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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1150691
log Bayes Factor = 56.6716
Chromosome 6   position 28,168,033  (GRCh37) Explore rs1150691 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
K90.0 Coeliac disease
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
0.959 0.041 0.000
E10.9 Without complications
0.957 0.043 0.000
E10-E14 Diabetes mellitus
0.951 0.049 0.000
E16.2 Hypoglycaemia, unspecified
0.949 0.051 0.000
E16 Other disorders of pancreatic internal secretion
0.945 0.055 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.943 0.057 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.943 0.057 0.000
E05.9 Thyrotoxicosis, unspecified
0.921 0.079 0.000
R31 Unspecified haematuria
0.000 0.079 0.921
E05 Thyrotoxicosis [hyperthyroidism]
0.916 0.084 0.000
E00-E07 Disorders of thyroid gland
0.913 0.087 0.000
E14 Unspecified diabetes mellitus
0.898 0.102 0.000
E10.3 With ophthalmic complications
0.871 0.129 0.000
E10.1 With ketoacidosis
0.837 0.163 0.000
E10.2 With renal complications
0.811 0.189 0.000
E10.6 With other specified complications
0.808 0.192 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.792 0.208 0.000
E20-E35 Disorders of other endocrine glands
0.781 0.219 0.000
E10.5 With peripheral circulatory complications
0.779 0.221 0.000
E14.4 With neurological complications
0.742 0.257 0.000
E14.9 Without complications
0.741 0.259 0.000
E14.1 With ketoacidosis
0.730 0.270 0.000
E14.6 With other specified complications
0.718 0.282 0.000
E10.7 With multiple complications
0.712 0.288 0.000
E10.0 With coma
0.710 0.290 0.000
E14.5 With peripheral circulatory complications
0.690 0.310 0.000
E14.3 With ophthalmic complications
0.689 0.311 0.000
K90 Intestinal malabsorption
0.688 0.312 0.000
E12 Malnutrition-related diabetes mellitus
0.682 0.318 0.000
E40-E46 Malnutrition
0.682 0.318 0.000
E16.1 Other hypoglycaemia
0.681 0.319 0.000
E14.2 Withrenal complications
0.678 0.322 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.678 0.322 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.678 0.322 0.000
E16.4 Abnormal secretion of gastrin
0.678 0.322 0.000
E16.3 Increased secretion of glucagon
0.678 0.322 0.000
E15 Nondiabetic hypoglycaemic coma
0.676 0.324 0.000
E23 Hypofunction and other disorders of pituitary gland
0.675 0.325 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.669 0.331 0.000
E24 Cushing's syndrome
0.660 0.340 0.000
E05.5 Thyroid crisis or storm
0.657 0.343 0.000
E05.4 Thyrotoxicosis factitia
0.657 0.343 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.657 0.343 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.657 0.343 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.655 0.345 0.000
E00 Congenital iodine-deficiency syndrome
0.655 0.345 0.000
E05.8 Other thyrotoxicosis
0.651 0.349 0.000
E20 Hypoparathyroidism
0.644 0.356 0.000
E14.7 With multiple complications
0.644 0.356 0.000
E14.0 With coma
0.644 0.356 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.627 0.373 0.000
E27 Other disorders of adrenal gland
0.623 0.377 0.000
E13 Other specified diabetes mellitus
0.621 0.379 0.000
E31 Polyglandular dysfunction
0.605 0.395 0.000
E07 Other disorders of thyroid
0.598 0.401 0.000
E23.2 Diabetes insipidus
0.589 0.411 0.000
E29 Testicular dysfunction
0.585 0.415 0.000
E10.4 With neurological complications
0.567 0.433 0.000
E27.1 Primary adrenocortical insufficiency
0.565 0.435 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.562 0.438 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.560 0.440 0.000
E32 Diseases of thymus
0.560 0.440 0.000
E30 Disorders of puberty, not elsewhere classified
0.560 0.440 0.000
E25 Adrenogenital disorders
0.560 0.440 0.000
E24.2 Drug-induced Cushing's syndrome
0.559 0.441 0.000
E28 Ovarian dysfunction
0.547 0.453 0.000
E24.0 Pituitary-dependent Cushing's disease
0.546 0.454 0.000
E14.8 With unspecified complications
0.533 0.467 0.000
E20.9 Hypoparathyroidism, unspecified
0.528 0.472 0.000
E23.0 Hypopituitarism
0.517 0.483 0.000
K90.8 Other intestinal malabsorption
0.517 0.483 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.505 0.495 0.000
E23.6 Other disorders of pituitary gland
0.498 0.502 0.000
E07.8 Other specified disorders of thyroid
0.496 0.504 0.000
E46 Unspecified protein-energy malnutrition
0.494 0.506 0.000
K90.3 Pancreatic steatorrhoea
0.493 0.506 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.493 0.506 0.000
K90.1 Tropical sprue
0.493 0.506 0.000
E20.8 Other hypoparathyroidism
0.491 0.509 0.000
E06 Thyroiditis
0.489 0.510 0.001
E12.9 Without complications
0.489 0.511 0.000
E12.8 With unspecified complications
0.489 0.511 0.000
E12.7 With multiple complications
0.489 0.511 0.000
E12.6 With other specified complications
0.489 0.511 0.000
E12.5 With peripheral circulatory complications
0.489 0.511 0.000
E12.4 With neurological complications
0.489 0.511 0.000
E12.3 With ophthalmic complications
0.489 0.511 0.000
E12.2 With renal complications
0.489 0.511 0.000
E12.1 With ketoacidosis
0.489 0.511 0.000
E12.0 With coma
0.489 0.511 0.000
E22 Hyperfunction of pituitary gland
0.489 0.511 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.489 0.511 0.000
E45 Retarded development following protein-energy malnutrition
0.489 0.511 0.000
E43 Unspecified severe protein-energy malnutrition
0.489 0.511 0.000
E42 Marasmic kwashiorkor
0.489 0.511 0.000
E41 Nutritional marasmus
0.489 0.511 0.000
E40 Kwashiorkor
0.489 0.511 0.000
E27.2 Addisonian crisis
0.484 0.516 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.484 0.516 0.000
E23.1 Drug-induced hypopituitarism
0.484 0.516 0.000
E10.8 With unspecified complications
0.479 0.520 0.000
E31.0 Autoimmune polyglandular failure
0.478 0.521 0.000
E24.8 Other Cushing's syndrome
0.473 0.527 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.473 0.527 0.000
E24.3 Ectopic ACTH syndrome
0.473 0.527 0.000
E24.1 Nelson's syndrome
0.473 0.527 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.469 0.530 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.469 0.530 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.469 0.530 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.469 0.530 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.469 0.530 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.469 0.530 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.469 0.530 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.469 0.530 0.000
E20.1 Pseudohypoparathyroidism
0.462 0.538 0.000
E20.0 Idiopathic hypoparathyroidism
0.462 0.538 0.000
E34 Other endocrine disorders
0.453 0.547 0.000
E23.7 Disorder of pituitary gland, unspecified
0.453 0.547 0.000
E27.5 Adrenomedullary hyperfunction
0.446 0.553 0.000
E27.0 Other adrenocortical overactivity
0.446 0.553 0.000
E13.8 With unspecified complications
0.445 0.554 0.000
E13.7 With multiple complications
0.445 0.554 0.000
E13.6 With other specified complications
0.445 0.554 0.000
E13.5 With peripheral circulatory complications
0.445 0.554 0.000
E13.4 With neurological complications
0.445 0.554 0.000
E13.2 With renal complications
