TreeWAS – Variant ID: rs117509195

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I50.1 Left ventricular failure	0.000	0.640	0.360
I50 Heart failure	0.000	0.654	0.346
I30-I52 Other forms of heart disease	0.000	0.692	0.308
I34 Nonrheumatic mitral valve disorders	0.000	0.700	0.300
I50.0 Congestive heart failure	0.000	0.702	0.298
I50.9 Heart failure, unspecified	0.000	0.708	0.292
I51 Complications and ill-defined descriptions of heart disease	0.000	0.711	0.289
I34.0 Mitral (valve) insufficiency	0.000	0.711	0.289
I51.7 Cardiomegaly	0.000	0.726	0.274
I34.1 Mitral (valve) prolapse	0.000	0.738	0.262
I49 Other cardiac arrhythmias	0.000	0.748	0.252
I46 Cardiac arrest	0.000	0.757	0.243
I42 Cardiomyopathy	0.000	0.759	0.241
I38 Endocarditis, valve unspecified	0.000	0.767	0.233
I49.8 Other specified cardiac arrhythmias	0.000	0.768	0.232
I51.8 Other ill-defined heart diseases	0.000	0.769	0.231
I51.9 Heart disease, unspecified	0.000	0.773	0.227
I52 Other heart disorders in diseases classified elsewhere	0.000	0.779	0.221
I48 Atrial fibrillation and flutter	0.000	0.779	0.221
I43 Cardiomyopathy in diseases classified elsewhere	0.000	0.779	0.221
I41 Myocarditis in diseases classified elsewhere	0.000	0.779	0.221
I40 Acute myocarditis	0.000	0.779	0.221
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.000	0.779	0.221
I37 Pulmonary valve disorders	0.000	0.779	0.221
I32 Pericarditis in diseases classified elsewhere	0.000	0.779	0.221
I35 Nonrheumatic aortic valve disorders	0.000	0.779	0.221
I36 Nonrheumatic tricuspid valve disorders	0.000	0.782	0.218
I34.8 Other nonrheumatic mitral valve disorders	0.000	0.785	0.215
I34.2 Nonrheumatic mitral (valve) stenosis	0.000	0.785	0.215
I33 Acute and subacute endocarditis	0.000	0.790	0.210
I51.5 Myocardial degeneration	0.000	0.792	0.208
I51.4 Myocarditis, unspecified	0.000	0.792	0.208
I51.3 Intracardiac thrombosis, not elsewhere classified	0.000	0.792	0.208
I51.2 Rupture of papillary muscle, not elsewhere classified	0.000	0.792	0.208
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.000	0.792	0.208
I51.0 Cardiac septal defect, acquired	0.000	0.792	0.208
I30 Acute pericarditis	0.000	0.792	0.208
I42.0 Dilated cardiomyopathy	0.000	0.796	0.204
I45 Other conduction disorders	0.000	0.798	0.202
I49.9 Cardiac arrhythmia, unspecified	0.000	0.804	0.196
I49.5 Sick sinus syndrome	0.000	0.806	0.194
I46.9 Cardiac arrest, unspecified	0.000	0.807	0.193
I42.2 Other hypertrophic cardiomyopathy	0.000	0.809	0.191
I31 Other diseases of pericardium	0.000	0.809	0.191
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.000	0.814	0.185
I49.2 Junctional premature depolarisation	0.000	0.819	0.181
I49.1 Atrial premature depolarisation	0.000	0.819	0.181
I46.0 Cardiac arrest with successful resuscitation	0.000	0.820	0.180
I46.1 Sudden cardiac death, so described	0.000	0.825	0.175
I35.2 Aortic (valve) stenosis with insufficiency	0.000	0.826	0.174
I42.7 Cardiomyopathy due to drugs and other external agents	0.000	0.827	0.173
I42.6 Alcoholic cardiomyopathy	0.000	0.827	0.173
I42.5 Other restrictive cardiomyopathy	0.000	0.827	0.173
I42.4 Endocardial fibroelastosis	0.000	0.827	0.173
I42.3 Endomyocardial (eosinophilic) disease	0.000	0.827	0.173
I42.1 Obstructive hypertrophic cardiomyopathy	0.000	0.827	0.173
I35.1 Aortic (valve) insufficiency	0.000	0.834	0.165
I42.8 Other cardiomyopathies	0.000	0.837	0.163
I30.9 Acute pericarditis, unspecified	0.000	0.838	0.162
I35.0 Aortic (valve) stenosis	0.000	0.840	0.160
I51.6 Cardiovascular disease, unspecified	0.000	0.841	0.159
I32.8 Pericarditis in other diseases classified elsewhere	0.000	0.841	0.159
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.841	0.159
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.000	0.841	0.159
I37.9 Pulmonary valve disorder, unspecified	0.000	0.841	0.159
I37.8 Other pulmonary valve disorders	0.000	0.841	0.159
I37.2 Pulmonary valve stenosis with insufficiency	0.000	0.841	0.159
I37.1 Pulmonary valve insufficiency	0.000	0.841	0.159
I37.0 Pulmonary valve stenosis	0.000	0.841	0.159
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.000	0.841	0.159
I39.4 Multiple valve disorders in diseases classified elsewhere	0.000	0.841	0.159
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.000	0.841	0.159
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.000	0.841	0.159
I39.1 Aortic valve disorders in diseases classified elsewhere	0.000	0.841	0.159
I39.0 Mitral valve disorders in diseases classified elsewhere	0.000	0.841	0.159
I40.9 Acute myocarditis, unspecified	0.000	0.841	0.159
I40.8 Other acute myocarditis	0.000	0.841	0.159
I40.1 Isolated myocarditis	0.000	0.841	0.159
I40.0 Infective myocarditis	0.000	0.841	0.159
I41.8 Myocarditis in other diseases classified elsewhere	0.000	0.841	0.159
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.841	0.159
I41.1 Myocarditis in viral diseases classified elsewhere	0.000	0.841	0.159
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.000	0.841	0.159
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.000	0.841	0.159
I43.2 Cardiomyopathy in nutritional diseases	0.000	0.841	0.159
I43.1 Cardiomyopathy in metabolic diseases	0.000	0.841	0.159
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.000	0.841	0.159
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.000	0.841	0.159
I48.4 Atypical atrial flutter	0.000	0.841	0.159
I48.3 Typical atrial flutter	0.000	0.841	0.159
I48.2 Chronic atrial fibrillation	0.000	0.841	0.159
I48.1 Persistent atrial fibrillation	0.000	0.841	0.159
I48.0 Paroxysmal atrial fibrillation	0.000	0.841	0.159
I52.8 Other heart disorders in other diseases classified elsewhere	0.000	0.841	0.159
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.841	0.159
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.000	0.841	0.159
I49.0 Ventricular fibrillation and flutter	0.000	0.842	0.158
I47 Paroxysmal tachycardia	0.000	0.843	0.157
I35.8 Other aortic valve disorders	0.000	0.844	0.156
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.000	0.844	0.156
I36.8 Other nonrheumatic tricuspid valve disorders	0.000	0.844	0.156
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.000	0.844	0.156
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.000	0.844	0.156
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.000	0.847	0.153
I33.9 Acute endocarditis, unspecified	0.000	0.849	0.151
I45.5 Other specified heart block	0.000	0.849	0.151
I49.4 Other and unspecified premature depolarisation	0.000	0.851	0.149
I30.8 Other forms of acute pericarditis	0.000	0.851	0.149
I30.0 Acute nonspecific idiopathic pericarditis	0.000	0.851	0.149
I45.8 Other specified conduction disorders	0.000	0.855	0.145
I45.4 Nonspecific intraventricular block	0.000	0.855	0.145
I45.3 Trifascicular block	0.000	0.855	0.145
I45.2 Bifascicular block	0.000	0.855	0.145
I45.0 Right fascicular block	0.000	0.855	0.145
I45.9 Conduction disorder, unspecified	0.000	0.856	0.144
I45.6 Preexcitation syndrome	0.000	0.858	0.142
I33.0 Acute and subacute infective endocarditis	0.000	0.860	0.140
I42.9 Cardiomyopathy, unspecified	0.000	0.862	0.137
I31.8 Other specified diseases of pericardium	0.000	0.863	0.137
I31.2 Haemopericardium, not elsewhere classified	0.000	0.863	0.137
I31.1 Chronic constrictive pericarditis	0.000	0.863	0.137
I31.0 Chronic adhesive pericarditis	0.000	0.863	0.137
I31.3 Pericardial effusion (noninflammatory)	0.000	0.863	0.137
I49.3 Ventricular premature depolarisation	0.000	0.868	0.131
I35.9 Aortic valve disorder, unspecified	0.000	0.872	0.128
I45.1 Other and unspecified right bundle-branch block	0.000	0.877	0.123
I30.1 Infective pericarditis	0.000	0.884	0.115
I47.9 Paroxysmal tachycardia, unspecified	0.000	0.886	0.114
I47.0 Reentry ventricular arrhythmia	0.000	0.887	0.113
I31.9 Disease of pericardium, unspecified	0.000	0.891	0.109
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.099	0.901	0.000
I47.2 Ventricular tachycardia	0.000	0.901	0.099
T36-T50 Poisoning by drugs, medicaments and biological substances	0.098	0.902	0.000
T85 Complications of other internal prosthetic devices, implants and grafts	0.095	0.905	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.093	0.907	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.092	0.908	0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.092	0.908	0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.092	0.908	0.000
S40-S49 Injuries to the shoulder and upper arm	0.091	0.909	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.089	0.911	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.086	0.914	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.086	0.914	0.000
S42 Fracture of shoulder and upper arm	0.084	0.916	0.000
T43.2 Other and unspecified antidepressants	0.084	0.916	0.000
T90 Sequelae of injuries of head	0.082	0.918	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.081	0.918	0.000
T79-T79 Certain early complications of trauma	0.081	0.919	0.000
S42.2 Fracture of upper end of humerus	0.081	0.919	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.079	0.921	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.079	0.921	0.000
S42.20 Fracture of upper end of humerus (closed)	0.078	0.922	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.078	0.922	0.000
T91 Sequelae of injuries of neck and trunk	0.078	0.922	0.000
T85.4 Mechanical complication of breast prosthesis and implant	0.078	0.922	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.077	0.923	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.076	0.924	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.076	0.924	0.000
S10-S19 Injuries to the neck	0.075	0.924	0.000
T92 Sequelae of injuries of upper limb	0.075	0.925	0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.075	0.925	0.000
T66-T78 Other and unspecified effects of external causes	0.074	0.926	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.074	0.926	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.074	0.926	0.000
I47.1 Supraventricular tachycardia	0.000	0.927	0.073
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.073	0.927	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.073	0.927	0.000
T33-T35 Frostbite	0.071	0.928	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.071	0.928	0.000
T00-T07 Injuries involving multiple body regions	0.071	0.928	0.000
T63 Toxic effect of contact with venomous animals	0.071	0.929	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.071	0.929	0.000
T90.4 Sequelae of injury of eye and orbit	0.070	0.929	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.070	0.930	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.070	0.930	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.070	0.930	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.070	0.930	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.070	0.930	0.000
T36 Poisoning by systemic antibiotics	0.070	0.930	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.070	0.930	0.000
T81 Complications of procedures, not elsewhere classified	0.070	0.930	0.000
T87 Complications peculiar to reattachment and amputation	0.070	0.930	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.069	0.930	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.069	0.931	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.069	0.931	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.068	0.931	0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.068	0.931	0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.068	0.931	0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.068	0.931	0.000
T51 Toxic effect of alcohol	0.068	0.932	0.000
S60-S69 Injuries to the wrist and hand	0.068	0.932	0.000
T86 Failure and rejection of transplanted organs and tissues	0.068	0.932	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.067	0.933	0.000
T91.8 Sequelae of other specified injuries of neck and trunk	0.067	0.933	0.000
T85.2 Mechanical complication of intraocular lens	0.067	0.933	0.000
T98 Sequelae of other and unspecified effects of external causes	0.066	0.933	0.000
T95 Sequelae of burns, corrosions and frostbite	0.066	0.933	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.066	0.933	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.066	0.933	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.066	0.933	0.000
S42.4 Fracture of lower end of humerus	0.066	0.934	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.066	0.934	0.000
T80 Complications following infusion, transfusion and therapeutic injection	0.066	0.934	0.000
S48 Traumatic amputation of shoulder and upper arm	0.066	0.934	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.066	0.934	0.000
S44 Injury of nerves at shoulder and upper arm level	0.066	0.934	0.000
S41 Open wound of shoulder and upper arm	0.066	0.934	0.000
S47 Crushing injury of shoulder and upper arm	0.066	0.934	0.000
T46.1 Calcium-channel blockers	0.066	0.934	0.000
S90-S99 Injuries to the ankle and foot	0.065	0.934	0.000
T13 Other injuries of lower limb, level unspecified	0.065	0.935	0.000
S40 Superficial injury of shoulder and upper arm	0.065	0.935	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.065	0.935	0.000
T90.9 Sequelae of unspecified injury of head	0.065	0.935	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.065	0.935	0.000
S70-S79 Injuries to the hip and thigh	0.065	0.935	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.065	0.935	0.000
T59 Toxic effect of other gases, fumes and vapours	0.065	0.935	0.000
T31 Burns classified according to extent of body surface involved	0.064	0.935	0.000
T43.9 Psychotropic drug, unspecified	0.064	0.936	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.064	0.936	0.000
T43.6 Psychostimulants with abuse potential	0.064	0.936	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.064	0.936	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.064	0.936	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.064	0.936	0.000
S32 Fracture of lumbar spine and pelvis	0.064	0.936	0.000
S20-S29 Injuries to the thorax	0.064	0.936	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.062	0.938	0.000
S37 Injury of urinary and pelvic organs	0.062	0.938	0.000
S36 Injury of intra-abdominal organs	0.062	0.938	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.062	0.938	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.062	0.938	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.062	0.938	0.000
S31 Open wound of abdomen, lower back and pelvis	0.062	0.938	0.000
T65 Toxic effect of other and unspecified substances	0.062	0.938	0.000
T62 Toxic effect of other noxious substances eaten as food	0.062	0.938	0.000
T61 Toxic effect of noxious substances eaten as seafood	0.062	0.938	0.000
T60 Toxic effect of pesticides	0.062	0.938	0.000
T57 Toxic effect of other inorganic substances	0.062	0.938	0.000
T56 Toxic effect of metals	0.062	0.938	0.000
T54 Toxic effect of corrosive substances	0.062	0.938	0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.062	0.938	0.000
T52 Toxic effect of organic solvents	0.062	0.938	0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.062	0.938	0.000
T58 Toxic effect of carbon monoxide	0.062	0.938	0.000
T55 Toxic effect of soaps and detergents	0.062	0.938	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.062	0.938	0.000
T90.2 Sequelae of fracture of skull and facial bones	0.061	0.938	0.000
S42.1 Fracture of scapula	0.061	0.939	0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.061	0.939	0.000
S42.9 Fracture of shoulder girdle, part unspecified	0.061	0.939	0.000
S42.8 Fracture of other parts of shoulder and upper arm	0.061	0.939	0.000
S42.7 Multiple fractures of clavicle, scapula and humerus	0.061	0.939	0.000
T23 Burn and corrosion of wrist and hand	0.061	0.939	0.000
T88.4 Failed or difficult intubation	0.061	0.939	0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.060	0.939	0.000
T63.4 Venom of other arthropods	0.060	0.939	0.000
T92.8 Sequelae of other specified injuries of upper limb	0.060	0.940	0.000
S30.1 Contusion of abdominal wall	0.060	0.940	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.060	0.940	0.000
S42.3 Fracture of shaft of humerus	0.060	0.940	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.060	0.940	0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.060	0.940	0.000
S30.0 Contusion of lower back and pelvis	0.059	0.941	0.000
T90.8 Sequelae of other specified injuries of head	0.059	0.941	0.000
T90.5 Sequelae of intracranial injury	0.059	0.941	0.000
T90.3 Sequelae of injury of cranial nerves	0.059	0.941	0.000
T90.1 Sequelae of open wound of head	0.059	0.941	0.000
T90.0 Sequelae of superficial injury of head	0.059	0.941	0.000
S68 Traumatic amputation of wrist and hand	0.059	0.941	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.059	0.941	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.059	0.941	0.000
T46.7 Peripheral vasodilators	0.059	0.941	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.059	0.941	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.059	0.941	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.059	0.941	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.059	0.941	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.059	0.941	0.000
T93 Sequelae of injuries of lower limb	0.058	0.941	0.000
S42.21 Fracture of upper end of humerus (open)	0.058	0.942	0.000
S50-S59 Injuries to the elbow and forearm	0.058	0.942	0.000
S10 Superficial injury of neck	0.058	0.942	0.000
T81.8 Other complications of procedures, not elsewhere classified	0.058	0.942	0.000
T81.4 Infection following a procedure, not elsewhere classified	0.058	0.942	0.000
T32 Corrosions classified according to extent of body surface involved	0.057	0.943	0.000
T30 Burn and corrosion, body region unspecified	0.057	0.943	0.000
T29 Burns and corrosions of multiple body regions	0.057	0.943	0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.057	0.943	0.000
T50.8 Diagnostic agents	0.056	0.943	0.000
T50.7 Analeptics and opioid receptor antagonists	0.056	0.943	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.056	0.943	0.000
T50.5 Appetite depressants	0.056	0.943	0.000
T50.4 Drugs affecting uric acid metabolism	0.056	0.943	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.056	0.943	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.056	0.943	0.000
T50.1 Loop [high-ceiling] diuretics	0.056	0.943	0.000
T50.0 Mineralocorticoids and their antagonists	0.056	0.943	0.000
T13.0 Superficial injury of lower limb, level unspecified	0.056	0.944	0.000
T11 Other injuries of upper limb, level unspecified	0.056	0.944	0.000
T09 Other injuries of spine and trunk, level unspecified	0.056	0.944	0.000
T12.X1 Fracture of lower limb, level unspecified (open)	0.056	0.944	0.000
T12.X0 Fracture of lower limb, level unspecified (closed)	0.056	0.944	0.000
T12 Fracture of lower limb, level unspecified	0.056	0.944	0.000
T10.X1 Fracture of upper limb, level unspecified (open)	0.056	0.944	0.000
T10.X0 Fracture of upper limb, level unspecified (closed)	0.056	0.944	0.000
T10 Fracture of upper limb, level unspecified	0.056	0.944	0.000
T08.X1 Fracture of spine, level unspecified (open)	0.056	0.944	0.000
T08.X0 Fracture of spine, level unspecified (closed)	0.056	0.944	0.000
T08 Fracture of spine, level unspecified	0.056	0.944	0.000
T78 Adverse effects, not elsewhere classified	0.056	0.944	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.056	0.944	0.000
T91.9 Sequelae of unspecified injury of neck and trunk	0.056	0.944	0.000
T91.5 Sequelae of injury of intra-abdominal and pelvic organs	0.056	0.944	0.000
T91.4 Sequelae of injury of intrathoracic organs	0.056	0.944	0.000
T91.3 Sequelae of injury of spinal cord	0.056	0.944	0.000
T91.2 Sequelae of other fracture of thorax and pelvis	0.056	0.944	0.000
T91.1 Sequelae of fracture of spine	0.056	0.944	0.000
T91.0 Sequelae of superficial injury and open wound of neck and trunk	0.056	0.944	0.000
T25 Burn and corrosion of ankle and foot	0.055	0.945	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.055	0.945	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.055	0.945	0.000
T21 Burn and corrosion of trunk	0.055	0.945	0.000
T20 Burn and corrosion of head and neck	0.055	0.945	0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified	0.055	0.945	0.000
S19 Other and unspecified injuries of neck	0.055	0.945	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.055	0.945	0.000
S00-S09 Injuries to the head	0.055	0.945	0.000
T92.1 Sequelae of fracture of arm	0.055	0.945	0.000
T88.9 Complication of surgical and medical care, unspecified	0.055	0.945	0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.055	0.945	0.000
T88.5 Other complications of anaesthesia	0.055	0.945	0.000
T88.3 Malignant hyperthermia due to anaesthesis	0.055	0.945	0.000
T88.2 Shock due to anaesthesia	0.055	0.945	0.000
T88.1 Other complications following immunisation, not elsewhere classified	0.055	0.945	0.000
T88.0 Infection following immunisation	0.055	0.945	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.054	0.945	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.054	0.945	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.054	0.945	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.054	0.945	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.054	0.945	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.054	0.945	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.054	0.945	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.054	0.945	0.000
T44.0 Anticholinesterase agents	0.054	0.945	0.000
T51.0 Ethanol	0.054	0.945	0.000
S17 Crushing injury of neck	0.054	0.946	0.000
S15 Injury of blood vessels at neck level	0.054	0.946	0.000
S14 Injury of nerves and spinal cord at neck level	0.054	0.946	0.000
S11 Open wound of neck	0.054	0.946	0.000
S18 Traumatic amputation at neck level	0.054	0.946	0.000
S16 Injury of muscle and tendon at neck level	0.054	0.946	0.000
S60 Superficial injury of wrist and hand	0.054	0.946	0.000
T31.0 Burns involving less than 10% of body surface	0.054	0.946	0.000
T79.8 Other early complications of trauma	0.054	0.946	0.000
S67 Crushing injury of wrist and hand	0.054	0.946	0.000
T92.9 Sequelae of unspecified injury of upper limb	0.054	0.946	0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.054	0.946	0.000
T92.4 Sequelae of injury of nerve of upper limb	0.054	0.946	0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.054	0.946	0.000
T92.0 Sequelae of open wound of upper limb	0.054	0.946	0.000
S42.40 Fracture of lower end of humerus (closed)	0.053	0.946	0.000
T75 Effects of other external causes	0.053	0.946	0.000
T74 Maltreatment syndromes	0.053	0.946	0.000
T73 Effects of other deprivation	0.053	0.946	0.000
T70 Effects of air pressure and water pressure	0.053	0.946	0.000
T69 Other effects of reduced temperature	0.053	0.946	0.000
T67 Effects of heat and light	0.053	0.946	0.000
T71 Asphyxiation	0.053	0.946	0.000
T68 Hypothermia	0.053	0.946	0.000
T66 Unspecified effects of radiation	0.053	0.946	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.053	0.947	0.000
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis	0.053	0.947	0.000
S30.2 Contusion of external genital organs	0.053	0.947	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.053	0.947	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.053	0.947	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.053	0.947	0.000
T42.3 Barbiturates	0.053	0.947	0.000
T42.2 Succinimides and oxazolidinediones	0.053	0.947	0.000
T42.1 Iminostilbenes	0.053	0.947	0.000
T42.0 Hydantoin derivatives	0.053	0.947	0.000
S43.0 Dislocation of shoulder joint	0.053	0.947	0.000
T87.6 Other and unspecified complications of amputation stump	0.053	0.947	0.000
S32.5 Fracture of pubis	0.053	0.947	0.000
S12 Fracture of neck	0.053	0.947	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.053	0.947	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.053	0.947	0.000
T39.4 Antirheumatics, not elsewhere classified	0.053	0.947	0.000
T39.2 Pyrazolone derivatives	0.053	0.947	0.000
T88.7 Unspecified adverse effect of drug or medicament	0.053	0.947	0.000
T38.9 Other and unspecified hormone antagonists	0.052	0.947	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.052	0.947	0.000
T38.7 Androgens and anabolic congeners	0.052	0.947	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.052	0.947	0.000
T38.5 Other oestrogens and progestogens	0.052	0.947	0.000
T38.4 Oral contraceptives	0.052	0.947	0.000
T38.2 Antithyroid drugs	0.052	0.947	0.000
T38.1 Thyroid hormones and substitutes	0.052	0.947	0.000
T38.0 Glucocorticoids and synthetic analogues	0.052	0.947	0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.052	0.948	0.000
T14 Injury of unspecified body region	0.052	0.948	0.000
S46.0 Injury of tendon of the rotator cuff of shoulder	0.052	0.948	0.000
T81.7 Vascular complications following a procedure, not elsewhere classified	0.052	0.948	0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.052	0.948	0.000
T17 Foreign body in respiratory tract	0.052	0.948	0.000
T06 Other injuries involving multiple body regions, not elsewhere classified	0.051	0.948	0.000
T05 Traumatic amputations involving multiple body regions	0.051	0.948	0.000
T04 Crushing injuries involving multiple body regions	0.051	0.948	0.000
T03 Dislocations, sprains and strains involving multiple body regions	0.051	0.948	0.000
T02 Fractures involving multiple body regions	0.051	0.948	0.000
T01 Open wounds involving multiple body regions	0.051	0.948	0.000
T00 Superficial injuries involving multiple body regions	0.051	0.948	0.000
T07 Unspecified multiple injuries	0.051	0.948	0.000
T28 Burn and corrosion of other internal organs	0.051	0.948	0.000
T27 Burn and corrosion of respiratory tract	0.051	0.948	0.000
T26 Burn and corrosion confined to eye and adnexa	0.051	0.948	0.000
T35 Frostbite involving multiple body regions and unspecified frostbite	0.051	0.948	0.000
T34 Frostbite with tissue necrosis	0.051	0.948	0.000
T33 Superficial frostbite	0.051	0.948	0.000
T45.0 Antiallergic and antiemetic drugs	0.051	0.949	0.000
T39.1 4-Aminophenol derivatives	0.051	0.949	0.000
T63.9 Toxic effect of contact with unspecified venomous animal	0.051	0.949	0.000
T63.8 Toxic effect of contact with other venomous animals	0.051	0.949	0.000
T63.6 Toxic effect of contact with other marine animals	0.051	0.949	0.000
T63.5 Toxic effect of contact with fish	0.051	0.949	0.000
T63.3 Venom of spider	0.051	0.949	0.000
T63.2 Venom of scorpion	0.051	0.949	0.000
T63.1 Venom of other reptiles	0.051	0.949	0.000
T63.0 Snake venom	0.051	0.949	0.000
T51.9 Alcohol, unspecified	0.051	0.949	0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.051	0.949	0.000
T79.7 Traumatic subcutaneous emphysema	0.051	0.949	0.000
T79.3 Post-traumatic wound infection, not elsewhere classified	0.051	0.949	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.051	0.949	0.000
T45.8 Other primarily systemic and haematological agents	0.051	0.949	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.051	0.949	0.000
T45.6 Fibrinolysis-affecting drugs	0.051	0.949	0.000
T45.5 Anticoagulants	0.051	0.949	0.000
T45.4 Iron and its compounds	0.051	0.949	0.000
T45.3 Enzymes, not elsewhere classified	0.051	0.949	0.000
T45.2 Vitamins, not elsewhere classified	0.051	0.949	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.051	0.949	0.000
S62 Fracture at wrist and hand level	0.051	0.949	0.000
I44 Atrioventricular and left bundle-branch block	0.000	0.949	0.050
T36.9 Systemic antibiotic, unspecified	0.051	0.949	0.000
T36.8 Other systemic antibiotics	0.051	0.949	0.000
T36.7 Antifungal antibiotics, systemically used	0.051	0.949	0.000
T36.6 Rifamycins	0.051	0.949	0.000
T36.5 Aminoglycosides	0.051	0.949	0.000
T36.4 Tetracyclines	0.051	0.949	0.000
T36.3 Macrolides	0.051	0.949	0.000
T36.2 Chloramphenicol group	0.051	0.949	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.051	0.949	0.000
T36.0 Penicillins	0.051	0.949	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.051	0.949	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.051	0.949	0.000
T37.5 Antiviral drugs	0.051	0.949	0.000
T37.4 Anthelminthics	0.051	0.949	0.000
T37.3 Other antiprotozoal drugs	0.051	0.949	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.051	0.949	0.000
T37.1 Antimycobacterial drugs	0.051	0.949	0.000
T37.0 Sulphonamides	0.051	0.949	0.000
T41.5 Therapeutic gases	0.051	0.949	0.000
T41.4 Anaesthetic, unspecified	0.051	0.949	0.000
T41.3 Local anaesthetics	0.051	0.949	0.000
T41.2 Other and unspecified general anaesthetics	0.051	0.949	0.000
T41.1 Intravenous anaesthetics	0.051	0.949	0.000
T41.0 Inhaled anaesthetics	0.051	0.949	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.051	0.949	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.051	0.949	0.000
T47.7 Emetics	0.051	0.949	0.000
T47.6 Antidiarrhoeal drugs	0.051	0.949	0.000
T47.5 Digestants	0.051	0.949	0.000
T47.4 Other laxatives	0.051	0.949	0.000
T47.3 Saline and osmotic laxatives	0.051	0.949	0.000
T47.2 Stimulant laxatives	0.051	0.949	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.051	0.949	0.000
T47.0 Histamine H(2)-receptor antagonists	0.051	0.949	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.051	0.949	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.051	0.949	0.000
T48.5 Anti-common-cold drugs	0.051	0.949	0.000
T48.4 Expectorants	0.051	0.949	0.000
T48.3 Antitussives	0.051	0.949	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.051	0.949	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.051	0.949	0.000
T48.0 Oxytocic drugs	0.051	0.949	0.000
T49.9 Topical agent, unspecified	0.051	0.949	0.000
T49.8 Other topical agents	0.051	0.949	0.000
T49.7 Dental drugs, topically applied	0.051	0.949	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.051	0.949	0.000
T49.5 Ophthalmological drugs and preparations	0.051	0.949	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.051	0.949	0.000
T49.3 Emollients, demulcents and protectants	0.051	0.949	0.000
T49.2 Local astringents and local detergents	0.051	0.949	0.000
T49.1 Antipruritics	0.051	0.949	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.051	0.949	0.000
S71 Open wound of hip and thigh	0.050	0.949	0.000
S91 Open wound of ankle and foot	0.050	0.949	0.000
T81.9 Unspecified complication of procedure	0.050	0.949	0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure	0.050	0.950	0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure	0.050	0.950	0.000
T87.5 Necrosis of amputation stump	0.050	0.950	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations