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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs116875324
log Bayes Factor = 0.721333
Chromosome 11   position 121,206,449  (GRCh37) Explore rs116875324 on Ensembl!
Variant rs116875324 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I30-I52 Other forms of heart disease
0.812 0.188 0.000
Chapter IX Diseases of the circulatory system
0.804 0.196 0.000
I35 Nonrheumatic aortic valve disorders
0.787 0.213 0.000
I35.0 Aortic (valve) stenosis
0.773 0.227 0.000
I05-I09 Chronic rheumatic heart diseases
0.757 0.243 0.000
# Top node
0.753 0.247 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.749 0.251 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.745 0.255 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.729 0.271 0.000
I44 Atrioventricular and left bundle-branch block
0.729 0.271 0.000
O00-O08 Pregnancy with abortive outcome
0.721 0.279 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.718 0.282 0.000
Chapter XX External causes of morbidity and mortality
0.714 0.286 0.000
O04 Medical abortion
0.711 0.289 0.000
I51 Complications and ill-defined descriptions of heart disease
0.709 0.291 0.000
I47 Paroxysmal tachycardia
0.698 0.302 0.000
O04.9 Complete or unspecified, without complication
0.698 0.302 0.000
I31 Other diseases of pericardium
0.698 0.302 0.000
I08 Multiple valve diseases
0.693 0.307 0.000
I20-I25 Ischaemic heart diseases
0.676 0.324 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.676 0.324 0.000
I42 Cardiomyopathy
0.672 0.328 0.000
I60-I69 Cerebrovascular diseases
0.670 0.330 0.000
I71 Aortic aneurysm and dissection
0.664 0.336 0.000
I44.2 Atrioventricular block, complete
0.663 0.337 0.000
S60-S69 Injuries to the wrist and hand
0.662 0.338 0.000
I51.9 Heart disease, unspecified
0.659 0.341 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.658 0.342 0.000
Chapter VIII Diseases of the ear and mastoid process
0.657 0.343 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.655 0.345 0.000
S50-S59 Injuries to the elbow and forearm
0.654 0.346 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.654 0.346 0.000
I50 Heart failure
0.651 0.349 0.000
Chapter I Certain infectious and parasitic diseases
0.638 0.362 0.000
I05 Rheumatic mitral valve diseases
0.636 0.364 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.635 0.365 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.634 0.366 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.633 0.367 0.000
O85-O92 Complications predominantly related to the puerperium
0.625 0.375 0.000
I72 Other aneurysm
0.624 0.376 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.623 0.377 0.000
I47.2 Ventricular tachycardia
0.618 0.382 0.000
Y95 Nosocomial condition
0.618 0.382 0.000
I36 Nonrheumatic tricuspid valve disorders
0.613 0.387 0.000
S69 Other and unspecified injuries of wrist and hand
0.607 0.393 0.000
I25 Chronic ischaemic heart disease
0.605 0.395 0.000
I44.1 Atrioventricular block, second degree
0.603 0.397 0.000
I31.9 Disease of pericardium, unspecified
0.600 0.400 0.000
I35.9 Aortic valve disorder, unspecified
0.600 0.400 0.000
I45 Other conduction disorders
0.600 0.400 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.594 0.406 0.000
I30 Acute pericarditis
0.594 0.406 0.000
O04.1 Incomplete, complicated by delayed or excessive haemorrhage
0.592 0.408 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.591 0.409 0.000
I25.2 Old myocardial infarction
0.591 0.409 0.000
Chapter XXII Codes for special purposes
0.590 0.410 0.000
I33 Acute and subacute endocarditis
0.589 0.411 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.586 0.414 0.000
I70 Atherosclerosis
0.586 0.414 0.000
I73 Other peripheral vascular diseases
0.586 0.414 0.000
A30-A49 Other bacterial diseases
0.584 0.416 0.000
L90 Atrophic disorders of skin
0.582 0.418 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.582 0.418 0.000
I52 Other heart disorders in diseases classified elsewhere
0.582 0.418 0.000
I48 Atrial fibrillation and flutter
0.582 0.418 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.582 0.418 0.000
I41 Myocarditis in diseases classified elsewhere
0.582 0.418 0.000
I40 Acute myocarditis
0.582 0.418 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.582 0.418 0.000
I37 Pulmonary valve disorders
0.582 0.418 0.000
I32 Pericarditis in diseases classified elsewhere
0.582 0.418 0.000
I46 Cardiac arrest
0.582 0.418 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.581 0.419 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.581 0.419 0.000
I42.0 Dilated cardiomyopathy
0.580 0.420 0.000
W20-W49 Exposure to inanimate mechanical forces
0.578 0.422 0.000
O41 Other disorders of amniotic fluid and membranes
0.577 0.423 0.000
I00-I02 Acute rheumatic fever
0.577 0.423 0.000
I71.0 Dissection of aorta [any part]
0.572 0.427 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.568 0.432 0.000
S69.9 Unspecified injury of wrist and hand
0.568 0.432 0.000
O40 Polyhydramnios
0.567 0.433 0.000
O47 False labour
0.567 0.433 0.000
H90-H95 Other disorders of ear
0.566 0.434 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.565 0.435 0.000
I35.8 Other aortic valve disorders
0.564 0.436 0.000
Chapter V Mental and behavioural disorders
0.563 0.437 0.000
S52 Fracture of forearm
0.563 0.437 0.000
S10-S19 Injuries to the neck
0.561 0.438 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.560 0.439 0.000
O00 Ectopic pregnancy
0.559 0.440 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.559 0.441 0.000
T93 Sequelae of injuries of lower limb
0.559 0.441 0.000
I67 Other cerebrovascular diseases
0.558 0.442 0.000
L82 Seborrhoeic keratosis
0.558 0.442 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.558 0.442 0.000
L90.0 Lichen sclerosus et atrophicus
0.557 0.443 0.000
T66-T78 Other and unspecified effects of external causes
0.555 0.445 0.000
I38 Endocarditis, valve unspecified
0.554 0.446 0.000
I74 Arterial embolism and thrombosis
0.552 0.447 0.000
I07 Rheumatic tricuspid valve diseases
0.551 0.449 0.000
O36 Maternal care for other known or suspected foetal problems
0.549 0.451 0.000
T79-T79 Certain early complications of trauma
0.548 0.452 0.000
A41 Other septicaemia
0.547 0.453 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.545 0.455 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.544 0.456 0.000
S90-S99 Injuries to the ankle and foot
0.544 0.456 0.000
I09 Other rheumatic heart diseases
0.542 0.457 0.000
I06 Rheumatic aortic valve diseases
0.542 0.457 0.000
O48 Prolonged pregnancy
0.542 0.458 0.000
I35.1 Aortic (valve) insufficiency
0.541 0.458 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.540 0.460 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.537 0.463 0.000
I21 Acute myocardial infarction
0.537 0.463 0.000
L50-L54 Urticaria and erythema
0.535 0.465 0.000
I51.8 Other ill-defined heart diseases
0.533 0.467 0.000
I50.1 Left ventricular failure
0.532 0.468 0.000
I05.2 Mitral stenosis with insufficiency
0.531 0.468 0.000
I31.3 Pericardial effusion (noninflammatory)
0.531 0.468 0.000
A41.9 Septicaemia, unspecified
0.532 0.468 0.000
S40-S49 Injuries to the shoulder and upper arm
0.529 0.471 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.529 0.471 0.000
W00-W19 Falls
0.528 0.472 0.000
S60 Superficial injury of wrist and hand
0.528 0.472 0.000
D80-D89 Certain disorders involving the immune mechanism
0.528 0.472 0.000
I60 Subarachnoid haemorrhage
0.526 0.473 0.000
O42 Premature rupture of membranes
0.523 0.477 0.000
T33-T35 Frostbite
0.523 0.477 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.523 0.477 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.523 0.477 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.523 0.477 0.000
T00-T07 Injuries involving multiple body regions
0.523 0.477 0.000
I44.6 Other and unspecified fascicular block
0.523 0.477 0.000
I44.5 Left posterior fascicular block
0.523 0.477 0.000
I44.4 Left anterior fascicular block
0.523 0.477 0.000
I44.3 Other and unspecified atrioventricular block
0.523 0.477 0.000
I24 Other acute ischaemic heart diseases
0.522 0.478 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.521 0.479 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.521 0.479 0.000
L40-L45 Papulosquamous disorders
0.520 0.480 0.000
A00-A09 Intestinal infectious diseases
0.519 0.481 0.000
S50 Superficial injury of forearm
0.519 0.481 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.518 0.482 0.000
T92 Sequelae of injuries of upper limb
0.518 0.482 0.000
O08 Complications following abortion and ectopic and molar pregnancy
0.517 0.483 0.000
O07 Failed attempted abortion
0.517 0.483 0.000
O06 Unspecified abortion
0.517 0.483 0.000
O05 Other abortion
0.517 0.483 0.000
O01 Hydatidiform mole
0.517 0.483 0.000
O45 Premature separation of placenta [abruptio placentae]
0.514 0.485 0.000
O44 Placenta praevia
0.514 0.485 0.000
O43 Placental disorders
0.514 0.485 0.000
O33 Maternal care for known or suspected disproportion
0.514 0.485 0.000
O31 Complications specific to multiple gestation
0.514 0.485 0.000
O90 Complications of the puerperium, not elsewhere classified
0.514 0.486 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.514 0.486 0.000
T91 Sequelae of injuries of neck and trunk
0.514 0.486 0.000
I44.0 Atrioventricular block, first degree
0.513 0.487 0.000
H80-H83 Diseases of inner ear
0.513 0.487 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.513 0.487 0.000
S80-S89 Injuries to the knee and lower leg
0.512 0.488 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.512 0.488 0.000
Y35-Y36 Legal intervention and operations of war
0.512 0.488 0.000
Y10-Y34 Event of undetermined intent
0.512 0.488 0.000
Y00-Y09 Assault
0.512 0.488 0.000
X85-X99 Assault
0.512 0.488 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.512 0.488 0.000
X50-X57 Overexertion, travel and privation
0.512 0.488 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.512 0.488 0.000
X30-X39 Exposure to forces of nature
0.512 0.488 0.000
X20-X29 Contact with venomous animals and plants
0.512 0.488 0.000
X10-X19 Contact with heat and hot substances
0.512 0.488 0.000
X00-X09 Exposure to smoke, fire and flames
0.512 0.488 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.512 0.488 0.000
W75-W84 Other accidental threats to breathing
0.512 0.488 0.000
W65-W74 Accidental drowning and submersion
0.512 0.488 0.000
W50-W64 Exposure to animate mechanical forces
0.512 0.488 0.000
V98-V99 Other and unspecified transport accidents
0.512 0.488 0.000
V95-V97 Air and space transport accidents
0.512 0.488 0.000
V90-V94 Water transport accidents
0.512 0.488 0.000
V80-V89 Other land transport accidents
0.512 0.488 0.000
V70-V79 Bus occupant injured in transport accident
0.512 0.488 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.512 0.488 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.512 0.488 0.000
V40-V49 Car occupant injured in transport accident
0.512 0.488 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.512 0.488 0.000
V20-V29 Motorcycle rider injured in transport accident
0.512 0.488 0.000
V01-V09 Pedestrian injured in transport accident
0.512 0.488 0.000
I49 Other cardiac arrhythmias
0.511 0.489 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.510 0.490 0.000
S62 Fracture at wrist and hand level
0.510 0.490 0.000
O04.8 Complete or unspecified, with other and unspecified complications
0.509 0.490 0.000
O04.7 Complete or unspecified, complicated by embolism
0.509 0.490 0.000
O04.6 Complete or unspecified, complicated by delayed or excessive haemorrhage
0.509 0.490 0.000
O04.5 Complete or unspecified, complicated by genital tract and pelvic infection
0.509 0.490 0.000
O04.4 Incomplete, without complication
0.509 0.490 0.000
O04.3 Incomplete, with other and unspecified complications
0.509 0.490 0.000
O04.2 Incomplete, complicated by embolism
0.509 0.490 0.000
O04.0 Incomplete, complicated by genital tract and pelvic infection
0.509 0.490 0.000
Y86 Sequelae of other accidents
0.510 0.490 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.509 0.491 0.000
H65-H75 Diseases of middle ear and mastoid
0.509 0.491 0.000
I51.6 Cardiovascular disease, unspecified
0.509 0.491 0.000
I51.5 Myocardial degeneration
0.509 0.491 0.000
I51.4 Myocarditis, unspecified
0.509 0.491 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.509 0.491 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.509 0.491 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.509 0.491 0.000
I51.0 Cardiac septal defect, acquired
0.509 0.491 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.508 0.492 0.000
S51 Open wound of forearm
0.507 0.492 0.000
I69 Sequelae of cerebrovascular disease
0.506 0.494 0.000
X60-X84 Intentional self-harm
0.505 0.495 0.000
V10-V19 Pedal cyclist injured in transport accident
0.505 0.495 0.000
O30 Multiple gestation
0.504 0.496 0.000
L20-L30 Dermatitis and eczema
0.504 0.496 0.000
I78 Diseases of capillaries
0.503 0.496 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.500 0.499 0.000
I47.0 Reentry ventricular arrhythmia
0.500 0.499 0.000
I31.8 Other specified diseases of pericardium
0.500 0.500 0.000
I31.2 Haemopericardium, not elsewhere classified
0.500 0.500 0.000
I31.1 Chronic constrictive pericarditis
0.500 0.500 0.000
I31.0 Chronic adhesive pericarditis
0.500 0.500 0.000
I22 Subsequent myocardial infarction
0.500 0.500 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.499 0.501 0.000
T18 Foreign body in alimentary tract
0.498 0.502 0.000
H90 Conductive and sensorineural hearing loss
0.498 0.502 0.000
L85 Other epidermal thickening
0.497 0.503 0.000
I08.9 Multiple valve disease, unspecified
0.497 0.503 0.000
I08.8 Other multiple valve diseases
0.497 0.503 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.497 0.503 0.000
I50.0 Congestive heart failure
0.497 0.503 0.000
I72.3 Aneurysm of iliac artery
0.496 0.504 0.000
I47.1 Supraventricular tachycardia
0.496 0.504 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.495 0.505 0.000
B15-B19 Viral hepatitis
0.495 0.505 0.000
Chapter X Diseases of the respiratory system
0.494 0.506 0.000
D60-D64 Aplastic and other anaemias
0.493 0.507 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.491 0.509 0.000
S20-S29 Injuries to the thorax
0.490 0.510 0.000
L93 Lupus erythematosus
0.490 0.510 0.000
Q60-Q64 Congenital malformations of the urinary system
0.489 0.511 0.000
T93.2 Sequelae of other fractures of lower limb
0.489 0.511 0.000
I67.1 Cerebral aneurysm, nonruptured
0.489 0.511 0.000
Y57 Other and unspecified drugs and medicaments
0.488 0.512 0.000
I05.9 Mitral valve disease, unspecified
0.488 0.512 0.000
A80-A89 Viral infections of the central nervous system
0.487 0.513 0.000
O86 Other puerperal infections
0.487 0.513 0.000
I72.8 Aneurysm of other specified arteries
0.486 0.514 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.486 0.514 0.000
I23 Certain current complications following acute myocardial infarction
0.485 0.515 0.000
L10-L14 Bullous disorders
0.485 0.515 0.000
I63 Cerebral infarction
0.484 0.515 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.482 0.518 0.000
I61 Intracerebral haemorrhage
0.482 0.518 0.000
I42.8 Other cardiomyopathies
0.482 0.518 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.482 0.518 0.000
I42.6 Alcoholic cardiomyopathy
0.482 0.518 0.000
I42.5 Other restrictive cardiomyopathy
0.482 0.518 0.000
I42.4 Endocardial fibroelastosis
0.482 0.518 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.482 0.518 0.000
I42.2 Other hypertrophic cardiomyopathy
0.482 0.518 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.482 0.518 0.000
I77 Other disorders of arteries and arterioles
0.481 0.519 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.480 0.519 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.480 0.519 0.000
S68 Traumatic amputation of wrist and hand
0.479 0.521 0.000
S70-S79 Injuries to the hip and thigh
0.479 0.521 0.000
S52.5 Fracture of lower end of radius
0.478 0.522 0.000
A04 Other bacterial intestinal infections
0.477 0.523 0.000
H93 Other disorders of ear, not elsewhere classified
0.477 0.523 0.000
O03 Spontaneous abortion
0.476 0.524 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.476 0.524 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.476 0.524 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.476 0.524 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.476 0.524 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.476 0.524 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.476 0.524 0.000
O41.8 Other specified disorders of amniotic fluid and membranes
0.476 0.524 0.000
T31 Burns classified according to extent of body surface involved
0.476 0.524 0.000
S67 Crushing injury of wrist and hand
0.474 0.525 0.000
S65 Injury of blood vessels at wrist and hand level
0.474 0.525 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.474 0.525 0.000
Y52 Agents primarily affecting the cardiovascular system
0.474 0.525 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.474 0.526 0.000
O47.0 False labour before 37 completed weeks of gestation
0.474 0.526 0.000
D69 Purpura and other haemorrhagic conditions
0.473 0.527 0.000
L84 Corns and callosities
0.473 0.527 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.472 0.528 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.472 0.528 0.000
Y98 Lifestyle-related condition
0.472 0.528 0.000
Y97 Environmental-pollution-related condition
0.472 0.528 0.000
Y96 Work-related condition
0.472 0.528 0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.470 0.530 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.470 0.530 0.000
D55-D59 Haemolytic anaemias
0.470 0.530 0.000
S59 Other and unspecified injuries of forearm
0.469 0.531 0.000
S58 Traumatic amputation of forearm
0.469 0.531 0.000
S57 Crushing injury of forearm
0.469 0.531 0.000
S56 Injury of muscle and tendon at forearm level
0.469 0.531 0.000
S55 Injury of blood vessels at forearm level
0.469 0.531 0.000
S54 Injury of nerves at forearm level
0.469 0.531 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.469 0.531 0.000
T98 Sequelae of other and unspecified effects of external causes
0.469 0.531 0.000
T95 Sequelae of burns, corrosions and frostbite
0.469 0.531 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.469 0.531 0.000
T90 Sequelae of injuries of head
0.469 0.531 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.469 0.531 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.469 0.531 0.000
W22 Striking against or struck by other objects
0.469 0.531 0.000
S61 Open wound of wrist and hand
0.468 0.532 0.000
I25.3 Aneurysm of heart
0.468 0.532 0.000
I42.9 Cardiomyopathy, unspecified
0.467 0.533 0.000
I72.4 Aneurysm of artery of lower extremity
0.466 0.534 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.463 0.537 0.000
O47.9 False labour, unspecified
0.463 0.537 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.462 0.538 0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus
0.462 0.538 0.000
S36 Injury of intra-abdominal organs
0.460 0.540 0.000
I73.0 Raynaud's syndrome
0.459 0.541 0.000
Y43 Primarily systemic agents
0.459 0.541 0.000
O32.8 Maternal care for other malpresentation of foetus
0.458 0.542 0.000
S52.1 Fracture of upper end of radius
0.458 0.542 0.000
B99-B99 Other infectious diseases
0.458 0.542 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.458 0.542 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.458 0.542 0.000
B65-B83 Helminthiases
0.458 0.542 0.000
B50-B64 Protozoal diseases
0.458 0.542 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.458 0.542 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.458 0.542 0.000
A75-A79 Rickettsioses
0.458 0.542 0.000
A70-A74 Other diseases caused by chlamydiae
0.458 0.542 0.000
A65-A69 Other spirochaetal diseases
0.458 0.542 0.000
A20-A28 Certain zoonotic bacterial diseases
0.458 0.542 0.000
A15-A19 Tuberculosis
0.458 0.542 0.000
I45.5 Other specified heart block
0.457 0.542 0.000
I05.8 Other mitral valve diseases
0.456 0.544 0.000
I05.1 Rheumatic mitral insufficiency
0.456 0.544 0.000
I05.0 Mitral stenosis
0.456 0.544 0.000
O32.0 Maternal care for unstable lie
0.456 0.544 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.455 0.545 0.000
Q80-Q89 Other congenital malformations
0.455 0.545 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.455 0.545 0.000
Q50-Q56 Congenital malformations of genital organs
0.455 0.545 0.000
Q35-Q37 Cleft lip and cleft palate
0.455 0.545 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.455 0.545 0.000
Q00-Q07 Congenital malformations of the nervous system
0.455 0.545 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.454 0.546 0.000
L94 Other localised connective tissue disorders
0.454 0.546 0.000
L87 Transepidermal elimination disorders
0.454 0.546 0.000
L88 Pyoderma gangrenosum
0.454 0.546 0.000
L86 Keratoderma in diseases classified elsewhere
0.454 0.546 0.000
L83 Acanthosis nigricans
0.454 0.546 0.000
L80 Vitiligo
0.454 0.546 0.000
W29 Contact with other powered hand tools and household machinery
0.454 0.546 0.000
L95.9 Vasculitis limited to skin, unspecified
0.454 0.546 0.000
O36.9 Maternal care for foetal problem, unspecified
0.453 0.547 0.000
D68 Other coagulation defects
0.452 0.548 0.000
Y45.0 Opioids and related analgesics
0.448 0.552 0.000
O92 Other disorders of breast and lactation associated with childbirth
0.448 0.552 0.000
O91 Infections of breast associated with childbirth
0.448 0.552 0.000
O89 Complications of anaesthesia during the puerperium
0.448 0.552 0.000
O88 Obstetric embolism
0.448 0.552 0.000
O87 Venous complications in the puerperium
0.448 0.552 0.000
O85 Puerperal sepsis
0.448 0.552 0.000
I72.9 Aneurysm of unspecified site
0.448 0.552 0.000
I72.6 Aneurysm and dissection of vertebral artery
0.448 0.552 0.000
I72.5 Aneurysm and dissection of other precerebral arteries
0.448 0.552 0.000
I72.2 Aneurysm of renal artery
0.448 0.552 0.000
I72.1 Aneurysm of artery of upper extremity
0.448 0.552 0.000
I72.0 Aneurysm of carotid artery
0.448 0.552 0.000
Y59 Other and unspecified vaccines and biological substances
0.447 0.553 0.000
Y58 Bacterial vaccines
0.447 0.553 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.447 0.553 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.447 0.553 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.447 0.553 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.447 0.553 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.447 0.553 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.447 0.553 0.000
Y48 Anaesthetics and therapeutic gases
0.447 0.553 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.447 0.553 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.447 0.553 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.447 0.553 0.000
O80-O84 Delivery
0.446 0.554 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.446 0.554 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.445 0.554 0.000
L50 Urticaria
0.445 0.555 0.000
I49.3 Ventricular premature depolarisation
0.445 0.555 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.444 0.556 0.000
O00.1 Tubal pregnancy
0.444 0.556 0.000
Chapter VI Diseases of the nervous system
0.442 0.558 0.000
S12 Fracture of neck
0.441 0.558 0.000
Y40 Systemic antibiotics
0.442 0.558 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.441 0.559 0.000
I34 Nonrheumatic mitral valve disorders
0.441 0.559 0.000
I50.9 Heart failure, unspecified
0.441 0.559 0.000
D50-D53 Nutritional anaemias
0.440 0.560 0.000
I21.4 Acute subendocardial myocardial infarction
0.440 0.560 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.440 0.560 0.000
L81 Other disorders of pigmentation
0.439 0.561 0.000
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.439 0.561 0.000
I36.8 Other nonrheumatic tricuspid valve disorders
0.439 0.561 0.000
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.439 0.561 0.000
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.439 0.561 0.000
D61 Other aplastic anaemias
0.439 0.561 0.000
S64 Injury of nerves at wrist and hand level
0.439 0.561 0.000
I44.7 Left bundle-branch block, unspecified
0.439 0.561 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.439 0.561 0.000
I30.9 Acute pericarditis, unspecified
0.438 0.562 0.000
J30-J39 Other diseases of upper respiratory tract
0.437 0.563 0.000
I45.9 Conduction disorder, unspecified
0.437 0.563 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.436 0.564 0.000
S69.8 Other specified injuries of wrist and hand
0.435 0.565 0.000
S69.7 Multiple injuries of wrist and hand
0.435 0.565 0.000
O90.8 Other complications of the puerperium, not elsewhere classified
0.435 0.565 0.000
I25.6 Silent myocardial ischaemia
0.434 0.566 0.000
I25.4 Coronary artery aneurysm
0.434 0.566 0.000
I73.9 Peripheral vascular disease, unspecified
0.433 0.567 0.000
T68 Hypothermia
0.432 0.568 0.000
J09-J18 Influenza and pneumonia
0.432 0.568 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.432 0.568 0.000
T18.5 Foreign body in anus and rectum
0.431 0.569 0.000
F80-F89 Disorders of psychological development
0.431 0.569 0.000
I45.8 Other specified conduction disorders
0.430 0.570 0.000
I45.6 Preexcitation syndrome
0.430 0.570 0.000
I45.4 Nonspecific intraventricular block
0.430 0.570 0.000
I45.3 Trifascicular block
0.430 0.570 0.000
I45.2 Bifascicular block
0.430 0.570 0.000
I45.0 Right fascicular block
0.430 0.570 0.000
I33.0 Acute and subacute infective endocarditis
0.429 0.570 0.000
L89 Decubitus ulcer
0.429 0.571 0.000
H60-H62 Diseases of external ear
0.429 0.571 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.428 0.572 0.000
L92.0 Granuloma annulare
0.427 0.573 0.000
S50.8 Other superficial injuries of forearm
0.426 0.574 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.426 0.574 0.000
T19 Foreign body in genito-urinary tract
0.426 0.574 0.000
T17 Foreign body in respiratory tract
0.426 0.574 0.000
T15 Foreign body on external eye
0.426 0.574 0.000
T16 Foreign body in ear
0.426 0.574 0.000
I30.8 Other forms of acute pericarditis
0.426 0.574 0.000
I30.1 Infective pericarditis
0.426 0.574 0.000
I30.0 Acute nonspecific idiopathic pericarditis
0.426 0.574 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.426 0.574 0.000
S61.8 Open wound of other parts of wrist and hand
0.425 0.575 0.000
Y88 Sequelae of surgical and medical care as external cause
0.424 0.576 0.000
H90.2 Conductive hearing loss, unspecified
0.424 0.576 0.000
S62.3 Fracture of other metacarpal bone
0.424 0.576 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.424 0.576 0.000
I25.5 Ischaemic cardiomyopathy
0.424 0.576 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.423 0.577 0.000
I62 Other nontraumatic intracranial haemorrhage
0.422 0.577 0.000
I33.9 Acute endocarditis, unspecified
0.422 0.577 0.000
I74.5 Embolism and thrombosis of iliac artery
0.422 0.578 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.421 0.579 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.421 0.579 0.000
O46.9 Antepartum haemorrhage, unspecified
0.421 0.579 0.000
H81 Disorders of vestibular function
0.421 0.579 0.000
A04.8 Other specified bacterial intestinal infections
0.421 0.579 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.420 0.579 0.000
Y89 Sequelae of other external causes
0.420 0.579 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.420 0.579 0.000
I70.9 Generalised and unspecified atherosclerosis
0.420 0.579 0.000
I70.8 Atherosclerosis of other arteries
0.420 0.579 0.000
I70.1 Atherosclerosis of renal artery
0.420 0.579 0.000
I70.0 Atherosclerosis of aorta
0.420 0.579 0.000
O34.1 Maternal care for tumour of corpus uteri
0.420 0.580 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.420 0.580 0.000
I73.8 Other specified peripheral vascular diseases
0.420 0.580 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.420 0.580 0.000
I99 Other and unspecified disorders of circulatory system
0.420 0.580 0.000
F41 Other anxiety disorders
0.419 0.581 0.000
S60.8 Other superficial injuries of wrist and hand
0.419 0.581 0.000
A48 Other bacterial diseases, not elsewhere classified
0.419 0.581 0.000
A44 Bartonellosis
0.419 0.581 0.000
A43 Nocardiosis
0.419 0.581 0.000
A42 Actinomycosis
0.419 0.581 0.000
A40 Streptococcal septicaemia
0.419 0.581 0.000
A39 Meningococcal infection
0.419 0.581 0.000
A37 Whooping cough
0.419 0.581 0.000
A36 Diphtheria
0.419 0.581 0.000
A32 Listeriosis
0.419 0.581 0.000
A31 Infection due to other mycobacteria
0.419 0.581 0.000
A30 Leprosy [Hansen's disease]
0.419 0.581 0.000
A46 Erysipelas
0.419 0.581 0.000
A38 Scarlet fever
0.419 0.581 0.000
A35 Other tetanus
0.419 0.581 0.000
A34 Obstetrical tetanus
0.419 0.581 0.000
A33 Tetanus neonatorum
0.419 0.581 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.419 0.581 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.418 0.582 0.000
W06 Fall involving bed
0.418 0.582 0.000
S92 Fracture of foot, except ankle
0.418 0.582 0.000
L90.9 Atrophic disorder of skin, unspecified
0.418 0.582 0.000
L90.8 Other atrophic disorders of skin
0.418 0.582 0.000
L90.6 Striae atrophicae
0.418 0.582 0.000
L90.4 Acrodermatitis chronica atrophicans
0.418 0.582 0.000
L90.3 Atrophoderma of Pasini and Pierini
0.418 0.582 0.000
L90.2 Anetoderma of Jadassohn-Pellizzari
0.418 0.582 0.000
L90.1 Anetoderma of Schweninger-Buzzi
0.418 0.582 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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