TreeWAS – Variant ID: rs1160133

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H40.9 Glaucoma, unspecified	0.480	0.520	0.000
H40 Glaucoma	0.400	0.600	0.000
H40.2 Primary angle-closure glaucoma	0.384	0.616	0.000
H40.5 Glaucoma secondary to other eye disorders	0.332	0.668	0.000
H40.6 Glaucoma secondary to drugs	0.287	0.713	0.000
H40.3 Glaucoma secondary to eye trauma	0.287	0.713	0.000
H40.0 Glaucoma suspect	0.282	0.718	0.000
H40.4 Glaucoma secondary to eye inflammation	0.281	0.719	0.000
H40.8 Other glaucoma	0.225	0.775	0.000
H40.1 Primary open-angle glaucoma	0.221	0.779	0.000
H40-H42 Glaucoma	0.178	0.822	0.000
H42 Glaucoma in diseases classified elsewhere	0.128	0.872	0.000
E23.0 Hypopituitarism	0.112	0.888	0.000
E23 Hypofunction and other disorders of pituitary gland	0.110	0.890	0.000
E20-E35 Disorders of other endocrine glands	0.105	0.895	0.000
E27 Other disorders of adrenal gland	0.105	0.895	0.000
E22 Hyperfunction of pituitary gland	0.100	0.900	0.000
E27.1 Primary adrenocortical insufficiency	0.098	0.902	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.093	0.907	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.092	0.908	0.000
H42.8 Glaucoma in other diseases classified elsewhere	0.092	0.908	0.000
H42.0 Glaucoma in endocrine, nutritional and metabolic diseases	0.092	0.908	0.000
E23.7 Disorder of pituitary gland, unspecified	0.089	0.911	0.000
E27.2 Addisonian crisis	0.086	0.914	0.000
E23.6 Other disorders of pituitary gland	0.085	0.915	0.000
E23.2 Diabetes insipidus	0.081	0.919	0.000
E29 Testicular dysfunction	0.081	0.919	0.000
E22.1 Hyperprolactinaemia	0.081	0.919	0.000
E34 Other endocrine disorders	0.079	0.921	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.079	0.921	0.000
E23.1 Drug-induced hypopituitarism	0.079	0.921	0.000
E28 Ovarian dysfunction	0.076	0.924	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.076	0.924	0.000
E32 Diseases of thymus	0.076	0.924	0.000
E31 Polyglandular dysfunction	0.076	0.924	0.000
E30 Disorders of puberty, not elsewhere classified	0.076	0.924	0.000
E25 Adrenogenital disorders	0.076	0.924	0.000
E27.8 Other specified disorders of adrenal gland	0.076	0.924	0.000
E27.5 Adrenomedullary hyperfunction	0.075	0.925	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.075	0.925	0.000
E27.0 Other adrenocortical overactivity	0.075	0.925	0.000
E24 Cushing's syndrome	0.074	0.926	0.000
E22.0 Acromegaly and pituitary gigantism	0.074	0.926	0.000
E27.9 Disorder of adrenal gland, unspecified	0.073	0.927	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.071	0.928	0.000
E22.8 Other hyperfunction of pituitary gland	0.071	0.928	0.000
E20 Hypoparathyroidism	0.071	0.929	0.000
E34.9 Endocrine disorder, unspecified	0.065	0.934	0.000
E26 Hyperaldosteronism	0.065	0.935	0.000
E29.1 Testicular hypofunction	0.063	0.937	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.062	0.938	0.000
E29.9 Testicular dysfunction, unspecified	0.058	0.942	0.000
E29.8 Other testicular dysfunction	0.058	0.942	0.000
E29.0 Testicular hyperfunction	0.058	0.942	0.000
E28.2 Polycystic ovarian syndrome	0.057	0.943	0.000
E34.5 Androgen resistance syndrome	0.057	0.943	0.000
E34.4 Constitutional tall stature	0.057	0.943	0.000
E34.3 Short stature, not elsewhere classified	0.057	0.943	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.057	0.943	0.000
E34.1 Other hypersecretion of intestinal hormones	0.057	0.943	0.000
E34.8 Other specified endocrine disorders	0.056	0.944	0.000
E28.9 Ovarian dysfunction, unspecified	0.055	0.945	0.000
E28.8 Other ovarian dysfunction	0.055	0.945	0.000
E28.1 Androgen excess	0.055	0.945	0.000
E28.0 Oestrogen excess	0.055	0.945	0.000
E25.9 Adrenogenital disorder, unspecified	0.054	0.945	0.000
E25.8 Other adrenogenital disorders	0.054	0.945	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.054	0.945	0.000
E30.9 Disorder of puberty, unspecified	0.054	0.945	0.000
E30.8 Other disorders of puberty	0.054	0.945	0.000
E30.1 Precocious puberty	0.054	0.945	0.000
E30.0 Delayed puberty	0.054	0.945	0.000
E31.9 Polyglandular dysfunction, unspecified	0.054	0.945	0.000
E31.8 Other polyglandular dysfunction	0.054	0.945	0.000
E31.1 Polyglandular hyperfunction	0.054	0.945	0.000
E31.0 Autoimmune polyglandular failure	0.054	0.945	0.000
E32.9 Disease of thymus, unspecified	0.054	0.945	0.000
E32.8 Other diseases of thymus	0.054	0.945	0.000
E32.1 Abscess of thymus	0.054	0.945	0.000
E32.0 Persistent hyperplasia of thymus	0.054	0.945	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.054	0.945	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.054	0.945	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.054	0.945	0.000
E24.8 Other Cushing's syndrome	0.053	0.946	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.053	0.946	0.000
E24.3 Ectopic ACTH syndrome	0.053	0.946	0.000
E24.2 Drug-induced Cushing's syndrome	0.053	0.946	0.000
E24.1 Nelson's syndrome	0.053	0.946	0.000
E24.0 Pituitary-dependent Cushing's disease	0.053	0.946	0.000
E28.3 Primary ovarian failure	0.052	0.948	0.000
E24.9 Cushing's syndrome, unspecified	0.052	0.948	0.000
E20.8 Other hypoparathyroidism	0.051	0.949	0.000
E20.1 Pseudohypoparathyroidism	0.051	0.949	0.000
E20.0 Idiopathic hypoparathyroidism	0.051	0.949	0.000
E34.0 Carcinoid syndrome	0.049	0.951	0.000
E20.9 Hypoparathyroidism, unspecified	0.047	0.953	0.000
E26.9 Hyperaldosteronism, unspecified	0.047	0.953	0.000
E26.8 Other hyperaldosteronism	0.047	0.953	0.000
E26.1 Secondary hyperaldosteronism	0.047	0.953	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.045	0.955	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.045	0.955	0.000
E21.4 Other specified disorders of parathyroid gland	0.045	0.955	0.000
E21.2 Other hyperparathyroidism	0.045	0.955	0.000
E21.0 Primary hyperparathyroidism	0.043	0.956	0.000
H93.1 Tinnitus	0.042	0.958	0.000
E26.0 Primary hyperaldosteronism	0.036	0.964	0.000
H93 Other disorders of ear, not elsewhere classified	0.034	0.966	0.000
E21.3 Hyperparathyroidism, unspecified	0.033	0.967	0.000
H93.8 Other specified disorders of ear	0.030	0.970	0.000
C44.5 Skin of trunk	0.000	0.970	0.030
C44 Other malignant neoplasms of skin	0.000	0.972	0.028
C44.2 Skin of ear and external auricular canal	0.000	0.973	0.027
C44.1 Skin of eyelid, including canthus	0.000	0.974	0.026
C44.4 Skin of scalp and neck	0.000	0.975	0.025
H93.9 Disorder of ear, unspecified	0.025	0.975	0.000
H93.3 Disorders of acoustic nerve	0.025	0.975	0.000
H93.2 Other abnormal auditory perceptions	0.025	0.975	0.000
H93.0 Degenerative and vascular disorders of ear	0.025	0.975	0.000
C44.3 Skin of other and unspecified parts of face	0.000	0.979	0.021
H90-H95 Other disorders of ear	0.021	0.979	0.000
C44.7 Skin of lower limb, including hip	0.000	0.979	0.021
C44.9 Malignant neoplasm of skin, unspecified	0.000	0.979	0.021
C44.8 Overlapping lesion of skin	0.000	0.979	0.020
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.019	0.981	0.000
H16 Keratitis	0.019	0.981	0.000
H17 Corneal scars and opacities	0.018	0.982	0.000
H17.9 Corneal scar and opacity, unspecified	0.018	0.982	0.000
Chapter VII Diseases of the eye and adnexa	0.018	0.982	0.000
H92 Otalgia and effusion of ear	0.017	0.983	0.000
H16.0 Corneal ulcer	0.016	0.984	0.000
H16.1 Other superficial keratitis without conjunctivitis	0.016	0.984	0.000
H16.4 Corneal neovascularisation	0.016	0.984	0.000
C44.6 Skin of upper limb, including shoulder	0.000	0.984	0.016
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.015	0.985	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.015	0.985	0.000
H90 Conductive and sensorineural hearing loss	0.015	0.985	0.000
H16.9 Keratitis, unspecified	0.015	0.985	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.015	0.985	0.000
H53-H54 Visual disturbances and blindness	0.015	0.985	0.000
C44.0 Skin of lip	0.000	0.985	0.015
H53.4 Visual field defects	0.015	0.985	0.000
H18 Other disorders of cornea	0.014	0.986	0.000
H53 Visual disturbances	0.014	0.986	0.000
H53.8 Other visual disturbances	0.014	0.986	0.000
H15 Disorders of sclera	0.014	0.986	0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.014	0.986	0.000
H16.8 Other keratitis	0.014	0.986	0.000
H16.3 Interstitial and deep keratitis	0.014	0.986	0.000
H16.2 Keratoconjunctivitis	0.014	0.986	0.000
H92.0 Otalgia	0.014	0.986	0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.013	0.986	0.000
H49 Paralytic strabismus	0.013	0.986	0.000
H17.8 Other corneal scars and opacities	0.013	0.987	0.000
H17.1 Other central corneal opacity	0.013	0.987	0.000
H17.0 Adherent leukoma	0.013	0.987	0.000
H92.1 Otorrhoea	0.013	0.987	0.000
H91 Other hearing loss	0.013	0.987	0.000
D50.8 Other iron deficiency anaemias	0.000	0.987	0.013
H21 Other disorders of iris and ciliary body	0.012	0.987	0.000
H92.2 Otorrhagia	0.012	0.987	0.000
H90.0 Conductive hearing loss, bilateral	0.012	0.987	0.000
H50.1 Divergent concomitant strabismus	0.012	0.988	0.000
Chapter VIII Diseases of the ear and mastoid process	0.012	0.988	0.000
H43-H45 Disorders of vitreous body and globe	0.012	0.988	0.000
H90.2 Conductive hearing loss, unspecified	0.012	0.988	0.000
H50 Other strabismus	0.012	0.988	0.000
H18.6 Keratoconus	0.012	0.988	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.012	0.988	0.000
H71 Cholesteatoma of middle ear	0.012	0.988	0.000
H18.0 Corneal pigmentations and deposits	0.011	0.989	0.000
H49.8 Other paralytic strabismus	0.011	0.989	0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.011	0.989	0.000
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.011	0.989	0.000
H51 Other disorders of binocular movement	0.011	0.989	0.000
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.011	0.989	0.000
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.011	0.989	0.000
H18.2 Other corneal oedema	0.011	0.989	0.000
H65-H75 Diseases of middle ear and mastoid	0.011	0.989	0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.011	0.989	0.000
H91.3 Deaf mutism, not elsewhere classified	0.011	0.989	0.000
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.011	0.989	0.000
H95.8 Other postprocedural disorders of ear and mastoid process	0.011	0.989	0.000
H18.8 Other specified disorders of cornea	0.011	0.989	0.000
H18.1 Bullous keratopathy	0.011	0.989	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.011	0.989	0.000
H49.9 Paralytic strabismus, unspecified	0.011	0.989	0.000
H52 Disorders of refraction and accommodation	0.011	0.989	0.000
H91.1 Presbycusis	0.011	0.989	0.000
H20 Iridocyclitis	0.011	0.989	0.000
H44 Disorders of globe	0.011	0.989	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.011	0.989	0.000
H18.7 Other corneal deformities	0.010	0.989	0.000
H18.3 Changes in corneal membranes	0.010	0.989	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.010	0.989	0.000
H49.0 Third [oculomotor] nerve palsy	0.010	0.990	0.000
H53.6 Night blindness	0.010	0.990	0.000
H53.5 Colour vision deficiencies	0.010	0.990	0.000
H53.3 Other disorders of binocular vision	0.010	0.990	0.000
H15.8 Other disorders of sclera	0.010	0.990	0.000
H49.2 Sixth [abducent] nerve palsy	0.010	0.990	0.000
H15.9 Disorder of sclera, unspecified	0.010	0.990	0.000
H15.1 Episcleritis	0.010	0.990	0.000
H15.0 Scleritis	0.010	0.990	0.000
H22.8 Other disorders of iris and ciliary body in diseases classified elsewhere	0.010	0.990	0.000
H22.1 Iridocyclitis in other diseases classified elsewhere	0.010	0.990	0.000
H22.0 Iridocyclitis in infectious and parasitic diseases classified elsewhere	0.010	0.990	0.000
H44.2 Degenerative myopia	0.010	0.990	0.000
H90.3 Sensorineural hearing loss, bilateral	0.010	0.990	0.000
H95.1 Other disorders following mastoidectomy	0.010	0.990	0.000
H18.9 Disorder of cornea, unspecified	0.010	0.990	0.000
H21.2 Degeneration of iris and ciliary body	0.010	0.990	0.000
H91.2 Sudden idiopathic hearing loss	0.010	0.990	0.000
H19.8 Other disorders of sclera and cornea in diseases classified elsewhere	0.010	0.990	0.000
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere	0.010	0.990	0.000
H19.2 Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere	0.010	0.990	0.000
H19.0 Scleritis and episcleritis in diseases classified elsewhere	0.010	0.990	0.000
H49.4 Progressive external ophthalmoplegia	0.010	0.990	0.000
H49.3 Total (external) ophthalmoplegia	0.010	0.990	0.000
H10-H13 Disorders of conjunctiva	0.010	0.990	0.000
H80.9 Otosclerosis, unspecified	0.010	0.990	0.000
H21.5 Other adhesions and disruptions of iris and ciliary body	0.010	0.990	0.000
H91.0 Ototoxic hearing loss	0.010	0.990	0.000
Z60.2 Living alone	0.010	0.990	0.000
H19.1 Herpesviral keratitis and keratoconjunctivitis	0.009	0.990	0.000
H18.4 Corneal degeneration	0.010	0.990	0.000
H21.0 Hyphaema	0.009	0.990	0.000
H53.1 Subjective visual disturbances	0.010	0.990	0.000
E10 Insulin-dependent diabetes mellitus	0.000	0.990	0.010
H90.5 Sensorineural hearing loss, unspecified	0.009	0.991	0.000
H80 Otosclerosis	0.009	0.991	0.000
H80-H83 Diseases of inner ear	0.009	0.991	0.000
H53.9 Visual disturbance, unspecified	0.009	0.991	0.000
H69 Other disorders of Eustachian tube	0.009	0.991	0.000
H74 Other disorders of middle ear and mastoid	0.009	0.991	0.000
H21.9 Disorder of iris and ciliary body, unspecified	0.009	0.991	0.000
H21.4 Pupillary membranes	0.009	0.991	0.000
H21.3 Cyst of iris, ciliary body and anterior chamber	0.009	0.991	0.000
E10.2 With renal complications	0.000	0.991	0.009
H49.1 Fourth [trochlear] nerve palsy	0.009	0.991	0.000
H52.7 Disorder of refraction, unspecified	0.009	0.991	0.000
H72 Perforation of tympanic membrane	0.009	0.991	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.009	0.991	0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere	0.009	0.991	0.000
H50.8 Other specified strabismus	0.009	0.991	0.000
H50.6 Mechanical strabismus	0.009	0.991	0.000
H50.4 Other and unspecified heterotropia	0.009	0.991	0.000
H50.3 Intermittent heterotropia	0.009	0.991	0.000
H50.2 Vertical strabismus	0.009	0.991	0.000
E10.9 Without complications	0.000	0.991	0.009
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere	0.008	0.991	0.000
H52.0 Hypermetropia	0.009	0.991	0.000
H52.3 Anisometropia and aniseikonia	0.008	0.991	0.000
E10.4 With neurological complications	0.000	0.992	0.008
H91.8 Other specified hearing loss	0.008	0.992	0.000
H51.9 Disorder of binocular movement, unspecified	0.008	0.992	0.000
H51.8 Other specified disorders of binocular movement	0.008	0.992	0.000
H51.2 Internuclear ophthalmoplegia	0.008	0.992	0.000
H51.1 Convergence insufficiency and excess	0.008	0.992	0.000
H51.0 Palsy of conjugate gaze	0.008	0.992	0.000
H44.1 Other endophthalmitis	0.008	0.992	0.000
H20.1 Chronic iridocyclitis	0.008	0.992	0.000
H21.1 Other vascular disorders of iris and ciliary body	0.008	0.992	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.008	0.992	0.000
H68 Eustachian salpingitis and obstruction	0.008	0.992	0.000
H67 Otitis media in diseases classified elsewhere	0.008	0.992	0.000
E10.3 With ophthalmic complications	0.000	0.992	0.008
E10.5 With peripheral circulatory complications	0.000	0.992	0.008
H52.6 Other disorders of refraction	0.008	0.992	0.000
H52.5 Disorders of accommodation	0.008	0.992	0.000
H52.4 Presbyopia	0.008	0.992	0.000
H69.8 Other specified disorders of Eustachian tube	0.008	0.992	0.000
I44.1 Atrioventricular block, second degree	0.000	0.992	0.008
H47 Other disorders of optic [2nd] nerve and visual pathways	0.008	0.992	0.000
E10.1 With ketoacidosis	0.000	0.992	0.008
H20.2 Lens-induced iridocyclitis	0.008	0.992	0.000
H44.9 Disorder of globe, unspecified	0.008	0.992	0.000
H44.8 Other disorders of globe	0.008	0.992	0.000
H44.7 Retained (old) intraocular foreign body, nonmagnetic	0.008	0.992	0.000
H44.6 Retained (old) intraocular foreign body, magnetic	0.008	0.992	0.000
H44.5 Degenerated conditions of globe	0.008	0.992	0.000
H44.4 Hypotony of eye	0.008	0.992	0.000
H44.3 Other degenerative disorders of globe	0.008	0.992	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.008	0.992	0.000
H46 Optic neuritis	0.008	0.992	0.000
H70 Mastoiditis and related conditions	0.008	0.992	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.008	0.992	0.000
H73 Other disorders of tympanic membrane	0.008	0.992	0.000
H18.5 Hereditary corneal dystrophies	0.007	0.992	0.000
E10.8 With unspecified complications	0.000	0.993	0.007
H25-H28 Disorders of lens	0.007	0.993	0.000
H13 Disorders of conjunctiva in diseases classified elsewhere	0.007	0.993	0.000
H50.0 Convergent concomitant strabismus	0.007	0.993	0.000
E10.6 With other specified complications	0.000	0.993	0.007
H27.0 Aphakia	0.007	0.993	0.000
H20.8 Other iridocyclitis	0.007	0.993	0.000
H52.2 Astigmatism	0.007	0.993	0.000
E10.7 With multiple complications	0.000	0.993	0.007
H69.9 Eustachian tube disorder, unspecified	0.007	0.993	0.000
H80.8 Other otosclerosis	0.007	0.993	0.000
H80.2 Cochlear otosclerosis	0.007	0.993	0.000
H80.1 Otosclerosis involving oval window, obliterative	0.007	0.993	0.000
H80.0 Otosclerosis involving oval window, nonobliterative	0.007	0.993	0.000
H82 Vertiginous syndromes in diseases classified elsewhere	0.007	0.993	0.000
H69.0 Patulous Eustachian tube	0.007	0.993	0.000
H47.1 Papilloedema, unspecified	0.007	0.993	0.000
H74.1 Adhesive middle ear disease	0.007	0.993	0.000
H20.9 Iridocyclitis, unspecified	0.007	0.993	0.000
H54 Blindness and low vision	0.007	0.993	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.007	0.993	0.000
H60-H62 Diseases of external ear	0.007	0.993	0.000
H74.4 Polyp of middle ear	0.007	0.993	0.000
H27 Other disorders of lens	0.007	0.993	0.000
H72.2 Other marginal perforations of tympanic membrane	0.007	0.993	0.000
H21.8 Other specified disorders of iris and ciliary body	0.006	0.993	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.007	0.993	0.000
H45.8 Other disorders of vitreous body and globe in diseases classified elsewhere	0.006	0.993	0.000
H45.1 Endophthalmitis in diseases classified elsewhere	0.006	0.993	0.000
H45.0 Vitreous haemorrhage in diseases classified elsewhere	0.006	0.993	0.000
H53.2 Diplopia	0.007	0.993	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.006	0.993	0.000
H20.0 Acute and subacute iridocyclitis	0.006	0.993	0.000
H72.8 Other perforations of tympanic membrane	0.006	0.993	0.000
H44.0 Purulent endophthalmitis	0.006	0.993	0.000
H72.1 Attic perforation of tympanic membrane	0.006	0.993	0.000
H48.8 Other disorders of optic nerve and visual pathways in diseases classified elsewhere	0.006	0.993	0.000
H48.1 Retrobulbar neuritis in diseases classified elsewhere	0.006	0.993	0.000
H48.0 Optic atrophy in diseases classified elsewhere	0.006	0.993	0.000
H50.9 Strabismus, unspecified	0.006	0.994	0.000
H74.0 Tympanosclerosis	0.006	0.994	0.000
H50.5 Heterophoria	0.006	0.994	0.000
H66 Suppurative and unspecified otitis media	0.006	0.994	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.006	0.994	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.006	0.994	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.006	0.994	0.000
H68.1 Obstruction of Eustachian tube	0.006	0.994	0.000
H68.0 Eustachian salpingitis	0.006	0.994	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.006	0.994	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.006	0.994	0.000
H10 Conjunctivitis	0.006	0.994	0.000
E10.0 With coma	0.000	0.994	0.006
H54.9 Unspecified visual impairment (binocular)	0.006	0.994	0.000
H47.7 Disorder of visual pathways, unspecified	0.006	0.994	0.000
H47.6 Disorders of visual cortex	0.006	0.994	0.000
H47.5 Disorders of other visual pathways	0.006	0.994	0.000
H47.4 Disorders of optic chiasm	0.006	0.994	0.000
H70.8 Other mastoiditis and related conditions	0.006	0.994	0.000
H70.2 Petrositis	0.006	0.994	0.000
H70.1 Chronic mastoiditis	0.006	0.994	0.000
H70.0 Acute mastoiditis	0.006	0.994	0.000
H54.5 Low vision, one eye	0.006	0.994	0.000
H73.1 Chronic myringitis	0.006	0.994	0.000
H73.0 Acute myringitis	0.006	0.994	0.000
H11 Other disorders of conjunctiva	0.006	0.994	0.000
H47.3 Other disorders of optic disk	0.005	0.994	0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere	0.005	0.994	0.000
H13.8 Other disorders of conjunctiva in diseases classified elsewhere	0.005	0.994	0.000
H13.3 Ocular pemphigoid	0.005	0.994	0.000
H13.2 Conjunctivitis in other diseases classified elsewhere	0.005	0.994	0.000
H13.1 Conjunctivitis in infectious and parasitic diseases classified elsewhere	0.005	0.994	0.000
H13.0 Filarial infection of conjunctiva	0.005	0.994	0.000
H70.9 Mastoiditis, unspecified	0.005	0.994	0.000
H47.0 Disorders of optic nerve, not elsewhere classified	0.005	0.995	0.000
H53.0 Amblyopia ex anopsia	0.005	0.995	0.000
H54.6 Unqualified visual loss, one eye	0.005	0.995	0.000
H54.3 Unqualified visual loss, both eyes	0.005	0.995	0.000
H54.2 Low vision, both eyes	0.005	0.995	0.000
H54.1 Blindness, one eye, low vision, other eye	0.005	0.995	0.000
S52.60 Fracture of lower end of both ulna and radius (closed)	0.005	0.995	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.005	0.995	0.000
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue	0.000	0.995	0.005
H27.9 Disorder of lens, unspecified	0.005	0.995	0.000
H66.0 Acute suppurative otitis media	0.005	0.995	0.000
H60 Otitis externa	0.005	0.995	0.000
H81 Disorders of vestibular function	0.005	0.995	0.000
H66.4 Suppurative otitis media, unspecified	0.005	0.995	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.000	0.995	0.005
H55-H59 Other disorders of eye and adnexa	0.005	0.995	0.000
H11.2 Conjunctival scars	0.005	0.995	0.000
Z60 Problems related to social environment	0.005	0.995	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.005	0.995	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.005	0.995	0.000
H10.8 Other conjunctivitis	0.004	0.995	0.000
H10.5 Blepharoconjunctivitis	0.004	0.995	0.000
H10.3 Acute conjunctivitis, unspecified	0.004	0.995	0.000
H10.2 Other acute conjunctivitis	0.004	0.995	0.000
H10.1 Acute atopic conjunctivitis	0.004	0.995	0.000
H10.0 Mucopurulent conjunctivitis	0.004	0.995	0.000
I44 Atrioventricular and left bundle-branch block	0.000	0.995	0.005
M43.16 Spondylolisthesis (Lumbar region)	0.000	0.995	0.005
H83 Other diseases of inner ear	0.004	0.995	0.000
H60.8 Other otitis externa	0.005	0.995	0.000
H52.1 Myopia	0.005	0.995	0.000
H10.4 Chronic conjunctivitis	0.004	0.995	0.000
H11.4 Other conjunctival vascular disorders and cysts	0.004	0.995	0.000
H47.2 Optic atrophy	0.004	0.996	0.000
H27.1 Dislocation of lens	0.004	0.996	0.000
H81.9 Disorder of vestibular function, unspecified	0.004	0.996	0.000
I44.3 Other and unspecified atrioventricular block	0.000	0.996	0.004
H28.8 Other disorders of lens in diseases classified elsewhere	0.004	0.996	0.000
H28.2 Cataract in other diseases classified elsewhere	0.004	0.996	0.000
H28.1 Cataract in other endocrine, nutritional and metabolic diseases	0.004	0.996	0.000
H28.0 Diabetic cataract	0.004	0.996	0.000
H11.8 Other specified disorders of conjunctiva	0.004	0.996	0.000
H66.3 Other chronic suppurative otitis media	0.004	0.996	0.000
H11.0 Pterygium	0.004	0.996	0.000
H81.8 Other disorders of vestibular function	0.004	0.996	0.000
H54.7 Unspecified visual loss	0.004	0.996	0.000
I44.0 Atrioventricular block, first degree	0.000	0.996	0.004
C45.0 Mesothelioma of pleura	0.000	0.996	0.004
H27.8 Other specified disorders of lens	0.004	0.996	0.000
H11.1 Conjunctival degenerations and deposits	0.004	0.996	0.000
H62.8 Other disorders of external ear in diseases classified elsewhere	0.004	0.996	0.000
H62.4 Otitis externa in other diseases classified elsewhere	0.004	0.996	0.000
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.004	0.996	0.000
H62.2 Otitis externa in mycoses	0.004	0.996	0.000
H62.1 Otitis externa in viral diseases classified elsewhere	0.004	0.996	0.000
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.004	0.996	0.000
H60.9 Otitis externa, unspecified	0.004	0.996	0.000
R23.8 Other and unspecified skin changes	0.000	0.996	0.004
I44.7 Left bundle-branch block, unspecified	0.000	0.996	0.004
H60.4 Cholesteatoma of external ear	0.004	0.996	0.000
H60.2 Malignant otitis externa	0.004	0.996	0.000
H60.0 Abscess of external ear	0.004	0.996	0.000
H81.4 Vertigo of central origin	0.004	0.996	0.000
H81.3 Other peripheral vertigo	0.004	0.996	0.000
S52.6 Fracture of lower end of both ulna and radius	0.004	0.996	0.000
H60.3 Other infective otitis externa	0.004	0.996	0.000
H11.9 Disorder of conjunctiva, unspecified	0.004	0.996	0.000
C45 Mesothelioma	0.000	0.996	0.004
Z60.9 Problem related to social environment, unspecified	0.004	0.996	0.000
Z60.8 Other problems related to social environment	0.004	0.996	0.000
Z60.5 Target of perceived adverse discrimination and persecution	0.004	0.996	0.000
Z60.4 Social exclusion and rejection	0.004	0.996	0.000
Z60.3 Acculturation difficulty	0.004	0.996	0.000
Z60.1 Atypical parenting situation	0.004	0.996	0.000
Z60.0 Problems of adjustment to life-cycle transitions	0.004	0.996	0.000
H10.9 Conjunctivitis, unspecified	0.003	0.996	0.000
H81.2 Vestibular neuronitis	0.004	0.996	0.000
H72.0 Central perforation of tympanic membrane	0.003	0.996	0.000
I44.5 Left posterior fascicular block	0.000	0.996	0.004
C45.9 Mesothelioma, unspecified	0.000	0.996	0.004
H60.5 Acute otitis externa, non-infective	0.003	0.996	0.000
H83.9 Disease of inner ear, unspecified	0.003	0.996	0.000
H83.8 Other specified diseases of inner ear	0.003	0.996	0.000
H83.3 Noise effects on inner ear	0.003	0.996	0.000
H83.2 Labyrinthine dysfunction	0.003	0.996	0.000
H83.1 Labyrinthine fistula	0.003	0.996	0.000
H81.1 Benign paroxysmal vertigo	0.003	0.996	0.000
D61.9 Aplastic anaemia, unspecified	0.000	0.997	0.003
I44.4 Left anterior fascicular block	0.000	0.997	0.003
K26.4 Chronic or unspecified with haemorrhage	0.003	0.997	0.000
C45.7 Mesothelioma of other sites	0.000	0.997	0.003
H11.3 Conjunctival haemorrhage	0.003	0.997	0.000
O00.1 Tubal pregnancy	0.000	0.997	0.003
S52.00 Fracture of upper end of ulna (closed)	0.003	0.997	0.000
H60.1 Cellulitis of external ear	0.003	0.997	0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.002	0.997	0.001
B16.9 Acute hepatitis B without delta-agent and without hepatic coma	0.003	0.997	0.000
S52.0 Fracture of upper end of ulna	0.003	0.997	0.000
H43 Disorders of vitreous body	0.003	0.997	0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.003	0.997	0.000
H65 Nonsuppurative otitis media	0.003	0.997	0.000
I44.6 Other and unspecified fascicular block	0.000	0.997	0.003
H61 Other disorders of external ear	0.003	0.997	0.000
S12.20 Fracture of other specified cervical vertebra (closed)	0.000	0.997	0.003
S52 Fracture of forearm	0.003	0.997	0.000
H54.0 Blindness, both eyes	0.003	0.997	0.000
D50 Iron deficiency anaemia	0.000	0.997	0.003
I44.2 Atrioventricular block, complete	0.000	0.997	0.003
H30-H36 Disorders of choroid and retina	0.003	0.997	0.000
H91.9 Hearing loss, unspecified	0.003	0.997	0.000
H54.4 Blindness, one eye	0.003	0.997	0.000
C45.2 Mesothelioma of pericardium	0.000	0.997	0.003
C45.1 Mesothelioma of peritoneum	0.000	0.997	0.003
H57 Other disorders of eye and adnexa	0.003	0.997	0.000
M43.1 Spondylolisthesis	0.000	0.997	0.003
B17.8 Other specified acute viral hepatitis	0.003	0.997	0.000
H73.8 Other specified disorders of tympanic membrane	0.003	0.997	0.000
S52.2 Fracture of shaft of ulna	0.003	0.997	0.000
H61.8 Other specified disorders of external ear	0.003	0.997	0.000
R23.1 Pallor	0.000	0.997	0.003
S52.61 Fracture of lower end of both ulna and radius (open)	0.003	0.997	0.000
S52.20 Fracture of shaft of ulna (closed)	0.003	0.997	0.000
S52.01 Fracture of upper end of ulna (open)	0.003	0.997	0.000
S52.8 Fracture of other parts of forearm	0.003	0.997	0.000
B17 Other acute viral hepatitis	0.003	0.997	0.000
M43.17 Spondylolisthesis (Lumbosacral region)	0.000	0.997	0.003
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.000	0.997	0.003
B16 Acute hepatitis B	0.003	0.997	0.000
C48.2 Peritoneum, unspecified	0.000	0.997	0.003
H61.1 Non-infective disorders of pinna	0.003	0.997	0.000
H31 Other disorders of choroid	0.003	0.997	0.000
R23 Other skin changes	0.000	0.997	0.003
C48.1 Specified parts of peritoneum	0.000	0.997	0.003
S52.7 Multiple fractures of forearm	0.003	0.997	0.000
H58.9 Other specified disorders of eye and adnexa in diseases classified elsewhere	0.002	0.997	0.001
H58.1 Visual disturbances in diseases classified elsewhere	0.002	0.997	0.001
H58.0 Anomalies of pupillary function in diseases classified elsewhere	0.002	0.997	0.001
H30 Chorioretinal inflammation	0.003	0.997	0.000
S52.80 Fracture of other parts of forearm (closed)	0.002	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations