TreeWAS – Variant ID: rs1171617

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I25.2 Old myocardial infarction	0.122	0.878	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.076	0.924	0.000
I21 Acute myocardial infarction	0.061	0.939	0.000
I21.4 Acute subendocardial myocardial infarction	0.061	0.939	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.044	0.956	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.044	0.956	0.000
I20-I25 Ischaemic heart diseases	0.041	0.959	0.000
I24 Other acute ischaemic heart diseases	0.040	0.960	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.039	0.961	0.000
I25 Chronic ischaemic heart disease	0.038	0.962	0.000
I24.8 Other forms of acute ischaemic heart disease	0.037	0.963	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.036	0.964	0.000
I25.3 Aneurysm of heart	0.030	0.970	0.000
I24.1 Dressler's syndrome	0.030	0.970	0.000
I21.9 Acute myocardial infarction, unspecified	0.030	0.970	0.000
I23 Certain current complications following acute myocardial infarction	0.029	0.971	0.000
I25.4 Coronary artery aneurysm	0.026	0.974	0.000
I25.5 Ischaemic cardiomyopathy	0.025	0.975	0.000
I25.6 Silent myocardial ischaemia	0.025	0.975	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.024	0.976	0.000
I22 Subsequent myocardial infarction	0.024	0.976	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.021	0.979	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.021	0.979	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.021	0.979	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.021	0.979	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.021	0.979	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.021	0.979	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.020	0.979	0.000
I23.8 Other current complications following acute myocardial infarction	0.020	0.980	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.019	0.980	0.000
Q21.1 Atrial septal defect	0.000	0.981	0.019
I22.8 Subsequent myocardial infarction of other sites	0.017	0.983	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.017	0.983	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.016	0.984	0.000
M10.99 Gout, unspecified (Site unspecified)	0.016	0.984	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.014	0.985	0.000
M10.9 Gout, unspecified	0.013	0.987	0.000
M10.90 Gout, unspecified (Multiple sites)	0.011	0.988	0.000
M10.97 Gout, unspecified (Ankle and foot)	0.011	0.989	0.000
M10.92 Gout, unspecified (Upper arm)	0.011	0.989	0.000
M10.93 Gout, unspecified (Forearm)	0.010	0.990	0.000
Q21 Congenital malformations of cardiac septa	0.000	0.990	0.010
I22.9 Subsequent myocardial infarction of unspecified site	0.010	0.990	0.000
M10.98 Gout, unspecified (Other)	0.009	0.990	0.000
M10.95 Gout, unspecified (Pelvic region and thigh)	0.009	0.990	0.000
M10.91 Gout, unspecified (Shoulder region)	0.009	0.990	0.000
M54.94 Dorsalgia, unspecified (Thoracic region)	0.000	0.991	0.009
M10.94 Gout, unspecified (Hand)	0.008	0.992	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.000	0.992	0.008
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.000	0.992	0.008
M84.1 Nonunion of fracture [pseudarthrosis]	0.000	0.992	0.008
Q21.8 Other congenital malformations of cardiac septa	0.000	0.992	0.008
Q21.4 Aortopulmonary septal defect	0.000	0.992	0.007
Q21.2 Atrioventricular septal defect	0.000	0.992	0.007
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.000	0.992	0.008
Q61.2 Polycystic kidney, adult type	0.000	0.992	0.008
Q21.3 Tetralogy of Fallot	0.000	0.993	0.007
M10.96 Gout, unspecified (Lower leg)	0.007	0.993	0.000
Q21.9 Congenital malformation of cardiac septum, unspecified	0.000	0.993	0.007
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.000	0.993	0.007
Q61 Cystic kidney disease	0.000	0.993	0.007
Q21.0 Ventricular septal defect	0.000	0.993	0.007
M10 Gout	0.007	0.993	0.000
L29.0 Pruritus ani	0.007	0.993	0.000
Q60-Q64 Congenital malformations of the urinary system	0.000	0.993	0.007
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.000	0.994	0.006
Q61.3 Polycystic kidney, unspecified	0.000	0.994	0.006
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.000	0.994	0.006
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.000	0.994	0.006
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.000	0.994	0.006
Q63 Other congenital malformations of kidney	0.000	0.994	0.006
Q61.4 Renal dysplasia	0.000	0.994	0.006
M10.0 Idiopathic gout	0.005	0.994	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.000	0.994	0.005
C85.1 B-cell lymphoma, unspecified	0.006	0.994	0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.000	0.995	0.005
Q20-Q28 Congenital malformations of the circulatory system	0.000	0.995	0.005
Q64 Other congenital malformations of urinary system	0.000	0.995	0.005
M10.3 Gout due to impairment of renal function	0.005	0.995	0.000
Q61.8 Other cystic kidney diseases	0.000	0.995	0.005
Q61.1 Polycystic kidney, infantile type	0.000	0.995	0.005
F01.9 Vascular dementia, unspecified	0.005	0.995	0.000
M10.4 Other secondary gout	0.005	0.995	0.000
M10.2 Drug-induced gout	0.005	0.995	0.000
M10.1 Lead-induced gout	0.005	0.995	0.000
Q63.1 Lobulated, fused and horseshoe kidney	0.000	0.995	0.005
Q61.9 Cystic kidney disease, unspecified	0.000	0.995	0.005
Q61.5 Medullary cystic kidney	0.000	0.995	0.005
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.005	0.995	0.000
Q60.0 Renal agenesis, unilateral	0.000	0.995	0.005
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.000	0.995	0.005
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.995	0.005
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.000	0.995	0.005
S01.5 Open wound of lip and oral cavity	0.005	0.995	0.000
I20 Angina pectoris	0.005	0.995	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.000	0.995	0.005
I25.8 Other forms of chronic ischaemic heart disease	0.005	0.995	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.005	0.995	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.000	0.995	0.004
M10.09 Idiopathic gout (Site unspecified)	0.004	0.995	0.000
M10.00 Idiopathic gout (Multiple sites)	0.004	0.995	0.000
Q63.9 Congenital malformation of kidney, unspecified	0.000	0.995	0.004
Q63.2 Ectopic kidney	0.000	0.995	0.004
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.000	0.995	0.004
D14.0 Middle ear, nasal cavity and accessory sinuses	0.000	0.995	0.005
M10.07 Idiopathic gout (Ankle and foot)	0.004	0.995	0.000
Q60.3 Renal hypoplasia, unilateral	0.000	0.995	0.004
M10.06 Idiopathic gout (Lower leg)	0.004	0.996	0.000
R50.9 Fever, unspecified	0.004	0.996	0.000
Q87.4 Marfan's syndrome	0.000	0.996	0.004
Q63.3 Hyperplastic and giant kidney	0.000	0.996	0.004
C69.3 Choroid	0.004	0.996	0.000
Q63.8 Other specified congenital malformations of kidney	0.000	0.996	0.004
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.000	0.996	0.004
M10.08 Idiopathic gout (Other)	0.004	0.996	0.000
M10.05 Idiopathic gout (Pelvic region and thigh)	0.004	0.996	0.000
M10.03 Idiopathic gout (Forearm)	0.004	0.996	0.000
M10.01 Idiopathic gout (Shoulder region)	0.004	0.996	0.000
Q60.6 Potter's syndrome	0.000	0.996	0.004
Q60.5 Renal hypoplasia, unspecified	0.000	0.996	0.004
Q60.4 Renal hypoplasia, bilateral	0.000	0.996	0.004
Q60.1 Renal agenesis, bilateral	0.000	0.996	0.004
Q64.4 Malformation of urachus	0.000	0.996	0.004
O16 Unspecified maternal hypertension	0.004	0.996	0.000
M54.9 Dorsalgia, unspecified	0.000	0.996	0.004
Q63.0 Accessory kidney	0.000	0.996	0.004
Q20 Congenital malformations of cardiac chambers and connexions	0.000	0.996	0.004
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.000	0.996	0.004
Q25 Congenital malformations of great arteries	0.000	0.996	0.004
Q64.9 Congenital malformation of urinary system, unspecified	0.000	0.996	0.004
Q64.8 Other specified congenital malformations of urinary system	0.000	0.996	0.004
Q64.6 Congenital diverticulum of bladder	0.000	0.996	0.004
Q64.5 Congenital absence of bladder and urethra	0.000	0.996	0.004
Q64.2 Congenital posterior urethral valves	0.000	0.996	0.004
Q64.1 Exstrophy of urinary bladder	0.000	0.996	0.004
Q64.0 Epispadias	0.000	0.996	0.004
Q26 Congenital malformations of great veins	0.000	0.996	0.004
M10.39 Gout due to impairment of renal function (Site unspecified)	0.004	0.996	0.000
M10.38 Gout due to impairment of renal function (Other)	0.004	0.996	0.000
M10.37 Gout due to impairment of renal function (Ankle and foot)	0.004	0.996	0.000
M10.36 Gout due to impairment of renal function (Lower leg)	0.004	0.996	0.000
M10.35 Gout due to impairment of renal function (Pelvic region and thigh)	0.004	0.996	0.000
M10.34 Gout due to impairment of renal function (Hand)	0.004	0.996	0.000
M10.33 Gout due to impairment of renal function (Forearm)	0.004	0.996	0.000
M10.32 Gout due to impairment of renal function (Upper arm)	0.004	0.996	0.000
M10.31 Gout due to impairment of renal function (Shoulder region)	0.004	0.996	0.000
M10.30 Gout due to impairment of renal function (Multiple sites)	0.004	0.996	0.000
M10.02 Idiopathic gout (Upper arm)	0.004	0.996	0.000
Z71.1 Person with feared complaint in whom no diagnosis is made	0.004	0.996	0.000
M10.19 Lead-induced gout (Site unspecified)	0.004	0.996	0.000
M10.18 Lead-induced gout (Other)	0.004	0.996	0.000
M10.17 Lead-induced gout (Ankle and foot)	0.004	0.996	0.000
M10.16 Lead-induced gout (Lower leg)	0.004	0.996	0.000
M10.15 Lead-induced gout (Pelvic region and thigh)	0.004	0.996	0.000
M10.14 Lead-induced gout (Hand)	0.004	0.996	0.000
M10.13 Lead-induced gout (Forearm)	0.004	0.996	0.000
M10.12 Lead-induced gout (Upper arm)	0.004	0.996	0.000
M10.11 Lead-induced gout (Shoulder region)	0.004	0.996	0.000
M10.10 Lead-induced gout (Multiple sites)	0.004	0.996	0.000
M10.29 Drug-induced gout (Site unspecified)	0.004	0.996	0.000
M10.28 Drug-induced gout (Other)	0.004	0.996	0.000
M10.27 Drug-induced gout (Ankle and foot)	0.004	0.996	0.000
M10.26 Drug-induced gout (Lower leg)	0.004	0.996	0.000
M10.25 Drug-induced gout (Pelvic region and thigh)	0.004	0.996	0.000
M10.24 Drug-induced gout (Hand)	0.004	0.996	0.000
M10.23 Drug-induced gout (Forearm)	0.004	0.996	0.000
M10.22 Drug-induced gout (Upper arm)	0.004	0.996	0.000
M10.21 Drug-induced gout (Shoulder region)	0.004	0.996	0.000
M10.20 Drug-induced gout (Multiple sites)	0.004	0.996	0.000
M10.49 Other secondary gout (Site unspecified)	0.004	0.996	0.000
M10.48 Other secondary gout (Other)	0.004	0.996	0.000
M10.47 Other secondary gout (Ankle and foot)	0.004	0.996	0.000
M10.46 Other secondary gout (Lower leg)	0.004	0.996	0.000
M10.45 Other secondary gout (Pelvic region and thigh)	0.004	0.996	0.000
M10.44 Other secondary gout (Hand)	0.004	0.996	0.000
M10.43 Other secondary gout (Forearm)	0.004	0.996	0.000
M10.42 Other secondary gout (Upper arm)	0.004	0.996	0.000
M10.41 Other secondary gout (Shoulder region)	0.004	0.996	0.000
M10.40 Other secondary gout (Multiple sites)	0.004	0.996	0.000
Q60.2 Renal agenesis, unspecified	0.000	0.996	0.004
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.000	0.996	0.004
Q64.7 Other congenital malformations of bladder and urethra	0.000	0.996	0.004
Q10.0 Congenital ptosis	0.000	0.996	0.004
L21.9 Seborrhoeic dermatitis, unspecified	0.000	0.996	0.004
Q62.1 Atresia and stenosis of ureter	0.000	0.996	0.004
M54.90 Dorsalgia, unspecified (Multiple sites in spine)	0.000	0.996	0.004
Q50-Q56 Congenital malformations of genital organs	0.000	0.996	0.004
T91.3 Sequelae of injury of spinal cord	0.000	0.996	0.004
Q22.1 Congenital pulmonary valve stenosis	0.000	0.996	0.004
Q24 Other congenital malformations of heart	0.000	0.996	0.004
M10.04 Idiopathic gout (Hand)	0.004	0.996	0.000
L81.4 Other melanin hyperpigmentation	0.000	0.996	0.004
Q87.8 Other specified congenital malformation syndromes, not elsewhere classified	0.000	0.996	0.004
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.000	0.996	0.004
I20.1 Angina pectoris with documented spasm	0.004	0.996	0.000
Q22.5 Ebstein's anomaly	0.000	0.996	0.004
Q62.8 Other congenital malformations of ureter	0.000	0.996	0.004
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.000	0.996	0.004
R50 Fever of unknown origin	0.004	0.996	0.000
Q43.0 Meckel's diverticulum	0.000	0.996	0.004
Q80-Q89 Other congenital malformations	0.000	0.996	0.004
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.004	0.996	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.000	0.996	0.004
Q35-Q37 Cleft lip and cleft palate	0.000	0.996	0.004
M54.97 Dorsalgia, unspecified (Lumbosacral region)	0.000	0.996	0.004
C85.0 Lymphosarcoma	0.004	0.996	0.000
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance	0.000	0.996	0.004
Q25.0 Patent ductus arteriosus	0.000	0.996	0.003
Q28 Other congenital malformations of circulatory system	0.000	0.996	0.003
Q62.7 Congenital vesico-uretero-renal reflux	0.000	0.996	0.003
Q62.6 Malposition of ureter	0.000	0.996	0.003
Q62.4 Agenesis of ureter	0.000	0.996	0.003
Q62.0 Congenital hydronephrosis	0.000	0.996	0.003
Q62.2 Congenital megaloureter	0.000	0.996	0.003
M54.92 Dorsalgia, unspecified (Cervical region)	0.000	0.996	0.004
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.000	0.996	0.003
Q22.8 Other congenital malformations of tricuspid valve	0.000	0.996	0.003
Q22.6 Hypoplastic right heart syndrome	0.000	0.996	0.003
Q22.4 Congenital tricuspid stenosis	0.000	0.996	0.003
Q22.3 Other congenital malformations of pulmonary valve	0.000	0.996	0.003
Q22.2 Congenital pulmonary valve insufficiency	0.000	0.996	0.003
Q22.0 Pulmonary valve atresia	0.000	0.996	0.003
Q25.3 Stenosis of aorta	0.000	0.996	0.003
R50.0 Fever with chills	0.004	0.996	0.000
N13.5 Kinking and stricture of ureter without hydronephrosis	0.000	0.996	0.004
Q30-Q34 Congenital malformations of the respiratory system	0.000	0.996	0.003
Q62.3 Other obstructive defects of renal pelvis and ureter	0.000	0.997	0.003
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances	0.000	0.997	0.003
C69 Malignant neoplasm of eye and adnexa	0.003	0.997	0.000
Q17 Other congenital malformations of ear	0.000	0.997	0.003
Q12 Congenital lens malformations	0.000	0.997	0.003
M54.93 Dorsalgia, unspecified (Cervicothoracic region)	0.000	0.997	0.003
Q25.6 Stenosis of pulmonary artery	0.000	0.997	0.003
Q50.4 Embryonic cyst of Fallopian tube	0.000	0.997	0.003
R50.1 Persistent fever	0.003	0.997	0.000
C85.7 Other specified types of non-Hodgkin's lymphoma	0.003	0.997	0.000
Q53 Undescended testicle	0.000	0.997	0.003
Q87.5 Other congenital malformation syndromes with other skeletal changes	0.000	0.997	0.003
Q87.3 Congenital malformation syndromes involving early overgrowth	0.000	0.997	0.003
Q87.2 Congenital malformation syndromes predominantly involving limbs	0.000	0.997	0.003
Q87.1 Congenital malformation syndromes predominantly associated with short stature	0.000	0.997	0.003
N18.2 Chronic kidney disease, stage 2	0.000	0.997	0.003
N13.8 Other obstructive and reflux uropathy	0.000	0.997	0.003
Q43 Other congenital malformations of intestine	0.000	0.997	0.003
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)	0.000	0.997	0.003
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.000	0.997	0.003
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.000	0.997	0.003
Q20.6 Isomerism of atrial appendages	0.000	0.997	0.003
Q20.5 Discordant atrioventricular connexion	0.000	0.997	0.003
Q20.4 Double inlet ventricle	0.000	0.997	0.003
Q20.3 Discordant ventriculoarterial connexion	0.000	0.997	0.003
Q20.2 Double outlet left ventricle	0.000	0.997	0.003
Q20.1 Double outlet right ventricle	0.000	0.997	0.003
Q20.0 Common arterial trunk	0.000	0.997	0.003
Q16 Congenital malformations of ear causing impairment of hearing	0.000	0.997	0.003
Q13 Congenital malformations of anterior segment of eye	0.000	0.997	0.003
Q40 Other congenital malformations of upper alimentary tract	0.000	0.997	0.003
C69.9 Eye, unspecified	0.003	0.997	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.000	0.997	0.003
Q25.8 Other congenital malformations of great arteries	0.000	0.997	0.003
Q25.5 Atresia of pulmonary artery	0.000	0.997	0.003
Q25.2 Atresia of aorta	0.000	0.997	0.003
Q15 Other congenital malformations of eye	0.000	0.997	0.003
Q23 Congenital malformations of aortic and mitral valves	0.000	0.997	0.003
Q26.9 Congenital malformation of great vein, unspecified	0.000	0.997	0.003
Q26.8 Other congenital malformations of great veins	0.000	0.997	0.003
Q26.6 Portal vein-hepatic artery fistula	0.000	0.997	0.003
Q26.5 Anomalous portal venous connexion	0.000	0.997	0.003
Q26.3 Partial anomalous pulmonary venous connexion	0.000	0.997	0.003
Q26.2 Total anomalous pulmonary venous connexion	0.000	0.997	0.003
Q26.1 Persistent left superior vena cava	0.000	0.997	0.003
Q26.0 Congenital stenosis of vena cava	0.000	0.997	0.003
R50.2 Drug-induced fever	0.003	0.997	0.000
Q14 Congenital malformations of posterior segment of eye	0.000	0.997	0.003
Q24.9 Congenital malformation of the heart, unspecified	0.000	0.997	0.003
Q25.7 Other congenital malformations of pulmonary artery	0.000	0.997	0.003
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.000	0.997	0.003
Q28.3 Other malformations of cerebral vessels	0.000	0.997	0.003
E22 Hyperfunction of pituitary gland	0.000	0.997	0.003
C69.0 Conjunctiva	0.003	0.997	0.000
Q50.0 Congenital absence of ovary	0.000	0.997	0.003
Q10.7 Congenital malformation of orbit	0.000	0.997	0.003
Q10.6 Other congenital malformations of lachrymal apparatus	0.000	0.997	0.003
Q10.5 Congenital stenosis and stricture of lachrymal duct	0.000	0.997	0.003
Q10.4 Absence and agenesis of lachrymal apparatus	0.000	0.997	0.003
Q10.3 Other congenital malformations of eyelid	0.000	0.997	0.003
Q10.2 Congenital entropion	0.000	0.997	0.003
Q10.1 Congenital ectropion	0.000	0.997	0.003
Q61.0 Congenital single renal cyst	0.000	0.997	0.003
Q50.5 Embryonic cyst of broad ligament	0.000	0.997	0.003
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.000	0.997	0.003
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)	0.000	0.997	0.003
Q55 Other congenital malformations of male genital organs	0.000	0.997	0.003
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.000	0.997	0.003
Q96 Turner's syndrome	0.000	0.997	0.003
Q24.5 Malformation of coronary vessels	0.000	0.997	0.003
R50.8 Other specified fever	0.003	0.997	0.000
W13.9 Unspecified place	0.000	0.997	0.003
Q56 Indeterminate sex and pseudohermaphroditism	0.000	0.997	0.003
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.000	0.997	0.003
Q54 Hypospadias	0.000	0.997	0.003
Q24.3 Pulmonary infundibular stenosis	0.000	0.997	0.003
Q24.2 Cor triatriatum	0.000	0.997	0.003
Q24.1 Levocardia	0.000	0.997	0.003
Y83.9 Surgical procedure, unspecified	0.000	0.997	0.003
D14 Benign neoplasm of middle ear and respiratory system	0.000	0.997	0.003
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.000	0.997	0.003
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.000	0.997	0.003
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.000	0.997	0.003
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.000	0.997	0.003
Q91 Edwards' syndrome and Patau's syndrome	0.000	0.997	0.003
Q62.5 Duplication of ureter	0.000	0.997	0.003
Q99 Other chromosome abnormalities, not elsewhere classified	0.000	0.997	0.003
Q90 Down's syndrome	0.000	0.997	0.003
Q40.3 Congenital malformation of stomach, unspecified	0.000	0.997	0.003
Q50.6 Other congenital malformatons of Fallopian tube and broad ligament	0.000	0.997	0.003
Q50.3 Other congenital malformations of ovary	0.000	0.997	0.003
Q50.2 Congenital torsion of ovary	0.000	0.997	0.003
Q50.1 Developmental ovarian cyst	0.000	0.997	0.003
Q24.4 Congenital subaortic stenosis	0.000	0.997	0.003
Q53.1 Undescended testicle, unilateral	0.000	0.997	0.003
Q37 Cleft palate with cleft lip	0.000	0.997	0.003
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.000	0.997	0.003
Q84 Other congenital malformations of integument	0.000	0.997	0.003
Q81 Epidermolysis bullosa	0.000	0.997	0.003
Q80 Congenital ichthyosis	0.000	0.997	0.003
Q17.5 Prominent ear	0.000	0.997	0.003
Q36 Cleft lip	0.000	0.997	0.003
Q42 Congenital absence, atresia and stenosis of large intestine	0.000	0.997	0.003
Q41 Congenital absence, atresia and stenosis of small intestine	0.000	0.997	0.003
M54.99 Dorsalgia, unspecified (Site unspecified)	0.000	0.997	0.003
Q35 Cleft palate	0.000	0.997	0.003
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.997	0.003
Q12.0 Congenital cataract	0.000	0.997	0.003
Q24.0 Dextrocardia	0.000	0.997	0.003
Q28.9 Congenital malformation of circulatory system, unspecified	0.000	0.997	0.003
Q28.8 Other specified congenital malformations of circulatory system	0.000	0.997	0.003
Q28.1 Other malformations of precerebral vessels	0.000	0.997	0.003
Q55.6 Other congenital malformations of penis	0.000	0.997	0.003
M54.95 Dorsalgia, unspecified (Thoracolumbar region)	0.000	0.997	0.003
C69.6 Orbit	0.003	0.997	0.000
Q18 Other congenital malformations of face and neck	0.000	0.997	0.003
Q53.9 Undescended testicle, unspecified	0.000	0.997	0.003
Q24.6 Congenital heart block	0.000	0.997	0.003
Q40.1 Congenital hiatus hernia	0.000	0.997	0.003
Q53.2 Undescended testicle, bilateral	0.000	0.997	0.003
Q52 Other congenital malformations of female genitalia	0.000	0.997	0.003
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.000	0.997	0.003
C69.4 Ciliary body	0.003	0.997	0.000
Q27 Other congenital malformations of peripheral vascular system	0.000	0.997	0.003
Q34 Other congenital malformations of respiratory system	0.000	0.997	0.003
Q33 Congenital malformations of lung	0.000	0.997	0.003
Q32 Congenital malformations of trachea and bronchus	0.000	0.997	0.003
D14.1 Larynx	0.000	0.997	0.003
E22.1 Hyperprolactinaemia	0.000	0.997	0.003
C69.8 Overlapping lesion of eye and adnexa	0.003	0.997	0.000
C69.5 Lachrymal gland and duct	0.003	0.997	0.000
C69.1 Cornea	0.003	0.997	0.000
Q17.9 Congenital malformation of ear, unspecified	0.000	0.997	0.003
Q17.8 Other specified congenital malformations of ear	0.000	0.997	0.003
Q17.4 Misplaced ear	0.000	0.997	0.003
Q17.3 Other misshapen ear	0.000	0.997	0.003
Q17.2 Microtia	0.000	0.997	0.003
Q17.1 Macrotia	0.000	0.997	0.003
Q17.0 Accessory auricle	0.000	0.997	0.003
Q25.4 Other congenital malformations of aorta	0.000	0.997	0.002
Z57.2 Occupational exposure to dust	0.003	0.997	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.000	0.997	0.003
Q00-Q07 Congenital malformations of the nervous system	0.000	0.997	0.003
D14.3 Bronchus and lung	0.000	0.997	0.003
Q12.9 Congenital lens malformation, unspecified	0.000	0.997	0.003
Q12.8 Other congenital lens malformations	0.000	0.997	0.003
Q12.4 Spherophakia	0.000	0.997	0.003
Q12.3 Congenital aphakia	0.000	0.997	0.003
Q12.2 Coloboma of lens	0.000	0.997	0.003
Q12.1 Congenital displaced lens	0.000	0.997	0.003
Q30 Congenital malformations of nose	0.000	0.997	0.003
C69.2 Retina	0.003	0.997	0.000
Q53.0 Ectopic testis	0.000	0.997	0.003
Q85 Phakomatoses, not elsewhere classified	0.000	0.997	0.003
H44.2 Degenerative myopia	0.003	0.997	0.000
Q24.8 Other specified congenital malformations of heart	0.000	0.997	0.003
Q40.8 Other specified congenital malformations of upper alimentary tract	0.000	0.997	0.003
Q25.1 Coarctation of aorta	0.000	0.997	0.002
Q28.0 Arteriovenous malformation of precerebral vessels	0.000	0.997	0.002
Q31 Congenital malformations of larynx	0.000	0.997	0.002
Q43.7 Persistent cloaca	0.000	0.997	0.002
Q43.6 Congenital fistula of rectum and anus	0.000	0.997	0.002
Q43.5 Ectopic anus	0.000	0.997	0.002
Q43.4 Duplication of intestine	0.000	0.997	0.002
Q43.2 Other congenital functional disorders of colon	0.000	0.997	0.002
O20.9 Haemorrhage in early pregnancy, unspecified	0.000	0.997	0.003
Q13.9 Congenital malformation of anterior segment of eye, unspecified	0.000	0.997	0.002
Q13.8 Other congenital malformations of anterior segment of eye	0.000	0.997	0.002
Q13.5 Blue sclera	0.000	0.997	0.002
Q13.4 Other congenital corneal malformations	0.000	0.997	0.002
Q13.3 Congenital corneal opacity	0.000	0.997	0.002
Q13.2 Other congenital malformations of iris	0.000	0.997	0.002
Q13.1 Absence of iris	0.000	0.997	0.002
Q13.0 Coloboma of iris	0.000	0.997	0.002
Q16.9 Congenital malformation of ear causing impairment of hearing, unspecified	0.000	0.997	0.002
Q16.5 Congenital malformation of inner ear	0.000	0.997	0.002
Q16.4 Other congenital malformations of middle ear	0.000	0.997	0.002
Q16.3 Congenital malformation of ear ossicles	0.000	0.997	0.002
Q16.2 Absence of eustachian tube	0.000	0.997	0.002
Q16.1 Congenital absence, atresia and stricture of auditory canal (external)	0.000	0.997	0.002
Q16.0 Congenital absence of (ear) auricle	0.000	0.997	0.002
Q44.6 Cystic disease of liver	0.000	0.997	0.003
Q15.9 Congenital malformation of eye, unspecified	0.000	0.997	0.002
Q15.8 Other specified congenital malformations of eye	0.000	0.997	0.002
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.000	0.997	0.002
Q23.8 Other congenital malformations of aortic and mitral valves	0.000	0.997	0.002
Q23.4 Hypoplastic left heart syndrome	0.000	0.997	0.002
Q23.2 Congenital mitral stenosis	0.000	0.997	0.002
Q40.9 Congenital malformation of upper alimentary tract, unspecified	0.000	0.997	0.002
Q40.0 Congenital hypertrophic pyloric stenosis	0.000	0.997	0.002
Q15.0 Congenital glaucoma	0.000	0.997	0.002
Q23.3 Congenital mitral insufficiency	0.000	0.997	0.002
Q54.0 Hypospadias, balanic	0.000	0.997	0.002
G25.8 Other specified extrapyramidal and movement disorders	0.003	0.997	0.000
Q14.9 Congenital malformation of posterior segment of eye, unspecified	0.000	0.997	0.002
Q14.8 Other congenital malformations of posterior segment of eye	0.000	0.997	0.002
Q14.3 Congenital malformation of choroid	0.000	0.997	0.002
Q14.2 Congenital malformation of optic disk	0.000	0.997	0.002
Q14.0 Congenital malformation of vitreous humour	0.000	0.997	0.002
Q23.0 Congenital stenosis of aortic valve	0.000	0.997	0.002
Q38.5 Congenital malformations of palate, not elsewhere classified	0.000	0.997	0.002
Q43.3 Congenital malformations of intestinal fixation	0.000	0.997	0.002
E22.8 Other hyperfunction of pituitary gland	0.000	0.997	0.002
Q43.1 Hirschsprung's disease	0.000	0.997	0.002
Q96.9 Turner's syndrome, unspecified	0.000	0.997	0.002
Q98.4 Klinefelter's syndrome, unspecified	0.000	0.997	0.002
H43.3 Other vitreous opacities	0.003	0.997	0.000
Q14.1 Congenital malformation of retina	0.000	0.997	0.002
Q44.7 Other congenital malformations of liver	0.000	0.997	0.002
Q44.4 Choledochal cyst	0.000	0.997	0.002
Q55.0 Absence and aplasia of testis	0.000	0.997	0.002
Q11.3 Macrophthalmos	0.000	0.997	0.002
Q11.2 Microphthalmos	0.000	0.997	0.002
Q11.0 Cystic eyeball	0.000	0.997	0.002
T84.2 Mechanical complication of internal fixation device of other bones	0.000	0.997	0.003
Q89 Other congenital malformations, not elsewhere classified	0.000	0.997	0.002
Q54.8 Other hypospadias	0.000	0.997	0.002
Q55.9 Congenital malformation of male genital organ, unspecified	0.000	0.997	0.002
Q55.8 Other specified congenital malformations of male genital organs	0.000	0.997	0.002
Q55.5 Congenital absence and aplasia of penis	0.000	0.997	0.002
Q55.3 Atresia of vas deferens	0.000	0.997	0.002
Q55.1 Hypoplasia of testis and scrotum	0.000	0.997	0.002
E22.0 Acromegaly and pituitary gigantism	0.000	0.998	0.002
Q96.8 Other variants of Turner's syndrome	0.000	0.998	0.002
Q96.4 Mosaicism, 45,X/other cell line(s) with abnormal sex chromosome	0.000	0.998	0.002
Q96.3 Mosaicism, 45,X/46,XX or XY	0.000	0.998	0.002
Q96.2 Karyotype 46,X with abnormal sex chromosome, except iso (Xq)	0.000	0.998	0.002
Q96.1 Karyotype 46,X iso (Xq)	0.000	0.998	0.002
Q96.0 Karyotype 45,X	0.000	0.998	0.002
Q98.9 Sex chromosome abnormality, male phenotype, unspecified	0.000	0.998	0.002
Q98.8 Other specified sex chromosome abnormalities, male phenotype	0.000	0.998	0.002
Q98.7 Male with sex chromosome mosaicism	0.000	0.998	0.002
Q98.6 Male with structurally abnormal sex chromosome	0.000	0.998	0.002
Q98.5 Karyotype 47,XYY	0.000	0.998	0.002
Q98.3 Other male with 46,XX karyotype	0.000	0.998	0.002
Q98.2 Klinefelter's syndrome, male with 46,XX karyotype	0.000	0.998	0.002
Q98.1 Klinefelter's syndrome, male with more than two X chromosomes	0.000	0.998	0.002
Q98.0 Klinefelter's syndrome karyotype 47,XXY	0.000	0.998	0.002
Z92.0 Personal history of contraception	0.000	0.998	0.002
Q83 Congenital malformations of breast	0.000	0.998	0.002
Q54.9 Hypospadias, unspecified	0.000	0.998	0.002
Q56.4 Indeterminate sex, unspecified	0.000	0.998	0.002
Q56.3 Pseudohermaphroditism, unspecified	0.000	0.998	0.002
Q56.2 Female pseudohermaphroditism, not elsewhere classified	0.000	0.998	0.002
Q56.1 Male pseudohermaphroditism, not elsewhere classified	0.000	0.998	0.002
Q56.0 Hermaphroditism, not elsewhere classified	0.000	0.998	0.002
I31.9 Disease of pericardium, unspecified	0.002	0.998	0.000
Q44.3 Congenital stenosis and stricture of bile ducts	0.000	0.998	0.002
Q44.2 Atresia of bile ducts	0.000	0.998	0.002
Q44.1 Other congenital malformations of gallbladder	0.000	0.998	0.002
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder	0.000	0.998	0.002
Q54.4 Congenital chordee	0.000	0.998	0.002
Q54.3 Hypospadias, perineal	0.000	0.998	0.002
Q54.2 Hypospadias, penoscrotal	0.000	0.998	0.002
Q91.7 Patau's syndrome, unspecified	0.000	0.998	0.002
Q91.6 Trisomy 13, translocation	0.000	0.998	0.002
Q91.5 Trisomy 13, mosaicism (mitotic nondisjunction)	0.000	0.998	0.002
Q91.4 Trisomy 13, meiotic nondisjunction	0.000	0.998	0.002
Q91.3 Edwards' syndrome, unspecified	0.000	0.998	0.002
Q91.2 Trisomy 18, translocation	0.000	0.998	0.002
Q91.1 Trisomy 18, mosaicism (mitotic nondisjunction)	0.000	0.998	0.002
Q91.0 Trisomy 18, meiotic nondisjunction	0.000	0.998	0.002
Q92.9 Trisomy and partial trisomy of autosomes, unspecified	0.000	0.998	0.002
Q92.8 Other specified trisomies and partial trisomies of autosomes	0.000	0.998	0.002
Q92.7 Triploidy and polyploidy	0.000	0.998	0.002
Q92.6 Extra marker chromosomes	0.000	0.998	0.002
Q92.5 Duplications with other complex rearrangements	0.000	0.998	0.002
Q92.4 Duplications seen only at prometaphase	0.000	0.998	0.002
Q92.3 Minor partial trisomy	0.000	0.998	0.002
Q92.2 Major partial trisomy	0.000	0.998	0.002
Q92.1 Whole chromosome trisomy, mosaicism (mitotic nondisjunction)	0.000	0.998	0.002
Q92.0 Whole chromosome trisomy, meiotic nondisjunction	0.000	0.998	0.002
Q93.9 Deletion from autosomes, unspecified	0.000	0.998	0.002
Q93.8 Other deletions from the autosomes	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations