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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs114387109
log Bayes Factor = 6.81391
Chromosome 6   position 31,852,617  (GRCh37) Explore rs114387109 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.001 0.999
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.005 0.995
E03.9 Hypothyroidism, unspecified
0.000 0.023 0.977
E03 Other hypothyroidism
0.000 0.039 0.961
E00-E07 Disorders of thyroid gland
0.000 0.048 0.952
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.099 0.901
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.108 0.892
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.112 0.888
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.113 0.887
E10 Insulin-dependent diabetes mellitus
0.000 0.117 0.883
E10-E14 Diabetes mellitus
0.000 0.119 0.881
E10.9 Without complications
0.000 0.123 0.877
K90.0 Coeliac disease
0.846 0.154 0.000
L40.9 Psoriasis, unspecified
0.000 0.171 0.829
L40 Psoriasis
0.000 0.173 0.827
L40.5 Arthropathic psoriasis
0.000 0.178 0.822
E10.3 With ophthalmic complications
0.000 0.180 0.820
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.181 0.819
E04 Other non-toxic goitre
0.000 0.194 0.806
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.211 0.789
E06 Thyroiditis
0.000 0.213 0.787
E05.9 Thyrotoxicosis, unspecified
0.000 0.232 0.768
M06 Other rheumatoid arthritis
0.000 0.234 0.766
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.262 0.738
E04.2 Non-toxic multinodular goitre
0.000 0.263 0.737
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.268 0.731
E50-E64 Other nutritional deficiencies
0.000 0.274 0.726
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.716
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.716
E70-E90 Metabolic disorders
0.000 0.285 0.715
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.296 0.704
L40-L45 Papulosquamous disorders
0.000 0.301 0.699
E03.5 Myxoedema coma
0.000 0.311 0.689
E03.4 Atrophy of thyroid (acquired)
0.000 0.311 0.689
E03.3 Postinfectious hypothyroidism
0.000 0.311 0.689
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.311 0.689
E03.1 Congenital hypothyroidism without goitre
0.000 0.311 0.689
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.311 0.689
E40-E46 Malnutrition
0.000 0.311 0.689
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.312 0.688
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.317 0.683
E00 Congenital iodine-deficiency syndrome
0.000 0.317 0.683
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.317 0.683
E06.3 Autoimmune thyroiditis
0.000 0.319 0.681
E89.0 Postprocedural hypothyroidism
0.000 0.325 0.675
E10.4 With neurological complications
0.000 0.330 0.670
E13 Other specified diabetes mellitus
0.000 0.340 0.660
E10.1 With ketoacidosis
0.000 0.344 0.655
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.356 0.644
E05.8 Other thyrotoxicosis
0.000 0.364 0.636
E05.5 Thyroid crisis or storm
0.000 0.364 0.636
E05.4 Thyrotoxicosis factitia
0.000 0.364 0.636
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.364 0.636
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.364 0.636
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.364 0.636
E03.8 Other specified hypothyroidism
0.000 0.364 0.636
E10.8 With unspecified complications
0.000 0.367 0.633
E10.7 With multiple complications
0.000 0.367 0.633
E10.6 With other specified complications
0.000 0.367 0.633
E10.5 With peripheral circulatory complications
0.000 0.367 0.633
E10.2 With renal complications
0.000 0.367 0.633
E10.0 With coma
0.000 0.367 0.633
E12 Malnutrition-related diabetes mellitus
0.000 0.368 0.632
L00-L08 Infections of the skin and subcutaneous tissue
0.000 0.370 0.630
L40.0 Psoriasis vulgaris
0.000 0.371 0.629
M06.0 Seronegative rheumatoid arthritis
0.000 0.374 0.626
E86 Volume depletion
0.000 0.394 0.606
L08 Other local infections of skin and subcutaneous tissue
0.000 0.405 0.595
L20-L30 Dermatitis and eczema
0.000 0.406 0.594
E65-E68 Obesity and other hyperalimentation
0.000 0.406 0.594
L40.8 Other psoriasis
0.000 0.407 0.593
L40.4 Guttate psoriasis
0.000 0.407 0.593
L40.3 Pustulosis palmaris et plantaris
0.000 0.407 0.593
L40.2 Acrodermatitis continua
0.000 0.407 0.593
L40.1 Generalised pustular psoriasis
0.000 0.407 0.593
E53 Deficiency of other B group vitamins
0.000 0.414 0.586
E55 Vitamin D deficiency
0.000 0.418 0.582
L02 Cutaneous abscess, furuncle and carbuncle
0.000 0.419 0.581
E04.8 Other specified non-toxic goitre
0.000 0.422 0.578
E04.0 Non-toxic diffuse goitre
0.000 0.422 0.578
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.427 0.573
E88 Other metabolic disorders
0.000 0.433 0.567
E07 Other disorders of thyroid
0.000 0.434 0.566
E06.5 Other chronic thyroiditis
0.000 0.436 0.564
E06.4 Drug-induced thyroiditis
0.000 0.436 0.564
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.436 0.564
E06.1 Subacute thyroiditis
0.000 0.436 0.564
E06.0 Acute thyroiditis
0.000 0.436 0.564
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.000 0.441 0.559
L29 Pruritus
0.000 0.443 0.557
M06.8 Other specified rheumatoid arthritis
0.000 0.451 0.549
M06.4 Inflammatory polyarthropathy
0.000 0.451 0.549
M06.2 Rheumatoid bursitis
0.000 0.451 0.549
M06.1 Adult-onset Still's disease
0.000 0.451 0.549
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.455 0.545
E46 Unspecified protein-energy malnutrition
0.000 0.456 0.544
E06.9 Thyroiditis, unspecified
0.000 0.461 0.539
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.000 0.468 0.532
E04.1 Non-toxic single thyroid nodule
0.000 0.468 0.532
M05-M14 Inflammatory polyarthropathies
0.000 0.470 0.530
M06.3 Rheumatoid nodule
0.000 0.471 0.529
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.478 0.522
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.479 0.521
E63 Other nutritional deficiencies
0.000 0.479 0.521
E56 Other vitamin deficiencies
0.000 0.479 0.521
E51 Thiamine deficiency
0.000 0.479 0.521
E50 Vitamin A deficiency
0.000 0.479 0.521
E60 Dietary zinc deficiency
0.000 0.479 0.521
E59 Dietary selenium deficiency
0.000 0.479 0.521
E58 Dietary calcium deficiency
0.000 0.479 0.521
E54 Ascorbic acid deficiency
0.000 0.479 0.521
E52 Niacin deficiency [pellagra]
0.000 0.479 0.521
E04.9 Non-toxic goitre, unspecified
0.000 0.484 0.516
E84 Cystic fibrosis
0.000 0.488 0.512
E79 Disorders of purine and pyrimidine metabolism
0.000 0.488 0.512
E77 Disorders of glycoprotein metabolism
0.000 0.488 0.512
E76 Disorders of glycosaminoglycan metabolism
0.000 0.488 0.512
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.488 0.512
E73 Lactose intolerance
0.000 0.488 0.512
E72 Other disorders of amino-acid metabolism
0.000 0.488 0.512
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.488 0.512
E70 Disorders of aromatic amino-acid metabolism
0.000 0.488 0.512
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.488 0.512
L29.0 Pruritus ani
0.000 0.491 0.509
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.000 0.495 0.505
E89.2 Postprocedural hypoparathyroidism
0.000 0.496 0.504
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.497 0.503
L44 Other papulosquamous disorders
0.000 0.498 0.501
L41 Parapsoriasis
0.000 0.498 0.501
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.498 0.501
E13.9 Without complications
0.000 0.499 0.501
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.506 0.494
E45 Retarded development following protein-energy malnutrition
0.000 0.506 0.494
E43 Unspecified severe protein-energy malnutrition
0.000 0.506 0.494
E42 Marasmic kwashiorkor
0.000 0.506 0.494
E41 Nutritional marasmus
0.000 0.506 0.494
E40 Kwashiorkor
0.000 0.506 0.494
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.506 0.493
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.506 0.493
E89.5 Postprocedural testicular hypofunction
0.000 0.506 0.493
E89.4 Postprocedural ovarian failure
0.000 0.506 0.493
E89.1 Postprocedural hypoinsulinaemia
0.000 0.506 0.493
E89.3 Postprocedural hypopituitarism
0.000 0.507 0.493
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.510 0.489
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.510 0.489
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.510 0.489
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.510 0.489
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.510 0.489
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.510 0.489
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.510 0.489
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.510 0.489
E74 Other disorders of carbohydrate metabolism
0.000 0.512 0.488
E53.8 Deficiency of other specified B group vitamins
0.000 0.514 0.486
L27 Dermatitis due to substances taken internally
0.000 0.517 0.483
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.518 0.482
E61 Deficiency of other nutrient elements
0.000 0.521 0.479
E55.9 Vitamin D deficiency, unspecified
0.000 0.522 0.478
L05 Pilonidal cyst
0.000 0.523 0.477
L08.8 Other specified local infections of skin and subcutaneous tissue
0.000 0.525 0.475
M07 Psoriatic and enteropathic arthropathies
0.000 0.525 0.475
L43 Lichen planus
0.000 0.526 0.474
E13.8 With unspecified complications
0.000 0.527 0.473
E13.7 With multiple complications
0.000 0.527 0.473
E13.6 With other specified complications
0.000 0.527 0.473
E13.5 With peripheral circulatory complications
0.000 0.527 0.473
E13.4 With neurological complications
0.000 0.527 0.473
E13.3 With ophthalmic complications
0.000 0.527 0.473
E13.2 With renal complications
0.000 0.527 0.473
E13.1 With ketoacidosis
0.000 0.527 0.473
E13.0 With coma
0.000 0.527 0.473
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.532 0.468
M05 Seropositive rheumatoid arthritis
0.000 0.537 0.463
L10-L14 Bullous disorders
0.000 0.538 0.461
L29.2 Pruritus vulvae
0.000 0.539 0.461
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.539 0.461
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.541 0.459
E12.9 Without complications
0.000 0.547 0.453
E12.8 With unspecified complications
0.000 0.547 0.453
E12.7 With multiple complications
0.000 0.547 0.453
E12.6 With other specified complications
0.000 0.547 0.453
E12.5 With peripheral circulatory complications
0.000 0.547 0.453
E12.4 With neurological complications
0.000 0.547 0.453
E12.3 With ophthalmic complications
0.000 0.547 0.453
E12.2 With renal complications
0.000 0.547 0.453
E12.1 With ketoacidosis
0.000 0.547 0.453
E12.0 With coma
0.000 0.547 0.453
L04 Acute lymphadenitis
0.000 0.548 0.452
L01 Impetigo
0.000 0.548 0.452
L00 Staphylococcal scalded skin syndrome
0.000 0.548 0.452
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock
0.000 0.549 0.451
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.551 0.449
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.551 0.449
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.551 0.449
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.551 0.449
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.551 0.449
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.551 0.449
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.551 0.449
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.551 0.449
L28 Lichen simplex chronicus and prurigo
0.000 0.554 0.446
M07.3 Other psoriatic arthropathies
0.000 0.564 0.436
E85 Amyloidosis
0.000 0.565 0.434
L08.1 Erythrasma
0.000 0.573 0.426
L08.0 Pyoderma
0.000 0.573 0.426
L25 Unspecified contact dermatitis
0.000 0.574 0.426
L24 Irritant contact dermatitis
0.000 0.574 0.426
L23 Allergic contact dermatitis
0.000 0.574 0.426
L21 Seborrhoeic dermatitis
0.000 0.574 0.426
L26 Exfoliative dermatitis
0.000 0.574 0.426
L22 Diaper [napkin] dermatitis
0.000 0.574 0.426
E67 Other hyperalimentation
0.000 0.574 0.426
E68 Sequelae of hyperalimentation
0.000 0.574 0.426
E65 Localised adiposity
0.000 0.574 0.426
L57.0 Actinic keratosis
0.000 0.577 0.423
L03 Cellulitis
0.000 0.578 0.422
E53.9 Vitamin B deficiency, unspecified
0.000 0.579 0.420
E53.1 Pyridoxine deficiency
0.000 0.579 0.420
E53.0 Riboflavin deficiency
0.000 0.579 0.420
E55.0 Rickets, active
0.000 0.583 0.417
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites
0.000 0.583 0.417
L42 Pityriasis rosea
0.000 0.584 0.416
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.584 0.416
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.585 0.414
L29.9 Pruritus, unspecified
0.000 0.586 0.414
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.588 0.412
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.589 0.411
L58 Radiodermatitis
0.000 0.589 0.411
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.589 0.411
L55 Sunburn
0.000 0.589 0.411
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.591 0.408
L20 Atopic dermatitis
0.000 0.593 0.407
E88.9 Metabolic disorder, unspecified
0.000 0.593 0.406
E88.8 Other specified metabolic disorders
0.000 0.593 0.406
E88.3 Tumour lysis syndrome
0.000 0.593 0.406
E88.2 Lipomatosis, not elsewhere classified
0.000 0.593 0.406
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.593 0.406
E07.8 Other specified disorders of thyroid
0.000 0.594 0.406
E07.1 Dyshormogenetic goitre
0.000 0.594 0.406
E07.0 Hypersecretion of calcitonin
0.000 0.594 0.406
E14 Unspecified diabetes mellitus
0.000 0.596 0.404
L27.0 Generalised skin eruption due to drugs and medicaments
0.000 0.596 0.404
L29.8 Other pruritus
0.000 0.600 0.400
L29.3 Anogenital pruritus, unspecified
0.000 0.600 0.400
L29.1 Pruritus scroti
0.000 0.600 0.400
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.606 0.394
M06.18 Adult-onset Still's disease (Other)
0.000 0.606 0.394
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.606 0.394
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.606 0.394
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.606 0.394
M06.14 Adult-onset Still's disease (Hand)
0.000 0.606 0.394
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.606 0.394
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.606 0.394
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.606 0.394
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.606 0.394
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.606 0.394
M06.28 Rheumatoid bursitis (Other)
0.000 0.606 0.394
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.606 0.394
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.606 0.394
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.606 0.394
M06.24 Rheumatoid bursitis (Hand)
0.000 0.606 0.394
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.606 0.394
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.606 0.394
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.606 0.394
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.606 0.394
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.606 0.394
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.606 0.394
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.606 0.394
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.606 0.394
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.606 0.394
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.606 0.394
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.606 0.394
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.606 0.394
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.606 0.394
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.606 0.394
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.606 0.394
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.606 0.394
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.606 0.394
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.606 0.394
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.606 0.394
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.606 0.394
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.606 0.394
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.606 0.394
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.606 0.394
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.606 0.394
E15 Nondiabetic hypoglycaemic coma
0.000 0.609 0.391
L02.0 Cutaneous abscess, furuncle and carbuncle of face
0.000 0.612 0.388
L05.0 Pilonidal cyst with abscess
0.000 0.614 0.386
E20-E35 Disorders of other endocrine glands
0.000 0.616 0.383
M12 Other specific arthropathies
0.000 0.620 0.380
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.620 0.380
M08 Juvenile arthritis
0.000 0.620 0.380
E66 Obesity
0.000 0.620 0.380
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.621 0.379
M06.38 Rheumatoid nodule (Other)
0.000 0.621 0.379
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.621 0.379
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.621 0.379
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.621 0.379
M06.33 Rheumatoid nodule (Forearm)
0.000 0.621 0.379
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.621 0.379
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.621 0.379
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.621 0.379
M11 Other crystal arthropathies
0.000 0.621 0.379
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.626 0.374
L57.5 Actinic granuloma
0.000 0.626 0.374
L57.4 Cutis laxa senilis
0.000 0.626 0.374
L57.3 Poikiloderma of Civatte
0.000 0.626 0.374
L57.2 Cutis rhomboidalis nuchae
0.000 0.626 0.374
L57.1 Actinic reticuloid
0.000 0.626 0.374
E50.9 Vitamin A deficiency, unspecified
0.000 0.626 0.373
E50.8 Other manifestations of vitamin A deficiency
0.000 0.626 0.373
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.626 0.373
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.626 0.373
E50.5 Vitamin A deficiency with night blindness
0.000 0.626 0.373
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.626 0.373
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.626 0.373
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.626 0.373
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.626 0.373
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.626 0.373
E51.9 Thiamine deficiency, unspecified
0.000 0.626 0.373
E51.8 Other manifestations of thiamine deficiency
0.000 0.626 0.373
E51.2 Wernicke's encephalopathy
0.000 0.626 0.373
E51.1 Beriberi
0.000 0.626 0.373
E56.9 Vitamin deficiency, unspecified
0.000 0.626 0.373
E56.8 Deficiency of other vitamins
0.000 0.626 0.373
E56.1 Deficiency of vitamin K
0.000 0.626 0.373
E56.0 Deficiency of vitamin E
0.000 0.626 0.373
E63.9 Nutritional deficiency, unspecified
0.000 0.626 0.373
E63.8 Other specified nutritional deficiencies
0.000 0.626 0.373
E63.1 Imbalance of constituents of food intake
0.000 0.626 0.373
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.626 0.373
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.626 0.373
E64.8 Sequelae of other nutritional deficiencies
0.000 0.626 0.373
E64.3 Sequelae of rickets
0.000 0.626 0.373
E64.2 Sequelae of vitamin C deficiency
0.000 0.626 0.373
E64.1 Sequelae of vitamin A deficiency
0.000 0.626 0.373
E64.0 Sequelae of protein-energy malnutrition
0.000 0.626 0.373
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified
0.000 0.628 0.371
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.630 0.370
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.632 0.367
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.632 0.367
E70.3 Albinism
0.000 0.632 0.367
E70.2 Disorders of tyrosine metabolism
0.000 0.632 0.367
E70.1 Other hyperphenylalaninaemias
0.000 0.632 0.367
E70.0 Classical phenylketonuria
0.000 0.632 0.367
E71.3 Disorders of fatty-acid metabolism
0.000 0.632 0.367
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.632 0.367
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.632 0.367
E71.0 Maple-syrup-urine disease
0.000 0.632 0.367
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.632 0.367
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.632 0.367
E72.5 Disorders of glycine metabolism
0.000 0.632 0.367
E72.4 Disorders of ornithine metabolism
0.000 0.632 0.367
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.632 0.367
E72.2 Disorders of urea cycle metabolism
0.000 0.632 0.367
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.632 0.367
E72.0 Disorders of amino-acid transport
0.000 0.632 0.367
E73.9 Lactose intolerance, unspecified
0.000 0.632 0.367
E73.8 Other lactose intolerance
0.000 0.632 0.367
E73.1 Secondary lactase deficiency
0.000 0.632 0.367
E73.0 Congenital lactase deficiency
0.000 0.632 0.367
E75.6 Lipid storage disorder, unspecified
0.000 0.632 0.367
E75.5 Other lipid storage disorders
0.000 0.632 0.367
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.632 0.367
E75.3 Sphingolipidosis, unspecified
0.000 0.632 0.367
E75.2 Other sphingolipidosis
0.000 0.632 0.367
E75.1 Other gangliosidosis
0.000 0.632 0.367
E75.0 GM2 gangliosidosis
0.000 0.632 0.367
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.632 0.367
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.632 0.367
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.632 0.367
E76.2 Other mucopolysaccharidoses
0.000 0.632 0.367
E76.1 Mucopolysaccharidosis, type II
0.000 0.632 0.367
E76.0 Mucopolysaccharidosis, type I
0.000 0.632 0.367
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.632 0.367
E77.8 Other disorders of glycoprotein metabolism
0.000 0.632 0.367
E77.1 Defects in glycoprotein degradation
0.000 0.632 0.367
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.632 0.367
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.632 0.367
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.632 0.367
E79.1 Lesch-Nyhan syndrome
0.000 0.632 0.367
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.632 0.367
E84.9 Cystic fibrosis, unspecified
0.000 0.632 0.367
E84.8 Cystic fibrosis with other manifestations
0.000 0.632 0.367
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.632 0.367
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.632 0.367
L02.1 Cutaneous abscess, furuncle and carbuncle of neck
0.000 0.633 0.367
M10 Gout
0.000 0.633 0.367
M14 Arthropathies in other diseases classified elsewhere
0.000 0.635 0.365
L41.9 Parapsoriasis, unspecified
0.000 0.640 0.360
L41.8 Other parapsoriasis
0.000 0.640 0.360
L41.5 Retiform parapsoriasis
0.000 0.640 0.360
L41.4 Large plaque parapsoriasis
0.000 0.640 0.360
L41.3 Small plaque parapsoriasis
0.000 0.640 0.360
L41.2 Lymphomatoid papulosis
0.000 0.640 0.360
L41.1 Pityriasis lichenoides chronica
0.000 0.640 0.360
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.640 0.360
L44.9 Papulosquamous disorder, unspecified
0.000 0.640 0.360
L44.8 Other specified papulosquamous disorders
0.000 0.640 0.360
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.640 0.360
L44.3 Lichen ruber moniliformis
0.000 0.640 0.360
L44.2 Lichen striatus
0.000 0.640 0.360
L44.1 Lichen nitidus
0.000 0.640 0.360
L44.0 Pityriasis rubra pilaris
0.000 0.640 0.360
M06.34 Rheumatoid nodule (Hand)
0.000 0.641 0.358
E44.1 Mild protein-energy malnutrition
0.000 0.645 0.354
E44.0 Moderate protein-energy malnutrition
0.000 0.645 0.354
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.650 0.350
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.650 0.350
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.650 0.350
E74.2 Disorders of galactose metabolism
0.000 0.650 0.350
E74.1 Disorders of fructose metabolism
0.000 0.650 0.350
E74.0 Glycogen storage disease
0.000 0.650 0.350
L30 Other dermatitis
0.000 0.653 0.347
L27.9 Dermatitis due to unspecified substance taken internally
0.000 0.653 0.346
L27.8 Dermatitis due to other substances taken internally
0.000 0.653 0.346
L27.2 Dermatitis due to ingested food
0.000 0.653 0.346
L27.1 Localised skin eruption due to drugs and medicaments
0.000 0.653 0.346
L50-L54 Urticaria and erythema
0.000 0.654 0.346
E61.9 Deficiency of nutrient element, unspecified
0.000 0.657 0.343
E61.8 Deficiency of other specified nutrient elements
0.000 0.657 0.343
E61.7 Deficiency of multiple nutrient elements
0.000 0.657 0.343
E61.6 Vanadium deficiency
0.000 0.657 0.343
E61.5 Molybdenum deficiency
0.000 0.657 0.343
E61.4 Chromium deficiency
0.000 0.657 0.343
E61.3 Manganese deficiency
0.000 0.657 0.343
E61.2 Magnesium deficiency
0.000 0.657 0.343
E61.0 Copper deficiency
0.000 0.657 0.343
M07.6 Other enteropathic arthropathies
0.000 0.659 0.341
M07.5 Arthropathy in ulcerative colitis
0.000 0.659 0.341
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.659 0.341
M07.2 Psoriatic spondylitis
0.000 0.659 0.341
M07.1 Arthritis mutilans
0.000 0.659 0.341
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.659 0.341
L43.8 Other lichen planus
0.000 0.660 0.340
L43.3 Subacute (active) lichen planus
0.000 0.660 0.340
L43.2 Lichenoid drug reaction
0.000 0.660 0.340
L43.1 Bullous lichen planus
0.000 0.660 0.340
L43.0 Hypertrophic lichen planus
0.000 0.660 0.340
L28.0 Lichen simplex chronicus
0.000 0.660 0.339
E87.7 Fluid overload
0.000 0.665 0.335
E66.8 Other obesity
0.000 0.665 0.335
M05.8 Other seropositive rheumatoid arthritis
0.000 0.668 0.332
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.668 0.332
M05.2 Rheumatoid vasculitis
0.000 0.668 0.332
M05.1 Rheumatoid lung disease
0.000 0.668 0.332
M05.0 Felty's syndrome
0.000 0.668 0.332
E87.2 Acidosis
0.000 0.669 0.331
L13 Other bullous disorders
0.000 0.669 0.331
L12 Pemphigoid
0.000 0.669 0.331
L11 Other acantholytic disorders
0.000 0.669 0.331
L10 Pemphigus
0.000 0.669 0.331
L14 Bullous disorders in diseases classified elsewhere
0.000 0.669 0.331
K90 Intestinal malabsorption
0.329 0.671 0.000
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.671 0.329
E80.6 Other disorders of bilirubin metabolism
0.000 0.671 0.329
E80.5 Crigler-Najjar syndrome
0.000 0.671 0.329
E80.3 Defects of catalase and peroxydase
0.000 0.671 0.329
E80.2 Other porphyria
0.000 0.671 0.329
E80.1 Porphyria cutanea tarda
0.000 0.671 0.329
E80.0 Hereditary erythropoietic porphyria
0.000 0.671 0.329
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.672 0.328
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.675 0.325
L01.1 Impetiginisation of other dermatoses
0.000 0.676 0.324
L01.0 Impetigo [any organism] [any site]
0.000 0.676 0.324
L04.9 Acute lymphadenitis, unspecified
0.000 0.676 0.324
L04.8 Acute lymphadenitis of other sites
0.000 0.676 0.324
L04.3 Acute lymphadenitis of lower limb
0.000 0.676 0.324
L04.2 Acute lymphadenitis of upper limb
0.000 0.676 0.324
L04.1 Acute lymphadenitis of trunk
0.000 0.676 0.324
L04.0 Acute lymphadenitis of face, head and neck
0.000 0.676 0.324
L03.1 Cellulitis of other parts of limb
0.000 0.680 0.320
L28.2 Other prurigo
0.000 0.680 0.320
L28.1 Prurigo nodularis
0.000 0.680 0.320
E27 Other disorders of adrenal gland
0.000 0.681 0.318
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.682 0.318
L03.2 Cellulitis of face
0.000 0.683 0.317
L05.9 Pilonidal cyst without abscess
0.000 0.685 0.315
M07.38 Other psoriatic arthropathies (Other)
0.000 0.687 0.313
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.687 0.313
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.687 0.313
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.687 0.313
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.687 0.313
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.687 0.313
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.687 0.313
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.687 0.313
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.687 0.313
L43.9 Lichen planus, unspecified
0.000 0.688 0.312
E85.8 Other amyloidosis
0.000 0.688 0.312
E85.3 Secondary systemic amyloidosis
0.000 0.688 0.312
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.688 0.312
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.688 0.312
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.688 0.312
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.000 0.690 0.310
L21.9 Seborrhoeic dermatitis, unspecified
0.000 0.694 0.306
L21.8 Other seborrhoeic dermatitis
0.000 0.694 0.306
L21.1 Seborrhoeic infantile dermatitis
0.000 0.694 0.306
L21.0 Seborrhoea capitis
0.000 0.694 0.306
L23.9 Allergic contact dermatitis, unspecified cause
0.000 0.694 0.306
L23.8 Allergic contact dermatitis due to other agents
0.000 0.694 0.306
L23.7 Allergic contact dermatitis due to plants, except food
0.000 0.694 0.306

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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