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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs114800680
log Bayes Factor = 14.5931
Chromosome 4   position 105,469,120  (GRCh37) Explore rs114800680 on Ensembl!
Variant rs114800680 is part of Cluster X0123

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
1.000 0.000 0.000
E70-E90 Metabolic disorders
0.999 0.001 0.000
I44 Atrioventricular and left bundle-branch block
0.998 0.002 0.000
Chapter X Diseases of the respiratory system
0.994 0.006 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.986 0.014 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.986 0.014 0.000
S00-S09 Injuries to the head
0.986 0.014 0.000
I60-I69 Cerebrovascular diseases
0.978 0.022 0.000
Chapter V Mental and behavioural disorders
0.976 0.024 0.000
E00-E07 Disorders of thyroid gland
0.974 0.026 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.969 0.031 0.000
I20-I25 Ischaemic heart diseases
0.965 0.035 0.000
F30-F39 Mood [affective] disorders
0.962 0.038 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.954 0.046 0.000
I44.7 Left bundle-branch block, unspecified
0.953 0.047 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.952 0.048 0.000
J20-J22 Other acute lower respiratory infections
0.952 0.048 0.000
I44.0 Atrioventricular block, first degree
0.947 0.053 0.000
I69 Sequelae of cerebrovascular disease
0.944 0.056 0.000
S09 Other and unspecified injuries of head
0.941 0.059 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.936 0.064 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.934 0.066 0.000
E78.0 Pure hypercholesterolaemia
0.932 0.068 0.000
T43.2 Other and unspecified antidepressants
0.928 0.072 0.000
Chapter I Certain infectious and parasitic diseases
0.924 0.076 0.000
J22 Unspecified acute lower respiratory infection
0.923 0.077 0.000
I25 Chronic ischaemic heart disease
0.922 0.078 0.000
E03 Other hypothyroidism
0.914 0.086 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.911 0.089 0.000
I44.1 Atrioventricular block, second degree
0.906 0.094 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.905 0.095 0.000
I50 Heart failure
0.904 0.096 0.000
J30-J39 Other diseases of upper respiratory tract
0.902 0.098 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.901 0.099 0.000
J33 Nasal polyp
0.897 0.103 0.000
M05-M14 Inflammatory polyarthropathies
0.897 0.103 0.000
F32 Depressive episode
0.896 0.104 0.000
S09.9 Unspecified injury of head
0.896 0.104 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.892 0.108 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.890 0.110 0.000
T42.4 Benzodiazepines
0.890 0.110 0.000
I44.2 Atrioventricular block, complete
0.889 0.111 0.000
E87.6 Hypokalaemia
0.889 0.111 0.000
E87.5 Hyperkalaemia
0.888 0.112 0.000
I42 Cardiomyopathy
0.888 0.112 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.887 0.113 0.000
B95-B98 Bacterial, viral and other infectious agents
0.886 0.114 0.000
S02 Fracture of skull and facial bones
0.885 0.115 0.000
I60 Subarachnoid haemorrhage
0.884 0.116 0.000
F33 Recurrent depressive disorder
0.882 0.118 0.000
I46 Cardiac arrest
0.879 0.121 0.000
S60-S69 Injuries to the wrist and hand
0.879 0.121 0.000
T51 Toxic effect of alcohol
0.876 0.124 0.000
I25.2 Old myocardial infarction
0.876 0.124 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.874 0.126 0.000
J33.9 Nasal polyp, unspecified
0.873 0.127 0.000
I05-I09 Chronic rheumatic heart diseases
0.873 0.127 0.000
E03.9 Hypothyroidism, unspecified
0.871 0.129 0.000
I50.0 Congestive heart failure
0.870 0.130 0.000
E88 Other metabolic disorders
0.866 0.134 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.863 0.137 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.860 0.140 0.000
Chapter VIII Diseases of the ear and mastoid process
0.859 0.141 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.859 0.141 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.852 0.148 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.851 0.149 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.850 0.150 0.000
M10 Gout
0.845 0.155 0.000
Chapter XX External causes of morbidity and mortality
0.845 0.155 0.000
J95-J99 Other diseases of the respiratory system
0.844 0.155 0.000
I72 Other aneurysm
0.843 0.157 0.000
R20 Disturbances of skin sensation
0.843 0.157 0.000
J90-J94 Other diseases of pleura
0.840 0.160 0.000
S80-S89 Injuries to the knee and lower leg
0.840 0.160 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.840 0.160 0.000
Chapter XXII Codes for special purposes
0.836 0.164 0.000
J33.0 Polyp of nasal cavity
0.834 0.166 0.000
R26 Abnormalities of gait and mobility
0.828 0.172 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.822 0.178 0.000
M13 Other arthritis
0.822 0.178 0.000
E87.2 Acidosis
0.821 0.179 0.000
T51.9 Alcohol, unspecified
0.821 0.179 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.819 0.181 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.817 0.183 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.816 0.184 0.000
F31 Bipolar affective disorder
0.814 0.185 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.814 0.186 0.000
R33 Retention of urine
0.814 0.186 0.000
R30-R39 Symptoms and signs involving the urinary system
0.813 0.187 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.812 0.188 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.812 0.188 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.811 0.189 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.811 0.189 0.000
M10.9 Gout, unspecified
0.809 0.191 0.000
E05.9 Thyrotoxicosis, unspecified
0.808 0.192 0.000
I20 Angina pectoris
0.806 0.194 0.000
M06 Other rheumatoid arthritis
0.806 0.194 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.804 0.196 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.799 0.201 0.000
S06 Intracranial injury
0.799 0.201 0.000
T66-T78 Other and unspecified effects of external causes
0.797 0.203 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.797 0.203 0.000
J60-J70 Lung diseases due to external agents
0.795 0.205 0.000
L20-L30 Dermatitis and eczema
0.795 0.205 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.794 0.206 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.794 0.206 0.000
E85 Amyloidosis
0.791 0.209 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.790 0.210 0.000
I46.0 Cardiac arrest with successful resuscitation
0.785 0.215 0.000
I07 Rheumatic tricuspid valve diseases
0.784 0.216 0.000
S00 Superficial injury of head
0.784 0.216 0.000
E86 Volume depletion
0.783 0.217 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.783 0.217 0.000
I30 Acute pericarditis
0.782 0.218 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.782 0.218 0.000
I35 Nonrheumatic aortic valve disorders
0.780 0.220 0.000
R20.2 Paraesthesia of skin
0.780 0.220 0.000
L60-L75 Disorders of skin appendages
0.780 0.220 0.000
I72.3 Aneurysm of iliac artery
0.779 0.221 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.777 0.223 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.777 0.223 0.000
E78.8 Other disorders of lipoprotein metabolism
0.774 0.226 0.000
I25.4 Coronary artery aneurysm
0.772 0.228 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.771 0.229 0.000
M10.99 Gout, unspecified (Site unspecified)
0.770 0.230 0.000
R05 Cough
0.769 0.231 0.000
E89.0 Postprocedural hypothyroidism
0.766 0.234 0.000
B99-B99 Other infectious diseases
0.764 0.236 0.000
F33.9 Recurrent depressive disorder, unspecified
0.764 0.236 0.000
S10-S19 Injuries to the neck
0.764 0.236 0.000
E73 Lactose intolerance
0.763 0.237 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.762 0.238 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.757 0.242 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.756 0.244 0.000
S09.8 Other specified injuries of head
0.754 0.246 0.000
M13.9 Arthritis, unspecified
0.751 0.249 0.000
T39.1 4-Aminophenol derivatives
0.750 0.250 0.000
J92 Pleural plaque
0.749 0.251 0.000
W20-W49 Exposure to inanimate mechanical forces
0.746 0.254 0.000
S61 Open wound of wrist and hand
0.746 0.254 0.000
R03.1 Nonspecific low blood-pressure reading
0.745 0.255 0.000
I36 Nonrheumatic tricuspid valve disorders
0.745 0.255 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.744 0.256 0.000
R00 Abnormalities of heart beat
0.742 0.258 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.741 0.259 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.741 0.259 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.741 0.259 0.000
S20-S29 Injuries to the thorax
0.740 0.260 0.000
J09-J18 Influenza and pneumonia
0.739 0.261 0.000
I67 Other cerebrovascular diseases
0.738 0.262 0.000
R21 Rash and other nonspecific skin eruption
0.738 0.262 0.000
R79 Other abnormal findings of blood chemistry
0.738 0.262 0.000
E78.5 Hyperlipidaemia, unspecified
0.738 0.262 0.000
E06 Thyroiditis
0.737 0.263 0.000
M80-M85 Disorders of bone density and structure
0.736 0.264 0.000
J33.8 Other polyp of sinus
0.736 0.264 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.735 0.265 0.000
S80 Superficial injury of lower leg
0.733 0.267 0.000
T63 Toxic effect of contact with venomous animals
0.732 0.268 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.732 0.268 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.731 0.269 0.000
I22 Subsequent myocardial infarction
0.731 0.269 0.000
I70 Atherosclerosis
0.730 0.270 0.000
I42.0 Dilated cardiomyopathy
0.725 0.275 0.000
T79-T79 Certain early complications of trauma
0.725 0.275 0.000
I27 Other pulmonary heart diseases
0.724 0.276 0.000
R23 Other skin changes
0.723 0.277 0.000
L30 Other dermatitis
0.722 0.278 0.000
B35-B49 Mycoses
0.720 0.280 0.000
I07.1 Tricuspid insufficiency
0.720 0.280 0.000
E04 Other non-toxic goitre
0.719 0.281 0.000
I42.9 Cardiomyopathy, unspecified
0.719 0.281 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.719 0.281 0.000
I47 Paroxysmal tachycardia
0.719 0.281 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.718 0.282 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.718 0.282 0.000
F32.1 Moderate depressive episode
0.718 0.282 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E40-E46 Malnutrition
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.717 0.283 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.717 0.283 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.717 0.283 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.717 0.283 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.717 0.283 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.717 0.283 0.000
T36 Poisoning by systemic antibiotics
0.717 0.283 0.000
E84 Cystic fibrosis
0.717 0.283 0.000
E79 Disorders of purine and pyrimidine metabolism
0.717 0.283 0.000
E77 Disorders of glycoprotein metabolism
0.717 0.283 0.000
E76 Disorders of glycosaminoglycan metabolism
0.717 0.283 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.717 0.283 0.000
E74 Other disorders of carbohydrate metabolism
0.717 0.283 0.000
E72 Other disorders of amino-acid metabolism
0.717 0.283 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.717 0.283 0.000
E70 Disorders of aromatic amino-acid metabolism
0.717 0.283 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.717 0.283 0.000
I44.6 Other and unspecified fascicular block
0.716 0.284 0.000
I44.5 Left posterior fascicular block
0.716 0.284 0.000
I44.4 Left anterior fascicular block
0.716 0.284 0.000
I44.3 Other and unspecified atrioventricular block
0.716 0.284 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.714 0.286 0.000
S70-S79 Injuries to the hip and thigh
0.714 0.286 0.000
I61 Intracerebral haemorrhage
0.713 0.287 0.000
M06.9 Rheumatoid arthritis, unspecified
0.713 0.287 0.000
S02.2 Fracture of nasal bones
0.712 0.288 0.000
I77 Other disorders of arteries and arterioles
0.711 0.289 0.000
I62 Other nontraumatic intracranial haemorrhage
0.710 0.290 0.000
I45 Other conduction disorders
0.709 0.291 0.000
S02.6 Fracture of mandible
0.708 0.292 0.000
I71 Aortic aneurysm and dissection
0.708 0.292 0.000
S90-S99 Injuries to the ankle and foot
0.708 0.292 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.708 0.292 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.707 0.292 0.000
F99-F99 Unspecified mental disorder
0.707 0.293 0.000
T43.9 Psychotropic drug, unspecified
0.707 0.293 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.707 0.293 0.000
T43.6 Psychostimulants with abuse potential
0.707 0.293 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.707 0.293 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.707 0.293 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.707 0.293 0.000
E87.4 Mixed disorder of acid-base balance
0.707 0.293 0.000
E87.3 Alkalosis
0.707 0.293 0.000
B65-B83 Helminthiases
0.707 0.293 0.000
S08 Traumatic amputation of part of head
0.707 0.293 0.000
S07 Crushing injury of head
0.707 0.293 0.000
S05 Injury of eye and orbit
0.707 0.293 0.000
S04 Injury of cranial nerves
0.707 0.293 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.707 0.293 0.000
M86-M90 Other osteopathies
0.705 0.295 0.000
M13.94 Arthritis, unspecified (Hand)
0.705 0.295 0.000
F60-F69 Disorders of adult personality and behaviour
0.705 0.295 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.704 0.296 0.000
H65-H75 Diseases of middle ear and mastoid
0.702 0.298 0.000
I25.5 Ischaemic cardiomyopathy
0.702 0.298 0.000
S02.1 Fracture of base of skull
0.701 0.299 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.701 0.299 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.701 0.299 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.700 0.300 0.000
F80-F89 Disorders of psychological development
0.700 0.300 0.000
F70-F79 Mental retardation
0.700 0.300 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.699 0.301 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.699 0.301 0.000
I34 Nonrheumatic mitral valve disorders
0.698 0.302 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.698 0.302 0.000
E00 Congenital iodine-deficiency syndrome
0.698 0.302 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.698 0.302 0.000
H80-H83 Diseases of inner ear
0.698 0.302 0.000
A80-A89 Viral infections of the central nervous system
0.696 0.304 0.000
S89 Other and unspecified injuries of lower leg
0.696 0.304 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.696 0.304 0.000
I78 Diseases of capillaries
0.695 0.305 0.000
E78.6 Lipoprotein deficiency
0.694 0.305 0.000
E78.4 Other hyperlipidaemia
0.694 0.305 0.000
E78.3 Hyperchylomicronaemia
0.694 0.305 0.000
E78.1 Pure hyperglyceridaemia
0.694 0.305 0.000
I69.3 Sequelae of cerebral infarction
0.694 0.306 0.000
J36 Peritonsillar abscess
0.694 0.306 0.000
M00-M03 Infectious arthropathies
0.693 0.307 0.000
I23 Certain current complications following acute myocardial infarction
0.692 0.308 0.000
B97.8 Other viral agents as the cause of diseases classified to other chapters
0.691 0.309 0.000
I50.9 Heart failure, unspecified
0.690 0.310 0.000
F31.9 Bipolar affective disorder, unspecified
0.690 0.310 0.000
F38 Other mood [affective] disorders
0.690 0.310 0.000
F34 Persistent mood [affective] disorders
0.690 0.310 0.000
F30 Manic episode
0.690 0.310 0.000
F39 Unspecified mood [affective] disorder
0.690 0.310 0.000
I31 Other diseases of pericardium
0.688 0.312 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.688 0.312 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.688 0.312 0.000
Q50-Q56 Congenital malformations of genital organs
0.687 0.313 0.000
L57.0 Actinic keratosis
0.686 0.314 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.686 0.314 0.000
M65-M68 Disorders of synovium and tendon
0.686 0.314 0.000
T51.0 Ethanol
0.685 0.315 0.000
S60 Superficial injury of wrist and hand
0.684 0.315 0.000
F32.0 Mild depressive episode
0.684 0.316 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.684 0.316 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.684 0.316 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.684 0.316 0.000
T42.3 Barbiturates
0.684 0.316 0.000
T42.2 Succinimides and oxazolidinediones
0.684 0.316 0.000
T42.1 Iminostilbenes
0.684 0.316 0.000
T42.0 Hydantoin derivatives
0.684 0.316 0.000
I10-I15 Hypertensive diseases
0.684 0.316 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.683 0.316 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.683 0.317 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.683 0.317 0.000
J21 Acute bronchiolitis
0.683 0.317 0.000
J20 Acute bronchitis
0.683 0.317 0.000
I49 Other cardiac arrhythmias
0.683 0.317 0.000
S06.5 Traumatic subdural haemorrhage
0.682 0.318 0.000
I24 Other acute ischaemic heart diseases
0.682 0.318 0.000
R00.1 Bradycardia, unspecified
0.681 0.319 0.000
S67 Crushing injury of wrist and hand
0.680 0.320 0.000
L29 Pruritus
0.680 0.320 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.679 0.321 0.000
F32.9 Depressive episode, unspecified
0.678 0.322 0.000
E78.2 Mixed hyperlipidaemia
0.677 0.323 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.677 0.323 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.677 0.323 0.000
I20.1 Angina pectoris with documented spasm
0.676 0.324 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.676 0.324 0.000
T90 Sequelae of injuries of head
0.675 0.324 0.000
J81 Pulmonary oedema
0.675 0.325 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.675 0.325 0.000
S09.7 Multiple injuries of head
0.675 0.325 0.000
S09.2 Traumatic rupture of ear drum
0.675 0.325 0.000
S09.1 Injury of muscle and tendon of head
0.675 0.325 0.000
S09.0 Injury of blood vessels of head, not elsewhere classified
0.675 0.325 0.000
T65 Toxic effect of other and unspecified substances
0.671 0.329 0.000
T62 Toxic effect of other noxious substances eaten as food
0.671 0.329 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.671 0.329 0.000
T60 Toxic effect of pesticides
0.671 0.329 0.000
T59 Toxic effect of other gases, fumes and vapours
0.671 0.329 0.000
T57 Toxic effect of other inorganic substances
0.671 0.329 0.000
T56 Toxic effect of metals
0.671 0.329 0.000
T54 Toxic effect of corrosive substances
0.671 0.329 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.671 0.329 0.000
T52 Toxic effect of organic solvents
0.671 0.329 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.671 0.329 0.000
T58 Toxic effect of carbon monoxide
0.671 0.329 0.000
T55 Toxic effect of soaps and detergents
0.671 0.329 0.000
S00.8 Superficial injury of other parts of head
0.670 0.330 0.000
L30.9 Dermatitis, unspecified
0.670 0.330 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.669 0.331 0.000
Q00-Q07 Congenital malformations of the nervous system
0.668 0.332 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.668 0.332 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.668 0.332 0.000
I21 Acute myocardial infarction
0.667 0.333 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.666 0.334 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.665 0.334 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.665 0.335 0.000
F43 Reaction to severe stress, and adjustment disorders
0.665 0.335 0.000
I20.9 Angina pectoris, unspecified
0.665 0.335 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.664 0.336 0.000
J90 Pleural effusion, not elsewhere classified
0.664 0.336 0.000
S02.8 Fractures of other skull and facial bones
0.663 0.337 0.000
V40-V49 Car occupant injured in transport accident
0.663 0.337 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.663 0.337 0.000
B50-B64 Protozoal diseases
0.663 0.337 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.663 0.337 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.663 0.337 0.000
A75-A79 Rickettsioses
0.663 0.337 0.000
A70-A74 Other diseases caused by chlamydiae
0.663 0.337 0.000
A65-A69 Other spirochaetal diseases
0.663 0.337 0.000
A20-A28 Certain zoonotic bacterial diseases
0.663 0.337 0.000
A15-A19 Tuberculosis
0.663 0.337 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.662 0.338 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.662 0.338 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.662 0.338 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.662 0.338 0.000
I74 Arterial embolism and thrombosis
0.661 0.339 0.000
I25.6 Silent myocardial ischaemia
0.661 0.339 0.000
I25.3 Aneurysm of heart
0.661 0.339 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.661 0.339 0.000
M10.96 Gout, unspecified (Lower leg)
0.660 0.340 0.000
Chapter VI Diseases of the nervous system
0.660 0.340 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.659 0.340 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.659 0.341 0.000
R20.8 Other and unspecified disturbances of skin sensation
0.658 0.341 0.000
J99.8 Respiratory disorders in other diseases classified elsewhere
0.657 0.343 0.000
B25-B34 Other viral diseases
0.656 0.344 0.000
S81 Open wound of lower leg
0.655 0.345 0.000
E03.8 Other specified hypothyroidism
0.655 0.345 0.000
E03.5 Myxoedema coma
0.655 0.345 0.000
E03.4 Atrophy of thyroid (acquired)
0.655 0.345 0.000
E03.3 Postinfectious hypothyroidism
0.655 0.345 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.655 0.345 0.000
E03.1 Congenital hypothyroidism without goitre
0.655 0.345 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.655 0.345 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.655 0.345 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.654 0.346 0.000
I42.2 Other hypertrophic cardiomyopathy
0.654 0.346 0.000
R34 Anuria and oliguria
0.653 0.347 0.000
J69 Pneumonitis due to solids and liquids
0.653 0.347 0.000
V80-V89 Other land transport accidents
0.652 0.348 0.000
I26 Pulmonary embolism
0.652 0.348 0.000
T78 Adverse effects, not elsewhere classified
0.652 0.348 0.000
T45.0 Antiallergic and antiemetic drugs
0.652 0.348 0.000
I46.9 Cardiac arrest, unspecified
0.651 0.349 0.000
E87.7 Fluid overload
0.651 0.349 0.000
I33 Acute and subacute endocarditis
0.650 0.349 0.000
E50-E64 Other nutritional deficiencies
0.650 0.349 0.000
X60-X84 Intentional self-harm
0.650 0.350 0.000
J98 Other respiratory disorders
0.650 0.350 0.000
B99 Other and unspecified infectious diseases
0.649 0.350 0.000
S69 Other and unspecified injuries of wrist and hand
0.649 0.351 0.000
M91-M94 Chondropathies
0.649 0.351 0.000
M60-M63 Disorders of muscles
0.649 0.351 0.000
S02.4 Fracture of malar and maxillary bones
0.648 0.352 0.000
M13.0 Polyarthritis, unspecified
0.648 0.352 0.000
J37 Chronic laryngitis and laryngotracheitis
0.647 0.353 0.000
M06.4 Inflammatory polyarthropathy
0.646 0.354 0.000
S02.3 Fracture of orbital floor
0.646 0.354 0.000
B44 Aspergillosis
0.645 0.355 0.000
H60-H62 Diseases of external ear
0.644 0.356 0.000
J33.1 Polypoid sinus degeneration
0.643 0.356 0.000
Q60-Q64 Congenital malformations of the urinary system
0.643 0.357 0.000
M14 Arthropathies in other diseases classified elsewhere
0.643 0.357 0.000
M12 Other specific arthropathies
0.643 0.357 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.643 0.357 0.000
M08 Juvenile arthritis
0.643 0.357 0.000
F32.8 Other depressive episodes
0.643 0.357 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.642 0.358 0.000
M11 Other crystal arthropathies
0.642 0.358 0.000
E85.9 Amyloidosis, unspecified
0.642 0.358 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.642 0.358 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.641 0.359 0.000
J92.9 Pleural plaque without asbestos
0.640 0.360 0.000
E16 Other disorders of pancreatic internal secretion
0.640 0.360 0.000
E05.8 Other thyrotoxicosis
0.640 0.360 0.000
E05.5 Thyroid crisis or storm
0.640 0.360 0.000
E05.4 Thyrotoxicosis factitia
0.640 0.360 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.640 0.360 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.640 0.360 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.640 0.360 0.000
T50.8 Diagnostic agents
0.638 0.362 0.000
T50.7 Analeptics and opioid receptor antagonists
0.638 0.362 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.638 0.362 0.000
T50.5 Appetite depressants
0.638 0.362 0.000
T50.4 Drugs affecting uric acid metabolism
0.638 0.362 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.638 0.362 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.638 0.362 0.000
T50.1 Loop [high-ceiling] diuretics
0.638 0.362 0.000
T50.0 Mineralocorticoids and their antagonists
0.638 0.362 0.000
S62 Fracture at wrist and hand level
0.638 0.362 0.000
R00.0 Tachycardia, unspecified
0.637 0.363 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.637 0.363 0.000
I42.8 Other cardiomyopathies
0.636 0.363 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.636 0.363 0.000
I42.6 Alcoholic cardiomyopathy
0.636 0.363 0.000
I42.5 Other restrictive cardiomyopathy
0.636 0.363 0.000
I42.4 Endocardial fibroelastosis
0.636 0.363 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.636 0.363 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.636 0.364 0.000
R27 Other lack of coordination
0.636 0.364 0.000
M40-M43 Deforming dorsopathies
0.635 0.365 0.000
S02.9 Fracture of skull and facial bones, part unspecified
0.635 0.365 0.000
S02.7 Multiple fractures involving skull and facial bones
0.635 0.365 0.000
S02.5 Fracture of tooth
0.635 0.365 0.000
S02.0 Fracture of vault of skull
0.635 0.365 0.000
I60.8 Other subarachnoid haemorrhage
0.634 0.366 0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.634 0.366 0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.634 0.366 0.000
I60.5 Subarachnoid haemorrhage from vertebral artery
0.634 0.366 0.000
I60.4 Subarachnoid haemorrhage from basilar artery
0.634 0.366 0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.634 0.366 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.634 0.366 0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.634 0.366 0.000
S61.1 Open wound of finger(s) with damage to nail
0.634 0.366 0.000
W29 Contact with other powered hand tools and household machinery
0.633 0.367 0.000
F33.8 Other recurrent depressive disorders
0.632 0.368 0.000
F33.4 Recurrent depressive disorder, currently in remission
0.632 0.368 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.632 0.368 0.000
F33.0 Recurrent depressive disorder, current episode mild
0.632 0.368 0.000
L50-L54 Urticaria and erythema
0.631 0.369 0.000
I46.1 Sudden cardiac death, so described
0.630 0.370 0.000
S65 Injury of blood vessels at wrist and hand level
0.630 0.370 0.000
M07 Psoriatic and enteropathic arthropathies
0.630 0.370 0.000
I20.8 Other forms of angina pectoris
0.630 0.370 0.000
T51.8 Other alcohols
0.628 0.372 0.000
T51.3 Fusel oil
0.628 0.372 0.000
T51.2 2-Propanol
0.628 0.372 0.000
T51.1 Methanol
0.628 0.372 0.000
E87.0 Hyperosmolality and hypernatraemia
0.628 0.372 0.000
J84 Other interstitial pulmonary diseases
0.628 0.372 0.000
B15-B19 Viral hepatitis
0.628 0.372 0.000
R22.0 Localised swelling, mass and lump, head
0.628 0.372 0.000
R74 Abnormal serum enzyme levels
0.627 0.372 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.627 0.373 0.000
L73 Other follicular disorders
0.626 0.374 0.000
I30.9 Acute pericarditis, unspecified
0.626 0.374 0.000
I09 Other rheumatic heart diseases
0.626 0.374 0.000
I06 Rheumatic aortic valve diseases
0.626 0.374 0.000
I05 Rheumatic mitral valve diseases
0.626 0.374 0.000
M13.92 Arthritis, unspecified (Upper arm)
0.625 0.375 0.000
R79.9 Abnormal finding of blood chemistry, unspecified
0.625 0.375 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.625 0.375 0.000
J92.0 Pleural plaque with presence of asbestos
0.622 0.378 0.000
E88.9 Metabolic disorder, unspecified
0.621 0.379 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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