TreeWAS – Variant ID: rs11199914

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
N40 Hyperplasia of prostate	0.520	0.480	0.000
N41 Inflammatory diseases of prostate	0.332	0.668	0.000
N40-N51 Diseases of male genital organs	0.328	0.672	0.000
N41.0 Acute prostatitis	0.313	0.687	0.000
N41.1 Chronic prostatitis	0.309	0.691	0.000
N41.9 Inflammatory disease of prostate, unspecified	0.306	0.694	0.000
N50 Other disorders of male genital organs	0.269	0.731	0.000
N50.1 Vascular disorders of male genital organs	0.261	0.739	0.000
N45 Orchitis and epididymitis	0.259	0.741	0.000
N44 Torsion of testis	0.247	0.753	0.000
N42 Other disorders of prostate	0.243	0.757	0.000
N51 Disorders of male genital organs in diseases classified elsewhere	0.238	0.762	0.000
N41.3 Prostatocystitis	0.238	0.762	0.000
N41.2 Abscess of prostate	0.238	0.762	0.000
N41.8 Other inflammatory diseases of prostate	0.229	0.771	0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess	0.228	0.772	0.000
N42.2 Atrophy of prostate	0.197	0.803	0.000
N42.1 Congestion and haemorrhage of prostate	0.196	0.804	0.000
N42.0 Calculus of prostate	0.190	0.810	0.000
N42.3 Dysplasia of prostate	0.189	0.811	0.000
N46 Male infertility	0.178	0.821	0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified	0.178	0.822	0.000
N50.0 Atrophy of testis	0.175	0.825	0.000
N51.2 Balanitis in diseases classified elsewhere	0.173	0.826	0.000
N51.8 Other disorders of male genital organs in diseases classified elsewhere	0.171	0.829	0.000
N51.1 Disorders of testis and epididymis in diseases classified elsewhere	0.171	0.829	0.000
N51.0 Disorders of prostate in diseases classified elsewhere	0.171	0.829	0.000
N50.9 Disorder of male genital organs, unspecified	0.166	0.834	0.000
C50.9 Breast, unspecified	0.000	0.841	0.159
N42.9 Disorder of prostate, unspecified	0.156	0.844	0.000
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess	0.141	0.858	0.000
C50.2 Upper-inner quadrant of breast	0.000	0.865	0.135
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens	0.134	0.866	0.000
C50 Malignant neoplasm of breast	0.000	0.867	0.133
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.129	0.871	0.000
N49.9 Inflammatory disorder of unspecified male genital organ	0.128	0.872	0.000
N49.0 Inflammatory disorders of seminal vesicle	0.128	0.872	0.000
N43 Hydrocele and spermatocele	0.125	0.875	0.000
C50.3 Lower-inner quadrant of breast	0.000	0.883	0.117
N49.8 Inflammatory disorders of other specified male genital organs	0.109	0.891	0.000
C50.6 Axillary tail of breast	0.000	0.905	0.094
C50.1 Central portion of breast	0.000	0.907	0.093
N43.4 Spermatocele	0.092	0.908	0.000
N43.1 Infected hydrocele	0.090	0.910	0.000
N43.0 Encysted hydrocele	0.090	0.910	0.000
N49.2 Inflammatory disorders of scrotum	0.088	0.912	0.000
N48 Other disorders of penis	0.087	0.913	0.000
N48.2 Other inflammatory disorders of penis	0.081	0.919	0.000
N43.2 Other hydrocele	0.079	0.921	0.000
N42.8 Other specified disorders of prostate	0.079	0.921	0.000
N48.0 Leukoplakia of penis	0.077	0.923	0.000
C50.5 Lower-outer quadrant of breast	0.000	0.924	0.076
C50.0 Nipple and areola	0.000	0.929	0.071
N48.3 Priapism	0.063	0.937	0.000
N50.8 Other specified disorders of male genital organs	0.061	0.939	0.000
N48.9 Disorder of penis, unspecified	0.060	0.940	0.000
C50.4 Upper-outer quadrant of breast	0.000	0.941	0.059
N48.5 Ulcer of penis	0.055	0.944	0.000
C50-C50 Malignant neoplasm of breast	0.000	0.944	0.055
M25.78 Osteophyte (Other)	0.054	0.946	0.000
N48.8 Other specified disorders of penis	0.053	0.947	0.000
D63.0 Anaemia in neoplastic disease	0.000	0.955	0.045
M19.90 Arthrosis, unspecified (Multiple sites)	0.000	0.956	0.044
M25.7 Osteophyte	0.044	0.956	0.000
M25.71 Osteophyte (Shoulder region)	0.042	0.958	0.000
K41 Femoral hernia	0.041	0.959	0.000
M25.75 Osteophyte (Pelvic region and thigh)	0.039	0.961	0.000
J93.9 Pneumothorax, unspecified	0.000	0.963	0.037
J93 Pneumothorax	0.000	0.964	0.036
M25.73 Osteophyte (Forearm)	0.036	0.964	0.000
M25.77 Osteophyte (Ankle and foot)	0.035	0.965	0.000
C50.8 Overlapping lesion of breast	0.000	0.965	0.035
J93.1 Other spontaneous pneumothorax	0.000	0.966	0.034
M25.79 Osteophyte (Site unspecified)	0.034	0.966	0.000
J93.0 Spontaneous tension pneumothorax	0.000	0.968	0.032
M25.70 Osteophyte (Multiple sites)	0.032	0.968	0.000
J93.8 Other pneumothorax	0.000	0.968	0.032
M25.72 Osteophyte (Upper arm)	0.030	0.970	0.000
K41.4 Unilateral or unspecified femoral hernia, with gangrene	0.029	0.970	0.000
K41.2 Bilateral femoral hernia, without obstruction or gangrene	0.029	0.970	0.000
K41.1 Bilateral femoral hernia, with gangrene	0.029	0.970	0.000
K41.0 Bilateral femoral hernia, with obstruction, without gangrene	0.029	0.970	0.000
M25.74 Osteophyte (Hand)	0.025	0.975	0.000
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene	0.023	0.977	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.000	0.982	0.018
N48.1 Balanoposthitis	0.017	0.983	0.000
N48.4 Impotence of organic origin	0.016	0.984	0.000
D22.6 Melanocytic naevi of upper limb, including shoulder	0.000	0.984	0.016
M25.76 Osteophyte (Lower leg)	0.013	0.987	0.000
D63.1 Anaemia in other chronic diseases classified elsewhere	0.000	0.987	0.013
E04.2 Non-toxic multinodular goitre	0.000	0.987	0.013
J90-J94 Other diseases of pleura	0.000	0.989	0.011
J92 Pleural plaque	0.000	0.989	0.011
J92.0 Pleural plaque with presence of asbestos	0.000	0.989	0.011
J92.9 Pleural plaque without asbestos	0.000	0.991	0.009
D62 Acute posthaemorrhagic anaemia	0.000	0.992	0.008
D60-D64 Aplastic and other anaemias	0.000	0.992	0.008
J94 Other pleural conditions	0.000	0.992	0.008
N43.3 Hydrocele, unspecified	0.008	0.992	0.000
N18.4 Chronic kidney disease, stage 4	0.000	0.992	0.008
D63.8 Anaemia in other chronic diseases classified elsewhere	0.000	0.992	0.008
N48.6 Balanitis xerotica obliterans	0.007	0.993	0.000
N47 Redundant prepuce, phimosis and paraphimosis	0.007	0.993	0.000
J94.2 Haemothorax	0.000	0.993	0.007
I47.2 Ventricular tachycardia	0.007	0.993	0.000
J91 Pleural effusion in conditions classified elsewhere	0.000	0.993	0.007
Z87.2 Personal history of diseases of the skin and subcutaneous tissue	0.000	0.993	0.007
J94.9 Pleural condition, unspecified	0.000	0.994	0.006
J94.0 Chylous effusion	0.000	0.994	0.006
J94.1 Fibrothorax	0.000	0.994	0.006
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.000	0.994	0.006
D61 Other aplastic anaemias	0.000	0.994	0.006
D89.2 Hypergammaglobulinaemia, unspecified	0.006	0.994	0.000
Z85.3 Personal history of malignant neoplasm of breast	0.000	0.995	0.005
N18.5 Chronic kidney disease, stage 5	0.000	0.995	0.005
S06.80 Other intracranial injuries (without open intracranial wound)	0.005	0.995	0.000
R23.8 Other and unspecified skin changes	0.000	0.995	0.005
D61.0 Constitutional aplastic anaemia	0.000	0.995	0.005
N18 Chronic renal failure	0.000	0.995	0.005
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.005	0.995	0.000
D35.0 Adrenal gland	0.005	0.995	0.000
D60.8 Other acquired pure red cell aplasias	0.000	0.995	0.004
D60.1 Transient acquired pure red cell aplasia	0.000	0.995	0.004
D60.0 Chronic acquired pure red cell aplasia	0.000	0.995	0.004
D61.8 Other specified aplastic anaemias	0.000	0.995	0.004
D61.3 Idiopathic aplastic anaemia	0.000	0.995	0.004
D61.2 Aplastic anaemia due to other external agents	0.000	0.995	0.004
D61.1 Drug-induced aplastic anaemia	0.000	0.995	0.004
N18.2 Chronic kidney disease, stage 2	0.000	0.996	0.004
D89.0 Polyclonal hypergammaglobulinaemia	0.004	0.996	0.000
L98.0 Pyogenic granuloma	0.000	0.996	0.004
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.004	0.996	0.000
D60.9 Acquired pure red cell aplasia, unspecified	0.000	0.996	0.004
J94.8 Other specified pleural conditions	0.000	0.996	0.004
Z13.1 Special screening examination for diabetes mellitus	0.004	0.996	0.000
M25.31 Other instability of joint (Shoulder region)	0.004	0.996	0.000
N18.1 Chronic kidney disease, stage 1	0.000	0.996	0.004
S06.8 Other intracranial injuries	0.004	0.996	0.000
R23.4 Changes in skin texture	0.000	0.996	0.004
C44.5 Skin of trunk	0.000	0.996	0.004
N18.0 End-stage renal disease	0.000	0.996	0.004
S06.30 Focal brain injury (without open intracranial wound)	0.004	0.996	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.003	0.996	0.000
D89.3 Immune reconstitution syndrome	0.003	0.996	0.000
R23 Other skin changes	0.000	0.996	0.004
N18.8 Other chronic renal failure	0.000	0.996	0.003
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.003	0.997	0.000
D61.9 Aplastic anaemia, unspecified	0.000	0.997	0.003
D84.9 Immunodeficiency, unspecified	0.003	0.997	0.000
A04.8 Other specified bacterial intestinal infections	0.000	0.997	0.003
D89.9 Disorder involving the immune mechanism, unspecified	0.003	0.997	0.000
D22.7 Melanocytic naevi of lower limb, including hip	0.000	0.997	0.003
D89.1 Cryoglobulinaemia	0.003	0.997	0.000
O04.9 Complete or unspecified, without complication	0.000	0.997	0.003
D84 Other immunodeficiencies	0.003	0.997	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.003	0.997	0.000
D80-D89 Certain disorders involving the immune mechanism	0.003	0.997	0.000
S06.3 Focal brain injury	0.003	0.997	0.000
S06.81 Other intracranial injuries (with open intracranial wound)	0.003	0.997	0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.003	0.997	0.000
M22.8 Other disorders of patella	0.003	0.997	0.000
Q24.8 Other specified congenital malformations of heart	0.000	0.997	0.003
D80 Immunodeficiency with predominantly antibody defects	0.003	0.997	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.003	0.997	0.000
R23.0 Cyanosis	0.000	0.997	0.003
H25.0 Senile incipient cataract	0.003	0.997	0.000
N18.9 Chronic renal failure, unspecified	0.000	0.997	0.003
R23.1 Pallor	0.000	0.997	0.003
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.003	0.997	0.000
H54.7 Unspecified visual loss	0.003	0.997	0.000
I47.0 Reentry ventricular arrhythmia	0.003	0.997	0.000
A04.5 Campylobacter enteritis	0.000	0.997	0.003
S06 Intracranial injury	0.003	0.997	0.000
N32.8 Other specified disorders of bladder	0.003	0.997	0.000
O75.7 Vaginal delivery following previous Caesarean section	0.003	0.997	0.000
M25.3 Other instability of joint	0.003	0.997	0.000
D82 Immunodeficiency associated with other major defects	0.003	0.997	0.000
E14.3 With ophthalmic complications	0.000	0.997	0.003
I85.9 Oesophageal varices without bleeding	0.000	0.997	0.003
Q24.9 Congenital malformation of the heart, unspecified	0.000	0.997	0.003
R23.2 Flushing	0.000	0.997	0.003
I47 Paroxysmal tachycardia	0.003	0.997	0.000
D83 Common variable immunodeficiency	0.003	0.997	0.000
D64 Other anaemias	0.000	0.997	0.003
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.002	0.997	0.000
D84.8 Other specified immunodeficiencies	0.002	0.997	0.000
S06.5 Traumatic subdural haemorrhage	0.003	0.997	0.000
D81 Combined immunodeficiencies	0.002	0.997	0.000
M25.34 Other instability of joint (Hand)	0.003	0.997	0.000
S06.31 Focal brain injury (with open intracranial wound)	0.002	0.997	0.000
A04 Other bacterial intestinal infections	0.000	0.997	0.003
K63.8 Other specified diseases of intestine	0.003	0.997	0.000
Q24 Other congenital malformations of heart	0.000	0.997	0.002
I21.9 Acute myocardial infarction, unspecified	0.003	0.997	0.000
I49.0 Ventricular fibrillation and flutter	0.002	0.998	0.000
S06.4 Epidural haemorrhage	0.002	0.998	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.002	0.998	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.002	0.998	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.002	0.998	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.002	0.998	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.002	0.998	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.002	0.998	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.002	0.998	0.000
D82.1 Di George's syndrome	0.002	0.998	0.000
D84.1 Defects in the complement system	0.002	0.998	0.000
Q44.6 Cystic disease of liver	0.002	0.998	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.002	0.998	0.000
R07.1 Chest pain on breathing	0.002	0.998	0.000
R25.2 Cramp and spasm	0.000	0.998	0.002
E04 Other non-toxic goitre	0.000	0.998	0.002
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.002	0.998	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.002	0.998	0.000
H21.8 Other specified disorders of iris and ciliary body	0.002	0.998	0.000
I83.1 Varicose veins of lower extremities with inflammation	0.000	0.998	0.002
D83.9 Common variable immunodeficiency, unspecified	0.002	0.998	0.000
S06.7 Intracranial injury with prolonged coma	0.002	0.998	0.000
S06.1 Traumatic cerebral oedema	0.002	0.998	0.000
M25.39 Other instability of joint (Site unspecified)	0.002	0.998	0.000
M25.38 Other instability of joint (Other)	0.002	0.998	0.000
M25.35 Other instability of joint (Pelvic region and thigh)	0.002	0.998	0.000
M25.32 Other instability of joint (Upper arm)	0.002	0.998	0.000
M25.30 Other instability of joint (Multiple sites)	0.002	0.998	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.002	0.998	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.002	0.998	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.002	0.998	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.002	0.998	0.000
D82.2 Immunodeficiency with short-limbed stature	0.002	0.998	0.000
D82.0 Wiskott-Aldrich syndrome	0.002	0.998	0.000
H46 Optic neuritis	0.002	0.998	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.002	0.998	0.000
D83.8 Other common variable immunodeficiencies	0.002	0.998	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.002	0.998	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.002	0.998	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.002	0.998	0.000
M25.33 Other instability of joint (Forearm)	0.002	0.998	0.000
S06.40 Epidural haemorrhage (without open intracranial wound)	0.002	0.998	0.000
A04.9 Bacterial intestinal infection, unspecified	0.000	0.998	0.002
D64.4 Congenital dyserythropoietic anaemia	0.000	0.998	0.002
D64.3 Other sideroblastic anaemias	0.000	0.998	0.002
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.000	0.998	0.002
D64.1 Secondary sideroblastic anaemia due to disease	0.000	0.998	0.002
D12.7 Rectosigmoid junction	0.000	0.998	0.002
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.002	0.998	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.002	0.998	0.000
I47.9 Paroxysmal tachycardia, unspecified	0.002	0.998	0.000
Q24.0 Dextrocardia	0.000	0.998	0.002
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.002	0.998	0.000
D81.9 Combined immunodeficiency, unspecified	0.002	0.998	0.000
D81.8 Other combined immunodeficiencies	0.002	0.998	0.000
D81.7 Major histocompatibility complex class II deficiency	0.002	0.998	0.000
D81.6 Major histocompatibility complex class I deficiency	0.002	0.998	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.002	0.998	0.000
D81.4 Nezelof's syndrome	0.002	0.998	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.002	0.998	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.002	0.998	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.002	0.998	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.002	0.998	0.000
A04.6 Enteritis due to Yersinia enterocolitica	0.000	0.998	0.002
A04.3 Enterohaemorrhagic Escherichia coli infection	0.000	0.998	0.002
A04.2 Enteroinvasive Escherichia coli infection	0.000	0.998	0.002
A04.1 Enterotoxigenic Escherichia coli infection	0.000	0.998	0.002
A04.0 Enteropathogenic Escherichia coli infection	0.000	0.998	0.002
R23.3 Spontaneous ecchymoses	0.000	0.998	0.002
Z42.1 Follow-up care involving plastic surgery of breast	0.000	0.998	0.002
Q24.6 Congenital heart block	0.000	0.998	0.002
Q24.5 Malformation of coronary vessels	0.000	0.998	0.002
Q24.4 Congenital subaortic stenosis	0.000	0.998	0.002
Q24.3 Pulmonary infundibular stenosis	0.000	0.998	0.002
Q24.2 Cor triatriatum	0.000	0.998	0.002
Q24.1 Levocardia	0.000	0.998	0.002
M25 Other joint disorders, not elsewhere classified	0.002	0.998	0.000
A04.4 Other intestinal Escherichia coli infections	0.000	0.998	0.002
S06.41 Epidural haemorrhage (with open intracranial wound)	0.002	0.998	0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.002	0.998	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.002	0.998	0.000
S06.9 Intracranial injury, unspecified	0.002	0.998	0.000
D23.9 Skin, unspecified	0.002	0.998	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.002	0.998	0.000
M25.36 Other instability of joint (Lower leg)	0.002	0.998	0.000
R25.8 Other and unspecified abnormal involuntary movements	0.000	0.998	0.002
E04.8 Other specified non-toxic goitre	0.000	0.998	0.002
E04.0 Non-toxic diffuse goitre	0.000	0.998	0.002
G37.9 Demyelinating disease of central nervous system, unspecified	0.000	0.998	0.002
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified	0.000	0.998	0.002
I60 Subarachnoid haemorrhage	0.002	0.998	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.002	0.998	0.000
D64.8 Other specified anaemias	0.000	0.998	0.002
I25.5 Ischaemic cardiomyopathy	0.002	0.998	0.000
D64.0 Hereditary sideroblastic anaemia	0.000	0.998	0.002
R25 Abnormal involuntary movements	0.000	0.998	0.002
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.002	0.998	0.000
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.002	0.998	0.000
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.002	0.998	0.000
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.002	0.998	0.000
D22 Melanocytic naevi	0.000	0.998	0.002
F25.1 Schizoaffective disorder, depressive type	0.002	0.998	0.000
S06.2 Diffuse brain injury	0.002	0.998	0.000
S02.20 Fracture of nasal bones (closed)	0.002	0.998	0.000
M25.37 Other instability of joint (Ankle and foot)	0.002	0.998	0.000
M54.17 Radiculopathy (Lumbosacral region)	0.002	0.998	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.002	0.998	0.000
S06.0 Concussion	0.002	0.998	0.000
R25.1 Tremor, unspecified	0.000	0.998	0.002
A04.7 Enterocolitis due to Clostridium difficile	0.000	0.998	0.002
I22.9 Subsequent myocardial infarction of unspecified site	0.002	0.998	0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.002	0.998	0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.000	0.998	0.002
I60.4 Subarachnoid haemorrhage from basilar artery	0.002	0.998	0.000
M25.2 Flail joint	0.002	0.998	0.000
M25.1 Fistula of joint	0.002	0.998	0.000
Z97.0 Presence of artificial eye	0.002	0.998	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.002	0.998	0.000
M25.0 Haemarthrosis	0.002	0.998	0.000
Q44.5 Other congenital malformations of bile ducts	0.002	0.998	0.000
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.001	0.998	0.000
R25.3 Fasciculation	0.000	0.998	0.002
Q44.4 Choledochal cyst	0.002	0.998	0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.002	0.998	0.000
E04.1 Non-toxic single thyroid nodule	0.000	0.998	0.002
I78.1 Naevus, nonneoplastic	0.000	0.998	0.002
O75.9 Complication of labour and delivery, unspecified	0.002	0.998	0.000
O75.5 Delayed delivery after artificial rupture of membranes	0.002	0.998	0.000
O75.4 Other complications of obstetric surgery and procedures	0.002	0.998	0.000
O75.3 Other infection during labour	0.002	0.998	0.000
O75.1 Shock during or following labour and delivery	0.002	0.998	0.000
G54.0 Brachial plexus disorders	0.000	0.998	0.002
I60.5 Subarachnoid haemorrhage from vertebral artery	0.002	0.998	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.002	0.998	0.000
N17.0 Acute renal failure with tubular necrosis	0.000	0.998	0.002
Q38.7 Pharyngeal pouch	0.002	0.998	0.000
R25.0 Abnormal head movements	0.000	0.998	0.002
S06.21 Diffuse brain injury (with open intracranial wound)	0.001	0.998	0.000
D14.1 Larynx	0.000	0.998	0.002
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.002	0.998	0.000
Q44.7 Other congenital malformations of liver	0.001	0.998	0.000
Q44.3 Congenital stenosis and stricture of bile ducts	0.001	0.998	0.000
Q44.2 Atresia of bile ducts	0.001	0.998	0.000
Q44.1 Other congenital malformations of gallbladder	0.001	0.998	0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder	0.001	0.998	0.000
R30.9 Painful micturition, unspecified	0.002	0.998	0.000
Y48.3 Local anaesthetics	0.000	0.998	0.002
S06.01 Concussion (with open intracranial wound)	0.001	0.998	0.000
D86.1 Sarcoidosis of lymph nodes	0.002	0.998	0.000
M40.26 Other and unspecified kyphosis (Lumbar region)	0.000	0.998	0.001
M48.00 Spinal stenosis (Multiple sites in spine)	0.002	0.998	0.000
M25.09 Haemarthrosis (Site unspecified)	0.001	0.998	0.000
M25.08 Haemarthrosis (Other)	0.001	0.998	0.000
M25.07 Haemarthrosis (Ankle and foot)	0.001	0.998	0.000
M25.05 Haemarthrosis (Pelvic region and thigh)	0.001	0.998	0.000
M25.04 Haemarthrosis (Hand)	0.001	0.998	0.000
M25.03 Haemarthrosis (Forearm)	0.001	0.998	0.000
M25.02 Haemarthrosis (Upper arm)	0.001	0.998	0.000
M25.01 Haemarthrosis (Shoulder region)	0.001	0.998	0.000
M25.00 Haemarthrosis (Multiple sites)	0.001	0.998	0.000
M25.19 Fistula of joint (Site unspecified)	0.001	0.998	0.000
M25.18 Fistula of joint (Other)	0.001	0.998	0.000
M25.17 Fistula of joint (Ankle and foot)	0.001	0.998	0.000
M25.16 Fistula of joint (Lower leg)	0.001	0.998	0.000
M25.15 Fistula of joint (Pelvic region and thigh)	0.001	0.998	0.000
M25.14 Fistula of joint (Hand)	0.001	0.998	0.000
M25.13 Fistula of joint (Forearm)	0.001	0.998	0.000
M25.12 Fistula of joint (Upper arm)	0.001	0.998	0.000
M25.11 Fistula of joint (Shoulder region)	0.001	0.998	0.000
M25.10 Fistula of joint (Multiple sites)	0.001	0.998	0.000
M25.29 Flail joint (Site unspecified)	0.001	0.998	0.000
M25.28 Flail joint (Other)	0.001	0.998	0.000
M25.27 Flail joint (Ankle and foot)	0.001	0.998	0.000
M25.26 Flail joint (Lower leg)	0.001	0.998	0.000
M25.25 Flail joint (Pelvic region and thigh)	0.001	0.998	0.000
M25.24 Flail joint (Hand)	0.001	0.998	0.000
M25.23 Flail joint (Forearm)	0.001	0.998	0.000
M25.22 Flail joint (Upper arm)	0.001	0.998	0.000
M25.21 Flail joint (Shoulder region)	0.001	0.998	0.000
M25.20 Flail joint (Multiple sites)	0.001	0.998	0.000
M40.24 Other and unspecified kyphosis (Thoracic region)	0.000	0.998	0.001
C18.2 Ascending colon	0.000	0.998	0.002
D22.0 Melanocytic naevi of lip	0.000	0.998	0.002
D48.5 Skin	0.002	0.998	0.000
F25.0 Schizoaffective disorder, manic type	0.001	0.998	0.000
M25.06 Haemarthrosis (Lower leg)	0.001	0.998	0.000
M25.44 Effusion of joint (Hand)	0.001	0.998	0.000
M25.40 Effusion of joint (Multiple sites)	0.001	0.998	0.000
M25.41 Effusion of joint (Shoulder region)	0.001	0.998	0.000
K05.3 Chronic periodontitis	0.002	0.998	0.000
Q85.0 Neurofibromatosis (nonmalignant)	0.001	0.998	0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.001	0.999	0.000
M19.13 Post-traumatic arthrosis of other joints (Forearm)	0.000	0.999	0.001
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.001	0.999	0.000
M23.3 Other meniscus derangements	0.001	0.999	0.000
R27.0 Ataxia, unspecified	0.000	0.999	0.001
S02.2 Fracture of nasal bones	0.001	0.999	0.000
T92.2 Sequelae of fracture at wrist and hand level	0.000	0.999	0.001
Y49.5 Other antipsychotics and neuroleptics	0.000	0.999	0.001
D86 Sarcoidosis	0.001	0.999	0.000
O04 Medical abortion	0.000	0.999	0.001
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.000	0.999	0.001
I78.0 Hereditary haemorrhagic telangiectasia	0.000	0.999	0.001
M25.4 Effusion of joint	0.001	0.999	0.000
M40.2 Other and unspecified kyphosis	0.000	0.999	0.001
Q66.8 Other congenital deformities of feet	0.001	0.999	0.000
Y48.4 Anaesthetic, unspecified	0.000	0.999	0.001
F02.0 Dementia in Pick's disease	0.001	0.999	0.000
K35.3 Acute appendicitis with localized peritonitis	0.000	0.999	0.001
Z73.9 Problem related to life-management difficulty, unspecified	0.001	0.999	0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.000	0.999	0.001
M40.29 Other and unspecified kyphosis (Site unspecified)	0.000	0.999	0.001
S02.00 Fracture of vault of skull (closed)	0.001	0.999	0.000
J69.0 Pneumonitis due to food and vomit	0.001	0.999	0.000
L56.9 Acute skin change due to ultraviolet radiation, unspecified	0.001	0.999	0.000
G60.8 Other hereditary and idiopathic neuropathies	0.001	0.999	0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.000	0.999	0.001
D22.2 Melanocytic naevi of ear and external auricular canal	0.000	0.999	0.001
I46.9 Cardiac arrest, unspecified	0.000	0.999	0.001
Q68.8 Other specified congenital musculoskeletal deformities	0.001	0.999	0.000
F25 Schizoaffective disorders	0.001	0.999	0.000
G35 Multiple sclerosis	0.000	0.999	0.001
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.999	0.001
I84.4 External haemorrhoids with other complications	0.001	0.999	0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.001	0.999	0.000
T84.2 Mechanical complication of internal fixation device of other bones	0.001	0.999	0.000
R81 Glycosuria	0.001	0.999	0.000
M19.11 Post-traumatic arthrosis of other joints (Shoulder region)	0.000	0.999	0.001
O75.8 Other specified complications of labour and delivery	0.001	0.999	0.000
M70.56 Other bursitis of knee-Lower Leg	0.001	0.999	0.000
A16.9 Respiratory tuberculosis unspecified, without mention of bacteriological or histological confirmation	0.000	0.999	0.001
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.000	0.999	0.001
F25.2 Schizoaffective disorder, mixed type	0.001	0.999	0.000
H21.4 Pupillary membranes	0.001	0.999	0.000
O04.8 Complete or unspecified, with other and unspecified complications	0.000	0.999	0.001
X49.9 Unspecified place	0.000	0.999	0.001
G37 Other demyelinating diseases of central nervous system	0.000	0.999	0.001
M23.37 Other meniscus derangements-Capsular lig	0.001	0.999	0.000
M25.49 Effusion of joint (Site unspecified)	0.001	0.999	0.000
M25.48 Effusion of joint (Other)	0.001	0.999	0.000
M25.42 Effusion of joint (Upper arm)	0.001	0.999	0.000
M40.28 Other and unspecified kyphosis (Sacral and sacrococcygeal region)	0.000	0.999	0.001
M40.27 Other and unspecified kyphosis (Lumbosacral region)	0.000	0.999	0.001
M40.25 Other and unspecified kyphosis (Thoracolumbar region)	0.000	0.999	0.001
M40.23 Other and unspecified kyphosis (Cervicothoracic region)	0.000	0.999	0.001
M40.22 Other and unspecified kyphosis (Cervical region)	0.000	0.999	0.001
M40.21 Other and unspecified kyphosis (Occipito-atlanto-axial region)	0.000	0.999	0.001
M40.20 Other and unspecified kyphosis (Multiple sites in spine)	0.000	0.999	0.001
H21.9 Disorder of iris and ciliary body, unspecified	0.001	0.999	0.000
I88.9 Nonspecific lymphadenitis, unspecified	0.001	0.999	0.000
O04.7 Complete or unspecified, complicated by embolism	0.000	0.999	0.001
O04.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.000	0.999	0.001
O04.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.000	0.999	0.001
O04.3 Incomplete, with other and unspecified complications	0.000	0.999	0.001
O04.2 Incomplete, complicated by embolism	0.000	0.999	0.001
O04.0 Incomplete, complicated by genital tract and pelvic infection	0.000	0.999	0.001
T93.2 Sequelae of other fractures of lower limb	0.001	0.999	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.001	0.999	0.000
N17-N19 Renal failure	0.000	0.999	0.001
A02.0 Salmonella gastro-enteritis	0.001	0.999	0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.001	0.999	0.000
S02.21 Fracture of nasal bones (open)	0.001	0.999	0.000
K85.9 Acute pancreatitis, unspecified	0.000	0.999	0.001
M70.46 Prepatellar bursitis-Lower Leg	0.000	0.999	0.001
S02.70 Multiple fractures involving skull and facial bones (closed)	0.001	0.999	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.001	0.999	0.000
F25.8 Other schizoaffective disorders	0.001	0.999	0.000
G61.8 Other inflammatory polyneuropathies	0.001	0.999	0.000
H53.9 Visual disturbance, unspecified	0.001	0.999	0.000
J45.0 Predominantly allergic asthma	0.001	0.999	0.000
Q66.0 Talipes equinovarus	0.001	0.999	0.000
R82.9 Other and unspecified abnormal finding in urine	0.001	0.999	0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)	0.001	0.999	0.000
A16.2 Tuberculosis of lung, without mention of bacteriological or histological confirmation	0.000	0.999	0.001
C83.0 Small cell (diffuse)	0.000	0.999	0.001
J32.8 Other chronic sinusitis	0.001	0.999	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.000	0.999	0.001
O04.1 Incomplete, complicated by delayed or excessive haemorrhage	0.000	0.999	0.001
O75.2 Pyrexia during labour, not elsewhere classified	0.001	0.999	0.000
R41.2 Retrograde amnesia	0.000	0.999	0.001
G37.8 Other specified demyelinating diseases of central nervous system	0.000	0.999	0.001
G37.5 Concentric sclerosis [Balo]	0.000	0.999	0.001
G37.4 Subacute necrotising myelitis	0.000	0.999	0.001
G37.2 Central pontine myelinolysis	0.000	0.999	0.001
G37.1 Central demyelination of corpus callosum	0.000	0.999	0.001
G37.0 Diffuse sclerosis	0.000	0.999	0.001
I60.8 Other subarachnoid haemorrhage	0.001	0.999	0.000
N85.2 Hypertrophy of uterus	0.000	0.999	0.001
S02.0 Fracture of vault of skull	0.001	0.999	0.000
D86.8 Sarcoidosis of other and combined sites	0.001	0.999	0.000
D86.3 Sarcoidosis of skin	0.001	0.999	0.000
F25.9 Schizoaffective disorder, unspecified	0.001	0.999	0.000
H57.1 Ocular pain	0.001	0.999	0.000
I62.1 Nontraumatic extradural haemorrhage	0.001	0.999	0.000
Q38.8 Other congenital malformations of pharynx	0.001	0.999	0.000
Q38.5 Congenital malformations of palate, not elsewhere classified	0.001	0.999	0.000
Q38.4 Congenital malformations of salivary glands and ducts	0.001	0.999	0.000
Q38.3 Other congenital malformations of tongue	0.001	0.999	0.000
Q38.2 Macroglossia	0.001	0.999	0.000
Q38.0 Congenital malformations of lips, not elsewhere classified	0.001	0.999	0.000
Q66.7 Pes cavus	0.001	0.999	0.000
D35 Benign neoplasm of other and unspecified endocrine glands	0.001	0.999	0.000
H21 Other disorders of iris and ciliary body	0.001	0.999	0.000
M19.14 Post-traumatic arthrosis of other joints (Hand)	0.000	0.999	0.001
M90.78 Fracture of bone in neoplastic disease (Other)	0.001	0.999	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations