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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs11575845
log Bayes Factor = 18.1968
Chromosome 6   position 31,692,386  (GRCh37) Explore rs11575845 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
L40-L45 Papulosquamous disorders
0.000 0.001 0.999
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.001 0.999
L40.9 Psoriasis, unspecified
0.000 0.001 0.999
E10.9 Without complications
0.000 0.001 0.999
K90.0 Coeliac disease
0.998 0.002 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.002 0.998
M06 Other rheumatoid arthritis
0.000 0.003 0.997
L40.5 Arthropathic psoriasis
0.000 0.005 0.995
M05-M14 Inflammatory polyarthropathies
0.000 0.008 0.992
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.011 0.989
E10.3 With ophthalmic complications
0.000 0.015 0.985
L20-L30 Dermatitis and eczema
0.000 0.016 0.984
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.017 0.983
# Top node
0.000 0.025 0.975
L29 Pruritus
0.000 0.033 0.967
E70-E90 Metabolic disorders
0.000 0.033 0.967
L57.0 Actinic keratosis
0.000 0.036 0.964
M07 Psoriatic and enteropathic arthropathies
0.000 0.040 0.960
Chapter X Diseases of the respiratory system
0.000 0.051 0.949
L29.0 Pruritus ani
0.000 0.054 0.946
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.055 0.945
M05 Seropositive rheumatoid arthritis
0.000 0.061 0.939
J80-J84 Other respiratory diseases principally affecting the interstitium
0.000 0.062 0.938
M07.3 Other psoriatic arthropathies
0.000 0.063 0.937
D50-D53 Nutritional anaemias
0.000 0.080 0.920
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.083 0.917
L00-L08 Infections of the skin and subcutaneous tissue
0.000 0.090 0.910
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.092 0.908
M06.0 Seronegative rheumatoid arthritis
0.000 0.094 0.906
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.098 0.902
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.100 0.900
J81 Pulmonary oedema
0.000 0.103 0.897
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.104 0.896
E06 Thyroiditis
0.000 0.104 0.896
D50 Iron deficiency anaemia
0.000 0.106 0.894
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.110 0.890
E50-E64 Other nutritional deficiencies
0.000 0.115 0.885
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.125 0.875
E89.0 Postprocedural hypothyroidism
0.000 0.135 0.865
E10.1 With ketoacidosis
0.000 0.136 0.864
J80 Adult respiratory distress syndrome
0.000 0.139 0.861
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.141 0.859
J09-J18 Influenza and pneumonia
0.000 0.152 0.848
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.154 0.846
E86 Volume depletion
0.000 0.156 0.844
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.158 0.842
Chapter VII Diseases of the eye and adnexa
0.000 0.158 0.842
L08 Other local infections of skin and subcutaneous tissue
0.000 0.165 0.835
L02 Cutaneous abscess, furuncle and carbuncle
0.000 0.166 0.834
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.172 0.828
E10.4 With neurological complications
0.000 0.176 0.824
E06.3 Autoimmune thyroiditis
0.000 0.178 0.822
L29.9 Pruritus, unspecified
0.000 0.184 0.816
D50.9 Iron deficiency anaemia, unspecified
0.000 0.185 0.815
J20-J22 Other acute lower respiratory infections
0.000 0.187 0.813
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.000 0.188 0.812
E87.1 Hypo-osmolality and hyponatraemia
0.000 0.204 0.796
L28 Lichen simplex chronicus and prurigo
0.000 0.205 0.795
E53 Deficiency of other B group vitamins
0.000 0.205 0.795
L27 Dermatitis due to substances taken internally
0.000 0.206 0.794
H02 Other disorders of eyelid
0.000 0.207 0.793
E87.7 Fluid overload
0.000 0.210 0.790
J18 Pneumonia, organism unspecified
0.000 0.213 0.787
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.215 0.785
D60-D64 Aplastic and other anaemias
0.000 0.218 0.782
D80-D89 Certain disorders involving the immune mechanism
0.000 0.219 0.781
J84 Other interstitial pulmonary diseases
0.000 0.221 0.779
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.222 0.778
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.000 0.222 0.778
L40.0 Psoriasis vulgaris
0.000 0.223 0.777
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.224 0.776
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.000 0.226 0.774
E73 Lactose intolerance
0.000 0.228 0.772
J40-J47 Chronic lower respiratory diseases
0.000 0.233 0.767
H02.1 Ectropion of eyelid
0.000 0.234 0.766
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.241 0.759
E40-E46 Malnutrition
0.000 0.243 0.757
M14 Arthropathies in other diseases classified elsewhere
0.000 0.245 0.755
D50.8 Other iron deficiency anaemias
0.000 0.246 0.754
Chapter XXII Codes for special purposes
0.000 0.254 0.746
E65-E68 Obesity and other hyperalimentation
0.000 0.258 0.742
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.259 0.741
H55-H59 Other disorders of eye and adnexa
0.000 0.262 0.738
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.267 0.733
J47 Bronchiectasis
0.000 0.269 0.731
E53.8 Deficiency of other specified B group vitamins
0.000 0.270 0.730
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.270 0.730
J30-J39 Other diseases of upper respiratory tract
0.000 0.271 0.729
H02.0 Entropion and trichiasis of eyelid
0.000 0.273 0.727
Chapter I Certain infectious and parasitic diseases
0.000 0.273 0.727
D51 Vitamin B12 deficiency anaemia
0.000 0.275 0.725
J18.9 Pneumonia, unspecified
0.000 0.276 0.724
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.277 0.723
H04 Disorders of lachrymal system
0.000 0.277 0.723
E87.2 Acidosis
0.000 0.277 0.723
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.277 0.723
D61 Other aplastic anaemias
0.000 0.277 0.723
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.282 0.718
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
E10.8 With unspecified complications
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E10.5 With peripheral circulatory complications
0.000 0.283 0.717
E10.2 With renal complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
L40.8 Other psoriasis
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.3 Pustulosis palmaris et plantaris
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
L44 Other papulosquamous disorders
0.000 0.283 0.716
L41 Parapsoriasis
0.000 0.283 0.716
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.283 0.716
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.283 0.717
L10-L14 Bullous disorders
0.000 0.283 0.716
M06.8 Other specified rheumatoid arthritis
0.000 0.285 0.714
M06.2 Rheumatoid bursitis
0.000 0.285 0.714
M06.1 Adult-onset Still's disease
0.000 0.285 0.714
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.000 0.286 0.713
M12 Other specific arthropathies
0.000 0.289 0.711
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.289 0.711
M08 Juvenile arthritis
0.000 0.289 0.711
Chapter VIII Diseases of the ear and mastoid process
0.000 0.289 0.711
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.291 0.709
L58 Radiodermatitis
0.000 0.291 0.709
L55 Sunburn
0.000 0.291 0.709
J10 Influenza due to identified influenza virus
0.000 0.294 0.706
L25 Unspecified contact dermatitis
0.000 0.295 0.705
L24 Irritant contact dermatitis
0.000 0.295 0.705
L23 Allergic contact dermatitis
0.000 0.295 0.705
L21 Seborrhoeic dermatitis
0.000 0.295 0.705
L26 Exfoliative dermatitis
0.000 0.295 0.705
L22 Diaper [napkin] dermatitis
0.000 0.295 0.705
E88 Other metabolic disorders
0.000 0.295 0.705
J18.1 Lobar pneumonia, unspecified
0.000 0.295 0.705
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.295 0.704
L57.5 Actinic granuloma
0.000 0.295 0.704
L57.4 Cutis laxa senilis
0.000 0.295 0.704
L57.3 Poikiloderma of Civatte
0.000 0.295 0.704
L57.2 Cutis rhomboidalis nuchae
0.000 0.295 0.704
L57.1 Actinic reticuloid
0.000 0.295 0.704
D55-D59 Haemolytic anaemias
0.000 0.296 0.704
L43 Lichen planus
0.000 0.296 0.704
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.000 0.300 0.700
E55 Vitamin D deficiency
0.000 0.301 0.699
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.301 0.699
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.302 0.698
H53-H54 Visual disturbances and blindness
0.000 0.305 0.695
D52 Folate deficiency anaemia
0.000 0.306 0.694
L29.8 Other pruritus
0.000 0.306 0.694
L29.3 Anogenital pruritus, unspecified
0.000 0.306 0.694
L29.1 Pruritus scroti
0.000 0.306 0.694
L29.2 Pruritus vulvae
0.000 0.306 0.694
E84 Cystic fibrosis
0.000 0.306 0.693
E79 Disorders of purine and pyrimidine metabolism
0.000 0.306 0.693
E77 Disorders of glycoprotein metabolism
0.000 0.306 0.693
E76 Disorders of glycosaminoglycan metabolism
0.000 0.306 0.693
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.306 0.693
E72 Other disorders of amino-acid metabolism
0.000 0.306 0.693
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.306 0.693
E70 Disorders of aromatic amino-acid metabolism
0.000 0.306 0.693
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.306 0.693
J32 Chronic sinusitis
0.000 0.308 0.692
E13 Other specified diabetes mellitus
0.000 0.308 0.692
D86 Sarcoidosis
0.000 0.309 0.691
L20 Atopic dermatitis
0.000 0.309 0.691
J22 Unspecified acute lower respiratory infection
0.000 0.311 0.689
H30-H36 Disorders of choroid and retina
0.000 0.312 0.688
M07.6 Other enteropathic arthropathies
0.000 0.312 0.688
M07.5 Arthropathy in ulcerative colitis
0.000 0.312 0.688
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.312 0.688
M07.2 Psoriatic spondylitis
0.000 0.312 0.688
M07.1 Arthritis mutilans
0.000 0.312 0.688
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.312 0.688
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.000 0.318 0.682
L27.0 Generalised skin eruption due to drugs and medicaments
0.000 0.319 0.681
D61.9 Aplastic anaemia, unspecified
0.000 0.320 0.680
J14 Pneumonia due to Haemophilus influenzae
0.000 0.322 0.678
M06.3 Rheumatoid nodule
0.000 0.323 0.677
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.323 0.677
E14 Unspecified diabetes mellitus
0.000 0.326 0.674
M05.8 Other seropositive rheumatoid arthritis
0.000 0.327 0.673
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.327 0.673
M05.2 Rheumatoid vasculitis
0.000 0.327 0.673
M05.1 Rheumatoid lung disease
0.000 0.327 0.673
M05.0 Felty's syndrome
0.000 0.327 0.673
B35-B49 Mycoses
0.000 0.327 0.673
M60-M63 Disorders of muscles
0.000 0.327 0.673
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.328 0.672
M07.38 Other psoriatic arthropathies (Other)
0.000 0.328 0.672
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.328 0.672
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.328 0.672
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.328 0.672
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.328 0.672
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.328 0.672
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.328 0.672
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.328 0.672
M11 Other crystal arthropathies
0.000 0.331 0.669
E05.9 Thyrotoxicosis, unspecified
0.000 0.332 0.668
H02.4 Ptosis of eyelid
0.000 0.339 0.661
L28.0 Lichen simplex chronicus
0.000 0.340 0.660
E74 Other disorders of carbohydrate metabolism
0.000 0.342 0.658
J84.1 Other interstitial pulmonary diseases with fibrosis
0.000 0.342 0.658
L04 Acute lymphadenitis
0.000 0.347 0.652
L01 Impetigo
0.000 0.347 0.652
L00 Staphylococcal scalded skin syndrome
0.000 0.347 0.652
B37 Candidiasis
0.000 0.348 0.652
E03.8 Other specified hypothyroidism
0.000 0.348 0.652
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.350 0.649
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.350 0.649
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.350 0.649
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.350 0.649
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.350 0.649
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.350 0.649
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.350 0.649
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.350 0.649
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock
0.000 0.351 0.649
H04.2 Epiphora
0.000 0.352 0.648
B25-B34 Other viral diseases
0.000 0.353 0.647
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.353 0.646
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.353 0.646
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.353 0.646
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.353 0.646
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.353 0.646
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.353 0.646
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.353 0.646
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.353 0.646
B37.8 Candidiasis of other sites
0.000 0.353 0.647
M00-M03 Infectious arthropathies
0.000 0.354 0.646
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.355 0.645
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.355 0.645
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.355 0.645
E89.5 Postprocedural testicular hypofunction
0.000 0.355 0.645
E89.4 Postprocedural ovarian failure
0.000 0.355 0.645
E89.1 Postprocedural hypoinsulinaemia
0.000 0.355 0.645
H36 Retinal disorders in diseases classified elsewhere
0.000 0.355 0.645
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.355 0.645
D53 Other nutritional anaemias
0.000 0.357 0.643
E06.5 Other chronic thyroiditis
0.000 0.357 0.642
E06.4 Drug-induced thyroiditis
0.000 0.357 0.642
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.357 0.642
E06.1 Subacute thyroiditis
0.000 0.357 0.642
E06.0 Acute thyroiditis
0.000 0.357 0.642
J11 Influenza, virus not identified
0.000 0.359 0.641
D50.1 Sideropenic dysphagia
0.000 0.359 0.641
E06.9 Thyroiditis, unspecified
0.000 0.359 0.641
H02.6 Xanthelasma of eyelid
0.000 0.359 0.641
J82 Pulmonary eosinophilia, not elsewhere classified
0.000 0.361 0.639
J35 Chronic diseases of tonsils and adenoids
0.000 0.363 0.637
H04.5 Stenosis and insufficiency of lachrymal passages
0.000 0.363 0.637
M10 Gout
0.000 0.363 0.637
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.365 0.635
H53 Visual disturbances
0.000 0.365 0.635
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.366 0.634
E63 Other nutritional deficiencies
0.000 0.366 0.634
E56 Other vitamin deficiencies
0.000 0.366 0.634
E51 Thiamine deficiency
0.000 0.366 0.634
E50 Vitamin A deficiency
0.000 0.366 0.634
E60 Dietary zinc deficiency
0.000 0.366 0.634
E59 Dietary selenium deficiency
0.000 0.366 0.634
E58 Dietary calcium deficiency
0.000 0.366 0.634
E54 Ascorbic acid deficiency
0.000 0.366 0.634
E52 Niacin deficiency [pellagra]
0.000 0.366 0.634
J20 Acute bronchitis
0.000 0.368 0.632
E73.9 Lactose intolerance, unspecified
0.000 0.368 0.631
J42 Unspecified chronic bronchitis
0.000 0.371 0.629
E87.4 Mixed disorder of acid-base balance
0.000 0.372 0.628
E87.3 Alkalosis
0.000 0.381 0.619
M80-M85 Disorders of bone density and structure
0.000 0.382 0.618
E89.3 Postprocedural hypopituitarism
0.000 0.382 0.617
H55 Nystagmus and other irregular eye movements
0.000 0.383 0.617
H05 Disorders of orbit
0.000 0.383 0.617
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.384 0.616
H36.0 Diabetic retinopathy
0.000 0.385 0.615
E80.4 Gilbert's syndrome
0.000 0.385 0.615
L08.8 Other specified local infections of skin and subcutaneous tissue
0.000 0.386 0.613
M91-M94 Chondropathies
0.000 0.388 0.612
J32.8 Other chronic sinusitis
0.000 0.389 0.611
H57 Other disorders of eye and adnexa
0.000 0.389 0.611
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.000 0.390 0.610
J17 Pneumonia in diseases classified elsewhere
0.000 0.392 0.608
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.000 0.392 0.608
J09 Influenza due to certain identified influenza virus
0.000 0.392 0.608
H65-H75 Diseases of middle ear and mastoid
0.000 0.394 0.606
L42 Pityriasis rosea
0.000 0.396 0.604
E05.5 Thyroid crisis or storm
0.000 0.396 0.604
E05.4 Thyrotoxicosis factitia
0.000 0.396 0.604
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.396 0.604
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.396 0.604
J10.1 Influenza with other respiratory manifestations, influenza virus identified
0.000 0.396 0.604
J35.0 Chronic tonsillitis
0.000 0.397 0.603
L05 Pilonidal cyst
0.000 0.398 0.602
M06.4 Inflammatory polyarthropathy
0.000 0.398 0.602
H02.5 Other disorders affecting eyelid function
0.000 0.399 0.601
L08.1 Erythrasma
0.000 0.401 0.599
L08.0 Pyoderma
0.000 0.401 0.599
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites
0.000 0.402 0.598
J40 Bronchitis, not specified as acute or chronic
0.000 0.403 0.597
E85 Amyloidosis
0.000 0.404 0.596
E87.5 Hyperkalaemia
0.000 0.409 0.591
J32.0 Chronic maxillary sinusitis
0.000 0.409 0.590
L30 Other dermatitis
0.000 0.411 0.589
E89.2 Postprocedural hypoparathyroidism
0.000 0.414 0.586
H40-H42 Glaucoma
0.000 0.414 0.586
M14.6 Neuropathic arthropathy
0.000 0.415 0.585
D86.0 Sarcoidosis of lung
0.000 0.416 0.584
M80 Osteoporosis with pathological fracture
0.000 0.417 0.583
J21 Acute bronchiolitis
0.000 0.417 0.583
E46 Unspecified protein-energy malnutrition
0.000 0.417 0.582
D86.9 Sarcoidosis, unspecified
0.000 0.418 0.582
J33 Nasal polyp
0.000 0.420 0.580
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.000 0.421 0.579
H72 Perforation of tympanic membrane
0.000 0.422 0.578
B20-B24 Human immunodeficiency virus [HIV] disease
0.000 0.422 0.578
H60-H62 Diseases of external ear
0.000 0.422 0.578
J32.9 Chronic sinusitis, unspecified
0.000 0.422 0.578
J15 Bacterial pneumonia, not elsewhere classified
0.000 0.425 0.575
E61 Deficiency of other nutrient elements
0.000 0.425 0.575
J84.9 Interstitial pulmonary disease, unspecified
0.000 0.430 0.570
L28.2 Other prurigo
0.000 0.430 0.570
L28.1 Prurigo nodularis
0.000 0.430 0.570
E53.9 Vitamin B deficiency, unspecified
0.000 0.430 0.570
E53.1 Pyridoxine deficiency
0.000 0.430 0.570
E53.0 Riboflavin deficiency
0.000 0.430 0.570
L27.9 Dermatitis due to unspecified substance taken internally
0.000 0.431 0.569
L27.8 Dermatitis due to other substances taken internally
0.000 0.431 0.569
L27.2 Dermatitis due to ingested food
0.000 0.431 0.569
H02.7 Other degenerative disorders of eyelid and periocular area
0.000 0.432 0.568
A50-A64 Infections with a predominantly sexual mode of transmission
0.000 0.432 0.568
E55.9 Vitamin D deficiency, unspecified
0.000 0.434 0.566
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.435 0.565
J18.2 Hypostatic pneumonia, unspecified
0.000 0.436 0.564
E66 Obesity
0.000 0.438 0.562
H10-H13 Disorders of conjunctiva
0.000 0.438 0.562
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified
0.000 0.438 0.562
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.439 0.561
D84 Other immunodeficiencies
0.000 0.440 0.560
D83 Common variable immunodeficiency
0.000 0.440 0.560
D82 Immunodeficiency associated with other major defects
0.000 0.440 0.560
D81 Combined immunodeficiencies
0.000 0.440 0.560
D64 Other anaemias
0.000 0.440 0.560
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.440 0.560
E04 Other non-toxic goitre
0.000 0.441 0.559
J84.8 Other specified interstitial pulmonary diseases
0.000 0.442 0.558
J84.0 Alveolar and parietoalveolar conditions
0.000 0.442 0.558
H46 Optic neuritis
0.000 0.443 0.557
D59 Acquired haemolytic anaemia
0.000 0.444 0.556
H02.2 Lagophthalmos
0.000 0.446 0.554
H01 Other inflammation of eyelid
0.000 0.446 0.554
E73.8 Other lactose intolerance
0.000 0.447 0.553
E73.1 Secondary lactase deficiency
0.000 0.447 0.553
E73.0 Congenital lactase deficiency
0.000 0.447 0.553
H53.1 Subjective visual disturbances
0.000 0.447 0.553
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.448 0.552
H72.9 Perforation of tympanic membrane, unspecified
0.000 0.448 0.552
B34 Viral infection of unspecified site
0.000 0.448 0.552
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.448 0.551
J41 Simple and mucopurulent chronic bronchitis
0.000 0.450 0.550
E07 Other disorders of thyroid
0.000 0.451 0.549
M80.9 Unspecified osteoporosis with pathological fracture
0.000 0.453 0.547
M95.0 Acquired deformity of nose
0.000 0.454 0.546
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.000 0.454 0.545
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.457 0.543
E45 Retarded development following protein-energy malnutrition
0.000 0.457 0.543
E43 Unspecified severe protein-energy malnutrition
0.000 0.457 0.543
E42 Marasmic kwashiorkor
0.000 0.457 0.543
E41 Nutritional marasmus
0.000 0.457 0.543
E40 Kwashiorkor
0.000 0.457 0.543
M14.8 Arthropathies in other specified diseases classified elsewhere
0.000 0.459 0.541
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.000 0.459 0.541
M14.4 Arthropathy in amyloidosis
0.000 0.459 0.541
M14.3 Lipoid dermatoarthritis
0.000 0.459 0.541
M14.2 Diabetic arthropathy
0.000 0.459 0.541
M14.1 Crystal arthropathy in other metabolic disorders
0.000 0.459 0.541
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.000 0.459 0.541
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.000 0.460 0.540
L02.0 Cutaneous abscess, furuncle and carbuncle of face
0.000 0.461 0.539
B25 Cytomegaloviral disease
0.000 0.464 0.535
E20-E35 Disorders of other endocrine glands
0.000 0.466 0.534
E66.8 Other obesity
0.000 0.466 0.534
D52.9 Folate deficiency anaemia, unspecified
0.000 0.467 0.532
E67 Other hyperalimentation
0.000 0.468 0.532
E68 Sequelae of hyperalimentation
0.000 0.468 0.532
D80 Immunodeficiency with predominantly antibody defects
0.000 0.468 0.532
B37.0 Candidal stomatitis
0.000 0.469 0.531
H03 Disorders of eyelid in diseases classified elsewhere
0.000 0.469 0.530
H53.8 Other visual disturbances
0.000 0.472 0.528
E65 Localised adiposity
0.000 0.473 0.527
A30-A49 Other bacterial diseases
0.000 0.473 0.527
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.474 0.526
E80.6 Other disorders of bilirubin metabolism
0.000 0.474 0.526
E80.5 Crigler-Najjar syndrome
0.000 0.474 0.526
E80.3 Defects of catalase and peroxydase
0.000 0.474 0.526
E80.1 Porphyria cutanea tarda
0.000 0.474 0.526
E80.0 Hereditary erythropoietic porphyria
0.000 0.474 0.526
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.474 0.526
L27.1 Localised skin eruption due to drugs and medicaments
0.000 0.476 0.524
B65-B83 Helminthiases
0.000 0.478 0.522
H65 Nonsuppurative otitis media
0.000 0.478 0.522
B85-B89 Pediculosis, acariasis and other infestations
0.000 0.479 0.521
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.000 0.479 0.521
A75-A79 Rickettsioses
0.000 0.479 0.521
A70-A74 Other diseases caused by chlamydiae
0.000 0.479 0.521
A65-A69 Other spirochaetal diseases
0.000 0.479 0.521
A20-A28 Certain zoonotic bacterial diseases
0.000 0.479 0.521
A15-A19 Tuberculosis
0.000 0.479 0.521
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.480 0.520
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.480 0.520
D51.2 Transcobalamin II deficiency
0.000 0.480 0.520
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.480 0.520
B99-B99 Other infectious diseases
0.000 0.480 0.520
H04.9 Disorder of lachrymal system, unspecified
0.000 0.481 0.518
H04.8 Other disorders of lachrymal system
0.000 0.481 0.518
H04.6 Other changes in lachrymal passages
0.000 0.481 0.518
H04.0 Dacryoadenitis
0.000 0.481 0.518
D61.8 Other specified aplastic anaemias
0.000 0.482 0.518
D61.3 Idiopathic aplastic anaemia
0.000 0.482 0.518
D61.2 Aplastic anaemia due to other external agents
0.000 0.482 0.518
D61.1 Drug-induced aplastic anaemia
0.000 0.482 0.518
D61.0 Constitutional aplastic anaemia
0.000 0.482 0.518
H33 Retinal detachments and breaks
0.000 0.483 0.517
J12 Viral pneumonia, not elsewhere classified
0.000 0.483 0.517
H34 Retinal vascular occlusions
0.000 0.483 0.517
J33.0 Polyp of nasal cavity
0.000 0.483 0.517
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.000 0.485 0.515
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
L41.9 Parapsoriasis, unspecified
0.000 0.486 0.514
L41.8 Other parapsoriasis
0.000 0.486 0.514
L41.5 Retiform parapsoriasis
0.000 0.486 0.514
L41.4 Large plaque parapsoriasis
0.000 0.486 0.514
L41.3 Small plaque parapsoriasis
0.000 0.486 0.514
L41.2 Lymphomatoid papulosis
0.000 0.486 0.514
L41.1 Pityriasis lichenoides chronica
0.000 0.486 0.514
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.486 0.514
L44.9 Papulosquamous disorder, unspecified
0.000 0.486 0.514
L44.8 Other specified papulosquamous disorders
0.000 0.486 0.514
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.486 0.514
L44.3 Lichen ruber moniliformis
0.000 0.486 0.514
L44.2 Lichen striatus
0.000 0.486 0.514
L44.1 Lichen nitidus
0.000 0.486 0.514
L44.0 Pityriasis rubra pilaris
0.000 0.486 0.514
L13 Other bullous disorders
0.000 0.486 0.514
L12 Pemphigoid
0.000 0.486 0.514
L11 Other acantholytic disorders
0.000 0.486 0.514
L10 Pemphigus
0.000 0.486 0.514
L14 Bullous disorders in diseases classified elsewhere
0.000 0.486 0.514
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.488 0.512
M06.18 Adult-onset Still's disease (Other)
0.000 0.488 0.512
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.488 0.512
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.488 0.512
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.488 0.512
M06.14 Adult-onset Still's disease (Hand)
0.000 0.488 0.512
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.488 0.512
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.488 0.512
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.488 0.512
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.488 0.512
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.488 0.512
M06.28 Rheumatoid bursitis (Other)
0.000 0.488 0.512
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.488 0.512
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.488 0.512
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.488 0.512
M06.24 Rheumatoid bursitis (Hand)
0.000 0.488 0.512
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.488 0.512
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.488 0.512
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.488 0.512

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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