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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs115065086
log Bayes Factor = 12.3717
Chromosome 2   position 36,397,485  (GRCh37) Explore rs115065086 on Ensembl!
Variant rs115065086 is part of Cluster X0094

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
0.998 0.002 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.997 0.003 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.995 0.005 0.000
D60-D64 Aplastic and other anaemias
0.995 0.005 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.994 0.006 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.994 0.006 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.992 0.008 0.000
Z86 Personal history of certain other diseases
0.990 0.010 0.000
Chapter II Neoplasms
0.986 0.014 0.000
Chapter XX External causes of morbidity and mortality
0.979 0.021 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.973 0.027 0.000
Z92 Personal history of medical treatment
0.970 0.030 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.969 0.031 0.000
Z86.4 Personal history of psychoactive substance abuse
0.967 0.033 0.000
D64 Other anaemias
0.967 0.033 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.966 0.034 0.000
C34 Malignant neoplasm of bronchus and lung
0.965 0.035 0.000
I60-I69 Cerebrovascular diseases
0.962 0.038 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.961 0.039 0.000
M05-M14 Inflammatory polyarthropathies
0.961 0.039 0.000
Chapter VII Diseases of the eye and adnexa
0.960 0.040 0.000
E70-E90 Metabolic disorders
0.959 0.041 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.954 0.046 0.000
Chapter XI Diseases of the digestive system
0.949 0.051 0.000
M13 Other arthritis
0.949 0.051 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.948 0.052 0.000
E20-E35 Disorders of other endocrine glands
0.948 0.052 0.000
Chapter I Certain infectious and parasitic diseases
0.947 0.053 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.947 0.053 0.000
D64.9 Anaemia, unspecified
0.946 0.054 0.000
Z98 Other postsurgical states
0.946 0.054 0.000
Z86.7 Personal history of diseases of the circulatory system
0.945 0.055 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.944 0.056 0.000
D62 Acute posthaemorrhagic anaemia
0.943 0.057 0.000
C34.3 Lower lobe, bronchus or lung
0.942 0.058 0.000
M13.9 Arthritis, unspecified
0.940 0.060 0.000
Z88.6 Personal history of allergy to analgesic agent
0.932 0.068 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.932 0.068 0.000
M65-M68 Disorders of synovium and tendon
0.930 0.070 0.000
I30-I52 Other forms of heart disease
0.928 0.072 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.927 0.073 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.918 0.082 0.000
K83 Other diseases of biliary tract
0.916 0.084 0.000
M45-M49 Spondylopathies
0.912 0.088 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.910 0.090 0.000
I26 Pulmonary embolism
0.908 0.092 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.903 0.097 0.000
C34.1 Upper lobe, bronchus or lung
0.902 0.098 0.000
Z39 Postpartum care and examination
0.900 0.100 0.000
K86 Other diseases of pancreas
0.897 0.103 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.896 0.104 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.895 0.105 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.886 0.114 0.000
E87.6 Hypokalaemia
0.883 0.117 0.000
C91 Lymphoid leukaemia
0.881 0.119 0.000
I05-I09 Chronic rheumatic heart diseases
0.880 0.120 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.880 0.120 0.000
A00-A09 Intestinal infectious diseases
0.878 0.122 0.000
E83 Disorders of mineral metabolism
0.878 0.122 0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases
0.877 0.123 0.000
M20-M25 Other joint disorders
0.876 0.124 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.875 0.125 0.000
I69 Sequelae of cerebrovascular disease
0.875 0.125 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.874 0.126 0.000
Y40 Systemic antibiotics
0.874 0.126 0.000
K83.8 Other specified diseases of biliary tract
0.871 0.129 0.000
H02 Other disorders of eyelid
0.868 0.132 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.867 0.133 0.000
Z39.0 Care and examination immediately after delivery
0.866 0.134 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.862 0.138 0.000
D80-D89 Certain disorders involving the immune mechanism
0.862 0.138 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.861 0.139 0.000
H02.8 Other specified disorders of eyelid
0.860 0.140 0.000
Z90.2 Acquired absence of lung [part of]
0.859 0.141 0.000
Z98.0 Intestinal bypass and anastomosis status
0.857 0.143 0.000
E28 Ovarian dysfunction
0.852 0.148 0.000
Z33 Pregnant state, incidental
0.852 0.148 0.000
K55-K64 Other diseases of intestines
0.852 0.148 0.000
E83.1 Disorders of iron metabolism
0.848 0.152 0.000
I67 Other cerebrovascular diseases
0.847 0.153 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.847 0.153 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.845 0.155 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.843 0.157 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.843 0.157 0.000
C78.2 Secondary malignant neoplasm of pleura
0.842 0.158 0.000
Chapter VIII Diseases of the ear and mastoid process
0.841 0.159 0.000
H55-H59 Other disorders of eye and adnexa
0.841 0.159 0.000
E87.2 Acidosis
0.839 0.161 0.000
Z86.5 Personal history of other mental and behavioural disorders
0.838 0.162 0.000
M13.94 Arthritis, unspecified (Hand)
0.834 0.166 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.833 0.167 0.000
S40-S49 Injuries to the shoulder and upper arm
0.833 0.167 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.832 0.168 0.000
K59 Other functional intestinal disorders
0.831 0.169 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.830 0.170 0.000
M65 Synovitis and tenosynovitis
0.828 0.172 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.826 0.174 0.000
M25 Other joint disorders, not elsewhere classified
0.825 0.175 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.824 0.176 0.000
K85 Acute pancreatitis
0.824 0.176 0.000
S90-S99 Injuries to the ankle and foot
0.821 0.179 0.000
C91.1 Chronic lymphocytic leukaemia
0.819 0.181 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.819 0.181 0.000
K59.0 Constipation
0.819 0.181 0.000
M47 Spondylosis
0.814 0.186 0.000
K80 Cholelithiasis
0.814 0.186 0.000
M67 Other disorders of synovium and tendon
0.814 0.186 0.000
I69.3 Sequelae of cerebral infarction
0.810 0.190 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.809 0.191 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.808 0.192 0.000
E65-E68 Obesity and other hyperalimentation
0.808 0.192 0.000
K35-K38 Diseases of appendix
0.807 0.193 0.000
K83.0 Cholangitis
0.807 0.193 0.000
Z36 Antenatal screening
0.806 0.194 0.000
I44 Atrioventricular and left bundle-branch block
0.800 0.200 0.000
I45 Other conduction disorders
0.800 0.200 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.799 0.201 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.798 0.202 0.000
K82 Other diseases of gallbladder
0.798 0.202 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.796 0.204 0.000
A30-A49 Other bacterial diseases
0.795 0.205 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.794 0.206 0.000
E27 Other disorders of adrenal gland
0.794 0.206 0.000
M25.5 Pain in joint
0.791 0.209 0.000
Y42.7 Androgens and anabolic congeners
0.789 0.211 0.000
Z88.5 Personal history of allergy to narcotic agent
0.786 0.214 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.785 0.215 0.000
Z98.8 Other specified postsurgical states
0.784 0.216 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.784 0.216 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.783 0.217 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.783 0.217 0.000
E28.2 Polycystic ovarian syndrome
0.783 0.217 0.000
A80-A89 Viral infections of the central nervous system
0.783 0.217 0.000
M80-M85 Disorders of bone density and structure
0.780 0.219 0.000
K86.3 Pseudocyst of pancreas
0.780 0.220 0.000
I07 Rheumatic tricuspid valve diseases
0.780 0.220 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.780 0.220 0.000
E16 Other disorders of pancreatic internal secretion
0.777 0.223 0.000
Chapter VI Diseases of the nervous system
0.776 0.224 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.776 0.224 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.772 0.228 0.000
Z09.9 Follow-up examination after unspecified treatment for other conditions
0.771 0.229 0.000
I38 Endocarditis, valve unspecified
0.771 0.229 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.771 0.229 0.000
I27 Other pulmonary heart diseases
0.769 0.231 0.000
B99-B99 Other infectious diseases
0.769 0.231 0.000
Z34 Supervision of normal pregnancy
0.769 0.231 0.000
H10-H13 Disorders of conjunctiva
0.768 0.232 0.000
I67.8 Other specified cerebrovascular diseases
0.768 0.232 0.000
M46 Other inflammatory spondylopathies
0.767 0.232 0.000
D61 Other aplastic anaemias
0.767 0.233 0.000
V80-V89 Other land transport accidents
0.767 0.233 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.765 0.235 0.000
K37 Unspecified appendicitis
0.765 0.235 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.765 0.235 0.000
D63.8 Anaemia in other chronic diseases classified elsewhere
0.763 0.237 0.000
E87.5 Hyperkalaemia
0.762 0.238 0.000
H02.1 Ectropion of eyelid
0.762 0.238 0.000
T43.2 Other and unspecified antidepressants
0.761 0.239 0.000
Z98.1 Arthrodesis status
0.760 0.240 0.000
E50-E64 Other nutritional deficiencies
0.759 0.240 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.759 0.241 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.758 0.242 0.000
A04 Other bacterial intestinal infections
0.757 0.243 0.000
K65-K67 Diseases of peritoneum
0.757 0.243 0.000
V40-V49 Car occupant injured in transport accident
0.756 0.243 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.756 0.244 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.756 0.244 0.000
M14 Arthropathies in other diseases classified elsewhere
0.756 0.244 0.000
I51 Complications and ill-defined descriptions of heart disease
0.753 0.247 0.000
Z87 Personal history of other diseases and conditions
0.753 0.247 0.000
Y42.5 Other oestrogens and progestogens
0.752 0.248 0.000
E24 Cushing's syndrome
0.752 0.248 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.751 0.249 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.751 0.249 0.000
W00-W19 Falls
0.750 0.249 0.000
Y40.0 Penicillins
0.749 0.251 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.748 0.251 0.000
W50-W64 Exposure to animate mechanical forces
0.748 0.252 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.747 0.252 0.000
H02.5 Other disorders affecting eyelid function
0.746 0.254 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.745 0.255 0.000
K86.8 Other specified diseases of pancreas
0.745 0.255 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.745 0.255 0.000
Z84 Family history of other conditions
0.745 0.255 0.000
H55 Nystagmus and other irregular eye movements
0.744 0.256 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.744 0.256 0.000
M91-M94 Chondropathies
0.744 0.256 0.000
K82.4 Cholesterolosis of gallbladder
0.743 0.257 0.000
E85 Amyloidosis
0.742 0.258 0.000
D86 Sarcoidosis
0.742 0.258 0.000
Z90.3 Acquired absence of part of stomach
0.742 0.258 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.740 0.260 0.000
C15-C26 Malignant neoplasms of digestive organs
0.739 0.261 0.000
M31 Other necrotising vasculopathies
0.738 0.262 0.000
I33 Acute and subacute endocarditis
0.737 0.263 0.000
I62 Other nontraumatic intracranial haemorrhage
0.737 0.263 0.000
Z31 Procreative management
0.736 0.264 0.000
Z97 Presence of other devices
0.736 0.264 0.000
Z89 Acquired absence of limb
0.736 0.264 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.735 0.265 0.000
I37 Pulmonary valve disorders
0.734 0.265 0.000
M60-M63 Disorders of muscles
0.734 0.266 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.734 0.266 0.000
I61 Intracerebral haemorrhage
0.734 0.266 0.000
K86.1 Other chronic pancreatitis
0.732 0.268 0.000
H18 Other disorders of cornea
0.732 0.268 0.000
S10-S19 Injuries to the neck
0.732 0.268 0.000
H50 Other strabismus
0.731 0.269 0.000
I50 Heart failure
0.731 0.269 0.000
K85.9 Acute pancreatitis, unspecified
0.729 0.271 0.000
X50-X57 Overexertion, travel and privation
0.728 0.272 0.000
Z60 Problems related to social environment
0.728 0.272 0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.728 0.272 0.000
M48 Other spondylopathies
0.726 0.274 0.000
B65-B83 Helminthiases
0.726 0.274 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.726 0.274 0.000
A08 Viral and other specified intestinal infections
0.725 0.275 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.724 0.276 0.000
K56.6 Other and unspecified intestinal obstruction
0.724 0.276 0.000
M00-M03 Infectious arthropathies
0.721 0.279 0.000
E87.0 Hyperosmolality and hypernatraemia
0.721 0.279 0.000
S70-S79 Injuries to the hip and thigh
0.720 0.280 0.000
H90-H95 Other disorders of ear
0.720 0.280 0.000
X60-X84 Intentional self-harm
0.719 0.281 0.000
Z72 Problems related to lifestyle
0.719 0.281 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.719 0.281 0.000
Z81 Family history of mental and behavioural disorders
0.718 0.282 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.717 0.283 0.000
I60 Subarachnoid haemorrhage
0.716 0.284 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.716 0.284 0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.716 0.284 0.000
M11 Other crystal arthropathies
0.715 0.285 0.000
I00-I02 Acute rheumatic fever
0.715 0.285 0.000
Z09.0 Follow-up examination after surgery for other conditions
0.715 0.285 0.000
D55-D59 Haemolytic anaemias
0.715 0.285 0.000
T79-T79 Certain early complications of trauma
0.714 0.286 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.714 0.286 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.713 0.287 0.000
M47.8 Other spondylosis
0.712 0.288 0.000
E16.2 Hypoglycaemia, unspecified
0.712 0.288 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.712 0.288 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.711 0.289 0.000
K86.0 Alcohol-induced chronic pancreatitis
0.711 0.289 0.000
E88 Other metabolic disorders
0.709 0.291 0.000
Y52 Agents primarily affecting the cardiovascular system
0.708 0.292 0.000
I07.1 Tricuspid insufficiency
0.708 0.292 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.707 0.293 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.707 0.293 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.707 0.293 0.000
M25.8 Other specified joint disorders
0.707 0.293 0.000
Z36.9 Antenatal screening, unspecified
0.706 0.294 0.000
Y40.9 Systemic antibiotic, unspecified
0.705 0.295 0.000
K56.5 Intestinal adhesions [bands] with obstruction
0.704 0.296 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.704 0.296 0.000
D63.0 Anaemia in neoplastic disease
0.703 0.297 0.000
M67.8 Other specified disorders of synovium and tendon
0.703 0.297 0.000
Y35-Y36 Legal intervention and operations of war
0.702 0.298 0.000
Y10-Y34 Event of undetermined intent
0.702 0.298 0.000
Y00-Y09 Assault
0.702 0.298 0.000
X85-X99 Assault
0.702 0.298 0.000
X30-X39 Exposure to forces of nature
0.702 0.298 0.000
X20-X29 Contact with venomous animals and plants
0.702 0.298 0.000
X10-X19 Contact with heat and hot substances
0.702 0.298 0.000
X00-X09 Exposure to smoke, fire and flames
0.702 0.298 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.702 0.298 0.000
W75-W84 Other accidental threats to breathing
0.702 0.298 0.000
W65-W74 Accidental drowning and submersion
0.702 0.298 0.000
V98-V99 Other and unspecified transport accidents
0.702 0.298 0.000
V95-V97 Air and space transport accidents
0.702 0.298 0.000
V90-V94 Water transport accidents
0.702 0.298 0.000
V70-V79 Bus occupant injured in transport accident
0.702 0.298 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.702 0.298 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.702 0.298 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.702 0.298 0.000
V01-V09 Pedestrian injured in transport accident
0.702 0.298 0.000
M13.0 Polyarthritis, unspecified
0.702 0.298 0.000
H05 Disorders of orbit
0.701 0.299 0.000
H16 Keratitis
0.700 0.300 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.698 0.302 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.698 0.302 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.698 0.302 0.000
C31 Malignant neoplasm of accessory sinuses
0.698 0.302 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.698 0.302 0.000
C37 Malignant neoplasm of thymus
0.698 0.302 0.000
C33 Malignant neoplasm of trachea
0.698 0.302 0.000
M86-M90 Other osteopathies
0.697 0.302 0.000
C91.4 Hairy-cell leukaemia
0.697 0.303 0.000
W20-W49 Exposure to inanimate mechanical forces
0.697 0.303 0.000
Z92.8 Personal history of other medical treatment
0.697 0.303 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.697 0.303 0.000
Z92.9 Personal history of medical treatment, unspecified
0.695 0.305 0.000
Z92.5 Personal history of rehabilitation measures
0.695 0.305 0.000
T33-T35 Frostbite
0.695 0.305 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.695 0.305 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.695 0.305 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.695 0.305 0.000
T00-T07 Injuries involving multiple body regions
0.695 0.305 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.694 0.306 0.000
K80.4 Calculus of bile duct with cholecystitis
0.693 0.306 0.000
T66-T78 Other and unspecified effects of external causes
0.693 0.307 0.000
D64.8 Other specified anaemias
0.693 0.307 0.000
D64.4 Congenital dyserythropoietic anaemia
0.693 0.307 0.000
D64.3 Other sideroblastic anaemias
0.693 0.307 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.693 0.307 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.693 0.307 0.000
D64.0 Hereditary sideroblastic anaemia
0.693 0.307 0.000
K80.0 Calculus of gallbladder with acute cholecystitis
0.693 0.307 0.000
Y59 Other and unspecified vaccines and biological substances
0.693 0.307 0.000
Y58 Bacterial vaccines
0.693 0.307 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.693 0.307 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.693 0.307 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.693 0.307 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.693 0.307 0.000
Y48 Anaesthetics and therapeutic gases
0.693 0.307 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.693 0.307 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.693 0.307 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.693 0.307 0.000
C34.8 Overlapping lesion of bronchus and lung
0.692 0.308 0.000
C34.2 Middle lobe, bronchus or lung
0.692 0.308 0.000
C34.0 Main bronchus
0.692 0.308 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.691 0.309 0.000
S42 Fracture of shoulder and upper arm
0.691 0.309 0.000
E87.3 Alkalosis
0.691 0.309 0.000
Y45.0 Opioids and related analgesics
0.691 0.309 0.000
C83.3 Large cell (diffuse)
0.691 0.309 0.000
I74 Arterial embolism and thrombosis
0.690 0.310 0.000
H60-H62 Diseases of external ear
0.690 0.310 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.690 0.310 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.690 0.310 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.689 0.311 0.000
I34 Nonrheumatic mitral valve disorders
0.689 0.311 0.000
M12 Other specific arthropathies
0.689 0.311 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.689 0.311 0.000
M08 Juvenile arthritis
0.689 0.311 0.000
E40-E46 Malnutrition
0.688 0.312 0.000
E84 Cystic fibrosis
0.687 0.313 0.000
E79 Disorders of purine and pyrimidine metabolism
0.687 0.313 0.000
E77 Disorders of glycoprotein metabolism
0.687 0.313 0.000
E76 Disorders of glycosaminoglycan metabolism
0.687 0.313 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.687 0.313 0.000
E74 Other disorders of carbohydrate metabolism
0.687 0.313 0.000
E73 Lactose intolerance
0.687 0.313 0.000
E72 Other disorders of amino-acid metabolism
0.687 0.313 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.687 0.313 0.000
E70 Disorders of aromatic amino-acid metabolism
0.687 0.313 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.687 0.313 0.000
Y40.1 Cefalosporins and other -lactam antibiotics
0.687 0.313 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.687 0.313 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.687 0.313 0.000
K56.4 Other impaction of intestine
0.687 0.313 0.000
E87.7 Fluid overload
0.687 0.313 0.000
I28 Other diseases of pulmonary vessels
0.684 0.316 0.000
I42 Cardiomyopathy
0.684 0.316 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.683 0.317 0.000
C32 Malignant neoplasm of larynx
0.682 0.318 0.000
I72 Other aneurysm
0.681 0.319 0.000
S20-S29 Injuries to the thorax
0.681 0.319 0.000
C51-C58 Malignant neoplasms of female genital organs
0.681 0.319 0.000
M13.8 Other specified arthritis
0.680 0.320 0.000
M13.1 Monoarthritis, not elsewhere classified
0.680 0.320 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.680 0.320 0.000
Z72.1 Alcohol use
0.680 0.320 0.000
V20-V29 Motorcycle rider injured in transport accident
0.680 0.320 0.000
C81 Hodgkin's disease
0.680 0.320 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.679 0.320 0.000
E34 Other endocrine disorders
0.679 0.320 0.000
E32 Diseases of thymus
0.679 0.320 0.000
E31 Polyglandular dysfunction
0.679 0.320 0.000
E30 Disorders of puberty, not elsewhere classified
0.679 0.320 0.000
E26 Hyperaldosteronism
0.679 0.320 0.000
E25 Adrenogenital disorders
0.679 0.320 0.000
E22 Hyperfunction of pituitary gland
0.679 0.320 0.000
E20 Hypoparathyroidism
0.679 0.320 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.679 0.321 0.000
B50-B64 Protozoal diseases
0.679 0.321 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.679 0.321 0.000
B15-B19 Viral hepatitis
0.679 0.321 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.679 0.321 0.000
A75-A79 Rickettsioses
0.679 0.321 0.000
A70-A74 Other diseases caused by chlamydiae
0.679 0.321 0.000
A65-A69 Other spirochaetal diseases
0.679 0.321 0.000
A20-A28 Certain zoonotic bacterial diseases
0.679 0.321 0.000
A15-A19 Tuberculosis
0.679 0.321 0.000
Z38 Liveborn infants according to place of birth
0.679 0.321 0.000
Z32 Pregnancy examination and test
0.679 0.321 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.678 0.322 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.677 0.323 0.000
C95 Leukaemia of unspecified cell type
0.677 0.323 0.000
C94 Other leukaemias of specified cell type
0.677 0.323 0.000
C93 Monocytic leukaemia
0.677 0.323 0.000
C88 Malignant immunoproliferative diseases
0.677 0.323 0.000
C86 Other specified types of T/NK-cell lymphoma
0.677 0.323 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.677 0.323 0.000
M25.52 Pain in joint (Upper arm)
0.677 0.323 0.000
M24 Other specific joint derangements
0.676 0.324 0.000
Z34.0 Supervision of normal first pregnancy
0.675 0.325 0.000
I08 Multiple valve diseases
0.674 0.326 0.000
E66 Obesity
0.674 0.326 0.000
I44.7 Left bundle-branch block, unspecified
0.674 0.326 0.000
Z22 Carrier of infectious disease
0.674 0.326 0.000
M13.93 Arthritis, unspecified (Forearm)
0.674 0.326 0.000
M13.92 Arthritis, unspecified (Upper arm)
0.674 0.326 0.000
I67.9 Cerebrovascular disease, unspecified
0.673 0.326 0.000
C92 Myeloid leukaemia
0.673 0.327 0.000
A04.8 Other specified bacterial intestinal infections
0.673 0.327 0.000
Z98.2 Presence of cerebrospinal fluid drainage device
0.672 0.328 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.671 0.329 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.671 0.329 0.000
S36 Injury of intra-abdominal organs
0.671 0.329 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.671 0.329 0.000
Chapter XXII Codes for special purposes
0.670 0.330 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.670 0.330 0.000
D80 Immunodeficiency with predominantly antibody defects
0.669 0.331 0.000
E29 Testicular dysfunction
0.669 0.331 0.000
I20-I25 Ischaemic heart diseases
0.669 0.331 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.668 0.332 0.000
E87.4 Mixed disorder of acid-base balance
0.668 0.332 0.000
H20 Iridocyclitis
0.668 0.332 0.000
K86.9 Disease of pancreas, unspecified
0.667 0.333 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.667 0.333 0.000
M66 Spontaneous rupture of synovium and tendon
0.667 0.333 0.000
Z02 Examination and encounter for administrative purposes
0.667 0.333 0.000
C79 Secondary malignant neoplasm of other sites
0.666 0.334 0.000
I52 Other heart disorders in diseases classified elsewhere
0.665 0.335 0.000
I48 Atrial fibrillation and flutter
0.665 0.335 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.665 0.335 0.000
I41 Myocarditis in diseases classified elsewhere
0.665 0.335 0.000
I40 Acute myocarditis
0.665 0.335 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.665 0.335 0.000
I36 Nonrheumatic tricuspid valve disorders
0.665 0.335 0.000
I32 Pericarditis in diseases classified elsewhere
0.665 0.335 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.665 0.335 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.664 0.336 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.664 0.336 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.664 0.336 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.664 0.336 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.664 0.336 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.664 0.336 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.664 0.336 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.664 0.336 0.000
T36 Poisoning by systemic antibiotics
0.664 0.336 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.664 0.336 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.663 0.337 0.000
Z83 Family history of other specific disorders
0.663 0.337 0.000
M25.57 Pain in joint (Ankle and foot)
0.663 0.337 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.662 0.338 0.000
M07 Psoriatic and enteropathic arthropathies
0.661 0.338 0.000
I50.1 Left ventricular failure
0.661 0.339 0.000
Z94 Transplanted organ and tissue status
0.660 0.340 0.000
M25.51 Pain in joint (Shoulder region)
0.660 0.340 0.000
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities
0.660 0.340 0.000
Z12 Special screening examination for neoplasms
0.660 0.340 0.000
I30 Acute pericarditis
0.659 0.340 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.659 0.340 0.000
H02.3 Blepharochalasis
0.659 0.341 0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified
0.659 0.341 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.657 0.343 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.657 0.343 0.000
K83.9 Disease of biliary tract, unspecified
0.657 0.343 0.000
K83.5 Biliary cyst
0.657 0.343 0.000
K83.4 Spasm of sphincter of Oddi
0.657 0.343 0.000
K83.3 Fistula of bile duct
0.657 0.343 0.000
K83.2 Perforation of bile duct
0.657 0.343 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.657 0.343 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.656 0.343 0.000
Z87.4 Personal history of diseases of the genito-urinary system
0.656 0.344 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.655 0.344 0.000
Z29 Need for other prophylactic measures
0.655 0.345 0.000
H50.9 Strabismus, unspecified
0.655 0.345 0.000
Z93 Artificial opening status
0.655 0.345 0.000
K59.8 Other specified functional intestinal disorders
0.655 0.345 0.000
E10-E14 Diabetes mellitus
0.654 0.346 0.000
M49 Spondylopathies in diseases classified elsewhere
0.654 0.346 0.000
Z75 Problems related to medical facilities and other health care
0.653 0.347 0.000
Y42.9 Other and unspecified hormone antagonists
0.653 0.347 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.653 0.347 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.653 0.347 0.000
Y42.4 Oral contraceptives
0.653 0.347 0.000
Y42.2 Antithyroid drugs
0.653 0.347 0.000
Y42.1 Thyroid hormones and substitutes
0.653 0.347 0.000
I70 Atherosclerosis
0.653 0.347 0.000
Z39.1 Care and examination of lactating mother
0.652 0.347 0.000
C34.9 Bronchus or lung, unspecified
0.652 0.348 0.000
C83.0 Small cell (diffuse)
0.652 0.348 0.000
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods
0.651 0.349 0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.651 0.349 0.000
V10-V19 Pedal cyclist injured in transport accident
0.650 0.349 0.000
K80.1 Calculus of gallbladder with other cholecystitis
0.650 0.350 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.650 0.350 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.649 0.351 0.000
I45.4 Nonspecific intraventricular block
0.649 0.351 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.649 0.351 0.000
I44.0 Atrioventricular block, first degree
0.648 0.352 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.646 0.353 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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