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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs11073333
log Bayes Factor = 10.1344
Chromosome 15   position 38,820,647  (GRCh37) Explore rs11073333 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E03 Other hypothyroidism
0.993 0.007 0.000
E00-E07 Disorders of thyroid gland
0.988 0.012 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.977 0.023 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.970 0.030 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.970 0.030 0.000
M20-M25 Other joint disorders
0.957 0.043 0.000
M86-M90 Other osteopathies
0.956 0.044 0.000
E05.9 Thyrotoxicosis, unspecified
0.953 0.047 0.000
E50-E64 Other nutritional deficiencies
0.950 0.050 0.000
M40-M43 Deforming dorsopathies
0.948 0.052 0.000
M43 Other deforming dorsopathies
0.939 0.061 0.000
E53 Deficiency of other B group vitamins
0.931 0.069 0.000
M89 Other disorders of bone
0.931 0.069 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.926 0.074 0.000
M43.1 Spondylolisthesis
0.924 0.076 0.000
E53.8 Deficiency of other specified B group vitamins
0.919 0.081 0.000
M31 Other necrotising vasculopathies
0.917 0.083 0.000
M43.17 Spondylolisthesis (Lumbosacral region)
0.911 0.089 0.000
M89.8 Other specified disorders of bone
0.906 0.094 0.000
# Top node
0.893 0.107 0.000
D86 Sarcoidosis
0.891 0.109 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.890 0.110 0.000
M21 Other acquired deformities of limbs
0.885 0.115 0.000
D80-D89 Certain disorders involving the immune mechanism
0.880 0.120 0.000
M80-M85 Disorders of bone density and structure
0.880 0.120 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.877 0.123 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.877 0.123 0.000
Chapter XX External causes of morbidity and mortality
0.874 0.126 0.000
D86.9 Sarcoidosis, unspecified
0.867 0.133 0.000
M31.3 Wegener's granulomatosis
0.862 0.138 0.000
M60-M63 Disorders of muscles
0.855 0.145 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.852 0.148 0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified
0.849 0.151 0.000
M22 Disorders of patella
0.841 0.159 0.000
D86.1 Sarcoidosis of lymph nodes
0.840 0.160 0.000
M35 Other systemic involvement of connective tissue
0.838 0.162 0.000
D86.0 Sarcoidosis of lung
0.835 0.165 0.000
W50-W64 Exposure to animate mechanical forces
0.833 0.167 0.000
M87 Osteonecrosis
0.830 0.169 0.000
M05-M14 Inflammatory polyarthropathies
0.826 0.174 0.000
M84 Disorders of continuity of bone
0.825 0.175 0.000
E61 Deficiency of other nutrient elements
0.824 0.176 0.000
M25 Other joint disorders, not elsewhere classified
0.819 0.181 0.000
M21.1 Varus deformity, not elsewhere classified
0.817 0.183 0.000
V40-V49 Car occupant injured in transport accident
0.811 0.189 0.000
M89.85 Other specified disorders of bone (Pelvic region and thigh)
0.808 0.192 0.000
Y85 Sequelae of transport accidents
0.806 0.194 0.000
M30 Polyarteritis nodosa and related conditions
0.805 0.195 0.000
W55 Bitten or struck by other mammals
0.803 0.197 0.000
M31.1 Thrombotic microangiopathy
0.801 0.199 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.797 0.203 0.000
D86.8 Sarcoidosis of other and combined sites
0.790 0.210 0.000
M43.0 Spondylolysis
0.788 0.212 0.000
M06 Other rheumatoid arthritis
0.786 0.214 0.000
M35.0 Sicca syndrome [Sjogren]
0.786 0.214 0.000
W55.0 Home
0.786 0.214 0.000
M62 Other disorders of muscle
0.783 0.217 0.000
M89.86 Other specified disorders of bone (Lower leg)
0.775 0.225 0.000
E03.8 Other specified hypothyroidism
0.774 0.226 0.000
M89.83 Other specified disorders of bone (Forearm)
0.772 0.228 0.000
M25.7 Osteophyte
0.770 0.230 0.000
M06.9 Rheumatoid arthritis, unspecified
0.770 0.230 0.000
M45-M49 Spondylopathies
0.770 0.230 0.000
E10-E14 Diabetes mellitus
0.769 0.231 0.000
E03.1 Congenital hypothyroidism without goitre
0.765 0.235 0.000
M89.4 Other hypertrophic osteo-arthropathy
0.762 0.238 0.000
E20-E35 Disorders of other endocrine glands
0.758 0.242 0.000
M25.71 Osteophyte (Shoulder region)
0.757 0.243 0.000
M84.0 Malunion of fracture
0.757 0.243 0.000
X20-X29 Contact with venomous animals and plants
0.754 0.246 0.000
Y86 Sequelae of other accidents
0.751 0.249 0.000
M31.7 Microscopic polyangiitis
0.750 0.250 0.000
M89.81 Other specified disorders of bone (Shoulder region)
0.749 0.251 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.749 0.251 0.000
M96.0 Pseudarthrosis after fusion or arthrodesis
0.746 0.254 0.000
Y85.0 Sequelae of motor-vehicle accident
0.743 0.257 0.000
E05.8 Other thyrotoxicosis
0.740 0.260 0.000
D50-D53 Nutritional anaemias
0.740 0.260 0.000
M89.0 Algoneurodystrophy
0.739 0.260 0.000
M84.03 Malunion of fracture (Forearm)
0.739 0.261 0.000
M43.19 Spondylolisthesis (Site unspecified)
0.738 0.262 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.738 0.262 0.000
M48 Other spondylopathies
0.737 0.263 0.000
M25.3 Other instability of joint
0.731 0.269 0.000
M65-M68 Disorders of synovium and tendon
0.729 0.271 0.000
E54 Ascorbic acid deficiency
0.729 0.271 0.000
V10-V19 Pedal cyclist injured in transport accident
0.728 0.272 0.000
M22.2 Patellofemoral disorders
0.728 0.272 0.000
M43.8 Other specified deforming dorsopathies
0.728 0.272 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.725 0.275 0.000
D51 Vitamin B12 deficiency anaemia
0.724 0.276 0.000
Chapter VI Diseases of the nervous system
0.723 0.277 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.722 0.278 0.000
M86 Osteomyelitis
0.721 0.279 0.000
G30-G32 Other degenerative diseases of the nervous system
0.721 0.279 0.000
M21.6 Other acquired deformities of ankle and foot
0.719 0.281 0.000
M88 Paget's disease of bone [osteitis deformans]
0.719 0.281 0.000
M34 Systemic sclerosis
0.719 0.281 0.000
M62.8 Other specified disorders of muscle
0.716 0.284 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.716 0.284 0.000
E29 Testicular dysfunction
0.716 0.284 0.000
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)
0.713 0.287 0.000
E03.5 Myxoedema coma
0.712 0.288 0.000
E03.4 Atrophy of thyroid (acquired)
0.712 0.288 0.000
E03.3 Postinfectious hypothyroidism
0.712 0.288 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.712 0.288 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.708 0.292 0.000
E00 Congenital iodine-deficiency syndrome
0.708 0.292 0.000
G30 Alzheimer's disease
0.708 0.292 0.000
M80 Osteoporosis with pathological fracture
0.708 0.292 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.707 0.293 0.000
M43.16 Spondylolisthesis (Lumbar region)
0.707 0.293 0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)
0.707 0.293 0.000
M00-M03 Infectious arthropathies
0.707 0.293 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.707 0.293 0.000
Y00-Y09 Assault
0.705 0.295 0.000
M43.02 Spondylolysis (Cervical region)
0.702 0.298 0.000
M33 Dermatopolymyositis
0.702 0.298 0.000
Chapter XXII Codes for special purposes
0.701 0.299 0.000
E05.5 Thyroid crisis or storm
0.701 0.299 0.000
E05.4 Thyrotoxicosis factitia
0.701 0.299 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.701 0.299 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.701 0.299 0.000
E61.1 Iron deficiency
0.700 0.300 0.000
G30.9 Alzheimer's disease, unspecified
0.698 0.302 0.000
M25.37 Other instability of joint (Ankle and foot)
0.692 0.308 0.000
E51 Thiamine deficiency
0.692 0.308 0.000
V48 Car occupant injured in noncollision transport accident
0.690 0.310 0.000
M48.0 Spinal stenosis
0.688 0.312 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.688 0.312 0.000
M85 Other disorders of bone density and structure
0.688 0.312 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.687 0.313 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.687 0.313 0.000
M22.0 Recurrent dislocation of patella
0.686 0.314 0.000
Y85.9 Sequelae of other and unspecified transport accidents
0.686 0.314 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.686 0.314 0.000
E29.1 Testicular hypofunction
0.685 0.315 0.000
V49 Car occupant injured in other and unspecified transport accidents
0.683 0.317 0.000
M87.9 Osteonecrosis, unspecified
0.682 0.318 0.000
M99 Biomechanical lesions, not elsewhere classified
0.681 0.318 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.681 0.319 0.000
E63 Other nutritional deficiencies
0.681 0.319 0.000
E56 Other vitamin deficiencies
0.681 0.319 0.000
E50 Vitamin A deficiency
0.681 0.319 0.000
E60 Dietary zinc deficiency
0.681 0.319 0.000
E59 Dietary selenium deficiency
0.681 0.319 0.000
E58 Dietary calcium deficiency
0.681 0.319 0.000
E52 Niacin deficiency [pellagra]
0.681 0.319 0.000
M21.7 Unequal limb length (acquired)
0.680 0.320 0.000
M25.78 Osteophyte (Other)
0.680 0.320 0.000
D84 Other immunodeficiencies
0.680 0.320 0.000
E11 Non-insulin-dependent diabetes mellitus
0.680 0.320 0.000
M42 Spinal osteochondrosis
0.679 0.320 0.000
M25.9 Joint disorder, unspecified
0.676 0.324 0.000
M43.9 Deforming dorsopathy, unspecified
0.673 0.327 0.000
M43.5 Other recurrent vertebral subluxation
0.673 0.327 0.000
M43.4 Other recurrent atlantoaxial subluxation
0.673 0.327 0.000
M43.3 Recurrent atlantoaxial subluxation with myelopathy
0.673 0.327 0.000
M43.2 Other fusion of spine
0.673 0.327 0.000
Chapter V Mental and behavioural disorders
0.672 0.328 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.672 0.328 0.000
M96.8 Other postprocedural musculoskeletal disorders
0.671 0.329 0.000
M89.88 Other specified disorders of bone (Other)
0.668 0.332 0.000
X23 Contact with hornets, wasps and bees
0.668 0.332 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.668 0.332 0.000
E53.1 Pyridoxine deficiency
0.668 0.332 0.000
E53.0 Riboflavin deficiency
0.668 0.332 0.000
M89.6 Osteopathy after poliomyelitis
0.668 0.332 0.000
M89.2 Other disorders of bone development and growth
0.668 0.332 0.000
M89.1 Epiphyseal arrest
0.668 0.332 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.667 0.333 0.000
Y89 Sequelae of other external causes
0.667 0.333 0.000
M43.6 Torticollis
0.666 0.334 0.000
W75-W84 Other accidental threats to breathing
0.666 0.334 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.665 0.335 0.000
M43.18 Spondylolisthesis (Sacral and sacrococcygeal region)
0.663 0.337 0.000
M43.15 Spondylolisthesis (Thoracolumbar region)
0.663 0.337 0.000
M43.14 Spondylolisthesis (Thoracic region)
0.663 0.337 0.000
M43.13 Spondylolisthesis (Cervicothoracic region)
0.663 0.337 0.000
M43.11 Spondylolisthesis (Occipito-atlanto-axial region)
0.663 0.337 0.000
M43.10 Spondylolisthesis (Multiple sites in spine)
0.663 0.337 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.661 0.339 0.000
M87.0 Idiopathic aseptic necrosis of bone
0.661 0.339 0.000
Q25 Congenital malformations of great arteries
0.661 0.339 0.000
M30.0 Polyarteritis nodosa
0.660 0.340 0.000
Y10-Y34 Event of undetermined intent
0.660 0.340 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.660 0.340 0.000
D86.3 Sarcoidosis of skin
0.658 0.341 0.000
M83 Adult osteomalacia
0.658 0.342 0.000
M31.9 Necrotising vasculopathy, unspecified
0.658 0.342 0.000
M31.8 Other specified necrotising vasculopathies
0.658 0.342 0.000
M31.4 Aortic arch syndrome [Takayasu]
0.658 0.342 0.000
M31.2 Lethal midline granuloma
0.658 0.342 0.000
M31.0 Hypersensitivity angiitis
0.658 0.342 0.000
M89.5 Osteolysis
0.656 0.344 0.000
M87.8 Other osteonecrosis
0.654 0.346 0.000
E61.2 Magnesium deficiency
0.653 0.347 0.000
E70-E90 Metabolic disorders
0.653 0.347 0.000
M06.4 Inflammatory polyarthropathy
0.652 0.348 0.000
M89.84 Other specified disorders of bone (Hand)
0.652 0.348 0.000
M84.3 Stress fracture, not elsewhere classified
0.652 0.348 0.000
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)
0.651 0.349 0.000
W64 Exposure to other and unspecified animate mechanical forces
0.651 0.349 0.000
M25.4 Effusion of joint
0.651 0.349 0.000
M89.89 Other specified disorders of bone (Site unspecified)
0.650 0.350 0.000
M89.82 Other specified disorders of bone (Upper arm)
0.650 0.350 0.000
M89.80 Other specified disorders of bone (Multiple sites)
0.650 0.350 0.000
E11.9 Without complications
0.650 0.350 0.000
M84.8 Other disorders of continuity of bone
0.649 0.351 0.000
V01-V09 Pedestrian injured in transport accident
0.648 0.352 0.000
V95-V97 Air and space transport accidents
0.648 0.352 0.000
M13 Other arthritis
0.648 0.352 0.000
M25.72 Osteophyte (Upper arm)
0.647 0.353 0.000
V19 Pedal cyclist injured in other and unspecified transport accidents
0.647 0.353 0.000
M12 Other specific arthropathies
0.647 0.353 0.000
Q76 Congenital malformations of spine and bony thorax
0.645 0.355 0.000
M22.8 Other disorders of patella
0.645 0.355 0.000
G62 Other polyneuropathies
0.644 0.356 0.000
E85 Amyloidosis
0.643 0.357 0.000
M21.9 Acquired deformity of limb, unspecified
0.642 0.358 0.000
E11.1 With ketoacidosis
0.641 0.359 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.640 0.360 0.000
M89.40 Other hypertrophic osteoarthropathy (Multiple sites)
0.640 0.360 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.639 0.361 0.000
M96.6 Fracture of bone following insertion of orthopaedic implant, joint prosthesis or bone plate
0.638 0.362 0.000
M96.5 Postradiation scoliosis
0.638 0.362 0.000
M96.4 Postsurgical lordosis
0.638 0.362 0.000
M96.3 Postlaminectomy kyphosis
0.638 0.362 0.000
M96.2 Postradiation kyphosis
0.638 0.362 0.000
D60-D64 Aplastic and other anaemias
0.637 0.363 0.000
M35.3 Polymyalgia rheumatica
0.637 0.363 0.000
V70-V79 Bus occupant injured in transport accident
0.636 0.364 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.635 0.365 0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.634 0.366 0.000
M21.8 Other specified acquired deformities of limbs
0.634 0.366 0.000
V98-V99 Other and unspecified transport accidents
0.633 0.367 0.000
M22.3 Other derangements of patella
0.633 0.367 0.000
D82 Immunodeficiency associated with other major defects
0.631 0.369 0.000
D81 Combined immunodeficiencies
0.631 0.369 0.000
M40 Kyphosis and lordosis
0.631 0.369 0.000
F00 Dementia in Alzheimer's disease
0.630 0.370 0.000
M90 Osteopathies in diseases classified elsewhere
0.629 0.371 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.628 0.372 0.000
M65 Synovitis and tenosynovitis
0.628 0.372 0.000
E53.9 Vitamin B deficiency, unspecified
0.627 0.373 0.000
Y35-Y36 Legal intervention and operations of war
0.626 0.374 0.000
X85-X99 Assault
0.626 0.374 0.000
X30-X39 Exposure to forces of nature
0.626 0.374 0.000
W65-W74 Accidental drowning and submersion
0.626 0.374 0.000
V90-V94 Water transport accidents
0.626 0.374 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.626 0.374 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.626 0.374 0.000
Q00-Q07 Congenital malformations of the nervous system
0.625 0.375 0.000
M91-M94 Chondropathies
0.624 0.375 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.624 0.376 0.000
V43 Car occupant injured in collision with car, pick-up truck or van
0.623 0.377 0.000
M21.3 Wrist or foot drop (acquired)
0.623 0.377 0.000
G70-G73 Diseases of myoneural junction and muscle
0.622 0.378 0.000
G62.9 Polyneuropathy, unspecified
0.622 0.378 0.000
V44 Car occupant injured in collision with heavy transport vehicle or bus
0.622 0.378 0.000
D61 Other aplastic anaemias
0.621 0.379 0.000
M62.89 Other specified disorders of muscle (Site unspecified)
0.618 0.382 0.000
M62.80 Other specified disorders of muscle (Multiple sites)
0.618 0.382 0.000
M22.9 Disorder of patella, unspecified
0.618 0.382 0.000
V11 Pedal cyclist injured in collision with other pedal cycle
0.617 0.383 0.000
E26 Hyperaldosteronism
0.616 0.384 0.000
M89.9 Disorder of bone, unspecified
0.616 0.384 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.616 0.384 0.000
E34 Other endocrine disorders
0.615 0.385 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.615 0.385 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.614 0.386 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.613 0.387 0.000
M61 Calcification and ossification of muscle
0.613 0.387 0.000
G60 Hereditary and idiopathic neuropathy
0.613 0.387 0.000
E14 Unspecified diabetes mellitus
0.613 0.387 0.000
E85.4 Organ-limited amyloidosis
0.611 0.389 0.000
D61.9 Aplastic anaemia, unspecified
0.611 0.389 0.000
Chapter VIII Diseases of the ear and mastoid process
0.611 0.389 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.611 0.389 0.000
M89.3 Hypertrophy of bone
0.609 0.390 0.000
W50 Hit, struck, kicked, twisted, bitten or scratched by another person
0.608 0.391 0.000
M80.0 Postmenopausal osteoporosis with pathological fracture
0.608 0.392 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.608 0.392 0.000
G31.2 Degeneration of nervous system due to alcohol
0.607 0.393 0.000
V20-V29 Motorcycle rider injured in transport accident
0.606 0.394 0.000
F01 Vascular dementia
0.605 0.395 0.000
E06 Thyroiditis
0.605 0.395 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.605 0.395 0.000
X00-X09 Exposure to smoke, fire and flames
0.603 0.396 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.603 0.397 0.000
M22.1 Recurrent subluxation of patella
0.603 0.397 0.000
Q35-Q37 Cleft lip and cleft palate
0.602 0.398 0.000
M32 Systemic lupus erythematosus
0.601 0.398 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.601 0.399 0.000
M35.8 Other specified systemic involvement of connective tissue
0.601 0.399 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.601 0.399 0.000
M35.5 Multifocal fibrosclerosis
0.601 0.399 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.601 0.399 0.000
M21.67 Other acquired deformities of ankle and foot-Ankle/foot
0.601 0.399 0.000
Q60-Q64 Congenital malformations of the urinary system
0.600 0.400 0.000
M62.9 Disorder of muscle, unspecified
0.600 0.400 0.000
M89.87 Other specified disorders of bone (Ankle and foot)
0.600 0.400 0.000
F00.9 Dementia in Alzheimer's disease, unspecified
0.600 0.400 0.000
Y88 Sequelae of surgical and medical care as external cause
0.599 0.401 0.000
D83 Common variable immunodeficiency
0.599 0.401 0.000
W51 Striking against or bumped into by another person
0.599 0.401 0.000
M21.2 Flexion deformity
0.597 0.403 0.000
W59 Bitten or crushed by other reptiles
0.597 0.403 0.000
W58 Bitten or struck by crocodile or alligator
0.597 0.403 0.000
W56 Contact with marine animal
0.597 0.403 0.000
W54 Bitten or struck by dog
0.597 0.403 0.000
W53 Bitten by rat
0.597 0.403 0.000
W52 Crushed, pushed and stepped on by crowd or human stampede
0.597 0.403 0.000
X59 Exposure to unspecified factor
0.596 0.404 0.000
M49 Spondylopathies in diseases classified elsewhere
0.596 0.404 0.000
M87.3 Other secondary osteonecrosis
0.595 0.404 0.000
M87.1 Osteonecrosis due to drugs
0.595 0.404 0.000
Q76.0 Spina bifida occulta
0.595 0.405 0.000
Y52 Agents primarily affecting the cardiovascular system
0.595 0.405 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.593 0.407 0.000
E20 Hypoparathyroidism
0.593 0.407 0.000
E65-E68 Obesity and other hyperalimentation
0.593 0.407 0.000
M84.01 Malunion of fracture (Shoulder region)
0.593 0.407 0.000
E28 Ovarian dysfunction
0.593 0.407 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.592 0.407 0.000
M08 Juvenile arthritis
0.592 0.407 0.000
M84.9 Disorder of continuity of bone, unspecified
0.592 0.408 0.000
M84.2 Delayed union of fracture
0.592 0.408 0.000
E61.9 Deficiency of nutrient element, unspecified
0.591 0.409 0.000
E61.8 Deficiency of other specified nutrient elements
0.591 0.409 0.000
E61.7 Deficiency of multiple nutrient elements
0.591 0.409 0.000
E61.6 Vanadium deficiency
0.591 0.409 0.000
E61.5 Molybdenum deficiency
0.591 0.409 0.000
E61.4 Chromium deficiency
0.591 0.409 0.000
E61.3 Manganese deficiency
0.591 0.409 0.000
E61.0 Copper deficiency
0.591 0.409 0.000
M84.02 Malunion of fracture (Upper arm)
0.589 0.411 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.589 0.411 0.000
Q23 Congenital malformations of aortic and mitral valves
0.587 0.413 0.000
M25.2 Flail joint
0.587 0.413 0.000
M25.1 Fistula of joint
0.587 0.413 0.000
M21.19 Varus deformity, not elsewhere classified (Site unspecified)
0.585 0.414 0.000
M21.18 Varus deformity, not elsewhere classified (Other)
0.585 0.414 0.000
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)
0.585 0.414 0.000
M21.14 Varus deformity, not elsewhere classified (Hand)
0.585 0.414 0.000
M21.13 Varus deformity, not elsewhere classified (Forearm)
0.585 0.414 0.000
M21.12 Varus deformity, not elsewhere classified (Upper arm)
0.585 0.414 0.000
M21.11 Varus deformity, not elsewhere classified (Shoulder region)
0.585 0.414 0.000
M21.10 Varus deformity, not elsewhere classified (Multiple sites)
0.585 0.414 0.000
M85.6 Other cyst of bone
0.585 0.415 0.000
X23.0 Home
0.584 0.415 0.000
E11.0 With coma
0.583 0.417 0.000
M86.6 Other chronic osteomyelitis
0.583 0.417 0.000
F52 Sexual dysfunction, not caused by organic disorder or disease
0.582 0.418 0.000
M34.1 CR(E)ST syndrome
0.582 0.418 0.000
V47 Car occupant injured in collision with fixed or stationary object
0.581 0.419 0.000
V46 Car occupant injured in collision with other nonmotor vehicle
0.581 0.419 0.000
V45 Car occupant injured in collision with railway train or railway vehicle
0.581 0.419 0.000
V42 Car occupant injured in collision with two- or three-wheeled motor vehicle
0.581 0.419 0.000
V41 Car occupant injured in collision with pedal cycle
0.581 0.419 0.000
V40 Car occupant injured in collision with pedestrian or animal
0.581 0.419 0.000
M60 Myositis
0.581 0.419 0.000
Q25.1 Coarctation of aorta
0.581 0.419 0.000
M43.12 Spondylolisthesis (Cervical region)
0.581 0.419 0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.580 0.420 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.580 0.420 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.580 0.420 0.000
M48.8 Other specified spondylopathies
0.580 0.420 0.000
M30.8 Other conditions related to polyarteritis nodosa
0.577 0.423 0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]
0.577 0.423 0.000
M30.2 Juvenile polyarteritis
0.577 0.423 0.000
M43.86 Other specified deforming dorsopathies (Lumbar region)
0.577 0.423 0.000
W55.9 Unspecified place
0.576 0.424 0.000
W55.5 Trade and service area
0.576 0.424 0.000
W55.7 Farm
0.576 0.424 0.000
W55.6 Industrial and construction area
0.576 0.424 0.000
W55.4 Street and highway
0.576 0.424 0.000
W55.3 Sports and athletics area
0.576 0.424 0.000
W55.2 School, other institution and public administrative area
0.576 0.424 0.000
W55.1 Residential institution
0.576 0.424 0.000
M21.4 Flat foot [pes planus] (acquired)
0.576 0.424 0.000
M87.98 Osteonecrosis, unspecified (Other)
0.576 0.424 0.000
V48.6 Passenger injured in traffic accident
0.576 0.424 0.000
M25.94 Joint disorder, unspecified (Hand)
0.575 0.425 0.000
M96.9 Postprocedural musculoskeletal disorder, unspecified
0.575 0.425 0.000
M48.09 Spinal stenosis (Site unspecified)
0.575 0.425 0.000
V19.3 Pedal cyclist [any] injured in an unspecified nontraffic accident
0.574 0.426 0.000
X10-X19 Contact with heat and hot substances
0.573 0.427 0.000
M43.09 Spondylolysis (Site unspecified)
0.572 0.428 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.572 0.428 0.000
M62.6 Muscle strain
0.570 0.430 0.000
M87.2 Osteonecrosis due to previous trauma
0.569 0.431 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.569 0.431 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.569 0.431 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.568 0.432 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.568 0.432 0.000
M35.7 Hypermobility syndrome
0.568 0.432 0.000
F60-F69 Disorders of adult personality and behaviour
0.568 0.432 0.000
M89.07 Algoneurodystrophy (Ankle and foot)
0.567 0.433 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.567 0.433 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.567 0.433 0.000
M48.02 Spinal stenosis (Cervical region)
0.566 0.434 0.000
F03 Unspecified dementia
0.565 0.435 0.000
M43.08 Spondylolysis (Sacral and sacrococcygeal region)
0.565 0.435 0.000
M43.07 Spondylolysis (Lumbosacral region)
0.565 0.435 0.000
M43.05 Spondylolysis (Thoracolumbar region)
0.565 0.435 0.000
M43.04 Spondylolysis (Thoracic region)
0.565 0.435 0.000
M43.03 Spondylolysis (Cervicothoracic region)
0.565 0.435 0.000
M43.01 Spondylolysis (Occipito-atlanto-axial region)
0.565 0.435 0.000
M43.00 Spondylolysis (Multiple sites in spine)
0.565 0.435 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.564 0.436 0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified
0.564 0.436 0.000
M06.8 Other specified rheumatoid arthritis
0.564 0.436 0.000
M06.2 Rheumatoid bursitis
0.564 0.436 0.000
M06.1 Adult-onset Still's disease
0.564 0.436 0.000
M62.83 Other specified disorders of muscle (Forearm)
0.563 0.437 0.000
M25.31 Other instability of joint (Shoulder region)
0.563 0.437 0.000
M62.4 Contracture of muscle
0.561 0.439 0.000
M62.3 Immobility syndrome (paraplegic)
0.561 0.439 0.000
M62.2 Ischaemic infarction of muscle
0.561 0.439 0.000
M62.1 Other rupture of muscle (nontraumatic)
0.561 0.439 0.000
M62.0 Diastasis of muscle
0.561 0.439 0.000
W60 Contact with plant thorns and spines and sharp leaves
0.561 0.439 0.000
M13.0 Polyarthritis, unspecified
0.561 0.439 0.000
M84.4 Pathological fracture, not elsewhere classified
0.560 0.440 0.000
M35.2 Behcet's disease
0.560 0.440 0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)
0.560 0.440 0.000
E22 Hyperfunction of pituitary gland
0.560 0.440 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.558 0.441 0.000
M95.2 Other acquired deformity of head
0.558 0.442 0.000
Q78 Other osteochondrodysplasias
0.558 0.442 0.000
W57 Bitten or stung by non-venomous insect and other non-venomous arthropods
0.558 0.442 0.000
Q25.4 Other congenital malformations of aorta
0.558 0.442 0.000
Y04 Assault by bodily force
0.558 0.442 0.000
E85.9 Amyloidosis, unspecified
0.558 0.442 0.000
M41 Scoliosis
0.557 0.443 0.000
X58 Exposure to other specified factors
0.557 0.443 0.000
M24 Other specific joint derangements
0.557 0.443 0.000
M89.04 Algoneurodystrophy (Hand)
0.556 0.444 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.555 0.445 0.000
M85.4 Solitary bone cyst
0.555 0.445 0.000
M46 Other inflammatory spondylopathies
0.554 0.446 0.000
M25.79 Osteophyte (Site unspecified)
0.553 0.447 0.000
M62.88 Other specified disorders of muscle (Other)
0.553 0.447 0.000
M25.73 Osteophyte (Forearm)
0.552 0.447 0.000
M25.70 Osteophyte (Multiple sites)
0.552 0.447 0.000
E07 Other disorders of thyroid
0.552 0.448 0.000
M62.82 Other specified disorders of muscle (Upper arm)
0.552 0.448 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.552 0.448 0.000
E12 Malnutrition-related diabetes mellitus
0.551 0.449 0.000
M86.4 Chronic osteomyelitis with draining sinus
0.551 0.449 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.551 0.449 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.551 0.449 0.000
M86.8 Other osteomyelitis
0.550 0.450 0.000
M88.9 Paget's disease of bone, unspecified
0.550 0.450 0.000
M14 Arthropathies in other diseases classified elsewhere
0.548 0.452 0.000
G30.1 Alzheimer's disease with late onset
0.548 0.452 0.000
E34.9 Endocrine disorder, unspecified
0.548 0.452 0.000
M89.49 Other hypertrophic osteoarthropathy (Site unspecified)
0.546 0.454 0.000
M89.48 Other hypertrophic osteoarthropathy (Other)
0.546 0.454 0.000
M89.47 Other hypertrophic osteoarthropathy (Ankle and foot)
0.546 0.454 0.000
M89.46 Other hypertrophic osteoarthropathy (Lower leg)
0.546 0.454 0.000
M89.45 Other hypertrophic osteoarthropathy (Pelvic region and thigh)
0.546 0.454 0.000
M89.44 Other hypertrophic osteoarthropathy (Hand)
0.546 0.454 0.000
M89.43 Other hypertrophic osteoarthropathy (Forearm)
0.546 0.454 0.000
M89.42 Other hypertrophic osteoarthropathy (Upper arm)
0.546 0.454 0.000
M89.41 Other hypertrophic osteoarthropathy (Shoulder region)
0.546 0.454 0.000
E85.3 Secondary systemic amyloidosis
0.546 0.454 0.000
M05 Seropositive rheumatoid arthritis
0.546 0.454 0.000
E14.3 With ophthalmic complications
0.545 0.455 0.000
M89.09 Algoneurodystrophy (Site unspecified)
0.544 0.456 0.000
V09 Pedestrian injured in other and unspecified transport accidents
0.544 0.456 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.544 0.456 0.000
E32 Diseases of thymus
0.544 0.456 0.000
E31 Polyglandular dysfunction
0.544 0.456 0.000
E30 Disorders of puberty, not elsewhere classified
0.544 0.456 0.000
E25 Adrenogenital disorders
0.544 0.456 0.000
M48.9 Spondylopathy, unspecified
0.543 0.457 0.000
Q27 Other congenital malformations of peripheral vascular system
0.543 0.457 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.543 0.457 0.000
M84.09 Malunion of fracture (Site unspecified)
0.542 0.457 0.000
M84.08 Malunion of fracture (Other)
0.542 0.457 0.000
M84.00 Malunion of fracture (Multiple sites)
0.542 0.457 0.000
F01.9 Vascular dementia, unspecified
0.542 0.458 0.000
X29 Contact with unspecified venomous animal or plant
0.540 0.459 0.000
X28 Contact with other specified venomous plants
0.540 0.459 0.000
X27 Contact with other specified venomous animals
0.540 0.459 0.000
X26 Contact with venomous marine animals and plants
0.540 0.459 0.000
X25 Contact with other specified venomous arthropods
0.540 0.459 0.000
X24 Contact with centipedes and venomous millipedes (tropical)
0.540 0.459 0.000
X22 Contact with scorpions
0.540 0.459 0.000
X21 Contact with venomous spiders
0.540 0.459 0.000
X20 Contact with venomous snakes and lizards
0.540 0.459 0.000
E28.3 Primary ovarian failure
0.540 0.460 0.000
F52.2 Failure of genital response
0.539 0.461 0.000
M87.05 Idiopathic aseptic necrosis of bone (Pelvic region and thigh)
0.539 0.461 0.000
Q24 Other congenital malformations of heart
0.537 0.462 0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)
0.537 0.463 0.000
M87.91 Osteonecrosis, unspecified (Shoulder region)
0.537 0.463 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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