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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs115303880
log Bayes Factor = 77.0089
Chromosome 6   position 32,358,459  (GRCh37) Explore rs115303880 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
C44.3 Skin of other and unspecified parts of face
1.000 0.000 0.000
E10.9 Without complications
0.000 0.000 1.000
K51.9 Ulcerative colitis, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
C44 Other malignant neoplasms of skin
1.000 0.000 0.000
K51 Ulcerative colitis
1.000 0.000 0.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
C44.7 Skin of lower limb, including hip
0.999 0.001 0.000
K50-K52 Noninfective enteritis and colitis
0.999 0.001 0.000
K50 Crohn's disease [regional enteritis]
0.999 0.001 0.000
K50.1 Crohn's disease of large intestine
0.999 0.001 0.000
D86 Sarcoidosis
0.000 0.004 0.996
D86.9 Sarcoidosis, unspecified
0.000 0.004 0.996
C44.4 Skin of scalp and neck
0.996 0.004 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.995 0.005 0.000
Z93.2 Ileostomy status
0.993 0.007 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.993 0.007 0.000
E10.1 With ketoacidosis
0.000 0.010 0.990
E10.3 With ophthalmic complications
0.000 0.010 0.990
K51.4 Pseudopolyposis of colon
0.990 0.010 0.000
D86.0 Sarcoidosis of lung
0.000 0.012 0.988
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.976 0.024 0.000
C44.2 Skin of ear and external auricular canal
0.975 0.025 0.000
C44.5 Skin of trunk
0.975 0.025 0.000
C44.6 Skin of upper limb, including shoulder
0.965 0.035 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.962 0.038 0.000
K51.8 Other ulcerative colitis
0.959 0.041 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.959 0.041 0.000
C83.3 Large cell (diffuse)
0.957 0.043 0.000
K51.2 Ulcerative (chronic) proctitis
0.953 0.047 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.947 0.053 0.000
C44.0 Skin of lip
0.936 0.064 0.000
K50.9 Crohn's disease, unspecified
0.926 0.074 0.000
E10-E14 Diabetes mellitus
0.000 0.080 0.920
D86.8 Sarcoidosis of other and combined sites
0.000 0.081 0.919
D51 Vitamin B12 deficiency anaemia
0.000 0.084 0.916
D50-D53 Nutritional anaemias
0.000 0.084 0.916
C82.0 Small cleaved cell, follicular
0.913 0.087 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.088 0.912
D80-D89 Certain disorders involving the immune mechanism
0.000 0.097 0.902
D50 Iron deficiency anaemia
0.000 0.101 0.899
D86.1 Sarcoidosis of lymph nodes
0.000 0.101 0.899
D50.9 Iron deficiency anaemia, unspecified
0.000 0.102 0.898
E16.2 Hypoglycaemia, unspecified
0.000 0.104 0.896
E16 Other disorders of pancreatic internal secretion
0.000 0.105 0.895
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.108 0.892
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.110 0.890
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.112 0.888
E20-E35 Disorders of other endocrine glands
0.000 0.149 0.851
K52 Other non-infective gastro-enteritis and colitis
0.848 0.152 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.155 0.845
E27 Other disorders of adrenal gland
0.000 0.158 0.842
E27.1 Primary adrenocortical insufficiency
0.000 0.162 0.838
E10.8 With unspecified complications
0.000 0.164 0.836
K51.5 Mucosal proctocolitis
0.836 0.164 0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.832 0.168 0.000
C82.3 Follicular lymphoma grade IIIa
0.799 0.201 0.000
K90 Intestinal malabsorption
0.000 0.222 0.778
C44.1 Skin of eyelid, including canthus
0.774 0.226 0.000
E10.0 With coma
0.000 0.226 0.774
E10.4 With neurological complications
0.000 0.227 0.773
C44.9 Malignant neoplasm of skin, unspecified
0.764 0.236 0.000
C83.1 Small cleaved cell (diffuse)
0.759 0.241 0.000
E22 Hyperfunction of pituitary gland
0.000 0.243 0.757
E10.6 With other specified complications
0.000 0.246 0.754
C85.1 B-cell lymphoma, unspecified
0.753 0.247 0.000
K52.1 Toxic gastro-enteritis and colitis
0.750 0.250 0.000
K52.8 Other specified non-infective gastro-enteritis and colitis
0.747 0.253 0.000
K50.8 Other Crohn's disease
0.740 0.260 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.731 0.269 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.725 0.275 0.000
C81 Hodgkin's disease
0.725 0.275 0.000
E16.1 Other hypoglycaemia
0.000 0.278 0.722
D52 Folate deficiency anaemia
0.000 0.281 0.719
C44.8 Overlapping lesion of skin
0.717 0.283 0.000
E10.7 With multiple complications
0.000 0.283 0.717
C82.2 Large cell, follicular
0.715 0.285 0.000
E10.2 With renal complications
0.000 0.286 0.714
D86.3 Sarcoidosis of skin
0.000 0.286 0.714
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.286 0.714
C82.6 Cutaneous follicle centre lymphoma
0.712 0.288 0.000
C82.5 Diffuse follicle centre lymphoma
0.712 0.288 0.000
C82.4 Follicular lymphoma grade IIIb
0.712 0.288 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.708 0.292 0.000
K52.3 Indeterminate colitis
0.704 0.296 0.000
E14 Unspecified diabetes mellitus
0.000 0.298 0.702
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.700 0.300 0.000
C94 Other leukaemias of specified cell type
0.700 0.300 0.000
C93 Monocytic leukaemia
0.700 0.300 0.000
C86 Other specified types of T/NK-cell lymphoma
0.700 0.300 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.303 0.697
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.304 0.696
C84 Peripheral and cutaneous T-cell lymphomas
0.695 0.305 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.309 0.691
C83.6 Undifferentiated (diffuse)
0.690 0.310 0.000
C83.5 Lymphoblastic (diffuse)
0.690 0.310 0.000
C83.4 Immunoblastic (diffuse)
0.690 0.310 0.000
C83.2 Mixed small and large cell (diffuse)
0.690 0.310 0.000
C95 Leukaemia of unspecified cell type
0.689 0.311 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.687 0.313 0.000
C85.0 Lymphosarcoma
0.687 0.313 0.000
E13 Other specified diabetes mellitus
0.000 0.313 0.687
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.329 0.671
C82.1 Mixed small cleaved and large cell, follicular
0.670 0.330 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.334 0.666
E24 Cushing's syndrome
0.000 0.336 0.664
E27.2 Addisonian crisis
0.000 0.337 0.663
C83.7 Burkitt's tumour
0.662 0.338 0.000
E12 Malnutrition-related diabetes mellitus
0.000 0.340 0.660
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.343 0.657
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.343 0.657
D51.2 Transcobalamin II deficiency
0.000 0.343 0.657
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.343 0.657
D82 Immunodeficiency associated with other major defects
0.000 0.353 0.647
D81 Combined immunodeficiencies
0.000 0.353 0.647
E10.5 With peripheral circulatory complications
0.000 0.354 0.646
D50.1 Sideropenic dysphagia
0.000 0.355 0.645
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.358 0.641
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.358 0.641
E16.4 Abnormal secretion of gastrin
0.000 0.358 0.641
E16.3 Increased secretion of glucagon
0.000 0.358 0.641
K51.1 Ulcerative (chronic) ileocolitis
0.640 0.360 0.000
E15 Nondiabetic hypoglycaemic coma
0.000 0.361 0.639
D53 Other nutritional anaemias
0.000 0.365 0.635
K90.9 Intestinal malabsorption, unspecified
0.000 0.374 0.626
C90 Multiple myeloma and malignant plasma cell neoplasms
0.626 0.374 0.000
C88 Malignant immunoproliferative diseases
0.620 0.380 0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.619 0.381 0.000
E20 Hypoparathyroidism
0.000 0.385 0.615
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.390 0.610
E32 Diseases of thymus
0.000 0.390 0.610
E31 Polyglandular dysfunction
0.000 0.390 0.610
E30 Disorders of puberty, not elsewhere classified
0.000 0.390 0.610
E25 Adrenogenital disorders
0.000 0.390 0.610
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.395 0.605
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.604 0.396 0.000
E27.5 Adrenomedullary hyperfunction
0.000 0.396 0.604
E27.0 Other adrenocortical overactivity
0.000 0.396 0.604
D55-D59 Haemolytic anaemias
0.000 0.405 0.595
E21.0 Primary hyperparathyroidism
0.000 0.408 0.592
C81.1 Nodular sclerosis
0.591 0.409 0.000
K90.8 Other intestinal malabsorption
0.000 0.411 0.589
E14.9 Without complications
0.000 0.415 0.585
C85.7 Other specified types of non-Hodgkin's lymphoma
0.579 0.421 0.000
E22.0 Acromegaly and pituitary gigantism
0.000 0.422 0.578
D52.9 Folate deficiency anaemia, unspecified
0.000 0.422 0.578
E40-E46 Malnutrition
0.000 0.424 0.576
D83 Common variable immunodeficiency
0.000 0.433 0.566
E34 Other endocrine disorders
0.000 0.438 0.561
E27.8 Other specified disorders of adrenal gland
0.000 0.440 0.560
K90.3 Pancreatic steatorrhoea
0.000 0.442 0.558
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.442 0.558
K90.1 Tropical sprue
0.000 0.442 0.558
E22.1 Hyperprolactinaemia
0.000 0.443 0.557
D80 Immunodeficiency with predominantly antibody defects
0.000 0.443 0.556
C81.2 Mixed cellularity
0.552 0.448 0.000
C81.0 Lymphocytic predominance
0.547 0.453 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.457 0.543
E22.8 Other hyperfunction of pituitary gland
0.000 0.457 0.543
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.463 0.537
C95.0 Acute leukaemia of unspecified cell type
0.536 0.464 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.535 0.465 0.000
E24.9 Cushing's syndrome, unspecified
0.000 0.471 0.529
E14.3 With ophthalmic complications
0.000 0.471 0.529
D84 Other immunodeficiencies
0.000 0.476 0.524
C81.7 Other Hodgkin's disease
0.520 0.480 0.000
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.520 0.480 0.000
C81.3 Lymphocytic depletion
0.520 0.480 0.000
E13.9 Without complications
0.000 0.481 0.519
D52.8 Other folate deficiency anaemias
0.000 0.484 0.516
D52.1 Drug-induced folate deficiency anaemia
0.000 0.484 0.516
D52.0 Dietary folate deficiency anaemia
0.000 0.484 0.516
E29 Testicular dysfunction
0.000 0.487 0.513
C84.0 Mycosis fungoides
0.512 0.488 0.000
E14.8 With unspecified complications
0.000 0.496 0.504
E14.7 With multiple complications
0.000 0.496 0.504
E14.2 Withrenal complications
0.000 0.496 0.504
E14.1 With ketoacidosis
0.000 0.496 0.504
E14.0 With coma
0.000 0.496 0.504
C86.6 Primary cutaneous CD30-positive T-cell proliferations
0.502 0.498 0.000
C86.5 Angioimmunoblastic T-cell lymphoma
0.502 0.498 0.000
C86.4 Blastic NK-cell lymphoma
0.502 0.498 0.000
C86.3 Subcutaneous panniculitis-like T-cell lymphoma
0.502 0.498 0.000
C86.2 Enteropathy-type (intestinal) T-cell lymphoma
0.502 0.498 0.000
C86.1 Hepatosplenic T-cell lymphoma
0.502 0.498 0.000
C86.0 Extranodal NK/T-cell lymphoma, nasal type
0.502 0.498 0.000
C93.9 Monocytic leukaemia, unspecified
0.502 0.498 0.000
C93.7 Other monocytic leukaemia
0.502 0.498 0.000
C93.3 Juvenile myelomonocytic leukaemia
0.502 0.498 0.000
C93.2 Subacute monocytic leukaemia
0.502 0.498 0.000
C93.1 Chronic monocytic leukaemia
0.502 0.498 0.000
C93.0 Acute monocytic leukaemia
0.502 0.498 0.000
C94.7 Other specified leukaemias
0.502 0.498 0.000
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified
0.502 0.498 0.000
C94.5 Acute myelofibrosis
0.502 0.498 0.000
C94.4 Acute panmyelosis
0.502 0.498 0.000
C94.3 Mast cell leukaemia
0.502 0.498 0.000
C94.2 Acute megakaryoblastic leukaemia
0.502 0.498 0.000
C94.1 Chronic erythraemia
0.502 0.498 0.000
C94.0 Acute erythraemia and erythroleukaemia
0.502 0.498 0.000
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified
0.502 0.498 0.000
C96.8 Histiocytic sarcoma
0.502 0.498 0.000
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.502 0.498 0.000
C96.6 Unifocal Langerhans-cell histiocytosis
0.502 0.498 0.000
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis
0.502 0.498 0.000
C96.4 Sarcoma of dendritic cells (accessory cells)
0.502 0.498 0.000
C96.3 True histiocytic lymphoma
0.502 0.498 0.000
C96.2 Malignant mast cell tumour
0.502 0.498 0.000
C96.1 Malignant histiocytosis
0.502 0.498 0.000
C96.0 Letterer-Siwe disease
0.502 0.498 0.000
C84.4 Peripheral T-cell lymphoma
0.501 0.499 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.500 0.500
E21.4 Other specified disorders of parathyroid gland
0.000 0.500 0.500
E21.2 Other hyperparathyroidism
0.000 0.500 0.500
C84.9 Mature T/NK-cell lymphoma, unspecified
0.498 0.502 0.000
C84.8 Cutaneous T-cell lymphoma, unspecified
0.498 0.502 0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.498 0.502 0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.498 0.502 0.000
C84.3 Lymphoepithelioid lymphoma
0.498 0.502 0.000
C84.2 T-zone lymphoma
0.498 0.502 0.000
C84.1 Sezary's diease
0.498 0.502 0.000
C95.7 Other leukaemia of unspecified cell type
0.494 0.506 0.000
C95.2 Subacute leukaemia of unspecified cell type
0.494 0.506 0.000
C95.1 Chronic leukaemia of unspecified cell type
0.494 0.506 0.000
E13.8 With unspecified complications
0.000 0.508 0.492
E13.7 With multiple complications
0.000 0.508 0.492
E13.6 With other specified complications
0.000 0.508 0.492
E13.5 With peripheral circulatory complications
0.000 0.508 0.492
E13.4 With neurological complications
0.000 0.508 0.492
E13.3 With ophthalmic complications
0.000 0.508 0.492
E13.2 With renal complications
0.000 0.508 0.492
E13.1 With ketoacidosis
0.000 0.508 0.492
E13.0 With coma
0.000 0.508 0.492
D59 Acquired haemolytic anaemia
0.000 0.509 0.491
E14.6 With other specified complications
0.000 0.513 0.487
E14.5 With peripheral circulatory complications
0.000 0.517 0.483
C84.5 Other and unspecified T-cell lymphomas
0.476 0.524 0.000
E24.8 Other Cushing's syndrome
0.000 0.524 0.476
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.524 0.476
E24.3 Ectopic ACTH syndrome
0.000 0.524 0.476
E24.2 Drug-induced Cushing's syndrome
0.000 0.524 0.476
E24.1 Nelson's syndrome
0.000 0.524 0.476
E24.0 Pituitary-dependent Cushing's disease
0.000 0.524 0.476
E12.9 Without complications
0.000 0.527 0.473
E12.8 With unspecified complications
0.000 0.527 0.473
E12.7 With multiple complications
0.000 0.527 0.473
E12.6 With other specified complications
0.000 0.527 0.473
E12.5 With peripheral circulatory complications
0.000 0.527 0.473
E12.4 With neurological complications
0.000 0.527 0.473
E12.3 With ophthalmic complications
0.000 0.527 0.473
E12.2 With renal complications
0.000 0.527 0.473
E12.1 With ketoacidosis
0.000 0.527 0.473
E12.0 With coma
0.000 0.527 0.473
E34.0 Carcinoid syndrome
0.000 0.532 0.468
E65-E68 Obesity and other hyperalimentation
0.000 0.535 0.465
D81.9 Combined immunodeficiency, unspecified
0.000 0.536 0.464
D81.8 Other combined immunodeficiencies
0.000 0.536 0.464
D81.7 Major histocompatibility complex class II deficiency
0.000 0.536 0.464
D81.6 Major histocompatibility complex class I deficiency
0.000 0.536 0.464
D81.5 Purine nucleoside phosphorylase [PNP] deficiency
0.000 0.536 0.464
D81.4 Nezelof's syndrome
0.000 0.536 0.464
D81.3 Adenosine deaminase [ADA] deficiency
0.000 0.536 0.464
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
0.000 0.536 0.464
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
0.000 0.536 0.464
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis
0.000 0.536 0.464
D82.9 Immunodeficiency associated with major defect, unspecified
0.000 0.536 0.464
D82.8 Immunodeficiency associated with other specified major defects
0.000 0.536 0.464
D82.4 Hyperimmunoglobulin E [IgE] syndrome
0.000 0.536 0.464
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus
0.000 0.536 0.464
D82.2 Immunodeficiency with short-limbed stature
0.000 0.536 0.464
D82.1 Di George's syndrome
0.000 0.536 0.464
D82.0 Wiskott-Aldrich syndrome
0.000 0.536 0.464
E00-E07 Disorders of thyroid gland
0.000 0.538 0.462
K52.0 Gastro-enteritis and colitis due to radiation
0.461 0.538 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.543 0.457
D53.8 Other specified nutritional anaemias
0.000 0.544 0.455
D53.2 Scorbutic anaemia
0.000 0.544 0.455
D53.1 Other megaloblastic anaemias, not elsewhere classified
0.000 0.544 0.455
D53.0 Protein deficiency anaemia
0.000 0.544 0.455
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.546 0.454
E50-E64 Other nutritional deficiencies
0.000 0.549 0.450
C91 Lymphoid leukaemia
0.449 0.550 0.001
E14.4 With neurological complications
0.000 0.550 0.449
C90.3 Solitary plasmacytoma
0.449 0.551 0.000
C90.1 Plasma cell leukaemia
0.449 0.551 0.000
E20.9 Hypoparathyroidism, unspecified
0.000 0.553 0.446
C88.9 Malignant immunoproliferative disease, unspecified
0.445 0.555 0.000
C88.7 Other malignant immunoproliferative diseases
0.445 0.555 0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.445 0.555 0.000
C88.3 Immunoproliferative small intestinal disease
0.445 0.555 0.000
C88.2 Gamma heavy chain disease
0.445 0.555 0.000
C88.1 Alpha heavy chain disease
0.445 0.555 0.000
E21.3 Hyperparathyroidism, unspecified
0.000 0.557 0.443
E20.8 Other hypoparathyroidism
0.000 0.559 0.441
E20.1 Pseudohypoparathyroidism
0.000 0.559 0.441
E20.0 Idiopathic hypoparathyroidism
0.000 0.559 0.441
C90.0 Multiple myeloma
0.440 0.560 0.000
E25.9 Adrenogenital disorder, unspecified
0.000 0.562 0.437
E25.8 Other adrenogenital disorders
0.000 0.562 0.437
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.562 0.437
E30.9 Disorder of puberty, unspecified
0.000 0.562 0.437
E30.8 Other disorders of puberty
0.000 0.562 0.437
E30.1 Precocious puberty
0.000 0.562 0.437
E30.0 Delayed puberty
0.000 0.562 0.437
E31.9 Polyglandular dysfunction, unspecified
0.000 0.562 0.437
E31.8 Other polyglandular dysfunction
0.000 0.562 0.437
E31.1 Polyglandular hyperfunction
0.000 0.562 0.437
E31.0 Autoimmune polyglandular failure
0.000 0.562 0.437
E32.9 Disease of thymus, unspecified
0.000 0.562 0.437
E32.8 Other diseases of thymus
0.000 0.562 0.437
E32.1 Abscess of thymus
0.000 0.562 0.437
E32.0 Persistent hyperplasia of thymus
0.000 0.562 0.437
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.562 0.437
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.562 0.437
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.562 0.437
C83.0 Small cell (diffuse)
0.434 0.566 0.001
D53.9 Nutritional anaemia, unspecified
0.000 0.566 0.434
C95.9 Leukaemia, unspecified
0.429 0.571 0.000
D57 Sickle-cell disorders
0.000 0.573 0.427
D55 Anaemia due to enzyme disorders
0.000 0.573 0.427
C92 Myeloid leukaemia
0.423 0.577 0.000
D59.1 Other autoimmune haemolytic anaemias
0.000 0.583 0.417
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.587 0.413
E45 Retarded development following protein-energy malnutrition
0.000 0.587 0.413
E43 Unspecified severe protein-energy malnutrition
0.000 0.587 0.413
E42 Marasmic kwashiorkor
0.000 0.587 0.413
E41 Nutritional marasmus
0.000 0.587 0.413
E40 Kwashiorkor
0.000 0.587 0.413
E03 Other hypothyroidism
0.000 0.590 0.410
D83.8 Other common variable immunodeficiencies
0.000 0.594 0.406
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells
0.000 0.594 0.406
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
0.000 0.594 0.406
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
0.000 0.594 0.406
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.594 0.406
E34.5 Androgen resistance syndrome
0.000 0.597 0.403
E34.4 Constitutional tall stature
0.000 0.597 0.403
E34.3 Short stature, not elsewhere classified
0.000 0.597 0.403
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.597 0.403
E34.1 Other hypersecretion of intestinal hormones
0.000 0.597 0.403
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.000 0.601 0.399
D80.8 Other immunodeficiencies with predominantly antibody defects
0.000 0.601 0.399
D80.7 Transient hypogammaglobulinaemia of infancy
0.000 0.601 0.399
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.000 0.601 0.399
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.000 0.601 0.399
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.000 0.601 0.399
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.000 0.601 0.399
D80.0 Hereditary hypogammaglobulinaemia
0.000 0.601 0.399
E28 Ovarian dysfunction
0.000 0.607 0.393
C90.2 Plasmacytoma, extramedullary
0.386 0.614 0.000
C91.5 Adult T-cell leukaemia
0.384 0.616 0.001
E03.9 Hypothyroidism, unspecified
0.000 0.624 0.376
D84.8 Other specified immunodeficiencies
0.000 0.624 0.375
D84.1 Defects in the complement system
0.000 0.624 0.375
D84.0 Lymphocyte function antigen-1 [LFA-1] defect
0.000 0.624 0.375
D80.1 Nonfamilial hypogammaglobulinaemia
0.000 0.629 0.371
J45 Asthma
0.000 0.629 0.371
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.629 0.371
E53 Deficiency of other B group vitamins
0.000 0.631 0.369
E29.9 Testicular dysfunction, unspecified
0.000 0.632 0.368
E29.8 Other testicular dysfunction
0.000 0.632 0.368
E29.0 Testicular hyperfunction
0.000 0.632 0.368
C88.0 Waldenstrom's macroglobulinaemia
0.365 0.635 0.000
D56 Thalassaemia
0.000 0.635 0.365
Chapter II Neoplasms
0.365 0.635 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.362 0.638 0.000
E26 Hyperaldosteronism
0.002 0.638 0.360
C91.9 Lymphoid leukaemia, unspecified
0.359 0.640 0.001
C73 Malignant neoplasm of thyroid gland
0.360 0.640 0.000
E34.8 Other specified endocrine disorders
0.000 0.642 0.358
E27.9 Disorder of adrenal gland, unspecified
0.001 0.642 0.357
D59.8 Other acquired haemolytic anaemias
0.000 0.648 0.352
D59.6 Haemoglobinuria due to haemolysis from other external causes
0.000 0.648 0.352
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]
0.000 0.648 0.352
D59.4 Other nonautoimmune haemolytic anaemias
0.000 0.648 0.352
D59.3 Haemolytic-uraemic syndrome
0.000 0.648 0.352
D59.2 Drug-induced nonautoimmune haemolytic anaemia
0.000 0.648 0.352
D59.0 Drug-induced autoimmune haemolytic anaemia
0.000 0.648 0.352
E46 Unspecified protein-energy malnutrition
0.000 0.649 0.351
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.650 0.350
D59.9 Acquired haemolytic anaemia, unspecified
0.000 0.651 0.349
C81.9 Hodgkin's disease, unspecified
0.349 0.651 0.000
D58 Other hereditary haemolytic anaemias
0.000 0.652 0.347
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.000 0.654 0.346
E67 Other hyperalimentation
0.000 0.666 0.333
E68 Sequelae of hyperalimentation
0.000 0.666 0.333
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.669 0.331
E00 Congenital iodine-deficiency syndrome
0.000 0.669 0.331
D83.9 Common variable immunodeficiency, unspecified
0.001 0.674 0.325
D89.9 Disorder involving the immune mechanism, unspecified
0.000 0.674 0.325
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.000 0.674 0.325
D89.3 Immune reconstitution syndrome
0.000 0.674 0.325
D89.0 Polyclonal hypergammaglobulinaemia
0.000 0.674 0.325
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.677 0.323
E63 Other nutritional deficiencies
0.000 0.677 0.323
E56 Other vitamin deficiencies
0.000 0.677 0.323
E50 Vitamin A deficiency
0.000 0.677 0.323
E60 Dietary zinc deficiency
0.000 0.677 0.323
E59 Dietary selenium deficiency
0.000 0.677 0.323
E54 Ascorbic acid deficiency
0.000 0.677 0.323
E52 Niacin deficiency [pellagra]
0.000 0.677 0.323
C91.8 Mature B-cell leukaemia Burkitt-type
0.322 0.677 0.001
C91.7 Other lymphoid leukaemia
0.322 0.677 0.001
C91.6 Prolymphocytic leukaemia of T-cell type
0.322 0.677 0.001
C91.3 Prolymphocytic leukaemia
0.322 0.677 0.001
C91.2 Subacute lymphocytic leukaemia
0.322 0.677 0.001
E53.8 Deficiency of other specified B group vitamins
0.000 0.688 0.312
D66 Hereditary factor VIII deficiency
0.000 0.688 0.312
E06 Thyroiditis
0.000 0.689 0.311
D55.9 Anaemia due to enzyme disorder, unspecified
0.000 0.694 0.306
D55.8 Other anaemias due to enzyme disorders
0.000 0.694 0.306
D55.3 Anaemia due to disorders of nucleotide metabolism
0.000 0.694 0.306
D55.2 Anaemia due to disorders of glycolytic enzymes
0.000 0.694 0.306
D55.1 Anaemia due to other disorders of glutathione metabolism
0.000 0.694 0.306
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency
0.000 0.694 0.306
D57.8 Other sickle-cell disorders
0.000 0.694 0.306
D57.3 Sickle-cell trait
0.000 0.694 0.306
D57.2 Double heterozygous sickling disorders
0.000 0.694 0.306
D57.1 Sickle-cell anaemia without crisis
0.000 0.694 0.306
D57.0 Sickle-cell anaemia with crisis
0.000 0.694 0.306
C92.9 Myeloid leukaemia, unspecified
0.303 0.696 0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia
0.303 0.696 0.000
C92.7 Other myeloid leukaemia
0.303 0.696 0.000
C92.6 Acute myeloid leukaemia with 11q23-abnormality
0.303 0.696 0.000
C92.5 Acute myelomonocytic leukaemia
0.303 0.696 0.000
C92.4 Acute promyelocytic leukaemia
0.303 0.696 0.000
C92.3 Myeloid sarcoma
0.303 0.696 0.000
C92.2 Subacute myeloid leukaemia
0.303 0.696 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.697 0.303
E51 Thiamine deficiency
0.000 0.701 0.299
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.299 0.701 0.000
E58 Dietary calcium deficiency
0.000 0.702 0.298
E44.1 Mild protein-energy malnutrition
0.000 0.704 0.296
E44.0 Moderate protein-energy malnutrition
0.000 0.704 0.296
E66 Obesity
0.000 0.704 0.296
E03.5 Myxoedema coma
0.000 0.706 0.294
E03.4 Atrophy of thyroid (acquired)
0.000 0.706 0.294
E03.3 Postinfectious hypothyroidism
0.000 0.706 0.294
E03.1 Congenital hypothyroidism without goitre
0.000 0.706 0.294
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.706 0.294
M06.9 Rheumatoid arthritis, unspecified
0.293 0.707 0.000
D67 Hereditary factor IX deficiency
0.000 0.709 0.291
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.000 0.709 0.291
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.709 0.291
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.713 0.287
M06 Other rheumatoid arthritis
0.286 0.714 0.000
E34.9 Endocrine disorder, unspecified
0.001 0.714 0.285
M06.0 Seronegative rheumatoid arthritis
0.286 0.714 0.000
D89.1 Cryoglobulinaemia
0.000 0.716 0.284
C74 Malignant neoplasm of adrenal gland
0.282 0.717 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.283 0.717 0.000
E28.9 Ovarian dysfunction, unspecified
0.000 0.718 0.282
E28.8 Other ovarian dysfunction
0.000 0.718 0.282
E28.1 Androgen excess
0.000 0.718 0.282
E28.0 Oestrogen excess
0.000 0.718 0.282
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.281 0.719 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.279 0.721 0.000
E03.8 Other specified hypothyroidism
0.000 0.724 0.276
D50.8 Other iron deficiency anaemias
0.000 0.726 0.274
C02 Malignant neoplasm of other and unspecified parts of tongue
0.273 0.727 0.000
E29.1 Testicular hypofunction
0.000 0.730 0.270
E23 Hypofunction and other disorders of pituitary gland
0.001 0.730 0.269
E11 Non-insulin-dependent diabetes mellitus
0.000 0.732 0.268
D72 Other disorders of white blood cells
0.000 0.732 0.267
E05.8 Other thyrotoxicosis
0.000 0.734 0.266
J45.8 Mixed asthma
0.000 0.734 0.266
J45.1 Nonallergic asthma
0.000 0.734 0.266
E05.5 Thyroid crisis or storm
0.000 0.734 0.266
E05.4 Thyrotoxicosis factitia
0.000 0.734 0.266
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.734 0.266
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.734 0.266
E53.1 Pyridoxine deficiency
0.000 0.735 0.264
E53.0 Riboflavin deficiency
0.000 0.735 0.264
D68 Other coagulation defects
0.000 0.737 0.263
D56.9 Thalassaemia, unspecified
0.000 0.738 0.262
D56.8 Other thalassaemias
0.000 0.738 0.262
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]
0.000 0.738 0.262
D56.2 Delta-beta thalassaemia
0.000 0.738 0.262
D56.0 Alpha thalassaemia
0.000 0.738 0.262
K50.0 Crohn's disease of small intestine
0.261 0.739 0.001
E53.9 Vitamin B deficiency, unspecified
0.000 0.739 0.261
C75 Malignant neoplasm of other endocrine glands and related structures
0.260 0.740 0.000
D72.8 Other specified disorders of white blood cells
0.000 0.740 0.260
E26.8 Other hyperaldosteronism
0.001 0.740 0.258
E26.1 Secondary hyperaldosteronism
0.001 0.740 0.258
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.259 0.741 0.000
D56.3 Thalassaemia trait
0.000 0.742 0.258
C91.0 Acute lymphoblastic leukaemia
0.257 0.742 0.001
C40-C41 Malignant neoplasms of bone and articular cartilage
0.257 0.743 0.000
E61 Deficiency of other nutrient elements
0.000 0.744 0.255
D84.9 Immunodeficiency, unspecified
0.001 0.747 0.252
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.252 0.748 0.000
C06 Malignant neoplasm of other and unspecified parts of mouth
0.251 0.748 0.000
D58.8 Other specified hereditary haemolytic anaemias
0.000 0.750 0.249
D58.2 Other haemoglobinopathies
0.000 0.750 0.249
D58.1 Hereditary elliptocytosis
0.000 0.750 0.249
C02.1 Border of tongue
0.245 0.754 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.243 0.757 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.242 0.758 0.000
J45.0 Predominantly allergic asthma
0.000 0.759 0.241

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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