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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs11598874
log Bayes Factor = 10.4305
Chromosome 10   position 39,006,198  (GRCh37) Explore rs11598874 on Ensembl!
Variant rs11598874 is part of Cluster X0264

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
0.999 0.001 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.999 0.001 0.000
Chapter II Neoplasms
0.998 0.002 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.998 0.002 0.000
Chapter XXI Factors influencing health status and contact with health services
0.996 0.004 0.000
E11 Non-insulin-dependent diabetes mellitus
0.994 0.006 0.000
C15-C26 Malignant neoplasms of digestive organs
0.993 0.007 0.000
C64-C68 Malignant neoplasms of urinary tract
0.992 0.008 0.000
Chapter IX Diseases of the circulatory system
0.991 0.009 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.989 0.011 0.000
Z46.6 Fitting and adjustment of urinary device
0.988 0.012 0.000
Z46 Fitting and adjustment of other devices
0.988 0.012 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.987 0.013 0.000
C18 Malignant neoplasm of colon
0.986 0.014 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.985 0.015 0.000
Z60 Problems related to social environment
0.982 0.018 0.000
Z60.2 Living alone
0.977 0.023 0.000
C67 Malignant neoplasm of bladder
0.962 0.038 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.961 0.039 0.000
E11.4 With neurological complications
0.960 0.040 0.000
C18.0 Caecum
0.960 0.040 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.960 0.040 0.000
I20-I25 Ischaemic heart diseases
0.959 0.041 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.953 0.047 0.000
S60-S69 Injuries to the wrist and hand
0.951 0.049 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.950 0.050 0.000
E10.9 Without complications
0.946 0.054 0.000
E11.3 With ophthalmic complications
0.946 0.054 0.000
S50-S59 Injuries to the elbow and forearm
0.945 0.055 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.941 0.059 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.931 0.069 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.928 0.072 0.000
E10.3 With ophthalmic complications
0.925 0.075 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.922 0.078 0.000
C18.7 Sigmoid colon
0.922 0.078 0.000
S40-S49 Injuries to the shoulder and upper arm
0.922 0.078 0.000
O26.9 Pregnancy-related condition, unspecified
0.922 0.078 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.919 0.081 0.000
N40 Hyperplasia of prostate
0.912 0.088 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.911 0.089 0.000
N40-N51 Diseases of male genital organs
0.908 0.092 0.000
C15 Malignant neoplasm of oesophagus
0.903 0.097 0.000
I20 Angina pectoris
0.900 0.100 0.000
Chapter XIV Diseases of the genitourinary system
0.900 0.100 0.000
I74 Arterial embolism and thrombosis
0.898 0.102 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.897 0.103 0.000
S20-S29 Injuries to the thorax
0.892 0.108 0.000
E20-E35 Disorders of other endocrine glands
0.891 0.109 0.000
I22 Subsequent myocardial infarction
0.887 0.113 0.000
E10.4 With neurological complications
0.883 0.117 0.000
M19.9 Arthrosis, unspecified
0.877 0.123 0.000
S64 Injury of nerves at wrist and hand level
0.877 0.123 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.876 0.124 0.000
M15-M19 Arthrosis
0.874 0.126 0.000
M19 Other arthrosis
0.873 0.127 0.000
C67.6 Ureteric orifice
0.870 0.130 0.000
E10.1 With ketoacidosis
0.867 0.133 0.000
E16 Other disorders of pancreatic internal secretion
0.866 0.133 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.863 0.137 0.000
Z47 Other orthopaedic follow-up care
0.861 0.139 0.000
I77 Other disorders of arteries and arterioles
0.859 0.141 0.000
I20.9 Angina pectoris, unspecified
0.858 0.142 0.000
Z46.8 Fitting and adjustment of other specified devices
0.858 0.142 0.000
C60-C63 Malignant neoplasms of male genital organs
0.856 0.143 0.000
I70 Atherosclerosis
0.856 0.144 0.000
O85-O92 Complications predominantly related to the puerperium
0.852 0.148 0.000
C18.9 Colon, unspecified
0.851 0.149 0.000
E10.0 With coma
0.850 0.150 0.000
N48 Other disorders of penis
0.849 0.151 0.000
E11.2 With renal complications
0.847 0.153 0.000
M19.92 Arthrosis, unspecified (Upper arm)
0.845 0.155 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.845 0.155 0.000
S20 Superficial injury of thorax
0.842 0.158 0.000
C67.9 Bladder, unspecified
0.842 0.158 0.000
E10.2 With renal complications
0.838 0.162 0.000
M19.97 Arthrosis, unspecified (Ankle and foot)
0.837 0.163 0.000
S90-S99 Injuries to the ankle and foot
0.835 0.165 0.000
C67.5 Bladder neck
0.832 0.168 0.000
O23 Infections of genito-urinary tract in pregnancy
0.831 0.169 0.000
Chapter VII Diseases of the eye and adnexa
0.827 0.173 0.000
E16.2 Hypoglycaemia, unspecified
0.827 0.173 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.826 0.174 0.000
O80-O84 Delivery
0.825 0.175 0.000
I24 Other acute ischaemic heart diseases
0.823 0.177 0.000
I05-I09 Chronic rheumatic heart diseases
0.822 0.178 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.822 0.178 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.821 0.179 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.821 0.179 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.819 0.181 0.000
E65-E68 Obesity and other hyperalimentation
0.818 0.182 0.000
O26.8 Other specified pregnancy-related conditions
0.816 0.184 0.000
Z41 Procedures for purposes other than remedying health state
0.816 0.184 0.000
T87 Complications peculiar to reattachment and amputation
0.815 0.185 0.000
O42 Premature rupture of membranes
0.810 0.190 0.000
C16 Malignant neoplasm of stomach
0.809 0.191 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.808 0.192 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.808 0.192 0.000
E14 Unspecified diabetes mellitus
0.807 0.193 0.000
S50 Superficial injury of forearm
0.806 0.194 0.000
S70-S79 Injuries to the hip and thigh
0.806 0.194 0.000
C65 Malignant neoplasm of renal pelvis
0.806 0.194 0.000
H30-H36 Disorders of choroid and retina
0.804 0.196 0.000
E11.6 With other specified complications
0.804 0.196 0.000
O44 Placenta praevia
0.804 0.196 0.000
M80-M85 Disorders of bone density and structure
0.803 0.197 0.000
N45 Orchitis and epididymitis
0.800 0.200 0.000
E13 Other specified diabetes mellitus
0.799 0.200 0.000
E27 Other disorders of adrenal gland
0.799 0.201 0.000
M19.98 Arthrosis, unspecified (Other)
0.796 0.204 0.000
S42 Fracture of shoulder and upper arm
0.796 0.204 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.795 0.205 0.000
S20.2 Contusion of thorax
0.795 0.205 0.000
C61 Malignant neoplasm of prostate
0.793 0.207 0.000
E10.6 With other specified complications
0.792 0.208 0.000
Chapter I Certain infectious and parasitic diseases
0.790 0.210 0.000
C73 Malignant neoplasm of thyroid gland
0.788 0.212 0.000
S51 Open wound of forearm
0.788 0.212 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.788 0.212 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.786 0.214 0.000
H53-H54 Visual disturbances and blindness
0.785 0.215 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.783 0.217 0.000
Chapter VI Diseases of the nervous system
0.782 0.218 0.000
S52 Fracture of forearm
0.781 0.219 0.000
N42 Other disorders of prostate
0.781 0.219 0.000
E40-E46 Malnutrition
0.777 0.223 0.000
S80-S89 Injuries to the knee and lower leg
0.777 0.223 0.000
Z46.3 Fitting and adjustment of dental prosthetic device
0.777 0.223 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.775 0.225 0.000
E11.8 With unspecified complications
0.775 0.225 0.000
M91-M94 Chondropathies
0.772 0.228 0.000
I10-I15 Hypertensive diseases
0.772 0.228 0.000
Z56 Problems related to employment and unemployment
0.771 0.229 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.771 0.229 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.770 0.230 0.000
O22 Venous complications in pregnancy
0.770 0.230 0.000
T82.3 Mechanical complication of other vascular grafts
0.768 0.232 0.000
C15.4 Middle third of oesophagus
0.766 0.234 0.000
O24 Diabetes mellitus in pregnancy
0.764 0.236 0.000
H36 Retinal disorders in diseases classified elsewhere
0.764 0.236 0.000
I77.1 Stricture of artery
0.763 0.237 0.000
Z57 Occupational exposure to risk-factors
0.760 0.240 0.000
S64.4 Injury of digital nerve of other finger
0.757 0.243 0.000
H54 Blindness and low vision
0.756 0.244 0.000
S62 Fracture at wrist and hand level
0.754 0.246 0.000
S40 Superficial injury of shoulder and upper arm
0.752 0.248 0.000
C21 Malignant neoplasm of anus and anal canal
0.750 0.250 0.000
E10.5 With peripheral circulatory complications
0.750 0.250 0.000
C18.2 Ascending colon
0.749 0.251 0.000
Z44 Fitting and adjustment of external prosthetic device
0.749 0.251 0.000
Z52 Donors of organs and tissues
0.748 0.252 0.000
S69 Other and unspecified injuries of wrist and hand
0.746 0.254 0.000
Z47.9 Orthopaedic follow-up care, unspecified
0.746 0.254 0.000
H35 Other retinal disorders
0.745 0.255 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.744 0.256 0.000
S56 Injury of muscle and tendon at forearm level
0.741 0.259 0.000
N48.6 Balanitis xerotica obliterans
0.740 0.260 0.000
C18.1 Appendix
0.739 0.261 0.000
S65 Injury of blood vessels at wrist and hand level
0.739 0.261 0.000
N48.8 Other specified disorders of penis
0.739 0.261 0.000
E11.0 With coma
0.735 0.265 0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.735 0.265 0.000
M05-M14 Inflammatory polyarthropathies
0.735 0.265 0.000
H36.0 Diabetic retinopathy
0.735 0.265 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.733 0.267 0.000
O60-O75 Complications of labour and delivery
0.732 0.268 0.000
S64.3 Injury of digital nerve of thumb
0.732 0.268 0.000
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device
0.731 0.269 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.731 0.269 0.000
Z54 Convalescence
0.730 0.270 0.000
Chapter VIII Diseases of the ear and mastoid process
0.730 0.270 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.726 0.274 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.725 0.275 0.000
O82 Single delivery by Caesarean section
0.724 0.276 0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.723 0.277 0.000
O26.2 Pregnancy care of habitual aborter
0.722 0.278 0.000
E11.5 With peripheral circulatory complications
0.721 0.278 0.000
C15.5 Lower third of oesophagus
0.720 0.280 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.720 0.280 0.000
I74.5 Embolism and thrombosis of iliac artery
0.719 0.281 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.718 0.282 0.000
S50.0 Contusion of elbow
0.718 0.282 0.000
I95 Hypotension
0.718 0.282 0.000
I12 Hypertensive renal disease
0.718 0.282 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.718 0.282 0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E10.8 With unspecified complications
0.716 0.283 0.000
E10.7 With multiple complications
0.716 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.715 0.284 0.000
T33-T35 Frostbite
0.715 0.285 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.715 0.285 0.000
T00-T07 Injuries involving multiple body regions
0.715 0.285 0.000
O47 False labour
0.715 0.285 0.000
C16.0 Cardia
0.714 0.286 0.000
E11.7 With multiple complications
0.712 0.288 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.712 0.288 0.000
C23 Malignant neoplasm of gallbladder
0.712 0.288 0.000
C17 Malignant neoplasm of small intestine
0.712 0.288 0.000
S42.0 Fracture of clavicle
0.711 0.289 0.000
Z40 Prophylactic surgery
0.711 0.289 0.000
O20 Haemorrhage in early pregnancy
0.711 0.289 0.000
C91 Lymphoid leukaemia
0.711 0.289 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.711 0.289 0.000
I00-I02 Acute rheumatic fever
0.711 0.289 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.711 0.289 0.000
O34.7 Maternal care for abnormality of vulva and perineum
0.710 0.290 0.000
C15.3 Upper third of oesophagus
0.710 0.290 0.000
Z65 Problems related to other psychosocial circumstances
0.709 0.291 0.000
Z64 Problems related to certain psychosocial circumstances
0.709 0.291 0.000
Z62 Other problems related to upbringing
0.709 0.291 0.000
Z61 Problems related to negative life events in childhood
0.709 0.291 0.000
Z59 Problems related to housing and economic circumstances
0.709 0.291 0.000
Z58 Problems related to physical environment
0.709 0.291 0.000
Z55 Problems related to education and literacy
0.709 0.291 0.000
Z46.9 Fitting and adjustment of other unspecified device
0.708 0.292 0.000
Z46.7 Fitting and adjustment of orthopaedic device
0.708 0.292 0.000
Z46.4 Fitting and adjustment of orthodontic device
0.708 0.292 0.000
Z46.1 Fitting and adjustment of hearing aid
0.708 0.292 0.000
Z46.0 Fitting and adjustment of spectacles and contact lenses
0.708 0.292 0.000
S10-S19 Injuries to the neck
0.708 0.292 0.000
S20.3 Other superficial injuries of front wall of thorax
0.708 0.292 0.000
S60 Superficial injury of wrist and hand
0.707 0.292 0.000
C18.8 Overlapping lesion of colon
0.707 0.293 0.000
C18.5 Splenic flexure
0.707 0.293 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.707 0.293 0.000
O29 Complications of anaesthesia during pregnancy
0.706 0.294 0.000
O28 Abnormal findings on antenatal screening of mother
0.706 0.294 0.000
O25 Malnutrition in pregnancy
0.706 0.294 0.000
C67.4 Posterior wall of bladder
0.705 0.295 0.000
Z60.9 Problem related to social environment, unspecified
0.704 0.296 0.000
Z60.8 Other problems related to social environment
0.704 0.296 0.000
Z60.5 Target of perceived adverse discrimination and persecution
0.704 0.296 0.000
Z60.4 Social exclusion and rejection
0.704 0.296 0.000
Z60.3 Acculturation difficulty
0.704 0.296 0.000
Z60.1 Atypical parenting situation
0.704 0.296 0.000
Z60.0 Problems of adjustment to life-cycle transitions
0.704 0.296 0.000
Z45 Adjustment and management of implanted device
0.702 0.297 0.000
S64.1 Injury of median nerve at wrist and hand level
0.702 0.298 0.000
O23.4 Unspecified infection of urinary tract in pregnancy
0.702 0.298 0.000
M15 Polyarthrosis
0.701 0.299 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.701 0.299 0.000
O30 Multiple gestation
0.701 0.299 0.000
G40-G47 Episodic and paroxysmal disorders
0.701 0.299 0.000
C66 Malignant neoplasm of ureter
0.698 0.301 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.695 0.305 0.000
N48.0 Leukoplakia of penis
0.695 0.305 0.000
E66 Obesity
0.695 0.305 0.000
N48.9 Disorder of penis, unspecified
0.694 0.306 0.000
O44.1 Placenta praevia with haemorrhage
0.693 0.306 0.000
S81 Open wound of lower leg
0.693 0.307 0.000
Z46.5 Fitting and adjustment of ileostomy and other intestinal appliances
0.693 0.307 0.000
T87.6 Other and unspecified complications of amputation stump
0.693 0.307 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.692 0.308 0.000
I25 Chronic ischaemic heart disease
0.692 0.308 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.691 0.309 0.000
C67.8 Overlapping lesion of bladder
0.690 0.310 0.000
C67.7 Urachus
0.690 0.310 0.000
C67.3 Anterior wall of bladder
0.690 0.310 0.000
C67.0 Trigone of bladder
0.690 0.310 0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium
0.688 0.312 0.000
O26.6 Liver disorders in pregnancy, childbirth and the puerperium
0.688 0.312 0.000
O26.5 Maternal hypotension syndrome
0.688 0.312 0.000
O26.4 Herpes gestationis
0.688 0.312 0.000
O26.3 Retained intra-uterine contraceptive device in pregnancy
0.688 0.312 0.000
O26.1 Low weight gain in pregnancy
0.688 0.312 0.000
O26.0 Excessive weight gain in pregnancy
0.688 0.312 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.688 0.312 0.000
I23 Certain current complications following acute myocardial infarction
0.688 0.312 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.687 0.313 0.000
I08 Multiple valve diseases
0.687 0.313 0.000
Z63 Other problems related to primary support group, including family circumstances
0.685 0.314 0.000
C15.9 Oesophagus, unspecified
0.684 0.316 0.000
O45 Premature separation of placenta [abruptio placentae]
0.683 0.316 0.000
O33 Maternal care for known or suspected disproportion
0.683 0.316 0.000
O31 Complications specific to multiple gestation
0.683 0.316 0.000
O90 Complications of the puerperium, not elsewhere classified
0.683 0.317 0.000
C67.1 Dome of bladder
0.682 0.318 0.000
T79-T79 Certain early complications of trauma
0.681 0.319 0.000
O40 Polyhydramnios
0.681 0.319 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.681 0.319 0.000
H54.0 Blindness, both eyes
0.680 0.320 0.000
H35.8 Other specified retinal disorders
0.679 0.320 0.000
H90-H95 Other disorders of ear
0.679 0.321 0.000
Z46.2 Fitting and adjustment of other devices related to nervous system and special senses
0.679 0.321 0.000
S29 Other and unspecified injuries of thorax
0.679 0.321 0.000
Z43 Attention to artificial openings
0.679 0.321 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.678 0.322 0.000
S80 Superficial injury of lower leg
0.678 0.322 0.000
S59 Other and unspecified injuries of forearm
0.677 0.323 0.000
S58 Traumatic amputation of forearm
0.677 0.323 0.000
S57 Crushing injury of forearm
0.677 0.323 0.000
S55 Injury of blood vessels at forearm level
0.677 0.323 0.000
S54 Injury of nerves at forearm level
0.677 0.323 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.677 0.323 0.000
H35.9 Retinal disorder, unspecified
0.677 0.323 0.000
H54.4 Blindness, one eye
0.677 0.323 0.000
I72 Other aneurysm
0.677 0.323 0.000
M84 Disorders of continuity of bone
0.676 0.324 0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level
0.676 0.324 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.676 0.324 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.676 0.324 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.676 0.324 0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified
0.674 0.325 0.000
O34.8 Maternal care for other abnormalities of pelvic organs
0.674 0.325 0.000
O34.6 Maternal care for abnormality of vagina
0.674 0.325 0.000
O34.5 Maternal care for other abnormalities of gravid uterus
0.674 0.325 0.000
O34.4 Maternal care for other abnormalities of cervix
0.674 0.325 0.000
O34.3 Maternal care for cervical incompetence
0.674 0.325 0.000
O34.1 Maternal care for tumour of corpus uteri
0.674 0.325 0.000
O34.0 Maternal care for congenital malformation of uterus
0.674 0.325 0.000
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified
0.674 0.326 0.000
E20 Hypoparathyroidism
0.673 0.327 0.000
C88 Malignant immunoproliferative diseases
0.672 0.327 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.672 0.328 0.000
E29 Testicular dysfunction
0.672 0.328 0.000
O87 Venous complications in the puerperium
0.671 0.329 0.000
I20.1 Angina pectoris with documented spasm
0.670 0.330 0.000
S51.9 Open wound of forearm, part unspecified
0.670 0.330 0.000
N50 Other disorders of male genital organs
0.669 0.331 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.666 0.334 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.665 0.335 0.000
C67.2 Lateral wall of bladder
0.664 0.336 0.000
I12.0 Hypertensive renal disease with renal failure
0.664 0.336 0.000
T86 Failure and rejection of transplanted organs and tissues
0.662 0.338 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.662 0.338 0.000
M65-M68 Disorders of synovium and tendon
0.661 0.339 0.000
S41 Open wound of shoulder and upper arm
0.661 0.339 0.000
E15 Nondiabetic hypoglycaemic coma
0.661 0.339 0.000
M85 Other disorders of bone density and structure
0.661 0.339 0.000
S48 Traumatic amputation of shoulder and upper arm
0.661 0.339 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.661 0.339 0.000
S44 Injury of nerves at shoulder and upper arm level
0.661 0.339 0.000
S47 Crushing injury of shoulder and upper arm
0.661 0.339 0.000
M13 Other arthritis
0.660 0.340 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.659 0.341 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.659 0.341 0.000
C20 Malignant neoplasm of rectum
0.659 0.341 0.000
Chapter XX External causes of morbidity and mortality
0.659 0.341 0.000
M40-M43 Deforming dorsopathies
0.659 0.341 0.000
M60-M63 Disorders of muscles
0.658 0.341 0.000
O16 Unspecified maternal hypertension
0.658 0.342 0.000
S50.1 Contusion of other and unspecified parts of forearm
0.658 0.342 0.000
C18.4 Transverse colon
0.657 0.343 0.000
E13.9 Without complications
0.656 0.344 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.655 0.344 0.000
O24.0 Pre-existing diabetes mellitus, insulin-dependent
0.655 0.345 0.000
M45-M49 Spondylopathies
0.655 0.345 0.000
S62.6 Fracture of other finger
0.655 0.345 0.000
I73 Other peripheral vascular diseases
0.654 0.346 0.000
S92 Fracture of foot, except ankle
0.654 0.346 0.000
S49.8 Other specified injuries of shoulder and upper arm
0.653 0.347 0.000
I20.0 Unstable angina
0.652 0.348 0.000
E66.8 Other obesity
0.652 0.348 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.652 0.348 0.000
N99-N99 Other disorders of the genitourinary system
0.652 0.348 0.000
M00-M03 Infectious arthropathies
0.652 0.348 0.000
Z49 Care involving dialysis
0.652 0.348 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.651 0.349 0.000
Z41.8 Other procedures for purposes other than remedying health state
0.651 0.349 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.651 0.349 0.000
N46 Male infertility
0.651 0.349 0.000
N44 Torsion of testis
0.651 0.349 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.651 0.349 0.000
O86 Other puerperal infections
0.651 0.349 0.000
S42.00 Fracture of clavicle (closed)
0.651 0.349 0.000
S61 Open wound of wrist and hand
0.651 0.349 0.000
I95.2 Hypotension due to drugs
0.650 0.350 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.650 0.350 0.000
C97 Malignant neoplasms of independent (primary) multiple sites
0.650 0.350 0.000
G44 Other headache syndromes
0.650 0.350 0.000
S66.8 Injury of other muscles and tendons at wrist and hand level
0.649 0.351 0.000
S52.6 Fracture of lower end of both ulna and radius
0.648 0.352 0.000
S79 Other and unspecified injuries of hip and thigh
0.648 0.352 0.000
O72 Postpartum haemorrhage
0.648 0.352 0.000
C15.8 Overlapping lesion of oesophagus
0.648 0.352 0.000
C15.2 Abdominal part of oesophagus
0.648 0.352 0.000
C15.1 Thoracic part of oesophagus
0.648 0.352 0.000
C15.0 Cervical part of oesophagus
0.648 0.352 0.000
E22 Hyperfunction of pituitary gland
0.648 0.352 0.000
O41 Other disorders of amniotic fluid and membranes
0.647 0.353 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.647 0.353 0.000
E11.1 With ketoacidosis
0.647 0.353 0.000
S67 Crushing injury of wrist and hand
0.646 0.354 0.000
O21 Excessive vomiting in pregnancy
0.645 0.355 0.000
H90 Conductive and sensorineural hearing loss
0.645 0.355 0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered
0.644 0.356 0.000
Z41.1 Other plastic surgery for unacceptable cosmetic appearance
0.644 0.356 0.000
I74.8 Embolism and thrombosis of other arteries
0.644 0.356 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.644 0.356 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.644 0.356 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.644 0.356 0.000
E27.1 Primary adrenocortical insufficiency
0.643 0.357 0.000
M19.91 Arthrosis, unspecified (Shoulder region)
0.643 0.357 0.000
E14.3 With ophthalmic complications
0.643 0.357 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.643 0.357 0.000
N42.0 Calculus of prostate
0.641 0.359 0.000
H35.2 Other proliferative retinopathy
0.641 0.359 0.000
O82.0 Delivery by elective Caesarean section
0.641 0.359 0.000
O63 Long labour
0.640 0.360 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.640 0.360 0.000
N42.8 Other specified disorders of prostate
0.640 0.360 0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified
0.640 0.360 0.000
T88.5 Other complications of anaesthesia
0.640 0.360 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.639 0.360 0.000
S26 Injury of heart
0.639 0.360 0.000
S25 Injury of blood vessels of thorax
0.639 0.360 0.000
S24 Injury of nerves and spinal cord at thorax level
0.639 0.360 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.639 0.360 0.000
S21 Open wound of thorax
0.639 0.360 0.000
O42.9 Premature rupture of membranes, unspecified
0.639 0.360 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.639 0.361 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.639 0.361 0.000
E34 Other endocrine disorders
0.639 0.361 0.000
E32 Diseases of thymus
0.639 0.361 0.000
E31 Polyglandular dysfunction
0.639 0.361 0.000
E30 Disorders of puberty, not elsewhere classified
0.639 0.361 0.000
E26 Hyperaldosteronism
0.639 0.361 0.000
E25 Adrenogenital disorders
0.639 0.361 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.638 0.362 0.000
C81 Hodgkin's disease
0.636 0.364 0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours
0.636 0.364 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.635 0.365 0.000
S99 Other and unspecified injuries of ankle and foot
0.635 0.365 0.000
S42.9 Fracture of shoulder girdle, part unspecified
0.634 0.366 0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified
0.634 0.366 0.000
T87.4 Infection of amputation stump
0.632 0.368 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.632 0.368 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.631 0.369 0.000
S81.0 Open wound of knee
0.631 0.369 0.000
O23.5 Infections of the genital tract in pregnancy
0.630 0.370 0.000
M19.94 Arthrosis, unspecified (Hand)
0.630 0.370 0.000
S64.0 Injury of ulnar nerve at wrist and hand level
0.629 0.371 0.000
S49.9 Unspecified injury of shoulder and upper arm
0.629 0.371 0.000
S64.9 Injury of unspecified nerve at wrist and hand level
0.629 0.371 0.000
S64.8 Injury of other nerves at wrist and hand level
0.629 0.371 0.000
S64.7 Injury of multiple nerves at wrist and hand level
0.629 0.371 0.000
A30-A49 Other bacterial diseases
0.628 0.372 0.000
C75 Malignant neoplasm of other endocrine glands and related structures
0.628 0.372 0.000
C74 Malignant neoplasm of adrenal gland
0.628 0.372 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.627 0.373 0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours
0.627 0.373 0.000
H55-H59 Other disorders of eye and adnexa
0.627 0.373 0.000
E28 Ovarian dysfunction
0.627 0.373 0.000
M19.8 Other specified arthrosis
0.626 0.374 0.000
M19.2 Other secondary arthrosis
0.626 0.374 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.624 0.376 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.624 0.376 0.000
S91 Open wound of ankle and foot
0.624 0.376 0.000
C18.6 Descending colon
0.623 0.376 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.622 0.377 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.622 0.378 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.621 0.379 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.621 0.379 0.000
E16.4 Abnormal secretion of gastrin
0.621 0.379 0.000
E16.3 Increased secretion of glucagon
0.621 0.379 0.000
E16.1 Other hypoglycaemia
0.621 0.379 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.621 0.379 0.000
A65-A69 Other spirochaetal diseases
0.621 0.379 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.621 0.379 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.621 0.379 0.000
Z57.5 Occupational exposure to toxic agents in other industries
0.621 0.379 0.000
E27.9 Disorder of adrenal gland, unspecified
0.621 0.379 0.000
C45 Mesothelioma
0.620 0.380 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.619 0.381 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.618 0.382 0.000
G44.2 Tension-type headache
0.618 0.382 0.000
E46 Unspecified protein-energy malnutrition
0.618 0.382 0.000
M92 Other juvenile osteochondrosis
0.617 0.383 0.000
T88.4 Failed or difficult intubation
0.617 0.383 0.000
I05 Rheumatic mitral valve diseases
0.617 0.383 0.000
E24 Cushing's syndrome
0.617 0.383 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.616 0.383 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.616 0.384 0.000
I77.5 Necrosis of artery
0.616 0.384 0.000
I77.4 Coeliac artery compression syndrome
0.616 0.384 0.000
I77.3 Arterial fibromuscular dysplasia
0.616 0.384 0.000
I77.2 Rupture of artery
0.616 0.384 0.000
I77.0 Arteriovenous fistula, acquired
0.616 0.384 0.000
O22.4 Haemorrhoids in pregnancy
0.616 0.384 0.000
E14.9 Without complications
0.615 0.385 0.000
I22.8 Subsequent myocardial infarction of other sites
0.615 0.385 0.000
Z56.6 Other physical and mental strain related to work
0.615 0.385 0.000
G40 Epilepsy
0.614 0.386 0.000
C63 Malignant neoplasm of other and unspecified male genital organs
0.614 0.386 0.000
C60 Malignant neoplasm of penis
0.614 0.386 0.000
I70.9 Generalised and unspecified atherosclerosis
0.614 0.386 0.000
I70.8 Atherosclerosis of other arteries
0.614 0.386 0.000
I70.1 Atherosclerosis of renal artery
0.614 0.386 0.000
I77.6 Arteritis, unspecified
0.614 0.386 0.000
S61.1 Open wound of finger(s) with damage to nail
0.612 0.388 0.000
M14 Arthropathies in other diseases classified elsewhere
0.612 0.388 0.000
O81 Single delivery by forceps and vacuum extractor
0.612 0.388 0.000
M94 Other disorders of cartilage
0.611 0.389 0.000
O92 Other disorders of breast and lactation associated with childbirth
0.610 0.389 0.000
O91 Infections of breast associated with childbirth
0.610 0.389 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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