000	0.998	0.002
B37.1 Pulmonary candidiasis	0.000	0.998	0.002
D69.6 Thrombocytopenia, unspecified	0.000	0.998	0.002
D69.5 Secondary thrombocytopenia	0.000	0.998	0.002
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.998	0.002
A63.8 Other specified predominantly sexually transmitted diseases	0.002	0.998	0.000
C67.5 Bladder neck	0.002	0.998	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.000	0.998	0.002
Z35.9 Supervision of high-risk pregnancy, unspecified	0.000	0.998	0.002
I07.1 Tricuspid insufficiency	0.002	0.998	0.000
H52 Disorders of refraction and accommodation	0.000	0.998	0.002
D05.0 Lobular carcinoma in situ	0.002	0.998	0.000
C45.0 Mesothelioma of pleura	0.002	0.998	0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.002	0.998	0.000
G62.9 Polyneuropathy, unspecified	0.002	0.998	0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.002	0.998	0.000
C67.0 Trigone of bladder	0.002	0.998	0.000
H52.3 Anisometropia and aniseikonia	0.000	0.998	0.002
W29.9 Unspecified place	0.002	0.998	0.000
O75.0 Maternal distress during labour and delivery	0.000	0.998	0.002
S31.8 Open wound of other and unspecified parts of abdomen	0.002	0.998	0.000
Z96.7 Presence of other bone and tendon implants	0.002	0.998	0.000
O75.8 Other specified complications of labour and delivery	0.000	0.998	0.002
H50.5 Heterophoria	0.000	0.998	0.002
M23.87 Other internal derangements of knee (Capsular ligament)	0.002	0.998	0.000
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)	0.002	0.998	0.000
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.002	0.998	0.000
B37.7 Candidal septicaemia	0.000	0.998	0.002
B37.6 Candidal endocarditis	0.000	0.998	0.002
B37.5 Candidal meningitis	0.000	0.998	0.002
D02.4 Respiratory system, unspecified	0.002	0.998	0.000
D02.3 Other parts of respiratory system	0.002	0.998	0.000
D02.2 Bronchus and lung	0.002	0.998	0.000
D02.1 Trachea	0.002	0.998	0.000
H50.2 Vertical strabismus	0.000	0.998	0.002
C45 Mesothelioma	0.002	0.998	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.000	0.998	0.002
M00.94 Pyogenic arthritis, unspecified (Hand)	0.000	0.998	0.002
M23.80 Other internal derangements of knee (Multiple sites)	0.002	0.998	0.000
O75.7 Vaginal delivery following previous Caesarean section	0.000	0.998	0.002
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.002	0.998	0.000
R82.5 Elevated urine levels of drugs, medicaments and biological substances	0.002	0.998	0.000
Z41.1 Other plastic surgery for unacceptable cosmetic appearance	0.000	0.998	0.002
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.002	0.998	0.000
O73.0 Retained placenta, without haemorrhage	0.002	0.998	0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.002	0.998	0.000
R82 Other abnormal findings in urine	0.002	0.998	0.000
Z83.3 Family history of diabetes mellitus	0.002	0.998	0.000
K29.1 Other acute gastritis	0.000	0.998	0.002
D05.7 Other carcinoma in situ of breast	0.002	0.998	0.000
M00.9 Pyogenic arthritis, unspecified	0.000	0.998	0.002
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.000	0.998	0.002
M71.38 Other bursal cyst (Other)	0.000	0.998	0.002
G58.9 Mononeuropathy, unspecified	0.002	0.998	0.000
A04.5 Campylobacter enteritis	0.002	0.998	0.000
S63.6 Sprain and strain of finger(s)	0.000	0.998	0.002
J11 Influenza, virus not identified	0.002	0.998	0.000
C45.9 Mesothelioma, unspecified	0.002	0.998	0.000
C67.4 Posterior wall of bladder	0.002	0.998	0.000
N83.1 Corpus luteum cyst	0.002	0.998	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.000	0.998	0.002
M00.90 Pyogenic arthritis, unspecified (Multiple sites)	0.000	0.998	0.002
C83 Diffuse non-Hodgkin's lymphoma	0.002	0.998	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.000	0.998	0.002
H49 Paralytic strabismus	0.000	0.998	0.002
D75.9 Disease of blood and blood-forming organs, unspecified	0.000	0.998	0.002
H52.6 Other disorders of refraction	0.000	0.998	0.002
H52.5 Disorders of accommodation	0.000	0.998	0.002
I25.3 Aneurysm of heart	0.000	0.998	0.002
K80.8 Other cholelithiasis	0.000	0.998	0.002
M43.1 Spondylolisthesis	0.002	0.998	0.000
M00.91 Pyogenic arthritis, unspecified (Shoulder region)	0.000	0.998	0.002
O46.8 Other antepartum haemorrhage	0.000	0.998	0.002
S72.1 Pertrochanteric fracture	0.002	0.998	0.000
M00.95 Pyogenic arthritis, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
C67.3 Anterior wall of bladder	0.002	0.998	0.000
H49.9 Paralytic strabismus, unspecified	0.000	0.998	0.002
H52.7 Disorder of refraction, unspecified	0.000	0.998	0.002
B37.2 Candidiasis of skin and nail	0.000	0.998	0.001
C45.2 Mesothelioma of pericardium	0.002	0.998	0.000
C45.1 Mesothelioma of peritoneum	0.002	0.998	0.000
G93.1 Anoxic brain damage, not elsewhere classified	0.002	0.998	0.000
J11.0 Influenza with pneumonia, virus not identified	0.002	0.998	0.000
M43.19 Spondylolisthesis (Site unspecified)	0.002	0.998	0.000
R82.1 Myoglobinuria	0.002	0.998	0.000
C67 Malignant neoplasm of bladder	0.002	0.998	0.000
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.002	0.998	0.000
H52.2 Astigmatism	0.000	0.998	0.002
I44.2 Atrioventricular block, complete	0.000	0.998	0.002
R82.6 Abnormal urine levels of substances chiefly nonmedicinal as to source	0.001	0.998	0.000
R82.3 Haemoglobinuria	0.001	0.998	0.000
R82.2 Biliuria	0.001	0.998	0.000
R82.0 Chyluria	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations