TreeWAS – Variant ID: rs117035790

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	1.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
R50-R69 General symptoms and signs	0.999	0.001
Chapter XIV Diseases of the genitourinary system	0.999	0.001
N30-N39 Other diseases of urinary system	0.999	0.001
Chapter II Neoplasms	0.998	0.002
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.998	0.002
R53 Malaise and fatigue	0.998	0.002
M20-M25 Other joint disorders	0.997	0.003
Chapter I Certain infectious and parasitic diseases	0.997	0.003
Chapter V Mental and behavioural disorders	0.995	0.005
B95-B98 Bacterial, viral and other infectious agents	0.989	0.011
Chapter XX External causes of morbidity and mortality	0.987	0.013
C15-C26 Malignant neoplasms of digestive organs	0.986	0.014
Chapter IV Endocrine, nutritional and metabolic diseases	0.985	0.015
N32 Other disorders of bladder	0.983	0.017
Chapter XXI Factors influencing health status and contact with health services	0.982	0.018
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.982	0.018
Z40-Z54 Persons encountering health services for specific procedures and health care	0.981	0.019
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.981	0.019
N25-N29 Other disorders of kidney and ureter	0.979	0.021
C16 Malignant neoplasm of stomach	0.978	0.022
Z51 Other medical care	0.977	0.023
F00-F09 Organic, including symptomatic, mental disorders	0.976	0.024
N31 Neuromuscular dysfunction of bladder, not elsewhere classified	0.973	0.027
Z51.1 Chemotherapy session for neoplasm	0.972	0.028
M05-M14 Inflammatory polyarthropathies	0.971	0.029
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.967	0.033
N28 Other disorders of kidney and ureter, not elsewhere classified	0.967	0.033
Z50 Care involving use of rehabilitation procedures	0.966	0.034
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.960	0.040
E20-E35 Disorders of other endocrine glands	0.955	0.045
N28.1 Cyst of kidney, acquired	0.952	0.048
M25 Other joint disorders, not elsewhere classified	0.949	0.051
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters	0.948	0.052
C79 Secondary malignant neoplasm of other sites	0.947	0.053
F30-F39 Mood [affective] disorders	0.946	0.054
N30 Cystitis	0.946	0.054
C77.2 Intra-abdominal lymph nodes	0.944	0.056
M24 Other specific joint derangements	0.941	0.059
N31.8 Other neuromuscular dysfunction of bladder	0.938	0.062
M06 Other rheumatoid arthritis	0.936	0.064
R51 Headache	0.936	0.064
M23 Internal derangement of knee	0.933	0.067
C16.9 Stomach, unspecified	0.933	0.067
E10-E14 Diabetes mellitus	0.932	0.068
M21 Other acquired deformities of limbs	0.931	0.069
N32.0 Bladder-neck obstruction	0.929	0.071
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.919	0.081
N32.3 Diverticulum of bladder	0.917	0.083
M06.9 Rheumatoid arthritis, unspecified	0.913	0.087
E27 Other disorders of adrenal gland	0.910	0.090
R47-R49 Symptoms and signs involving speech and voice	0.908	0.092
R21 Rash and other nonspecific skin eruption	0.908	0.092
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.908	0.092
R20 Disturbances of skin sensation	0.906	0.094
M86-M90 Other osteopathies	0.901	0.099
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.899	0.101
C77.5 Intrapelvic lymph nodes	0.899	0.101
C80 Malignant neoplasm without specification of site	0.893	0.107
E70-E90 Metabolic disorders	0.892	0.108
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.891	0.109
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.891	0.109
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters	0.890	0.110
R56 Convulsions, not elsewhere classified	0.890	0.110
F31 Bipolar affective disorder	0.888	0.112
Z50.1 Other physical therapy	0.887	0.113
N20-N23 Urolithiasis	0.887	0.113
Z51.8 Other specified medical care	0.884	0.116
E86 Volume depletion	0.882	0.118
F05 Delirium, not induced by alcohol and other psychoactive substances	0.881	0.119
F03 Unspecified dementia	0.880	0.120
M25.5 Pain in joint	0.879	0.121
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters	0.878	0.122
Z43 Attention to artificial openings	0.871	0.129
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.871	0.129
N32.9 Bladder disorder, unspecified	0.869	0.131
Z42 Follow-up care involving plastic surgery	0.868	0.132
R68 Other general symptoms and signs	0.866	0.134
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.866	0.134
M65-M68 Disorders of synovium and tendon	0.865	0.135
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.861	0.139
A00-A09 Intestinal infectious diseases	0.860	0.140
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.859	0.141
R63 Symptoms and signs concerning food and fluid intake	0.856	0.144
F00 Dementia in Alzheimer's disease	0.851	0.149
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems	0.850	0.150
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.850	0.150
C16.3 Pyloric antrum	0.848	0.152
R47 Speech disturbances, not elsewhere classified	0.846	0.154
M21.3 Wrist or foot drop (acquired)	0.846	0.154
Z50.4 Psychotherapy, not elsewhere classified	0.845	0.155
M23.3 Other meniscus derangements	0.843	0.157
N31.9 Neuromuscular dysfunction of bladder, unspecified	0.843	0.157
M05 Seropositive rheumatoid arthritis	0.842	0.158
Z51.4 Preparatory care for treatment, not elsewhere classified	0.840	0.160
W00-W19 Falls	0.838	0.162
M13 Other arthritis	0.838	0.162
R20.2 Paraesthesia of skin	0.835	0.165
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.835	0.165
M25.57 Pain in joint (Ankle and foot)	0.833	0.167
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.833	0.167
C18 Malignant neoplasm of colon	0.833	0.167
N70-N77 Inflammatory diseases of female pelvic organs	0.831	0.169
R61 Hyperhidrosis	0.828	0.172
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.828	0.172
R52 Pain, not elsewhere classified	0.826	0.174
A30-A49 Other bacterial diseases	0.825	0.175
C16.5 Lesser curvature of stomach, unspecified	0.824	0.176
Z50.0 Cardiac rehabilitation	0.824	0.176
M25.7 Osteophyte	0.823	0.177
E10 Insulin-dependent diabetes mellitus	0.823	0.177
E27.1 Primary adrenocortical insufficiency	0.821	0.179
M89 Other disorders of bone	0.821	0.179
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters	0.818	0.182
C16.2 Body of stomach	0.817	0.183
M35 Other systemic involvement of connective tissue	0.817	0.183
R57 Shock, not elsewhere classified	0.815	0.185
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.814	0.186
C78.7 Secondary malignant neoplasm of liver	0.813	0.187
R46 Symptoms and signs involving appearance and behaviour	0.812	0.188
N20 Calculus of kidney and ureter	0.812	0.188
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters	0.812	0.188
R56.8 Other and unspecified convulsions	0.811	0.189
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.810	0.190
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.810	0.190
E34 Other endocrine disorders	0.808	0.192
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.808	0.192
C77.0 Lymph nodes of head, face and neck	0.805	0.195
C79.2 Secondary malignant neoplasm of skin	0.805	0.195
M23.8 Other internal derangements of knee	0.804	0.196
M24.8 Other specific joint derangements, not elsewhere classified	0.803	0.197
M24.4 Recurrent dislocation and subluxation of joint	0.803	0.197
Chapter XXII Codes for special purposes	0.799	0.201
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters	0.796	0.204
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.796	0.204
N30.9 Cystitis, unspecified	0.796	0.204
Y57 Other and unspecified drugs and medicaments	0.795	0.205
R45 Symptoms and signs involving emotional state	0.794	0.206
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.793	0.207
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.793	0.207
Z50.9 Care involving use of rehabilitation procedure, unspecified	0.791	0.209
M60-M63 Disorders of muscles	0.791	0.209
R50 Fever of unknown origin	0.788	0.212
F32 Depressive episode	0.787	0.213
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.787	0.213
R47.8 Other and unspecified speech disturbances	0.787	0.213
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified	0.786	0.214
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.785	0.215
M25.56 Pain in joint (Lower leg)	0.784	0.216
R63.0 Anorexia	0.783	0.217
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.782	0.217
F31.9 Bipolar affective disorder, unspecified	0.782	0.218
M67 Other disorders of synovium and tendon	0.782	0.218
W20-W49 Exposure to inanimate mechanical forces	0.781	0.219
Y95 Nosocomial condition	0.780	0.220
N30.8 Other cystitis	0.780	0.220
N28.8 Other specified disorders of kidney and ureter	0.780	0.220
Y53 Agents primarily affecting the gastro-intestinal system	0.779	0.221
F05.9 Delirium, unspecified	0.778	0.222
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.777	0.223
R68.8 Other specified general symptoms and signs	0.776	0.224
B25-B34 Other viral diseases	0.775	0.225
C18.0 Caecum	0.774	0.226
Z42.0 Follow-up care involving plastic surgery of head and neck	0.773	0.227
F40-F48 Neurotic, stress-related and somatoform disorders	0.771	0.229
E27.2 Addisonian crisis	0.771	0.229
Z45 Adjustment and management of implanted device	0.771	0.229
M25.77 Osteophyte (Ankle and foot)	0.770	0.230
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.770	0.230
M23.30 Other meniscus derangements (Multiple sites)	0.769	0.231
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.768	0.232
Z50.5 Speech therapy	0.765	0.235
N70 Salpingitis and oophoritis	0.765	0.235
S50-S59 Injuries to the elbow and forearm	0.765	0.235
D37-D48 Neoplasms of uncertain or unknown behaviour	0.765	0.235
M21.6 Other acquired deformities of ankle and foot	0.764	0.236
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters	0.762	0.237
R29.6 Tendency to fall, not elsewhere classified	0.761	0.239
M50-M54 Other dorsopathies	0.761	0.239
V20-V29 Motorcycle rider injured in transport accident	0.761	0.239
F00.9 Dementia in Alzheimer's disease, unspecified	0.761	0.239
N30.0 Acute cystitis	0.761	0.239
Y00-Y09 Assault	0.761	0.239
C80.0 Malignant neoplasm, primary site unknown, so stated	0.760	0.240
E14 Unspecified diabetes mellitus	0.759	0.241
C17 Malignant neoplasm of small intestine	0.757	0.243
E13 Other specified diabetes mellitus	0.756	0.244
E88 Other metabolic disorders	0.756	0.244
T66-T78 Other and unspecified effects of external causes	0.755	0.245
Y46 Antiepileptics and anti-Parkinsonism drugs	0.755	0.245
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.754	0.246
N30.3 Trigonitis	0.754	0.246
A04 Other bacterial intestinal infections	0.751	0.249
C80.9 Malignant neoplasm, unspecified	0.751	0.249
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.750	0.250
M05.9 Seropositive rheumatoid arthritis, unspecified	0.749	0.251
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.749	0.251
A08 Viral and other specified intestinal infections	0.748	0.252
R20.8 Other and unspecified disturbances of skin sensation	0.748	0.252
C25 Malignant neoplasm of pancreas	0.747	0.253
V40-V49 Car occupant injured in transport accident	0.746	0.254
B20-B24 Human immunodeficiency virus [HIV] disease	0.746	0.254
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.746	0.254
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.746	0.254
M25.3 Other instability of joint	0.745	0.255
C26 Malignant neoplasm of other and ill-defined digestive organs	0.744	0.256
N28.9 Disorder of kidney and ureter, unspecified	0.742	0.258
Z51.9 Medical care, unspecified	0.741	0.259
C50-C50 Malignant neoplasm of breast	0.741	0.259
M23.6 Other spontaneous disruption of ligament(s) of knee	0.739	0.261
M35.3 Polymyalgia rheumatica	0.738	0.262
C77.4 Inguinal and lower limb lymph nodes	0.737	0.263
R50.0 Fever with chills	0.737	0.263
Y40 Systemic antibiotics	0.736	0.264
C77.3 Axillary and upper limb lymph nodes	0.736	0.264
R52.1 Chronic intractable pain	0.735	0.265
B65-B83 Helminthiases	0.735	0.265
N34 Urethritis and urethral syndrome	0.735	0.265
Z43.5 Attention to cyctostomy	0.734	0.266
Z50.2 Alcohol rehabilitation	0.734	0.266
W50-W64 Exposure to animate mechanical forces	0.733	0.267
C23 Malignant neoplasm of gallbladder	0.733	0.267
Z22 Carrier of infectious disease	0.733	0.267
C16.0 Cardia	0.732	0.268
M24.1 Other articular cartilage disorders	0.732	0.268
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.730	0.270
F30 Manic episode	0.729	0.271
F60-F69 Disorders of adult personality and behaviour	0.727	0.273
F01 Vascular dementia	0.727	0.273
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.726	0.274
M25.6 Stiffness of joint, not elsewhere classified	0.724	0.275
C64-C68 Malignant neoplasms of urinary tract	0.723	0.277
M00-M03 Infectious arthropathies	0.722	0.278
R91 Abnormal findings on diagnostic imaging of lung	0.721	0.279
Y60-Y69 Misadventures to patients during surgical and medical care	0.720	0.280
X40-X49 Accidental poisoning by and exposure to noxious substances	0.720	0.280
M89.9 Disorder of bone, unspecified	0.718	0.282
M34 Systemic sclerosis	0.718	0.282
M06.3 Rheumatoid nodule	0.717	0.283
F05.8 Other delirium	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
R95-R99 Ill-defined and unknown causes of mortality	0.717	0.283
B99-B99 Other infectious diseases	0.717	0.283
R65 Systemic Inflammatory Response Syndrome [SIRS]	0.717	0.283
R62 Lack of expected normal physiological development	0.717	0.283
R64 Cachexia	0.717	0.283
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.716	0.284
N37 Urethral disorders in diseases classified elsewhere	0.716	0.284
N33 Bladder disorders in diseases classified elsewhere	0.716	0.284
E11 Non-insulin-dependent diabetes mellitus	0.716	0.284
M13.9 Arthritis, unspecified	0.716	0.284
C40-C41 Malignant neoplasms of bone and articular cartilage	0.716	0.284
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.716	0.284
C76 Malignant neoplasm of other and ill-defined sites	0.715	0.285
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.715	0.285
M33 Dermatopolymyositis	0.715	0.285
M32 Systemic lupus erythematosus	0.715	0.285
M30 Polyarteritis nodosa and related conditions	0.715	0.285
M24.2 Disorder of ligament	0.715	0.285
B85-B89 Pediculosis, acariasis and other infestations	0.715	0.285
B50-B64 Protozoal diseases	0.715	0.285
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.715	0.285
A75-A79 Rickettsioses	0.715	0.285
A70-A74 Other diseases caused by chlamydiae	0.715	0.285
A65-A69 Other spirochaetal diseases	0.715	0.285
A20-A28 Certain zoonotic bacterial diseases	0.715	0.285
A15-A19 Tuberculosis	0.715	0.285
X50-X57 Overexertion, travel and privation	0.715	0.285
M24.0 Loose body in joint	0.714	0.286
S52 Fracture of forearm	0.714	0.286
M90 Osteopathies in diseases classified elsewhere	0.714	0.286
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.713	0.287
F70-F79 Mental retardation	0.713	0.287
E10.1 With ketoacidosis	0.713	0.287
M25.59 Pain in joint (Site unspecified)	0.713	0.287
N30.1 Interstitial cystitis (chronic)	0.713	0.287
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.712	0.288
Chapter XII Diseases of the skin and subcutaneous tissue	0.712	0.288
M23.4 Loose body in knee	0.712	0.288
F80-F89 Disorders of psychological development	0.710	0.289
A80-A89 Viral infections of the central nervous system	0.710	0.290
Z51.3 Blood transfusion without reported diagnosis	0.710	0.290
Z63 Other problems related to primary support group, including family circumstances	0.709	0.291
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.708	0.292
M22 Disorders of patella	0.708	0.292
Y35-Y36 Legal intervention and operations of war	0.708	0.292
Y10-Y34 Event of undetermined intent	0.708	0.292
X85-X99 Assault	0.708	0.292
X58-X59 Accidental exposure to other and unspecified factors	0.708	0.292
X30-X39 Exposure to forces of nature	0.708	0.292
X20-X29 Contact with venomous animals and plants	0.708	0.292
X10-X19 Contact with heat and hot substances	0.708	0.292
X00-X09 Exposure to smoke, fire and flames	0.708	0.292
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.708	0.292
W75-W84 Other accidental threats to breathing	0.708	0.292
W65-W74 Accidental drowning and submersion	0.708	0.292
V98-V99 Other and unspecified transport accidents	0.708	0.292
V95-V97 Air and space transport accidents	0.708	0.292
V90-V94 Water transport accidents	0.708	0.292
V70-V79 Bus occupant injured in transport accident	0.708	0.292
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.708	0.292
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.708	0.292
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.708	0.292
V01-V09 Pedestrian injured in transport accident	0.708	0.292
M67.8 Other specified disorders of synovium and tendon	0.708	0.292
N36 Other disorders of urethra	0.708	0.292
R46.2 Strange and inexplicable behaviour	0.708	0.292
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.707	0.293
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.707	0.293
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.706	0.294
R61.9 Hyperhidrosis, unspecified	0.706	0.294
E23 Hypofunction and other disorders of pituitary gland	0.705	0.295
N32.4 Rupture of bladder, nontraumatic	0.705	0.295
N32.2 Vesical fistula, not elsewhere classified	0.705	0.295
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters	0.705	0.295
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters	0.704	0.296
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters	0.704	0.296
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters	0.704	0.296
X60-X84 Intentional self-harm	0.703	0.296
Z44 Fitting and adjustment of external prosthetic device	0.703	0.297
E34.9 Endocrine disorder, unspecified	0.703	0.297
C19 Malignant neoplasm of rectosigmoid junction	0.703	0.297
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.703	0.297
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.702	0.298
N29 Other disorders of kidney and ureter in diseases classified elsewhere	0.702	0.298
N27 Small kidney of unknown cause	0.702	0.298
N25 Disorders resulting from impaired renal tubular function	0.702	0.298
A49 Bacterial infection of unspecified site	0.701	0.299
C16.8 Overlapping lesion of stomach	0.701	0.299
C16.6 Greater curvature of stomach, unspecified	0.701	0.299
C16.4 Pylorus	0.701	0.299
C16.1 Fundus of stomach	0.701	0.299
C15 Malignant neoplasm of oesophagus	0.701	0.299
Z51.6 Desensitisation to allergens	0.700	0.300
R58 Haemorrhage, not elsewhere classified	0.700	0.300
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.700	0.300
F02 Dementia in other diseases classified elsewhere	0.700	0.300
F09 Unspecified organic or symptomatic mental disorder	0.700	0.300
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.700	0.300
N35 Urethral stricture	0.700	0.300
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.700	0.300
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.698	0.302
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.698	0.302
N31.1 Reflex neuropathic bladder, not elsewhere classified	0.698	0.302
N31.0 Uninhibited neuropathic bladder, not elsewhere classified	0.698	0.302
E27.4 Other and unspecified adrenocortical insufficiency	0.698	0.302
Z43.6 Attention to other artificial openings of urinary tract	0.697	0.303
M14 Arthropathies in other diseases classified elsewhere	0.696	0.304
M12 Other specific arthropathies	0.696	0.304
M09 Juvenile arthritis in diseases classified elsewhere	0.696	0.304
M08 Juvenile arthritis	0.696	0.304
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.696	0.304
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.695	0.305
N30.2 Other chronic cystitis	0.693	0.306
N28.0 Ischaemia and infarction of kidney	0.693	0.307
M45-M49 Spondylopathies	0.693	0.307
Z60 Problems related to social environment	0.693	0.307
Z50.6 Orthoptic training	0.692	0.308
Z50.3 Drug rehabilitation	0.692	0.308
F99-F99 Unspecified mental disorder	0.692	0.308
Z46 Fitting and adjustment of other devices	0.691	0.309
Y51 Drugs primarily affecting the autonomic nervous system	0.691	0.309
E16 Other disorders of pancreatic internal secretion	0.690	0.309
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.690	0.310
W07 Fall involving chair	0.690	0.310
M89.8 Other specified disorders of bone	0.690	0.310
E27.9 Disorder of adrenal gland, unspecified	0.690	0.310
M66 Spontaneous rupture of synovium and tendon	0.689	0.311
Y59 Other and unspecified vaccines and biological substances	0.689	0.311
Y58 Bacterial vaccines	0.689	0.311
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.689	0.311
Y50 Central nervous system stimulants, not elsewhere classified	0.689	0.311
Y49 Psychotropic drugs, not elsewhere classified	0.689	0.311
Y48 Anaesthetics and therapeutic gases	0.689	0.311
Y47 Sedatives, hypnotics and antianxiety drugs	0.689	0.311
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters	0.689	0.311
Y45.0 Opioids and related analgesics	0.689	0.311
N20.0 Calculus of kidney	0.688	0.312
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.688	0.312
V80-V89 Other land transport accidents	0.687	0.313
Q50-Q56 Congenital malformations of genital organs	0.687	0.313
R41 Other symptoms and signs involving cognitive functions and awareness	0.686	0.314
M80-M85 Disorders of bone density and structure	0.686	0.314
B02 Zoster [herpes zoster]	0.685	0.315
E35 Disorders of endocrine glands in diseases classified elsewhere	0.685	0.315
E32 Diseases of thymus	0.685	0.315
E31 Polyglandular dysfunction	0.685	0.315
E30 Disorders of puberty, not elsewhere classified	0.685	0.315
E26 Hyperaldosteronism	0.685	0.315
E25 Adrenogenital disorders	0.685	0.315
E24 Cushing's syndrome	0.685	0.315
E20 Hypoparathyroidism	0.685	0.315
N72 Inflammatory disease of cervix uteri	0.685	0.315
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.684	0.316
A08.4 Viral intestinal infection, unspecified	0.683	0.317
M25.8 Other specified joint disorders	0.683	0.317
N70.1 Chronic salpingitis and oophoritis	0.683	0.317
R57.2 Septic shock	0.682	0.318
C79.7 Secondary malignant neoplasm of adrenal gland	0.681	0.319
M25.2 Flail joint	0.680	0.319
M25.1 Fistula of joint	0.680	0.319
M25.0 Haemarthrosis	0.680	0.319
N00-N08 Glomerular diseases	0.680	0.320
F32.2 Severe depressive episode without psychotic symptoms	0.679	0.321
F38 Other mood [affective] disorders	0.678	0.321
F34 Persistent mood [affective] disorders	0.678	0.321
F39 Unspecified mood [affective] disorder	0.678	0.321
Z22.3 Carrier of other specified bacterial diseases	0.678	0.321
N30.4 Irradiation cystitis	0.678	0.322
F41 Other anxiety disorders	0.677	0.323
N21 Calculus of lower urinary tract	0.677	0.323
Y45.8 Other analgesics and antipyretics	0.676	0.324
C78.0 Secondary malignant neoplasm of lung	0.676	0.324
N31.2 Flaccid neuropathic bladder, not elsewhere classified	0.675	0.325
M24.9 Joint derangement, unspecified	0.675	0.325
M24.7 Protrusio acetabuli	0.675	0.325
M24.6 Ankylosis of joint	0.675	0.325
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.675	0.325
M24.5 Contracture of joint	0.675	0.325
Z52 Donors of organs and tissues	0.674	0.325
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters	0.674	0.326
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.674	0.326
M91-M94 Chondropathies	0.674	0.326
M87 Osteonecrosis	0.673	0.327
Z51.0 Radiotherapy session	0.672	0.328
Z43.0 Attention to tracheostomy	0.672	0.328
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.672	0.328
M06.8 Other specified rheumatoid arthritis	0.671	0.329
M06.4 Inflammatory polyarthropathy	0.671	0.329
M06.2 Rheumatoid bursitis	0.671	0.329
M06.1 Adult-onset Still's disease	0.671	0.329
E10.5 With peripheral circulatory complications	0.670	0.329
M21.0 Valgus deformity, not elsewhere classified	0.670	0.330
Y45.2 Propionic acid derivatives	0.670	0.330
M23.9 Internal derangement of knee, unspecified	0.669	0.331
M23.1 Discoid meniscus (congenital)	0.669	0.331
M23.0 Cystic meniscus	0.669	0.331
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.669	0.331
E28 Ovarian dysfunction	0.669	0.331
M23.5 Chronic instability of knee	0.669	0.331
E27.8 Other specified disorders of adrenal gland	0.668	0.332
Z42.1 Follow-up care involving plastic surgery of breast	0.668	0.332
E12 Malnutrition-related diabetes mellitus	0.668	0.332
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.668	0.332
A04.7 Enterocolitis due to Clostridium difficile	0.667	0.333
N99-N99 Other disorders of the genitourinary system	0.667	0.333
M21.9 Acquired deformity of limb, unspecified	0.667	0.333
M21.8 Other specified acquired deformities of limbs	0.667	0.333
M21.7 Unequal limb length (acquired)	0.667	0.333
M21.4 Flat foot [pes planus] (acquired)	0.667	0.333
M21.2 Flexion deformity	0.667	0.333
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.667	0.333
A50-A64 Infections with a predominantly sexual mode of transmission	0.667	0.333
R63.8 Other symptoms and signs concerning food and fluid intake	0.666	0.333
R54 Senility	0.666	0.334
N20.2 Calculus of kidney with calculus of ureter	0.665	0.335
E29 Testicular dysfunction	0.665	0.335
N10-N16 Renal tubulo-interstitial diseases	0.665	0.335
C21 Malignant neoplasm of anus and anal canal	0.664	0.336
Z47 Other orthopaedic follow-up care	0.663	0.337
Z45.1 Adjustment and management of infusion pump	0.663	0.337
B15-B19 Viral hepatitis	0.662	0.338
N20.1 Calculus of ureter	0.662	0.338
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.662	0.338
S52.6 Fracture of lower end of both ulna and radius	0.662	0.338
B90-B94 Sequelae of infectious and parasitic diseases	0.660	0.340
R47.0 Dysphasia and aphasia	0.660	0.340
W13 Fall from, out of or through building or structure	0.659	0.341
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.659	0.341
M21.1 Varus deformity, not elsewhere classified	0.658	0.342
R27 Other lack of coordination	0.658	0.342
W18 Other fall on same level	0.658	0.342
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.658	0.342
E85 Amyloidosis	0.657	0.342
Q00-Q07 Congenital malformations of the nervous system	0.657	0.343
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.657	0.343
N39 Other disorders of urinary system	0.657	0.343
Z43.8 Attention to other artificial openings	0.657	0.343
C77.1 Intrathoracic lymph nodes	0.657	0.343
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.656	0.344
E22 Hyperfunction of pituitary gland	0.656	0.344
Y57.5 X-ray contrast media	0.655	0.344
M06.98 Rheumatoid arthritis, unspecified (Other)	0.655	0.345
R46.4 Slowness and poor responsiveness	0.654	0.346
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.654	0.346
M13.96 Arthritis, unspecified (Lower leg)	0.654	0.346
B00 Herpesviral [herpes simplex] infections	0.654	0.346
F29 Unspecified nonorganic psychosis	0.653	0.347
E27.5 Adrenomedullary hyperfunction	0.653	0.347
E27.3 Drug-induced adrenocortical insufficiency	0.653	0.347
E27.0 Other adrenocortical overactivity	0.653	0.347
V10-V19 Pedal cyclist injured in transport accident	0.652	0.348
C79.9 Secondary malignant neoplasm, unspecified site	0.652	0.348
M13.0 Polyarthritis, unspecified	0.652	0.348
T78 Adverse effects, not elsewhere classified	0.652	0.348
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified	0.651	0.349
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.651	0.349
C51-C58 Malignant neoplasms of female genital organs	0.650	0.349

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations