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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs111341849
log Bayes Factor = 13.9983
Chromosome 12   position 83,961,998  (GRCh37) Explore rs111341849 on Ensembl!
Variant rs111341849 is part of Cluster X0064

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
I20-I25 Ischaemic heart diseases
0.999 0.001 0.000
I25 Chronic ischaemic heart disease
0.998 0.002 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.997 0.003 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.996 0.004 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.996 0.004 0.000
E10-E14 Diabetes mellitus
0.995 0.005 0.000
Chapter XX External causes of morbidity and mortality
0.995 0.005 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.994 0.006 0.000
E11 Non-insulin-dependent diabetes mellitus
0.992 0.008 0.000
Chapter VI Diseases of the nervous system
0.992 0.008 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.987 0.013 0.000
I30-I52 Other forms of heart disease
0.984 0.016 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.978 0.022 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.977 0.023 0.000
G40-G47 Episodic and paroxysmal disorders
0.975 0.025 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.975 0.025 0.000
I25.2 Old myocardial infarction
0.975 0.025 0.000
Chapter X Diseases of the respiratory system
0.974 0.026 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.972 0.028 0.000
G43 Migraine
0.969 0.031 0.000
Chapter V Mental and behavioural disorders
0.968 0.032 0.000
G43.9 Migraine, unspecified
0.968 0.032 0.000
E11.3 With ophthalmic complications
0.962 0.038 0.000
S50-S59 Injuries to the elbow and forearm
0.961 0.039 0.000
J95-J99 Other diseases of the respiratory system
0.960 0.040 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.956 0.044 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.955 0.045 0.000
R26 Abnormalities of gait and mobility
0.955 0.045 0.000
R00 Abnormalities of heart beat
0.953 0.047 0.000
I34 Nonrheumatic mitral valve disorders
0.953 0.047 0.000
Chapter I Certain infectious and parasitic diseases
0.951 0.049 0.000
I71 Aortic aneurysm and dissection
0.951 0.049 0.000
I50 Heart failure
0.949 0.051 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.949 0.051 0.000
J98 Other respiratory disorders
0.948 0.052 0.000
E20-E35 Disorders of other endocrine glands
0.947 0.053 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.942 0.058 0.000
R00.0 Tachycardia, unspecified
0.939 0.061 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.936 0.064 0.000
R03.1 Nonspecific low blood-pressure reading
0.929 0.071 0.000
F30-F39 Mood [affective] disorders
0.928 0.072 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.927 0.073 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.925 0.075 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.923 0.077 0.000
I47 Paroxysmal tachycardia
0.921 0.079 0.000
R25 Abnormal involuntary movements
0.920 0.080 0.000
Chapter VII Diseases of the eye and adnexa
0.920 0.080 0.000
I77 Other disorders of arteries and arterioles
0.916 0.084 0.000
S60-S69 Injuries to the wrist and hand
0.913 0.087 0.000
H53-H54 Visual disturbances and blindness
0.909 0.091 0.000
I45 Other conduction disorders
0.908 0.092 0.000
S90-S99 Injuries to the ankle and foot
0.907 0.093 0.000
S51 Open wound of forearm
0.904 0.096 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.904 0.096 0.000
J90-J94 Other diseases of pleura
0.903 0.097 0.000
B25-B34 Other viral diseases
0.902 0.098 0.000
I47.1 Supraventricular tachycardia
0.901 0.099 0.000
I74 Arterial embolism and thrombosis
0.900 0.100 0.000
E11.9 Without complications
0.898 0.102 0.000
J98.4 Other disorders of lung
0.897 0.103 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.896 0.104 0.000
T82.3 Mechanical complication of other vascular grafts
0.896 0.104 0.000
R23 Other skin changes
0.894 0.106 0.000
I34.0 Mitral (valve) insufficiency
0.891 0.109 0.000
I22 Subsequent myocardial infarction
0.890 0.110 0.000
H54 Blindness and low vision
0.889 0.111 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.888 0.112 0.000
J90 Pleural effusion, not elsewhere classified
0.883 0.117 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.878 0.122 0.000
Y52 Agents primarily affecting the cardiovascular system
0.877 0.123 0.000
H10-H13 Disorders of conjunctiva
0.877 0.123 0.000
E00-E07 Disorders of thyroid gland
0.875 0.125 0.000
B34 Viral infection of unspecified site
0.875 0.125 0.000
S70-S79 Injuries to the hip and thigh
0.872 0.128 0.000
G41 Status epilepticus
0.872 0.128 0.000
R06 Abnormalities of breathing
0.869 0.131 0.000
E11.2 With renal complications
0.868 0.132 0.000
E10 Insulin-dependent diabetes mellitus
0.868 0.132 0.000
V80-V89 Other land transport accidents
0.864 0.136 0.000
I50.9 Heart failure, unspecified
0.864 0.136 0.000
G30-G32 Other degenerative diseases of the nervous system
0.863 0.137 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.862 0.138 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.859 0.141 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.858 0.142 0.000
E11.6 With other specified complications
0.857 0.143 0.000
B34.9 Viral infection, unspecified
0.857 0.143 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.856 0.144 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.854 0.146 0.000
I34.1 Mitral (valve) prolapse
0.854 0.146 0.000
I72 Other aneurysm
0.854 0.146 0.000
I50.1 Left ventricular failure
0.853 0.147 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.852 0.148 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.851 0.149 0.000
E70-E90 Metabolic disorders
0.850 0.150 0.000
H11 Other disorders of conjunctiva
0.849 0.151 0.000
Y57 Other and unspecified drugs and medicaments
0.846 0.154 0.000
E83 Disorders of mineral metabolism
0.844 0.156 0.000
E23 Hypofunction and other disorders of pituitary gland
0.843 0.157 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.843 0.157 0.000
R06.8 Other and unspecified abnormalities of breathing
0.843 0.157 0.000
I77.6 Arteritis, unspecified
0.837 0.163 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.835 0.165 0.000
T23 Burn and corrosion of wrist and hand
0.835 0.165 0.000
F31 Bipolar affective disorder
0.834 0.166 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.831 0.169 0.000
I05-I09 Chronic rheumatic heart diseases
0.831 0.169 0.000
Y95 Nosocomial condition
0.830 0.170 0.000
J98.5 Diseases of mediastinum, not elsewhere classified
0.829 0.171 0.000
H54.7 Unspecified visual loss
0.829 0.171 0.000
B35-B49 Mycoses
0.827 0.173 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.824 0.176 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.824 0.176 0.000
F60-F69 Disorders of adult personality and behaviour
0.823 0.177 0.000
S92 Fracture of foot, except ankle
0.822 0.178 0.000
E28 Ovarian dysfunction
0.821 0.179 0.000
J60-J70 Lung diseases due to external agents
0.820 0.180 0.000
S51.9 Open wound of forearm, part unspecified
0.820 0.180 0.000
R25.2 Cramp and spasm
0.820 0.180 0.000
T79-T79 Certain early complications of trauma
0.820 0.180 0.000
Y44 Agents primarily affecting blood constituents
0.819 0.181 0.000
R23.8 Other and unspecified skin changes
0.818 0.182 0.000
S80-S89 Injuries to the knee and lower leg
0.816 0.184 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.816 0.184 0.000
R25.8 Other and unspecified abnormal involuntary movements
0.815 0.185 0.000
E10.9 Without complications
0.815 0.185 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.814 0.185 0.000
J98.8 Other specified respiratory disorders
0.814 0.186 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.814 0.186 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.811 0.189 0.000
X10-X19 Contact with heat and hot substances
0.810 0.190 0.000
R00.2 Palpitations
0.810 0.190 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.809 0.191 0.000
I45.5 Other specified heart block
0.805 0.195 0.000
B50-B64 Protozoal diseases
0.803 0.197 0.000
H53 Visual disturbances
0.803 0.197 0.000
F45 Somatoform disorders
0.802 0.198 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.801 0.198 0.000
E83.5 Disorders of calcium metabolism
0.801 0.199 0.000
H11.3 Conjunctival haemorrhage
0.799 0.201 0.000
R26.3 Immobility
0.799 0.201 0.000
S56 Injury of muscle and tendon at forearm level
0.799 0.201 0.000
S61 Open wound of wrist and hand
0.799 0.201 0.000
R23.1 Pallor
0.798 0.202 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.797 0.203 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.796 0.204 0.000
E22 Hyperfunction of pituitary gland
0.794 0.206 0.000
H54.0 Blindness, both eyes
0.794 0.206 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.792 0.208 0.000
E83.1 Disorders of iron metabolism
0.791 0.209 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.790 0.210 0.000
J98.6 Disorders of diaphragm
0.790 0.210 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.789 0.211 0.000
R23.3 Spontaneous ecchymoses
0.789 0.211 0.000
I25.5 Ischaemic cardiomyopathy
0.788 0.212 0.000
S51.0 Open wound of elbow
0.788 0.212 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.787 0.213 0.000
R79 Other abnormal findings of blood chemistry
0.784 0.216 0.000
R22.4 Localised swelling, mass and lump, lower limb
0.783 0.217 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.783 0.217 0.000
R26.0 Ataxic gait
0.783 0.217 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.782 0.218 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.780 0.220 0.000
H04 Disorders of lachrymal system
0.780 0.220 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.778 0.222 0.000
E04 Other non-toxic goitre
0.778 0.222 0.000
I45.1 Other and unspecified right bundle-branch block
0.777 0.223 0.000
Y45.0 Opioids and related analgesics
0.773 0.227 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.773 0.227 0.000
Chapter XXII Codes for special purposes
0.772 0.228 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.772 0.228 0.000
I20 Angina pectoris
0.770 0.230 0.000
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified
0.770 0.230 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.769 0.231 0.000
E23.7 Disorder of pituitary gland, unspecified
0.768 0.232 0.000
S10-S19 Injuries to the neck
0.767 0.233 0.000
S92.0 Fracture of calcaneus
0.766 0.234 0.000
V40-V49 Car occupant injured in transport accident
0.764 0.236 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.762 0.238 0.000
F45.8 Other somatoform disorders
0.762 0.238 0.000
Y57.9 Drug or medicament, unspecified
0.761 0.239 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.761 0.239 0.000
F32 Depressive episode
0.761 0.239 0.000
E11.8 With unspecified complications
0.759 0.241 0.000
F30 Manic episode
0.759 0.241 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.758 0.242 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.757 0.243 0.000
B37 Candidiasis
0.756 0.244 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.756 0.244 0.000
Y00-Y09 Assault
0.755 0.245 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.755 0.245 0.000
G41.9 Status epilepticus, unspecified
0.753 0.247 0.000
S54 Injury of nerves at forearm level
0.753 0.247 0.000
R26.2 Difficulty in walking, not elsewhere classified
0.753 0.247 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.753 0.247 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.752 0.248 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.751 0.249 0.000
R00.8 Other and unspecified abnormalities of heart beat
0.750 0.250 0.000
E11.1 With ketoacidosis
0.750 0.250 0.000
S70 Superficial injury of hip and thigh
0.749 0.251 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.747 0.253 0.000
G43.8 Other migraine
0.745 0.254 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.745 0.255 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.745 0.255 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.744 0.256 0.000
Q80-Q89 Other congenital malformations
0.744 0.256 0.000
E11.0 With coma
0.743 0.257 0.000
G44 Other headache syndromes
0.742 0.258 0.000
H54.5 Low vision, one eye
0.740 0.260 0.000
I33 Acute and subacute endocarditis
0.740 0.260 0.000
T46.1 Calcium-channel blockers
0.740 0.260 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.740 0.260 0.000
B37.8 Candidiasis of other sites
0.740 0.260 0.000
H53.0 Amblyopia ex anopsia
0.739 0.261 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.739 0.261 0.000
S61.9 Open wound of wrist and hand, part unspecified
0.738 0.262 0.000
I71.0 Dissection of aorta [any part]
0.738 0.262 0.000
F33 Recurrent depressive disorder
0.738 0.262 0.000
I36 Nonrheumatic tricuspid valve disorders
0.737 0.263 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.736 0.264 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.736 0.264 0.000
B99-B99 Other infectious diseases
0.735 0.265 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.735 0.265 0.000
Y46.2 Hydantoin derivatives
0.733 0.267 0.000
G62 Other polyneuropathies
0.733 0.267 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.733 0.267 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.732 0.268 0.000
T23.0 Burn of unspecified degree of wrist and hand
0.730 0.270 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.730 0.270 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.729 0.271 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.727 0.273 0.000
W20-W49 Exposure to inanimate mechanical forces
0.727 0.273 0.000
R82 Other abnormal findings in urine
0.726 0.274 0.000
I50.0 Congestive heart failure
0.726 0.274 0.000
J69 Pneumonitis due to solids and liquids
0.726 0.274 0.000
S50 Superficial injury of forearm
0.725 0.275 0.000
S92.00 Fracture of calcaneus (closed)
0.725 0.275 0.000
F80-F89 Disorders of psychological development
0.724 0.276 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.724 0.276 0.000
X60-X84 Intentional self-harm
0.722 0.277 0.000
W00-W19 Falls
0.722 0.278 0.000
R06.0 Dyspnoea
0.721 0.279 0.000
F60 Specific personality disorders
0.720 0.280 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.719 0.281 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.719 0.281 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.718 0.282 0.000
T86 Failure and rejection of transplanted organs and tissues
0.717 0.283 0.000
G41.0 Grand mal status epilepticus
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.717 0.283 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.716 0.284 0.000
I25.6 Silent myocardial ischaemia
0.716 0.284 0.000
I25.4 Coronary artery aneurysm
0.716 0.284 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.715 0.285 0.000
E07 Other disorders of thyroid
0.714 0.286 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.714 0.286 0.000
E12 Malnutrition-related diabetes mellitus
0.713 0.286 0.000
Y35-Y36 Legal intervention and operations of war
0.713 0.286 0.000
Y10-Y34 Event of undetermined intent
0.713 0.286 0.000
X85-X99 Assault
0.713 0.286 0.000
X30-X39 Exposure to forces of nature
0.713 0.286 0.000
X00-X09 Exposure to smoke, fire and flames
0.713 0.286 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.713 0.286 0.000
W75-W84 Other accidental threats to breathing
0.713 0.286 0.000
W65-W74 Accidental drowning and submersion
0.713 0.286 0.000
V98-V99 Other and unspecified transport accidents
0.713 0.286 0.000
V95-V97 Air and space transport accidents
0.713 0.286 0.000
V90-V94 Water transport accidents
0.713 0.286 0.000
V70-V79 Bus occupant injured in transport accident
0.713 0.286 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.713 0.286 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.713 0.286 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.713 0.286 0.000
V01-V09 Pedestrian injured in transport accident
0.713 0.286 0.000
S82 Fracture of lower leg, including ankle
0.713 0.287 0.000
I74.5 Embolism and thrombosis of iliac artery
0.712 0.288 0.000
S65 Injury of blood vessels at wrist and hand level
0.712 0.288 0.000
H11.0 Pterygium
0.712 0.288 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.711 0.289 0.000
E11.7 With multiple complications
0.711 0.289 0.000
T87 Complications peculiar to reattachment and amputation
0.711 0.289 0.000
I77.0 Arteriovenous fistula, acquired
0.711 0.289 0.000
J94 Other pleural conditions
0.710 0.289 0.000
I78 Diseases of capillaries
0.710 0.290 0.000
E28.3 Primary ovarian failure
0.710 0.290 0.000
Y46.6 Other and unspecified antiepileptics
0.709 0.291 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.709 0.291 0.000
V20-V29 Motorcycle rider injured in transport accident
0.709 0.291 0.000
I45.3 Trifascicular block
0.709 0.291 0.000
I77.1 Stricture of artery
0.708 0.292 0.000
Y44.2 Anticoagulants
0.708 0.292 0.000
H04.2 Epiphora
0.708 0.292 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.707 0.293 0.000
E83.4 Disorders of magnesium metabolism
0.707 0.293 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.706 0.293 0.000
I52 Other heart disorders in diseases classified elsewhere
0.706 0.294 0.000
I48 Atrial fibrillation and flutter
0.706 0.294 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.706 0.294 0.000
I41 Myocarditis in diseases classified elsewhere
0.706 0.294 0.000
I40 Acute myocarditis
0.706 0.294 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.706 0.294 0.000
I32 Pericarditis in diseases classified elsewhere
0.706 0.294 0.000
W50-W64 Exposure to animate mechanical forces
0.705 0.295 0.000
B15-B19 Viral hepatitis
0.704 0.296 0.000
E34 Other endocrine disorders
0.703 0.297 0.000
I60-I69 Cerebrovascular diseases
0.703 0.297 0.000
V89.2 Person injured in unspecified motor-vehicle accident, traffic
0.702 0.298 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.701 0.299 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.701 0.299 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.700 0.300 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.699 0.301 0.000
Y59 Other and unspecified vaccines and biological substances
0.699 0.301 0.000
Y58 Bacterial vaccines
0.699 0.301 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.699 0.301 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.699 0.301 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.699 0.301 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.699 0.301 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.699 0.301 0.000
X20-X29 Contact with venomous animals and plants
0.698 0.302 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.698 0.302 0.000
S90 Superficial injury of ankle and foot
0.697 0.303 0.000
H53.8 Other visual disturbances
0.697 0.303 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.697 0.303 0.000
J20-J22 Other acute lower respiratory infections
0.697 0.303 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.695 0.305 0.000
G43.3 Complicated migraine
0.695 0.305 0.000
G43.2 Status migrainosus
0.695 0.305 0.000
G43.0 Migraine without aura [common migraine]
0.695 0.305 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.694 0.306 0.000
Y48 Anaesthetics and therapeutic gases
0.694 0.306 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.694 0.306 0.000
F70-F79 Mental retardation
0.694 0.306 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.694 0.306 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.693 0.307 0.000
H54.9 Unspecified visual impairment (binocular)
0.693 0.307 0.000
G62.8 Other specified polyneuropathies
0.693 0.307 0.000
F48 Other neurotic disorders
0.691 0.309 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.690 0.309 0.000
E03 Other hypothyroidism
0.690 0.310 0.000
H11.9 Disorder of conjunctiva, unspecified
0.690 0.310 0.000
I47.0 Reentry ventricular arrhythmia
0.690 0.310 0.000
H04.1 Other disorders of lachrymal gland
0.690 0.310 0.000
I08 Multiple valve diseases
0.690 0.310 0.000
Y53.4 Other laxatives
0.689 0.310 0.000
S59 Other and unspecified injuries of forearm
0.689 0.311 0.000
S58 Traumatic amputation of forearm
0.689 0.311 0.000
S57 Crushing injury of forearm
0.689 0.311 0.000
S55 Injury of blood vessels at forearm level
0.689 0.311 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.689 0.311 0.000
J96 Respiratory failure, not elsewhere classified
0.688 0.311 0.000
J95.0 Tracheostomy malfunction
0.689 0.311 0.000
G50 Disorders of trigeminal nerve
0.688 0.312 0.000
X50-X57 Overexertion, travel and privation
0.686 0.314 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.686 0.314 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.686 0.314 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.686 0.314 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.686 0.314 0.000
T36 Poisoning by systemic antibiotics
0.686 0.314 0.000
F43 Reaction to severe stress, and adjustment disorders
0.685 0.315 0.000
I37 Pulmonary valve disorders
0.685 0.315 0.000
R29.4 Clicking hip
0.685 0.315 0.000
R29.3 Abnormal posture
0.685 0.315 0.000
R29.2 Abnormal reflex
0.685 0.315 0.000
R29.1 Meningismus
0.685 0.315 0.000
R29.0 Tetany
0.685 0.315 0.000
R26.1 Paralytic gait
0.685 0.315 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.685 0.315 0.000
E04.1 Non-toxic single thyroid nodule
0.684 0.316 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.683 0.317 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.683 0.317 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.683 0.317 0.000
S64 Injury of nerves at wrist and hand level
0.683 0.317 0.000
B59 Pneumocystosis
0.683 0.317 0.000
S56.4 Injury of extensor muscle and tendon of other finger(s) at forearm level
0.683 0.317 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.682 0.318 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.681 0.318 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.681 0.318 0.000
A75-A79 Rickettsioses
0.681 0.318 0.000
A70-A74 Other diseases caused by chlamydiae
0.681 0.318 0.000
A65-A69 Other spirochaetal diseases
0.681 0.318 0.000
A20-A28 Certain zoonotic bacterial diseases
0.681 0.318 0.000
A15-A19 Tuberculosis
0.681 0.318 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.681 0.318 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.681 0.318 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.681 0.318 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.681 0.318 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.681 0.318 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.681 0.319 0.000
S61.1 Open wound of finger(s) with damage to nail
0.681 0.319 0.000
T66-T78 Other and unspecified effects of external causes
0.681 0.319 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.681 0.319 0.000
T51 Toxic effect of alcohol
0.681 0.319 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.681 0.319 0.000
J98.3 Compensatory emphysema
0.680 0.320 0.000
J98.2 Interstitial emphysema
0.680 0.320 0.000
R06.6 Hiccough
0.679 0.321 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.679 0.321 0.000
E32 Diseases of thymus
0.679 0.321 0.000
E31 Polyglandular dysfunction
0.679 0.321 0.000
E30 Disorders of puberty, not elsewhere classified
0.679 0.321 0.000
E26 Hyperaldosteronism
0.679 0.321 0.000
E25 Adrenogenital disorders
0.679 0.321 0.000
E20 Hypoparathyroidism
0.679 0.321 0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension
0.679 0.321 0.000
I72.2 Aneurysm of renal artery
0.679 0.321 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.678 0.322 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.678 0.322 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.678 0.322 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.677 0.323 0.000
X10 Contact with hot drinks, food, fats and cooking oils
0.676 0.323 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.676 0.324 0.000
R71 Abnormality of red blood cells
0.675 0.325 0.000
I42 Cardiomyopathy
0.675 0.325 0.000
E23.0 Hypopituitarism
0.675 0.325 0.000
E06 Thyroiditis
0.674 0.326 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.674 0.326 0.000
S82.3 Fracture of lower end of tibia
0.673 0.327 0.000
I25.3 Aneurysm of heart
0.673 0.327 0.000
T23.2 Burn of second degree of wrist and hand
0.673 0.327 0.000
E10.4 With neurological complications
0.672 0.327 0.000
Q60-Q64 Congenital malformations of the urinary system
0.672 0.328 0.000
T88.5 Other complications of anaesthesia
0.672 0.328 0.000
G54 Nerve root and plexus disorders
0.672 0.328 0.000
T23.3 Burn of third degree of wrist and hand
0.672 0.328 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.671 0.329 0.000
S99 Other and unspecified injuries of ankle and foot
0.671 0.329 0.000
I45.9 Conduction disorder, unspecified
0.671 0.329 0.000
Y45.1 Salicylates
0.670 0.330 0.000
R22.0 Localised swelling, mass and lump, head
0.668 0.332 0.000
L50-L54 Urticaria and erythema
0.666 0.334 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.666 0.334 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.666 0.334 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.666 0.334 0.000
F38 Other mood [affective] disorders
0.666 0.334 0.000
F34 Persistent mood [affective] disorders
0.666 0.334 0.000
F39 Unspecified mood [affective] disorder
0.666 0.334 0.000
E11.4 With neurological complications
0.665 0.335 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.665 0.335 0.000
I72.4 Aneurysm of artery of lower extremity
0.664 0.336 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.663 0.337 0.000
S66.8 Injury of other muscles and tendons at wrist and hand level
0.662 0.338 0.000
S71 Open wound of hip and thigh
0.662 0.338 0.000
I74.8 Embolism and thrombosis of other arteries
0.662 0.338 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.662 0.338 0.000
S68 Traumatic amputation of wrist and hand
0.662 0.338 0.000
I45.8 Other specified conduction disorders
0.661 0.339 0.000
E85 Amyloidosis
0.661 0.339 0.000
S70.9 Superficial injury of hip and thigh, unspecified
0.661 0.339 0.000
E13 Other specified diabetes mellitus
0.660 0.340 0.000
V10-V19 Pedal cyclist injured in transport accident
0.660 0.340 0.000
R27 Other lack of coordination
0.660 0.340 0.000
I20.9 Angina pectoris, unspecified
0.660 0.340 0.000
R25.0 Abnormal head movements
0.659 0.341 0.000
J00-J06 Acute upper respiratory infections
0.659 0.341 0.000
J69.0 Pneumonitis due to food and vomit
0.658 0.342 0.000
L20-L30 Dermatitis and eczema
0.658 0.342 0.000
B65-B83 Helminthiases
0.657 0.343 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.657 0.343 0.000
S91 Open wound of ankle and foot
0.656 0.343 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.656 0.343 0.000
I77.5 Necrosis of artery
0.656 0.343 0.000
I77.4 Coeliac artery compression syndrome
0.656 0.343 0.000
I77.3 Arterial fibromuscular dysplasia
0.656 0.343 0.000
I77.2 Rupture of artery
0.656 0.343 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.656 0.344 0.000
G81 Hemiplegia
0.655 0.345 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.654 0.346 0.000
I20.0 Unstable angina
0.653 0.347 0.000
Y57.8 Other drugs and medicaments
0.652 0.347 0.000
I72.8 Aneurysm of other specified arteries
0.652 0.348 0.000
I69 Sequelae of cerebrovascular disease
0.652 0.348 0.000
I45.4 Nonspecific intraventricular block
0.651 0.349 0.000
I45.0 Right fascicular block
0.651 0.349 0.000
E27 Other disorders of adrenal gland
0.650 0.350 0.000
S98 Traumatic amputation of ankle and foot
0.650 0.350 0.000
S97 Crushing injury of ankle and foot
0.650 0.350 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.650 0.350 0.000
S95 Injury of blood vessels at ankle and foot level
0.650 0.350 0.000
S94 Injury of nerves at ankle and foot level
0.650 0.350 0.000
G70-G73 Diseases of myoneural junction and muscle
0.650 0.350 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.649 0.351 0.000
S51.7 Multiple open wounds of forearm
0.648 0.352 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.648 0.352 0.000
T25 Burn and corrosion of ankle and foot
0.648 0.352 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.648 0.352 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.648 0.352 0.000
T21 Burn and corrosion of trunk
0.648 0.352 0.000
T20 Burn and corrosion of head and neck
0.648 0.352 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.647 0.353 0.000
B33 Other viral diseases, not elsewhere classified
0.647 0.353 0.000
B30 Viral conjunctivitis
0.647 0.353 0.000
B27 Infectious mononucleosis
0.647 0.353 0.000
B26 Mumps
0.647 0.353 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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