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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs113512172
log Bayes Factor = 16.4938
Chromosome 21   position 32,718,685  (GRCh37) Explore rs113512172 on Ensembl!
Variant rs113512172 is part of Cluster X0150

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
I50 Heart failure
0.997 0.003 0.000
Chapter X Diseases of the respiratory system
0.994 0.006 0.000
J40-J47 Chronic lower respiratory diseases
0.990 0.010 0.000
I50.0 Congestive heart failure
0.989 0.011 0.000
I49 Other cardiac arrhythmias
0.988 0.012 0.000
J44 Other chronic obstructive pulmonary disease
0.988 0.012 0.000
M15-M19 Arthrosis
0.987 0.013 0.000
Z93 Artificial opening status
0.985 0.015 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.984 0.016 0.000
M16 Coxarthrosis [arthrosis of hip]
0.983 0.017 0.000
M16.9 Coxarthrosis, unspecified
0.982 0.018 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.980 0.020 0.000
Chapter I Certain infectious and parasitic diseases
0.978 0.022 0.000
I49.9 Cardiac arrhythmia, unspecified
0.977 0.023 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.975 0.025 0.000
Chapter VI Diseases of the nervous system
0.975 0.025 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.974 0.026 0.000
I20-I25 Ischaemic heart diseases
0.971 0.029 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.970 0.030 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.964 0.036 0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances
0.959 0.041 0.000
I25 Chronic ischaemic heart disease
0.958 0.042 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.952 0.048 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.949 0.051 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.949 0.051 0.000
R04 Haemorrhage from respiratory passages
0.948 0.052 0.000
J09-J18 Influenza and pneumonia
0.948 0.052 0.000
M50-M54 Other dorsopathies
0.947 0.053 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.942 0.058 0.000
Z03.8 Observation for other suspected diseases and conditions
0.939 0.061 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.937 0.063 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.936 0.064 0.000
R04.2 Haemoptysis
0.936 0.064 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.933 0.067 0.000
Z12 Special screening examination for neoplasms
0.930 0.070 0.000
I35 Nonrheumatic aortic valve disorders
0.929 0.071 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.929 0.071 0.000
Z93.2 Ileostomy status
0.928 0.072 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.924 0.076 0.000
I50.1 Left ventricular failure
0.917 0.083 0.000
B25-B34 Other viral diseases
0.912 0.088 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.908 0.092 0.000
M65-M68 Disorders of synovium and tendon
0.908 0.092 0.000
B35-B49 Mycoses
0.907 0.093 0.000
Z91.5 Personal history of self-harm
0.904 0.096 0.000
Z95.2 Presence of prosthetic heart valve
0.900 0.100 0.000
Z93.1 Gastrostomy status
0.897 0.103 0.000
Chapter VIII Diseases of the ear and mastoid process
0.896 0.104 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.895 0.105 0.000
Z80 Family history of malignant neoplasm
0.894 0.106 0.000
Z12.1 Special screening examination for neoplasm of intestinal tract
0.893 0.107 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.889 0.111 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.887 0.113 0.000
Z04 Examination and observation for other reasons
0.887 0.113 0.000
D60-D64 Aplastic and other anaemias
0.884 0.116 0.000
Z60 Problems related to social environment
0.883 0.117 0.000
Z93.0 Tracheostomy status
0.881 0.119 0.000
R25 Abnormal involuntary movements
0.880 0.120 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.879 0.121 0.000
E70-E90 Metabolic disorders
0.879 0.121 0.000
R06 Abnormalities of breathing
0.875 0.125 0.000
L91 Hypertrophic disorders of skin
0.872 0.128 0.000
Z80.0 Family history of malignant neoplasm of digestive organs
0.868 0.132 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.868 0.132 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.868 0.132 0.000
B34 Viral infection of unspecified site
0.865 0.135 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.862 0.138 0.000
J43 Emphysema
0.856 0.144 0.000
L89 Decubitus ulcer
0.856 0.144 0.000
D64 Other anaemias
0.856 0.144 0.000
Z87 Personal history of other diseases and conditions
0.854 0.146 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.853 0.147 0.000
M50 Cervical disk disorders
0.852 0.148 0.000
Z60.2 Living alone
0.848 0.152 0.000
B37 Candidiasis
0.846 0.154 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.844 0.156 0.000
I49.0 Ventricular fibrillation and flutter
0.842 0.158 0.000
Z88.5 Personal history of allergy to narcotic agent
0.840 0.160 0.000
G20-G26 Extrapyramidal and movement disorders
0.840 0.160 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.840 0.160 0.000
R06.8 Other and unspecified abnormalities of breathing
0.838 0.162 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.838 0.162 0.000
D64.9 Anaemia, unspecified
0.836 0.164 0.000
O00-O08 Pregnancy with abortive outcome
0.835 0.165 0.000
I35.0 Aortic (valve) stenosis
0.834 0.166 0.000
B34.9 Viral infection, unspecified
0.831 0.169 0.000
I51 Complications and ill-defined descriptions of heart disease
0.830 0.170 0.000
L82 Seborrhoeic keratosis
0.826 0.174 0.000
R02 Gangrene, not elsewhere classified
0.826 0.174 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.824 0.176 0.000
L91.8 Other hypertrophic disorders of skin
0.824 0.176 0.000
G35 Multiple sclerosis
0.824 0.176 0.000
I49.5 Sick sinus syndrome
0.822 0.177 0.000
M67 Other disorders of synovium and tendon
0.822 0.178 0.000
B95-B98 Bacterial, viral and other infectious agents
0.821 0.179 0.000
I47 Paroxysmal tachycardia
0.821 0.179 0.000
Z03.4 Observation for suspected myocardial infarction
0.820 0.180 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.817 0.183 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.812 0.188 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.808 0.192 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.806 0.194 0.000
G90-G99 Other disorders of the nervous system
0.804 0.196 0.000
Chapter XIV Diseases of the genitourinary system
0.803 0.197 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.801 0.199 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.801 0.199 0.000
I22 Subsequent myocardial infarction
0.800 0.200 0.000
J20-J22 Other acute lower respiratory infections
0.800 0.200 0.000
L84 Corns and callosities
0.799 0.201 0.000
R26 Abnormalities of gait and mobility
0.799 0.201 0.000
M05-M14 Inflammatory polyarthropathies
0.797 0.203 0.000
I46 Cardiac arrest
0.797 0.203 0.000
B37.8 Candidiasis of other sites
0.797 0.203 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.796 0.204 0.000
L89.1 Stage II decubitus ulcer
0.794 0.206 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.793 0.206 0.000
Z36 Antenatal screening
0.793 0.207 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.791 0.209 0.000
J60-J70 Lung diseases due to external agents
0.791 0.209 0.000
I42 Cardiomyopathy
0.789 0.211 0.000
I34 Nonrheumatic mitral valve disorders
0.788 0.211 0.000
M86-M90 Other osteopathies
0.788 0.212 0.000
Z90.2 Acquired absence of lung [part of]
0.788 0.212 0.000
E87.6 Hypokalaemia
0.787 0.213 0.000
Chapter XXII Codes for special purposes
0.786 0.214 0.000
R25.1 Tremor, unspecified
0.785 0.215 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.783 0.217 0.000
Z04.8 Examination and observation for other specified reasons
0.782 0.218 0.000
I31 Other diseases of pericardium
0.779 0.221 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.778 0.222 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.777 0.223 0.000
Z97 Presence of other devices
0.777 0.223 0.000
M51 Other intervertebral disk disorders
0.776 0.223 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.776 0.224 0.000
E78.0 Pure hypercholesterolaemia
0.776 0.224 0.000
I20 Angina pectoris
0.776 0.224 0.000
M54 Dorsalgia
0.775 0.225 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.775 0.225 0.000
R25.2 Cramp and spasm
0.772 0.228 0.000
Z84 Family history of other conditions
0.771 0.229 0.000
H60-H62 Diseases of external ear
0.768 0.232 0.000
Z87.0 Personal history of diseases of the respiratory system
0.768 0.232 0.000
Z95.4 Presence of other heart-valve replacement
0.765 0.235 0.000
M60-M63 Disorders of muscles
0.765 0.235 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.764 0.236 0.000
Z88.6 Personal history of allergy to analgesic agent
0.764 0.236 0.000
B15-B19 Viral hepatitis
0.763 0.236 0.000
M20-M25 Other joint disorders
0.761 0.239 0.000
J43.9 Emphysema, unspecified
0.761 0.239 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.760 0.240 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.757 0.243 0.000
Z36.9 Antenatal screening, unspecified
0.757 0.243 0.000
E87.2 Acidosis
0.755 0.245 0.000
Z87.2 Personal history of diseases of the skin and subcutaneous tissue
0.754 0.246 0.000
J18 Pneumonia, organism unspecified
0.754 0.246 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.754 0.246 0.000
O04 Medical abortion
0.753 0.247 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.752 0.248 0.000
Chapter V Mental and behavioural disorders
0.749 0.251 0.000
G25 Other extrapyramidal and movement disorders
0.744 0.256 0.000
M67.8 Other specified disorders of synovium and tendon
0.743 0.256 0.000
I45 Other conduction disorders
0.743 0.257 0.000
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue
0.741 0.259 0.000
I38 Endocarditis, valve unspecified
0.740 0.260 0.000
I10-I15 Hypertensive diseases
0.740 0.260 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.739 0.261 0.000
M50.2 Other cervical disk displacement
0.738 0.262 0.000
M40-M43 Deforming dorsopathies
0.737 0.263 0.000
R06.0 Dyspnoea
0.737 0.263 0.000
N40-N51 Diseases of male genital organs
0.735 0.265 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.734 0.266 0.000
I50.9 Heart failure, unspecified
0.734 0.266 0.000
M06 Other rheumatoid arthritis
0.733 0.267 0.000
R80 Isolated proteinuria
0.733 0.267 0.000
M80-M85 Disorders of bone density and structure
0.732 0.268 0.000
N25-N29 Other disorders of kidney and ureter
0.731 0.269 0.000
Z93.6 Other artificial openings of urinary tract status
0.731 0.269 0.000
J46 Status asthmaticus
0.731 0.269 0.000
I25.5 Ischaemic cardiomyopathy
0.730 0.270 0.000
Z96 Presence of other functional implants
0.729 0.271 0.000
E87.5 Hyperkalaemia
0.729 0.271 0.000
Z90.3 Acquired absence of part of stomach
0.728 0.272 0.000
M45-M49 Spondylopathies
0.727 0.273 0.000
H90-H95 Other disorders of ear
0.726 0.274 0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen
0.724 0.276 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.720 0.280 0.000
J40 Bronchitis, not specified as acute or chronic
0.718 0.282 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.718 0.282 0.000
I35.1 Aortic (valve) insufficiency
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I36 Nonrheumatic tricuspid valve disorders
0.717 0.283 0.000
I33 Acute and subacute endocarditis
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I30 Acute pericarditis
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Z81 Family history of mental and behavioural disorders
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.716 0.284 0.000
G30-G32 Other degenerative diseases of the nervous system
0.716 0.284 0.000
I05-I09 Chronic rheumatic heart diseases
0.716 0.284 0.000
M91-M94 Chondropathies
0.714 0.286 0.000
J10 Influenza due to identified influenza virus
0.712 0.288 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.712 0.288 0.000
M65 Synovitis and tenosynovitis
0.711 0.289 0.000
G93 Other disorders of brain
0.710 0.290 0.000
J41 Simple and mucopurulent chronic bronchitis
0.710 0.290 0.000
R07 Pain in throat and chest
0.710 0.290 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.709 0.291 0.000
Z89 Acquired absence of limb
0.709 0.291 0.000
R47-R49 Symptoms and signs involving speech and voice
0.709 0.291 0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung
0.709 0.291 0.000
I49.2 Junctional premature depolarisation
0.709 0.291 0.000
I49.1 Atrial premature depolarisation
0.709 0.291 0.000
Z03.3 Observation for suspected nervous system disorder
0.708 0.292 0.000
M15 Polyarthrosis
0.707 0.293 0.000
I20.9 Angina pectoris, unspecified
0.707 0.293 0.000
Z93.9 Artificial opening status, unspecified
0.706 0.294 0.000
Z93.8 Other artificial opening status
0.706 0.294 0.000
Z93.5 Cystostomy status
0.706 0.294 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.706 0.294 0.000
D80-D89 Certain disorders involving the immune mechanism
0.706 0.294 0.000
J42 Unspecified chronic bronchitis
0.705 0.294 0.000
Z91.8 Personal history of other specified risk-factors, not elsewhere classified
0.705 0.295 0.000
Z91.7 Personal history of female genital mutilation
0.705 0.295 0.000
Z91.4 Personal history of psychological trauma, not elsewhere classified
0.705 0.295 0.000
Z91.3 Personal history of unhealthy sleep-wake schedule
0.705 0.295 0.000
Z91.2 Personal history of poor personal hygiene
0.705 0.295 0.000
M16.7 Other secondary coxarthrosis
0.705 0.295 0.000
M16.6 Other secondary coxarthrosis, bilateral
0.705 0.295 0.000
M16.5 Other posttraumatic coxarthrosis
0.705 0.295 0.000
M16.4 Posttraumatic coxarthrosis, bilateral
0.705 0.295 0.000
M16.3 Other dysplastic coxarthrosis
0.705 0.295 0.000
M16.2 Coxarthrosis resulting from dysplasia, bilateral
0.705 0.295 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.704 0.296 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.704 0.296 0.000
R04.0 Epistaxis
0.703 0.297 0.000
B99-B99 Other infectious diseases
0.701 0.299 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.701 0.299 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.701 0.299 0.000
B65-B83 Helminthiases
0.701 0.299 0.000
B50-B64 Protozoal diseases
0.701 0.299 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.701 0.299 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.701 0.299 0.000
A80-A89 Viral infections of the central nervous system
0.701 0.299 0.000
A75-A79 Rickettsioses
0.701 0.299 0.000
A70-A74 Other diseases caused by chlamydiae
0.701 0.299 0.000
A65-A69 Other spirochaetal diseases
0.701 0.299 0.000
A20-A28 Certain zoonotic bacterial diseases
0.701 0.299 0.000
A15-A19 Tuberculosis
0.701 0.299 0.000
O85-O92 Complications predominantly related to the puerperium
0.701 0.299 0.000
D62 Acute posthaemorrhagic anaemia
0.700 0.300 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.700 0.300 0.000
Z10 Routine general health check-up of defined subpopulation
0.699 0.301 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.699 0.301 0.000
B44 Aspergillosis
0.697 0.303 0.000
L90 Atrophic disorders of skin
0.697 0.303 0.000
I23 Certain current complications following acute myocardial infarction
0.696 0.304 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.695 0.304 0.000
Z04.1 Examination and observation following transport accident
0.695 0.305 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.695 0.305 0.000
Z57 Occupational exposure to risk-factors
0.695 0.305 0.000
O04.9 Complete or unspecified, without complication
0.694 0.306 0.000
E50-E64 Other nutritional deficiencies
0.694 0.306 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.694 0.306 0.000
H80-H83 Diseases of inner ear
0.693 0.307 0.000
I51.8 Other ill-defined heart diseases
0.693 0.307 0.000
Z95.0 Presence of cardiac pacemaker
0.693 0.307 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.692 0.308 0.000
M06.9 Rheumatoid arthritis, unspecified
0.692 0.308 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.692 0.308 0.000
Z12.0 Special screening examination for neoplasm of stomach
0.691 0.308 0.000
E87.0 Hyperosmolality and hypernatraemia
0.691 0.309 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.691 0.309 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.690 0.310 0.000
M50.1 Cervical disk disorder with radiculopathy
0.689 0.311 0.000
G70-G73 Diseases of myoneural junction and muscle
0.688 0.312 0.000
M53 Other dorsopathies, not elsewhere classified
0.687 0.313 0.000
I25.6 Silent myocardial ischaemia
0.686 0.313 0.000
I25.4 Coronary artery aneurysm
0.686 0.313 0.000
I25.3 Aneurysm of heart
0.686 0.313 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.686 0.313 0.000
R45 Symptoms and signs involving emotional state
0.686 0.314 0.000
R82 Other abnormal findings in urine
0.686 0.314 0.000
I47.2 Ventricular tachycardia
0.685 0.315 0.000
Z95.3 Presence of xenogenic heart valve
0.684 0.316 0.000
Z03.6 Observation for suspected toxic effect from ingested substance
0.683 0.317 0.000
Z03.2 Observation for suspected mental and behavioural disorders
0.683 0.317 0.000
Z03.0 Observation for suspected tuberculosis
0.683 0.317 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.681 0.319 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.681 0.319 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.680 0.320 0.000
Z12.8 Special screening examination for neoplasm of other sites
0.680 0.320 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.680 0.320 0.000
R04.9 Haemorrhage from respiratory passages, unspecified
0.680 0.320 0.000
R04.8 Haemorrhage from other sites in respiratory passages
0.680 0.320 0.000
R04.1 Haemorrhage from throat
0.680 0.320 0.000
J17 Pneumonia in diseases classified elsewhere
0.679 0.320 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.679 0.320 0.000
J12 Viral pneumonia, not elsewhere classified
0.679 0.320 0.000
J11 Influenza, virus not identified
0.679 0.320 0.000
J14 Pneumonia due to Haemophilus influenzae
0.679 0.320 0.000
J09 Influenza due to certain identified influenza virus
0.679 0.320 0.000
Z04.9 Examination and observation for unspecified reason
0.679 0.321 0.000
Z03.1 Observation for suspected malignant neoplasm
0.678 0.322 0.000
I12 Hypertensive renal disease
0.678 0.322 0.000
B37.3 Candidiasis of vulva and vagina
0.678 0.322 0.000
G12 Spinal muscular atrophy and related syndromes
0.676 0.324 0.000
Z95.1 Presence of aortocoronary bypass graft
0.675 0.325 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.674 0.326 0.000
J15.1 Pneumonia due to Pseudomonas
0.674 0.326 0.000
L10-L14 Bullous disorders
0.672 0.328 0.000
O16 Unspecified maternal hypertension
0.672 0.328 0.000
I77 Other disorders of arteries and arterioles
0.672 0.328 0.000
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium
0.671 0.329 0.000
Z65 Problems related to other psychosocial circumstances
0.669 0.331 0.000
Z64 Problems related to certain psychosocial circumstances
0.669 0.331 0.000
Z62 Other problems related to upbringing
0.669 0.331 0.000
Z61 Problems related to negative life events in childhood
0.669 0.331 0.000
Z59 Problems related to housing and economic circumstances
0.669 0.331 0.000
Z58 Problems related to physical environment
0.669 0.331 0.000
Z56 Problems related to employment and unemployment
0.669 0.331 0.000
Z55 Problems related to education and literacy
0.669 0.331 0.000
O02 Other abnormal products of conception
0.668 0.332 0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems
0.668 0.332 0.000
L89.2 Stage III decubitus ulcer
0.667 0.332 0.000
Z12.9 Special screening examination for neoplasm, unspecified
0.667 0.333 0.000
Z12.6 Special screening examination for neoplasm of bladder
0.667 0.333 0.000
Z12.5 Special screening examination for neoplasm of prostate
0.667 0.333 0.000
Z12.4 Special screening examination for neoplasm of cervix
0.667 0.333 0.000
Z12.3 Special screening examination for neoplasm of breast
0.667 0.333 0.000
Z12.2 Special screening examination for neoplasm of respiratory organs
0.667 0.333 0.000
I35.9 Aortic valve disorder, unspecified
0.666 0.334 0.000
I35.8 Other aortic valve disorders
0.666 0.334 0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.666 0.334 0.000
B07 Viral warts
0.666 0.334 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.666 0.334 0.000
L94 Other localised connective tissue disorders
0.666 0.334 0.000
L93 Lupus erythematosus
0.666 0.334 0.000
L87 Transepidermal elimination disorders
0.666 0.334 0.000
L88 Pyoderma gangrenosum
0.666 0.334 0.000
L86 Keratoderma in diseases classified elsewhere
0.666 0.334 0.000
L83 Acanthosis nigricans
0.666 0.334 0.000
L80 Vitiligo
0.666 0.334 0.000
M18 Arthrosis of first carpometacarpal joint
0.665 0.335 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.665 0.335 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.665 0.335 0.000
R27 Other lack of coordination
0.664 0.336 0.000
O36 Maternal care for other known or suspected foetal problems
0.664 0.336 0.000
M22 Disorders of patella
0.663 0.337 0.000
D55-D59 Haemolytic anaemias
0.663 0.337 0.000
G25.0 Essential tremor
0.662 0.338 0.000
M54.4 Lumbago with sciatica
0.662 0.338 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.661 0.339 0.000
J22 Unspecified acute lower respiratory infection
0.660 0.340 0.000
L91.0 Keloid scar
0.659 0.341 0.000
Z88.2 Personal history of allergy to sulphonamides
0.659 0.341 0.000
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods
0.658 0.342 0.000
Z35 Supervision of high-risk pregnancy
0.658 0.342 0.000
M51.2 Other specified intervertebral disk displacement
0.658 0.342 0.000
E78.4 Other hyperlipidaemia
0.657 0.343 0.000
H60 Otitis externa
0.655 0.345 0.000
B33 Other viral diseases, not elsewhere classified
0.654 0.346 0.000
B30 Viral conjunctivitis
0.654 0.346 0.000
B27 Infectious mononucleosis
0.654 0.346 0.000
B26 Mumps
0.654 0.346 0.000
B25 Cytomegaloviral disease
0.654 0.346 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.653 0.347 0.000
N99-N99 Other disorders of the genitourinary system
0.651 0.349 0.000
J15.4 Pneumonia due to other streptococci
0.651 0.349 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.651 0.349 0.000
M66 Spontaneous rupture of synovium and tendon
0.651 0.349 0.000
R09.3 Abnormal sputum
0.651 0.349 0.000
I51.9 Heart disease, unspecified
0.651 0.349 0.000
B48 Other mycoses, not elsewhere classified
0.650 0.349 0.000
B47 Mycetoma
0.650 0.349 0.000
B46 Zygomycosis
0.650 0.349 0.000
B45 Cryptococcosis
0.650 0.349 0.000
B43 Chromomycosis and phaeomycotic abscess
0.650 0.349 0.000
B42 Sporotrichosis
0.650 0.349 0.000
B41 Paracoccidioidomycosis
0.650 0.349 0.000
B40 Blastomycosis
0.650 0.349 0.000
B39 Histoplasmosis
0.650 0.349 0.000
B38 Coccidioidomycosis
0.650 0.349 0.000
B36 Other superficial mycoses
0.650 0.349 0.000
B35 Dermatophytosis
0.650 0.349 0.000
B49 Unspecified mycosis
0.650 0.349 0.000
I49.4 Other and unspecified premature depolarisation
0.650 0.349 0.000
R09.2 Respiratory arrest
0.650 0.350 0.000
D61 Other aplastic anaemias
0.650 0.350 0.000
Z04.3 Examination and observation following other accident
0.650 0.350 0.000
N40 Hyperplasia of prostate
0.649 0.351 0.000
I34.1 Mitral (valve) prolapse
0.648 0.352 0.000
Z80.8 Family history of malignant neoplasm of other organs or systems
0.648 0.352 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.646 0.354 0.000
O41 Other disorders of amniotic fluid and membranes
0.645 0.355 0.000
Z63 Other problems related to primary support group, including family circumstances
0.645 0.355 0.000
I49.8 Other specified cardiac arrhythmias
0.645 0.355 0.000
R09.1 Pleurisy
0.644 0.356 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.644 0.356 0.000
N17-N19 Renal failure
0.644 0.356 0.000
O48 Prolonged pregnancy
0.643 0.357 0.000
I24 Other acute ischaemic heart diseases
0.643 0.357 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.643 0.357 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.642 0.357 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.642 0.358 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.642 0.358 0.000
J95-J99 Other diseases of the respiratory system
0.642 0.358 0.000
E40-E46 Malnutrition
0.642 0.358 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.642 0.358 0.000
N10-N16 Renal tubulo-interstitial diseases
0.641 0.359 0.000
M67.1 Other contracture of tendon (sheath)
0.641 0.359 0.000
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues
0.641 0.359 0.000
Z80.6 Family history of leukaemia
0.641 0.359 0.000
Z80.5 Family history of malignant neoplasm of urinary tract
0.641 0.359 0.000
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs
0.641 0.359 0.000
I70 Atherosclerosis
0.641 0.359 0.000
B37.9 Candidiasis, unspecified
0.639 0.361 0.000
M50.0 Cervical disk disorder with myelopathy
0.639 0.361 0.000
I31.9 Disease of pericardium, unspecified
0.639 0.361 0.000
N00-N08 Glomerular diseases
0.639 0.361 0.000
G37 Other demyelinating diseases of central nervous system
0.638 0.361 0.000
F60-F69 Disorders of adult personality and behaviour
0.638 0.362 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.638 0.362 0.000
E87.7 Fluid overload
0.637 0.363 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.637 0.363 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.637 0.363 0.000
R25.8 Other and unspecified abnormal involuntary movements
0.637 0.363 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.637 0.363 0.000
G36 Other acute disseminated demyelination
0.636 0.364 0.000
Z04.6 General psychiatric examination, requested by authority
0.636 0.364 0.000
Z04.5 Examination and observation following other inflicted injury
0.636 0.364 0.000
Z04.4 Examination and observation following alleged rape and seduction
0.636 0.364 0.000
Z04.2 Examination and observation following work accident
0.636 0.364 0.000
Z04.0 Blood-alcohol and blood-drug test
0.636 0.364 0.000
L81 Other disorders of pigmentation
0.636 0.364 0.000
Z94 Transplanted organ and tissue status
0.634 0.365 0.000
I46.9 Cardiac arrest, unspecified
0.634 0.366 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.634 0.366 0.000
Z02 Examination and encounter for administrative purposes
0.634 0.366 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.634 0.366 0.000
Z60.9 Problem related to social environment, unspecified
0.633 0.367 0.000
Z60.8 Other problems related to social environment
0.633 0.367 0.000
Z60.5 Target of perceived adverse discrimination and persecution
0.633 0.367 0.000
Z60.4 Social exclusion and rejection
0.633 0.367 0.000
Z60.3 Acculturation difficulty
0.633 0.367 0.000
Z60.1 Atypical parenting situation
0.633 0.367 0.000
Z60.0 Problems of adjustment to life-cycle transitions
0.633 0.367 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.633 0.367 0.000
F30-F39 Mood [affective] disorders
0.633 0.367 0.000
G96 Other disorders of central nervous system
0.633 0.367 0.000
E20-E35 Disorders of other endocrine glands
0.632 0.368 0.000
M90 Osteopathies in diseases classified elsewhere
0.631 0.369 0.000
R25.3 Fasciculation
0.631 0.369 0.000
R25.0 Abnormal head movements
0.631 0.369 0.000
E85 Amyloidosis
0.630 0.370 0.000
E84 Cystic fibrosis
0.630 0.370 0.000
E79 Disorders of purine and pyrimidine metabolism
0.630 0.370 0.000
E77 Disorders of glycoprotein metabolism
0.630 0.370 0.000
E76 Disorders of glycosaminoglycan metabolism
0.630 0.370 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.630 0.370 0.000
E74 Other disorders of carbohydrate metabolism
0.630 0.370 0.000
E73 Lactose intolerance
0.630 0.370 0.000
E72 Other disorders of amino-acid metabolism
0.630 0.370 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.630 0.370 0.000
E70 Disorders of aromatic amino-acid metabolism
0.630 0.370 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.630 0.370 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.628 0.372 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.628 0.372 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.628 0.372 0.000
R06.7 Sneezing
0.627 0.372 0.000
R06.6 Hiccough
0.627 0.372 0.000
R06.3 Periodic breathing
0.627 0.372 0.000
R06.1 Stridor
0.627 0.372 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.626 0.374 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.626 0.374 0.000
S90-S99 Injuries to the ankle and foot
0.626 0.374 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.625 0.374 0.000
R06.2 Wheezing
0.625 0.375 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.625 0.375 0.000
Z96.1 Presence of intraocular lens
0.625 0.375 0.000
L91.9 Hypertrophic disorder of skin, unspecified
0.625 0.375 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.624 0.375 0.000
Z90.8 Acquired absence of other organs
0.624 0.376 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.624 0.376 0.000
H65-H75 Diseases of middle ear and mastoid
0.624 0.376 0.000
R01 Cardiac murmurs and other cardiac sounds
0.623 0.377 0.000
Z39 Postpartum care and examination
0.623 0.377 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.623 0.377 0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.622 0.378 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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