0.445 0.554 0.000
E13.1 With ketoacidosis
0.445 0.554 0.000
E13.0 With coma
0.445 0.554 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.445 0.555 0.000
K90.9 Intestinal malabsorption, unspecified
0.445 0.555 0.000
E29.1 Testicular hypofunction
0.442 0.558 0.000
E26 Hyperaldosteronism
0.441 0.558 0.000
E31.9 Polyglandular dysfunction, unspecified
0.434 0.566 0.000
E31.8 Other polyglandular dysfunction
0.434 0.566 0.000
E31.1 Polyglandular hyperfunction
0.434 0.566 0.000
E07.1 Dyshormogenetic goitre
0.429 0.571 0.000
E07.0 Hypersecretion of calcitonin
0.429 0.571 0.000
E29.9 Testicular dysfunction, unspecified
0.421 0.578 0.000
E13.9 Without complications
0.420 0.580 0.000
E29.8 Other testicular dysfunction
0.419 0.581 0.000
E29.0 Testicular hyperfunction
0.419 0.581 0.000
E13.3 With ophthalmic complications
0.415 0.585 0.000
E83 Disorders of mineral metabolism
0.000 0.587 0.412
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.411 0.589 0.000
E28.3 Primary ovarian failure
0.408 0.592 0.000
E30.9 Disorder of puberty, unspecified
0.401 0.598 0.000
E30.8 Other disorders of puberty
0.401 0.598 0.000
E30.1 Precocious puberty
0.401 0.598 0.000
E30.0 Delayed puberty
0.401 0.598 0.000
E32.9 Disease of thymus, unspecified
0.401 0.598 0.000
E32.8 Other diseases of thymus
0.401 0.598 0.000
E32.1 Abscess of thymus
0.401 0.598 0.000
E32.0 Persistent hyperplasia of thymus
0.401 0.598 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.401 0.598 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.401 0.598 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.401 0.598 0.000
E25.9 Adrenogenital disorder, unspecified
0.401 0.598 0.000
E25.8 Other adrenogenital disorders
0.401 0.598 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.401 0.598 0.000
E50-E64 Other nutritional deficiencies
0.397 0.603 0.000
E24.9 Cushing's syndrome, unspecified
0.396 0.604 0.000
E28.9 Ovarian dysfunction, unspecified
0.392 0.608 0.000
E28.8 Other ovarian dysfunction
0.392 0.608 0.000
E28.1 Androgen excess
0.392 0.608 0.000
E28.0 Oestrogen excess
0.392 0.608 0.000
E83.3 Disorders of phosphorus metabolism
0.000 0.614 0.386
E06.9 Thyroiditis, unspecified
0.383 0.617 0.000
E27.9 Disorder of adrenal gland, unspecified
0.363 0.637 0.000
E28.2 Polycystic ovarian syndrome
0.360 0.640 0.000
E06.5 Other chronic thyroiditis
0.357 0.642 0.001
E06.4 Drug-induced thyroiditis
0.351 0.649 0.001
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.351 0.649 0.001
E06.1 Subacute thyroiditis
0.351 0.649 0.001
E06.0 Acute thyroiditis
0.351 0.649 0.001
E22.9 Hyperfunction of pituitary gland, unspecified
0.350 0.649 0.000
E22.8 Other hyperfunction of pituitary gland
0.350 0.649 0.000
E44.1 Mild protein-energy malnutrition
0.350 0.649 0.000
E44.0 Moderate protein-energy malnutrition
0.350 0.649 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.348 0.651 0.001
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.342 0.658 0.000
E34.9 Endocrine disorder, unspecified
0.331 0.669 0.000
E34.3 Short stature, not elsewhere classified
0.330 0.670 0.000
E34.5 Androgen resistance syndrome
0.325 0.675 0.000
E34.4 Constitutional tall stature
0.325 0.675 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.325 0.675 0.000
E34.1 Other hypersecretion of intestinal hormones
0.325 0.675 0.000
E26.9 Hyperaldosteronism, unspecified
0.316 0.683 0.000
E26.8 Other hyperaldosteronism
0.316 0.683 0.000
E26.1 Secondary hyperaldosteronism
0.316 0.683 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.696 0.304
E03 Other hypothyroidism
0.298 0.702 0.000
E56 Other vitamin deficiencies
0.297 0.703 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.704 0.296
E83.8 Other disorders of mineral metabolism
0.000 0.704 0.296
E83.2 Disorders of zinc metabolism
0.000 0.704 0.296
E83.0 Disorders of copper metabolism
0.000 0.704 0.296
E64 Sequelae of malnutrition and other nutritional deficiencies
0.284 0.715 0.000
E63 Other nutritional deficiencies
0.284 0.715 0.000
E50 Vitamin A deficiency
0.284 0.715 0.000
E60 Dietary zinc deficiency
0.284 0.715 0.000
E59 Dietary selenium deficiency
0.284 0.715 0.000
E54 Ascorbic acid deficiency
0.284 0.715 0.000
E52 Niacin deficiency [pellagra]
0.284 0.715 0.000
E34.8 Other specified endocrine disorders
0.283 0.717 0.000
E22.1 Hyperprolactinaemia
0.281 0.719 0.000
E51 Thiamine deficiency
0.270 0.729 0.000
E65-E68 Obesity and other hyperalimentation
0.267 0.733 0.000
E58 Dietary calcium deficiency
0.261 0.739 0.000
E21.4 Other specified disorders of parathyroid gland
0.261 0.739 0.000
E34.0 Carcinoid syndrome
0.261 0.739 0.000
E21.3 Hyperparathyroidism, unspecified
0.258 0.742 0.000
E61 Deficiency of other nutrient elements
0.252 0.748 0.000
E53 Deficiency of other B group vitamins
0.249 0.751 0.000
E21.2 Other hyperparathyroidism
0.247 0.753 0.000
E83.4 Disorders of magnesium metabolism
0.000 0.756 0.244
E22.0 Acromegaly and pituitary gigantism
0.242 0.758 0.000
E56.1 Deficiency of vitamin K
0.226 0.774 0.000
E07.9 Disorder of thyroid, unspecified
0.225 0.775 0.000
E03.5 Myxoedema coma
0.214 0.786 0.000
E03.4 Atrophy of thyroid (acquired)
0.214 0.786 0.000
E03.3 Postinfectious hypothyroidism
0.214 0.786 0.000
E03.1 Congenital hypothyroidism without goitre
0.214 0.786 0.000
E56.9 Vitamin deficiency, unspecified
0.213 0.787 0.000
E56.8 Deficiency of other vitamins
0.213 0.787 0.000
E56.0 Deficiency of vitamin E
0.213 0.787 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.213 0.787 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.211 0.789 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.209 0.791 0.000
E55 Vitamin D deficiency
0.206 0.794 0.000
E50.9 Vitamin A deficiency, unspecified
0.204 0.796 0.000
E50.8 Other manifestations of vitamin A deficiency
0.204 0.796 0.000
E50.7 Other ocular manifestations of vitamin A deficiency
0.204 0.796 0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.204 0.796 0.000
E50.5 Vitamin A deficiency with night blindness
0.204 0.796 0.000
E50.4 Vitamin A deficiency with keratomalacia
0.204 0.796 0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.204 0.796 0.000
E50.2 Vitamin A deficiency with corneal xerosis
0.204 0.796 0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.204 0.796 0.000
E50.0 Vitamin A deficiency with conjunctival xerosis
0.204 0.796 0.000
E63.9 Nutritional deficiency, unspecified
0.204 0.796 0.000
E63.8 Other specified nutritional deficiencies
0.204 0.796 0.000
E63.1 Imbalance of constituents of food intake
0.204 0.796 0.000
E63.0 Essential fatty acid [EFA] deficiency
0.204 0.796 0.000
E64.9 Sequelae of unspecified nutritional deficiency
0.204 0.796 0.000
E64.8 Sequelae of other nutritional deficiencies
0.204 0.796 0.000
E64.3 Sequelae of rickets
0.204 0.796 0.000
E64.2 Sequelae of vitamin C deficiency
0.204 0.796 0.000
E64.1 Sequelae of vitamin A deficiency
0.204 0.796 0.000
E64.0 Sequelae of protein-energy malnutrition
0.204 0.796 0.000
E26.0 Primary hyperaldosteronism
0.198 0.802 0.001
E51.9 Thiamine deficiency, unspecified
0.194 0.806 0.000
E51.8 Other manifestations of thiamine deficiency
0.194 0.806 0.000
E51.1 Beriberi
0.194 0.806 0.000
E67 Other hyperalimentation
0.191 0.808 0.000
E68 Sequelae of hyperalimentation
0.191 0.808 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.191 0.808 0.000
E61.1 Iron deficiency
0.182 0.818 0.000
E61.9 Deficiency of nutrient element, unspecified
0.180 0.819 0.000
E61.8 Deficiency of other specified nutrient elements
0.180 0.819 0.000
E61.7 Deficiency of multiple nutrient elements
0.180 0.819 0.000
E61.6 Vanadium deficiency
0.180 0.819 0.000
E61.5 Molybdenum deficiency
0.180 0.819 0.000
E61.4 Chromium deficiency
0.180 0.819 0.000
E61.3 Manganese deficiency
0.180 0.819 0.000
E61.0 Copper deficiency
0.180 0.819 0.000
E51.2 Wernicke's encephalopathy
0.180 0.820 0.000
E53.1 Pyridoxine deficiency
0.179 0.821 0.000
E53.0 Riboflavin deficiency
0.179 0.821 0.000
E03.8 Other specified hypothyroidism
0.178 0.821 0.000
E27.8 Other specified disorders of adrenal gland
0.174 0.824 0.002
E53.8 Deficiency of other specified B group vitamins
0.173 0.827 0.000
E11 Non-insulin-dependent diabetes mellitus
0.169 0.831 0.000
E53.9 Vitamin B deficiency, unspecified
0.151 0.848 0.000
E55.0 Rickets, active
0.148 0.852 0.000
E61.2 Magnesium deficiency
0.146 0.854 0.000
E67.8 Other specified hyperalimentation
0.137 0.862 0.000
E67.3 Hypervitaminosis D
0.137 0.862 0.000
E67.2 Megavitamin-B6 syndrome
0.137 0.862 0.000
E67.1 Hypercarotenaemia
0.137 0.862 0.000
E67.0 Hypervitaminosis A
0.137 0.862 0.000
E11.6 With other specified complications
0.137 0.862 0.000
E11.5 With peripheral circulatory complications
0.135 0.865 0.000
E21.0 Primary hyperparathyroidism
0.130 0.870 0.000
E11.0 With coma
0.129 0.871 0.000
E11.1 With ketoacidosis
0.128 0.872 0.000
E04 Other non-toxic goitre
0.121 0.879 0.000
E11.7 With multiple complications
0.121 0.879 0.000
E65 Localised adiposity
0.118 0.882 0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.000 0.899 0.101
E11.8 With unspecified complications
0.096 0.904 0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene
0.000 0.909 0.091
K40 Inguinal hernia
0.000 0.912 0.088
E04.8 Other specified non-toxic goitre
0.087 0.913 0.000
E11.3 With ophthalmic complications
0.079 0.921 0.000
E06.3 Autoimmune thyroiditis
0.073 0.925 0.002
E11.2 With renal complications
0.074 0.926 0.000
E04.0 Non-toxic diffuse goitre
0.072 0.928 0.000
S02.40 Fracture of malar and maxillary bones (closed)
0.072 0.928 0.000
E55.9 Vitamin D deficiency, unspecified
0.069 0.931 0.000
K40.4 Unilateral or unspecified inguinal hernia, with gangrene
0.000 0.933 0.067
E11.4 With neurological complications
0.065 0.935 0.000
N40 Hyperplasia of prostate
0.000 0.936 0.064
K40.1 Bilateral inguinal hernia, with gangrene
0.000 0.936 0.064
E04.9 Non-toxic goitre, unspecified
0.062 0.938 0.000
S02.4 Fracture of malar and maxillary bones
0.059 0.941 0.000
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene
0.000 0.944 0.056
E04.1 Non-toxic single thyroid nodule
0.051 0.949 0.000
S02 Fracture of skull and facial bones
0.050 0.950 0.000
S02.8 Fractures of other skull and facial bones
0.048 0.952 0.000
S02.80 Fractures of other skull and facial bones (closed)
0.047 0.953 0.000
S02.2 Fracture of nasal bones
0.046 0.954 0.000
I83 Varicose veins of lower extremities
0.000 0.956 0.044
S02.20 Fracture of nasal bones (closed)
0.044 0.956 0.000
K90-K93 Other diseases of the digestive system
0.042 0.957 0.001
S02.41 Fracture of malar and maxillary bones (open)
0.043 0.957 0.000
S02.5 Fracture of tooth
0.042 0.958 0.000
K51.9 Ulcerative colitis, unspecified
0.000 0.959 0.041
S02.7 Multiple fractures involving skull and facial bones
0.039 0.961 0.000
S02.3 Fracture of orbital floor
0.038 0.962 0.000
S02.50 Fracture of tooth (closed)
0.037 0.963 0.000
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene
0.000 0.963 0.036
S02.81 Fractures of other skull and facial bones (open)
0.034 0.966 0.000
S02.21 Fracture of nasal bones (open)
0.033 0.967 0.000
E83.5 Disorders of calcium metabolism
0.000 0.968 0.032
S02.0 Fracture of vault of skull
0.032 0.968 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.030 0.969 0.001
S02.70 Multiple fractures involving skull and facial bones (closed)
0.031 0.969 0.000
S02.51 Fracture of tooth (open)
0.030 0.970 0.000
S02.30 Fracture of orbital floor (closed)
0.030 0.970 0.000
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.971 0.029
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.000 0.971 0.029
S02.9 Fracture of skull and facial bones, part unspecified
0.028 0.972 0.000
S02.71 Multiple fractures involving skull and facial bones (open)
0.028 0.972 0.000
E11.9 Without complications
0.028 0.972 0.000
S02.31 Fracture of orbital floor (open)
0.027 0.972 0.000
S02.1 Fracture of base of skull
0.027 0.973 0.000
S02.6 Fracture of mandible
0.025 0.974 0.000
L40.9 Psoriasis, unspecified
0.024 0.976 0.000
L40 Psoriasis
0.024 0.976 0.000
S02.01 Fracture of vault of skull (open)
0.023 0.977 0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.022 0.978 0.001
K93.1 Megacolon in Chagas' disease
0.022 0.978 0.001
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.022 0.978 0.001
L40.5 Arthropathic psoriasis
0.022 0.978 0.000
L40.0 Psoriasis vulgaris
0.022 0.978 0.000
E66 Obesity
0.021 0.978 0.000
S02.91 Fracture of skull and facial bones, part unspecified (open)
0.020 0.980 0.000
K51 Ulcerative colitis
0.000 0.980 0.020
E70-E90 Metabolic disorders
0.002 0.980 0.018
S02.11 Fracture of base of skull (open)
0.019 0.980 0.000
L40.1 Generalised pustular psoriasis
0.019 0.981 0.000
L40.3 Pustulosis palmaris et plantaris
0.019 0.981 0.000
S02.00 Fracture of vault of skull (closed)
0.019 0.981 0.000
S02.61 Fracture of mandible (open)
0.018 0.981 0.000
K51.2 Ulcerative (chronic) proctitis
0.000 0.982 0.018
L40.4 Guttate psoriasis
0.018 0.982 0.000
L40.2 Acrodermatitis continua
0.017 0.983 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.001 0.983 0.017
L40.8 Other psoriasis
0.017 0.983 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.000 0.983 0.017
L05.9 Pilonidal cyst without abscess
0.000 0.984 0.016
E66.1 Drug-induced obesity
0.016 0.984 0.000
E79 Disorders of purine and pyrimidine metabolism
0.001 0.984 0.014
E80.4 Gilbert's syndrome
0.000 0.984 0.015
E85 Amyloidosis
0.001 0.984 0.015
K51.1 Ulcerative (chronic) ileocolitis
0.000 0.985 0.015
E74 Other disorders of carbohydrate metabolism
0.001 0.985 0.013
E77 Disorders of glycoprotein metabolism
0.001 0.985 0.013
E76 Disorders of glycosaminoglycan metabolism
0.001 0.985 0.013
E72 Other disorders of amino-acid metabolism
0.001 0.985 0.013
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.001 0.985 0.013
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.001 0.985 0.013
E80.6 Other disorders of bilirubin metabolism
0.000 0.986 0.014
E66.2 Extreme obesity with alveolar hypoventilation
0.014 0.986 0.000
E70 Disorders of aromatic amino-acid metabolism
0.001 0.986 0.013
K51.4 Pseudopolyposis of colon
0.000 0.986 0.014
E80.1 Porphyria cutanea tarda
0.000 0.986 0.013
E73 Lactose intolerance
0.001 0.986 0.012
M67.8 Other specified disorders of synovium and tendon
0.014 0.986 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.002 0.987 0.011
E84 Cystic fibrosis
0.002 0.987 0.011
E85.9 Amyloidosis, unspecified
0.000 0.987 0.013
E80.5 Crigler-Najjar syndrome
0.001 0.987 0.012
E80.3 Defects of catalase and peroxydase
0.001 0.987 0.012
E80.0 Hereditary erythropoietic porphyria
0.001 0.987 0.012
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.001 0.987 0.012
K51.0 Ulcerative (chronic) enterocolitis
0.000 0.987 0.013
S02.90 Fracture of skull and facial bones, part unspecified (closed)
0.012 0.987 0.001
T50.9 Other and unspecified drugs, medicaments and biological substances
0.000 0.987 0.012
K51.5 Mucosal proctocolitis
0.000 0.988 0.012
E80.7 Disorder of bilirubin metabolism, unspecified
0.001 0.988 0.011
L05 Pilonidal cyst
0.000 0.988 0.012
E85.3 Secondary systemic amyloidosis
0.001 0.988 0.011
L05.0 Pilonidal cyst with abscess
0.000 0.988 0.012
E80.2 Other porphyria
0.001 0.988 0.011
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.001 0.988 0.010
E79.8 Other disorders of purine and pyrimidine metabolism
0.001 0.988 0.010
E79.1 Lesch-Nyhan syndrome
0.001 0.988 0.010
E85.8 Other amyloidosis
0.001 0.989 0.011
E85.2 Heredofamilial amyloidosis, unspecified
0.001 0.989 0.011
E85.1 Neuropathic heredofamilial amyloidosis
0.001 0.989 0.011
E85.0 Nonneuropathic heredofamilial amyloidosis
0.001 0.989 0.011
E74.3 Other disorders of intestinal carbohydrate absorption
0.001 0.989 0.010
E74.9 Disorder of carbohydrate metabolism, unspecified
0.001 0.989 0.010
E74.8 Other specified disorders of carbohydrate metabolism
0.001 0.989 0.010
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.001 0.989 0.010
E74.2 Disorders of galactose metabolism
0.001 0.989 0.010
E74.1 Disorders of fructose metabolism
0.001 0.989 0.010
E74.0 Glycogen storage disease
0.001 0.989 0.010
E71.3 Disorders of fatty-acid metabolism
0.001 0.989 0.009
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.001 0.989 0.009
E71.1 Other disorders of branched-chain amino-acid metabolism
0.001 0.989 0.009
E71.0 Maple-syrup-urine disease
0.001 0.989 0.009
E72.9 Disorder of amino-acid metabolism, unspecified
0.001 0.989 0.009
E72.8 Other specified disorders of amino-acid metabolism
0.001 0.989 0.009
E72.5 Disorders of glycine metabolism
0.001 0.989 0.009
E72.4 Disorders of ornithine metabolism
0.001 0.989 0.009
E72.3 Disorders of lysine and hydroxylysine metabolism
0.001 0.989 0.009
E72.2 Disorders of urea cycle metabolism
0.001 0.989 0.009
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.001 0.989 0.009
E72.0 Disorders of amino-acid transport
0.001 0.989 0.009
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.001 0.989 0.009
E76.8 Other disorders of glucosaminoglycan metabolism
0.001 0.989 0.009
E76.3 Mucopolysaccharidosis, unspecified
0.001 0.989 0.009
E76.2 Other mucopolysaccharidoses
0.001 0.989 0.009
E76.1 Mucopolysaccharidosis, type II
0.001 0.989 0.009
E76.0 Mucopolysaccharidosis, type I
0.001 0.989 0.009
E77.9 Disorder of glycoprotein metabolism, unspecified
0.001 0.989 0.009
E77.8 Other disorders of glycoprotein metabolism
0.001 0.989 0.009
E77.1 Defects in glycoprotein degradation
0.001 0.989 0.009
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.001 0.989 0.009
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.001 0.990 0.009
E70.8 Other disorders of aromatic amino-acid metabolism
0.001 0.990 0.009
E70.2 Disorders of tyrosine metabolism
0.001 0.990 0.009
E70.1 Other hyperphenylalaninaemias
0.001 0.990 0.009
E70.0 Classical phenylketonuria
0.001 0.990 0.009
E70.3 Albinism
0.001 0.990 0.009
E85.4 Organ-limited amyloidosis
0.001 0.990 0.009
E73.8 Other lactose intolerance
0.001 0.990 0.009
E73.1 Secondary lactase deficiency
0.001 0.990 0.009
E73.0 Congenital lactase deficiency
0.001 0.990 0.009
S02.10 Fracture of base of skull (closed)
0.010 0.990 0.000
E75.6 Lipid storage disorder, unspecified
0.001 0.990 0.008
E75.4 Neuronal ceroid lipofuscinosis
0.001 0.990 0.008
E75.3 Sphingolipidosis, unspecified
0.001 0.990 0.008
E75.1 Other gangliosidosis
0.001 0.990 0.008
E75.0 GM2 gangliosidosis
0.001 0.990 0.008
E84.8 Cystic fibrosis with other manifestations
0.001 0.990 0.008
E84.1 Cystic fibrosis with intestinal manifestations
0.001 0.990 0.008
E84.0 Cystic fibrosis with pulmonary manifestations
0.001 0.990 0.008
E75.2 Other sphingolipidosis
0.001 0.990 0.008
I73.9 Peripheral vascular disease, unspecified
0.010 0.990 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.990 0.009
M75.0 Adhesive capsulitis of shoulder
0.010 0.990 0.000
E66.0 Obesity due to excess calories
0.009 0.991 0.001
E73.9 Lactose intolerance, unspecified
0.001 0.991 0.008
E04.2 Non-toxic multinodular goitre
0.009 0.991 0.000
E75.5 Other lipid storage disorders
0.002 0.992 0.007
M67 Other disorders of synovium and tendon
0.008 0.992 0.000
E84.9 Cystic fibrosis, unspecified
0.002 0.992 0.007
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.992 0.008
S02.60 Fracture of mandible (closed)
0.008 0.992 0.000
E88 Other metabolic disorders
0.001 0.992 0.007
I83.1 Varicose veins of lower extremities with inflammation
0.000 0.992 0.008
S22.20 Fracture of sternum (closed)
0.008 0.992 0.000
E89.4 Postprocedural ovarian failure
0.000 0.993 0.007
E89.2 Postprocedural hypoparathyroidism
0.000 0.993 0.007
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.000 0.993 0.007
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.993 0.007
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.993 0.007
E89.5 Postprocedural testicular hypofunction
0.000 0.993 0.007
E89.1 Postprocedural hypoinsulinaemia
0.000 0.993 0.007
N50.8 Other specified disorders of male genital organs
0.007 0.993 0.000
M67.4 Ganglion
0.007 0.993 0.000
L40-L45 Papulosquamous disorders
0.007 0.993 0.000
M67.2 Synovial hypertrophy, not elsewhere classified
0.007 0.993 0.000
K51.8 Other ulcerative colitis
0.000 0.993 0.007
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.993 0.007
O69.2 Labour and delivery complicated by other cord entanglement
0.000 0.993 0.007
M67.0 Short Achilles tendon (acquired)
0.007 0.993 0.000
E89.3 Postprocedural hypopituitarism
0.000 0.993 0.006
S22.2 Fracture of sternum
0.006 0.994 0.000
M67.9 Disorder of synovium and tendon, unspecified
0.006 0.994 0.000
M67.3 Transient synovitis
0.006 0.994 0.000
T50.8 Diagnostic agents
0.000 0.994 0.006
E88.3 Tumour lysis syndrome
0.001 0.994 0.005
M67.47 Ganglion, ankle and foot
0.006 0.994 0.000
E88.8 Other specified metabolic disorders
0.001 0.994 0.005
L44 Other papulosquamous disorders
0.006 0.994 0.000
R30-R39 Symptoms and signs involving the urinary system
0.000 0.994 0.006
E88.1 Lipodystrophy, not elsewhere classified
0.001 0.994 0.005
M67.43 Ganglion, wrist
0.005 0.995 0.000
T50.7 Analeptics and opioid receptor antagonists
0.000 0.995 0.005
T50.5 Appetite depressants
0.000 0.995 0.005
T50.3 Electrolytic, caloric and water-balance agents
0.000 0.995 0.005
T50.1 Loop [high-ceiling] diuretics
0.000 0.995 0.005
T50.0 Mineralocorticoids and their antagonists
0.000 0.995 0.005
S22 Fracture of rib(s), sternum and thoracic spine
0.005 0.995 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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