TreeWAS – Variant ID: rs1106634

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
N21.0 Calculus in bladder	0.033	0.967	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.019	0.981	0.000
R60.0 Localised oedema	0.000	0.981	0.019
J47 Bronchiectasis	0.018	0.982	0.000
N28.9 Disorder of kidney and ureter, unspecified	0.013	0.987	0.000
T40.2 Other opioids	0.011	0.989	0.000
N21 Calculus of lower urinary tract	0.011	0.989	0.000
N28 Other disorders of kidney and ureter, not elsewhere classified	0.011	0.989	0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances	0.000	0.989	0.011
N28.1 Cyst of kidney, acquired	0.010	0.990	0.000
D51 Vitamin B12 deficiency anaemia	0.010	0.990	0.000
Z00.0 General medical examination	0.000	0.990	0.010
N28.0 Ischaemia and infarction of kidney	0.009	0.991	0.000
N21.9 Calculus of lower urinary tract, unspecified	0.008	0.992	0.000
N21.8 Other lower urinary tract calculus	0.008	0.992	0.000
J35.0 Chronic tonsillitis	0.008	0.992	0.000
M22.2 Patellofemoral disorders	0.008	0.992	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.007	0.993	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.007	0.993	0.000
D51.2 Transcobalamin II deficiency	0.007	0.993	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.007	0.993	0.000
M22.8 Other disorders of patella	0.007	0.993	0.000
M22 Disorders of patella	0.007	0.993	0.000
H36.0 Diabetic retinopathy	0.000	0.993	0.007
D52.9 Folate deficiency anaemia, unspecified	0.007	0.993	0.000
N25-N29 Other disorders of kidney and ureter	0.007	0.993	0.000
M22.4 Chondromalacia patellae	0.006	0.993	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.006	0.994	0.000
E10.4 With neurological complications	0.000	0.994	0.006
N21.1 Calculus in urethra	0.006	0.994	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.006	0.994	0.000
D52 Folate deficiency anaemia	0.006	0.994	0.000
N28.8 Other specified disorders of kidney and ureter	0.006	0.994	0.000
E10.3 With ophthalmic complications	0.000	0.994	0.006
E10 Insulin-dependent diabetes mellitus	0.000	0.994	0.006
N29 Other disorders of kidney and ureter in diseases classified elsewhere	0.006	0.994	0.000
E10.5 With peripheral circulatory complications	0.000	0.994	0.006
D50-D53 Nutritional anaemias	0.006	0.994	0.000
N29.8 Other disorders of kidney and ureter in other diseases classified elsewhere	0.005	0.994	0.000
N25 Disorders resulting from impaired renal tubular function	0.005	0.994	0.000
M22.1 Recurrent subluxation of patella	0.005	0.995	0.000
M22.9 Disorder of patella, unspecified	0.005	0.995	0.000
M22.0 Recurrent dislocation of patella	0.005	0.995	0.000
J35 Chronic diseases of tonsils and adenoids	0.005	0.995	0.000
E10.0 With coma	0.000	0.995	0.005
J35.8 Other chronic diseases of tonsils and adenoids	0.005	0.995	0.000
T40.4 Other synthetic narcotics	0.005	0.995	0.000
T40.6 Other and unspecified narcotics	0.005	0.995	0.000
E10.2 With renal complications	0.000	0.995	0.005
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.005	0.995	0.000
T40.8 Lysergide [LSD]	0.005	0.995	0.000
T40.7 Cannabis (derivatives)	0.005	0.995	0.000
T40.5 Cocaine	0.005	0.995	0.000
T40.3 Methadone	0.005	0.995	0.000
T40.1 Heroin	0.005	0.995	0.000
T40.0 Opium	0.005	0.995	0.000
N27 Small kidney of unknown cause	0.005	0.995	0.000
N93.0 Postcoital and contact bleeding	0.000	0.995	0.005
N26 Unspecified contracted kidney	0.005	0.995	0.000
D52.8 Other folate deficiency anaemias	0.004	0.995	0.000
D52.1 Drug-induced folate deficiency anaemia	0.004	0.995	0.000
D52.0 Dietary folate deficiency anaemia	0.004	0.995	0.000
M22.3 Other derangements of patella	0.004	0.995	0.000
E10.7 With multiple complications	0.000	0.995	0.004
N29.1 Other disorders of kidney and ureter in infectious and parasitic diseases classified elsewhere	0.004	0.995	0.000
N29.0 Late syphilis of kidney	0.004	0.995	0.000
K35.9 Acute appendicitis, unspecified	0.000	0.995	0.005
N25.8 Other disorders resulting from impaired renal tubular function	0.004	0.995	0.000
N25.9 Disorder resulting from impaired renal tubular function, unspecified	0.004	0.996	0.000
E10.6 With other specified complications	0.000	0.996	0.004
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.004	0.996	0.000
D53 Other nutritional anaemias	0.004	0.996	0.000
N25.1 Nephrogenic diabetes insipidus	0.004	0.996	0.000
N25.0 Renal osteodystrophy	0.004	0.996	0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis	0.000	0.996	0.004
J35.1 Hypertrophy of tonsils	0.004	0.996	0.000
H36 Retinal disorders in diseases classified elsewhere	0.000	0.996	0.004
M22.10 Recurrent subluxation of patella, unspecified knee	0.004	0.996	0.000
D73.0 Hyposplenism	0.000	0.996	0.004
E10.8 With unspecified complications	0.000	0.996	0.004
J35.2 Hypertrophy of adenoids	0.004	0.996	0.000
J35.3 Hypertrophy of tonsils with hypertrophy of adenoids	0.004	0.996	0.000
H35.3 Degeneration of macula and posterior pole	0.000	0.996	0.004
E10.1 With ketoacidosis	0.000	0.996	0.004
N27.9 Small kidney, unspecified	0.003	0.996	0.000
N27.0 Small kidney, unilateral	0.003	0.996	0.000
Z00.5 Examination of potential donor of organ and tissue	0.000	0.996	0.004
H35 Other retinal disorders	0.000	0.996	0.004
E10.9 Without complications	0.000	0.996	0.004
N27.1 Small kidney, bilateral	0.003	0.996	0.000
J35.9 Chronic disease of tonsils and adenoids, unspecified	0.003	0.996	0.000
D53.9 Nutritional anaemia, unspecified	0.003	0.997	0.000
E14.3 With ophthalmic complications	0.000	0.997	0.003
H35.4 Peripheral retinal degeneration	0.000	0.997	0.003
D53.8 Other specified nutritional anaemias	0.003	0.997	0.000
D53.2 Scorbutic anaemia	0.003	0.997	0.000
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.003	0.997	0.000
D53.0 Protein deficiency anaemia	0.003	0.997	0.000
G24.9 Dystonia, unspecified	0.003	0.997	0.000
N39.4 Other specified urinary incontinence	0.000	0.997	0.003
N94.1 Dyspareunia	0.000	0.997	0.003
H35.5 Hereditary retinal dystrophy	0.000	0.997	0.003
Z00.8 Other general examinations	0.000	0.997	0.003
Z00.3 Examination for adolescent development state	0.000	0.997	0.003
Z00.2 Examination for period of rapid growth in childhood	0.000	0.997	0.003
Z00.1 Routine child health examination	0.000	0.997	0.003
M23.6 Other spontaneous disruption of ligament(s) of knee	0.003	0.997	0.000
S61.7 Multiple open wounds of wrist and hand	0.003	0.997	0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.003	0.997	0.000
H18.5 Hereditary corneal dystrophies	0.000	0.997	0.003
H36.8 Other retinal disorders in diseases classified elsewhere	0.000	0.997	0.003
H35.9 Retinal disorder, unspecified	0.000	0.997	0.003
B25.9 Cytomegaloviral disease, unspecified	0.003	0.997	0.000
H35.2 Other proliferative retinopathy	0.000	0.997	0.003
M23.30 Other meniscus derangements (Multiple sites)	0.003	0.997	0.000
H35.8 Other specified retinal disorders	0.000	0.997	0.003
Z00.4 General psychiatric examination, not elsewhere classified	0.000	0.997	0.003
Z00.6 Examination for normal comparison and control in clinical research programme	0.000	0.997	0.003
Y83.8 Other surgical procedures	0.003	0.997	0.000
H35.1 Retinopathy of prematurity	0.000	0.997	0.003
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.003	0.997	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.003	0.997	0.000
H35.7 Separation of retinal layers	0.000	0.997	0.003
M62.81 Other specified disorders of muscle (Shoulder region)	0.003	0.997	0.000
M72.27 Plantar fascial fibromatosis-Ankle/Foot	0.003	0.997	0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)	0.003	0.997	0.000
D46.9 Myelodysplastic syndrome, unspecified	0.003	0.997	0.000
M23.46 Loose body in knee-O/unsp lat men	0.003	0.997	0.000
M23.69 Other spontaneous disruption of ligament(s) of knee (Unspecified ligament or Unspecified meniscus)	0.002	0.997	0.000
M23.67 Other spontaneous disruption of ligament(s) of knee (Capsular ligament)	0.002	0.997	0.000
M23.66 Other spontaneous disruption of ligament(s) of knee-O/unsp	0.002	0.997	0.000
M23.65 Other spontaneous disruption of ligament(s) of knee-Pst hrn	0.002	0.997	0.000
M23.64 Other spontaneous disruption of ligament(s) of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.002	0.997	0.000
M23.63 Other spontaneous disruption of ligament(s) of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.002	0.997	0.000
M23.62 Other spontaneous disruption of ligament(s) of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.002	0.997	0.000
M23.60 Other spontaneous disruption of ligament(s) of knee (Multiple sites)	0.002	0.997	0.000
M23.3 Other meniscus derangements	0.003	0.997	0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.003	0.997	0.000
M62.8 Other specified disorders of muscle	0.003	0.997	0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.003	0.997	0.000
E14 Unspecified diabetes mellitus	0.000	0.997	0.003
S61.8 Open wound of other parts of wrist and hand	0.003	0.997	0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.002	0.998	0.000
K25.7 Chronic without haemorrhage or perforation	0.002	0.998	0.000
M62.51 Muscle wasting and atrophy, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
M23 Internal derangement of knee	0.002	0.998	0.000
M35.0 Sicca syndrome [Sjogren]	0.002	0.998	0.000
R60 Oedema, not elsewhere classified	0.000	0.998	0.002
H35.6 Retinal haemorrhage	0.000	0.998	0.002
M62.80 Other specified disorders of muscle (Multiple sites)	0.002	0.998	0.000
M62 Other disorders of muscle	0.002	0.998	0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.002	0.998	0.000
M31.3 Wegener's granulomatosis	0.002	0.998	0.000
M62.84 Other specified disorders of muscle (Hand)	0.002	0.998	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.002	0.998	0.000
M62.54 Muscle wasting and atrophy, not elsewhere classified (Hand)	0.002	0.998	0.000
M62.89 Other specified disorders of muscle (Site unspecified)	0.002	0.998	0.000
H35.0 Background retinopathy and retinal vascular changes	0.000	0.998	0.002
M23.4 Loose body in knee	0.002	0.998	0.000
M62.83 Other specified disorders of muscle (Forearm)	0.002	0.998	0.000
E10-E14 Diabetes mellitus	0.000	0.998	0.002
S93.1 Dislocation of toe(s)	0.002	0.998	0.000
M62.1 Other rupture of muscle (nontraumatic)	0.002	0.998	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.002	0.998	0.000
M23.37 Other meniscus derangements-Capsular lig	0.002	0.998	0.000
M62.87 Other specified disorders of muscle (Ankle and foot)	0.002	0.998	0.000
M20-M25 Other joint disorders	0.002	0.998	0.000
M72.2 Plantar fascial fibromatosis	0.002	0.998	0.000
M62.11 Other rupture of muscle (nontraumatic) (Shoulder region)	0.002	0.998	0.000
M23.0 Cystic meniscus	0.002	0.998	0.000
E14.8 With unspecified complications	0.000	0.998	0.002
E14.7 With multiple complications	0.000	0.998	0.002
E14.6 With other specified complications	0.000	0.998	0.002
E14.5 With peripheral circulatory complications	0.000	0.998	0.002
E14.2 Withrenal complications	0.000	0.998	0.002
E14.1 With ketoacidosis	0.000	0.998	0.002
E14.0 With coma	0.000	0.998	0.002
M72.0 Palmar fascial fibromatosis [Dupuytren]	0.002	0.998	0.000
N97.9 Female infertility, unspecified	0.002	0.998	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.002	0.998	0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
K09.0 Developmental odontogenic cysts	0.002	0.998	0.000
M31 Other necrotising vasculopathies	0.002	0.998	0.000
M62.59 Muscle wasting and atrophy, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
M62.58 Muscle wasting and atrophy, not elsewhere classified (Other)	0.002	0.998	0.000
M62.57 Muscle wasting and atrophy, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
M62.56 Muscle wasting and atrophy, not elsewhere classified (Lower leg)	0.002	0.998	0.000
M62.55 Muscle wasting and atrophy, not elsewhere classified (Pelvic region and thigh)	0.002	0.998	0.000
M62.53 Muscle wasting and atrophy, not elsewhere classified (Forearm)	0.002	0.998	0.000
M62.52 Muscle wasting and atrophy, not elsewhere classified (Upper arm)	0.002	0.998	0.000
M62.50 Muscle wasting and atrophy, not elsewhere classified (Multiple sites)	0.002	0.998	0.000
M35 Other systemic involvement of connective tissue	0.002	0.998	0.000
H30-H36 Disorders of choroid and retina	0.000	0.998	0.002
M23.5 Chronic instability of knee	0.002	0.998	0.000
O70.0 First degree perineal laceration during delivery	0.002	0.998	0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.000	0.998	0.002
K81.9 Cholecystitis, unspecified	0.002	0.998	0.000
M23.1 Discoid meniscus (congenital)	0.002	0.998	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
E14.9 Without complications	0.000	0.998	0.002
M34 Systemic sclerosis	0.002	0.998	0.000
M23.9 Internal derangement of knee, unspecified	0.002	0.998	0.000
M62.9 Disorder of muscle, unspecified	0.002	0.998	0.000
M62.6 Muscle strain	0.002	0.998	0.000
M62.4 Contracture of muscle	0.002	0.998	0.000
M62.3 Immobility syndrome (paraplegic)	0.002	0.998	0.000
M62.2 Ischaemic infarction of muscle	0.002	0.998	0.000
M62.0 Diastasis of muscle	0.002	0.998	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.002	0.998	0.000
M62.82 Other specified disorders of muscle (Upper arm)	0.002	0.998	0.000
H11.4 Other conjunctival vascular disorders and cysts	0.000	0.998	0.002
N81.5 Vaginal enterocele	0.002	0.998	0.000
T46.1 Calcium-channel blockers	0.002	0.998	0.000
M30 Polyarteritis nodosa and related conditions	0.002	0.998	0.000
M23.47 Loose body in knee-Capsular lig	0.002	0.998	0.000
M23.45 Loose body in knee-Pst hrn lat men	0.002	0.998	0.000
M23.44 Loose body in knee-Lat lig/ant men	0.002	0.998	0.000
M23.42 Loose body in knee-Pst lig/hrn men	0.002	0.998	0.000
M23.41 Loose body in knee-Ant lig/hrn men	0.002	0.998	0.000
M23.40 Loose body in knee-Mult sites	0.002	0.998	0.000
M62.88 Other specified disorders of muscle (Other)	0.002	0.998	0.000
A63.0 Anogenital (venereal) warts	0.002	0.998	0.000
M23.06 Cystic meniscus (Other and unspecified lateral meniscus)	0.002	0.998	0.000
D46.7 Other myelodysplastic syndromes	0.002	0.998	0.000
D46 Myelodysplastic syndromes	0.002	0.998	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.002	0.998	0.000
E27.8 Other specified disorders of adrenal gland	0.002	0.998	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.002	0.998	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.002	0.998	0.000
Z11.2 Special screening examination for other bacterial diseases	0.002	0.998	0.000
E12 Malnutrition-related diabetes mellitus	0.000	0.998	0.002
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M23.03 Cystic meniscus (Medial collateral ligament or Other and unspecified medial meniscus)	0.002	0.998	0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.002	0.998	0.000
M62.19 Other rupture of muscle (nontraumatic) (Site unspecified)	0.002	0.998	0.000
M62.18 Other rupture of muscle (nontraumatic) (Other)	0.002	0.998	0.000
M62.17 Other rupture of muscle (nontraumatic) (Ankle and foot)	0.002	0.998	0.000
M62.16 Other rupture of muscle (nontraumatic) (Lower leg)	0.002	0.998	0.000
M62.15 Other rupture of muscle (nontraumatic) (Pelvic region and thigh)	0.002	0.998	0.000
M62.14 Other rupture of muscle (nontraumatic) (Hand)	0.002	0.998	0.000
M62.13 Other rupture of muscle (nontraumatic) (Forearm)	0.002	0.998	0.000
M62.12 Other rupture of muscle (nontraumatic) (Upper arm)	0.002	0.998	0.000
M62.10 Other rupture of muscle (nontraumatic) (Multiple sites)	0.002	0.998	0.000
J32.0 Chronic maxillary sinusitis	0.002	0.998	0.000
M33 Dermatopolymyositis	0.002	0.998	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.002	0.998	0.000
M30.0 Polyarteritis nodosa	0.002	0.998	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.002	0.998	0.000
M31.0 Hypersensitivity angiitis	0.002	0.998	0.000
M35.8 Other specified systemic involvement of connective tissue	0.002	0.998	0.000
M35.1 Other overlap syndromes	0.002	0.998	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.002	0.998	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.002	0.998	0.000
T46.7 Peripheral vasodilators	0.002	0.998	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.002	0.998	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.002	0.998	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.002	0.998	0.000
M62.86 Other specified disorders of muscle (Lower leg)	0.002	0.998	0.000
M72.29 Plantar fascial fibromatosis-Site unspec	0.002	0.998	0.000
M72.28 Plantar fascial fibromatosis-Other	0.002	0.998	0.000
M72.26 Plantar fascial fibromatosis-Lower Leg	0.002	0.998	0.000
M72.25 Plantar fascial fibromatosis-Pelvic/Thigh	0.002	0.998	0.000
M72.24 Plantar fascial fibromatosis-Hand	0.002	0.998	0.000
M72.23 Plantar fascial fibromatosis-Forearm	0.002	0.998	0.000
M72.22 Plantar fascial fibromatosis-Upper arm	0.002	0.998	0.000
M72.21 Plantar fascial fibromatosis-Shldr region	0.002	0.998	0.000
M72.20 Plantar fascial fibromatosis-Mult sites	0.002	0.998	0.000
F05.9 Delirium, unspecified	0.000	0.998	0.002
H18 Other disorders of cornea	0.000	0.998	0.002
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.002	0.998	0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.002	0.998	0.000
M34.9 Systemic sclerosis, unspecified	0.002	0.998	0.000
M23.07 Cystic meniscus-Capsular lig	0.002	0.998	0.000
M23.05 Cystic meniscus (Posterior horn of lateral meniscus)	0.002	0.998	0.000
M23.04 Cystic meniscus (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.002	0.998	0.000
M23.02 Cystic meniscus (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.002	0.998	0.000
M23.01 Cystic meniscus (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.002	0.998	0.000
M23.00 Cystic meniscus (Multiple sites)	0.002	0.998	0.000
M72.08 Palmar fascial fibromatosis [Dupuytren]-Other	0.002	0.998	0.000
M72.07 Palmar fascial fibromatosis [Dupuytren]-Ankle/Foot	0.002	0.998	0.000
M72.06 Palmar fascial fibromatosis [Dupuytren]-Lower Leg	0.002	0.998	0.000
M72.05 Palmar fascial fibromatosis [Dupuytren]-Pelvic/Thigh	0.002	0.998	0.000
M72.03 Palmar fascial fibromatosis [Dupuytren]-Forearm	0.002	0.998	0.000
M72.02 Palmar fascial fibromatosis [Dupuytren]-Upper arm	0.002	0.998	0.000
M72.01 Palmar fascial fibromatosis [Dupuytren]-Shldr region	0.002	0.998	0.000
M72.00 Palmar fascial fibromatosis [Dupuytren]-Mult sites	0.002	0.998	0.000
K62.0 Anal polyp	0.002	0.998	0.000
M35.7 Hypermobility syndrome	0.002	0.998	0.000
D46.2 Refractory anaemia with excess of blasts	0.002	0.998	0.000
K57.3 Diverticular disease of large intestine without perforation or abscess	0.000	0.998	0.002
M35.2 Behcet's disease	0.002	0.998	0.000
T36 Poisoning by systemic antibiotics	0.002	0.998	0.000
M23.43 Loose body in knee-Med lig/oth men	0.002	0.998	0.000
M31.9 Necrotising vasculopathy, unspecified	0.002	0.998	0.000
M31.8 Other specified necrotising vasculopathies	0.002	0.998	0.000
M31.7 Microscopic polyangiitis	0.002	0.998	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.002	0.998	0.000
M31.2 Lethal midline granuloma	0.002	0.998	0.000
M31.1 Thrombotic microangiopathy	0.002	0.998	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.002	0.998	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.002	0.998	0.000
M35.5 Multifocal fibrosclerosis	0.002	0.998	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.002	0.998	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.000	0.998	0.002
M32 Systemic lupus erythematosus	0.002	0.998	0.000
M23.57 Chronic instability of knee (Capsular ligament)	0.002	0.998	0.000
M23.56 Chronic instability of knee (Other and unspecified lateral meniscus)	0.002	0.998	0.000
M23.55 Chronic instability of knee (Posterior horn of lateral meniscus)	0.002	0.998	0.000
M23.54 Chronic instability of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.002	0.998	0.000
M23.53 Chronic instability of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.002	0.998	0.000
M23.52 Chronic instability of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.002	0.998	0.000
M23.50 Chronic instability of knee (Multiple sites)	0.002	0.998	0.000
M72.09 Palmar fascial fibromatosis [Dupuytren]-Site unspec	0.002	0.998	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.002	0.998	0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.000	0.998	0.002
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.002	0.998	0.000
Z11.0 Special screening examination for intestinal infectious diseases	0.002	0.998	0.000
M23.93 Internal derangement of knee, unspecified (Medial collateral ligament or Other and unspecified medial meniscus)	0.002	0.998	0.000
H18.8 Other specified disorders of cornea	0.000	0.998	0.002
M34.8 Other forms of systemic sclerosis	0.002	0.998	0.000
M23.19 Discoid meniscus (congenital) (Unspecified ligament or Unspecified meniscus)	0.001	0.998	0.000
M23.17 Discoid meniscus (congenital)-Capsular lig	0.001	0.998	0.000
M23.15 Discoid meniscus (congenital) (Posterior horn of lateral meniscus)	0.001	0.998	0.000
M23.14 Discoid meniscus (congenital) (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.001	0.998	0.000
M23.13 Discoid meniscus (congenital) (Medial collateral ligament or Other and unspecified medial meniscus)	0.001	0.998	0.000
M23.12 Discoid meniscus (congenital) (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.001	0.998	0.000
M23.11 Discoid meniscus (congenital) (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.001	0.998	0.000
M23.10 Discoid meniscus (congenital) (Multiple sites)	0.001	0.998	0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.000	0.998	0.002
F20.0 Paranoid schizophrenia	0.000	0.998	0.002
K70.0 Alcoholic fatty liver	0.000	0.998	0.002
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.002	0.998	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.002	0.998	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.002	0.998	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.002	0.998	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.002	0.998	0.000
T44.0 Anticholinesterase agents	0.002	0.998	0.000
M72 Fibroblastic disorders	0.002	0.998	0.000
M23.97 Internal derangement of knee, unspecified (Capsular ligament)	0.001	0.998	0.000
M23.96 Internal derangement of knee, unspecified (Other and unspecified lateral meniscus)	0.001	0.998	0.000
M23.95 Internal derangement of knee, unspecified (Posterior horn of lateral meniscus)	0.001	0.998	0.000
M23.94 Internal derangement of knee, unspecified (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.001	0.998	0.000
M23.92 Internal derangement of knee, unspecified (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.001	0.998	0.000
M23.91 Internal derangement of knee, unspecified (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.001	0.998	0.000
M23.90 Internal derangement of knee, unspecified (Multiple sites)	0.001	0.998	0.000
S22.40 Multiple fractures of ribs (closed)	0.000	0.998	0.002
E14.4 With neurological complications	0.000	0.998	0.001
I50.9 Heart failure, unspecified	0.002	0.998	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.002	0.998	0.000
M34.0 Progressive systemic sclerosis	0.002	0.998	0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.002	0.998	0.000
S93.0 Dislocation of ankle joint	0.002	0.998	0.000
Z96.8 Presence of other specified functional implants	0.000	0.998	0.002
H30 Chorioretinal inflammation	0.000	0.998	0.002
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.002	0.998	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.002	0.998	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.002	0.998	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.002	0.998	0.000
M23.09 Cystic meniscus (Unspecified ligament or Unspecified meniscus)	0.001	0.998	0.000
M23.16 Discoid meniscus (congenital) (Other and unspecified lateral meniscus)	0.002	0.998	0.000
M62.09 Diastasis of muscle (Site unspecified)	0.001	0.998	0.000
M62.08 Diastasis of muscle (Other)	0.001	0.998	0.000
M62.07 Diastasis of muscle (Ankle and foot)	0.001	0.998	0.000
M62.06 Diastasis of muscle (Lower leg)	0.001	0.998	0.000
M62.05 Diastasis of muscle (Pelvic region and thigh)	0.001	0.998	0.000
M62.04 Diastasis of muscle (Hand)	0.001	0.998	0.000
M62.03 Diastasis of muscle (Forearm)	0.001	0.998	0.000
M62.02 Diastasis of muscle (Upper arm)	0.001	0.998	0.000
M62.01 Diastasis of muscle (Shoulder region)	0.001	0.998	0.000
M62.00 Diastasis of muscle (Multiple sites)	0.001	0.998	0.000
M62.29 Ischaemic infarction of muscle (Site unspecified)	0.001	0.998	0.000
M62.28 Ischaemic infarction of muscle (Other)	0.001	0.998	0.000
M62.27 Ischaemic infarction of muscle (Ankle and foot)	0.001	0.998	0.000
M62.26 Ischaemic infarction of muscle (Lower leg)	0.001	0.998	0.000
M62.25 Ischaemic infarction of muscle (Pelvic region and thigh)	0.001	0.998	0.000
M62.24 Ischaemic infarction of muscle (Hand)	0.001	0.998	0.000
M62.23 Ischaemic infarction of muscle (Forearm)	0.001	0.998	0.000
M62.22 Ischaemic infarction of muscle (Upper arm)	0.001	0.998	0.000
M62.21 Ischaemic infarction of muscle (Shoulder region)	0.001	0.998	0.000
M62.20 Ischaemic infarction of muscle (Multiple sites)	0.001	0.998	0.000
M62.39 Immobility syndrome (paraplegic) (Site unspecified)	0.001	0.998	0.000
M62.38 Immobility syndrome (paraplegic) (Other)	0.001	0.998	0.000
M62.37 Immobility syndrome (paraplegic) (Ankle and foot)	0.001	0.998	0.000
M62.36 Immobility syndrome (paraplegic) (Lower leg)	0.001	0.998	0.000
M62.35 Immobility syndrome (paraplegic) (Pelvic region and thigh)	0.001	0.998	0.000
M62.34 Immobility syndrome (paraplegic) (Hand)	0.001	0.998	0.000
M62.33 Immobility syndrome (paraplegic) (Forearm)	0.001	0.998	0.000
M62.32 Immobility syndrome (paraplegic) (Upper arm)	0.001	0.998	0.000
M62.31 Immobility syndrome (paraplegic) (Shoulder region)	0.001	0.998	0.000
M62.30 Immobility syndrome (paraplegic) (Multiple sites)	0.001	0.998	0.000
M62.49 Contracture of muscle (Site unspecified)	0.001	0.998	0.000
M62.48 Contracture of muscle (Other)	0.001	0.998	0.000
M62.47 Contracture of muscle (Ankle and foot)	0.001	0.998	0.000
M62.46 Contracture of muscle (Lower leg)	0.001	0.998	0.000
M62.45 Contracture of muscle (Pelvic region and thigh)	0.001	0.998	0.000
M62.44 Contracture of muscle (Hand)	0.001	0.998	0.000
M62.43 Contracture of muscle (Forearm)	0.001	0.998	0.000
M62.42 Contracture of muscle (Upper arm)	0.001	0.998	0.000
M62.41 Contracture of muscle (Shoulder region)	0.001	0.998	0.000
M62.40 Contracture of muscle (Multiple sites)	0.001	0.998	0.000
M62.69 Muscle strain (Site unspecified)	0.001	0.998	0.000
M62.68 Muscle strain (Other)	0.001	0.998	0.000
M62.67 Muscle strain (Ankle and foot)	0.001	0.998	0.000
M62.66 Muscle strain (Lower leg)	0.001	0.998	0.000
M62.65 Muscle strain (Pelvic region and thigh)	0.001	0.998	0.000
M62.64 Muscle strain (Hand)	0.001	0.998	0.000
M62.63 Muscle strain (Forearm)	0.001	0.998	0.000
M62.62 Muscle strain (Upper arm)	0.001	0.998	0.000
M62.61 Muscle strain (Shoulder region)	0.001	0.998	0.000
M62.60 Muscle strain (Multiple sites)	0.001	0.998	0.000
M62.99 Disorder of muscle, unspecified (Site unspecified)	0.001	0.998	0.000
M62.98 Disorder of muscle, unspecified (Other)	0.001	0.998	0.000
M62.97 Disorder of muscle, unspecified (Ankle and foot)	0.001	0.998	0.000
M62.96 Disorder of muscle, unspecified (Lower leg)	0.001	0.998	0.000
M62.95 Disorder of muscle, unspecified (Pelvic region and thigh)	0.001	0.998	0.000
M62.94 Disorder of muscle, unspecified (Hand)	0.001	0.998	0.000
M62.93 Disorder of muscle, unspecified (Forearm)	0.001	0.998	0.000
M62.92 Disorder of muscle, unspecified (Upper arm)	0.001	0.998	0.000
M62.91 Disorder of muscle, unspecified (Shoulder region)	0.001	0.998	0.000
M62.90 Disorder of muscle, unspecified (Multiple sites)	0.001	0.998	0.000
M34.1 CR(E)ST syndrome	0.002	0.998	0.000
R60.1 Generalised oedema	0.001	0.998	0.001
M30.8 Other conditions related to polyarteritis nodosa	0.001	0.998	0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.001	0.998	0.000
M30.2 Juvenile polyarteritis	0.001	0.998	0.000
M33.1 Other dermatomyositis	0.002	0.998	0.000
W25.9 Unspecified place	0.002	0.998	0.000
M23.59 Chronic instability of knee (Unspecified ligament or Unspecified meniscus)	0.001	0.998	0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
M84.48 Pathological fracture, not elsewhere classified (Other)	0.002	0.998	0.000
H18.9 Disorder of cornea, unspecified	0.000	0.998	0.002
R84.5 Abnormal microbiological findings	0.002	0.998	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.002	0.998	0.000
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality	0.001	0.998	0.000
D46.5 Refractory anaemia with multi-lineage dysplasia	0.001	0.998	0.000
D46.4 Refractory anaemia, unspecified	0.001	0.998	0.000
D46.3 Refractory anaemia with excess of blasts with transformation	0.001	0.998	0.000
D46.1 Refractory anaemia with sideroblasts	0.001	0.998	0.000
D46.0 Refractory anaemia without sideroblasts, so stated	0.001	0.998	0.000
H18.1 Bullous keratopathy	0.000	0.998	0.002
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere	0.001	0.998	0.000
M36.3 Arthropathy in other blood disorders	0.001	0.998	0.000
M36.2 Haemophilic arthropathy	0.001	0.998	0.000
M36.1 Arthropathy in neoplastic disease	0.001	0.998	0.000
M36.0 Dermato(poly)myositis in neoplastic disease	0.001	0.998	0.000
T36.0 Penicillins	0.002	0.998	0.000
T38.1 Thyroid hormones and substitutes	0.001	0.998	0.000
X63.0 Home	0.002	0.998	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.002	0.998	0.000
M24.26 Disorder of ligament (Lower leg)	0.002	0.998	0.000
E12.9 Without complications	0.000	0.998	0.001
E12.8 With unspecified complications	0.000	0.998	0.001
E12.7 With multiple complications	0.000	0.998	0.001
E12.6 With other specified complications	0.000	0.998	0.001
E12.5 With peripheral circulatory complications	0.000	0.998	0.001
E12.4 With neurological complications	0.000	0.998	0.001
E12.3 With ophthalmic complications	0.000	0.998	0.001
E12.2 With renal complications	0.000	0.998	0.001
E12.1 With ketoacidosis	0.000	0.998	0.001
E12.0 With coma	0.000	0.998	0.001
M33.9 Dermatopolymyositis, unspecified	0.001	0.998	0.000
M33.0 Juvenile dermatomyositis	0.001	0.998	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.001	0.998	0.000
M23.49 Loose body in knee-Unspec lig/men	0.002	0.998	0.000
I33.0 Acute and subacute infective endocarditis	0.000	0.998	0.002
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.000	0.998	0.002
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
T38.9 Other and unspecified hormone antagonists	0.001	0.998	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.001	0.998	0.000
T38.7 Androgens and anabolic congeners	0.001	0.998	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.001	0.998	0.000
T38.5 Other oestrogens and progestogens	0.001	0.998	0.000
T38.4 Oral contraceptives	0.001	0.998	0.000
T38.2 Antithyroid drugs	0.001	0.998	0.000
T38.0 Glucocorticoids and synthetic analogues	0.001	0.998	0.000
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)	0.001	0.998	0.000
M33.2 Polymyositis	0.001	0.998	0.000
H31 Other disorders of choroid	0.000	0.998	0.001
C45.9 Mesothelioma, unspecified	0.002	0.998	0.000
H18.7 Other corneal deformities	0.000	0.998	0.001
H18.3 Changes in corneal membranes	0.000	0.998	0.001
H18.0 Corneal pigmentations and deposits	0.000	0.998	0.001
M24.5 Contracture of joint	0.002	0.998	0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.001	0.998	0.000
B25 Cytomegaloviral disease	0.001	0.998	0.000
E13 Other specified diabetes mellitus	0.000	0.998	0.001
T36.9 Systemic antibiotic, unspecified	0.001	0.998	0.000
T36.8 Other systemic antibiotics	0.001	0.998	0.000
T36.7 Antifungal antibiotics, systemically used	0.001	0.998	0.000
T36.6 Rifamycins	0.001	0.998	0.000
T36.5 Aminoglycosides	0.001	0.998	0.000
T36.4 Tetracyclines	0.001	0.998	0.000
T36.3 Macrolides	0.001	0.998	0.000
T36.2 Chloramphenicol group	0.001	0.998	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.001	0.998	0.000
C65 Malignant neoplasm of renal pelvis	0.002	0.998	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.001	0.998	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations