TreeWAS – Variant ID: rs1127354

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.906	0.094
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.906	0.094
T43.2 Other and unspecified antidepressants	0.000	0.906	0.094
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.911	0.089
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.916	0.084
T40.2 Other opioids	0.000	0.916	0.084
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.917	0.083
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.918	0.082
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.922	0.077
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.927	0.073
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.927	0.073
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.928	0.072
T42.4 Benzodiazepines	0.000	0.928	0.072
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.929	0.071
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.930	0.070
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.930	0.070
T40.4 Other synthetic narcotics	0.000	0.931	0.069
T39.0 Salicylates	0.000	0.931	0.069
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.931	0.069
T43.9 Psychotropic drug, unspecified	0.000	0.932	0.068
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.932	0.068
T43.6 Psychostimulants with abuse potential	0.000	0.932	0.068
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.932	0.068
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.932	0.068
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.932	0.067
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.932	0.067
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.932	0.067
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.932	0.067
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.932	0.067
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.932	0.068
T40.6 Other and unspecified narcotics	0.000	0.935	0.065
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.936	0.064
T40.8 Lysergide [LSD]	0.000	0.936	0.064
T40.7 Cannabis (derivatives)	0.000	0.936	0.064
T40.5 Cocaine	0.000	0.936	0.064
T40.3 Methadone	0.000	0.936	0.064
T40.1 Heroin	0.000	0.936	0.064
T40.0 Opium	0.000	0.936	0.064
T36 Poisoning by systemic antibiotics	0.000	0.936	0.063
T50.8 Diagnostic agents	0.000	0.939	0.061
T50.7 Analeptics and opioid receptor antagonists	0.000	0.939	0.061
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.939	0.061
T50.5 Appetite depressants	0.000	0.939	0.061
T50.4 Drugs affecting uric acid metabolism	0.000	0.939	0.061
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.939	0.061
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.939	0.061
T50.1 Loop [high-ceiling] diuretics	0.000	0.939	0.061
T50.0 Mineralocorticoids and their antagonists	0.000	0.939	0.061
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.940	0.060
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.940	0.060
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.940	0.060
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.940	0.060
T42.3 Barbiturates	0.000	0.940	0.060
T42.2 Succinimides and oxazolidinediones	0.000	0.940	0.060
T42.1 Iminostilbenes	0.000	0.940	0.060
T42.0 Hydantoin derivatives	0.000	0.940	0.060
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.941	0.059
T39.4 Antirheumatics, not elsewhere classified	0.000	0.941	0.059
T39.2 Pyrazolone derivatives	0.000	0.941	0.059
T45.0 Antiallergic and antiemetic drugs	0.000	0.945	0.055
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.946	0.054
T39.1 4-Aminophenol derivatives	0.000	0.947	0.053
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.947	0.052
T38.9 Other and unspecified hormone antagonists	0.000	0.949	0.051
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.949	0.051
T38.7 Androgens and anabolic congeners	0.000	0.949	0.051
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.949	0.051
T38.5 Other oestrogens and progestogens	0.000	0.949	0.051
T38.4 Oral contraceptives	0.000	0.949	0.051
T38.2 Antithyroid drugs	0.000	0.949	0.051
T38.1 Thyroid hormones and substitutes	0.000	0.949	0.051
T38.0 Glucocorticoids and synthetic analogues	0.000	0.949	0.051
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.949	0.050
T45.8 Other primarily systemic and haematological agents	0.000	0.949	0.050
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.949	0.050
T45.6 Fibrinolysis-affecting drugs	0.000	0.949	0.050
T45.4 Iron and its compounds	0.000	0.949	0.050
T45.3 Enzymes, not elsewhere classified	0.000	0.949	0.050
T45.2 Vitamins, not elsewhere classified	0.000	0.949	0.050
T45.1 Antineoplastic and immunosuppressive drugs	0.000	0.949	0.050
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.950	0.050
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.950	0.050
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.950	0.050
T46.7 Peripheral vasodilators	0.000	0.950	0.050
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.950	0.050
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.950	0.050
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.950	0.050
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.950	0.050
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.950	0.050
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.951	0.049
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.951	0.049
T37.5 Antiviral drugs	0.000	0.951	0.049
T37.4 Anthelminthics	0.000	0.951	0.049
T37.3 Other antiprotozoal drugs	0.000	0.951	0.049
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.951	0.049
T37.1 Antimycobacterial drugs	0.000	0.951	0.049
T37.0 Sulphonamides	0.000	0.951	0.049
T41.5 Therapeutic gases	0.000	0.951	0.049
T41.4 Anaesthetic, unspecified	0.000	0.951	0.049
T41.3 Local anaesthetics	0.000	0.951	0.049
T41.2 Other and unspecified general anaesthetics	0.000	0.951	0.049
T41.1 Intravenous anaesthetics	0.000	0.951	0.049
T41.0 Inhaled anaesthetics	0.000	0.951	0.049
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.951	0.049
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.951	0.049
T47.7 Emetics	0.000	0.951	0.049
T47.6 Antidiarrhoeal drugs	0.000	0.951	0.049
T47.5 Digestants	0.000	0.951	0.049
T47.4 Other laxatives	0.000	0.951	0.049
T47.3 Saline and osmotic laxatives	0.000	0.951	0.049
T47.2 Stimulant laxatives	0.000	0.951	0.049
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.951	0.049
T47.0 Histamine H(2)-receptor antagonists	0.000	0.951	0.049
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.951	0.049
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.951	0.049
T48.5 Anti-common-cold drugs	0.000	0.951	0.049
T48.4 Expectorants	0.000	0.951	0.049
T48.3 Antitussives	0.000	0.951	0.049
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.951	0.049
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.951	0.049
T48.0 Oxytocic drugs	0.000	0.951	0.049
T49.9 Topical agent, unspecified	0.000	0.951	0.049
T49.8 Other topical agents	0.000	0.951	0.049
T49.7 Dental drugs, topically applied	0.000	0.951	0.049
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.951	0.049
T49.5 Ophthalmological drugs and preparations	0.000	0.951	0.049
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.951	0.049
T49.3 Emollients, demulcents and protectants	0.000	0.951	0.049
T49.2 Local astringents and local detergents	0.000	0.951	0.049
T49.1 Antipruritics	0.000	0.951	0.049
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.951	0.049
T46.1 Calcium-channel blockers	0.000	0.952	0.048
T45.5 Anticoagulants	0.000	0.953	0.047
T36.9 Systemic antibiotic, unspecified	0.000	0.954	0.046
T36.8 Other systemic antibiotics	0.000	0.954	0.046
T36.7 Antifungal antibiotics, systemically used	0.000	0.954	0.046
T36.6 Rifamycins	0.000	0.954	0.046
T36.5 Aminoglycosides	0.000	0.954	0.046
T36.4 Tetracyclines	0.000	0.954	0.046
T36.3 Macrolides	0.000	0.954	0.046
T36.2 Chloramphenicol group	0.000	0.954	0.046
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.954	0.046
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.957	0.043
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.957	0.043
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.957	0.043
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.957	0.043
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.957	0.043
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.957	0.043
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.957	0.043
T44.0 Anticholinesterase agents	0.000	0.957	0.043
T36.0 Penicillins	0.000	0.958	0.041
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.959	0.041
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.961	0.039
Z90.1 Acquired absence of breast(s)	0.018	0.982	0.000
M41.96 Scoliosis, unspecified (Lumbar region)	0.016	0.984	0.000
Z80.4 Family history of malignant neoplasm of genital organs	0.000	0.986	0.014
G93 Other disorders of brain	0.013	0.987	0.000
M41.9 Scoliosis, unspecified	0.013	0.987	0.000
G90-G99 Other disorders of the nervous system	0.012	0.988	0.000
G99.2 Myelopathy in diseases classified elsewhere	0.012	0.988	0.000
G99 Other disorders of nervous system in diseases classified elsewhere	0.012	0.988	0.000
G93.8 Other specified disorders of brain	0.012	0.988	0.000
G93.6 Cerebral oedema	0.012	0.988	0.000
G94 Other disorders of brain in diseases classified elsewhere	0.012	0.988	0.000
M41.99 Scoliosis, unspecified (Site unspecified)	0.011	0.988	0.000
G93.9 Disorder of brain, unspecified	0.011	0.989	0.000
G94.2 Hydrocephalus in other diseases classified elsewhere	0.011	0.989	0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.011	0.989	0.000
I51.9 Heart disease, unspecified	0.000	0.989	0.010
G95 Other diseases of spinal cord	0.010	0.990	0.000
G90 Disorders of autonomic nervous system	0.010	0.990	0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.010	0.990	0.000
G93.0 Cerebral cysts	0.010	0.990	0.000
G93.5 Compression of brain	0.010	0.990	0.000
G93.2 Benign intracranial hypertension	0.010	0.990	0.000
G93.7 Reye's syndrome	0.009	0.990	0.000
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.009	0.990	0.000
M41.97 Scoliosis, unspecified (Lumbosacral region)	0.009	0.990	0.000
M41.94 Scoliosis, unspecified (Thoracic region)	0.009	0.990	0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)	0.009	0.990	0.000
M41.92 Scoliosis, unspecified (Cervical region)	0.009	0.990	0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)	0.009	0.990	0.000
M41.90 Scoliosis, unspecified (Multiple sites in spine)	0.009	0.990	0.000
G97.8 Other postprocedural disorders of nervous system	0.009	0.991	0.000
G98 Other disorders of nervous system, not elsewhere classified	0.009	0.991	0.000
G92 Toxic encephalopathy	0.009	0.991	0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere	0.009	0.991	0.000
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere	0.009	0.991	0.000
G93.4 Encephalopathy, unspecified	0.009	0.991	0.000
G93.3 Postviral fatigue syndrome	0.009	0.991	0.000
G97.1 Other reaction to spinal and lumbar puncture	0.009	0.991	0.000
G94.8 Other specified disorders of brain in diseases classified elsewhere	0.008	0.991	0.000
G94.1 Hydrocephalus in neoplastic disease	0.008	0.991	0.000
G94.0 Hydrocephalus in infectious and parasitic diseases classified elsewhere	0.008	0.991	0.000
G95.9 Disease of spinal cord, unspecified	0.008	0.991	0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases	0.008	0.991	0.000
G93.1 Anoxic brain damage, not elsewhere classified	0.008	0.992	0.000
G95.1 Vascular myelopathies	0.008	0.992	0.000
G90.0 Idiopathic peripheral autonomic neuropathy	0.008	0.992	0.000
G97.9 Postprocedural disorder of nervous system, unspecified	0.008	0.992	0.000
G97.2 Intracranial hypotension following ventricular shunting	0.008	0.992	0.000
G97.0 Cerebrospinal fluid leak from spinal puncture	0.008	0.992	0.000
G95.8 Other specified diseases of spinal cord	0.008	0.992	0.000
G96 Other disorders of central nervous system	0.007	0.992	0.000
G90.3 Multisystem degeneration	0.007	0.992	0.000
G90.9 Disorder of autonomic nervous system, unspecified	0.007	0.992	0.000
G95.0 Syringomyelia and syringobulbia	0.007	0.992	0.000
G90.8 Other disorders of autonomic nervous system	0.007	0.993	0.000
G90.4 Autonomic dysreflexia	0.007	0.993	0.000
G90.1 Familial dysautonomia [Riley-Day]	0.007	0.993	0.000
G90.2 Horner's syndrome	0.007	0.993	0.000
M41 Scoliosis	0.006	0.993	0.000
G91 Hydrocephalus	0.006	0.994	0.000
G96.9 Disorder of central nervous system, unspecified	0.006	0.994	0.000
G96.8 Other specified disorders of central nervous system	0.006	0.994	0.000
G96.1 Disorders of meninges, not elsewhere classified	0.005	0.994	0.000
G95.2 Cord compression, unspecified	0.005	0.995	0.000
M41.8 Other forms of scoliosis	0.005	0.995	0.000
M41.5 Other secondary scoliosis	0.005	0.995	0.000
M41.4 Neuromuscular scoliosis	0.005	0.995	0.000
M41.3 Thoracogenic scoliosis	0.005	0.995	0.000
M41.2 Other idiopathic scoliosis	0.005	0.995	0.000
M41.1 Juvenile idiopathic scoliosis	0.005	0.995	0.000
M41.0 Infantile idiopathic scoliosis	0.005	0.995	0.000
G91.8 Other hydrocephalus	0.004	0.995	0.000
G91.3 Posttraumatic hydrocephalus, unspecified	0.004	0.995	0.000
G91.2 Normal-pressure hydrocephalus	0.004	0.995	0.000
G91.0 Communicating hydrocephalus	0.004	0.995	0.000
G96.0 Cerebrospinal fluid leak	0.004	0.996	0.000
G91.1 Obstructive hydrocephalus	0.004	0.996	0.000
G30-G32 Other degenerative diseases of the nervous system	0.004	0.996	0.000
G30 Alzheimer's disease	0.004	0.996	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.004	0.996	0.000
G82.1 Spastic paraplegia	0.004	0.996	0.000
Z09.9 Follow-up examination after unspecified treatment for other conditions	0.000	0.996	0.004
G82 Paraplegia and tetraplegia	0.004	0.996	0.000
Chapter VI Diseases of the nervous system	0.004	0.996	0.000
S82.40 Fracture of fibula alone (closed)	0.004	0.996	0.000
M41.09 Infantile idiopathic scoliosis (Site unspecified)	0.004	0.996	0.000
M41.08 Infantile idiopathic scoliosis (Sacral and sacrococcygeal region)	0.004	0.996	0.000
M41.07 Infantile idiopathic scoliosis (Lumbosacral region)	0.004	0.996	0.000
M41.06 Infantile idiopathic scoliosis (Lumbar region)	0.004	0.996	0.000
M41.05 Infantile idiopathic scoliosis (Thoracolumbar region)	0.004	0.996	0.000
M41.04 Infantile idiopathic scoliosis (Thoracic region)	0.004	0.996	0.000
M41.03 Infantile idiopathic scoliosis (Cervicothoracic region)	0.004	0.996	0.000
M41.02 Infantile idiopathic scoliosis (Cervical region)	0.004	0.996	0.000
M41.01 Infantile idiopathic scoliosis (Occipito-atlanto-axial region)	0.004	0.996	0.000
M41.00 Infantile idiopathic scoliosis (Multiple sites in spine)	0.004	0.996	0.000
M41.19 Juvenile idiopathic scoliosis (Site unspecified)	0.004	0.996	0.000
M41.18 Juvenile idiopathic scoliosis (Sacral and sacrococcygeal region)	0.004	0.996	0.000
M41.17 Juvenile idiopathic scoliosis (Lumbosacral region)	0.004	0.996	0.000
M41.16 Juvenile idiopathic scoliosis (Lumbar region)	0.004	0.996	0.000
M41.15 Juvenile idiopathic scoliosis (Thoracolumbar region)	0.004	0.996	0.000
M41.14 Juvenile idiopathic scoliosis (Thoracic region)	0.004	0.996	0.000
M41.13 Juvenile idiopathic scoliosis (Cervicothoracic region)	0.004	0.996	0.000
M41.12 Juvenile idiopathic scoliosis (Cervical region)	0.004	0.996	0.000
M41.11 Juvenile idiopathic scoliosis (Occipito-atlanto-axial region)	0.004	0.996	0.000
M41.10 Juvenile idiopathic scoliosis (Multiple sites in spine)	0.004	0.996	0.000
M41.29 Other idiopathic scoliosis (Site unspecified)	0.004	0.996	0.000
M41.28 Other idiopathic scoliosis (Sacral and sacrococcygeal region)	0.004	0.996	0.000
M41.27 Other idiopathic scoliosis (Lumbosacral region)	0.004	0.996	0.000
M41.26 Other idiopathic scoliosis (Lumbar region)	0.004	0.996	0.000
M41.25 Other idiopathic scoliosis (Thoracolumbar region)	0.004	0.996	0.000
M41.24 Other idiopathic scoliosis (Thoracic region)	0.004	0.996	0.000
M41.23 Other idiopathic scoliosis (Cervicothoracic region)	0.004	0.996	0.000
M41.22 Other idiopathic scoliosis (Cervical region)	0.004	0.996	0.000
M41.21 Other idiopathic scoliosis (Occipito-atlanto-axial region)	0.004	0.996	0.000
M41.20 Other idiopathic scoliosis (Multiple sites in spine)	0.004	0.996	0.000
M41.39 Thoracogenic scoliosis-Site unspe	0.004	0.996	0.000
M41.38 Thoracogenic scoliosis-Sacral/sacrococ	0.004	0.996	0.000
M41.37 Thoracogenic scoliosis-Lumbosacral	0.004	0.996	0.000
M41.36 Thoracogenic scoliosis-Lumbar	0.004	0.996	0.000
M41.35 Thoracogenic scoliosis (Thoracolumbar region)	0.004	0.996	0.000
M41.34 Thoracogenic scoliosis (Thoracic region)	0.004	0.996	0.000
M41.33 Thoracogenic scoliosis (Cervicothoracic region)	0.004	0.996	0.000
M41.32 Thoracogenic scoliosis-Cervical	0.004	0.996	0.000
M41.31 Thoracogenic scoliosis-Occipit-atl-axl	0.004	0.996	0.000
M41.30 Thoracogenic scoliosis (Multiple sites in spine)	0.004	0.996	0.000
M41.49 Neuromuscular scoliosis (Site unspecified)	0.004	0.996	0.000
M41.48 Neuromuscular scoliosis (Sacral and sacrococcygeal region)	0.004	0.996	0.000
M41.47 Neuromuscular scoliosis (Lumbosacral region)	0.004	0.996	0.000
M41.46 Neuromuscular scoliosis (Lumbar region)	0.004	0.996	0.000
M41.45 Neuromuscular scoliosis (Thoracolumbar region)	0.004	0.996	0.000
M41.44 Neuromuscular scoliosis (Thoracic region)	0.004	0.996	0.000
M41.43 Neuromuscular scoliosis (Cervicothoracic region)	0.004	0.996	0.000
M41.42 Neuromuscular scoliosis (Cervical region)	0.004	0.996	0.000
M41.41 Neuromuscular scoliosis (Occipito-atlanto-axial region)	0.004	0.996	0.000
M41.40 Neuromuscular scoliosis (Multiple sites in spine)	0.004	0.996	0.000
M41.59 Other secondary scoliosis (Site unspecified)	0.004	0.996	0.000
M41.58 Other secondary scoliosis (Sacral and sacrococcygeal region)	0.004	0.996	0.000
M41.57 Other secondary scoliosis (Lumbosacral region)	0.004	0.996	0.000
M41.56 Other secondary scoliosis (Lumbar region)	0.004	0.996	0.000
M41.55 Other secondary scoliosis (Thoracolumbar region)	0.004	0.996	0.000
M41.54 Other secondary scoliosis (Thoracic region)	0.004	0.996	0.000
M41.53 Other secondary scoliosis (Cervicothoracic region)	0.004	0.996	0.000
M41.52 Other secondary scoliosis (Cervical region)	0.004	0.996	0.000
M41.51 Other secondary scoliosis (Occipito-atlanto-axial region)	0.004	0.996	0.000
M41.50 Other secondary scoliosis (Multiple sites in spine)	0.004	0.996	0.000
M41.89 Other forms of scoliosis (Site unspecified)	0.004	0.996	0.000
M41.88 Other forms of scoliosis (Sacral and sacrococcygeal region)	0.004	0.996	0.000
M41.87 Other forms of scoliosis (Lumbosacral region)	0.004	0.996	0.000
M41.86 Other forms of scoliosis (Lumbar region)	0.004	0.996	0.000
M41.85 Other forms of scoliosis (Thoracolumbar region)	0.004	0.996	0.000
M41.84 Other forms of scoliosis (Thoracic region)	0.004	0.996	0.000
M41.83 Other forms of scoliosis (Cervicothoracic region)	0.004	0.996	0.000
M41.82 Other forms of scoliosis (Cervical region)	0.004	0.996	0.000
M41.81 Other forms of scoliosis (Occipito-atlanto-axial region)	0.004	0.996	0.000
M41.80 Other forms of scoliosis (Multiple sites in spine)	0.004	0.996	0.000
G30.9 Alzheimer's disease, unspecified	0.004	0.996	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.004	0.996	0.000
G30.8 Other Alzheimer's disease	0.004	0.996	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.004	0.996	0.000
G82.5 Tetraplegia, unspecified	0.003	0.996	0.000
G82.4 Spastic tetraplegia	0.003	0.996	0.000
D61.9 Aplastic anaemia, unspecified	0.003	0.997	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.003	0.997	0.000
D12.5 Sigmoid colon	0.000	0.997	0.003
G37 Other demyelinating diseases of central nervous system	0.003	0.997	0.000
K56.6 Other and unspecified intestinal obstruction	0.000	0.997	0.003
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.003	0.997	0.000
Z13.9 Special screening examination, unspecified	0.003	0.997	0.000
G30.1 Alzheimer's disease with late onset	0.003	0.997	0.000
G30.0 Alzheimer's disease with early onset	0.003	0.997	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.003	0.997	0.000
M35.3 Polymyalgia rheumatica	0.000	0.997	0.003
G51.0 Bell's palsy	0.003	0.997	0.000
G82.3 Flaccid tetraplegia	0.003	0.997	0.000
G82.0 Flaccid paraplegia	0.003	0.997	0.000
N60.8 Other benign mammary dysplasias	0.003	0.997	0.000
G51 Facial nerve disorders	0.003	0.997	0.000
G70-G73 Diseases of myoneural junction and muscle	0.003	0.997	0.000
G31.1 Senile degeneration of brain, not elsewhere classified	0.003	0.997	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.003	0.997	0.000
G31.2 Degeneration of nervous system due to alcohol	0.003	0.997	0.000
G35 Multiple sclerosis	0.003	0.997	0.000
G37.8 Other specified demyelinating diseases of central nervous system	0.003	0.997	0.000
G36 Other acute disseminated demyelination	0.003	0.997	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.003	0.997	0.000
G31.0 Circumscribed brain atrophy	0.003	0.997	0.000
G91.9 Hydrocephalus, unspecified	0.002	0.997	0.001
Z52.4 Kidney donor	0.003	0.997	0.000
N60 Benign mammary dysplasia	0.003	0.997	0.000
G50-G59 Nerve, nerve root and plexus disorders	0.003	0.997	0.000
G51.9 Disorder of facial nerve, unspecified	0.003	0.997	0.000
N60.3 Fibrosclerosis of breast	0.003	0.997	0.000
G82.2 Paraplegia, unspecified	0.003	0.997	0.000
G37.5 Concentric sclerosis [Balo]	0.002	0.997	0.000
G37.4 Subacute necrotising myelitis	0.002	0.997	0.000
G37.2 Central pontine myelinolysis	0.002	0.997	0.000
G37.1 Central demyelination of corpus callosum	0.002	0.997	0.000
G37.0 Diffuse sclerosis	0.002	0.997	0.000
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere	0.002	0.997	0.000
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere	0.002	0.997	0.000
H73.8 Other specified disorders of tympanic membrane	0.000	0.997	0.003
N60.2 Fibroadenosis of breast	0.003	0.997	0.000
D12.4 Descending colon	0.000	0.997	0.003
K65.9 Peritonitis, unspecified	0.000	0.997	0.003
K65.0 Acute peritonitis	0.000	0.997	0.003
G53 Cranial nerve disorders in diseases classified elsewhere	0.002	0.997	0.000
G83 Other paralytic syndromes	0.002	0.997	0.000
G06 Intracranial and intraspinal abscess and granuloma	0.002	0.997	0.000
E29.1 Testicular hypofunction	0.002	0.997	0.000
G20-G26 Extrapyramidal and movement disorders	0.002	0.997	0.000
N60.1 Diffuse cystic mastopathy	0.002	0.997	0.000
N60.0 Solitary cyst of breast	0.002	0.997	0.000
G70 Myasthenia gravis and other myoneural disorders	0.002	0.997	0.000
G52 Disorders of other cranial nerves	0.002	0.998	0.000
G51.8 Other disorders of facial nerve	0.002	0.998	0.000
G51.4 Facial myokymia	0.002	0.998	0.000
G51.3 Clonic hemifacial spasm	0.002	0.998	0.000
G51.2 Melkersson's syndrome	0.002	0.998	0.000
G51.1 Geniculate ganglionitis	0.002	0.998	0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere	0.002	0.998	0.000
G80 Infantile cerebral palsy	0.002	0.998	0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.002	0.998	0.000
G71 Primary disorders of muscles	0.002	0.998	0.000
G53.0 Postzoster neuralgia	0.002	0.998	0.000
G83.8 Other specified paralytic syndromes	0.002	0.998	0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.002	0.998	0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
G00 Bacterial meningitis, not elsewhere classified	0.002	0.998	0.000
G09 Sequelae of inflammatory diseases of central nervous system	0.002	0.998	0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.002	0.998	0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere	0.002	0.998	0.000
G01 Meningitis in bacterial diseases classified elsewhere	0.002	0.998	0.000
D12.3 Transverse colon	0.000	0.998	0.002
G72 Other myopathies	0.002	0.998	0.000
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere	0.002	0.998	0.000
G14 Postpolio syndrome	0.002	0.998	0.000
G10 Huntington's disease	0.002	0.998	0.000
G25.8 Other specified extrapyramidal and movement disorders	0.002	0.998	0.000
G36.9 Acute disseminated demyelination, unspecified	0.002	0.998	0.000
G36.8 Other specified acute disseminated demyelination	0.002	0.998	0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]	0.002	0.998	0.000
G36.0 Neuromyelitis optica [Devic]	0.002	0.998	0.000
G11 Hereditary ataxia	0.002	0.998	0.000
G52.8 Disorders of other specified cranial nerves	0.002	0.998	0.000
M50.0 Cervical disk disorder with myelopathy	0.002	0.998	0.000
N60.9 Benign mammary dysplasia, unspecified	0.002	0.998	0.000
S82.4 Fracture of fibula alone	0.002	0.998	0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.000	0.998	0.002
G03 Meningitis due to other and unspecified causes	0.002	0.998	0.000
G25 Other extrapyramidal and movement disorders	0.002	0.998	0.000
G50 Disorders of trigeminal nerve	0.002	0.998	0.000
G06.2 Extradural and subdural abscess, unspecified	0.002	0.998	0.000
H00.1 Chalazion	0.000	0.998	0.002
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.000	0.998	0.002
G56.8 Other mononeuropathies of upper limb	0.002	0.998	0.000
K65 Peritonitis	0.000	0.998	0.002
Z80 Family history of malignant neoplasm	0.000	0.998	0.002
G04 Encephalitis, myelitis and encephalomyelitis	0.002	0.998	0.000
G31.8 Other specified degenerative diseases of nervous system	0.002	0.998	0.000
G71.3 Mitochondrial myopathy, not elsewhere classified	0.002	0.998	0.000
N60.4 Mammary duct ectasia	0.002	0.998	0.000
G56 Mononeuropathies of upper limb	0.002	0.998	0.000
D12.6 Colon, unspecified	0.000	0.998	0.002
G53.8 Other cranial nerve disorders in other diseases classified elsewhere	0.002	0.998	0.000
G53.3 Multiple cranial nerve palsies in neoplastic disease	0.002	0.998	0.000
G53.2 Multiple cranial nerve palsies in sarcoidosis	0.002	0.998	0.000
G53.1 Multiple cranial nerve palsies in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
G83.9 Paralytic syndrome, unspecified	0.002	0.998	0.000
G83.5 Locked-in syndrome	0.002	0.998	0.000
G83.3 Monoplegia, unspecified	0.002	0.998	0.000
G83.0 Diplegia of upper limbs	0.002	0.998	0.000
G58 Other mononeuropathies	0.002	0.998	0.000
G06.1 Intraspinal abscess and granuloma	0.002	0.998	0.000
G06.0 Intracranial abscess and granuloma	0.002	0.998	0.000
D12.0 Caecum	0.000	0.998	0.002
G70.0 Myasthenia gravis	0.002	0.998	0.000
G83.2 Monoplegia of upper limb	0.002	0.998	0.000
G12 Spinal muscular atrophy and related syndromes	0.002	0.998	0.000
G23 Other degenerative diseases of basal ganglia	0.002	0.998	0.000
G21 Secondary Parkinsonism	0.002	0.998	0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.002	0.998	0.000
G22 Parkinsonism in diseases classified elsewhere	0.002	0.998	0.000
G56.3 Lesion of radial nerve	0.002	0.998	0.000
G70.9 Myoneural disorder, unspecified	0.002	0.998	0.000
G70.8 Other specified myoneural disorders	0.002	0.998	0.000
G70.2 Congenital and developmental myasthenia	0.002	0.998	0.000
G70.1 Toxic myoneural disorders	0.002	0.998	0.000
G52.9 Cranial nerve disorder, unspecified	0.002	0.998	0.000
G52.7 Disorders of multiple cranial nerves	0.002	0.998	0.000
G52.3 Disorders of hypoglossal nerve	0.002	0.998	0.000
G52.2 Disorders of vagus nerve	0.002	0.998	0.000
G52.1 Disorders of glossopharyngeal nerve	0.002	0.998	0.000
G52.0 Disorders of olfactory nerve	0.002	0.998	0.000
G73.7 Myopathy other diseases classified elsewhere	0.002	0.998	0.000
G73.6 Myopathy in metabolic diseases	0.002	0.998	0.000
G73.5 Myopathy in endocrine diseases	0.002	0.998	0.000
G73.4 Myopathy in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
G73.3 Myasthenic syndromes in other diseases classified elsewhere	0.002	0.998	0.000
G73.2 Other myasthenic syndromes in neoplastic disease	0.002	0.998	0.000
G73.1 Eaton-Lambert syndrome	0.002	0.998	0.000
G73.0 Myasthenic syndromes in endocrine diseases	0.002	0.998	0.000
G80.8 Other infantile cerebral palsy	0.002	0.998	0.000
G80.4 Ataxic cerebral palsy	0.002	0.998	0.000
G80.3 Dyskinetic cerebral palsy	0.002	0.998	0.000
G80.2 Infantile hemiplegia	0.002	0.998	0.000
G80.1 Spastic diplegia	0.002	0.998	0.000
G80.0 Spastic cerebral palsy	0.002	0.998	0.000
J92.0 Pleural plaque with presence of asbestos	0.000	0.998	0.002
G71.9 Primary disorder of muscle, unspecified	0.002	0.998	0.000
G71.8 Other primary disorders of muscles	0.002	0.998	0.000
G71.2 Congenital myopathies	0.002	0.998	0.000
G00.9 Bacterial meningitis, unspecified	0.002	0.998	0.000
G00.8 Other bacterial meningitis	0.002	0.998	0.000
G00.3 Staphylococcal meningitis	0.002	0.998	0.000
G00.2 Streptococcal meningitis	0.002	0.998	0.000
G00.1 Pneumococcal meningitis	0.002	0.998	0.000
G00.0 Haemophilus meningitis	0.002	0.998	0.000
G02.8 Meningitis in other specified infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
G02.1 Meningitis in mycoses	0.002	0.998	0.000
G02.0 Meningitis in viral diseases classified elsewhere	0.002	0.998	0.000
G05.8 Encephalitis, myelitis and encephalomyelitis in other diseases classified elsewhere	0.002	0.998	0.000
G05.2 Encephalitis, myelitis and encephalomyelitis in other infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere	0.002	0.998	0.000
G05.0 Encephalitis, myelitis and encephalomyelitis in bacterial diseases classified elsewhere	0.002	0.998	0.000
G25.3 Myoclonus	0.002	0.998	0.000
Z80.9 Family history of malignant neoplasm, unspecified	0.000	0.998	0.002
G72.8 Other specified myopathies	0.002	0.998	0.000
G72.4 Inflammatory myopathy, not elsewhere classified	0.002	0.998	0.000
G72.3 Periodic paralysis	0.002	0.998	0.000
G72.2 Myopathy due to other toxic agents	0.002	0.998	0.000
G72.1 Alcoholic myopathy	0.002	0.998	0.000
G72.0 Drug-induced myopathy	0.002	0.998	0.000
K65.8 Other peritonitis	0.000	0.998	0.002
G13.8 Systemic atrophy primarily affecting central nervous system in other diseases classified elsewhere	0.002	0.998	0.000
G13.2 Systemic atrophy primarily affecting central nervous system in myxoedema	0.002	0.998	0.000
G13.1 Other systemic atrophy primarily affecting central nervous system in neoplastic disease	0.002	0.998	0.000
G13.0 Paraneoplastic neuromyopathy and neuropathy	0.002	0.998	0.000
G58.7 Mononeuritis multiplex	0.002	0.998	0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung	0.000	0.998	0.002
G24 Dystonia	0.002	0.998	0.000
G11.8 Other hereditary ataxias	0.002	0.998	0.000
G11.4 Hereditary spastic paraplegia	0.002	0.998	0.000
G11.3 Cerebellar ataxia with defective DNA repair	0.002	0.998	0.000
G11.2 Late-onset cerebellar ataxia	0.002	0.998	0.000
G11.1 Early-onset cerebellar ataxia	0.002	0.998	0.000
G11.0 Congenital nonprogressive ataxia	0.002	0.998	0.000
G71.0 Muscular dystrophy	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations