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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs115764752
log Bayes Factor = 0.162609
Chromosome 1   position 171,747,206  (GRCh37) Explore rs115764752 on Ensembl!
Variant rs115764752 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E11.9 Without complications
0.000 0.689 0.311
E11 Non-insulin-dependent diabetes mellitus
0.000 0.693 0.307
E10-E14 Diabetes mellitus
0.000 0.701 0.299
E14 Unspecified diabetes mellitus
0.000 0.704 0.296
E14.9 Without complications
0.000 0.704 0.296
E11.4 With neurological complications
0.000 0.741 0.259
E11.3 With ophthalmic complications
0.000 0.751 0.249
E10 Insulin-dependent diabetes mellitus
0.000 0.769 0.231
E11.8 With unspecified complications
0.000 0.780 0.220
E11.7 With multiple complications
0.000 0.780 0.220
E11.6 With other specified complications
0.000 0.780 0.220
E11.2 With renal complications
0.000 0.780 0.220
E11.1 With ketoacidosis
0.000 0.780 0.220
E11.0 With coma
0.000 0.780 0.220
E13 Other specified diabetes mellitus
0.000 0.786 0.214
E12 Malnutrition-related diabetes mellitus
0.000 0.786 0.214
E14.8 With unspecified complications
0.000 0.788 0.212
E14.7 With multiple complications
0.000 0.788 0.212
E14.6 With other specified complications
0.000 0.788 0.212
E14.5 With peripheral circulatory complications
0.000 0.788 0.212
E14.4 With neurological complications
0.000 0.788 0.212
E14.3 With ophthalmic complications
0.000 0.788 0.212
E14.2 Withrenal complications
0.000 0.788 0.212
E14.1 With ketoacidosis
0.000 0.788 0.212
E14.0 With coma
0.000 0.788 0.212
E11.5 With peripheral circulatory complications
0.000 0.789 0.211
E10.3 With ophthalmic complications
0.000 0.820 0.180
E10.9 Without complications
0.000 0.832 0.168
E10.8 With unspecified complications
0.000 0.834 0.165
E10.7 With multiple complications
0.000 0.834 0.165
E10.6 With other specified complications
0.000 0.834 0.165
E10.5 With peripheral circulatory complications
0.000 0.834 0.165
E10.4 With neurological complications
0.000 0.834 0.165
E10.2 With renal complications
0.000 0.834 0.165
E10.1 With ketoacidosis
0.000 0.834 0.165
E10.0 With coma
0.000 0.834 0.165
E12.9 Without complications
0.000 0.846 0.154
E12.8 With unspecified complications
0.000 0.846 0.154
E12.7 With multiple complications
0.000 0.846 0.154
E12.6 With other specified complications
0.000 0.846 0.154
E12.5 With peripheral circulatory complications
0.000 0.846 0.154
E12.4 With neurological complications
0.000 0.846 0.154
E12.3 With ophthalmic complications
0.000 0.846 0.154
E12.2 With renal complications
0.000 0.846 0.154
E12.1 With ketoacidosis
0.000 0.846 0.154
E12.0 With coma
0.000 0.846 0.154
E13.9 Without complications
0.000 0.846 0.154
E13.8 With unspecified complications
0.000 0.846 0.154
E13.7 With multiple complications
0.000 0.846 0.154
E13.6 With other specified complications
0.000 0.846 0.154
E13.5 With peripheral circulatory complications
0.000 0.846 0.154
E13.4 With neurological complications
0.000 0.846 0.154
E13.3 With ophthalmic complications
0.000 0.846 0.154
E13.2 With renal complications
0.000 0.846 0.154
E13.1 With ketoacidosis
0.000 0.846 0.154
E13.0 With coma
0.000 0.846 0.154
Chapter IV Endocrine, nutritional and metabolic diseases
0.001 0.847 0.153
E65-E68 Obesity and other hyperalimentation
0.000 0.850 0.150
E66 Obesity
0.000 0.851 0.149
E66.9 Obesity, unspecified
0.000 0.851 0.149
E66.8 Other obesity
0.000 0.884 0.116
E40-E46 Malnutrition
0.001 0.890 0.110
E67 Other hyperalimentation
0.000 0.892 0.108
E68 Sequelae of hyperalimentation
0.000 0.892 0.108
E65 Localised adiposity
0.000 0.892 0.108
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.893 0.107
E66.1 Drug-induced obesity
0.000 0.893 0.107
E66.0 Obesity due to excess calories
0.000 0.893 0.107
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.001 0.893 0.106
E50-E64 Other nutritional deficiencies
0.001 0.895 0.105
E00-E07 Disorders of thyroid gland
0.000 0.913 0.087
E20-E35 Disorders of other endocrine glands
0.001 0.916 0.083
E44 Protein-energy malnutrition of moderate and mild degree
0.001 0.921 0.079
E46 Unspecified protein-energy malnutrition
0.001 0.921 0.079
E45 Retarded development following protein-energy malnutrition
0.001 0.921 0.079
E43 Unspecified severe protein-energy malnutrition
0.001 0.921 0.079
E42 Marasmic kwashiorkor
0.001 0.921 0.079
E41 Nutritional marasmus
0.001 0.921 0.079
E40 Kwashiorkor
0.001 0.921 0.079
E67.8 Other specified hyperalimentation
0.000 0.922 0.077
E67.3 Hypervitaminosis D
0.000 0.922 0.077
E67.2 Megavitamin-B6 syndrome
0.000 0.922 0.077
E67.1 Hypercarotenaemia
0.000 0.922 0.077
E67.0 Hypervitaminosis A
0.000 0.922 0.077
E55 Vitamin D deficiency
0.000 0.922 0.077
E15 Nondiabetic hypoglycaemic coma
0.001 0.923 0.076
E64 Sequelae of malnutrition and other nutritional deficiencies
0.001 0.924 0.075
E63 Other nutritional deficiencies
0.001 0.924 0.075
E61 Deficiency of other nutrient elements
0.001 0.924 0.075
E56 Other vitamin deficiencies
0.001 0.924 0.075
E51 Thiamine deficiency
0.001 0.924 0.075
E50 Vitamin A deficiency
0.001 0.924 0.075
E60 Dietary zinc deficiency
0.001 0.924 0.075
E59 Dietary selenium deficiency
0.001 0.924 0.075
E58 Dietary calcium deficiency
0.001 0.924 0.075
E54 Ascorbic acid deficiency
0.001 0.924 0.075
E52 Niacin deficiency [pellagra]
0.001 0.924 0.075
E16 Other disorders of pancreatic internal secretion
0.000 0.926 0.073
E53 Deficiency of other B group vitamins
0.001 0.932 0.068
E04 Other non-toxic goitre
0.000 0.935 0.065
E06 Thyroiditis
0.000 0.937 0.062
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.937 0.062
E00 Congenital iodine-deficiency syndrome
0.000 0.937 0.062
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.937 0.062
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.937 0.062
E23 Hypofunction and other disorders of pituitary gland
0.001 0.939 0.060
E35 Disorders of endocrine glands in diseases classified elsewhere
0.001 0.939 0.060
E34 Other endocrine disorders
0.001 0.939 0.060
E32 Diseases of thymus
0.001 0.939 0.060
E31 Polyglandular dysfunction
0.001 0.939 0.060
E30 Disorders of puberty, not elsewhere classified
0.001 0.939 0.060
E29 Testicular dysfunction
0.001 0.939 0.060
E27 Other disorders of adrenal gland
0.001 0.939 0.060
E26 Hyperaldosteronism
0.001 0.939 0.060
E25 Adrenogenital disorders
0.001 0.939 0.060
E24 Cushing's syndrome
0.001 0.939 0.060
E22 Hyperfunction of pituitary gland
0.001 0.939 0.060
E20 Hypoparathyroidism
0.001 0.939 0.060
E55.9 Vitamin D deficiency, unspecified
0.000 0.942 0.057
E07 Other disorders of thyroid
0.000 0.943 0.057
E44.1 Mild protein-energy malnutrition
0.001 0.943 0.057
E44.0 Moderate protein-energy malnutrition
0.001 0.943 0.057
E55.0 Rickets, active
0.000 0.944 0.055
E50.9 Vitamin A deficiency, unspecified
0.001 0.945 0.054
E50.8 Other manifestations of vitamin A deficiency
0.001 0.945 0.054
E50.7 Other ocular manifestations of vitamin A deficiency
0.001 0.945 0.054
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.001 0.945 0.054
E50.5 Vitamin A deficiency with night blindness
0.001 0.945 0.054
E50.4 Vitamin A deficiency with keratomalacia
0.001 0.945 0.054
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.001 0.945 0.054
E50.2 Vitamin A deficiency with corneal xerosis
0.001 0.945 0.054
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.001 0.945 0.054
E50.0 Vitamin A deficiency with conjunctival xerosis
0.001 0.945 0.054
E51.9 Thiamine deficiency, unspecified
0.001 0.945 0.054
E51.8 Other manifestations of thiamine deficiency
0.001 0.945 0.054
E51.2 Wernicke's encephalopathy
0.001 0.945 0.054
E51.1 Beriberi
0.001 0.945 0.054
E56.9 Vitamin deficiency, unspecified
0.001 0.945 0.054
E56.8 Deficiency of other vitamins
0.001 0.945 0.054
E56.1 Deficiency of vitamin K
0.001 0.945 0.054
E56.0 Deficiency of vitamin E
0.001 0.945 0.054
E61.9 Deficiency of nutrient element, unspecified
0.001 0.945 0.054
E61.8 Deficiency of other specified nutrient elements
0.001 0.945 0.054
E61.7 Deficiency of multiple nutrient elements
0.001 0.945 0.054
E61.6 Vanadium deficiency
0.001 0.945 0.054
E61.5 Molybdenum deficiency
0.001 0.945 0.054
E61.4 Chromium deficiency
0.001 0.945 0.054
E61.3 Manganese deficiency
0.001 0.945 0.054
E61.2 Magnesium deficiency
0.001 0.945 0.054
E61.1 Iron deficiency
0.001 0.945 0.054
E61.0 Copper deficiency
0.001 0.945 0.054
E63.9 Nutritional deficiency, unspecified
0.001 0.945 0.054
E63.8 Other specified nutritional deficiencies
0.001 0.945 0.054
E63.1 Imbalance of constituents of food intake
0.001 0.945 0.054
E63.0 Essential fatty acid [EFA] deficiency
0.001 0.945 0.054
E64.9 Sequelae of unspecified nutritional deficiency
0.001 0.945 0.054
E64.8 Sequelae of other nutritional deficiencies
0.001 0.945 0.054
E64.3 Sequelae of rickets
0.001 0.945 0.054
E64.2 Sequelae of vitamin C deficiency
0.001 0.945 0.054
E64.1 Sequelae of vitamin A deficiency
0.001 0.945 0.054
E64.0 Sequelae of protein-energy malnutrition
0.001 0.945 0.054
E28 Ovarian dysfunction
0.001 0.946 0.053
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.947 0.053
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.947 0.053
E16.4 Abnormal secretion of gastrin
0.000 0.947 0.053
E16.3 Increased secretion of glucagon
0.000 0.947 0.053
E16.1 Other hypoglycaemia
0.000 0.947 0.053
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.947 0.053
E70-E90 Metabolic disorders
0.000 0.950 0.050
E05.9 Thyrotoxicosis, unspecified
0.000 0.950 0.050
E16.2 Hypoglycaemia, unspecified
0.000 0.950 0.049
E53.9 Vitamin B deficiency, unspecified
0.001 0.951 0.049
E53.1 Pyridoxine deficiency
0.001 0.951 0.049
E53.0 Riboflavin deficiency
0.001 0.951 0.049
E04.2 Non-toxic multinodular goitre
0.000 0.952 0.048
E04.9 Non-toxic goitre, unspecified
0.000 0.952 0.048
E04.8 Other specified non-toxic goitre
0.000 0.953 0.047
E04.1 Non-toxic single thyroid nodule
0.000 0.953 0.047
E04.0 Non-toxic diffuse goitre
0.000 0.953 0.047
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.001 0.955 0.044
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.955 0.045
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.955 0.045
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.955 0.045
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.955 0.045
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.955 0.045
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.955 0.045
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.955 0.045
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.955 0.045
E06.9 Thyroiditis, unspecified
0.000 0.955 0.045
E06.5 Other chronic thyroiditis
0.000 0.955 0.045
E06.4 Drug-induced thyroiditis
0.000 0.955 0.045
E06.3 Autoimmune thyroiditis
0.000 0.955 0.045
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.955 0.045
E06.1 Subacute thyroiditis
0.000 0.955 0.045
E06.0 Acute thyroiditis
0.000 0.955 0.045
E05.8 Other thyrotoxicosis
0.000 0.955 0.045
E05.5 Thyroid crisis or storm
0.000 0.955 0.045
E05.4 Thyrotoxicosis factitia
0.000 0.955 0.045
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.955 0.045
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.955 0.045
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.955 0.045
E23.0 Hypopituitarism
0.001 0.956 0.044
E23.7 Disorder of pituitary gland, unspecified
0.001 0.956 0.043
E23.6 Other disorders of pituitary gland
0.001 0.956 0.043
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.001 0.956 0.043
E23.2 Diabetes insipidus
0.001 0.956 0.043
E23.1 Drug-induced hypopituitarism
0.001 0.956 0.043
E20.9 Hypoparathyroidism, unspecified
0.001 0.956 0.043
E20.8 Other hypoparathyroidism
0.001 0.956 0.043
E20.1 Pseudohypoparathyroidism
0.001 0.956 0.043
E20.0 Idiopathic hypoparathyroidism
0.001 0.956 0.043
E22.9 Hyperfunction of pituitary gland, unspecified
0.001 0.956 0.043
E22.8 Other hyperfunction of pituitary gland
0.001 0.956 0.043
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.001 0.956 0.043
E22.1 Hyperprolactinaemia
0.001 0.956 0.043
E22.0 Acromegaly and pituitary gigantism
0.001 0.956 0.043
E24.9 Cushing's syndrome, unspecified
0.001 0.956 0.043
E24.8 Other Cushing's syndrome
0.001 0.956 0.043
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.001 0.956 0.043
E24.3 Ectopic ACTH syndrome
0.001 0.956 0.043
E24.2 Drug-induced Cushing's syndrome
0.001 0.956 0.043
E24.1 Nelson's syndrome
0.001 0.956 0.043
E24.0 Pituitary-dependent Cushing's disease
0.001 0.956 0.043
E25.9 Adrenogenital disorder, unspecified
0.001 0.956 0.043
E25.8 Other adrenogenital disorders
0.001 0.956 0.043
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.001 0.956 0.043
E26.9 Hyperaldosteronism, unspecified
0.001 0.956 0.043
E26.8 Other hyperaldosteronism
0.001 0.956 0.043
E26.1 Secondary hyperaldosteronism
0.001 0.956 0.043
E26.0 Primary hyperaldosteronism
0.001 0.956 0.043
E27.9 Disorder of adrenal gland, unspecified
0.001 0.956 0.043
E27.8 Other specified disorders of adrenal gland
0.001 0.956 0.043
E27.5 Adrenomedullary hyperfunction
0.001 0.956 0.043
E27.4 Other and unspecified adrenocortical insufficiency
0.001 0.956 0.043
E27.3 Drug-induced adrenocortical insufficiency
0.001 0.956 0.043
E27.2 Addisonian crisis
0.001 0.956 0.043
E27.1 Primary adrenocortical insufficiency
0.001 0.956 0.043
E27.0 Other adrenocortical overactivity
0.001 0.956 0.043
E29.9 Testicular dysfunction, unspecified
0.001 0.956 0.043
E29.8 Other testicular dysfunction
0.001 0.956 0.043
E29.1 Testicular hypofunction
0.001 0.956 0.043
E29.0 Testicular hyperfunction
0.001 0.956 0.043
E30.9 Disorder of puberty, unspecified
0.001 0.956 0.043
E30.8 Other disorders of puberty
0.001 0.956 0.043
E30.1 Precocious puberty
0.001 0.956 0.043
E30.0 Delayed puberty
0.001 0.956 0.043
E31.9 Polyglandular dysfunction, unspecified
0.001 0.956 0.043
E31.8 Other polyglandular dysfunction
0.001 0.956 0.043
E31.1 Polyglandular hyperfunction
0.001 0.956 0.043
E31.0 Autoimmune polyglandular failure
0.001 0.956 0.043
E32.9 Disease of thymus, unspecified
0.001 0.956 0.043
E32.8 Other diseases of thymus
0.001 0.956 0.043
E32.1 Abscess of thymus
0.001 0.956 0.043
E32.0 Persistent hyperplasia of thymus
0.001 0.956 0.043
E34.9 Endocrine disorder, unspecified
0.001 0.956 0.043
E34.8 Other specified endocrine disorders
0.001 0.956 0.043
E34.5 Androgen resistance syndrome
0.001 0.956 0.043
E34.4 Constitutional tall stature
0.001 0.956 0.043
E34.3 Short stature, not elsewhere classified
0.001 0.956 0.043
E34.2 Ectopic hormone secretion, not elsewhere classified
0.001 0.956 0.043
E34.1 Other hypersecretion of intestinal hormones
0.001 0.956 0.043
E34.0 Carcinoid syndrome
0.001 0.956 0.043
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.001 0.956 0.043
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.001 0.956 0.043
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.001 0.956 0.043
E03 Other hypothyroidism
0.000 0.957 0.042
E53.8 Deficiency of other specified B group vitamins
0.001 0.958 0.042
E07.8 Other specified disorders of thyroid
0.000 0.959 0.041
E07.1 Dyshormogenetic goitre
0.000 0.959 0.041
E07.0 Hypersecretion of calcitonin
0.000 0.959 0.041
E28.9 Ovarian dysfunction, unspecified
0.001 0.961 0.038
E28.8 Other ovarian dysfunction
0.001 0.961 0.038
E28.3 Primary ovarian failure
0.001 0.961 0.038
E28.1 Androgen excess
0.001 0.961 0.038
E28.0 Oestrogen excess
0.001 0.961 0.038
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.961 0.038
E07.9 Disorder of thyroid, unspecified
0.001 0.964 0.036
E86 Volume depletion
0.000 0.964 0.036
E85 Amyloidosis
0.000 0.964 0.036
E84 Cystic fibrosis
0.000 0.964 0.036
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.964 0.036
E79 Disorders of purine and pyrimidine metabolism
0.000 0.964 0.036
E77 Disorders of glycoprotein metabolism
0.000 0.964 0.036
E76 Disorders of glycosaminoglycan metabolism
0.000 0.964 0.036
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.964 0.036
E74 Other disorders of carbohydrate metabolism
0.000 0.964 0.036
E73 Lactose intolerance
0.000 0.964 0.036
E72 Other disorders of amino-acid metabolism
0.000 0.964 0.036
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.964 0.036
E70 Disorders of aromatic amino-acid metabolism
0.000 0.964 0.036
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.964 0.036
E88 Other metabolic disorders
0.000 0.965 0.034
E83 Disorders of mineral metabolism
0.000 0.966 0.033
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.967 0.033
E21.5 Disorder of parathyroid gland, unspecified
0.001 0.967 0.032
E21.4 Other specified disorders of parathyroid gland
0.001 0.967 0.032
E21.2 Other hyperparathyroidism
0.001 0.967 0.032
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.001 0.967 0.032
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.967 0.033
E28.2 Polycystic ovarian syndrome
0.001 0.967 0.032
E03.8 Other specified hypothyroidism
0.000 0.969 0.031
E03.5 Myxoedema coma
0.000 0.969 0.031
E03.4 Atrophy of thyroid (acquired)
0.000 0.969 0.031
E03.3 Postinfectious hypothyroidism
0.000 0.969 0.031
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.969 0.031
E03.1 Congenital hypothyroidism without goitre
0.000 0.969 0.031
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.969 0.031
E21.3 Hyperparathyroidism, unspecified
0.001 0.971 0.028
E83.1 Disorders of iron metabolism
0.000 0.972 0.028
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.974 0.026
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.974 0.026
E70.3 Albinism
0.000 0.974 0.026
E70.2 Disorders of tyrosine metabolism
0.000 0.974 0.026
E70.1 Other hyperphenylalaninaemias
0.000 0.974 0.026
E70.0 Classical phenylketonuria
0.000 0.974 0.026
E71.3 Disorders of fatty-acid metabolism
0.000 0.974 0.026
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.974 0.026
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.974 0.026
E71.0 Maple-syrup-urine disease
0.000 0.974 0.026
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.974 0.026
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.974 0.026
E72.5 Disorders of glycine metabolism
0.000 0.974 0.026
E72.4 Disorders of ornithine metabolism
0.000 0.974 0.026
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.974 0.026
E72.2 Disorders of urea cycle metabolism
0.000 0.974 0.026
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.974 0.026
E72.0 Disorders of amino-acid transport
0.000 0.974 0.026
E73.9 Lactose intolerance, unspecified
0.000 0.974 0.026
E73.8 Other lactose intolerance
0.000 0.974 0.026
E73.1 Secondary lactase deficiency
0.000 0.974 0.026
E73.0 Congenital lactase deficiency
0.000 0.974 0.026
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.974 0.026
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.974 0.026
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.974 0.026
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.974 0.026
E74.2 Disorders of galactose metabolism
0.000 0.974 0.026
E74.1 Disorders of fructose metabolism
0.000 0.974 0.026
E74.0 Glycogen storage disease
0.000 0.974 0.026
E75.6 Lipid storage disorder, unspecified
0.000 0.974 0.026
E75.5 Other lipid storage disorders
0.000 0.974 0.026
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.974 0.026
E75.3 Sphingolipidosis, unspecified
0.000 0.974 0.026
E75.2 Other sphingolipidosis
0.000 0.974 0.026
E75.1 Other gangliosidosis
0.000 0.974 0.026
E75.0 GM2 gangliosidosis
0.000 0.974 0.026
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.974 0.026
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.974 0.026
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.974 0.026
E76.2 Other mucopolysaccharidoses
0.000 0.974 0.026
E76.1 Mucopolysaccharidosis, type II
0.000 0.974 0.026
E76.0 Mucopolysaccharidosis, type I
0.000 0.974 0.026
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.974 0.026
E77.8 Other disorders of glycoprotein metabolism
0.000 0.974 0.026
E77.1 Defects in glycoprotein degradation
0.000 0.974 0.026
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.974 0.026
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.974 0.026
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.974 0.026
E79.1 Lesch-Nyhan syndrome
0.000 0.974 0.026
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.974 0.026
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.974 0.026
E80.6 Other disorders of bilirubin metabolism
0.000 0.974 0.026
E80.5 Crigler-Najjar syndrome
0.000 0.974 0.026
E80.4 Gilbert's syndrome
0.000 0.974 0.026
E80.3 Defects of catalase and peroxydase
0.000 0.974 0.026
E80.2 Other porphyria
0.000 0.974 0.026
E80.1 Porphyria cutanea tarda
0.000 0.974 0.026
E80.0 Hereditary erythropoietic porphyria
0.000 0.974 0.026
E84.9 Cystic fibrosis, unspecified
0.000 0.974 0.026
E84.8 Cystic fibrosis with other manifestations
0.000 0.974 0.026
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.974 0.026
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.974 0.026
E85.9 Amyloidosis, unspecified
0.000 0.974 0.026
E85.8 Other amyloidosis
0.000 0.974 0.026
E85.4 Organ-limited amyloidosis
0.000 0.974 0.026
E85.3 Secondary systemic amyloidosis
0.000 0.974 0.026
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.974 0.026
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.974 0.026
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.974 0.026
E78.5 Hyperlipidaemia, unspecified
0.000 0.974 0.026
E88.9 Metabolic disorder, unspecified
0.000 0.975 0.025
E88.8 Other specified metabolic disorders
0.000 0.975 0.025
E88.3 Tumour lysis syndrome
0.000 0.975 0.025
E88.2 Lipomatosis, not elsewhere classified
0.000 0.975 0.025
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.975 0.025
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.976 0.024
E83.8 Other disorders of mineral metabolism
0.000 0.976 0.024
E83.3 Disorders of phosphorus metabolism
0.000 0.976 0.024
E83.2 Disorders of zinc metabolism
0.000 0.976 0.024
E83.0 Disorders of copper metabolism
0.000 0.976 0.024
E21.0 Primary hyperparathyroidism
0.001 0.976 0.023
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.976 0.024
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.976 0.024
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.976 0.024
E89.5 Postprocedural testicular hypofunction
0.000 0.976 0.024
E89.4 Postprocedural ovarian failure
0.000 0.976 0.024
E89.3 Postprocedural hypopituitarism
0.000 0.976 0.024
E89.2 Postprocedural hypoparathyroidism
0.000 0.976 0.024
E89.1 Postprocedural hypoinsulinaemia
0.000 0.976 0.024
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.976 0.023
E78.8 Other disorders of lipoprotein metabolism
0.000 0.976 0.023
E78.6 Lipoprotein deficiency
0.000 0.976 0.023
E78.4 Other hyperlipidaemia
0.000 0.976 0.023
E78.3 Hyperchylomicronaemia
0.000 0.976 0.023
E78.2 Mixed hyperlipidaemia
0.000 0.976 0.023
E78.1 Pure hyperglyceridaemia
0.000 0.976 0.023
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.977 0.023
E83.4 Disorders of magnesium metabolism
0.000 0.979 0.021
E89.0 Postprocedural hypothyroidism
0.000 0.979 0.020
E83.5 Disorders of calcium metabolism
0.000 0.982 0.018
E78.0 Pure hypercholesterolaemia
0.000 0.982 0.018
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.988 0.012
E03.9 Hypothyroidism, unspecified
0.000 0.989 0.011
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.009 0.991 0.000
D25 Leiomyoma of uterus
0.009 0.991 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.000 0.991 0.008
E87.4 Mixed disorder of acid-base balance
0.000 0.991 0.008
E87.0 Hyperosmolality and hypernatraemia
0.000 0.991 0.008
E87.2 Acidosis
0.000 0.991 0.008
D25.1 Intramural leiomyoma of uterus
0.009 0.991 0.000
Y52 Agents primarily affecting the cardiovascular system
0.009 0.991 0.000
D10-D36 Benign neoplasms
0.009 0.991 0.000
D25.2 Subserosal leiomyoma of uterus
0.008 0.992 0.000
Y43 Primarily systemic agents
0.008 0.992 0.000
D25.0 Submucous leiomyoma of uterus
0.008 0.992 0.000
D23 Other benign neoplasms of skin
0.008 0.992 0.000
E87.7 Fluid overload
0.000 0.992 0.008
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.008 0.992 0.000
D27 Benign neoplasm of ovary
0.008 0.992 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.008 0.992 0.000
Y43.3 Other antineoplastic drugs
0.008 0.992 0.000
D10 Benign neoplasm of mouth and pharynx
0.008 0.992 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.008 0.992 0.000
D23.5 Skin of trunk
0.008 0.992 0.000
E87.5 Hyperkalaemia
0.000 0.992 0.007
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.008 0.992 0.000
D10.3 Other and unspecified parts of mouth
0.007 0.993 0.000
D23.9 Skin, unspecified
0.007 0.993 0.000
O60-O75 Complications of labour and delivery
0.007 0.993 0.000
Chapter XX External causes of morbidity and mortality
0.007 0.993 0.000
D26 Other benign neoplasms of uterus
0.007 0.993 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.007 0.993 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.007 0.993 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.007 0.993 0.000
Y54.3 Benzothiadiazine derivatives
0.007 0.993 0.000
D22 Melanocytic naevi
0.007 0.993 0.000
D32 Benign neoplasm of meninges
0.007 0.993 0.000
D22.7 Melanocytic naevi of lower limb, including hip
0.007 0.993 0.000
E87.3 Alkalosis
0.001 0.993 0.007
D33 Benign neoplasm of brain and other parts of central nervous system
0.007 0.993 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.007 0.993 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.007 0.993 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.007 0.993 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.007 0.993 0.000
Y59 Other and unspecified vaccines and biological substances
0.007 0.993 0.000
Y58 Bacterial vaccines
0.007 0.993 0.000
Y57 Other and unspecified drugs and medicaments
0.007 0.993 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.007 0.993 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.007 0.993 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.007 0.993 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.007 0.993 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.007 0.993 0.000
Y48 Anaesthetics and therapeutic gases
0.007 0.993 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.007 0.993 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.007 0.993 0.000
Y44 Agents primarily affecting blood constituents
0.007 0.993 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.007 0.993 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.007 0.993 0.000
Y95 Nosocomial condition
0.007 0.993 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.007 0.993 0.000
Y45.0 Opioids and related analgesics
0.007 0.993 0.000
F32 Depressive episode
0.007 0.993 0.000
Y42.5 Other oestrogens and progestogens
0.007 0.993 0.000
Y40 Systemic antibiotics
0.007 0.993 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.007 0.993 0.000
D23.4 Skin of scalp and neck
0.007 0.993 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.007 0.993 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.000 0.993 0.006
D34 Benign neoplasm of thyroid gland
0.006 0.993 0.000
O20.9 Haemorrhage in early pregnancy, unspecified
0.006 0.993 0.000
D26.1 Corpus uteri
0.006 0.993 0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system
0.006 0.994 0.000
Y52.8 Antivaricose drugs, including sclerosing agents
0.006 0.994 0.000
Y52.7 Peripheral vasodilators
0.006 0.994 0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.006 0.994 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.006 0.994 0.000
Y52.1 Calcium-channel blockers
0.006 0.994 0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action
0.006 0.994 0.000
D31 Benign neoplasm of eye and adnexa
0.006 0.994 0.000
D30 Benign neoplasm of urinary organs
0.006 0.994 0.000
D29 Benign neoplasm of male genital organs
0.006 0.994 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.006 0.994 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.006 0.994 0.000
D19 Benign neoplasm of mesothelial tissue
0.006 0.994 0.000
D16 Benign neoplasm of bone and articular cartilage
0.006 0.994 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.006 0.994 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.006 0.994 0.000
D11 Benign neoplasm of major salivary glands
0.006 0.994 0.000
Y43.9 Primarily systemic agent, unspecified
0.006 0.994 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.006 0.994 0.000
Y43.6 Enzymes, not elsewhere classified
0.006 0.994 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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