TreeWAS – Variant ID: rs11651885

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I25.9 Chronic ischaemic heart disease, unspecified	0.000	0.001	0.999
I25 Chronic ischaemic heart disease	0.000	0.013	0.987
I25.2 Old myocardial infarction	0.000	0.017	0.983
I25.1 Atherosclerotic heart disease	0.000	0.050	0.950
I25.0 Atherosclerotic cardiovascular disease, so described	0.000	0.179	0.821
I25.3 Aneurysm of heart	0.000	0.347	0.653
I25.6 Silent myocardial ischaemia	0.000	0.374	0.626
I25.5 Ischaemic cardiomyopathy	0.000	0.418	0.582
I25.4 Coronary artery aneurysm	0.000	0.436	0.564
I20-I25 Ischaemic heart diseases	0.000	0.715	0.285
I20.9 Angina pectoris, unspecified	0.000	0.717	0.283
I20 Angina pectoris	0.000	0.725	0.275
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.000	0.735	0.265
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.000	0.758	0.242
C85.1 B-cell lymphoma, unspecified	0.000	0.768	0.232
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.000	0.818	0.182
I23 Certain current complications following acute myocardial infarction	0.000	0.820	0.180
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.000	0.820	0.180
I24 Other acute ischaemic heart diseases	0.000	0.825	0.175
C84 Peripheral and cutaneous T-cell lymphomas	0.000	0.827	0.173
I20.8 Other forms of angina pectoris	0.000	0.830	0.170
C92 Myeloid leukaemia	0.000	0.831	0.169
C85.0 Lymphosarcoma	0.000	0.839	0.160
C84.5 Other and unspecified T-cell lymphomas	0.000	0.842	0.158
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.843	0.157
C84.4 Peripheral T-cell lymphoma	0.000	0.843	0.157
C92.0 Acute myeloid leukaemia	0.000	0.844	0.156
I25.8 Other forms of chronic ischaemic heart disease	0.000	0.855	0.145
C92.4 Acute promyelocytic leukaemia	0.000	0.855	0.145
C83 Diffuse non-Hodgkin's lymphoma	0.000	0.863	0.137
H40.1 Primary open-angle glaucoma	0.000	0.863	0.137
C94 Other leukaemias of specified cell type	0.000	0.866	0.134
I20.1 Angina pectoris with documented spasm	0.000	0.866	0.134
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.000	0.869	0.131
C85.7 Other specified types of non-Hodgkin's lymphoma	0.000	0.869	0.130
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.000	0.870	0.129
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.000	0.870	0.129
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.000	0.870	0.129
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.000	0.870	0.129
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.000	0.870	0.129
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.000	0.870	0.129
C92.9 Myeloid leukaemia, unspecified	0.000	0.872	0.128
C93 Monocytic leukaemia	0.000	0.872	0.127
I24.1 Dressler's syndrome	0.000	0.872	0.127
C86 Other specified types of T/NK-cell lymphoma	0.000	0.873	0.127
C84.0 Mycosis fungoides	0.000	0.874	0.126
H40 Glaucoma	0.000	0.875	0.125
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.000	0.875	0.125
C84.9 Mature T/NK-cell lymphoma, unspecified	0.000	0.875	0.124
C84.7 Anaplastic large cell lymphoma, ALK-negative	0.000	0.875	0.124
C84.6 Anaplastic large cell lymphoma, ALK-positive	0.000	0.875	0.124
C84.3 Lymphoepithelioid lymphoma	0.000	0.875	0.124
C84.2 T-zone lymphoma	0.000	0.875	0.124
C84.1 Sezary's diease	0.000	0.875	0.124
C88 Malignant immunoproliferative diseases	0.000	0.878	0.122
C92.8 Acute myeloid leukaemia with multilineage dysplasia	0.000	0.878	0.121
C92.6 Acute myeloid leukaemia with 11q23-abnormality	0.000	0.878	0.121
C92.3 Myeloid sarcoma	0.000	0.878	0.121
C92.2 Subacute myeloid leukaemia	0.000	0.878	0.121
C81 Hodgkin's disease	0.000	0.879	0.121
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.000	0.880	0.119
I23.8 Other current complications following acute myocardial infarction	0.000	0.883	0.117
H40.2 Primary angle-closure glaucoma	0.000	0.884	0.116
C95 Leukaemia of unspecified cell type	0.000	0.884	0.116
C92.5 Acute myelomonocytic leukaemia	0.000	0.885	0.115
C92.7 Other myeloid leukaemia	0.000	0.886	0.114
H40.8 Other glaucoma	0.000	0.887	0.113
C83.1 Small cleaved cell (diffuse)	0.000	0.888	0.112
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.000	0.888	0.112
C84.8 Cutaneous T-cell lymphoma, unspecified	0.000	0.889	0.111
C83.3 Large cell (diffuse)	0.000	0.889	0.111
C92.1 Chronic myeloid leukaemia	0.000	0.889	0.111
C91 Lymphoid leukaemia	0.000	0.892	0.108
H40.5 Glaucoma secondary to other eye disorders	0.000	0.893	0.107
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.000	0.898	0.102
C82.3 Follicular lymphoma grade IIIa	0.000	0.900	0.100
C94.4 Acute panmyelosis	0.000	0.901	0.099
C83.6 Undifferentiated (diffuse)	0.000	0.901	0.099
C83.4 Immunoblastic (diffuse)	0.000	0.901	0.099
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified	0.000	0.902	0.097
C83.5 Lymphoblastic (diffuse)	0.000	0.902	0.097
C94.7 Other specified leukaemias	0.000	0.903	0.096
C94.5 Acute myelofibrosis	0.000	0.903	0.096
C94.3 Mast cell leukaemia	0.000	0.903	0.096
C94.2 Acute megakaryoblastic leukaemia	0.000	0.903	0.096
C94.1 Chronic erythraemia	0.000	0.903	0.096
C94.0 Acute erythraemia and erythroleukaemia	0.000	0.903	0.096
C83.7 Burkitt's tumour	0.000	0.904	0.096
C83.2 Mixed small and large cell (diffuse)	0.000	0.904	0.095
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified	0.000	0.906	0.094
C96.8 Histiocytic sarcoma	0.000	0.906	0.094
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.000	0.906	0.094
C96.6 Unifocal Langerhans-cell histiocytosis	0.000	0.906	0.094
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis	0.000	0.906	0.094
C96.4 Sarcoma of dendritic cells (accessory cells)	0.000	0.906	0.094
C96.3 True histiocytic lymphoma	0.000	0.906	0.094
C96.2 Malignant mast cell tumour	0.000	0.906	0.094
C96.1 Malignant histiocytosis	0.000	0.906	0.094
C96.0 Letterer-Siwe disease	0.000	0.906	0.094
H40.4 Glaucoma secondary to eye inflammation	0.000	0.907	0.093
C81.1 Nodular sclerosis	0.000	0.907	0.093
C82.4 Follicular lymphoma grade IIIb	0.000	0.907	0.093
C93.9 Monocytic leukaemia, unspecified	0.000	0.908	0.091
C93.7 Other monocytic leukaemia	0.000	0.908	0.091
C93.3 Juvenile myelomonocytic leukaemia	0.000	0.908	0.091
C93.2 Subacute monocytic leukaemia	0.000	0.908	0.091
C93.0 Acute monocytic leukaemia	0.000	0.908	0.091
C82.0 Small cleaved cell, follicular	0.000	0.909	0.091
C86.6 Primary cutaneous CD30-positive T-cell proliferations	0.000	0.909	0.091
C86.4 Blastic NK-cell lymphoma	0.000	0.909	0.091
C86.3 Subcutaneous panniculitis-like T-cell lymphoma	0.000	0.909	0.091
C86.2 Enteropathy-type (intestinal) T-cell lymphoma	0.000	0.909	0.091
C86.1 Hepatosplenic T-cell lymphoma	0.000	0.909	0.091
C86.0 Extranodal NK/T-cell lymphoma, nasal type	0.000	0.909	0.091
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]	0.000	0.909	0.090
C91.9 Lymphoid leukaemia, unspecified	0.000	0.909	0.090
C82.6 Cutaneous follicle centre lymphoma	0.000	0.910	0.089
C82.5 Diffuse follicle centre lymphoma	0.000	0.910	0.089
I24.8 Other forms of acute ischaemic heart disease	0.000	0.911	0.089
H40.0 Glaucoma suspect	0.000	0.911	0.089
C93.1 Chronic monocytic leukaemia	0.000	0.911	0.088
C81.7 Other Hodgkin's disease	0.000	0.912	0.088
I20.0 Unstable angina	0.000	0.912	0.088
C88.9 Malignant immunoproliferative disease, unspecified	0.000	0.912	0.088
C88.7 Other malignant immunoproliferative diseases	0.000	0.912	0.088
C88.3 Immunoproliferative small intestinal disease	0.000	0.912	0.088
C88.2 Gamma heavy chain disease	0.000	0.912	0.088
C88.1 Alpha heavy chain disease	0.000	0.912	0.088
C86.5 Angioimmunoblastic T-cell lymphoma	0.000	0.913	0.087
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.000	0.913	0.087
C81.3 Lymphocytic depletion	0.000	0.913	0.087
C81.9 Hodgkin's disease, unspecified	0.000	0.913	0.087
C95.9 Leukaemia, unspecified	0.000	0.914	0.086
H40.3 Glaucoma secondary to eye trauma	0.000	0.915	0.085
C83.0 Small cell (diffuse)	0.000	0.915	0.084
C91.4 Hairy-cell leukaemia	0.000	0.916	0.084
C95.7 Other leukaemia of unspecified cell type	0.000	0.916	0.083
C95.2 Subacute leukaemia of unspecified cell type	0.000	0.916	0.083
H40.6 Glaucoma secondary to drugs	0.000	0.917	0.083
C90 Multiple myeloma and malignant plasma cell neoplasms	0.000	0.918	0.082
C81.0 Lymphocytic predominance	0.000	0.919	0.081
C82.2 Large cell, follicular	0.000	0.922	0.078
C91.5 Adult T-cell leukaemia	0.000	0.922	0.078
C91.8 Mature B-cell leukaemia Burkitt-type	0.000	0.922	0.078
C91.7 Other lymphoid leukaemia	0.000	0.922	0.078
C91.6 Prolymphocytic leukaemia of T-cell type	0.000	0.922	0.078
C91.3 Prolymphocytic leukaemia	0.000	0.922	0.078
C91.2 Subacute lymphocytic leukaemia	0.000	0.922	0.078
C81.2 Mixed cellularity	0.000	0.923	0.076
C95.1 Chronic leukaemia of unspecified cell type	0.000	0.923	0.076
C88.0 Waldenstrom's macroglobulinaemia	0.000	0.924	0.076
C95.0 Acute leukaemia of unspecified cell type	0.000	0.926	0.074
C82.1 Mixed small cleaved and large cell, follicular	0.000	0.928	0.072
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.000	0.929	0.070
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.000	0.929	0.070
C91.0 Acute lymphoblastic leukaemia	0.000	0.931	0.069
I22 Subsequent myocardial infarction	0.000	0.931	0.069
C90.1 Plasma cell leukaemia	0.000	0.939	0.060
C90.3 Solitary plasmacytoma	0.000	0.942	0.058
H40-H42 Glaucoma	0.000	0.947	0.053
K62.3 Rectal prolapse	0.000	0.948	0.052
I21 Acute myocardial infarction	0.000	0.949	0.051
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.950	0.050
C90.2 Plasmacytoma, extramedullary	0.000	0.951	0.049
H40.9 Glaucoma, unspecified	0.000	0.953	0.047
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.956	0.044
I22.8 Subsequent myocardial infarction of other sites	0.000	0.956	0.043
I69.3 Sequelae of cerebral infarction	0.000	0.957	0.043
I69 Sequelae of cerebrovascular disease	0.000	0.958	0.042
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.960	0.040
H42 Glaucoma in diseases classified elsewhere	0.000	0.962	0.038
Z87.2 Personal history of diseases of the skin and subcutaneous tissue	0.000	0.962	0.038
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.962	0.038
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.963	0.037
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.963	0.037
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.964	0.036
I21.4 Acute subendocardial myocardial infarction	0.000	0.965	0.035
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.966	0.034
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.967	0.033
C90.0 Multiple myeloma	0.000	0.967	0.033
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.000	0.970	0.030
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.000	0.971	0.029
H42.8 Glaucoma in other diseases classified elsewhere	0.000	0.972	0.027
H42.0 Glaucoma in endocrine, nutritional and metabolic diseases	0.000	0.972	0.027
I21.9 Acute myocardial infarction, unspecified	0.000	0.975	0.025
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.977	0.023
Z90.1 Acquired absence of breast(s)	0.000	0.977	0.023
F40.2 Specific (isolated) phobias	0.000	0.979	0.021
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.979	0.021
C91.1 Chronic lymphocytic leukaemia	0.000	0.981	0.019
Z87.8 Personal history of other specified conditions	0.000	0.984	0.016
F40 Phobic anxiety disorders	0.000	0.988	0.012
G47.9 Sleep disorder, unspecified	0.012	0.988	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.000	0.988	0.012
Z71.8 Other specified counselling	0.000	0.988	0.012
H65 Nonsuppurative otitis media	0.000	0.988	0.012
E78.5 Hyperlipidaemia, unspecified	0.000	0.989	0.011
F40.9 Phobic anxiety disorder, unspecified	0.000	0.989	0.011
H65.3 Chronic mucoid otitis media	0.000	0.989	0.011
H65.4 Other chronic nonsuppurative otitis media	0.000	0.989	0.011
Z87 Personal history of other diseases and conditions	0.000	0.989	0.011
F40.8 Other phobic anxiety disorders	0.000	0.990	0.010
H65.2 Chronic serous otitis media	0.000	0.990	0.010
H65.1 Other acute nonsuppurative otitis media	0.000	0.990	0.010
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium	0.000	0.991	0.009
F40.1 Social phobias	0.000	0.991	0.009
H65.0 Acute serous otitis media	0.000	0.991	0.008
Z87.6 Personal history of certain conditions arising in the perinatal period	0.000	0.992	0.008
F40.0 Agoraphobia	0.000	0.992	0.007
S83.2 Tear of meniscus, current	0.007	0.993	0.000
Z95.4 Presence of other heart-valve replacement	0.000	0.993	0.007
N92.6 Irregular menstruation, unspecified	0.007	0.993	0.000
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue	0.000	0.994	0.006
R52.1 Chronic intractable pain	0.006	0.994	0.000
K05.3 Chronic periodontitis	0.006	0.994	0.000
J35.1 Hypertrophy of tonsils	0.000	0.995	0.005
Z86.5 Personal history of other mental and behavioural disorders	0.005	0.995	0.000
G47 Sleep disorders	0.005	0.995	0.000
I50.0 Congestive heart failure	0.000	0.995	0.005
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.000	0.995	0.005
O03.9 Complete or unspecified, without complication	0.000	0.995	0.005
Z42.1 Follow-up care involving plastic surgery of breast	0.000	0.995	0.005
R52.2 Other chronic pain	0.005	0.995	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.005	0.995	0.000
R52 Pain, not elsewhere classified	0.005	0.995	0.000
S42.00 Fracture of clavicle (closed)	0.000	0.995	0.005
G47.2 Disorders of the sleep-wake schedule	0.005	0.995	0.000
G47.1 Disorders of excessive somnolence [hypersomnias]	0.004	0.996	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.004	0.996	0.000
J39.2 Other diseases of pharynx	0.004	0.996	0.000
S83.7 Injury to multiple structures of knee	0.004	0.996	0.000
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities	0.000	0.996	0.004
G47.4 Narcolepsy and cataplexy	0.004	0.996	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.004	0.996	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.996	0.004
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.000	0.996	0.004
R52.0 Acute pain	0.004	0.996	0.000
S83.1 Dislocation of knee	0.004	0.996	0.000
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.000	0.996	0.004
Q51.3 Bicornate uterus	0.000	0.996	0.004
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.004	0.996	0.000
R73.0 Abnormal glucose tolerance test	0.000	0.996	0.004
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.000	0.996	0.004
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.004	0.996	0.000
R52.9 Pain, unspecified	0.004	0.996	0.000
R40.2 Coma, unspecified	0.000	0.996	0.004
X63.0 Home	0.000	0.996	0.003
S83.3 Tear of articular cartilage of knee, current	0.003	0.997	0.000
G47.3 Sleep apnoea	0.003	0.997	0.000
M21.4 Flat foot [pes planus] (acquired)	0.000	0.997	0.003
S83.0 Dislocation of patella	0.003	0.997	0.000
H16.0 Corneal ulcer	0.000	0.997	0.003
M21 Other acquired deformities of limbs	0.000	0.997	0.003
Q61.2 Polycystic kidney, adult type	0.000	0.997	0.003
G47.8 Other sleep disorders	0.003	0.997	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.997	0.003
H47.2 Optic atrophy	0.000	0.997	0.003
M21.1 Varus deformity, not elsewhere classified	0.000	0.997	0.003
M21.8 Other specified acquired deformities of limbs	0.000	0.997	0.003
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.000	0.997	0.003
M21.59 Acquired clawhand, clubhand, clawfoot and clubfoot-Site uns	0.000	0.997	0.003
M21.58 Acquired clawhand, clubhand, clawfoot and clubfoot-Other	0.000	0.997	0.003
M21.56 Acquired clawhand, clubhand, clawfoot and clubfoot-Lower le	0.000	0.997	0.003
M21.55 Acquired clawhand, clubhand, clawfoot and clubfoot-Pelvic/t	0.000	0.997	0.003
M21.53 Acquired clawhand, clubhand, clawfoot and clubfoot-Forearm	0.000	0.997	0.003
M21.52 Acquired clawhand, clubhand, clawfoot and clubfoot-Upper ar	0.000	0.997	0.003
M21.51 Acquired clawhand, clubhand, clawfoot and clubfoot-Shldr re	0.000	0.997	0.003
M21.50 Acquired clawhand, clubhand, clawfoot and clubfoot (Multiple sites)	0.000	0.997	0.003
M21.3 Wrist or foot drop (acquired)	0.000	0.997	0.003
M21.83 Other specified acquired deformities of limbs (Forearm)	0.000	0.997	0.003
G47.0 Disorders of initiating and maintaining sleep [insomnias]	0.003	0.997	0.000
J39 Other diseases of upper respiratory tract	0.003	0.997	0.000
M21.7 Unequal limb length (acquired)	0.000	0.997	0.003
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.003	0.997	0.000
S83.6 Sprain and strain of other and unspecified parts of knee	0.003	0.997	0.000
M21.86 Other specified acquired deformities of limbs (Lower leg)	0.000	0.997	0.003
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.997	0.003
J39.8 Other specified diseases of upper respiratory tract	0.003	0.997	0.000
N20.2 Calculus of kidney with calculus of ureter	0.003	0.997	0.000
M21.87 Other specified acquired deformities of limbs (Ankle and foot)	0.000	0.997	0.003
I11 Hypertensive heart disease	0.000	0.997	0.003
M21.49 Flat foot [pes planus] (acquired)-Site unspec	0.000	0.997	0.003
M21.48 Flat foot [pes planus] (acquired)-Other	0.000	0.997	0.003
M21.46 Flat foot [pes planus] (acquired)-Lower leg	0.000	0.997	0.003
M21.45 Flat foot [pes planus] (acquired)-Pelvic/thigh	0.000	0.997	0.003
M21.44 Flat foot [pes planus] (acquired)-Hand	0.000	0.997	0.003
M21.43 Flat foot [pes planus] (acquired)-Forearm	0.000	0.997	0.003
M21.42 Flat foot [pes planus] (acquired)-Upper arm	0.000	0.997	0.003
M21.41 Flat foot [pes planus] (acquired)-Shldr region	0.000	0.997	0.003
M21.40 Flat foot [pes planus] (acquired)-Mult sites	0.000	0.997	0.003
M21.54 Acquired clawhand, clubhand, clawfoot and clubfoot (Hand)	0.000	0.997	0.003
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)	0.000	0.997	0.003
J39.1 Other abscess of pharynx	0.003	0.997	0.000
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.000	0.997	0.002
M21.18 Varus deformity, not elsewhere classified (Other)	0.000	0.997	0.002
M21.14 Varus deformity, not elsewhere classified (Hand)	0.000	0.997	0.002
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.000	0.997	0.002
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.000	0.997	0.002
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.000	0.997	0.002
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.000	0.997	0.002
H47.0 Disorders of optic nerve, not elsewhere classified	0.000	0.997	0.003
M21.89 Other specified acquired deformities of limbs (Site unspecified)	0.000	0.997	0.002
M21.88 Other specified acquired deformities of limbs-Other	0.000	0.997	0.002
M21.84 Other specified acquired deformities of limbs (Hand)	0.000	0.997	0.002
M21.82 Other specified acquired deformities of limbs (Upper arm)	0.000	0.997	0.002
M21.81 Other specified acquired deformities of limbs (Shoulder region)	0.000	0.997	0.002
M21.80 Other specified acquired deformities of limbs (Multiple sites)	0.000	0.997	0.002
M21.76 Unequal limb length (acquired) (Lower leg)	0.000	0.997	0.003
M23.43 Loose body in knee-Med lig/oth men	0.000	0.997	0.003
M21.9 Acquired deformity of limb, unspecified	0.000	0.997	0.002
Y51 Drugs primarily affecting the autonomic nervous system	0.003	0.997	0.000
J39.9 Disease of upper respiratory tract, unspecified	0.002	0.997	0.000
M21.6 Other acquired deformities of ankle and foot	0.000	0.997	0.002
M21.2 Flexion deformity	0.000	0.997	0.002
M21.85 Other specified acquired deformities of limbs (Pelvic region and thigh)	0.000	0.997	0.002
M21.39 Wrist or foot drop (acquired)-Site unspec	0.000	0.997	0.002
M21.38 Wrist or foot drop (acquired)-Other	0.000	0.997	0.002
M21.36 Wrist or foot drop (acquired)-Lower leg	0.000	0.997	0.002
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.000	0.997	0.002
M21.34 Wrist or foot drop (acquired) (Hand)	0.000	0.997	0.002
M21.32 Wrist or foot drop (acquired)-Upper arm	0.000	0.997	0.002
M21.31 Wrist or foot drop (acquired)-Shldr region	0.000	0.997	0.002
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.000	0.997	0.002
C69.3 Choroid	0.000	0.997	0.002
Q61 Cystic kidney disease	0.000	0.997	0.003
Q61.0 Congenital single renal cyst	0.000	0.998	0.002
H47 Other disorders of optic [2nd] nerve and visual pathways	0.000	0.998	0.002
J39.3 Upper respiratory tract hypersensitivity reaction, site unspecified	0.002	0.998	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.002	0.998	0.000
O03 Spontaneous abortion	0.000	0.998	0.002
M21.25 Flexion deformity (Pelvic region and thigh)	0.000	0.998	0.002
M21.79 Unequal limb length (acquired) (Site unspecified)	0.000	0.998	0.002
M21.78 Unequal limb length (acquired)-Other	0.000	0.998	0.002
M21.77 Unequal limb length (acquired) (Ankle and foot)	0.000	0.998	0.002
M21.75 Unequal limb length (acquired) (Pelvic region and thigh)	0.000	0.998	0.002
M21.74 Unequal limb length (acquired) (Hand)	0.000	0.998	0.002
M21.72 Unequal limb length (acquired) (Upper arm)	0.000	0.998	0.002
M21.71 Unequal limb length (acquired)-Shldr region	0.000	0.998	0.002
M21.70 Unequal limb length (acquired) (Multiple sites)	0.000	0.998	0.002
M23.49 Loose body in knee-Unspec lig/men	0.000	0.998	0.002
H65-H75 Diseases of middle ear and mastoid	0.000	0.998	0.002
S82.10 Fracture of upper end of tibia (closed)	0.000	0.998	0.002
J39.0 Retropharyngeal and parapharyngeal abscess	0.002	0.998	0.000
Q60.0 Renal agenesis, unilateral	0.000	0.998	0.002
H71 Cholesteatoma of middle ear	0.000	0.998	0.002
M21.73 Unequal limb length (acquired) (Forearm)	0.000	0.998	0.002
Y52.4 Angiotensin-converting-enzyme inhibitors	0.002	0.998	0.000
M23.4 Loose body in knee	0.000	0.998	0.002
M23.44 Loose body in knee-Lat lig/ant men	0.000	0.998	0.002
M21.33 Wrist or foot drop (acquired) (Forearm)	0.000	0.998	0.002
Q60 Renal agenesis and other reduction defects of kidney	0.000	0.998	0.002
D23.5 Skin of trunk	0.002	0.998	0.000
H43.8 Other disorders of vitreous body	0.000	0.998	0.002
K35.0 Acute appendicitis with generalised peritonitis	0.000	0.998	0.002
M21.96 Acquired deformity of limb, unspecified (Lower leg)	0.000	0.998	0.002
H70 Mastoiditis and related conditions	0.000	0.998	0.002
M21.26 Flexion deformity (Lower leg)	0.000	0.998	0.002
Y53.1 Other antacids and anti-gastric-secretion drugs	0.002	0.998	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.002	0.998	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.002	0.998	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.002	0.998	0.000
Y51.0 Anticholinesterase agents	0.002	0.998	0.000
M21.99 Acquired deformity of limb, unspecified (Site unspecified)	0.000	0.998	0.002
M21.98 Acquired deformity of limb, unspecified-Other	0.000	0.998	0.002
M21.95 Acquired deformity of limb, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
M21.93 Acquired deformity of limb, unspecified (Forearm)	0.000	0.998	0.002
M21.92 Acquired deformity of limb, unspecified (Upper arm)	0.000	0.998	0.002
M21.91 Acquired deformity of limb, unspecified (Shoulder region)	0.000	0.998	0.002
M21.90 Acquired deformity of limb, unspecified (Multiple sites)	0.000	0.998	0.002
M23.46 Loose body in knee-O/unsp lat men	0.000	0.998	0.002
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.002	0.998	0.000
Z42 Follow-up care involving plastic surgery	0.000	0.998	0.002
M21.29 Flexion deformity (Site unspecified)	0.000	0.998	0.002
M21.28 Flexion deformity (Other)	0.000	0.998	0.002
M21.23 Flexion deformity (Forearm)	0.000	0.998	0.002
M21.21 Flexion deformity (Shoulder region)	0.000	0.998	0.002
M21.69 Other acquired deformities of ankle and foot-Site unspec	0.000	0.998	0.002
M21.68 Other acquired deformities of ankle and foot-Other	0.000	0.998	0.002
M21.66 Other acquired deformities of ankle and foot-Lower leg	0.000	0.998	0.002
M21.65 Other acquired deformities of ankle and foot-Pelvic/thigh	0.000	0.998	0.002
M21.64 Other acquired deformities of ankle and foot-Hand	0.000	0.998	0.002
M21.63 Other acquired deformities of ankle and foot-Forearm	0.000	0.998	0.002
M21.62 Other acquired deformities of ankle and foot-Upper arm	0.000	0.998	0.002
M21.61 Other acquired deformities of ankle and foot-Shldr region	0.000	0.998	0.002
M21.60 Other acquired deformities of ankle and foot-Mult sites	0.000	0.998	0.002
O03.8 Complete or unspecified, with other and unspecified complications	0.000	0.998	0.002
Z42.3 Follow-up care involving plastic surgery of upper extremity	0.000	0.998	0.002
H20.8 Other iridocyclitis	0.000	0.998	0.002
Q61.8 Other cystic kidney diseases	0.000	0.998	0.002
Q61.1 Polycystic kidney, infantile type	0.000	0.998	0.002
S42.0 Fracture of clavicle	0.000	0.998	0.002
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.000	0.998	0.002
H70.1 Chronic mastoiditis	0.000	0.998	0.002
Y53 Agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
M21.22 Flexion deformity (Upper arm)	0.000	0.998	0.002
M21.20 Flexion deformity (Multiple sites)	0.000	0.998	0.002
O03.3 Incomplete, with other and unspecified complications	0.000	0.998	0.002
M23.40 Loose body in knee-Mult sites	0.000	0.998	0.002
H47.7 Disorder of visual pathways, unspecified	0.000	0.998	0.002
H47.6 Disorders of visual cortex	0.000	0.998	0.002
H47.4 Disorders of optic chiasm	0.000	0.998	0.002
M35.0 Sicca syndrome [Sjogren]	0.002	0.998	0.000
Q60.2 Renal agenesis, unspecified	0.000	0.998	0.002
M21.94 Acquired deformity of limb, unspecified (Hand)	0.000	0.998	0.002
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
M21.97 Acquired deformity of limb, unspecified (Ankle and foot)	0.000	0.998	0.002
H70.9 Mastoiditis, unspecified	0.000	0.998	0.002
O03.7 Complete or unspecified, complicated by embolism	0.000	0.998	0.002
O03.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.000	0.998	0.002
O03.2 Incomplete, complicated by embolism	0.000	0.998	0.002
O03.0 Incomplete, complicated by genital tract and pelvic infection	0.000	0.998	0.002
Q60-Q64 Congenital malformations of the urinary system	0.000	0.998	0.002
H01.0 Blepharitis	0.000	0.998	0.002
Q61.9 Cystic kidney disease, unspecified	0.000	0.998	0.002
Z42.0 Follow-up care involving plastic surgery of head and neck	0.000	0.998	0.002
Q62.3 Other obstructive defects of renal pelvis and ureter	0.000	0.998	0.002
Q62.2 Congenital megaloureter	0.000	0.998	0.002
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.998	0.002
H67 Otitis media in diseases classified elsewhere	0.000	0.998	0.002
O03.1 Incomplete, complicated by delayed or excessive haemorrhage	0.000	0.998	0.002
Q61.5 Medullary cystic kidney	0.000	0.998	0.002
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
C69 Malignant neoplasm of eye and adnexa	0.000	0.998	0.002
H16 Keratitis	0.000	0.998	0.002
H47.5 Disorders of other visual pathways	0.000	0.998	0.002
O03.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.000	0.998	0.002
Q60.3 Renal hypoplasia, unilateral	0.000	0.998	0.002
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
H47.1 Papilloedema, unspecified	0.000	0.998	0.002
N70.1 Chronic salpingitis and oophoritis	0.000	0.998	0.002
Q51 Congenital malformations of uterus and cervix	0.000	0.998	0.002
M23.47 Loose body in knee-Capsular lig	0.000	0.998	0.002
M23.45 Loose body in knee-Pst hrn lat men	0.000	0.998	0.002
M23.42 Loose body in knee-Pst lig/hrn men	0.000	0.998	0.002
Z80.0 Family history of malignant neoplasm of digestive organs	0.002	0.998	0.000
H68 Eustachian salpingitis and obstruction	0.000	0.998	0.002
C69.9 Eye, unspecified	0.000	0.998	0.002
C69.6 Orbit	0.000	0.998	0.002
Q60.6 Potter's syndrome	0.000	0.998	0.002
Q60.5 Renal hypoplasia, unspecified	0.000	0.998	0.002
Q60.4 Renal hypoplasia, bilateral	0.000	0.998	0.002
Q60.1 Renal agenesis, bilateral	0.000	0.998	0.002
Q62.1 Atresia and stenosis of ureter	0.000	0.998	0.002
S61.0 Open wound of finger(s) without damage to nail	0.000	0.998	0.002
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system	0.000	0.998	0.002
Y52 Agents primarily affecting the cardiovascular system	0.002	0.998	0.000
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.000	0.998	0.002
H70.2 Petrositis	0.000	0.998	0.002
L57.0 Actinic keratosis	0.000	0.998	0.002
M21.0 Valgus deformity, not elsewhere classified	0.000	0.998	0.001
Y52.7 Peripheral vasodilators	0.002	0.998	0.000
Y53.4 Other laxatives	0.002	0.998	0.000
H70.8 Other mastoiditis and related conditions	0.000	0.998	0.002
I49.8 Other specified cardiac arrhythmias	0.002	0.998	0.000
Y53.2 Stimulant laxatives	0.002	0.998	0.000
M21.27 Flexion deformity (Ankle and foot)	0.000	0.998	0.002
Q61.4 Renal dysplasia	0.000	0.998	0.002
Z42.2 Follow-up care involving plastic surgery of other parts of trunk	0.000	0.998	0.002
M21.24 Flexion deformity (Hand)	0.000	0.998	0.002
C69.0 Conjunctiva	0.000	0.998	0.002
Y53.6 Antidiarrhoeal drugs	0.002	0.998	0.000
Y53.3 Saline and osmotic laxatives	0.002	0.998	0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.000	0.998	0.002
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.002	0.998	0.000
Z42.8 Follow-up care involving plastic surgery of other body part	0.000	0.998	0.002
R73 Elevated blood glucose level	0.000	0.998	0.002
H70.0 Acute mastoiditis	0.000	0.998	0.002
Q51.8 Other congenital malformations of uterus and cervix	0.000	0.998	0.002
H01 Other inflammation of eyelid	0.000	0.998	0.002
M23.41 Loose body in knee-Ant lig/hrn men	0.000	0.998	0.002
H16.1 Other superficial keratitis without conjunctivitis	0.000	0.998	0.002
Q24.9 Congenital malformation of the heart, unspecified	0.000	0.998	0.002
Q62.7 Congenital vesico-uretero-renal reflux	0.000	0.998	0.002
Q62.6 Malposition of ureter	0.000	0.998	0.002
Q62.4 Agenesis of ureter	0.000	0.998	0.002
Q62.0 Congenital hydronephrosis	0.000	0.998	0.002
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.002	0.998	0.000
Y53.7 Emetics	0.002	0.998	0.000
Y53.5 Digestants	0.002	0.998	0.000
Y53.0 Histamine H2-receptor antagonists	0.002	0.998	0.000
H33.5 Other retinal detachments	0.000	0.998	0.002
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.002	0.998	0.000
H05.2 Exophthalmic conditions	0.000	0.998	0.002
I60-I69 Cerebrovascular diseases	0.000	0.998	0.002
S42.01 Fracture of clavicle (open)	0.000	0.998	0.001
H01.9 Inflammation of eyelid, unspecified	0.000	0.998	0.002
H05.9 Disorder of orbit, unspecified	0.000	0.998	0.002
Q62.8 Other congenital malformations of ureter	0.000	0.998	0.002
Y49.5 Other antipsychotics and neuroleptics	0.002	0.998	0.000
H69 Other disorders of Eustachian tube	0.000	0.998	0.002
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.000	0.998	0.002
C69.4 Ciliary body	0.000	0.998	0.002
H67.8 Otitis media in other diseases classified elsewhere	0.000	0.998	0.001
H67.1 Otitis media in viral diseases classified elsewhere	0.000	0.998	0.001
H67.0 Otitis media in bacterial diseases classified elsewhere	0.000	0.998	0.001
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.998	0.001
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.000	0.998	0.001
N30.1 Interstitial cystitis (chronic)	0.002	0.998	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations