TreeWAS – Variant ID: rs115487693

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.003	0.997
E03.9 Hypothyroidism, unspecified	0.000	0.003	0.997
M06.9 Rheumatoid arthritis, unspecified	0.000	0.004	0.996
E03 Other hypothyroidism	0.000	0.012	0.988
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.013	0.987
E00-E07 Disorders of thyroid gland	0.000	0.018	0.982
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.040	0.960
E10 Insulin-dependent diabetes mellitus	0.000	0.046	0.954
E10-E14 Diabetes mellitus	0.000	0.046	0.954
E10.9 Without complications	0.000	0.050	0.950
E10.3 With ophthalmic complications	0.000	0.114	0.886
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.130	0.870
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.133	0.867
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.134	0.866
K90.0 Coeliac disease	0.855	0.145	0.000
E06 Thyroiditis	0.000	0.155	0.845
M06 Other rheumatoid arthritis	0.000	0.163	0.837
L40.9 Psoriasis, unspecified	0.000	0.172	0.828
L40 Psoriasis	0.000	0.175	0.825
L40.5 Arthropathic psoriasis	0.000	0.179	0.821
E70-E90 Metabolic disorders	0.000	0.199	0.801
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.223	0.777
E04 Other non-toxic goitre	0.000	0.224	0.776
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.231	0.769
E89.0 Postprocedural hypothyroidism	0.000	0.235	0.765
E40-E46 Malnutrition	0.000	0.237	0.763
E50-E64 Other nutritional deficiencies	0.000	0.248	0.752
E06.3 Autoimmune thyroiditis	0.000	0.253	0.747
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.254	0.746
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.264	0.736
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.268	0.732
E10.4 With neurological complications	0.000	0.275	0.725
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.286	0.714
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.286	0.714
E13 Other specified diabetes mellitus	0.000	0.287	0.713
E03.8 Other specified hypothyroidism	0.000	0.288	0.712
E05.9 Thyrotoxicosis, unspecified	0.000	0.290	0.710
E03.5 Myxoedema coma	0.000	0.291	0.708
E03.4 Atrophy of thyroid (acquired)	0.000	0.291	0.708
E03.3 Postinfectious hypothyroidism	0.000	0.291	0.708
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.291	0.708
E03.1 Congenital hypothyroidism without goitre	0.000	0.291	0.708
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.291	0.708
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.296	0.704
E00 Congenital iodine-deficiency syndrome	0.000	0.296	0.704
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.296	0.704
M06.0 Seronegative rheumatoid arthritis	0.000	0.300	0.700
L40-L45 Papulosquamous disorders	0.000	0.305	0.695
E10.8 With unspecified complications	0.000	0.316	0.684
E10.7 With multiple complications	0.000	0.316	0.684
E10.6 With other specified complications	0.000	0.316	0.684
E10.5 With peripheral circulatory complications	0.000	0.316	0.684
E10.2 With renal complications	0.000	0.316	0.684
E10.0 With coma	0.000	0.316	0.684
E12 Malnutrition-related diabetes mellitus	0.000	0.316	0.684
E10.1 With ketoacidosis	0.000	0.316	0.684
E04.2 Non-toxic multinodular goitre	0.000	0.324	0.676
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.327	0.673
M05-M14 Inflammatory polyarthropathies	0.000	0.330	0.670
E65-E68 Obesity and other hyperalimentation	0.000	0.355	0.645
Chapter XII Diseases of the skin and subcutaneous tissue	0.000	0.363	0.637
E88 Other metabolic disorders	0.000	0.363	0.637
E05.8 Other thyrotoxicosis	0.000	0.376	0.623
E05.5 Thyroid crisis or storm	0.000	0.376	0.623
E05.4 Thyrotoxicosis factitia	0.000	0.376	0.623
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.376	0.623
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.376	0.623
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.376	0.623
E86 Volume depletion	0.000	0.379	0.621
E46 Unspecified protein-energy malnutrition	0.000	0.379	0.621
L00-L08 Infections of the skin and subcutaneous tissue	0.000	0.383	0.617
L40.0 Psoriasis vulgaris	0.000	0.394	0.606
E06.9 Thyroiditis, unspecified	0.000	0.394	0.606
E06.5 Other chronic thyroiditis	0.000	0.394	0.606
E06.4 Drug-induced thyroiditis	0.000	0.394	0.606
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.394	0.606
E06.1 Subacute thyroiditis	0.000	0.394	0.606
E06.0 Acute thyroiditis	0.000	0.394	0.606
M06.8 Other specified rheumatoid arthritis	0.000	0.400	0.600
M06.2 Rheumatoid bursitis	0.000	0.400	0.600
M06.1 Adult-onset Still's disease	0.000	0.400	0.600
M07 Psoriatic and enteropathic arthropathies	0.000	0.400	0.600
M06.4 Inflammatory polyarthropathy	0.000	0.404	0.596
L40.8 Other psoriasis	0.000	0.408	0.592
L40.4 Guttate psoriasis	0.000	0.408	0.592
L40.3 Pustulosis palmaris et plantaris	0.000	0.408	0.592
L40.2 Acrodermatitis continua	0.000	0.408	0.592
L40.1 Generalised pustular psoriasis	0.000	0.408	0.592
E55 Vitamin D deficiency	0.000	0.412	0.587
M05 Seropositive rheumatoid arthritis	0.000	0.414	0.586
E07 Other disorders of thyroid	0.000	0.415	0.585
L20-L30 Dermatitis and eczema	0.000	0.418	0.582
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.419	0.581
E53 Deficiency of other B group vitamins	0.000	0.419	0.581
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.000	0.421	0.579
L08 Other local infections of skin and subcutaneous tissue	0.000	0.422	0.578
E14 Unspecified diabetes mellitus	0.000	0.425	0.575
E84 Cystic fibrosis	0.000	0.425	0.575
E79 Disorders of purine and pyrimidine metabolism	0.000	0.425	0.575
E77 Disorders of glycoprotein metabolism	0.000	0.425	0.575
E76 Disorders of glycosaminoglycan metabolism	0.000	0.425	0.575
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.425	0.575
E73 Lactose intolerance	0.000	0.425	0.575
E72 Other disorders of amino-acid metabolism	0.000	0.425	0.575
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.425	0.575
E70 Disorders of aromatic amino-acid metabolism	0.000	0.425	0.575
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.425	0.575
L02 Cutaneous abscess, furuncle and carbuncle	0.000	0.430	0.570
E89.2 Postprocedural hypoparathyroidism	0.000	0.431	0.569
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.000	0.436	0.564
M06.3 Rheumatoid nodule	0.000	0.439	0.561
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.439	0.560
E89.3 Postprocedural hypopituitarism	0.000	0.442	0.558
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.443	0.557
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.443	0.557
E89.5 Postprocedural testicular hypofunction	0.000	0.443	0.557
E89.4 Postprocedural ovarian failure	0.000	0.443	0.557
E89.1 Postprocedural hypoinsulinaemia	0.000	0.443	0.557
E04.8 Other specified non-toxic goitre	0.000	0.444	0.556
E04.0 Non-toxic diffuse goitre	0.000	0.444	0.556
L29 Pruritus	0.000	0.447	0.553
M07.3 Other psoriatic arthropathies	0.000	0.450	0.550
E74 Other disorders of carbohydrate metabolism	0.000	0.453	0.547
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.453	0.547
E45 Retarded development following protein-energy malnutrition	0.000	0.453	0.547
E43 Unspecified severe protein-energy malnutrition	0.000	0.453	0.547
E42 Marasmic kwashiorkor	0.000	0.453	0.547
E41 Nutritional marasmus	0.000	0.453	0.547
E40 Kwashiorkor	0.000	0.453	0.547
E13.9 Without complications	0.000	0.459	0.541
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.000	0.460	0.540
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.461	0.539
E63 Other nutritional deficiencies	0.000	0.461	0.539
E56 Other vitamin deficiencies	0.000	0.461	0.539
E51 Thiamine deficiency	0.000	0.461	0.539
E50 Vitamin A deficiency	0.000	0.461	0.539
E60 Dietary zinc deficiency	0.000	0.461	0.539
E59 Dietary selenium deficiency	0.000	0.461	0.539
E58 Dietary calcium deficiency	0.000	0.461	0.539
E54 Ascorbic acid deficiency	0.000	0.461	0.539
E52 Niacin deficiency [pellagra]	0.000	0.461	0.539
L08.9 Local infection of skin and subcutaneous tissue, unspecified	0.000	0.463	0.537
E87 Other disorders of fluid, electrolyte and acid-base balance	0.000	0.463	0.537
M05.9 Seropositive rheumatoid arthritis, unspecified	0.000	0.473	0.526
E04.9 Non-toxic goitre, unspecified	0.000	0.476	0.524
L02.4 Cutaneous abscess, furuncle and carbuncle of limb	0.000	0.477	0.523
L29.0 Pruritus ani	0.000	0.480	0.519
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.481	0.519
L57 Skin changes due to chronic exposure to nonionising radiation	0.000	0.481	0.519
M07.39 Other psoriatic arthropathies (Site unspecified)	0.000	0.486	0.514
E61 Deficiency of other nutrient elements	0.000	0.488	0.512
E13.8 With unspecified complications	0.000	0.488	0.511
E13.7 With multiple complications	0.000	0.488	0.511
E13.6 With other specified complications	0.000	0.488	0.511
E13.5 With peripheral circulatory complications	0.000	0.488	0.511
E13.4 With neurological complications	0.000	0.488	0.511
E13.3 With ophthalmic complications	0.000	0.488	0.511
E13.2 With renal complications	0.000	0.488	0.511
E13.1 With ketoacidosis	0.000	0.488	0.511
E13.0 With coma	0.000	0.488	0.511
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.000	0.492	0.508
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.495	0.505
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.495	0.505
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.495	0.505
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.495	0.505
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.495	0.505
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.495	0.505
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.495	0.505
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.495	0.505
M06.08 Seronegative rheumatoid arthritis (Other)	0.000	0.498	0.502
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.000	0.498	0.502
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.000	0.498	0.502
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.000	0.498	0.502
M06.04 Seronegative rheumatoid arthritis (Hand)	0.000	0.498	0.502
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.000	0.498	0.502
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.000	0.498	0.502
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.000	0.498	0.502
L44 Other papulosquamous disorders	0.000	0.502	0.498
L41 Parapsoriasis	0.000	0.502	0.498
L45 Papulosquamous disorders in diseases classified elsewhere	0.000	0.502	0.498
E04.1 Non-toxic single thyroid nodule	0.000	0.506	0.494
M11 Other crystal arthropathies	0.000	0.509	0.491
E12.9 Without complications	0.000	0.509	0.490
E12.8 With unspecified complications	0.000	0.509	0.490
E12.7 With multiple complications	0.000	0.509	0.490
E12.6 With other specified complications	0.000	0.509	0.490
E12.5 With peripheral circulatory complications	0.000	0.509	0.490
E12.4 With neurological complications	0.000	0.509	0.490
E12.3 With ophthalmic complications	0.000	0.509	0.490
E12.2 With renal complications	0.000	0.509	0.490
E12.1 With ketoacidosis	0.000	0.509	0.490
E12.0 With coma	0.000	0.509	0.490
M14 Arthropathies in other diseases classified elsewhere	0.000	0.520	0.480
M12 Other specific arthropathies	0.000	0.520	0.480
M09 Juvenile arthritis in diseases classified elsewhere	0.000	0.520	0.480
M08 Juvenile arthritis	0.000	0.520	0.480
L43 Lichen planus	0.000	0.527	0.473
E55.9 Vitamin D deficiency, unspecified	0.000	0.530	0.469
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.532	0.468
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.532	0.468
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.000	0.535	0.465
E67 Other hyperalimentation	0.000	0.537	0.463
E68 Sequelae of hyperalimentation	0.000	0.537	0.463
E65 Localised adiposity	0.000	0.537	0.463
L08.8 Other specified local infections of skin and subcutaneous tissue	0.000	0.537	0.463
E53.8 Deficiency of other specified B group vitamins	0.000	0.541	0.459
L10-L14 Bullous disorders	0.000	0.543	0.457
E88.9 Metabolic disorder, unspecified	0.000	0.543	0.457
E88.8 Other specified metabolic disorders	0.000	0.543	0.457
E88.3 Tumour lysis syndrome	0.000	0.543	0.457
E88.2 Lipomatosis, not elsewhere classified	0.000	0.543	0.457
E88.1 Lipodystrophy, not elsewhere classified	0.000	0.543	0.457
E85 Amyloidosis	0.000	0.544	0.456
E87.7 Fluid overload	0.000	0.550	0.450
E20-E35 Disorders of other endocrine glands	0.000	0.551	0.448
M10 Gout	0.000	0.552	0.448
E87.2 Acidosis	0.000	0.552	0.448
L29.2 Pruritus vulvae	0.000	0.556	0.444
L04 Acute lymphadenitis	0.000	0.557	0.442
L01 Impetigo	0.000	0.557	0.442
L00 Staphylococcal scalded skin syndrome	0.000	0.557	0.442
L27 Dermatitis due to substances taken internally	0.000	0.561	0.439
L28 Lichen simplex chronicus and prurigo	0.000	0.563	0.437
L05 Pilonidal cyst	0.000	0.568	0.432
M06.19 Adult-onset Still's disease (Site unspecified)	0.000	0.570	0.430
M06.18 Adult-onset Still's disease (Other)	0.000	0.570	0.430
M06.17 Adult-onset Still's disease (Ankle and foot)	0.000	0.570	0.430
M06.16 Adult-onset Still's disease (Lower leg)	0.000	0.570	0.430
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.000	0.570	0.430
M06.14 Adult-onset Still's disease (Hand)	0.000	0.570	0.430
M06.13 Adult-onset Still's disease (Forearm)	0.000	0.570	0.430
M06.12 Adult-onset Still's disease (Upper arm)	0.000	0.570	0.430
M06.11 Adult-onset Still's disease (Shoulder region)	0.000	0.570	0.430
M06.10 Adult-onset Still's disease (Multiple sites)	0.000	0.570	0.430
M06.29 Rheumatoid bursitis (Site unspecified)	0.000	0.570	0.430
M06.28 Rheumatoid bursitis (Other)	0.000	0.570	0.430
M06.27 Rheumatoid bursitis (Ankle and foot)	0.000	0.570	0.430
M06.26 Rheumatoid bursitis (Lower leg)	0.000	0.570	0.430
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.000	0.570	0.430
M06.24 Rheumatoid bursitis (Hand)	0.000	0.570	0.430
M06.23 Rheumatoid bursitis (Forearm)	0.000	0.570	0.430
M06.22 Rheumatoid bursitis (Upper arm)	0.000	0.570	0.430
M06.21 Rheumatoid bursitis (Shoulder region)	0.000	0.570	0.430
M06.20 Rheumatoid bursitis (Multiple sites)	0.000	0.570	0.430
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.000	0.570	0.430
M06.88 Other specified rheumatoid arthritis (Other)	0.000	0.570	0.430
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.000	0.570	0.430
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.000	0.570	0.430
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.000	0.570	0.430
M06.84 Other specified rheumatoid arthritis (Hand)	0.000	0.570	0.430
M06.83 Other specified rheumatoid arthritis (Forearm)	0.000	0.570	0.430
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.000	0.570	0.430
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.000	0.570	0.430
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.000	0.570	0.430
M07.6 Other enteropathic arthropathies	0.000	0.570	0.430
M07.5 Arthropathy in ulcerative colitis	0.000	0.570	0.430
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.000	0.570	0.430
M07.2 Psoriatic spondylitis	0.000	0.570	0.430
M07.1 Arthritis mutilans	0.000	0.570	0.430
M07.0 Distal interphalangeal psoriatic arthropathy	0.000	0.570	0.430
L57.0 Actinic keratosis	0.000	0.571	0.429
M06.48 Inflammatory polyarthropathy (Other)	0.000	0.573	0.427
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.000	0.573	0.427
M06.46 Inflammatory polyarthropathy (Lower leg)	0.000	0.573	0.427
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.000	0.573	0.427
M06.44 Inflammatory polyarthropathy (Hand)	0.000	0.573	0.427
M06.43 Inflammatory polyarthropathy (Forearm)	0.000	0.573	0.427
M06.42 Inflammatory polyarthropathy (Upper arm)	0.000	0.573	0.427
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.000	0.573	0.427
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.000	0.573	0.427
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.000	0.577	0.423
E55.0 Rickets, active	0.000	0.579	0.421
M05.8 Other seropositive rheumatoid arthritis	0.000	0.580	0.420
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.000	0.580	0.420
M05.2 Rheumatoid vasculitis	0.000	0.580	0.420
M05.1 Rheumatoid lung disease	0.000	0.580	0.420
M05.0 Felty's syndrome	0.000	0.580	0.420
E07.8 Other specified disorders of thyroid	0.000	0.580	0.419
E07.1 Dyshormogenetic goitre	0.000	0.580	0.419
E07.0 Hypersecretion of calcitonin	0.000	0.580	0.419
E66 Obesity	0.000	0.580	0.419
L25 Unspecified contact dermatitis	0.000	0.582	0.417
L24 Irritant contact dermatitis	0.000	0.582	0.417
L23 Allergic contact dermatitis	0.000	0.582	0.417
L21 Seborrhoeic dermatitis	0.000	0.582	0.417
L26 Exfoliative dermatitis	0.000	0.582	0.417
L22 Diaper [napkin] dermatitis	0.000	0.582	0.417
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.583	0.417
E15 Nondiabetic hypoglycaemic coma	0.000	0.583	0.417
E53.9 Vitamin B deficiency, unspecified	0.000	0.583	0.417
E53.1 Pyridoxine deficiency	0.000	0.583	0.417
E53.0 Riboflavin deficiency	0.000	0.583	0.417
L08.1 Erythrasma	0.000	0.586	0.414
L08.0 Pyoderma	0.000	0.586	0.414
L42 Pityriasis rosea	0.000	0.586	0.414
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock	0.000	0.586	0.414
L29.9 Pruritus, unspecified	0.000	0.587	0.413
E14.8 With unspecified complications	0.000	0.587	0.412
E14.7 With multiple complications	0.000	0.587	0.412
E14.6 With other specified complications	0.000	0.587	0.412
E14.5 With peripheral circulatory complications	0.000	0.587	0.412
E14.4 With neurological complications	0.000	0.587	0.412
E14.2 Withrenal complications	0.000	0.587	0.412
E14.1 With ketoacidosis	0.000	0.587	0.412
E14.0 With coma	0.000	0.587	0.412
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.588	0.412
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.588	0.412
E70.3 Albinism	0.000	0.588	0.412
E70.2 Disorders of tyrosine metabolism	0.000	0.588	0.412
E70.1 Other hyperphenylalaninaemias	0.000	0.588	0.412
E70.0 Classical phenylketonuria	0.000	0.588	0.412
E71.3 Disorders of fatty-acid metabolism	0.000	0.588	0.412
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.588	0.412
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.588	0.412
E71.0 Maple-syrup-urine disease	0.000	0.588	0.412
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.588	0.412
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.588	0.412
E72.5 Disorders of glycine metabolism	0.000	0.588	0.412
E72.4 Disorders of ornithine metabolism	0.000	0.588	0.412
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.588	0.412
E72.2 Disorders of urea cycle metabolism	0.000	0.588	0.412
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.588	0.412
E72.0 Disorders of amino-acid transport	0.000	0.588	0.412
E73.9 Lactose intolerance, unspecified	0.000	0.588	0.412
E73.8 Other lactose intolerance	0.000	0.588	0.412
E73.1 Secondary lactase deficiency	0.000	0.588	0.412
E73.0 Congenital lactase deficiency	0.000	0.588	0.412
E75.6 Lipid storage disorder, unspecified	0.000	0.588	0.412
E75.5 Other lipid storage disorders	0.000	0.588	0.412
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.588	0.412
E75.3 Sphingolipidosis, unspecified	0.000	0.588	0.412
E75.2 Other sphingolipidosis	0.000	0.588	0.412
E75.1 Other gangliosidosis	0.000	0.588	0.412
E75.0 GM2 gangliosidosis	0.000	0.588	0.412
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.588	0.412
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.588	0.412
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.588	0.412
E76.2 Other mucopolysaccharidoses	0.000	0.588	0.412
E76.1 Mucopolysaccharidosis, type II	0.000	0.588	0.412
E76.0 Mucopolysaccharidosis, type I	0.000	0.588	0.412
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.588	0.412
E77.8 Other disorders of glycoprotein metabolism	0.000	0.588	0.412
E77.1 Defects in glycoprotein degradation	0.000	0.588	0.412
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.588	0.412
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.588	0.412
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.588	0.412
E79.1 Lesch-Nyhan syndrome	0.000	0.588	0.412
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.588	0.412
E84.9 Cystic fibrosis, unspecified	0.000	0.588	0.412
E84.8 Cystic fibrosis with other manifestations	0.000	0.588	0.412
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.588	0.412
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.588	0.412
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites	0.000	0.591	0.409
L59 Other disorders of skin and subcutaneous tissue related to radiation	0.000	0.595	0.405
L58 Radiodermatitis	0.000	0.595	0.405
L55 Sunburn	0.000	0.595	0.405
M06.39 Rheumatoid nodule (Site unspecified)	0.000	0.597	0.402
M06.38 Rheumatoid nodule (Other)	0.000	0.597	0.402
M06.37 Rheumatoid nodule (Ankle and foot)	0.000	0.597	0.402
M06.36 Rheumatoid nodule (Lower leg)	0.000	0.597	0.402
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.000	0.597	0.402
M06.33 Rheumatoid nodule (Forearm)	0.000	0.597	0.402
M06.32 Rheumatoid nodule (Upper arm)	0.000	0.597	0.402
M06.31 Rheumatoid nodule (Shoulder region)	0.000	0.597	0.402
M06.30 Rheumatoid nodule (Multiple sites)	0.000	0.597	0.402
E80.7 Disorder of bilirubin metabolism, unspecified	0.000	0.598	0.402
E80.6 Other disorders of bilirubin metabolism	0.000	0.598	0.402
E80.5 Crigler-Najjar syndrome	0.000	0.598	0.402
E80.3 Defects of catalase and peroxydase	0.000	0.598	0.402
E80.2 Other porphyria	0.000	0.598	0.402
E80.1 Porphyria cutanea tarda	0.000	0.598	0.402
E80.0 Hereditary erythropoietic porphyria	0.000	0.598	0.402
L29.8 Other pruritus	0.000	0.603	0.397
L29.3 Anogenital pruritus, unspecified	0.000	0.603	0.397
L29.1 Pruritus scroti	0.000	0.603	0.397
M07.38 Other psoriatic arthropathies (Other)	0.000	0.606	0.394
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.000	0.606	0.394
M07.36 Other psoriatic arthropathies (Lower leg)	0.000	0.606	0.394
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.000	0.606	0.394
M07.34 Other psoriatic arthropathies (Hand)	0.000	0.606	0.394
M07.33 Other psoriatic arthropathies (Forearm)	0.000	0.606	0.394
M07.32 Other psoriatic arthropathies (Upper arm)	0.000	0.606	0.394
M07.31 Other psoriatic arthropathies (Shoulder region)	0.000	0.606	0.394
M07.30 Other psoriatic arthropathies (Multiple sites)	0.000	0.606	0.394
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.607	0.392
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.607	0.392
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.607	0.392
E74.2 Disorders of galactose metabolism	0.000	0.607	0.392
E74.1 Disorders of fructose metabolism	0.000	0.607	0.392
E74.0 Glycogen storage disease	0.000	0.607	0.392
E44.1 Mild protein-energy malnutrition	0.000	0.608	0.392
E44.0 Moderate protein-energy malnutrition	0.000	0.608	0.392
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.000	0.609	0.391
E80.4 Gilbert's syndrome	0.000	0.612	0.388
L20 Atopic dermatitis	0.000	0.612	0.388
E50.9 Vitamin A deficiency, unspecified	0.000	0.613	0.387
E50.8 Other manifestations of vitamin A deficiency	0.000	0.613	0.387
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.613	0.387
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.613	0.387
E50.5 Vitamin A deficiency with night blindness	0.000	0.613	0.387
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.613	0.387
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.613	0.387
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.613	0.387
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.613	0.387
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.613	0.387
E51.9 Thiamine deficiency, unspecified	0.000	0.613	0.387
E51.8 Other manifestations of thiamine deficiency	0.000	0.613	0.387
E51.2 Wernicke's encephalopathy	0.000	0.613	0.387
E51.1 Beriberi	0.000	0.613	0.387
E56.9 Vitamin deficiency, unspecified	0.000	0.613	0.387
E56.8 Deficiency of other vitamins	0.000	0.613	0.387
E56.1 Deficiency of vitamin K	0.000	0.613	0.387
E56.0 Deficiency of vitamin E	0.000	0.613	0.387
E63.9 Nutritional deficiency, unspecified	0.000	0.613	0.387
E63.8 Other specified nutritional deficiencies	0.000	0.613	0.387
E63.1 Imbalance of constituents of food intake	0.000	0.613	0.387
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.613	0.387
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.613	0.387
E64.8 Sequelae of other nutritional deficiencies	0.000	0.613	0.387
E64.3 Sequelae of rickets	0.000	0.613	0.387
E64.2 Sequelae of vitamin C deficiency	0.000	0.613	0.387
E64.1 Sequelae of vitamin A deficiency	0.000	0.613	0.387
E64.0 Sequelae of protein-energy malnutrition	0.000	0.613	0.387
L03 Cellulitis	0.000	0.614	0.386
E87.4 Mixed disorder of acid-base balance	0.000	0.615	0.385
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified	0.000	0.618	0.382
E27 Other disorders of adrenal gland	0.000	0.619	0.381
L56 Other acute skin changes due to ultraviolet radiation	0.000	0.619	0.381
L02.0 Cutaneous abscess, furuncle and carbuncle of face	0.000	0.619	0.380
E87.3 Alkalosis	0.000	0.622	0.378
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.000	0.622	0.378
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.622	0.378
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.000	0.622	0.378
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.622	0.378
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.000	0.622	0.378
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.000	0.622	0.378
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.000	0.622	0.378
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.622	0.378
E66.8 Other obesity	0.000	0.628	0.372
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified	0.000	0.628	0.372
L57.5 Actinic granuloma	0.000	0.628	0.372
L57.4 Cutis laxa senilis	0.000	0.628	0.372
L57.3 Poikiloderma of Civatte	0.000	0.628	0.372
L57.2 Cutis rhomboidalis nuchae	0.000	0.628	0.372
L57.1 Actinic reticuloid	0.000	0.628	0.372
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.631	0.369
E14.3 With ophthalmic complications	0.000	0.632	0.368
E61.9 Deficiency of nutrient element, unspecified	0.000	0.633	0.367
E61.8 Deficiency of other specified nutrient elements	0.000	0.633	0.367
E61.7 Deficiency of multiple nutrient elements	0.000	0.633	0.367
E61.6 Vanadium deficiency	0.000	0.633	0.367
E61.5 Molybdenum deficiency	0.000	0.633	0.367
E61.4 Chromium deficiency	0.000	0.633	0.367
E61.3 Manganese deficiency	0.000	0.633	0.367
E61.2 Magnesium deficiency	0.000	0.633	0.367
E61.0 Copper deficiency	0.000	0.633	0.367
E74.3 Other disorders of intestinal carbohydrate absorption	0.000	0.635	0.365
M06.34 Rheumatoid nodule (Hand)	0.000	0.636	0.364
M11.2 Other chondrocalcinosis	0.000	0.637	0.363
E14.9 Without complications	0.000	0.638	0.362
L41.9 Parapsoriasis, unspecified	0.000	0.642	0.357
L41.8 Other parapsoriasis	0.000	0.642	0.357
L41.5 Retiform parapsoriasis	0.000	0.642	0.357
L41.4 Large plaque parapsoriasis	0.000	0.642	0.357
L41.3 Small plaque parapsoriasis	0.000	0.642	0.357
L41.2 Lymphomatoid papulosis	0.000	0.642	0.357
L41.1 Pityriasis lichenoides chronica	0.000	0.642	0.357
L41.0 Pityriasis lichenoides et varioliformis acuta	0.000	0.642	0.357
L44.9 Papulosquamous disorder, unspecified	0.000	0.642	0.357
L44.8 Other specified papulosquamous disorders	0.000	0.642	0.357
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.000	0.642	0.357
L44.3 Lichen ruber moniliformis	0.000	0.642	0.357
L44.2 Lichen striatus	0.000	0.642	0.357
L44.1 Lichen nitidus	0.000	0.642	0.357
L44.0 Pityriasis rubra pilaris	0.000	0.642	0.357
E87.1 Hypo-osmolality and hyponatraemia	0.000	0.644	0.356
M11.9 Crystal arthropathy, unspecified	0.000	0.648	0.352
M11.8 Other specified crystal arthropathies	0.000	0.648	0.352
M11.1 Familial chondrocalcinosis	0.000	0.648	0.352
M11.0 Hydroxyapatite deposition disease	0.000	0.648	0.352
E87.5 Hyperkalaemia	0.000	0.652	0.348
# Top node	0.000	0.654	0.346
M08.9 Juvenile arthritis, unspecified	0.000	0.655	0.344
M08.8 Other juvenile arthritis	0.000	0.655	0.344
M08.4 Pauciarticular juvenile arthritis	0.000	0.655	0.344
M08.3 Juvenile polyarthritis (seronegative)	0.000	0.655	0.344
M08.2 Juvenile arthritis with systemic onset	0.000	0.655	0.344
M08.1 Juvenile ankylosing spondylitis	0.000	0.655	0.344
M08.0 Juvenile rheumatoid arthritis	0.000	0.655	0.344
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.000	0.655	0.344
M09.2 Juvenile arthritis in ulcerative colitis	0.000	0.655	0.344
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.000	0.655	0.344
M09.0 Juvenile arthritis in psoriasis	0.000	0.655	0.344
M12.8 Other specific arthropathies, not elsewhere classified	0.000	0.655	0.344
M12.5 Traumatic arthropathy	0.000	0.655	0.344
M12.4 Intermittent hydrarthrosis	0.000	0.655	0.344
M12.3 Palindromic rheumatism	0.000	0.655	0.344
M12.2 Villonodular synovitis (pigmented)	0.000	0.655	0.344
M12.1 Kaschin-Beck disease	0.000	0.655	0.344
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.000	0.655	0.344

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations