TreeWAS – Variant ID: rs11121380

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.018	0.982	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.017	0.983	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.017	0.983	0.000
N64.5 Other signs and symptoms in breast	0.016	0.984	0.000
N64 Other disorders of breast	0.016	0.984	0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.016	0.984	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.016	0.984	0.000
I63.8 Other cerebral infarction	0.016	0.984	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.016	0.984	0.000
N63 Unspecified lump in breast	0.016	0.984	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.016	0.984	0.000
I63 Cerebral infarction	0.016	0.984	0.000
O24 Diabetes mellitus in pregnancy	0.015	0.985	0.000
N60-N64 Disorders of breast	0.015	0.985	0.000
O20 Haemorrhage in early pregnancy	0.015	0.985	0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.015	0.985	0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.015	0.985	0.000
O21 Excessive vomiting in pregnancy	0.015	0.985	0.000
O24.4 Diabetes mellitus arising in pregnancy	0.015	0.985	0.000
N64.1 Fat necrosis of breast	0.014	0.986	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.014	0.986	0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.014	0.986	0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.014	0.986	0.000
O47 False labour	0.014	0.986	0.000
O42 Premature rupture of membranes	0.014	0.986	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.014	0.986	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.014	0.986	0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.014	0.986	0.000
O47.1 False labour at or after 37 completed weeks of gestation	0.014	0.986	0.000
O20.0 Threatened abortion	0.014	0.986	0.000
O23 Infections of genito-urinary tract in pregnancy	0.014	0.986	0.000
N60.3 Fibrosclerosis of breast	0.014	0.986	0.000
N60 Benign mammary dysplasia	0.013	0.987	0.000
O85-O92 Complications predominantly related to the puerperium	0.013	0.987	0.000
E83.4 Disorders of magnesium metabolism	0.013	0.987	0.000
O21.0 Mild hyperemesis gravidarum	0.013	0.987	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.013	0.987	0.000
O22 Venous complications in pregnancy	0.013	0.987	0.000
T82.4 Mechanical complication of vascular dialysis catheter	0.013	0.987	0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.013	0.987	0.000
N64.4 Mastodynia	0.012	0.987	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.013	0.987	0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.012	0.987	0.000
O21.9 Vomiting of pregnancy, unspecified	0.012	0.988	0.000
O29 Complications of anaesthesia during pregnancy	0.012	0.988	0.000
O25 Malnutrition in pregnancy	0.012	0.988	0.000
O16 Unspecified maternal hypertension	0.012	0.988	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.012	0.988	0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.012	0.988	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.012	0.988	0.000
N64.3 Galactorrhoea not associated with childbirth	0.012	0.988	0.000
N64.2 Atrophy of breast	0.012	0.988	0.000
N64.0 Fissure and fistula of nipple	0.012	0.988	0.000
O42.9 Premature rupture of membranes, unspecified	0.012	0.988	0.000
O23.9 Other and unspecified genito-urinary tract infection in pregnancy	0.012	0.988	0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.012	0.988	0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.012	0.988	0.000
O97 Death from sequelae of direct obstetric causes	0.012	0.988	0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.012	0.988	0.000
O95 Obstetric death of unspecified cause	0.012	0.988	0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.012	0.988	0.000
O20.8 Other haemorrhage in early pregnancy	0.012	0.988	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.012	0.988	0.000
O46.9 Antepartum haemorrhage, unspecified	0.012	0.988	0.000
N64.9 Disorder of breast, unspecified	0.012	0.988	0.000
N64.8 Other specified disorders of breast	0.012	0.988	0.000
N62 Hypertrophy of breast	0.012	0.988	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.012	0.988	0.000
O20.9 Haemorrhage in early pregnancy, unspecified	0.011	0.988	0.000
O28 Abnormal findings on antenatal screening of mother	0.011	0.989	0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.011	0.989	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.011	0.989	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.011	0.989	0.000
O24.9 Diabetes mellitus in pregnancy, unspecified	0.011	0.989	0.000
O24.3 Pre-existing diabetes mellitus, unspecified	0.011	0.989	0.000
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.011	0.989	0.000
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.011	0.989	0.000
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.011	0.989	0.000
K11 Diseases of salivary glands	0.011	0.989	0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.011	0.989	0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.011	0.989	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.011	0.989	0.000
N60.9 Benign mammary dysplasia, unspecified	0.011	0.989	0.000
N61 Inflammatory disorders of breast	0.011	0.989	0.000
O21.8 Other vomiting complicating pregnancy	0.011	0.989	0.000
O21.2 Late vomiting of pregnancy	0.011	0.989	0.000
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.011	0.989	0.000
O30 Multiple gestation	0.011	0.989	0.000
E83 Disorders of mineral metabolism	0.011	0.989	0.000
O47.9 False labour, unspecified	0.011	0.989	0.000
O90 Complications of the puerperium, not elsewhere classified	0.011	0.989	0.000
I69 Sequelae of cerebrovascular disease	0.011	0.989	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.011	0.989	0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.011	0.989	0.000
I69.3 Sequelae of cerebral infarction	0.011	0.989	0.000
K11.6 Mucocele of salivary gland	0.011	0.989	0.000
O23.4 Unspecified infection of urinary tract in pregnancy	0.011	0.989	0.000
O45 Premature separation of placenta [abruptio placentae]	0.010	0.989	0.000
O33 Maternal care for known or suspected disproportion	0.010	0.989	0.000
O31 Complications specific to multiple gestation	0.010	0.989	0.000
K11.2 Sialoadenitis	0.011	0.989	0.000
O47.0 False labour before 37 completed weeks of gestation	0.010	0.989	0.000
O42.2 Premature rupture of membranes, labour delayed by therapy	0.010	0.990	0.000
K11.5 Sialolithiasis	0.010	0.990	0.000
O15 Eclampsia	0.010	0.990	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.010	0.990	0.000
K29.8 Duodenitis	0.000	0.990	0.010
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.010	0.990	0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.010	0.990	0.000
O86 Other puerperal infections	0.010	0.990	0.000
O87 Venous complications in the puerperium	0.010	0.990	0.000
N60.4 Mammary duct ectasia	0.010	0.990	0.000
O44 Placenta praevia	0.010	0.990	0.000
O23.3 Infections of other parts of urinary tract in pregnancy	0.010	0.990	0.000
O23.2 Infections of urethra in pregnancy	0.010	0.990	0.000
O23.1 Infections of bladder in pregnancy	0.010	0.990	0.000
O23.0 Infections of kidney in pregnancy	0.010	0.990	0.000
N60.2 Fibroadenosis of breast	0.010	0.990	0.000
O22.4 Haemorrhoids in pregnancy	0.010	0.990	0.000
O32.0 Maternal care for unstable lie	0.010	0.990	0.000
N60.0 Solitary cyst of breast	0.010	0.990	0.000
O32.1 Maternal care for breech presentation	0.010	0.990	0.000
O32.2 Maternal care for transverse and oblique lie	0.010	0.990	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.010	0.990	0.000
E21.3 Hyperparathyroidism, unspecified	0.010	0.990	0.000
O92 Other disorders of breast and lactation associated with childbirth	0.010	0.990	0.000
O91 Infections of breast associated with childbirth	0.010	0.990	0.000
O89 Complications of anaesthesia during the puerperium	0.010	0.990	0.000
O88 Obstetric embolism	0.010	0.990	0.000
O85 Puerperal sepsis	0.010	0.990	0.000
W25.9 Unspecified place	0.010	0.990	0.000
E83.5 Disorders of calcium metabolism	0.010	0.990	0.000
O34.8 Maternal care for other abnormalities of pelvic organs	0.010	0.990	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.010	0.990	0.000
O41 Other disorders of amniotic fluid and membranes	0.010	0.990	0.000
E78.0 Pure hypercholesterolaemia	0.010	0.990	0.000
O34.0 Maternal care for congenital malformation of uterus	0.010	0.990	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.010	0.990	0.000
E83.3 Disorders of phosphorus metabolism	0.010	0.990	0.000
O60-O75 Complications of labour and delivery	0.010	0.990	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.010	0.990	0.000
Z35.0 Supervision of pregnancy with history of infertility	0.009	0.990	0.000
O71 Other obstetric trauma	0.009	0.991	0.000
O46.8 Other antepartum haemorrhage	0.009	0.991	0.000
O46.0 Antepartum haemorrhage with coagulation defect	0.009	0.991	0.000
W25 Contact with sharp glass	0.009	0.991	0.000
W20-W49 Exposure to inanimate mechanical forces	0.009	0.991	0.000
O22.9 Venous complication in pregnancy, unspecified	0.009	0.991	0.000
O22.8 Other venous complications in pregnancy	0.009	0.991	0.000
O22.5 Cerebral venous thrombosis in pregnancy	0.009	0.991	0.000
O22.3 Deep phlebothrombosis in pregnancy	0.009	0.991	0.000
O22.2 Superficial thrombophlebitis in pregnancy	0.009	0.991	0.000
O22.1 Genital varices in pregnancy	0.009	0.991	0.000
O22.0 Varicose veins of lower extremity in pregnancy	0.009	0.991	0.000
Z35.5 Supervision of elderly primigravida	0.009	0.991	0.000
O40 Polyhydramnios	0.009	0.991	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.009	0.991	0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.009	0.991	0.000
O32.9 Maternal care for malpresentation of foetus, unspecified	0.009	0.991	0.000
O32.6 Maternal care for compound presentation	0.009	0.991	0.000
O32.3 Maternal care for face, brow and chin presentation	0.009	0.991	0.000
O34.7 Maternal care for abnormality of vulva and perineum	0.009	0.991	0.000
O90.8 Other complications of the puerperium, not elsewhere classified	0.009	0.991	0.000
O43 Placental disorders	0.009	0.991	0.000
K11.1 Hypertrophy of salivary gland	0.009	0.991	0.000
O29.9 Complication of anaesthesia during pregnancy, unspecified	0.009	0.991	0.000
O29.8 Other complications of anaesthesia during pregnancy	0.009	0.991	0.000
O29.6 Failed or difficult intubation during pregnancy	0.009	0.991	0.000
O29.5 Other complications of spinal and epidural anaesthesia during pregnancy	0.009	0.991	0.000
O29.4 Spinal and epidural anaesthesia-induced headache during pregnancy	0.009	0.991	0.000
O29.3 Toxic reaction to local anaesthesia during pregnancy	0.009	0.991	0.000
O29.2 Central nervous system complications of anaesthesia during pregnancy	0.009	0.991	0.000
O29.1 Cardiac complications of anaesthesia during pregnancy	0.009	0.991	0.000
O29.0 Pulmonary complications of anaesthesia during pregnancy	0.009	0.991	0.000
J40 Bronchitis, not specified as acute or chronic	0.009	0.991	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.009	0.991	0.000
O32.4 Maternal care for high head at term	0.009	0.991	0.000
O71.8 Other specified obstetric trauma	0.009	0.991	0.000
Z35 Supervision of high-risk pregnancy	0.009	0.991	0.000
O34.3 Maternal care for cervical incompetence	0.009	0.991	0.000
Y43 Primarily systemic agents	0.009	0.991	0.000
K11.8 Other diseases of salivary glands	0.009	0.991	0.000
T82.3 Mechanical complication of other vascular grafts	0.009	0.991	0.000
O23.5 Infections of the genital tract in pregnancy	0.009	0.991	0.000
O64 Obstructed labour due to malposition and malpresentation of foetus	0.009	0.991	0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.009	0.991	0.000
O96.9 Death from unspecified obstetric cause	0.008	0.991	0.000
O96.1 Death from indirect obstetric cause	0.008	0.991	0.000
O96.0 Death from direct obstetric cause	0.008	0.991	0.000
O97.9 Death from sequelae of obstetric cause, unspecified	0.008	0.991	0.000
O97.1 Death from sequelae of indirect obstetric cause	0.008	0.991	0.000
O97.0 Death from sequelae of direct obstetric cause	0.008	0.991	0.000
O98.9 Unspecified maternal infectious or parasitic disease complicating pregnancy, childbirth and the puerperium	0.008	0.991	0.000
O98.8 Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium	0.008	0.991	0.000
O98.7 Human immunodeficiency [HIV] disease complicating pregnancy, childbirth and the puerperium	0.008	0.991	0.000
O98.6 Protozoal diseases complicating pregnancy, childbirth and the puerperium	0.008	0.991	0.000
O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium	0.008	0.991	0.000
O98.4 Viral hepatitis complicating pregnancy, childbirth and the puerperium	0.008	0.991	0.000
O98.3 Other infections with a predominantly sexual mode of transmission complicating pregnancy, childbirth and the puerperium	0.008	0.991	0.000
O98.2 Gonorrhoea complicating pregnancy, childbirth and the puerperium	0.008	0.991	0.000
O98.1 Syphilis complicating pregnancy, childbirth and the puerperium	0.008	0.991	0.000
O98.0 Tuberculosis complicating pregnancy, childbirth and the puerperium	0.008	0.991	0.000
K11.7 Disturbances of salivary secretion	0.009	0.991	0.000
O14.0 Moderate preeclampsia	0.009	0.991	0.000
W44 Foreign body entering into or through eye or natural orifice	0.009	0.991	0.000
Chapter XX External causes of morbidity and mortality	0.009	0.991	0.000
O34.4 Maternal care for other abnormalities of cervix	0.008	0.991	0.000
O69 Labour and delivery complicated by umbilical cord complications	0.009	0.991	0.000
N18.9 Chronic renal failure, unspecified	0.009	0.991	0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.008	0.991	0.000
O34.6 Maternal care for abnormality of vagina	0.008	0.991	0.000
O34.5 Maternal care for other abnormalities of gravid uterus	0.008	0.991	0.000
I60-I69 Cerebrovascular diseases	0.009	0.991	0.000
N18.5 Chronic kidney disease, stage 5	0.009	0.991	0.000
O86.4 Pyrexia of unknown origin following delivery	0.008	0.992	0.000
O28.9 Abnormal finding on antenatal screening of mother, unspecified	0.008	0.992	0.000
O28.8 Other abnormal findings on antenatal screening of mother	0.008	0.992	0.000
O28.5 Abnormal chromosomal and genetic finding on antenatal screening of mother	0.008	0.992	0.000
O28.4 Abnormal radiological finding on antenatal screening of mother	0.008	0.992	0.000
O28.3 Abnormal ultrasonic finding on antenatal screening of mother	0.008	0.992	0.000
O28.2 Abnormal cytological finding on antenatal screening of mother	0.008	0.992	0.000
O28.0 Abnormal haematological finding on antenatal screening of mother	0.008	0.992	0.000
O30.0 Twin pregnancy	0.008	0.992	0.000
T82.0 Mechanical complication of heart valve prosthesis	0.008	0.992	0.000
K11.9 Disease of salivary gland, unspecified	0.008	0.992	0.000
K11.4 Fistula of salivary gland	0.008	0.992	0.000
K11.3 Abscess of salivary gland	0.008	0.992	0.000
K11.0 Atrophy of salivary gland	0.008	0.992	0.000
O32.8 Maternal care for other malpresentation of foetus	0.008	0.992	0.000
O34.1 Maternal care for tumour of corpus uteri	0.008	0.992	0.000
T82.1 Mechanical complication of cardiac electronic device	0.008	0.992	0.000
O00-O08 Pregnancy with abortive outcome	0.008	0.992	0.000
K12.1 Other forms of stomatitis	0.008	0.992	0.000
E21.0 Primary hyperparathyroidism	0.008	0.992	0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.008	0.992	0.000
N18.0 End-stage renal disease	0.008	0.992	0.000
O71.4 Obstetric high vaginal laceration alone	0.008	0.992	0.000
N18 Chronic renal failure	0.008	0.992	0.000
O72 Postpartum haemorrhage	0.008	0.992	0.000
E87.7 Fluid overload	0.008	0.992	0.000
W44.0 Home	0.008	0.992	0.000
Z35.8 Supervision of other high-risk pregnancies	0.008	0.992	0.000
K12 Stomatitis and related lesions	0.008	0.992	0.000
O30.9 Multiple gestation, unspecified	0.008	0.992	0.000
O30.8 Other multiple gestation	0.008	0.992	0.000
O30.2 Quadruplet pregnancy	0.008	0.992	0.000
O30.1 Triplet pregnancy	0.008	0.992	0.000
O64.1 Obstructed labour due to breech presentation	0.008	0.992	0.000
O87.2 Haemorrhoids in the puerperium	0.008	0.992	0.000
E70-E90 Metabolic disorders	0.008	0.992	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.008	0.992	0.000
E83.8 Other disorders of mineral metabolism	0.008	0.992	0.000
E83.2 Disorders of zinc metabolism	0.008	0.992	0.000
E83.0 Disorders of copper metabolism	0.008	0.992	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.008	0.992	0.000
Y43.1 Antineoplastic antimetabolites	0.008	0.992	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.008	0.992	0.000
O90.9 Complication of the puerperium, unspecified	0.008	0.992	0.000
O90.5 Postpartum thyroiditis	0.008	0.992	0.000
O90.4 Postpartum acute renal failure	0.008	0.992	0.000
O90.3 Cardiomyopathy in the puerperium	0.008	0.992	0.000
O90.2 Haematoma of obstetric wound	0.008	0.992	0.000
O90.1 Disruption of perineal obstetric wound	0.008	0.992	0.000
O90.0 Disruption of Caesarean section wound	0.008	0.992	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.008	0.992	0.000
O14.2 HELLP syndrome	0.008	0.992	0.000
Y44 Agents primarily affecting blood constituents	0.008	0.992	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.008	0.992	0.000
O31.8 Other complications specific to multiple gestation	0.008	0.992	0.000
O31.2 Continuing pregnancy after intra-uterine death of one foetus or more	0.008	0.992	0.000
O31.1 Continuing pregnancy after abortion of one foetus or more	0.008	0.992	0.000
O31.0 Papyraceous foetus	0.008	0.992	0.000
O33.9 Maternal care for disproportion, unspecified	0.008	0.992	0.000
O33.8 Maternal care for disproportion of other origin	0.008	0.992	0.000
O33.7 Maternal care for disproportion due to other foetal deformities	0.008	0.992	0.000
O33.6 Maternal care for disproportion due to hydrocephalic foetus	0.008	0.992	0.000
O33.5 Maternal care for disproportion due to unusually large foetus	0.008	0.992	0.000
O33.4 Maternal care for disproportion of mixed maternal and foetal origin	0.008	0.992	0.000
O33.3 Maternal care for disproportion due to outlet contraction of pelvis	0.008	0.992	0.000
O33.2 Maternal care for disproportion due to inlet contraction of pelvis	0.008	0.992	0.000
O33.1 Maternal care for disproportion due to generally contracted pelvis	0.008	0.992	0.000
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones	0.008	0.992	0.000
O45.9 Premature separation of placenta, unspecified	0.008	0.992	0.000
O45.8 Other premature separation of placenta	0.008	0.992	0.000
O45.0 Premature separation of placenta with coagulation defect	0.008	0.992	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.008	0.992	0.000
I63.9 Cerebral infarction, unspecified	0.008	0.992	0.000
O14.1 Severe preeclampsia	0.008	0.992	0.000
Y43.4 Immunosuppressive agents	0.008	0.992	0.000
O14.9 Preeclampsia, unspecified	0.008	0.992	0.000
O15.9 Eclampsia, unspecified as to time period	0.007	0.992	0.000
O15.2 Eclampsia in the puerperium	0.007	0.992	0.000
O15.1 Eclampsia in labour	0.007	0.992	0.000
O15.0 Eclampsia in pregnancy	0.007	0.992	0.000
O44.1 Placenta praevia with haemorrhage	0.008	0.992	0.000
O86.8 Other specified puerperal infections	0.007	0.992	0.000
O86.3 Other genito-urinary tract infections following delivery	0.007	0.992	0.000
O86.2 Urinary tract infection following delivery	0.007	0.992	0.000
O86.1 Other infection of genital tract following delivery	0.007	0.992	0.000
O72.1 Other immediate postpartum haemorrhage	0.008	0.992	0.000
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.007	0.992	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.008	0.992	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.008	0.992	0.000
K12.3 Oral mucositis (ulcerative)	0.008	0.992	0.000
O87.9 Venous complication in the puerperium, unspecified	0.007	0.992	0.000
O87.8 Other venous complications in the puerperium	0.007	0.992	0.000
O87.3 Cerebral venous thrombosis in the puerperium	0.007	0.992	0.000
O87.1 Deep phlebothrombosis in the puerperium	0.007	0.992	0.000
O87.0 Superficial thrombophlebitis in the puerperium	0.007	0.992	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.008	0.992	0.000
O69.2 Labour and delivery complicated by other cord entanglement	0.007	0.993	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.007	0.993	0.000
O86.0 Infection of obstetric surgical wound	0.007	0.993	0.000
W20 Struck by thrown, projected or falling object	0.007	0.993	0.000
X50-X57 Overexertion, travel and privation	0.007	0.993	0.000
O69.0 Labour and delivery complicated by prolapse of cord	0.007	0.993	0.000
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.007	0.993	0.000
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.007	0.993	0.000
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.007	0.993	0.000
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.007	0.993	0.000
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.007	0.993	0.000
W23 Caught, crushed, jammed or pinched in or between objects	0.007	0.993	0.000
Y42.7 Androgens and anabolic congeners	0.007	0.993	0.000
Y44.5 Thrombolytic drugs	0.007	0.993	0.000
O88.8 Other obstetric embolism	0.007	0.993	0.000
O88.3 Obstetric pyaemic and septic embolism	0.007	0.993	0.000
O88.2 Obstetric blood-clot embolism	0.007	0.993	0.000
O88.1 Amniotic fluid embolism	0.007	0.993	0.000
O88.0 Obstetric air embolism	0.007	0.993	0.000
O89.9 Complication of anaesthesia during the puerperium, unspecified	0.007	0.993	0.000
O89.8 Other complications of anaesthesia during the puerperium	0.007	0.993	0.000
O89.6 Failed or difficult intubation during the puerperium	0.007	0.993	0.000
O89.5 Other complications of spinal and epidural anaesthesia during the puerperium	0.007	0.993	0.000
O89.4 Spinal and epidural anaesthesia-induced headache during the puerperium	0.007	0.993	0.000
O89.3 Toxic reaction to local anaesthesia during the puerperium	0.007	0.993	0.000
O89.2 Central nervous system complications of anaesthesia during the puerperium	0.007	0.993	0.000
O89.1 Cardiac complications of anaesthesia during the puerperium	0.007	0.993	0.000
O89.0 Pulmonary complications of anaesthesia during the puerperium	0.007	0.993	0.000
O91.2 Nonpurulent mastitis associated with childbirth	0.007	0.993	0.000
O91.1 Abscess of breast associated with childbirth	0.007	0.993	0.000
O91.0 Infection of nipple associated with childbirth	0.007	0.993	0.000
O92.7 Other and unspecified disorders of lactation	0.007	0.993	0.000
O92.6 Galactorrhoea	0.007	0.993	0.000
O92.5 Suppressed lactation	0.007	0.993	0.000
O92.4 Hypogalactia	0.007	0.993	0.000
O92.3 Agalactia	0.007	0.993	0.000
O92.2 Other and unspecified disorders of breast associated with childbirth	0.007	0.993	0.000
O92.1 Cracked nipple associated with childbirth	0.007	0.993	0.000
O92.0 Retracted nipple associated with childbirth	0.007	0.993	0.000
O35 Maternal care for known or suspected foetal abnormality and damage	0.007	0.993	0.000
W49 Exposure to other and unspecified inanimate mechanical forces	0.007	0.993	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.007	0.993	0.000
Y00-Y09 Assault	0.007	0.993	0.000
O12.2 Gestational oedema with proteinuria	0.007	0.993	0.000
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.007	0.993	0.000
O41.1 Infection of amniotic sac and membranes	0.007	0.993	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.007	0.993	0.000
V80-V89 Other land transport accidents	0.007	0.993	0.000
O12.1 Gestational proteinuria	0.007	0.993	0.000
V10-V19 Pedal cyclist injured in transport accident	0.007	0.993	0.000
X60-X84 Intentional self-harm	0.007	0.993	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.007	0.993	0.000
Y48 Anaesthetics and therapeutic gases	0.007	0.993	0.000
O41.0 Oligohydramnios	0.007	0.993	0.000
Y59 Other and unspecified vaccines and biological substances	0.007	0.993	0.000
Y58 Bacterial vaccines	0.007	0.993	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.007	0.993	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.007	0.993	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.007	0.993	0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.007	0.993	0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.007	0.993	0.000
O74 Complications of anaesthesia during labour and delivery	0.007	0.993	0.000
O65 Obstructed labour due to maternal pelvic abnormality	0.007	0.993	0.000
O60 Preterm delivery	0.007	0.993	0.000
W21 Striking against or struck by sports equipment	0.007	0.993	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.007	0.993	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.007	0.993	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.007	0.993	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.007	0.993	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.007	0.993	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.007	0.993	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.007	0.993	0.000
Y51.0 Anticholinesterase agents	0.007	0.993	0.000
K12.2 Cellulitis and abscess of mouth	0.007	0.993	0.000
J46 Status asthmaticus	0.007	0.993	0.000
Y40 Systemic antibiotics	0.007	0.993	0.000
O80-O84 Delivery	0.006	0.993	0.001
O71.9 Obstetric trauma, unspecified	0.007	0.993	0.000
O71.7 Obstetric haematoma of pelvis	0.007	0.993	0.000
O71.6 Obstetric damage to pelvic joints and ligaments	0.007	0.993	0.000
O71.5 Other obstetric injury to pelvic organs	0.007	0.993	0.000
O71.3 Obstetric laceration of cervix	0.007	0.993	0.000
O71.2 Postpartum inversion of uterus	0.007	0.993	0.000
O71.1 Rupture of uterus during labour	0.007	0.993	0.000
O71.0 Rupture of uterus before onset of labour	0.007	0.993	0.000
W25.6 Industrial and construction area	0.007	0.993	0.000
W25.5 Trade and service area	0.007	0.993	0.000
W25.1 Residential institution	0.007	0.993	0.000
W25.0 Home	0.007	0.993	0.000
W25.8 Other specified place	0.007	0.993	0.000
W25.7 Farm	0.007	0.993	0.000
W25.4 Street and highway	0.007	0.993	0.000
W25.3 Sports and athletics area	0.007	0.993	0.000
W25.2 School, other institution and public administrative area	0.007	0.993	0.000
W46 Contact with hypodermic needle	0.007	0.993	0.000
W45 Foreign body or object entering through skin	0.007	0.993	0.000
W43 Exposure to vibration	0.007	0.993	0.000
W42 Exposure to noise	0.007	0.993	0.000
W41 Exposure to high-pressure jet	0.007	0.993	0.000
W40 Explosion of other materials	0.007	0.993	0.000
W39 Discharge of firework	0.007	0.993	0.000
W38 Explosion and rupture of other specified pressurised devices	0.007	0.993	0.000
W37 Explosion and rupture of pressurised tyre, pipe or hose	0.007	0.993	0.000
W36 Explosion and rupture of gas cylinder	0.007	0.993	0.000
W35 Explosion and rupture of boiler	0.007	0.993	0.000
W34 Discharge from other and unspecified firearms	0.007	0.993	0.000
W33 Rifle, shotgun and larger firearm discharge	0.007	0.993	0.000
W32 Handgun discharge	0.007	0.993	0.000
W31 Contact with other and unspecified machinery	0.007	0.993	0.000
W30 Contact with agricultural machinery	0.007	0.993	0.000
W28 Contact with powered lawn mower	0.007	0.993	0.000
W27 Contact with nonpowered hand tool	0.007	0.993	0.000
W26 Contact with knife, sword or dagger	0.007	0.993	0.000
W24 Contact with lifting and transmission devices, not elsewhere classified	0.007	0.993	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.007	0.993	0.000
Y43.0 Antiallergic and antiemetic drugs	0.007	0.993	0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.007	0.993	0.000
Y79 Orthopaedic devices associated with adverse incidents	0.007	0.993	0.000
J40-J47 Chronic lower respiratory diseases	0.007	0.993	0.000
Y46.2 Hydantoin derivatives	0.007	0.993	0.000
N60.8 Other benign mammary dysplasias	0.007	0.993	0.000
O44.0 Placenta praevia specified as without haemorrhage	0.007	0.993	0.000
K04.7 Periapical abscess without sinus	0.007	0.993	0.000
V40-V49 Car occupant injured in transport accident	0.007	0.993	0.000
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history	0.007	0.993	0.000
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.007	0.993	0.000
W29 Contact with other powered hand tools and household machinery	0.007	0.993	0.000
O43.9 Placental disorder, unspecified	0.007	0.993	0.000
O43.2 Morbidly adherent placenta	0.007	0.993	0.000
O43.0 Placental transfusion syndromes	0.007	0.993	0.000
O43.8 Other placental disorders	0.007	0.993	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.007	0.993	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.007	0.993	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.007	0.993	0.000
E21.4 Other specified disorders of parathyroid gland	0.007	0.993	0.000
E21.2 Other hyperparathyroidism	0.007	0.993	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.007	0.993	0.000
Y43.9 Primarily systemic agent, unspecified	0.007	0.993	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.007	0.993	0.000
Y43.6 Enzymes, not elsewhere classified	0.007	0.993	0.000
Y43.5 Acidifying and alkalising agents	0.007	0.993	0.000
Y43.2 Antineoplastic natural products	0.007	0.993	0.000
Z35.9 Supervision of high-risk pregnancy, unspecified	0.007	0.993	0.000
Z35.7 Supervision of high-risk pregnancy due to social problems	0.007	0.993	0.000
Z35.6 Supervision of very young primigravida	0.007	0.993	0.000
Z35.4 Supervision of pregnancy with grand multiparity	0.007	0.993	0.000
Z35.3 Supervision of pregnancy with history of insufficient antenatal care	0.007	0.993	0.000
O73 Retained placenta and membranes, without haemorrhage	0.007	0.993	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.007	0.993	0.000
E73 Lactose intolerance	0.007	0.993	0.000
Y57 Other and unspecified drugs and medicaments	0.007	0.993	0.000
Y79.2 Prosthetic and other implants, materials and accessory devices	0.007	0.993	0.000
I60 Subarachnoid haemorrhage	0.007	0.993	0.000
O02 Other abnormal products of conception	0.007	0.993	0.000
O64.9 Obstructed labour due to malposition and malpresentation, unspecified	0.006	0.993	0.000
O64.8 Obstructed labour due to other malposition and malpresentation	0.006	0.993	0.000
O64.5 Obstructed labour due to compound presentation	0.006	0.993	0.000
O64.4 Obstructed labour due to shoulder presentation	0.006	0.993	0.000
O64.3 Obstructed labour due to brow presentation	0.006	0.993	0.000
O64.2 Obstructed labour due to face presentation	0.006	0.993	0.000
O69.1 Labour and delivery complicated by cord around neck, with compression	0.007	0.993	0.000
O26 Maternal care for other conditions predominantly related to pregnancy	0.007	0.993	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.007	0.993	0.000
E87.5 Hyperkalaemia	0.007	0.993	0.000
O12.0 Gestational oedema	0.006	0.993	0.000
E20-E35 Disorders of other endocrine glands	0.007	0.993	0.000
W44.9 Unspecified place	0.006	0.993	0.000
W44.5 Trade and service area	0.006	0.993	0.000
W44.8 Other specified place	0.006	0.993	0.000
W44.7 Farm	0.006	0.993	0.000
W44.6 Industrial and construction area	0.006	0.993	0.000
W44.4 Street and highway	0.006	0.993	0.000
W44.3 Sports and athletics area	0.006	0.993	0.000
W44.2 School, other institution and public administrative area	0.006	0.993	0.000
W44.1 Residential institution	0.006	0.993	0.000
Y35-Y36 Legal intervention and operations of war	0.006	0.993	0.000
Y10-Y34 Event of undetermined intent	0.006	0.993	0.000
X85-X99 Assault	0.006	0.993	0.000
X30-X39 Exposure to forces of nature	0.006	0.993	0.000
X00-X09 Exposure to smoke, fire and flames	0.006	0.993	0.000
W75-W84 Other accidental threats to breathing	0.006	0.993	0.000
W65-W74 Accidental drowning and submersion	0.006	0.993	0.000
V98-V99 Other and unspecified transport accidents	0.006	0.993	0.000
V95-V97 Air and space transport accidents	0.006	0.993	0.000
V90-V94 Water transport accidents	0.006	0.993	0.000
V70-V79 Bus occupant injured in transport accident	0.006	0.993	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.006	0.993	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.006	0.993	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.006	0.993	0.000
V01-V09 Pedestrian injured in transport accident	0.006	0.993	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations