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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs114164869
log Bayes Factor = 6.47754
Chromosome 2   position 22,613,679  (GRCh37) Explore rs114164869 on Ensembl!
Variant rs114164869 is part of Cluster X0111

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
J30-J39 Other diseases of upper respiratory tract
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
J34 Other disorders of nose and nasal sinuses
0.999 0.001 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.994 0.006 0.000
J34.2 Deviated nasal septum
0.992 0.008 0.000
J34.3 Hypertrophy of nasal turbinates
0.987 0.013 0.000
E10-E14 Diabetes mellitus
0.987 0.013 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.987 0.013 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.985 0.015 0.000
E10 Insulin-dependent diabetes mellitus
0.985 0.015 0.000
I60-I69 Cerebrovascular diseases
0.980 0.020 0.000
F60-F69 Disorders of adult personality and behaviour
0.980 0.020 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.975 0.025 0.000
E10.3 With ophthalmic complications
0.969 0.031 0.000
F60 Specific personality disorders
0.966 0.034 0.000
S90-S99 Injuries to the ankle and foot
0.961 0.039 0.000
J95-J99 Other diseases of the respiratory system
0.953 0.047 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.951 0.049 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.950 0.050 0.000
J40-J47 Chronic lower respiratory diseases
0.949 0.051 0.000
J33 Nasal polyp
0.936 0.064 0.000
I20-I25 Ischaemic heart diseases
0.935 0.065 0.000
F30-F39 Mood [affective] disorders
0.935 0.065 0.000
F60.3 Emotionally unstable personality disorder
0.931 0.069 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.925 0.075 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.924 0.076 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.922 0.078 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.921 0.079 0.000
I77 Other disorders of arteries and arterioles
0.920 0.080 0.000
T93 Sequelae of injuries of lower limb
0.919 0.081 0.000
E10.4 With neurological complications
0.916 0.084 0.000
F17.1 Harmful use
0.914 0.086 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.906 0.094 0.000
I73 Other peripheral vascular diseases
0.904 0.096 0.000
J98 Other respiratory disorders
0.903 0.097 0.000
E14 Unspecified diabetes mellitus
0.900 0.100 0.000
S40-S49 Injuries to the shoulder and upper arm
0.898 0.102 0.000
I21 Acute myocardial infarction
0.894 0.106 0.000
T43.2 Other and unspecified antidepressants
0.891 0.109 0.000
J33.0 Polyp of nasal cavity
0.888 0.112 0.000
F60.9 Personality disorder, unspecified
0.887 0.113 0.000
J32 Chronic sinusitis
0.885 0.115 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.882 0.118 0.000
Chapter VIII Diseases of the ear and mastoid process
0.879 0.121 0.000
I65.2 Occlusion and stenosis of carotid artery
0.879 0.121 0.000
I73.9 Peripheral vascular disease, unspecified
0.879 0.121 0.000
E11 Non-insulin-dependent diabetes mellitus
0.875 0.125 0.000
F32 Depressive episode
0.875 0.125 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.873 0.126 0.000
I60 Subarachnoid haemorrhage
0.870 0.130 0.000
S10-S19 Injuries to the neck
0.869 0.131 0.000
I72 Other aneurysm
0.867 0.133 0.000
I21.9 Acute myocardial infarction, unspecified
0.862 0.138 0.000
E14.3 With ophthalmic complications
0.858 0.142 0.000
E10.2 With renal complications
0.855 0.145 0.000
T92 Sequelae of injuries of upper limb
0.855 0.145 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.853 0.147 0.000
I10-I15 Hypertensive diseases
0.852 0.148 0.000
J44 Other chronic obstructive pulmonary disease
0.850 0.150 0.000
F80-F89 Disorders of psychological development
0.841 0.159 0.000
I05-I09 Chronic rheumatic heart diseases
0.841 0.159 0.000
J32.9 Chronic sinusitis, unspecified
0.836 0.164 0.000
I12 Hypertensive renal disease
0.834 0.166 0.000
F32.9 Depressive episode, unspecified
0.828 0.172 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.827 0.173 0.000
T39.1 4-Aminophenol derivatives
0.825 0.175 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.823 0.177 0.000
S80-S89 Injuries to the knee and lower leg
0.822 0.178 0.000
I12.0 Hypertensive renal disease with renal failure
0.822 0.178 0.000
F29 Unspecified nonorganic psychosis
0.818 0.182 0.000
J38.3 Other diseases of vocal cords
0.817 0.183 0.000
F33 Recurrent depressive disorder
0.816 0.184 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.815 0.185 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.813 0.187 0.000
H60-H62 Diseases of external ear
0.812 0.188 0.000
I77.8 Other specified disorders of arteries and arterioles
0.808 0.192 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.807 0.193 0.000
H65-H75 Diseases of middle ear and mastoid
0.807 0.193 0.000
J45 Asthma
0.804 0.196 0.000
I24 Other acute ischaemic heart diseases
0.802 0.198 0.000
E10.5 With peripheral circulatory complications
0.797 0.203 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.797 0.203 0.000
E10.8 With unspecified complications
0.796 0.204 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.796 0.204 0.000
J98.4 Other disorders of lung
0.792 0.208 0.000
I78 Diseases of capillaries
0.792 0.208 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.790 0.210 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.788 0.212 0.000
J98.9 Respiratory disorder, unspecified
0.788 0.212 0.000
E10.6 With other specified complications
0.787 0.213 0.000
T90 Sequelae of injuries of head
0.787 0.213 0.000
J60-J70 Lung diseases due to external agents
0.786 0.214 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.786 0.214 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.783 0.217 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.782 0.218 0.000
I77.6 Arteritis, unspecified
0.782 0.218 0.000
J34.1 Cyst and mucocele of nose and nasal sinus
0.780 0.220 0.000
J33.9 Nasal polyp, unspecified
0.778 0.222 0.000
S90 Superficial injury of ankle and foot
0.777 0.223 0.000
J20-J22 Other acute lower respiratory infections
0.773 0.227 0.000
J90-J94 Other diseases of pleura
0.772 0.228 0.000
S89 Other and unspecified injuries of lower leg
0.771 0.229 0.000
J42 Unspecified chronic bronchitis
0.771 0.229 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.771 0.229 0.000
H72 Perforation of tympanic membrane
0.770 0.230 0.000
Q80-Q89 Other congenital malformations
0.769 0.231 0.000
I62 Other nontraumatic intracranial haemorrhage
0.768 0.232 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.766 0.234 0.000
J98.8 Other specified respiratory disorders
0.766 0.234 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.766 0.234 0.000
E11.9 Without complications
0.763 0.237 0.000
S99 Other and unspecified injuries of ankle and foot
0.761 0.239 0.000
I72.4 Aneurysm of artery of lower extremity
0.760 0.240 0.000
S40 Superficial injury of shoulder and upper arm
0.760 0.240 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.760 0.240 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.756 0.244 0.000
S92 Fracture of foot, except ankle
0.755 0.245 0.000
E10.0 With coma
0.753 0.247 0.000
J46 Status asthmaticus
0.750 0.250 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.750 0.250 0.000
T93.2 Sequelae of other fractures of lower limb
0.748 0.252 0.000
I70 Atherosclerosis
0.746 0.254 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.746 0.254 0.000
T00-T07 Injuries involving multiple body regions
0.745 0.255 0.000
I61 Intracerebral haemorrhage
0.745 0.255 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.743 0.257 0.000
T98 Sequelae of other and unspecified effects of external causes
0.740 0.260 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.739 0.261 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.738 0.262 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.736 0.264 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.736 0.264 0.000
F99-F99 Unspecified mental disorder
0.733 0.267 0.000
S10 Superficial injury of neck
0.730 0.269 0.000
J37 Chronic laryngitis and laryngotracheitis
0.730 0.270 0.000
S42 Fracture of shoulder and upper arm
0.730 0.270 0.000
J30 Vasomotor and allergic rhinitis
0.729 0.271 0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.728 0.272 0.000
T38.1 Thyroid hormones and substitutes
0.728 0.272 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.727 0.273 0.000
T92.1 Sequelae of fracture of arm
0.727 0.273 0.000
T39.0 Salicylates
0.725 0.275 0.000
E40-E46 Malnutrition
0.719 0.281 0.000
S19 Other and unspecified injuries of neck
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.717 0.283 0.000
F70-F79 Mental retardation
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
F11 Mental and behavioural disorders due to use of opioids
0.716 0.284 0.000
E14.4 With neurological complications
0.716 0.284 0.000
I00-I02 Acute rheumatic fever
0.716 0.284 0.000
S91 Open wound of ankle and foot
0.715 0.285 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.712 0.287 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.712 0.287 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.712 0.287 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.712 0.287 0.000
T36 Poisoning by systemic antibiotics
0.712 0.287 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.712 0.288 0.000
S86 Injury of muscle and tendon at lower leg level
0.712 0.288 0.000
Q50-Q56 Congenital malformations of genital organs
0.711 0.289 0.000
H60 Otitis externa
0.711 0.289 0.000
J00-J06 Acute upper respiratory infections
0.711 0.289 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.710 0.289 0.000
T93.0 Sequelae of open wound of lower limb
0.710 0.290 0.000
E12 Malnutrition-related diabetes mellitus
0.708 0.292 0.000
S89.9 Unspecified injury of lower leg
0.707 0.293 0.000
T51 Toxic effect of alcohol
0.707 0.293 0.000
E10.7 With multiple complications
0.706 0.294 0.000
J39 Other diseases of upper respiratory tract
0.706 0.294 0.000
J09-J18 Influenza and pneumonia
0.705 0.295 0.000
H61 Other disorders of external ear
0.704 0.296 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.703 0.297 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.703 0.297 0.000
F68 Other disorders of adult personality and behaviour
0.703 0.297 0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation
0.703 0.297 0.000
F65 Disorders of sexual preference
0.703 0.297 0.000
F64 Gender identity disorders
0.703 0.297 0.000
F63 Habit and impulse disorders
0.703 0.297 0.000
F62 Enduring personality changes, not attributable to brain damage and disease
0.703 0.297 0.000
F69 Unspecified disorder of adult personality and behaviour
0.703 0.297 0.000
F61 Mixed and other personality disorders
0.703 0.297 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.701 0.299 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.701 0.299 0.000
F32.1 Moderate depressive episode
0.701 0.299 0.000
T40.4 Other synthetic narcotics
0.700 0.300 0.000
T95 Sequelae of burns, corrosions and frostbite
0.699 0.301 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.699 0.301 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.699 0.301 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.699 0.301 0.000
F80 Specific developmental disorders of speech and language
0.699 0.301 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.698 0.302 0.000
Q60-Q64 Congenital malformations of the urinary system
0.697 0.303 0.000
S41 Open wound of shoulder and upper arm
0.697 0.303 0.000
I73.8 Other specified peripheral vascular diseases
0.696 0.304 0.000
S42.0 Fracture of clavicle
0.695 0.305 0.000
F02 Dementia in other diseases classified elsewhere
0.695 0.305 0.000
S70-S79 Injuries to the hip and thigh
0.694 0.306 0.000
F60.8 Other specific personality disorders
0.693 0.307 0.000
F60.7 Dependent personality disorder
0.693 0.307 0.000
F60.6 Anxious [avoidant] personality disorder
0.693 0.307 0.000
F60.5 Anankastic personality disorder
0.693 0.307 0.000
F60.4 Histrionic personality disorder
0.693 0.307 0.000
F60.2 Dissocial personality disorder
0.693 0.307 0.000
F60.1 Schizoid personality disorder
0.693 0.307 0.000
F60.0 Paranoid personality disorder
0.693 0.307 0.000
I08 Multiple valve diseases
0.691 0.309 0.000
I24.8 Other forms of acute ischaemic heart disease
0.691 0.309 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.691 0.309 0.000
I78.1 Naevus, nonneoplastic
0.691 0.309 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.690 0.310 0.000
S93.1 Dislocation of toe(s)
0.690 0.310 0.000
S98 Traumatic amputation of ankle and foot
0.689 0.311 0.000
S97 Crushing injury of ankle and foot
0.689 0.311 0.000
S95 Injury of blood vessels at ankle and foot level
0.689 0.311 0.000
S94 Injury of nerves at ankle and foot level
0.689 0.311 0.000
I60.4 Subarachnoid haemorrhage from basilar artery
0.689 0.311 0.000
I72.2 Aneurysm of renal artery
0.687 0.313 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.687 0.313 0.000
J47 Bronchiectasis
0.687 0.313 0.000
T93.1 Sequelae of fracture of femur
0.684 0.316 0.000
J96 Respiratory failure, not elsewhere classified
0.683 0.317 0.000
I22 Subsequent myocardial infarction
0.682 0.318 0.000
T43.9 Psychotropic drug, unspecified
0.682 0.318 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.682 0.318 0.000
T43.6 Psychostimulants with abuse potential
0.682 0.318 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.682 0.318 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.682 0.318 0.000
I05 Rheumatic mitral valve diseases
0.681 0.319 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.681 0.319 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.681 0.319 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.681 0.319 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.681 0.319 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.681 0.319 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.681 0.319 0.000
J98.5 Diseases of mediastinum, not elsewhere classified
0.681 0.319 0.000
J41 Simple and mucopurulent chronic bronchitis
0.681 0.319 0.000
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level
0.679 0.320 0.000
J94 Other pleural conditions
0.679 0.321 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.678 0.322 0.000
I72.8 Aneurysm of other specified arteries
0.677 0.323 0.000
T90.9 Sequelae of unspecified injury of head
0.675 0.325 0.000
I60.8 Other subarachnoid haemorrhage
0.674 0.326 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.674 0.326 0.000
J98.1 Pulmonary collapse
0.673 0.327 0.000
F00 Dementia in Alzheimer's disease
0.672 0.328 0.000
J33.1 Polypoid sinus degeneration
0.671 0.329 0.000
J32.2 Chronic ethmoidal sinusitis
0.671 0.329 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.671 0.329 0.000
S42.00 Fracture of clavicle (closed)
0.671 0.329 0.000
I23 Certain current complications following acute myocardial infarction
0.670 0.329 0.000
F38 Other mood [affective] disorders
0.670 0.330 0.000
F34 Persistent mood [affective] disorders
0.670 0.330 0.000
F39 Unspecified mood [affective] disorder
0.670 0.330 0.000
J45.0 Predominantly allergic asthma
0.670 0.330 0.000
E11.6 With other specified complications
0.669 0.331 0.000
Q00-Q07 Congenital malformations of the nervous system
0.669 0.331 0.000
T79-T79 Certain early complications of trauma
0.668 0.332 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.666 0.334 0.000
J43 Emphysema
0.666 0.334 0.000
E11.8 With unspecified complications
0.666 0.334 0.000
E13 Other specified diabetes mellitus
0.666 0.334 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.665 0.335 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.664 0.336 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.663 0.337 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.663 0.337 0.000
T39.4 Antirheumatics, not elsewhere classified
0.663 0.337 0.000
T39.2 Pyrazolone derivatives
0.663 0.337 0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb
0.663 0.337 0.000
S93.0 Dislocation of ankle joint
0.663 0.337 0.000
F17.9 Unspecified mental and behavioural disorder
0.663 0.337 0.000
F17.8 Other mental and behavioural disorders
0.663 0.337 0.000
F17.7 Residual and late-onset psychotic disorder
0.663 0.337 0.000
F17.6 Amnesic syndrome
0.663 0.337 0.000
F17.5 Psychotic disorder
0.663 0.337 0.000
F17.4 Withdrawal state with delirium
0.663 0.337 0.000
F17.3 Withdrawal state
0.663 0.337 0.000
F17.0 Acute intoxication
0.663 0.337 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.662 0.338 0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.661 0.339 0.000
I65.8 Occlusion and stenosis of other precerebral artery
0.661 0.339 0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.661 0.339 0.000
I65.1 Occlusion and stenosis of basilar artery
0.661 0.339 0.000
I65.0 Occlusion and stenosis of vertebral artery
0.661 0.339 0.000
J30.4 Allergic rhinitis, unspecified
0.660 0.340 0.000
I77.5 Necrosis of artery
0.659 0.341 0.000
I77.4 Coeliac artery compression syndrome
0.659 0.341 0.000
I77.3 Arterial fibromuscular dysplasia
0.659 0.341 0.000
I77.2 Rupture of artery
0.659 0.341 0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb
0.659 0.341 0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb
0.659 0.341 0.000
T93.4 Sequelae of injury of nerve of lower limb
0.659 0.341 0.000
I77.0 Arteriovenous fistula, acquired
0.658 0.342 0.000
F25 Schizoaffective disorders
0.658 0.342 0.000
H66 Suppurative and unspecified otitis media
0.654 0.346 0.000
I71 Aortic aneurysm and dissection
0.653 0.347 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.653 0.347 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.652 0.348 0.000
I69 Sequelae of cerebrovascular disease
0.652 0.348 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.652 0.348 0.000
E11.2 With renal complications
0.651 0.349 0.000
F81 Specific developmental disorders of scholastic skills
0.650 0.349 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.650 0.350 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.650 0.350 0.000
Q35-Q37 Cleft lip and cleft palate
0.650 0.350 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.650 0.350 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.648 0.352 0.000
E11.3 With ophthalmic complications
0.648 0.352 0.000
J98.6 Disorders of diaphragm
0.647 0.353 0.000
J98.3 Compensatory emphysema
0.647 0.353 0.000
J98.2 Interstitial emphysema
0.647 0.353 0.000
S12 Fracture of neck
0.646 0.354 0.000
E50-E64 Other nutritional deficiencies
0.646 0.354 0.000
E14.8 With unspecified complications
0.645 0.354 0.000
E14.7 With multiple complications
0.645 0.354 0.000
E14.6 With other specified complications
0.645 0.354 0.000
E14.5 With peripheral circulatory complications
0.645 0.354 0.000
E14.2 Withrenal complications
0.645 0.354 0.000
E14.1 With ketoacidosis
0.645 0.354 0.000
E14.0 With coma
0.645 0.354 0.000
S89.8 Other specified injuries of lower leg
0.644 0.355 0.000
J32.8 Other chronic sinusitis
0.644 0.356 0.000
S48 Traumatic amputation of shoulder and upper arm
0.644 0.356 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.644 0.356 0.000
S44 Injury of nerves at shoulder and upper arm level
0.644 0.356 0.000
S47 Crushing injury of shoulder and upper arm
0.644 0.356 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.641 0.359 0.000
S50-S59 Injuries to the elbow and forearm
0.640 0.360 0.000
F30 Manic episode
0.639 0.361 0.000
J00 Acute nasopharyngitis [common cold]
0.639 0.361 0.000
F23 Acute and transient psychotic disorders
0.639 0.361 0.000
I25 Chronic ischaemic heart disease
0.638 0.362 0.000
T92.9 Sequelae of unspecified injury of upper limb
0.638 0.362 0.000
T92.0 Sequelae of open wound of upper limb
0.637 0.363 0.000
S90.9 Superficial injury of ankle and foot, unspecified
0.637 0.363 0.000
J32.3 Chronic sphenoidal sinusitis
0.634 0.366 0.000
J32.1 Chronic frontal sinusitis
0.634 0.366 0.000
S86.8 Injury of other muscles and tendons at lower leg level
0.633 0.367 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.633 0.367 0.000
H69 Other disorders of Eustachian tube
0.633 0.367 0.000
S40.0 Contusion of shoulder and upper arm
0.633 0.367 0.000
F28 Other nonorganic psychotic disorders
0.633 0.367 0.000
F24 Induced delusional disorder
0.633 0.367 0.000
F21 Schizotypal disorder
0.633 0.367 0.000
T91 Sequelae of injuries of neck and trunk
0.632 0.368 0.000
I09 Other rheumatic heart diseases
0.632 0.368 0.000
S10.9 Superficial injury of neck, part unspecified
0.631 0.369 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.631 0.369 0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems
0.631 0.369 0.000
E11.5 With peripheral circulatory complications
0.631 0.369 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.631 0.369 0.000
T17 Foreign body in respiratory tract
0.631 0.369 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.631 0.369 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.630 0.370 0.000
I77.1 Stricture of artery
0.629 0.371 0.000
J91 Pleural effusion in conditions classified elsewhere
0.628 0.372 0.000
J92 Pleural plaque
0.628 0.372 0.000
E11.7 With multiple complications
0.627 0.373 0.000
F32.8 Other depressive episodes
0.627 0.373 0.000
J45.9 Asthma, unspecified
0.627 0.373 0.000
T38.9 Other and unspecified hormone antagonists
0.626 0.374 0.000
T38.8 Other and unspecified hormones and their synthetic substitutes
0.626 0.374 0.000
T38.7 Androgens and anabolic congeners
0.626 0.374 0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.626 0.374 0.000
T38.5 Other oestrogens and progestogens
0.626 0.374 0.000
T38.4 Oral contraceptives
0.626 0.374 0.000
T38.2 Antithyroid drugs
0.626 0.374 0.000
T38.0 Glucocorticoids and synthetic analogues
0.626 0.374 0.000
J38.5 Laryngeal spasm
0.626 0.374 0.000
E11.1 With ketoacidosis
0.624 0.376 0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.624 0.376 0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.624 0.376 0.000
I60.5 Subarachnoid haemorrhage from vertebral artery
0.624 0.376 0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.624 0.376 0.000
S17 Crushing injury of neck
0.623 0.377 0.000
S15 Injury of blood vessels at neck level
0.623 0.377 0.000
S14 Injury of nerves and spinal cord at neck level
0.623 0.377 0.000
S11 Open wound of neck
0.623 0.377 0.000
S18 Traumatic amputation at neck level
0.623 0.377 0.000
S16 Injury of muscle and tendon at neck level
0.623 0.377 0.000
Chapter XX External causes of morbidity and mortality
0.622 0.378 0.000
E11.0 With coma
0.622 0.378 0.000
I72.9 Aneurysm of unspecified site
0.621 0.378 0.000
I72.6 Aneurysm and dissection of vertebral artery
0.621 0.378 0.000
I72.5 Aneurysm and dissection of other precerebral arteries
0.621 0.378 0.000
I72.1 Aneurysm of artery of upper extremity
0.621 0.378 0.000
S92.1 Fracture of talus
0.621 0.379 0.000
F45 Somatoform disorders
0.618 0.382 0.000
J31.0 Chronic rhinitis
0.617 0.383 0.000
S99.9 Unspecified injury of ankle and foot
0.617 0.383 0.000
H73 Other disorders of tympanic membrane
0.617 0.383 0.000
I21.4 Acute subendocardial myocardial infarction
0.616 0.384 0.000
F22 Persistent delusional disorders
0.615 0.384 0.000
T92.8 Sequelae of other specified injuries of upper limb
0.615 0.385 0.000
F43 Reaction to severe stress, and adjustment disorders
0.614 0.386 0.000
J22 Unspecified acute lower respiratory infection
0.614 0.386 0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb
0.613 0.387 0.000
T92.4 Sequelae of injury of nerve of upper limb
0.613 0.387 0.000
H72.2 Other marginal perforations of tympanic membrane
0.612 0.388 0.000
E10.1 With ketoacidosis
0.612 0.388 0.000
J38.6 Stenosis of larynx
0.612 0.388 0.000
F41 Other anxiety disorders
0.611 0.389 0.000
I13 Hypertensive heart and renal disease
0.611 0.389 0.000
I72.0 Aneurysm of carotid artery
0.610 0.390 0.000
I08.0 Disorders of both mitral and aortic valves
0.610 0.390 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.610 0.390 0.000
T92.2 Sequelae of fracture at wrist and hand level
0.609 0.391 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.609 0.391 0.000
F32.0 Mild depressive episode
0.608 0.392 0.000
Q83 Congenital malformations of breast
0.607 0.393 0.000
T58 Toxic effect of carbon monoxide
0.605 0.395 0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.605 0.395 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.604 0.395 0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb
0.604 0.395 0.000
F84 Pervasive developmental disorders
0.603 0.397 0.000
F89 Unspecified disorder of psychological development
0.603 0.397 0.000
F88 Other disorders of psychological development
0.603 0.397 0.000
F83 Mixed specific developmental disorders
0.603 0.397 0.000
F82 Specific developmental disorder of motor function
0.603 0.397 0.000
I06 Rheumatic aortic valve diseases
0.603 0.397 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.602 0.398 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.601 0.398 0.000
F42 Obsessive-compulsive disorder
0.601 0.399 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.600 0.399 0.000
T46.1 Calcium-channel blockers
0.600 0.399 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.600 0.400 0.000
T23 Burn and corrosion of wrist and hand
0.600 0.400 0.000
T90.5 Sequelae of intracranial injury
0.599 0.401 0.000
I61.5 Intracerebral haemorrhage, intraventricular
0.599 0.401 0.000
T90.4 Sequelae of injury of eye and orbit
0.597 0.403 0.000
T51.0 Ethanol
0.597 0.403 0.000
F80.1 Expressive language disorder
0.597 0.403 0.000
J94.8 Other specified pleural conditions
0.597 0.403 0.000
Q85 Phakomatoses, not elsewhere classified
0.596 0.404 0.000
J34.0 Abscess, furuncle and carbuncle of nose
0.594 0.405 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.594 0.406 0.000
J40 Bronchitis, not specified as acute or chronic
0.594 0.406 0.000
F02.3 Dementia in Parkinson's disease
0.593 0.407 0.000
S93.4 Sprain and strain of ankle
0.593 0.407 0.000
S93.6 Sprain and strain of other and unspecified parts of foot
0.593 0.407 0.000
S93.5 Sprain and strain of toe(s)
0.593 0.407 0.000
S93.3 Dislocation of other and unspecified parts of foot
0.593 0.407 0.000
S93.2 Rupture of ligaments at ankle and foot level
0.593 0.407 0.000
I05.0 Mitral stenosis
0.592 0.407 0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified
0.592 0.408 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.592 0.408 0.000
T21 Burn and corrosion of trunk
0.591 0.409 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.591 0.409 0.000
T65 Toxic effect of other and unspecified substances
0.590 0.410 0.000
T62 Toxic effect of other noxious substances eaten as food
0.590 0.410 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.590 0.410 0.000
T60 Toxic effect of pesticides
0.590 0.410 0.000
T59 Toxic effect of other gases, fumes and vapours
0.590 0.410 0.000
T57 Toxic effect of other inorganic substances
0.590 0.410 0.000
T56 Toxic effect of metals
0.590 0.410 0.000
T54 Toxic effect of corrosive substances
0.590 0.410 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.590 0.410 0.000
T52 Toxic effect of organic solvents
0.590 0.410 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.590 0.410 0.000
T55 Toxic effect of soaps and detergents
0.590 0.410 0.000
J32.4 Chronic pansinusitis
0.590 0.410 0.000
S88 Traumatic amputation of lower leg
0.590 0.410 0.000
S87 Crushing injury of lower leg
0.590 0.410 0.000
S85 Injury of blood vessels at lower leg level
0.590 0.410 0.000
S84 Injury of nerves at lower leg level
0.590 0.410 0.000
J38.0 Paralysis of vocal cords and larynx
0.589 0.411 0.000
T14 Injury of unspecified body region
0.588 0.412 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.588 0.412 0.000
T66-T78 Other and unspecified effects of external causes
0.586 0.414 0.000
H60.1 Cellulitis of external ear
0.586 0.414 0.000
F33.8 Other recurrent depressive disorders
0.585 0.415 0.000
F33.4 Recurrent depressive disorder, currently in remission
0.585 0.415 0.000
F33.0 Recurrent depressive disorder, current episode mild
0.585 0.415 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.583 0.417 0.000
F09 Unspecified organic or symptomatic mental disorder
0.583 0.417 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.583 0.417 0.000
H62 Disorders of external ear in diseases classified elsewhere
0.582 0.417 0.000
Q51 Congenital malformations of uterus and cervix
0.580 0.419 0.000
S92.2 Fracture of other tarsal bone(s)
0.580 0.419 0.000
I15 Secondary hypertension
0.580 0.420 0.000
H72.8 Other perforations of tympanic membrane
0.579 0.421 0.000
F48 Other neurotic disorders
0.579 0.421 0.000
F44 Dissociative [conversion] disorders
0.579 0.421 0.000
E65-E68 Obesity and other hyperalimentation
0.578 0.421 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.578 0.422 0.000
H68 Eustachian salpingitis and obstruction
0.578 0.422 0.000
H67 Otitis media in diseases classified elsewhere
0.578 0.422 0.000
J38.2 Nodules of vocal cords
0.578 0.422 0.000
H70 Mastoiditis and related conditions
0.578 0.422 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.577 0.423 0.000
J45.8 Mixed asthma
0.576 0.424 0.000
J45.1 Nonallergic asthma
0.576 0.424 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.576 0.424 0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.575 0.424 0.000
I24.1 Dressler's syndrome
0.575 0.425 0.000
J99.8 Respiratory disorders in other diseases classified elsewhere
0.574 0.425 0.000
I61.8 Other intracerebral haemorrhage
0.574 0.426 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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