TreeWAS – Variant ID: rs11640986

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	1.000	0.000	0.000
T81 Complications of procedures, not elsewhere classified	0.999	0.001	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.997	0.003	0.000
T81.4 Infection following a procedure, not elsewhere classified	0.997	0.003	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.995	0.005	0.000
S80-S89 Injuries to the knee and lower leg	0.991	0.009	0.000
T81.3 Disruption of operation wound, not elsewhere classified	0.984	0.016	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.982	0.018	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.978	0.022	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.976	0.024	0.000
T40.2 Other opioids	0.958	0.042	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.956	0.044	0.000
S81 Open wound of lower leg	0.938	0.062	0.000
S10-S19 Injuries to the neck	0.908	0.092	0.000
T39.0 Salicylates	0.899	0.101	0.000
S86 Injury of muscle and tendon at lower leg level	0.897	0.103	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.891	0.109	0.000
T90 Sequelae of injuries of head	0.882	0.118	0.000
T81.7 Vascular complications following a procedure, not elsewhere classified	0.874	0.126	0.000
T80 Complications following infusion, transfusion and therapeutic injection	0.871	0.129	0.000
S00-S09 Injuries to the head	0.868	0.132	0.000
S80 Superficial injury of lower leg	0.858	0.142	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.858	0.142	0.000
S81.8 Open wound of other parts of lower leg	0.857	0.143	0.000
S01 Open wound of head	0.856	0.144	0.000
T39.1 4-Aminophenol derivatives	0.854	0.146	0.000
T42.4 Benzodiazepines	0.847	0.153	0.000
S20-S29 Injuries to the thorax	0.845	0.155	0.000
S12 Fracture of neck	0.844	0.156	0.000
T14 Injury of unspecified body region	0.834	0.166	0.000
T40.4 Other synthetic narcotics	0.832	0.168	0.000
S81.0 Open wound of knee	0.829	0.171	0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.825	0.175	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.824	0.176	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.823	0.177	0.000
T90.2 Sequelae of fracture of skull and facial bones	0.822	0.178	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.819	0.181	0.000
T92 Sequelae of injuries of upper limb	0.819	0.181	0.000
S86.8 Injury of other muscles and tendons at lower leg level	0.818	0.182	0.000
T00-T07 Injuries involving multiple body regions	0.816	0.184	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.807	0.193	0.000
S80.0 Contusion of knee	0.803	0.197	0.000
S01.1 Open wound of eyelid and periocular area	0.797	0.203	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.792	0.208	0.000
T42.1 Iminostilbenes	0.791	0.209	0.000
T42.0 Hydantoin derivatives	0.783	0.217	0.000
T51 Toxic effect of alcohol	0.778	0.222	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.777	0.223	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.775	0.225	0.000
T81.9 Unspecified complication of procedure	0.774	0.226	0.000
T95 Sequelae of burns, corrosions and frostbite	0.773	0.227	0.000
T81.8 Other complications of procedures, not elsewhere classified	0.762	0.238	0.000
T86 Failure and rejection of transplanted organs and tissues	0.761	0.239	0.000
T14.0 Superficial injury of unspecified body region	0.760	0.240	0.000
T92.1 Sequelae of fracture of arm	0.759	0.241	0.000
S01.5 Open wound of lip and oral cavity	0.757	0.243	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.750	0.250	0.000
S12.2 Fracture of other specified cervical vertebra	0.750	0.250	0.000
S50-S59 Injuries to the elbow and forearm	0.748	0.252	0.000
S01.0 Open wound of scalp	0.747	0.253	0.000
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.746	0.254	0.000
S82 Fracture of lower leg, including ankle	0.743	0.257	0.000
T91 Sequelae of injuries of neck and trunk	0.741	0.259	0.000
S89 Other and unspecified injuries of lower leg	0.741	0.259	0.000
T98 Sequelae of other and unspecified effects of external causes	0.737	0.263	0.000
S01.2 Open wound of nose	0.735	0.265	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.731	0.269	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.729	0.271	0.000
T36 Poisoning by systemic antibiotics	0.728	0.272	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.727	0.273	0.000
T51.0 Ethanol	0.727	0.273	0.000
T87 Complications peculiar to reattachment and amputation	0.723	0.277	0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified	0.721	0.279	0.000
T33-T35 Frostbite	0.717	0.283	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.717	0.283	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.717	0.283	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.717	0.283	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.717	0.283	0.000
T90.5 Sequelae of intracranial injury	0.716	0.283	0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure	0.716	0.284	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.713	0.287	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.713	0.287	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.713	0.287	0.000
T42.3 Barbiturates	0.713	0.287	0.000
T42.2 Succinimides and oxazolidinediones	0.713	0.287	0.000
T88.7 Unspecified adverse effect of drug or medicament	0.712	0.288	0.000
T80.2 Infections following infusion, transfusion and therapeutic injection	0.712	0.288	0.000
S88 Traumatic amputation of lower leg	0.711	0.289	0.000
S87 Crushing injury of lower leg	0.711	0.289	0.000
S85 Injury of blood vessels at lower leg level	0.711	0.289	0.000
S84 Injury of nerves at lower leg level	0.711	0.289	0.000
S20 Superficial injury of thorax	0.708	0.292	0.000
S01.8 Open wound of other parts of head	0.705	0.295	0.000
S14 Injury of nerves and spinal cord at neck level	0.704	0.296	0.000
T45.0 Antiallergic and antiemetic drugs	0.701	0.299	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.701	0.299	0.000
T40.8 Lysergide [LSD]	0.701	0.299	0.000
T40.7 Cannabis (derivatives)	0.701	0.299	0.000
T40.5 Cocaine	0.701	0.299	0.000
T40.3 Methadone	0.701	0.299	0.000
T40.1 Heroin	0.701	0.299	0.000
T40.0 Opium	0.701	0.299	0.000
T59 Toxic effect of other gases, fumes and vapours	0.701	0.299	0.000
T39.4 Antirheumatics, not elsewhere classified	0.700	0.300	0.000
T39.2 Pyrazolone derivatives	0.700	0.300	0.000
T66-T78 Other and unspecified effects of external causes	0.699	0.301	0.000
T92.0 Sequelae of open wound of upper limb	0.696	0.304	0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure	0.695	0.305	0.000
S80.7 Multiple superficial injuries of lower leg	0.688	0.312	0.000
S12.7 Multiple fractures of cervical spine	0.688	0.312	0.000
S01.4 Open wound of cheek and temporomandibular area	0.688	0.312	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.687	0.313	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.685	0.315	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.685	0.315	0.000
S12.20 Fracture of other specified cervical vertebra (closed)	0.682	0.318	0.000
S82.1 Fracture of upper end of tibia	0.681	0.319	0.000
S27 Injury of other and unspecified intrathoracic organs	0.677	0.323	0.000
S81.7 Multiple open wounds of lower leg	0.672	0.328	0.000
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.668	0.332	0.000
T01 Open wounds involving multiple body regions	0.667	0.333	0.000
T14.1 Open wound of unspecified body region	0.660	0.340	0.000
S29 Other and unspecified injuries of thorax	0.659	0.341	0.000
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.658	0.342	0.000
S17 Crushing injury of neck	0.651	0.349	0.000
S15 Injury of blood vessels at neck level	0.651	0.349	0.000
S11 Open wound of neck	0.651	0.349	0.000
S18 Traumatic amputation at neck level	0.651	0.349	0.000
S16 Injury of muscle and tendon at neck level	0.651	0.349	0.000
S12.9 Fracture of neck, part unspecified	0.647	0.352	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.646	0.354	0.000
T92.9 Sequelae of unspecified injury of upper limb	0.644	0.356	0.000
S86.0 Injury of Achilles tendon	0.643	0.357	0.000
S86.7 Injury of multiple muscles and tendons at lower leg level	0.643	0.357	0.000
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.643	0.357	0.000
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.643	0.357	0.000
T95.2 Sequelae of burn, corrosion and frostbite of upper limb	0.642	0.358	0.000
S82.3 Fracture of lower end of tibia	0.641	0.359	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.640	0.360	0.000
S83.2 Tear of meniscus, current	0.640	0.360	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.640	0.360	0.000
T14.6 Injury of tendons and muscles of unspecified body region	0.639	0.361	0.000
T09 Other injuries of spine and trunk, level unspecified	0.639	0.361	0.000
T12.X1 Fracture of lower limb, level unspecified (open)	0.639	0.361	0.000
T12.X0 Fracture of lower limb, level unspecified (closed)	0.639	0.361	0.000
T12 Fracture of lower limb, level unspecified	0.639	0.361	0.000
T10.X1 Fracture of upper limb, level unspecified (open)	0.639	0.361	0.000
T10.X0 Fracture of upper limb, level unspecified (closed)	0.639	0.361	0.000
T10 Fracture of upper limb, level unspecified	0.639	0.361	0.000
T08.X1 Fracture of spine, level unspecified (open)	0.639	0.361	0.000
T08.X0 Fracture of spine, level unspecified (closed)	0.639	0.361	0.000
T08 Fracture of spine, level unspecified	0.639	0.361	0.000
S82.10 Fracture of upper end of tibia (closed)	0.637	0.363	0.000
T91.1 Sequelae of fracture of spine	0.633	0.367	0.000
T90.3 Sequelae of injury of cranial nerves	0.632	0.367	0.000
T90.1 Sequelae of open wound of head	0.632	0.367	0.000
T90.0 Sequelae of superficial injury of head	0.632	0.367	0.000
T90.9 Sequelae of unspecified injury of head	0.632	0.368	0.000
T90.8 Sequelae of other specified injuries of head	0.630	0.369	0.000
S20.2 Contusion of thorax	0.630	0.370	0.000
S13.6 Sprain and strain of joints and ligaments of other and unspecified parts of neck	0.629	0.371	0.000
S12.1 Fracture of second cervical vertebra	0.629	0.371	0.000
S81.9 Open wound of lower leg, part unspecified	0.629	0.371	0.000
T80.9 Unspecified complication following infusion, transfusion and therapeutic injection	0.625	0.375	0.000
T80.6 Other serum reactions	0.625	0.375	0.000
T80.5 Anaphylactic shock due to serum	0.625	0.375	0.000
T80.4 Rh incompatibility reaction	0.625	0.375	0.000
T80.3 ABO incompatibility reaction	0.625	0.375	0.000
T80.0 Air embolism following infusion, transfusion and therapeutic injection	0.625	0.375	0.000
T86.8 Failure and rejection of other transplanted organs and tissues	0.625	0.375	0.000
S51 Open wound of forearm	0.624	0.376	0.000
T20 Burn and corrosion of head and neck	0.624	0.376	0.000
S08 Traumatic amputation of part of head	0.623	0.377	0.000
S07 Crushing injury of head	0.623	0.377	0.000
S04 Injury of cranial nerves	0.623	0.377	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.623	0.377	0.000
T14.9 Injury, unspecified	0.622	0.378	0.000
T23 Burn and corrosion of wrist and hand	0.622	0.378	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.619	0.380	0.000
T00 Superficial injuries involving multiple body regions	0.615	0.385	0.000
T65 Toxic effect of other and unspecified substances	0.615	0.385	0.000
T62 Toxic effect of other noxious substances eaten as food	0.615	0.385	0.000
T61 Toxic effect of noxious substances eaten as seafood	0.615	0.385	0.000
T60 Toxic effect of pesticides	0.615	0.385	0.000
T57 Toxic effect of other inorganic substances	0.615	0.385	0.000
T56 Toxic effect of metals	0.615	0.385	0.000
T54 Toxic effect of corrosive substances	0.615	0.385	0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.615	0.385	0.000
T52 Toxic effect of organic solvents	0.615	0.385	0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.615	0.385	0.000
T55 Toxic effect of soaps and detergents	0.615	0.385	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.612	0.388	0.000
T79-T79 Certain early complications of trauma	0.611	0.389	0.000
S01.7 Multiple open wounds of head	0.610	0.389	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.607	0.393	0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.606	0.394	0.000
S26 Injury of heart	0.606	0.394	0.000
S25 Injury of blood vessels of thorax	0.606	0.394	0.000
S24 Injury of nerves and spinal cord at thorax level	0.606	0.394	0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.606	0.394	0.000
S21 Open wound of thorax	0.606	0.394	0.000
S12.8 Fracture of other parts of neck	0.605	0.395	0.000
S12.0 Fracture of first cervical vertebra	0.605	0.395	0.000
S80.9 Superficial injury of lower leg, unspecified	0.605	0.395	0.000
T43.6 Psychostimulants with abuse potential	0.602	0.398	0.000
T21 Burn and corrosion of trunk	0.600	0.399	0.000
S05 Injury of eye and orbit	0.600	0.400	0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.599	0.401	0.000
T11 Other injuries of upper limb, level unspecified	0.599	0.401	0.000
T80.1 Vascular complications following infusion, transfusion and therapeutic injection	0.598	0.402	0.000
T14.2 Fracture of unspecified body region	0.598	0.402	0.000
T14.8 Other injuries of unspecified body region	0.598	0.402	0.000
T14.7 Crushing injury and traumatic amputation of unspecified body region	0.598	0.402	0.000
T14.5 Injury of blood vessel(s) of unspecified body region	0.598	0.402	0.000
T14.4 Injury of nerve(s) of unspecified body region	0.598	0.402	0.000
T14.3 Dislocation, sprain and strain of unspecified body region	0.598	0.402	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.590	0.410	0.000
T45.8 Other primarily systemic and haematological agents	0.590	0.410	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.590	0.410	0.000
T45.6 Fibrinolysis-affecting drugs	0.590	0.410	0.000
T45.5 Anticoagulants	0.590	0.410	0.000
T45.4 Iron and its compounds	0.590	0.410	0.000
T45.3 Enzymes, not elsewhere classified	0.590	0.410	0.000
T45.2 Vitamins, not elsewhere classified	0.590	0.410	0.000
S59 Other and unspecified injuries of forearm	0.589	0.411	0.000
T13 Other injuries of lower limb, level unspecified	0.589	0.411	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.589	0.411	0.000
T59.8 Other specified gases, fumes and vapours	0.588	0.412	0.000
T25 Burn and corrosion of ankle and foot	0.587	0.413	0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.587	0.413	0.000
T92.4 Sequelae of injury of nerve of upper limb	0.587	0.413	0.000
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified	0.586	0.414	0.000
T06 Other injuries involving multiple body regions, not elsewhere classified	0.585	0.415	0.000
T05 Traumatic amputations involving multiple body regions	0.585	0.415	0.000
T04 Crushing injuries involving multiple body regions	0.585	0.415	0.000
T03 Dislocations, sprains and strains involving multiple body regions	0.585	0.415	0.000
T07 Unspecified multiple injuries	0.585	0.415	0.000
T02 Fractures involving multiple body regions	0.581	0.419	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.579	0.421	0.000
S12.70 Multiple fractures of cervical spine (closed)	0.576	0.424	0.000
S13.1 Dislocation of cervical vertebra	0.575	0.425	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.572	0.427	0.000
S50 Superficial injury of forearm	0.572	0.427	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.570	0.430	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.570	0.430	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.569	0.431	0.000
T88.9 Complication of surgical and medical care, unspecified	0.568	0.432	0.000
T88.3 Malignant hyperthermia due to anaesthesis	0.568	0.432	0.000
T88.2 Shock due to anaesthesia	0.568	0.432	0.000
T88.1 Other complications following immunisation, not elsewhere classified	0.568	0.432	0.000
T88.0 Infection following immunisation	0.568	0.432	0.000
S82.30 Fracture of lower end of tibia (closed)	0.568	0.432	0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.566	0.434	0.000
S80.1 Contusion of other and unspecified parts of lower leg	0.565	0.435	0.000
S89.9 Unspecified injury of lower leg	0.564	0.436	0.000
T86.0 Bone-marrow transplant rejection	0.564	0.436	0.000
S02 Fracture of skull and facial bones	0.564	0.436	0.000
S20.3 Other superficial injuries of front wall of thorax	0.561	0.439	0.000
S70-S79 Injuries to the hip and thigh	0.560	0.440	0.000
T01.8 Open wounds involving other combinations of body regions	0.560	0.440	0.000
T90.4 Sequelae of injury of eye and orbit	0.558	0.442	0.000
T51.8 Other alcohols	0.558	0.442	0.000
T51.3 Fusel oil	0.558	0.442	0.000
T51.2 2-Propanol	0.558	0.442	0.000
T51.1 Methanol	0.558	0.442	0.000
T40.6 Other and unspecified narcotics	0.557	0.443	0.000
S14.1 Other and unspecified injuries of cervical spinal cord	0.557	0.443	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.557	0.443	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.557	0.443	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.557	0.443	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.557	0.443	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.557	0.443	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.557	0.443	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.557	0.443	0.000
T44.0 Anticholinesterase agents	0.557	0.443	0.000
T43.9 Psychotropic drug, unspecified	0.556	0.444	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.556	0.444	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.556	0.444	0.000
T95.9 Sequelae of unspecified burn, corrosion and frostbite	0.554	0.446	0.000
T95.8 Sequelae of other specified burn, corrosion and frostbite	0.554	0.446	0.000
T95.4 Sequelae of burn and corrosion classifiable only according to extent of body surface involved	0.554	0.446	0.000
T95.3 Sequelae of burn, corrosion and frostbite of lower limb	0.554	0.446	0.000
T95.1 Sequelae of burn, corrosion and frostbite of trunk	0.554	0.446	0.000
T95.0 Sequelae of burn, corrosion and frostbite of head and neck	0.554	0.446	0.000
T88.5 Other complications of anaesthesia	0.553	0.447	0.000
S90-S99 Injuries to the ankle and foot	0.549	0.451	0.000
T71 Asphyxiation	0.547	0.452	0.000
T91.2 Sequelae of other fracture of thorax and pelvis	0.547	0.453	0.000
T63 Toxic effect of contact with venomous animals	0.546	0.454	0.000
T78 Adverse effects, not elsewhere classified	0.546	0.454	0.000
T86.9 Failure and rejection of unspecified transplanted organ and tissue	0.545	0.454	0.000
T86.4 Liver transplant failure and rejection	0.545	0.454	0.000
T86.3 Heart-lung transplant failure and rejection	0.545	0.454	0.000
T86.2 Heart transplant failure and rejection	0.545	0.454	0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.541	0.459	0.000
T87.4 Infection of amputation stump	0.539	0.461	0.000
S82.7 Multiple fractures of lower leg	0.539	0.461	0.000
S13.5 Sprain and strain of thyroid region	0.538	0.462	0.000
S13.3 Multiple dislocations of neck	0.538	0.462	0.000
S13.2 Dislocation of other and unspecified parts of neck	0.538	0.462	0.000
S13.0 Traumatic rupture of cervical intervertebral disk	0.538	0.462	0.000
S12.21 Fracture of other specified cervical vertebra (open)	0.538	0.462	0.000
S40-S49 Injuries to the shoulder and upper arm	0.537	0.463	0.001
S58 Traumatic amputation of forearm	0.537	0.463	0.000
S57 Crushing injury of forearm	0.537	0.463	0.000
S55 Injury of blood vessels at forearm level	0.537	0.463	0.000
S54 Injury of nerves at forearm level	0.537	0.463	0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.537	0.463	0.000
T91.3 Sequelae of injury of spinal cord	0.536	0.464	0.000
T31 Burns classified according to extent of body surface involved	0.535	0.465	0.000
S10 Superficial injury of neck	0.534	0.465	0.000
T36.0 Penicillins	0.534	0.466	0.000
S19 Other and unspecified injuries of neck	0.533	0.466	0.001
S82.9 Fracture of lower leg, part unspecified	0.532	0.467	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.532	0.468	0.000
T91.9 Sequelae of unspecified injury of neck and trunk	0.531	0.468	0.000
T91.5 Sequelae of injury of intra-abdominal and pelvic organs	0.531	0.468	0.000
T91.4 Sequelae of injury of intrathoracic organs	0.531	0.468	0.000
T91.0 Sequelae of superficial injury and open wound of neck and trunk	0.531	0.468	0.000
S82.6 Fracture of lateral malleolus	0.531	0.469	0.000
S89.7 Multiple injuries of lower leg	0.531	0.469	0.000
S89.1 Other specified injuries of lower leg	0.531	0.469	0.000
S89.0 Multiple injuries of lower leg	0.531	0.469	0.000
T51.9 Alcohol, unspecified	0.531	0.469	0.000
S82.5 Fracture of medial malleolus	0.528	0.472	0.000
T98.2 Sequelae of certain early complications of trauma	0.528	0.472	0.000
T98.0 Sequelae of effects of foreign body entering through natural orifice	0.528	0.472	0.000
S89.8 Other specified injuries of lower leg	0.527	0.473	0.000
S29.9 Unspecified injury of thorax	0.526	0.474	0.000
S83.7 Injury to multiple structures of knee	0.524	0.476	0.000
S83.3 Tear of articular cartilage of knee, current	0.524	0.476	0.000
S83.1 Dislocation of knee	0.524	0.476	0.000
S83.0 Dislocation of patella	0.524	0.476	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.524	0.476	0.000
T32 Corrosions classified according to extent of body surface involved	0.523	0.477	0.000
T30 Burn and corrosion, body region unspecified	0.523	0.477	0.000
T29 Burns and corrosions of multiple body regions	0.523	0.477	0.000
T36.9 Systemic antibiotic, unspecified	0.522	0.478	0.000
T36.8 Other systemic antibiotics	0.522	0.478	0.000
T36.7 Antifungal antibiotics, systemically used	0.522	0.478	0.000
T36.6 Rifamycins	0.522	0.478	0.000
T36.5 Aminoglycosides	0.522	0.478	0.000
T36.4 Tetracyclines	0.522	0.478	0.000
T36.3 Macrolides	0.522	0.478	0.000
T36.2 Chloramphenicol group	0.522	0.478	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.522	0.478	0.000
S27.0 Traumatic pneumothorax	0.522	0.478	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.521	0.478	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.521	0.478	0.000
T47.7 Emetics	0.521	0.478	0.000
T47.6 Antidiarrhoeal drugs	0.521	0.478	0.000
T47.5 Digestants	0.521	0.478	0.000
T47.4 Other laxatives	0.521	0.478	0.000
T47.3 Saline and osmotic laxatives	0.521	0.478	0.000
T47.2 Stimulant laxatives	0.521	0.478	0.000
T47.0 Histamine H(2)-receptor antagonists	0.521	0.478	0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.519	0.481	0.000
T98.1 Sequelae of other and unspecified effects of external causes	0.519	0.481	0.000
T87.5 Necrosis of amputation stump	0.519	0.481	0.000
T87.3 Neuroma of amputation stump	0.519	0.481	0.000
T87.2 Complications of other reattached body part	0.519	0.481	0.000
T87.1 Complications of reattached (part of) lower extremity	0.519	0.481	0.000
T87.0 Complications of reattached (part of) upper extremity	0.519	0.481	0.000
T23.0 Burn of unspecified degree of wrist and hand	0.515	0.485	0.000
T28 Burn and corrosion of other internal organs	0.514	0.486	0.000
T27 Burn and corrosion of respiratory tract	0.514	0.486	0.000
T26 Burn and corrosion confined to eye and adnexa	0.514	0.486	0.000
T35 Frostbite involving multiple body regions and unspecified frostbite	0.514	0.486	0.000
T34 Frostbite with tissue necrosis	0.514	0.486	0.000
T33 Superficial frostbite	0.514	0.486	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.514	0.486	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.514	0.486	0.000
T37.5 Antiviral drugs	0.514	0.486	0.000
T37.4 Anthelminthics	0.514	0.486	0.000
T37.3 Other antiprotozoal drugs	0.514	0.486	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.514	0.486	0.000
T37.1 Antimycobacterial drugs	0.514	0.486	0.000
T37.0 Sulphonamides	0.514	0.486	0.000
T41.5 Therapeutic gases	0.514	0.486	0.000
T41.4 Anaesthetic, unspecified	0.514	0.486	0.000
T41.3 Local anaesthetics	0.514	0.486	0.000
T41.2 Other and unspecified general anaesthetics	0.514	0.486	0.000
T41.1 Intravenous anaesthetics	0.514	0.486	0.000
T41.0 Inhaled anaesthetics	0.514	0.486	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.514	0.486	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.514	0.486	0.000
T48.5 Anti-common-cold drugs	0.514	0.486	0.000
T48.4 Expectorants	0.514	0.486	0.000
T48.3 Antitussives	0.514	0.486	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.514	0.486	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.514	0.486	0.000
T48.0 Oxytocic drugs	0.514	0.486	0.000
T49.9 Topical agent, unspecified	0.514	0.486	0.000
T49.8 Other topical agents	0.514	0.486	0.000
T49.7 Dental drugs, topically applied	0.514	0.486	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.514	0.486	0.000
T49.5 Ophthalmological drugs and preparations	0.514	0.486	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.514	0.486	0.000
T49.3 Emollients, demulcents and protectants	0.514	0.486	0.000
T49.2 Local astringents and local detergents	0.514	0.486	0.000
T49.1 Antipruritics	0.514	0.486	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.514	0.486	0.000
T66 Unspecified effects of radiation	0.512	0.488	0.000
S27.2 Traumatic heamopneumothorax	0.510	0.489	0.000
S13.4 Sprain and strain of cervical spine	0.510	0.490	0.000
S84.9 Injury of unspecified nerve at lower leg level	0.510	0.490	0.000
S84.8 Injury of other nerves at lower leg level	0.510	0.490	0.000
S84.7 Injury of multiple nerves at lower leg level	0.510	0.490	0.000
S84.2 Injury of cutaneous sensory nerve at lower leg level	0.510	0.490	0.000
S84.1 Injury of peroneal nerve at lower leg level	0.510	0.490	0.000
S84.0 Injury of tibial nerve at lower leg level	0.510	0.490	0.000
S85.9 Injury of unspecified blood vessel at lower leg level	0.510	0.490	0.000
S85.8 Injury of other blood vessels at lower leg level	0.510	0.490	0.000
S85.7 Injury of multiple blood vessels at lower leg level	0.510	0.490	0.000
S85.5 Injury of popliteal vein	0.510	0.490	0.000
S85.4 Injury of lesser saphenous vein at lower leg level	0.510	0.490	0.000
S85.3 Injury of greater saphenous vein at lower leg level	0.510	0.490	0.000
S85.2 Injury of peroneal artery	0.510	0.490	0.000
S85.1 Injury of (anterior)(posterior) tibial artery	0.510	0.490	0.000
S85.0 Injury of popliteal artery	0.510	0.490	0.000
S87.8 Crushing injury of other and unspecified parts of lower leg	0.510	0.490	0.000
S87.0 Crushing injury of knee	0.510	0.490	0.000
S88.9 Traumatic amputation of lower leg, level unspecified	0.510	0.490	0.000
S88.1 Traumatic amputation at level between knee and ankle	0.510	0.490	0.000
S88.0 Traumatic amputation at knee level	0.510	0.490	0.000
S20.7 Multiple superficial injuries of thorax	0.508	0.492	0.000
S20.4 Other superficial injuries of back wall of thorax	0.508	0.492	0.000
S20.1 Other and unspecified superficial injuries of breast	0.508	0.492	0.000
S20.0 Contusion of breast	0.508	0.492	0.000
S56 Injury of muscle and tendon at forearm level	0.508	0.492	0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.507	0.493	0.000
S12.90 Fracture of neck, part unspecified (closed)	0.507	0.493	0.000
T20.0 Burn of unspecified degree of head and neck	0.506	0.494	0.000
T87.6 Other and unspecified complications of amputation stump	0.505	0.495	0.000
S27.1 Traumatic haemothorax	0.505	0.495	0.000
S14.6 Injury of other and unspecified nerves of neck	0.504	0.495	0.000
S14.5 Injury of cervical sympathetic nerves	0.504	0.495	0.000
S14.4 Injury of peripheral nerves of neck	0.504	0.495	0.000
S14.3 Injury of brachial plexus	0.504	0.495	0.000
S14.2 Injury of nerve root of cervical spine	0.504	0.495	0.000
S14.0 Concussion and oedema of cervical spinal cord	0.504	0.495	0.000
T59.9 Gases, fumes and vapours, unspecified	0.502	0.498	0.000
T59.7 Carbon dioxide	0.502	0.498	0.000
T59.6 Hydrogen sulphide	0.502	0.498	0.000
T59.5 Fluorine gas and hydrogen fluoride	0.502	0.498	0.000
T59.4 Chlorine gas	0.502	0.498	0.000
T59.3 Lachrymogenic gas	0.502	0.498	0.000
T59.2 Formaldehyde	0.502	0.498	0.000
T59.1 Sulphur dioxide	0.502	0.498	0.000
T59.0 Nitrogen oxides	0.502	0.498	0.000
T75 Effects of other external causes	0.501	0.498	0.000
T74 Maltreatment syndromes	0.501	0.498	0.000
T73 Effects of other deprivation	0.501	0.498	0.000
T70 Effects of air pressure and water pressure	0.501	0.498	0.000
T69 Other effects of reduced temperature	0.501	0.498	0.000
T67 Effects of heat and light	0.501	0.498	0.000
T22.3 Burn of third degree of shoulder and upper limb, except wrist and hand	0.501	0.499	0.000
S00 Superficial injury of head	0.498	0.502	0.000
S51.0 Open wound of elbow	0.496	0.504	0.000
T94.1 Sequelae of injuries, not specified by body region	0.495	0.505	0.000
S12.71 Multiple fractures of cervical spine (open)	0.493	0.506	0.000
T88.4 Failed or difficult intubation	0.493	0.507	0.000
T94.0 Sequelae of injuries involving multiple body regions	0.493	0.507	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.492	0.508	0.000
T78.2 Anaphylactic shock, unspecified	0.491	0.509	0.000
S51.8 Open wound of other parts of forearm	0.489	0.511	0.000
S82.11 Fracture of upper end of tibia (open)	0.488	0.512	0.000
S27.3 Other injuries of lung	0.488	0.512	0.000
S27.9 Injury of unspecified intrathoracic organ	0.486	0.514	0.000
S27.8 Injury of other specified intrathoracic organs	0.486	0.514	0.000
S27.7 Multiple injuries of intrathoracic organs	0.486	0.514	0.000
S27.6 Injury of pleura	0.486	0.514	0.000
S27.5 Injury of thoracic trachea	0.486	0.514	0.000
S27.4 Injury of bronchus	0.486	0.514	0.000
S50.8 Other superficial injuries of forearm	0.485	0.515	0.000
T58 Toxic effect of carbon monoxide	0.484	0.516	0.000
S82.4 Fracture of fibula alone	0.480	0.520	0.000
T01.9 Multiple open wounds, unspecified	0.478	0.522	0.000
T01.6 Open wounds involving multiple regions of upper limb(s) with lower limb(s)	0.478	0.522	0.000
T01.3 Open wounds involving multiple regions of lower limb(s)	0.478	0.522	0.000
T01.2 Open wounds involving multiple regions of upper limb(s)	0.478	0.522	0.000
T01.1 Open wounds involving thorax with abdomen, lower back and pelvis	0.478	0.522	0.000
T01.0 Open wounds involving head with neck	0.478	0.522	0.000
S59.9 Unspecified injury of forearm	0.475	0.524	0.000
S12.10 Fracture of second cervical vertebra (closed)	0.474	0.526	0.000
S29.8 Other specified injuries of thorax	0.473	0.527	0.000
S29.7 Multiple injuries of thorax	0.473	0.527	0.000
S29.0 Injury of muscle and tendon at thorax level	0.473	0.527	0.000
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand	0.473	0.527	0.000
T00.3 Superficial injuries involving multiple regions of lower limb(s)	0.471	0.529	0.000
S41 Open wound of shoulder and upper arm	0.470	0.529	0.000
T86.1 Kidney transplant failure and rejection	0.467	0.532	0.000
T20.1 Burn of first degree of head and neck	0.467	0.533	0.000
S11.9 Open wound of neck, part unspecified	0.467	0.533	0.000
S11.8 Open wound of other parts of neck	0.467	0.533	0.000
S11.7 Multiple open wounds of neck	0.467	0.533	0.000
S11.2 Open wound involving pharynx and cervical oesophagus	0.467	0.533	0.000
S11.1 Open wound involving thyroid gland	0.467	0.533	0.000
S11.0 Open wound involving larynx and trachea	0.467	0.533	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations