TreeWAS – Variant ID: rs115484013

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
D64.9 Anaemia, unspecified	1.000	0.000	0.000
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
E05.9 Thyrotoxicosis, unspecified	1.000	0.000	0.000
E05.0 Thyrotoxicosis with diffuse goitre	1.000	0.000	0.000
E10.9 Without complications	1.000	0.000	0.000
E10.3 With ophthalmic complications	1.000	0.000	0.000
K90.0 Coeliac disease	1.000	0.000	0.000
M06.9 Rheumatoid arthritis, unspecified	0.000	0.000	1.000
E05 Thyrotoxicosis [hyperthyroidism]	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
R31 Unspecified haematuria	0.000	0.000	1.000
E20-E35 Disorders of other endocrine glands	1.000	0.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
K90 Intestinal malabsorption	1.000	0.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.000	1.000
E03 Other hypothyroidism	1.000	0.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000	0.000
D64 Other anaemias	1.000	0.000	0.000
E14 Unspecified diabetes mellitus	1.000	0.000	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	1.000	0.000	0.000
E10.1 With ketoacidosis	1.000	0.000	0.000
H36.0 Diabetic retinopathy	1.000	0.000	0.000
D60-D64 Aplastic and other anaemias	1.000	0.000	0.000
M35.0 Sicca syndrome [Sjogren]	1.000	0.000	0.000
D69 Purpura and other haemorrhagic conditions	1.000	0.000	0.000
M06 Other rheumatoid arthritis	0.000	0.000	1.000
I60-I69 Cerebrovascular diseases	1.000	0.000	0.000
Chapter VII Diseases of the eye and adnexa	1.000	0.000	0.000
H30-H36 Disorders of choroid and retina	1.000	0.000	0.000
H36 Retinal disorders in diseases classified elsewhere	1.000	0.000	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.000	0.001	0.999
M05-M14 Inflammatory polyarthropathies	0.001	0.001	0.998
Chapter XI Diseases of the digestive system	0.999	0.001	0.000
M35 Other systemic involvement of connective tissue	0.999	0.001	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.001	0.999
M05 Seropositive rheumatoid arthritis	0.001	0.001	0.999
M20-M25 Other joint disorders	0.999	0.001	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.999	0.001	0.000
M15-M19 Arthrosis	0.999	0.001	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.999	0.001	0.000
D69.6 Thrombocytopenia, unspecified	0.999	0.001	0.000
K70-K77 Diseases of liver	0.999	0.001	0.000
K90-K93 Other diseases of the digestive system	0.998	0.002	0.000
G50-G59 Nerve, nerve root and plexus disorders	0.998	0.002	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.998	0.002	0.000
E16 Other disorders of pancreatic internal secretion	0.998	0.002	0.000
D50-D53 Nutritional anaemias	0.998	0.002	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.997	0.003	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.997	0.003	0.000
E27 Other disorders of adrenal gland	0.997	0.003	0.000
E16.2 Hypoglycaemia, unspecified	0.997	0.003	0.000
E27.1 Primary adrenocortical insufficiency	0.997	0.003	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.996	0.004	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.004	0.996
D50 Iron deficiency anaemia	0.996	0.004	0.000
G56 Mononeuropathies of upper limb	0.996	0.004	0.000
G56.0 Carpal tunnel syndrome	0.996	0.004	0.000
M18 Arthrosis of first carpometacarpal joint	0.995	0.005	0.000
D50.9 Iron deficiency anaemia, unspecified	0.995	0.005	0.000
K90.9 Intestinal malabsorption, unspecified	0.995	0.005	0.000
E14.3 With ophthalmic complications	0.995	0.005	0.000
K75 Other inflammatory liver diseases	0.994	0.006	0.000
Chapter VI Diseases of the nervous system	0.994	0.006	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.992	0.008	0.000
N40 Hyperplasia of prostate	0.000	0.008	0.992
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.991	0.009	0.000
K75.4 Autoimmune hepatitis	0.990	0.010	0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders	0.990	0.010	0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.989	0.010	0.000
H06.2 Dysthyroid exophthalmos	0.988	0.012	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.987	0.013	0.000
C81 Hodgkin's disease	0.985	0.015	0.000
E10.2 With renal complications	0.984	0.016	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.984	0.016	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.983	0.017	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.982	0.018	0.000
C91 Lymphoid leukaemia	0.981	0.019	0.000
H00.1 Chalazion	0.000	0.019	0.981
M17 Gonarthrosis [arthrosis of knee]	0.981	0.019	0.000
M17.1 Other primary gonarthrosis	0.980	0.020	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.021	0.979
E21.0 Primary hyperparathyroidism	0.975	0.025	0.000
E21.3 Hyperparathyroidism, unspecified	0.974	0.026	0.000
E14.9 Without complications	0.974	0.026	0.000
I63 Cerebral infarction	0.971	0.029	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.969	0.031	0.000
D69.4 Other primary thrombocytopenia	0.966	0.034	0.000
K35-K38 Diseases of appendix	0.966	0.034	0.000
E11 Non-insulin-dependent diabetes mellitus	0.965	0.035	0.000
N00-N08 Glomerular diseases	0.964	0.036	0.000
E10.4 With neurological complications	0.962	0.038	0.000
N08 Glomerular disorders in diseases classified elsewhere	0.958	0.042	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.042	0.958
L10-L14 Bullous disorders	0.958	0.042	0.000
N04 Nephrotic syndrome	0.958	0.042	0.000
C91.1 Chronic lymphocytic leukaemia	0.957	0.043	0.000
M18.1 Other primary arthrosis of first carpometacarpal joint	0.957	0.043	0.000
K35 Acute appendicitis	0.956	0.044	0.000
K35.9 Acute appendicitis, unspecified	0.955	0.045	0.000
N05 Unspecified nephritic syndrome	0.955	0.045	0.000
N08.3 Glomerular disorders in diabetes mellitus	0.952	0.048	0.000
H05 Disorders of orbit	0.952	0.048	0.000
D80-D89 Certain disorders involving the immune mechanism	0.951	0.049	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.951	0.049	0.000
K73 Chronic hepatitis, not elsewhere classified	0.951	0.049	0.000
M60-M63 Disorders of muscles	0.950	0.050	0.000
L50-L54 Urticaria and erythema	0.949	0.051	0.000
N04.9 Unspecified	0.945	0.055	0.000
I73 Other peripheral vascular diseases	0.943	0.057	0.000
C85.1 B-cell lymphoma, unspecified	0.943	0.057	0.000
C81.9 Hodgkin's disease, unspecified	0.943	0.057	0.000
Q60-Q64 Congenital malformations of the urinary system	0.942	0.058	0.000
E06 Thyroiditis	0.939	0.061	0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.938	0.062	0.000
L13 Other bullous disorders	0.937	0.063	0.000
M06.3 Rheumatoid nodule	0.000	0.063	0.937
E89.0 Postprocedural hypothyroidism	0.936	0.064	0.000
E11.3 With ophthalmic complications	0.933	0.067	0.000
K74 Fibrosis and cirrhosis of liver	0.933	0.067	0.000
I62 Other nontraumatic intracranial haemorrhage	0.931	0.069	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.929	0.071	0.000
E70-E90 Metabolic disorders	0.928	0.072	0.000
Chapter I Certain infectious and parasitic diseases	0.927	0.073	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.923	0.077	0.000
L13.0 Dermatitis herpetiformis	0.922	0.078	0.000
L80-L99 Other disorders of the skin and subcutaneous tissue	0.921	0.079	0.000
E50-E64 Other nutritional deficiencies	0.919	0.081	0.000
E07 Other disorders of thyroid	0.913	0.087	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.096	0.904
M20.1 Hallux valgus (acquired)	0.000	0.096	0.904
N05.1 Focal and segmental glomerular lesions	0.904	0.096	0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.903	0.097	0.000
M34 Systemic sclerosis	0.901	0.099	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.900	0.100	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.899	0.101	0.000
I77 Other disorders of arteries and arterioles	0.898	0.102	0.000
M32 Systemic lupus erythematosus	0.897	0.103	0.000
G51 Facial nerve disorders	0.893	0.107	0.000
C81.1 Nodular sclerosis	0.892	0.108	0.000
N05.2 Diffuse membranous glomerulonephritis	0.892	0.108	0.000
M06.34 Rheumatoid nodule (Hand)	0.000	0.108	0.892
K73.2 Chronic active hepatitis, not elsewhere classified	0.890	0.110	0.000
K75.8 Other specified inflammatory liver diseases	0.890	0.110	0.000
H05.2 Exophthalmic conditions	0.889	0.111	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.889	0.111	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.888	0.112	0.000
E10.5 With peripheral circulatory complications	0.887	0.113	0.000
G59 Mononeuropathy in diseases classified elsewhere	0.887	0.113	0.000
Q43 Other congenital malformations of intestine	0.886	0.114	0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.886	0.114	0.000
L53 Other erythematous conditions	0.884	0.116	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.883	0.117	0.000
M60 Myositis	0.883	0.117	0.000
M15 Polyarthrosis	0.882	0.118	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.882	0.118	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.880	0.120	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.880	0.120	0.000
I74 Arterial embolism and thrombosis	0.880	0.120	0.000
E06.3 Autoimmune thyroiditis	0.879	0.121	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.879	0.121	0.000
L92 Granulomatous disorders of skin and subcutaneous tissue	0.878	0.122	0.000
H43-H45 Disorders of vitreous body and globe	0.878	0.122	0.000
M07 Psoriatic and enteropathic arthropathies	0.001	0.124	0.876
E10.0 With coma	0.873	0.127	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.873	0.127	0.000
I73.0 Raynaud's syndrome	0.869	0.131	0.000
L97 Ulcer of lower limb, not elsewhere classified	0.869	0.131	0.000
E14.8 With unspecified complications	0.863	0.137	0.000
N40-N51 Diseases of male genital organs	0.004	0.140	0.857
E11.1 With ketoacidosis	0.860	0.140	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.859	0.141	0.000
I77.1 Stricture of artery	0.858	0.142	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.855	0.145	0.000
C91.9 Lymphoid leukaemia, unspecified	0.854	0.146	0.000
B07 Viral warts	0.853	0.147	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.853	0.147	0.000
K74.3 Primary biliary cirrhosis	0.851	0.149	0.000
Chapter II Neoplasms	0.850	0.150	0.000
C88 Malignant immunoproliferative diseases	0.850	0.150	0.000
E14.1 With ketoacidosis	0.850	0.150	0.000
H00 Hordeolum and chalazion	0.145	0.151	0.704
D55-D59 Haemolytic anaemias	0.846	0.154	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.155	0.845
E22 Hyperfunction of pituitary gland	0.844	0.156	0.000
H43 Disorders of vitreous body	0.843	0.157	0.000
I73.9 Peripheral vascular disease, unspecified	0.842	0.158	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.839	0.161	0.000
E28 Ovarian dysfunction	0.835	0.165	0.000
I20-I25 Ischaemic heart diseases	0.835	0.165	0.000
D61 Other aplastic anaemias	0.833	0.167	0.000
N47 Redundant prepuce, phimosis and paraphimosis	0.000	0.169	0.831
E16.0 Drug-induced hypoglycaemia without coma	0.831	0.169	0.000
E07.8 Other specified disorders of thyroid	0.831	0.169	0.000
E10.7 With multiple complications	0.830	0.170	0.000
I24 Other acute ischaemic heart diseases	0.830	0.170	0.000
M35.7 Hypermobility syndrome	0.829	0.171	0.000
I24.8 Other forms of acute ischaemic heart disease	0.829	0.171	0.000
G51.0 Bell's palsy	0.828	0.172	0.000
H05.0 Acute inflammation of orbit	0.827	0.173	0.000
D86 Sarcoidosis	0.826	0.174	0.000
I63.8 Other cerebral infarction	0.825	0.175	0.000
N04.1 Focal and segmental glomerular lesions	0.824	0.176	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.824	0.176	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.177	0.823
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.823	0.177	0.000
C84.5 Other and unspecified T-cell lymphomas	0.823	0.177	0.000
E29 Testicular dysfunction	0.820	0.180	0.000
Q44.6 Cystic disease of liver	0.820	0.180	0.000
L94 Other localised connective tissue disorders	0.819	0.181	0.000
D69.2 Other nonthrombocytopenic purpura	0.819	0.181	0.000
B15-B19 Viral hepatitis	0.819	0.181	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.818	0.182	0.000
M60.9 Myositis, unspecified	0.817	0.183	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.816	0.184	0.000
E11.5 With peripheral circulatory complications	0.815	0.185	0.000
C92 Myeloid leukaemia	0.814	0.186	0.000
D64.8 Other specified anaemias	0.813	0.187	0.000
E34 Other endocrine disorders	0.812	0.188	0.000
M33 Dermatopolymyositis	0.810	0.190	0.000
G55.0 Nerve root and plexus compressions in neoplastic disease	0.810	0.190	0.000
Chapter XIV Diseases of the genitourinary system	0.797	0.190	0.014
D51 Vitamin B12 deficiency anaemia	0.810	0.190	0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.809	0.191	0.000
C81.2 Mixed cellularity	0.809	0.191	0.000
Q61 Cystic kidney disease	0.808	0.192	0.000
G59.0 Diabetic mononeuropathy	0.807	0.193	0.000
M62 Other disorders of muscle	0.806	0.194	0.000
Q39 Congenital malformations of oesophagus	0.805	0.195	0.000
H33 Retinal detachments and breaks	0.805	0.195	0.000
G56.4 Causalgia	0.804	0.196	0.000
Q60.2 Renal agenesis, unspecified	0.803	0.197	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.803	0.197	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.799	0.201	0.000
L52 Erythema nodosum	0.799	0.201	0.000
K38 Other diseases of appendix	0.799	0.201	0.000
E31 Polyglandular dysfunction	0.798	0.202	0.000
K73.9 Chronic hepatitis, unspecified	0.798	0.202	0.000
Q80-Q89 Other congenital malformations	0.798	0.202	0.000
C04 Malignant neoplasm of floor of mouth	0.797	0.203	0.000
D80 Immunodeficiency with predominantly antibody defects	0.797	0.203	0.000
L92.0 Granuloma annulare	0.795	0.205	0.000
I10-I15 Hypertensive diseases	0.794	0.206	0.000
L53.9 Erythematous condition, unspecified	0.793	0.207	0.000
L93 Lupus erythematosus	0.792	0.208	0.000
M06.0 Seronegative rheumatoid arthritis	0.000	0.209	0.791
E11.2 With renal complications	0.790	0.210	0.000
B25-B34 Other viral diseases	0.790	0.210	0.000
E14.5 With peripheral circulatory complications	0.789	0.211	0.000
H43.8 Other disorders of vitreous body	0.789	0.211	0.000
M11 Other crystal arthropathies	0.001	0.212	0.788
M07.3 Other psoriatic arthropathies	0.000	0.212	0.788
Chapter VIII Diseases of the ear and mastoid process	0.788	0.212	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.787	0.213	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.213	0.787
M35.1 Other overlap syndromes	0.786	0.213	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.786	0.214	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.786	0.214	0.000
Q43.9 Congenital malformation of intestine, unspecified	0.786	0.214	0.000
M15.2 Bouchard's nodes (with arthropathy)	0.786	0.214	0.000
E53 Deficiency of other B group vitamins	0.785	0.215	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.215	0.785
K74.5 Biliary cirrhosis, unspecified	0.783	0.217	0.000
E10.8 With unspecified complications	0.782	0.218	0.000
D68 Other coagulation defects	0.782	0.218	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.780	0.219	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.780	0.220	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.779	0.221	0.000
A63.0 Anogenital (venereal) warts	0.778	0.222	0.000
H35 Other retinal disorders	0.778	0.222	0.000
I70 Atherosclerosis	0.778	0.222	0.000
C07 Malignant neoplasm of parotid gland	0.778	0.222	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.777	0.223	0.000
G56.9 Mononeuropathy of upper limb, unspecified	0.776	0.224	0.000
D50.1 Sideropenic dysphagia	0.775	0.224	0.000
E40-E46 Malnutrition	0.774	0.226	0.000
H34 Retinal vascular occlusions	0.774	0.226	0.000
N08.5 Glomerular disorders in systemic connective tissue disorders	0.774	0.226	0.000
G11 Hereditary ataxia	0.772	0.228	0.000
M24 Other specific joint derangements	0.772	0.228	0.000
E21.2 Other hyperparathyroidism	0.771	0.229	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.771	0.229	0.000
C83.1 Small cleaved cell (diffuse)	0.771	0.229	0.000
C83.3 Large cell (diffuse)	0.769	0.231	0.000
D69.5 Secondary thrombocytopenia	0.769	0.231	0.000
H33.3 Retinal breaks without detachment	0.769	0.231	0.000
M06.4 Inflammatory polyarthropathy	0.000	0.231	0.769
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.768	0.232	0.000
N48 Other disorders of penis	0.000	0.233	0.767
L53.0 Toxic erythema	0.764	0.236	0.000
K74.6 Other and unspecified cirrhosis of liver	0.764	0.236	0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified	0.763	0.237	0.000
M86-M90 Other osteopathies	0.762	0.238	0.000
N04.2 Diffuse membranous glomerulonephritis	0.761	0.239	0.000
E20 Hypoparathyroidism	0.760	0.240	0.000
D70 Agranulocytosis	0.760	0.240	0.000
C91.5 Adult T-cell leukaemia	0.759	0.241	0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue	0.758	0.242	0.000
E14.2 Withrenal complications	0.755	0.244	0.000
L83 Acanthosis nigricans	0.755	0.245	0.000
C95 Leukaemia of unspecified cell type	0.755	0.245	0.000
E55 Vitamin D deficiency	0.755	0.245	0.000
M60.99 Myositis, unspecified (Site unspecified)	0.753	0.247	0.000
D86.9 Sarcoidosis, unspecified	0.751	0.249	0.000
Q40 Other congenital malformations of upper alimentary tract	0.750	0.250	0.000
D50.8 Other iron deficiency anaemias	0.749	0.251	0.000
M34.8 Other forms of systemic sclerosis	0.749	0.251	0.000
I12 Hypertensive renal disease	0.749	0.251	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.748	0.252	0.000
B02 Zoster [herpes zoster]	0.747	0.253	0.000
E06.9 Thyroiditis, unspecified	0.747	0.253	0.000
C83.7 Burkitt's tumour	0.746	0.254	0.000
H30 Chorioretinal inflammation	0.746	0.254	0.000
E23 Hypofunction and other disorders of pituitary gland	0.745	0.255	0.000
B35-B49 Mycoses	0.745	0.255	0.000
K72 Hepatic failure, not elsewhere classified	0.744	0.256	0.000
C84.8 Cutaneous T-cell lymphoma, unspecified	0.744	0.256	0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis	0.743	0.257	0.000
M14 Arthropathies in other diseases classified elsewhere	0.001	0.258	0.741
C81.0 Lymphocytic predominance	0.741	0.259	0.000
H43.9 Disorder of vitreous body, unspecified	0.741	0.259	0.000
E14.4 With neurological complications	0.740	0.260	0.000
M34.0 Progressive systemic sclerosis	0.740	0.260	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.739	0.261	0.000
I22 Subsequent myocardial infarction	0.739	0.261	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.739	0.261	0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]	0.737	0.263	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.737	0.263	0.000
N42 Other disorders of prostate	0.000	0.265	0.735
C04.9 Floor of mouth, unspecified	0.735	0.265	0.000
N05.8 Other	0.734	0.266	0.000
M00-M03 Infectious arthropathies	0.734	0.266	0.000
Q35-Q37 Cleft lip and cleft palate	0.732	0.268	0.000
E51 Thiamine deficiency	0.732	0.268	0.000
H60-H62 Diseases of external ear	0.731	0.269	0.000
Q61.3 Polycystic kidney, unspecified	0.729	0.270	0.000
Q60.0 Renal agenesis, unilateral	0.729	0.271	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.729	0.271	0.000
C91.0 Acute lymphoblastic leukaemia	0.728	0.272	0.000
L50 Urticaria	0.728	0.272	0.000
D52 Folate deficiency anaemia	0.728	0.272	0.000
L11 Other acantholytic disorders	0.728	0.272	0.000
H03 Disorders of eyelid in diseases classified elsewhere	0.728	0.272	0.000
B18 Chronic viral hepatitis	0.727	0.273	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.000	0.274	0.726
E27.8 Other specified disorders of adrenal gland	0.725	0.274	0.000
Q50-Q56 Congenital malformations of genital organs	0.725	0.275	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.724	0.276	0.000
L51 Erythema multiforme	0.723	0.277	0.000
C92.0 Acute myeloid leukaemia	0.723	0.277	0.000
G51.9 Disorder of facial nerve, unspecified	0.723	0.277	0.000
Q43.3 Congenital malformations of intestinal fixation	0.722	0.278	0.000
G30-G32 Other degenerative diseases of the nervous system	0.721	0.279	0.000
M34.1 CR(E)ST syndrome	0.720	0.280	0.000
E74 Other disorders of carbohydrate metabolism	0.720	0.280	0.000
E07.9 Disorder of thyroid, unspecified	0.720	0.280	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.720	0.280	0.000
G52 Disorders of other cranial nerves	0.719	0.280	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.718	0.281	0.000
I12.9 Hypertensive renal disease without renal failure	0.718	0.282	0.000
E11.8 With unspecified complications	0.718	0.282	0.000
E05.5 Thyroid crisis or storm	0.717	0.283	0.000
E05.4 Thyrotoxicosis factitia	0.717	0.283	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.717	0.283	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.717	0.283	0.000
E32 Diseases of thymus	0.717	0.283	0.000
E30 Disorders of puberty, not elsewhere classified	0.717	0.283	0.000
E25 Adrenogenital disorders	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
K90.3 Pancreatic steatorrhoea	0.717	0.283	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.717	0.283	0.000
K90.1 Tropical sprue	0.717	0.283	0.000
E03.5 Myxoedema coma	0.717	0.283	0.000
E03.4 Atrophy of thyroid (acquired)	0.717	0.283	0.000
E03.3 Postinfectious hypothyroidism	0.717	0.283	0.000
E03.1 Congenital hypothyroidism without goitre	0.717	0.283	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.717	0.283	0.000
D64.4 Congenital dyserythropoietic anaemia	0.717	0.283	0.000
D64.3 Other sideroblastic anaemias	0.717	0.283	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.717	0.283	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.717	0.283	0.000
D64.0 Hereditary sideroblastic anaemia	0.717	0.283	0.000
E14.7 With multiple complications	0.717	0.283	0.000
E14.0 With coma	0.717	0.283	0.000
D67 Hereditary factor IX deficiency	0.717	0.283	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.717	0.283	0.000
D69.8 Other specified haemorrhagic conditions	0.717	0.283	0.000
D69.1 Qualitative platelet defects	0.717	0.283	0.000
M06.8 Other specified rheumatoid arthritis	0.000	0.283	0.717
M06.2 Rheumatoid bursitis	0.000	0.283	0.717
M06.1 Adult-onset Still's disease	0.000	0.283	0.717
H32 Chorioretinal disorders in diseases classified elsewhere	0.717	0.283	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.717	0.283	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.000	0.283	0.717
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.283	0.717
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.000	0.283	0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.283	0.717
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.000	0.283	0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.000	0.283	0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.000	0.283	0.717
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.283	0.717
M09 Juvenile arthritis in diseases classified elsewhere	0.001	0.283	0.716
M08 Juvenile arthritis	0.001	0.283	0.716
G12 Spinal muscular atrophy and related syndromes	0.716	0.283	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.716	0.284	0.000
M35.8 Other specified systemic involvement of connective tissue	0.716	0.284	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.716	0.284	0.000
M35.5 Multifocal fibrosclerosis	0.716	0.284	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.716	0.284	0.000
M05.8 Other seropositive rheumatoid arthritis	0.001	0.284	0.716
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.001	0.284	0.716
M05.2 Rheumatoid vasculitis	0.001	0.284	0.716
M05.1 Rheumatoid lung disease	0.001	0.284	0.716
M05.0 Felty's syndrome	0.001	0.284	0.716
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.716	0.284	0.000
E15 Nondiabetic hypoglycaemic coma	0.716	0.284	0.000
H80-H83 Diseases of inner ear	0.716	0.284	0.000
K77 Liver disorders in diseases classified elsewhere	0.716	0.284	0.000
K71 Toxic liver disease	0.716	0.284	0.000
K93 Disorders of other digestive organs in diseases classified elsewhere	0.716	0.284	0.000
G57 Mononeuropathies of lower limb	0.716	0.284	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.715	0.284	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.715	0.284	0.000
E16.4 Abnormal secretion of gastrin	0.715	0.284	0.000
E16.3 Increased secretion of glucagon	0.715	0.284	0.000
I67 Other cerebrovascular diseases	0.715	0.285	0.000
E10.6 With other specified complications	0.715	0.285	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.715	0.285	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.715	0.285	0.000
E21.4 Other specified disorders of parathyroid gland	0.715	0.285	0.000
E27.5 Adrenomedullary hyperfunction	0.715	0.285	0.000
E27.0 Other adrenocortical overactivity	0.715	0.285	0.000
D83 Common variable immunodeficiency	0.715	0.285	0.000
E03.8 Other specified hypothyroidism	0.714	0.285	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.714	0.286	0.000
C94 Other leukaemias of specified cell type	0.714	0.286	0.000
C93 Monocytic leukaemia	0.714	0.286	0.000
C86 Other specified types of T/NK-cell lymphoma	0.714	0.286	0.000
D68.0 Von Willebrand's disease	0.714	0.286	0.000
Q00-Q07 Congenital malformations of the nervous system	0.714	0.286	0.000
G14 Postpolio syndrome	0.714	0.286	0.000
K90.8 Other intestinal malabsorption	0.714	0.286	0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint	0.713	0.286	0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral	0.713	0.286	0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint	0.713	0.286	0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral	0.713	0.286	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.713	0.287	0.000
K75.2 Nonspecific reactive hepatitis	0.713	0.287	0.000
K75.1 Phlebitis of portal vein	0.713	0.287	0.000
C84.0 Mycosis fungoides	0.713	0.287	0.000
M80-M85 Disorders of bone density and structure	0.713	0.287	0.000
L82 Seborrhoeic keratosis	0.712	0.288	0.000
E28.2 Polycystic ovarian syndrome	0.712	0.288	0.000
K35.2 Acute appendicitis with generalized peritonitis	0.711	0.289	0.000
E53.8 Deficiency of other specified B group vitamins	0.710	0.290	0.000
H06.3 Other disorders of orbit in diseases classified elsewhere	0.709	0.290	0.000
H06.1 Parasitic infestation of orbit in diseases classified elsewhere	0.709	0.290	0.000
H06.0 Disorders of lachrymal system in diseases classified elsewhere	0.709	0.290	0.000
N05.9 Unspecified	0.709	0.290	0.000
Q44.5 Other congenital malformations of bile ducts	0.709	0.291	0.000
M20 Acquired deformities of fingers and toes	0.002	0.291	0.706
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.708	0.292	0.000
L94.0 Localised scleroderma [morphea]	0.708	0.292	0.000
B25 Cytomegaloviral disease	0.708	0.292	0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.707	0.292	0.000
C85.0 Lymphosarcoma	0.707	0.292	0.000
C81.7 Other Hodgkin's disease	0.706	0.294	0.000
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.706	0.294	0.000
C81.3 Lymphocytic depletion	0.706	0.294	0.000
M86 Osteomyelitis	0.706	0.294	0.000
I79.1 Aortitis in diseases classified elsewhere	0.705	0.295	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.705	0.295	0.000
I00-I02 Acute rheumatic fever	0.705	0.295	0.000
A65-A69 Other spirochaetal diseases	0.704	0.296	0.000
H35.2 Other proliferative retinopathy	0.704	0.296	0.000
Q45 Other congenital malformations of digestive system	0.704	0.296	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.704	0.296	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.704	0.296	0.000
C91.8 Mature B-cell leukaemia Burkitt-type	0.704	0.296	0.000
C91.7 Other lymphoid leukaemia	0.704	0.296	0.000
C91.6 Prolymphocytic leukaemia of T-cell type	0.704	0.296	0.000
C91.3 Prolymphocytic leukaemia	0.704	0.296	0.000
C91.2 Subacute lymphocytic leukaemia	0.704	0.296	0.000
M17.2 Posttraumatic gonarthrosis, bilateral	0.703	0.296	0.000
M60.0 Infective myositis	0.703	0.297	0.000
I74.8 Embolism and thrombosis of other arteries	0.701	0.299	0.000
K75.0 Abscess of liver	0.701	0.299	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.302	0.698
E73 Lactose intolerance	0.698	0.302	0.000
N42.8 Other specified disorders of prostate	0.000	0.303	0.696
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.696	0.304	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.696	0.304	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations