TreeWAS – Variant ID: rs11175944

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E11.9 Without complications	0.065	0.935	0.000
E11 Non-insulin-dependent diabetes mellitus	0.043	0.957	0.000
E10.9 Without complications	0.042	0.958	0.000
E10 Insulin-dependent diabetes mellitus	0.042	0.958	0.000
E10-E14 Diabetes mellitus	0.042	0.958	0.000
E14 Unspecified diabetes mellitus	0.037	0.963	0.000
E10.1 With ketoacidosis	0.036	0.964	0.000
E11.8 With unspecified complications	0.034	0.966	0.000
E11.0 With coma	0.033	0.967	0.000
E14.5 With peripheral circulatory complications	0.032	0.968	0.000
E14.9 Without complications	0.032	0.968	0.000
E11.1 With ketoacidosis	0.032	0.968	0.000
E10.8 With unspecified complications	0.032	0.968	0.000
E10.2 With renal complications	0.032	0.968	0.000
E11.7 With multiple complications	0.031	0.969	0.000
E10.7 With multiple complications	0.030	0.970	0.000
E10.6 With other specified complications	0.030	0.970	0.000
E10.0 With coma	0.030	0.970	0.000
E12 Malnutrition-related diabetes mellitus	0.030	0.970	0.000
E10.4 With neurological complications	0.030	0.970	0.000
E11.4 With neurological complications	0.029	0.971	0.000
E13 Other specified diabetes mellitus	0.028	0.972	0.000
E14.8 With unspecified complications	0.027	0.973	0.000
E14.7 With multiple complications	0.027	0.973	0.000
E14.6 With other specified complications	0.027	0.973	0.000
E14.4 With neurological complications	0.027	0.973	0.000
E14.2 Withrenal complications	0.027	0.973	0.000
E14.1 With ketoacidosis	0.027	0.973	0.000
E14.0 With coma	0.027	0.973	0.000
E11.6 With other specified complications	0.027	0.973	0.000
E10.3 With ophthalmic complications	0.026	0.974	0.000
E11.2 With renal complications	0.025	0.974	0.000
E10.5 With peripheral circulatory complications	0.025	0.975	0.000
E14.3 With ophthalmic complications	0.024	0.976	0.000
E12.9 Without complications	0.022	0.978	0.000
E12.8 With unspecified complications	0.022	0.978	0.000
E12.7 With multiple complications	0.022	0.978	0.000
E12.6 With other specified complications	0.022	0.978	0.000
E12.5 With peripheral circulatory complications	0.022	0.978	0.000
E12.4 With neurological complications	0.022	0.978	0.000
E12.3 With ophthalmic complications	0.022	0.978	0.000
E12.2 With renal complications	0.022	0.978	0.000
E12.1 With ketoacidosis	0.022	0.978	0.000
E12.0 With coma	0.022	0.978	0.000
E13.8 With unspecified complications	0.020	0.980	0.000
E13.7 With multiple complications	0.020	0.980	0.000
E13.6 With other specified complications	0.020	0.980	0.000
E13.5 With peripheral circulatory complications	0.020	0.980	0.000
E13.4 With neurological complications	0.020	0.980	0.000
E13.3 With ophthalmic complications	0.020	0.980	0.000
E13.2 With renal complications	0.020	0.980	0.000
E13.1 With ketoacidosis	0.020	0.980	0.000
E13.0 With coma	0.020	0.980	0.000
E11.3 With ophthalmic complications	0.020	0.980	0.000
E11.5 With peripheral circulatory complications	0.019	0.981	0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene	0.000	0.982	0.018
E13.9 Without complications	0.018	0.982	0.000
Z98.0 Intestinal bypass and anastomosis status	0.013	0.987	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.012	0.988	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.011	0.989	0.000
Y45.0 Opioids and related analgesics	0.011	0.989	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.010	0.990	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.010	0.990	0.000
Y45.1 Salicylates	0.009	0.991	0.000
Y45.2 Propionic acid derivatives	0.009	0.991	0.000
Y57 Other and unspecified drugs and medicaments	0.009	0.991	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.009	0.991	0.000
Y42.5 Other oestrogens and progestogens	0.009	0.991	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.009	0.991	0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.008	0.991	0.000
Y45.5 4-Aminophenol derivatives	0.008	0.991	0.000
Y45.4 Antirheumatics	0.008	0.991	0.000
Y45.8 Other analgesics and antipyretics	0.008	0.991	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.008	0.992	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.008	0.992	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.008	0.992	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.008	0.992	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.008	0.992	0.000
Y43 Primarily systemic agents	0.008	0.992	0.000
Y57.5 X-ray contrast media	0.007	0.992	0.000
Y59 Other and unspecified vaccines and biological substances	0.007	0.993	0.000
Y58 Bacterial vaccines	0.007	0.993	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.007	0.993	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.007	0.993	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.007	0.993	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.007	0.993	0.000
Y42.9 Other and unspecified hormone antagonists	0.007	0.993	0.000
Y42.4 Oral contraceptives	0.007	0.993	0.000
Y42.2 Antithyroid drugs	0.007	0.993	0.000
Y42.1 Thyroid hormones and substitutes	0.007	0.993	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.007	0.993	0.000
Y57.8 Other drugs and medicaments	0.007	0.993	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.007	0.993	0.000
Y42.7 Androgens and anabolic congeners	0.007	0.993	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.007	0.993	0.000
Y48 Anaesthetics and therapeutic gases	0.007	0.993	0.000
Y57.9 Drug or medicament, unspecified	0.007	0.993	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.007	0.993	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.007	0.993	0.000
Y43.0 Antiallergic and antiemetic drugs	0.007	0.993	0.000
Y57.7 Vitamins, not elsewhere classified	0.007	0.993	0.000
Y57.6 Other diagnostic agents	0.007	0.993	0.000
Y57.4 Pharmaceutical excipients	0.007	0.993	0.000
Y57.3 Alcohol deterrents	0.007	0.993	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.007	0.993	0.000
Y57.1 Lipotropic drugs	0.007	0.993	0.000
Y57.0 Appetite depressants [anorectics]	0.007	0.993	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.007	0.993	0.000
Y44 Agents primarily affecting blood constituents	0.006	0.993	0.000
M65.34 Trigger finger-Hand	0.006	0.994	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.006	0.994	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.006	0.994	0.000
Y53.7 Emetics	0.006	0.994	0.000
Y53.6 Antidiarrhoeal drugs	0.006	0.994	0.000
Y53.5 Digestants	0.006	0.994	0.000
Y53.4 Other laxatives	0.006	0.994	0.000
Y53.3 Saline and osmotic laxatives	0.006	0.994	0.000
Y53.2 Stimulant laxatives	0.006	0.994	0.000
Y53.0 Histamine H2-receptor antagonists	0.006	0.994	0.000
I77 Other disorders of arteries and arterioles	0.006	0.994	0.000
E23.0 Hypopituitarism	0.006	0.994	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.006	0.994	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.006	0.994	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.006	0.994	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.006	0.994	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.006	0.994	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.006	0.994	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.006	0.994	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.006	0.994	0.000
Y51.0 Anticholinesterase agents	0.006	0.994	0.000
Y49.5 Other antipsychotics and neuroleptics	0.006	0.994	0.000
Y49.2 Other and unspecified antidepressants	0.006	0.994	0.000
Y54.8 Agents affecting uric acid metabolism	0.006	0.994	0.000
Y43.3 Other antineoplastic drugs	0.006	0.994	0.000
Y49.9 Psychotropic drug, unspecified	0.006	0.994	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.006	0.994	0.000
Y49.7 Psychostimulants with abuse potential	0.006	0.994	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.006	0.994	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.006	0.994	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.006	0.994	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.006	0.994	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.006	0.994	0.000
Y54.4 Loop [high-ceiling] diuretics	0.006	0.994	0.000
K40 Inguinal hernia	0.000	0.994	0.006
Y52 Agents primarily affecting the cardiovascular system	0.006	0.994	0.000
Y43.9 Primarily systemic agent, unspecified	0.006	0.994	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.006	0.994	0.000
Y43.6 Enzymes, not elsewhere classified	0.006	0.994	0.000
Y43.5 Acidifying and alkalising agents	0.006	0.994	0.000
Y43.2 Antineoplastic natural products	0.006	0.994	0.000
E23 Hypofunction and other disorders of pituitary gland	0.006	0.994	0.000
Y46.8 Antispasticity drugs	0.005	0.994	0.000
Y46.7 Anti-Parkinsonism drugs	0.005	0.994	0.000
Y46.6 Other and unspecified antiepileptics	0.005	0.994	0.000
Y46.5 Valproic acid	0.005	0.994	0.000
Y46.4 Iminostilbenes	0.005	0.994	0.000
Y46.3 Deoxybarbiturates	0.005	0.994	0.000
Y46.2 Hydantoin derivatives	0.005	0.994	0.000
Y46.1 Oxazolidinediones	0.005	0.994	0.000
Y46.0 Succinimides	0.005	0.994	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.005	0.994	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.005	0.994	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.005	0.994	0.000
Y47.4 Bromine compounds	0.005	0.994	0.000
Y47.3 Paraldehyde	0.005	0.994	0.000
Y47.2 Chloral derivatives	0.005	0.994	0.000
Y47.1 Benzodiazepines	0.005	0.994	0.000
Y47.0 Barbiturates, not elsewhere classified	0.005	0.994	0.000
Y50.9 Central nervous system stimulant, unspecified	0.005	0.994	0.000
Y50.8 Other central nervous system stimulants	0.005	0.994	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.005	0.994	0.000
Y50.1 Opioid receptor antagonists	0.005	0.994	0.000
Y50.0 Analeptics	0.005	0.994	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.005	0.994	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.005	0.994	0.000
Y55.5 Anticommon cold drugs	0.005	0.994	0.000
Y55.4 Expectorants	0.005	0.994	0.000
Y55.3 Antitussives	0.005	0.994	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.005	0.994	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.005	0.994	0.000
Y55.0 Oxytocic drugs	0.005	0.994	0.000
Y58.9 Other and unspecified bacterial vaccines	0.005	0.994	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.005	0.994	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.005	0.994	0.000
Y58.5 Diphtheria vaccine	0.005	0.994	0.000
Y58.4 Tetanus vaccine	0.005	0.994	0.000
Y58.3 Plague vaccine	0.005	0.994	0.000
Y58.2 Cholera vaccine	0.005	0.994	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.005	0.994	0.000
Y58.0 BCG vaccine	0.005	0.994	0.000
Y59.9 Vaccine or biological substance, unspecified	0.005	0.994	0.000
Y59.8 Other specified vaccines and biological substances	0.005	0.994	0.000
Y59.3 Immunoglobulin	0.005	0.994	0.000
Y59.2 Protozoal vaccines	0.005	0.994	0.000
Y59.1 Rickettsial vaccines	0.005	0.994	0.000
Y59.0 Viral vaccines	0.005	0.994	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.006	0.994	0.000
Y54.9 Mineral salts, not elsewhere classified	0.005	0.994	0.000
Y54.7 Agents affecting calcification	0.005	0.994	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.005	0.994	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.005	0.994	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.005	0.994	0.000
Y54.0 Mineralocorticoids	0.005	0.994	0.000
Y54.5 Other diuretics	0.005	0.994	0.000
Y56.9 Topical agent, unspecified	0.005	0.994	0.000
Y56.8 Other topical agents	0.005	0.994	0.000
Y56.7 Dental drugs, topically applied	0.005	0.994	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.005	0.994	0.000
Y56.5 Ophthalmological drugs and preparations	0.005	0.994	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.005	0.994	0.000
Y56.3 Emollients, demulcents and protectants	0.005	0.994	0.000
Y56.2 Local astringents and local detergents	0.005	0.994	0.000
Y56.1 Antipruritics	0.005	0.994	0.000
I77.6 Arteritis, unspecified	0.005	0.994	0.000
Y48.5 Therapeutic gases	0.005	0.994	0.000
Y48.4 Anaesthetic, unspecified	0.005	0.994	0.000
Y48.2 Other and unspecified general anaesthetics	0.005	0.994	0.000
Y48.1 Parenteral anaesthetics	0.005	0.994	0.000
Y48.0 Inhaled anaesthetics	0.005	0.994	0.000
Y43.1 Antineoplastic antimetabolites	0.005	0.995	0.000
I78 Diseases of capillaries	0.005	0.995	0.000
I74 Arterial embolism and thrombosis	0.005	0.995	0.000
I77.8 Other specified disorders of arteries and arterioles	0.005	0.995	0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.005	0.995	0.000
Y41.5 Antiviral drugs	0.005	0.995	0.000
Y41.4 Anthelminthics	0.005	0.995	0.000
Y41.3 Other antiprotozoal drugs	0.005	0.995	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.005	0.995	0.000
Y41.1 Antimycobacterial drugs	0.005	0.995	0.000
Y41.0 Sulphonamides	0.005	0.995	0.000
E20-E35 Disorders of other endocrine glands	0.005	0.995	0.000
M35.0 Sicca syndrome [Sjogren]	0.005	0.995	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.005	0.995	0.000
Z98 Other postsurgical states	0.005	0.995	0.000
Y48.3 Local anaesthetics	0.005	0.995	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.005	0.995	0.000
N50.8 Other specified disorders of male genital organs	0.000	0.995	0.005
Y40 Systemic antibiotics	0.005	0.995	0.000
I77.0 Arteriovenous fistula, acquired	0.005	0.995	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.005	0.995	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.005	0.995	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.005	0.995	0.000
Y44.7 Plasma substitutes	0.005	0.995	0.000
Y44.6 Natural blood and blood products	0.005	0.995	0.000
Y44.5 Thrombolytic drugs	0.005	0.995	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.005	0.995	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.005	0.995	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.005	0.995	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.005	0.995	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.005	0.995	0.000
I77.5 Necrosis of artery	0.005	0.995	0.000
I77.4 Coeliac artery compression syndrome	0.005	0.995	0.000
I77.3 Arterial fibromuscular dysplasia	0.005	0.995	0.000
I77.2 Rupture of artery	0.005	0.995	0.000
I78.8 Other diseases of capillaries	0.005	0.995	0.000
Z98.2 Presence of cerebrospinal fluid drainage device	0.005	0.995	0.000
I74.8 Embolism and thrombosis of other arteries	0.005	0.995	0.000
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene	0.000	0.995	0.005
N92.3 Ovulation bleeding	0.005	0.995	0.000
E23.7 Disorder of pituitary gland, unspecified	0.005	0.995	0.000
I78.1 Naevus, nonneoplastic	0.005	0.995	0.000
M65.3 Trigger finger	0.005	0.995	0.000
I72.4 Aneurysm of artery of lower extremity	0.005	0.995	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.005	0.995	0.000
Z45.2 Adjustment and management of vascular access device	0.005	0.995	0.000
E27 Other disorders of adrenal gland	0.005	0.995	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.005	0.995	0.000
I72 Other aneurysm	0.004	0.995	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.004	0.995	0.000
K40.4 Unilateral or unspecified inguinal hernia, with gangrene	0.000	0.995	0.004
K40.1 Bilateral inguinal hernia, with gangrene	0.000	0.995	0.004
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene	0.000	0.995	0.004
E34 Other endocrine disorders	0.004	0.995	0.000
I77.1 Stricture of artery	0.004	0.996	0.000
Z98.8 Other specified postsurgical states	0.004	0.996	0.000
Y52.1 Calcium-channel blockers	0.004	0.996	0.000
N30.9 Cystitis, unspecified	0.004	0.996	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.004	0.996	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.004	0.996	0.000
Y52.7 Peripheral vasodilators	0.004	0.996	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.004	0.996	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.004	0.996	0.000
E23.6 Other disorders of pituitary gland	0.004	0.996	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.004	0.996	0.000
E23.1 Drug-induced hypopituitarism	0.004	0.996	0.000
Y54.3 Benzothiadiazine derivatives	0.004	0.996	0.000
E26 Hyperaldosteronism	0.004	0.996	0.000
E53.8 Deficiency of other specified B group vitamins	0.000	0.996	0.004
Y43.4 Immunosuppressive agents	0.004	0.996	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.004	0.996	0.000
E29 Testicular dysfunction	0.004	0.996	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.004	0.996	0.000
Y40.3 Macrolides	0.004	0.996	0.000
E27.8 Other specified disorders of adrenal gland	0.004	0.996	0.000
E16 Other disorders of pancreatic internal secretion	0.004	0.996	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.004	0.996	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.004	0.996	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.004	0.996	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.004	0.996	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.004	0.996	0.000
I78.9 Disease of capillaries, unspecified	0.004	0.996	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.004	0.996	0.000
E32 Diseases of thymus	0.004	0.996	0.000
E31 Polyglandular dysfunction	0.004	0.996	0.000
E30 Disorders of puberty, not elsewhere classified	0.004	0.996	0.000
E25 Adrenogenital disorders	0.004	0.996	0.000
E20 Hypoparathyroidism	0.004	0.996	0.000
E24 Cushing's syndrome	0.004	0.996	0.000
C34 Malignant neoplasm of bronchus and lung	0.004	0.996	0.000
C34.9 Bronchus or lung, unspecified	0.004	0.996	0.000
Y40.7 Antifungal antibiotics, systemically used	0.004	0.996	0.000
Y40.6 Rifamycins	0.004	0.996	0.000
Y40.5 Aminoglycosides	0.004	0.996	0.000
Y40.4 Tetracyclines	0.004	0.996	0.000
Y40.2 Chloramphenicol group	0.004	0.996	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.004	0.996	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.004	0.996	0.000
Y44.2 Anticoagulants	0.004	0.996	0.000
L98.9 Disorder of skin and subcutaneous tissue, unspecified	0.004	0.996	0.000
E23.2 Diabetes insipidus	0.004	0.996	0.000
C34.3 Lower lobe, bronchus or lung	0.004	0.996	0.000
E34.0 Carcinoid syndrome	0.004	0.996	0.000
Y40.0 Penicillins	0.004	0.996	0.000
I74.5 Embolism and thrombosis of iliac artery	0.004	0.996	0.000
E16.2 Hypoglycaemia, unspecified	0.004	0.996	0.000
E34.8 Other specified endocrine disorders	0.004	0.996	0.000
E22 Hyperfunction of pituitary gland	0.004	0.996	0.000
C34.1 Upper lobe, bronchus or lung	0.004	0.996	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.004	0.996	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.004	0.996	0.000
C34.2 Middle lobe, bronchus or lung	0.004	0.996	0.000
D25.0 Submucous leiomyoma of uterus	0.004	0.996	0.000
E26.0 Primary hyperaldosteronism	0.004	0.996	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.003	0.996	0.000
M65.39 Trigger finger-Site unspec	0.003	0.996	0.000
M65.38 Trigger finger-Other	0.003	0.996	0.000
M65.37 Trigger finger-Ankle/foot	0.003	0.996	0.000
M65.36 Trigger finger-Lower leg	0.003	0.996	0.000
M65.35 Trigger finger-Pelvic/thigh	0.003	0.996	0.000
M65.33 Trigger finger-Forearm	0.003	0.996	0.000
M65.32 Trigger finger-Upper arm	0.003	0.996	0.000
M65.31 Trigger finger-Shldr region	0.003	0.996	0.000
M65.30 Trigger finger-Mult sites	0.003	0.996	0.000
E27.5 Adrenomedullary hyperfunction	0.003	0.996	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.003	0.996	0.000
E27.2 Addisonian crisis	0.003	0.996	0.000
E27.0 Other adrenocortical overactivity	0.003	0.996	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.003	0.996	0.000
E21.4 Other specified disorders of parathyroid gland	0.003	0.996	0.000
E21.2 Other hyperparathyroidism	0.003	0.996	0.000
I72.9 Aneurysm of unspecified site	0.003	0.996	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.003	0.996	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.003	0.996	0.000
I72.2 Aneurysm of renal artery	0.003	0.996	0.000
I72.1 Aneurysm of artery of upper extremity	0.003	0.996	0.000
I72.0 Aneurysm of carotid artery	0.003	0.996	0.000
E15 Nondiabetic hypoglycaemic coma	0.003	0.996	0.000
C34.0 Main bronchus	0.003	0.996	0.000
I72.8 Aneurysm of other specified arteries	0.003	0.996	0.000
E34.5 Androgen resistance syndrome	0.003	0.996	0.000
E34.4 Constitutional tall stature	0.003	0.996	0.000
E34.3 Short stature, not elsewhere classified	0.003	0.996	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.003	0.996	0.000
E34.1 Other hypersecretion of intestinal hormones	0.003	0.996	0.000
N50 Other disorders of male genital organs	0.000	0.997	0.003
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.003	0.997	0.000
E26.9 Hyperaldosteronism, unspecified	0.003	0.997	0.000
E26.8 Other hyperaldosteronism	0.003	0.997	0.000
E26.1 Secondary hyperaldosteronism	0.003	0.997	0.000
E29.1 Testicular hypofunction	0.003	0.997	0.000
E53 Deficiency of other B group vitamins	0.001	0.997	0.002
E27.9 Disorder of adrenal gland, unspecified	0.003	0.997	0.000
N50.1 Vascular disorders of male genital organs	0.000	0.997	0.003
E50-E64 Other nutritional deficiencies	0.003	0.997	0.001
E29.9 Testicular dysfunction, unspecified	0.003	0.997	0.000
E29.8 Other testicular dysfunction	0.003	0.997	0.000
E29.0 Testicular hyperfunction	0.003	0.997	0.000
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)	0.003	0.997	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.003	0.997	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.003	0.997	0.000
E16.4 Abnormal secretion of gastrin	0.003	0.997	0.000
E16.3 Increased secretion of glucagon	0.003	0.997	0.000
E16.1 Other hypoglycaemia	0.003	0.997	0.000
E28 Ovarian dysfunction	0.003	0.997	0.000
I73 Other peripheral vascular diseases	0.003	0.997	0.000
E20.8 Other hypoparathyroidism	0.003	0.997	0.000
E20.1 Pseudohypoparathyroidism	0.003	0.997	0.000
E20.0 Idiopathic hypoparathyroidism	0.003	0.997	0.000
E25.9 Adrenogenital disorder, unspecified	0.003	0.997	0.000
E25.8 Other adrenogenital disorders	0.003	0.997	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.003	0.997	0.000
E30.9 Disorder of puberty, unspecified	0.003	0.997	0.000
E30.8 Other disorders of puberty	0.003	0.997	0.000
E30.1 Precocious puberty	0.003	0.997	0.000
E30.0 Delayed puberty	0.003	0.997	0.000
E31.9 Polyglandular dysfunction, unspecified	0.003	0.997	0.000
E31.8 Other polyglandular dysfunction	0.003	0.997	0.000
E31.1 Polyglandular hyperfunction	0.003	0.997	0.000
E31.0 Autoimmune polyglandular failure	0.003	0.997	0.000
E32.9 Disease of thymus, unspecified	0.003	0.997	0.000
E32.8 Other diseases of thymus	0.003	0.997	0.000
E32.1 Abscess of thymus	0.003	0.997	0.000
E32.0 Persistent hyperplasia of thymus	0.003	0.997	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.003	0.997	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.003	0.997	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.003	0.997	0.000
E40-E46 Malnutrition	0.003	0.997	0.000
E20.9 Hypoparathyroidism, unspecified	0.003	0.997	0.000
Y40.8 Other systemic antibiotics	0.003	0.997	0.000
C34.8 Overlapping lesion of bronchus and lung	0.003	0.997	0.000
E21.3 Hyperparathyroidism, unspecified	0.003	0.997	0.000
E21.0 Primary hyperparathyroidism	0.003	0.997	0.000
E24.8 Other Cushing's syndrome	0.003	0.997	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.003	0.997	0.000
E24.3 Ectopic ACTH syndrome	0.003	0.997	0.000
E24.2 Drug-induced Cushing's syndrome	0.003	0.997	0.000
E24.1 Nelson's syndrome	0.003	0.997	0.000
E24.0 Pituitary-dependent Cushing's disease	0.003	0.997	0.000
M65 Synovitis and tenosynovitis	0.003	0.997	0.000
C78.0 Secondary malignant neoplasm of lung	0.003	0.997	0.000
E24.9 Cushing's syndrome, unspecified	0.003	0.997	0.000
I70 Atherosclerosis	0.003	0.997	0.000
M65.4 Radial styloid tenosynovitis [de Quervain]	0.003	0.997	0.000
M35 Other systemic involvement of connective tissue	0.003	0.997	0.000
H83.0 Labyrinthitis	0.003	0.997	0.000
E27.1 Primary adrenocortical insufficiency	0.003	0.997	0.000
Y40.9 Systemic antibiotic, unspecified	0.003	0.997	0.000
E22.1 Hyperprolactinaemia	0.003	0.997	0.000
I73.0 Raynaud's syndrome	0.003	0.997	0.000
E34.9 Endocrine disorder, unspecified	0.003	0.997	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.003	0.997	0.000
E22.8 Other hyperfunction of pituitary gland	0.003	0.997	0.000
I72.3 Aneurysm of iliac artery	0.003	0.997	0.000
E22.0 Acromegaly and pituitary gigantism	0.003	0.997	0.000
M35.2 Behcet's disease	0.003	0.997	0.000
N50.9 Disorder of male genital organs, unspecified	0.000	0.997	0.003
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.002	0.997	0.000
I79.1 Aortitis in diseases classified elsewhere	0.002	0.997	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.002	0.997	0.000
E53.9 Vitamin B deficiency, unspecified	0.001	0.997	0.002
E53.1 Pyridoxine deficiency	0.001	0.997	0.002
E53.0 Riboflavin deficiency	0.001	0.997	0.002
K40.2 Bilateral inguinal hernia, without obstruction or gangrene	0.000	0.997	0.003
N50.0 Atrophy of testis	0.000	0.997	0.003
M24.02 Loose body in joint (Upper arm)	0.003	0.997	0.000
M35.3 Polymyalgia rheumatica	0.003	0.997	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.002	0.997	0.001
E63 Other nutritional deficiencies	0.002	0.997	0.001
E56 Other vitamin deficiencies	0.002	0.997	0.001
E51 Thiamine deficiency	0.002	0.997	0.001
E50 Vitamin A deficiency	0.002	0.997	0.001
E60 Dietary zinc deficiency	0.002	0.997	0.001
E59 Dietary selenium deficiency	0.002	0.997	0.001
E58 Dietary calcium deficiency	0.002	0.997	0.001
E54 Ascorbic acid deficiency	0.002	0.997	0.001
E52 Niacin deficiency [pellagra]	0.002	0.997	0.001
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.003	0.997	0.000
E28.9 Ovarian dysfunction, unspecified	0.002	0.997	0.000
E28.8 Other ovarian dysfunction	0.002	0.997	0.000
E28.1 Androgen excess	0.002	0.997	0.000
E28.0 Oestrogen excess	0.002	0.997	0.000
I73.8 Other specified peripheral vascular diseases	0.003	0.997	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.003	0.997	0.000
E28.3 Primary ovarian failure	0.002	0.997	0.000
N92.1 Excessive and frequent menstruation with irregular cycle	0.003	0.997	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.002	0.997	0.000
E45 Retarded development following protein-energy malnutrition	0.002	0.997	0.000
E43 Unspecified severe protein-energy malnutrition	0.002	0.997	0.000
E42 Marasmic kwashiorkor	0.002	0.997	0.000
E41 Nutritional marasmus	0.002	0.997	0.000
E40 Kwashiorkor	0.002	0.997	0.000
M65.8 Other synovitis and tenosynovitis	0.002	0.997	0.000
M65.2 Calcific tendinitis	0.002	0.997	0.000
M65.0 Abscess of tendon sheath	0.002	0.997	0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess	0.000	0.997	0.003
E61 Deficiency of other nutrient elements	0.002	0.997	0.001
E65-E68 Obesity and other hyperalimentation	0.003	0.997	0.000
M35.1 Other overlap syndromes	0.002	0.997	0.000
I70.9 Generalised and unspecified atherosclerosis	0.002	0.997	0.000
I70.8 Atherosclerosis of other arteries	0.002	0.997	0.000
I70.1 Atherosclerosis of renal artery	0.002	0.997	0.000
M65.1 Other infective (teno)synovitis	0.002	0.997	0.000
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec	0.002	0.997	0.000
M65.48 Radial styloid tenosynovitis [de Quervain]-Other	0.002	0.997	0.000
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot	0.002	0.997	0.000
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg	0.002	0.997	0.000
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh	0.002	0.997	0.000
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm	0.002	0.997	0.000
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region	0.002	0.997	0.000
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)	0.002	0.997	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.002	0.997	0.000
M35.8 Other specified systemic involvement of connective tissue	0.002	0.997	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.002	0.997	0.000
M35.5 Multifocal fibrosclerosis	0.002	0.997	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.002	0.997	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.002	0.997	0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.002	0.997	0.000
N99.3 Prolapse of vaginal vault after hysterectomy	0.000	0.998	0.002
E55 Vitamin D deficiency	0.002	0.998	0.001
M65.9 Synovitis and tenosynovitis, unspecified	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations