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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117513935
log Bayes Factor = 14.1355
Chromosome 22   position 32,923,673  (GRCh37) Explore rs117513935 on Ensembl!
Variant rs117513935 is part of Cluster X0162

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
0.999 0.001 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.998 0.002 0.000
M70-M79 Other soft tissue disorders
0.995 0.005 0.000
Chapter XX External causes of morbidity and mortality
0.994 0.006 0.000
Chapter VII Diseases of the eye and adnexa
0.993 0.007 0.000
M05-M14 Inflammatory polyarthropathies
0.992 0.008 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.991 0.009 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.987 0.013 0.000
M75 Shoulder lesions
0.986 0.014 0.000
N73 Other female pelvic inflammatory diseases
0.986 0.014 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.982 0.018 0.000
Z36 Antenatal screening
0.981 0.019 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.979 0.021 0.000
N73.6 Female pelvic peritoneal adhesions
0.979 0.021 0.000
M50-M54 Other dorsopathies
0.976 0.024 0.000
M06 Other rheumatoid arthritis
0.970 0.030 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.968 0.032 0.000
H25-H28 Disorders of lens
0.965 0.035 0.000
M54 Dorsalgia
0.965 0.035 0.000
K65-K67 Diseases of peritoneum
0.964 0.036 0.000
M54.5 Low back pain
0.956 0.044 0.000
N25-N29 Other disorders of kidney and ureter
0.952 0.048 0.000
M06.9 Rheumatoid arthritis, unspecified
0.952 0.048 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.949 0.051 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.938 0.062 0.000
Y43 Primarily systemic agents
0.937 0.063 0.000
K55-K64 Other diseases of intestines
0.933 0.067 0.000
M75.1 Rotator cuff syndrome
0.931 0.069 0.000
Z36.9 Antenatal screening, unspecified
0.928 0.072 0.000
K80 Cholelithiasis
0.926 0.074 0.000
H43-H45 Disorders of vitreous body and globe
0.926 0.074 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.925 0.075 0.000
Z03.4 Observation for suspected myocardial infarction
0.923 0.077 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.920 0.080 0.000
N75 Diseases of Bartholin's gland
0.918 0.082 0.000
K83 Other diseases of biliary tract
0.917 0.083 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.910 0.090 0.000
Z29 Need for other prophylactic measures
0.909 0.091 0.000
N30-N39 Other diseases of urinary system
0.908 0.092 0.000
K66 Other disorders of peritoneum
0.907 0.093 0.000
Chapter X Diseases of the respiratory system
0.907 0.093 0.000
H30-H36 Disorders of choroid and retina
0.906 0.094 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.905 0.095 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.904 0.096 0.000
N76 Other inflammation of vagina and vulva
0.900 0.100 0.000
Y43.3 Other antineoplastic drugs
0.899 0.101 0.000
Z03.9 Observation for suspected disease or condition, unspecified
0.897 0.103 0.000
N60-N64 Disorders of breast
0.897 0.103 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.895 0.105 0.000
K59 Other functional intestinal disorders
0.894 0.106 0.000
H25 Senile cataract
0.889 0.111 0.000
M54.59 Low back pain (Site unspecified)
0.888 0.112 0.000
Z31 Procreative management
0.888 0.112 0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis
0.885 0.115 0.000
M54.57 Low back pain (Lumbosacral region)
0.885 0.115 0.000
H43 Disorders of vitreous body
0.881 0.119 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.878 0.122 0.000
N80 Endometriosis
0.877 0.123 0.000
H35 Other retinal disorders
0.875 0.125 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.873 0.127 0.000
Z04 Examination and observation for other reasons
0.872 0.128 0.000
Z29.2 Other prophylactic chemotherapy
0.869 0.131 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.869 0.131 0.000
W20-W49 Exposure to inanimate mechanical forces
0.868 0.132 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.868 0.132 0.000
M45-M49 Spondylopathies
0.867 0.133 0.000
K63 Other diseases of intestine
0.867 0.133 0.000
E20-E35 Disorders of other endocrine glands
0.863 0.137 0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods
0.860 0.140 0.000
H26 Other cataract
0.856 0.144 0.000
K66.0 Peritoneal adhesions
0.855 0.145 0.000
M13 Other arthritis
0.854 0.146 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.854 0.146 0.000
W00-W19 Falls
0.850 0.150 0.000
S20-S29 Injuries to the thorax
0.849 0.151 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.847 0.153 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.847 0.153 0.000
E70-E90 Metabolic disorders
0.846 0.154 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.844 0.156 0.000
Z30 Contraceptive management
0.844 0.156 0.000
K65 Peritonitis
0.842 0.158 0.000
M75.5 Bursitis of shoulder
0.842 0.158 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.840 0.160 0.000
M75.0 Adhesive capsulitis of shoulder
0.839 0.161 0.000
K63.8 Other specified diseases of intestine
0.838 0.162 0.000
N87 Dysplasia of cervix uteri
0.837 0.163 0.000
M71 Other bursopathies
0.836 0.164 0.000
M75.3 Calcific tendinitis of shoulder
0.836 0.164 0.000
N28.1 Cyst of kidney, acquired
0.834 0.166 0.000
J30-J39 Other diseases of upper respiratory tract
0.833 0.167 0.000
O80-O84 Delivery
0.832 0.168 0.000
K59.0 Constipation
0.831 0.169 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.830 0.170 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.830 0.170 0.000
N80.1 Endometriosis of ovary
0.829 0.171 0.000
N71 Inflammatory disease of uterus, except cervix
0.829 0.171 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.828 0.172 0.000
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods
0.824 0.176 0.000
N62 Hypertrophy of breast
0.823 0.177 0.000
K83.0 Cholangitis
0.822 0.178 0.000
H25.8 Other senile cataract
0.820 0.180 0.000
M80-M85 Disorders of bone density and structure
0.820 0.180 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.819 0.181 0.000
K80.2 Calculus of gallbladder without cholecystitis
0.818 0.182 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.816 0.184 0.000
N75.0 Cyst of Bartholin's gland
0.815 0.185 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.814 0.186 0.000
K70-K77 Diseases of liver
0.812 0.188 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.812 0.188 0.000
Z36.8 Other antenatal screening
0.812 0.188 0.000
H25.0 Senile incipient cataract
0.811 0.189 0.000
S90-S99 Injuries to the ankle and foot
0.806 0.194 0.000
N70 Salpingitis and oophoritis
0.806 0.194 0.000
K63.3 Ulcer of intestine
0.804 0.196 0.000
T66-T78 Other and unspecified effects of external causes
0.803 0.197 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.802 0.198 0.000
M07 Psoriatic and enteropathic arthropathies
0.799 0.201 0.000
N83.3 Acquired atrophy of ovary and Fallopian tube
0.799 0.201 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.795 0.205 0.000
H43.3 Other vitreous opacities
0.794 0.206 0.000
Z03.6 Observation for suspected toxic effect from ingested substance
0.793 0.207 0.000
N76.0 Acute vaginitis
0.792 0.208 0.000
M77 Other enthesopathies
0.792 0.208 0.000
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.791 0.209 0.000
Z36.2 Other antenatal screening based on amniocentesis
0.790 0.210 0.000
E83 Disorders of mineral metabolism
0.790 0.210 0.000
K82 Other diseases of gallbladder
0.790 0.210 0.000
K08 Other disorders of teeth and supporting structures
0.788 0.212 0.000
M54.56 Low back pain (Lumbar region)
0.787 0.213 0.000
M10 Gout
0.784 0.216 0.000
K40-K46 Hernia
0.783 0.217 0.000
H27 Other disorders of lens
0.782 0.218 0.000
Y43.0 Antiallergic and antiemetic drugs
0.781 0.219 0.000
M54.1 Radiculopathy
0.779 0.221 0.000
S80-S89 Injuries to the knee and lower leg
0.779 0.221 0.000
O80 Single spontaneous delivery
0.778 0.222 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.776 0.224 0.000
K70 Alcoholic liver disease
0.774 0.226 0.000
Chapter VI Diseases of the nervous system
0.774 0.226 0.000
H35.3 Degeneration of macula and posterior pole
0.774 0.226 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.773 0.227 0.000
N75.1 Abscess of Bartholin's gland
0.773 0.227 0.000
M53 Other dorsopathies, not elsewhere classified
0.773 0.227 0.000
Z30.2 Sterilisation
0.769 0.231 0.000
Z71.8 Other specified counselling
0.769 0.231 0.000
N39 Other disorders of urinary system
0.769 0.231 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.768 0.232 0.000
N60 Benign mammary dysplasia
0.768 0.232 0.000
N87.1 Moderate cervical dysplasia
0.767 0.233 0.000
M13.9 Arthritis, unspecified
0.767 0.233 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.766 0.233 0.000
H55-H59 Other disorders of eye and adnexa
0.764 0.236 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.763 0.237 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.763 0.237 0.000
T81 Complications of procedures, not elsewhere classified
0.763 0.237 0.000
Z45 Adjustment and management of implanted device
0.761 0.239 0.000
Z04.8 Examination and observation for other specified reasons
0.761 0.239 0.000
Y52 Agents primarily affecting the cardiovascular system
0.761 0.239 0.000
Chapter VIII Diseases of the ear and mastoid process
0.761 0.239 0.000
M54.50 Low back pain (Multiple sites in spine)
0.761 0.239 0.000
N36 Other disorders of urethra
0.760 0.240 0.000
E86 Volume depletion
0.760 0.240 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.759 0.241 0.000
M79.0 Rheumatism, unspecified
0.757 0.243 0.000
K42 Umbilical hernia
0.757 0.243 0.000
Z04.9 Examination and observation for unspecified reason
0.757 0.243 0.000
E83.5 Disorders of calcium metabolism
0.756 0.244 0.000
K12 Stomatitis and related lesions
0.756 0.244 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.756 0.244 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.755 0.245 0.000
V20-V29 Motorcycle rider injured in transport accident
0.755 0.245 0.000
M91-M94 Chondropathies
0.754 0.246 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.754 0.246 0.000
N28.0 Ischaemia and infarction of kidney
0.753 0.247 0.000
W50-W64 Exposure to animate mechanical forces
0.753 0.247 0.000
M11 Other crystal arthropathies
0.753 0.247 0.000
M20-M25 Other joint disorders
0.751 0.249 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.748 0.252 0.000
N80.8 Other endometriosis
0.747 0.253 0.000
M54.3 Sciatica
0.747 0.253 0.000
K83.1 Obstruction of bile duct
0.747 0.253 0.000
Z31.2 In vitro fertilisation
0.746 0.254 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.745 0.255 0.000
N34 Urethritis and urethral syndrome
0.744 0.256 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.744 0.256 0.000
S60-S69 Injuries to the wrist and hand
0.742 0.258 0.000
N64 Other disorders of breast
0.742 0.258 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.740 0.260 0.000
N80.3 Endometriosis of pelvic peritoneum
0.740 0.260 0.000
K42.9 Umbilical hernia without obstruction or gangrene
0.740 0.260 0.000
N26 Unspecified contracted kidney
0.739 0.260 0.000
M47 Spondylosis
0.739 0.261 0.000
K65.9 Peritonitis, unspecified
0.739 0.261 0.000
M75.4 Impingement syndrome of shoulder
0.739 0.261 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.738 0.262 0.000
N83.1 Corpus luteum cyst
0.738 0.262 0.000
T86 Failure and rejection of transplanted organs and tissues
0.737 0.263 0.000
S10-S19 Injuries to the neck
0.737 0.263 0.000
H35.8 Other specified retinal disorders
0.737 0.263 0.000
Z45.2 Adjustment and management of vascular access device
0.737 0.263 0.000
Z29.1 Prophylactic immunotherapy
0.737 0.263 0.000
M06.0 Seronegative rheumatoid arthritis
0.736 0.263 0.000
E50-E64 Other nutritional deficiencies
0.732 0.268 0.000
W22 Striking against or struck by other objects
0.732 0.268 0.000
K35-K38 Diseases of appendix
0.732 0.268 0.000
M85 Other disorders of bone density and structure
0.731 0.269 0.000
N83.2 Other and unspecified ovarian cysts
0.730 0.270 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.730 0.270 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.729 0.271 0.000
J35 Chronic diseases of tonsils and adenoids
0.729 0.271 0.000
H26.9 Cataract, unspecified
0.728 0.272 0.000
Q80-Q89 Other congenital malformations
0.728 0.272 0.000
K83.8 Other specified diseases of biliary tract
0.727 0.273 0.000
S20 Superficial injury of thorax
0.727 0.273 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.727 0.273 0.000
H43.9 Disorder of vitreous body, unspecified
0.726 0.274 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.726 0.274 0.000
J00-J06 Acute upper respiratory infections
0.725 0.275 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.723 0.277 0.000
Chapter V Mental and behavioural disorders
0.722 0.278 0.000
Chapter XXII Codes for special purposes
0.722 0.278 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.721 0.279 0.000
K85 Acute pancreatitis
0.720 0.280 0.000
N28.9 Disorder of kidney and ureter, unspecified
0.720 0.280 0.000
K08.9 Disorder of teeth and supporting structures, unspecified
0.720 0.280 0.000
E40-E46 Malnutrition
0.719 0.281 0.000
N76.3 Subacute and chronic vulvitis
0.719 0.281 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.719 0.281 0.000
H10-H13 Disorders of conjunctiva
0.718 0.281 0.000
Z31.0 Tuboplasty or vasoplasty after previous sterilisation
0.718 0.282 0.000
H35.6 Retinal haemorrhage
0.718 0.282 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.718 0.282 0.000
Z32 Pregnancy examination and test
0.718 0.282 0.000
N83.0 Follicular cyst of ovary
0.717 0.283 0.000
K66.1 Haemoperitoneum
0.717 0.283 0.000
Z43 Attention to artificial openings
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
H26.0 Infantile, juvenile and presenile cataract
0.716 0.284 0.000
W10 Fall on and from stairs and steps
0.716 0.284 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.715 0.284 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.716 0.284 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.715 0.285 0.000
K86 Other diseases of pancreas
0.715 0.285 0.000
Z09.9 Follow-up examination after unspecified treatment for other conditions
0.714 0.286 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.714 0.286 0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm
0.714 0.286 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.714 0.286 0.000
M76 Enthesopathies of lower limb, excluding foot
0.713 0.286 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.713 0.286 0.000
Y35-Y36 Legal intervention and operations of war
0.713 0.287 0.000
Y10-Y34 Event of undetermined intent
0.713 0.287 0.000
Y00-Y09 Assault
0.713 0.287 0.000
X85-X99 Assault
0.713 0.287 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.713 0.287 0.000
X50-X57 Overexertion, travel and privation
0.713 0.287 0.000
X30-X39 Exposure to forces of nature
0.713 0.287 0.000
X20-X29 Contact with venomous animals and plants
0.713 0.287 0.000
X10-X19 Contact with heat and hot substances
0.713 0.287 0.000
X00-X09 Exposure to smoke, fire and flames
0.713 0.287 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.713 0.287 0.000
W75-W84 Other accidental threats to breathing
0.713 0.287 0.000
W65-W74 Accidental drowning and submersion
0.713 0.287 0.000
V98-V99 Other and unspecified transport accidents
0.713 0.287 0.000
V95-V97 Air and space transport accidents
0.713 0.287 0.000
V90-V94 Water transport accidents
0.713 0.287 0.000
V80-V89 Other land transport accidents
0.713 0.287 0.000
V70-V79 Bus occupant injured in transport accident
0.713 0.287 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.713 0.287 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.713 0.287 0.000
V40-V49 Car occupant injured in transport accident
0.713 0.287 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.713 0.287 0.000
V01-V09 Pedestrian injured in transport accident
0.713 0.287 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.712 0.288 0.000
V10-V19 Pedal cyclist injured in transport accident
0.712 0.288 0.000
K59.3 Megacolon, not elsewhere classified
0.712 0.288 0.000
N89 Other noninflammatory disorders of vagina
0.711 0.289 0.000
M14 Arthropathies in other diseases classified elsewhere
0.711 0.289 0.000
M12 Other specific arthropathies
0.711 0.289 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.711 0.289 0.000
M08 Juvenile arthritis
0.711 0.289 0.000
Z38 Liveborn infants according to place of birth
0.710 0.290 0.000
X60-X84 Intentional self-harm
0.710 0.290 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.710 0.290 0.000
E21.3 Hyperparathyroidism, unspecified
0.709 0.291 0.000
N39.8 Other specified disorders of urinary system
0.709 0.291 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.709 0.291 0.000
H35.0 Background retinopathy and retinal vascular changes
0.708 0.292 0.000
K50-K52 Noninfective enteritis and colitis
0.708 0.292 0.000
Z10 Routine general health check-up of defined subpopulation
0.707 0.292 0.000
M71.2 Synovial cyst of popliteal space [Baker]
0.708 0.292 0.000
O80.9 Single spontaneous delivery, unspecified
0.707 0.293 0.000
N39.4 Other specified urinary incontinence
0.707 0.293 0.000
E65-E68 Obesity and other hyperalimentation
0.707 0.293 0.000
M75.8 Other shoulder lesions
0.707 0.293 0.000
M75.9 Shoulder lesion, unspecified
0.707 0.293 0.000
M75.2 Bicipital tendinitis
0.707 0.293 0.000
N73.8 Other specified female pelvic inflammatory diseases
0.707 0.293 0.000
N73.5 Female pelvic peritonitis, unspecified
0.707 0.293 0.000
N73.4 Female chronic pelvic peritonitis
0.707 0.293 0.000
N73.3 Female acute pelvic peritonitis
0.707 0.293 0.000
N73.2 Unspecified parametritis and pelvic cellulitis
0.707 0.293 0.000
N73.1 Chronic parametritis and pelvic cellulitis
0.707 0.293 0.000
N73.0 Acute parametritis and pelvic cellulitis
0.707 0.293 0.000
K61 Abscess of anal and rectal regions
0.706 0.294 0.000
H43.1 Vitreous haemorrhage
0.706 0.294 0.000
M45 Ankylosing spondylitis
0.705 0.295 0.000
K59.8 Other specified functional intestinal disorders
0.705 0.295 0.000
Z33 Pregnant state, incidental
0.704 0.296 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.704 0.296 0.000
Z36.5 Antenatal screening for isoimmunisation
0.703 0.297 0.000
Z36.1 Antenatal screening for raised alphafetoprotein level
0.703 0.297 0.000
H21 Other disorders of iris and ciliary body
0.703 0.297 0.000
T33-T35 Frostbite
0.702 0.298 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.702 0.298 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.702 0.298 0.000
T00-T07 Injuries involving multiple body regions
0.702 0.298 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.701 0.298 0.000
T91 Sequelae of injuries of neck and trunk
0.701 0.299 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.701 0.299 0.000
N83.5 Torsion of ovary, ovarian pedicle and Fallopian tube
0.701 0.299 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.700 0.300 0.000
S70-S79 Injuries to the hip and thigh
0.700 0.300 0.000
Z01.6 Radiological examination, not elsewhere classified
0.699 0.301 0.000
K59.4 Anal spasm
0.698 0.301 0.000
M06.8 Other specified rheumatoid arthritis
0.695 0.304 0.000
M06.4 Inflammatory polyarthropathy
0.695 0.304 0.000
M06.3 Rheumatoid nodule
0.695 0.304 0.000
M06.2 Rheumatoid bursitis
0.695 0.304 0.000
M06.1 Adult-onset Still's disease
0.695 0.304 0.000
E21.0 Primary hyperparathyroidism
0.695 0.305 0.000
Z29.0 Isolation
0.694 0.306 0.000
Y59 Other and unspecified vaccines and biological substances
0.694 0.306 0.000
Y58 Bacterial vaccines
0.694 0.306 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.694 0.306 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.694 0.306 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.694 0.306 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.694 0.306 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.694 0.306 0.000
Y48 Anaesthetics and therapeutic gases
0.694 0.306 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.694 0.306 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.694 0.306 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.694 0.306 0.000
J60-J70 Lung diseases due to external agents
0.694 0.306 0.000
K55 Vascular disorders of intestine
0.694 0.306 0.000
Z73 Problems related to life-management difficulty
0.694 0.306 0.000
Z39 Postpartum care and examination
0.694 0.306 0.000
Z31.4 Procreative investigation and testing
0.693 0.307 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.692 0.308 0.000
M54.8 Other dorsalgia
0.692 0.308 0.000
M54.0 Panniculitis affecting regions of neck and back
0.692 0.308 0.000
O85-O92 Complications predominantly related to the puerperium
0.691 0.309 0.000
T87 Complications peculiar to reattachment and amputation
0.691 0.309 0.000
K67 Disorders of peritoneum in infectious diseases classified elsewhere
0.691 0.309 0.000
M25 Other joint disorders, not elsewhere classified
0.691 0.309 0.000
K90-K93 Other diseases of the digestive system
0.691 0.309 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.690 0.309 0.000
K82.8 Other specified diseases of gallbladder
0.690 0.310 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.690 0.310 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.689 0.311 0.000
K04 Diseases of pulp and periapical tissues
0.688 0.312 0.000
Y57 Other and unspecified drugs and medicaments
0.688 0.312 0.000
S92 Fracture of foot, except ankle
0.688 0.312 0.000
N76.4 Abscess of vulva
0.687 0.312 0.000
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm
0.687 0.313 0.000
M54.55 Low back pain (Thoracolumbar region)
0.685 0.315 0.000
M54.54 Low back pain-Thoracic
0.685 0.315 0.000
M54.53 Low back pain-Cervicothoracic
0.685 0.315 0.000
M54.52 Low back pain-Cervical
0.685 0.315 0.000
M54.51 Low back pain-Occipit-atl-axl
0.685 0.315 0.000
N00-N08 Glomerular diseases
0.684 0.316 0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere
0.683 0.317 0.000
N27 Small kidney of unknown cause
0.683 0.317 0.000
N25 Disorders resulting from impaired renal tubular function
0.683 0.317 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.682 0.317 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.682 0.317 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.682 0.317 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.682 0.317 0.000
N97 Female infertility
0.682 0.318 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.682 0.318 0.000
N32 Other disorders of bladder
0.682 0.318 0.000
N82 Fistulae involving female genital tract
0.681 0.319 0.000
N60.0 Solitary cyst of breast
0.681 0.319 0.000
H26.8 Other specified cataract
0.681 0.319 0.000
N83.9 Noninflammatory disorder of ovary, Fallopian tube and broad ligament, unspecified
0.681 0.319 0.000
Z03.2 Observation for suspected mental and behavioural disorders
0.681 0.319 0.000
Z03.0 Observation for suspected tuberculosis
0.681 0.319 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.680 0.320 0.000
N71.9 Inflammatory disease of uterus, unspecified
0.680 0.320 0.000
J81 Pulmonary oedema
0.679 0.321 0.000
H20 Iridocyclitis
0.679 0.321 0.000
Z29.8 Other specified prophylactic measures
0.678 0.322 0.000
M65-M68 Disorders of synovium and tendon
0.678 0.322 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.678 0.322 0.000
M51 Other intervertebral disk disorders
0.678 0.322 0.000
N28.8 Other specified disorders of kidney and ureter
0.678 0.322 0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm
0.678 0.322 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.678 0.322 0.000
S40-S49 Injuries to the shoulder and upper arm
0.678 0.322 0.000
T78 Adverse effects, not elsewhere classified
0.678 0.322 0.000
S29 Other and unspecified injuries of thorax
0.676 0.324 0.000
Z01.7 Laboratory examination
0.676 0.324 0.000
J39 Other diseases of upper respiratory tract
0.676 0.324 0.000
Y43.4 Immunosuppressive agents
0.676 0.324 0.000
E24 Cushing's syndrome
0.675 0.325 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.674 0.326 0.000
H65-H75 Diseases of middle ear and mastoid
0.674 0.326 0.000
Z43.2 Attention to ileostomy
0.674 0.326 0.000
W29 Contact with other powered hand tools and household machinery
0.673 0.327 0.000
Z28 Immunisation not carried out
0.672 0.328 0.000
Z27 Need for immunisation against combinations of infectious diseases
0.672 0.328 0.000
Z26 Need for immunisation against other single infectious diseases
0.672 0.328 0.000
Z25 Need for immunisation against other single viral diseases
0.672 0.328 0.000
Z24 Need for immunisation against certain single viral diseases
0.672 0.328 0.000
Z23 Need for immunisation against single bacterial diseases
0.672 0.328 0.000
Z20 Contact with and exposure to communicable diseases
0.672 0.328 0.000
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status
0.672 0.328 0.000
Y43.9 Primarily systemic agent, unspecified
0.672 0.328 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.672 0.328 0.000
Y43.6 Enzymes, not elsewhere classified
0.672 0.328 0.000
Y43.5 Acidifying and alkalising agents
0.672 0.328 0.000
Y43.2 Antineoplastic natural products
0.672 0.328 0.000
Y43.1 Antineoplastic antimetabolites
0.672 0.328 0.000
K11 Diseases of salivary glands
0.672 0.328 0.000
W25 Contact with sharp glass
0.670 0.330 0.000
K63.0 Abscess of intestine
0.669 0.331 0.000
M54.9 Dorsalgia, unspecified
0.669 0.331 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.669 0.331 0.000
N70.1 Chronic salpingitis and oophoritis
0.668 0.332 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.668 0.332 0.000
S82 Fracture of lower leg, including ankle
0.668 0.332 0.000
Z01.4 Gynaecological examination (general)(routine)
0.668 0.332 0.000
M85.8 Other specified disorders of bone density and structure
0.667 0.333 0.000
K59.9 Functional intestinal disorder, unspecified
0.667 0.333 0.000
J30 Vasomotor and allergic rhinitis
0.666 0.334 0.000
Y95 Nosocomial condition
0.666 0.334 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.665 0.335 0.000
H43.8 Other disorders of vitreous body
0.665 0.335 0.000
E29 Testicular dysfunction
0.665 0.335 0.000
K80.3 Calculus of bile duct with cholangitis
0.664 0.336 0.000
Z45.1 Adjustment and management of infusion pump
0.664 0.336 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.664 0.336 0.000
Z45.0 Adjustment and management of cardiac pacemaker
0.664 0.336 0.000
H25.9 Senile cataract, unspecified
0.663 0.337 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.663 0.337 0.000
H36 Retinal disorders in diseases classified elsewhere
0.663 0.337 0.000
M07.3 Other psoriatic arthropathies
0.662 0.338 0.000
K50 Crohn's disease [regional enteritis]
0.661 0.339 0.000
E27 Other disorders of adrenal gland
0.661 0.339 0.000
Z11.2 Special screening examination for other bacterial diseases
0.660 0.340 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.660 0.340 0.000
G20-G26 Extrapyramidal and movement disorders
0.659 0.341 0.000
J40-J47 Chronic lower respiratory diseases
0.659 0.341 0.000
O80.0 Spontaneous vertex delivery
0.658 0.342 0.000
N75.9 Disease of Bartholin's gland, unspecified
0.658 0.342 0.000
N75.8 Other diseases of Bartholin's gland
0.658 0.342 0.000
K83.9 Disease of biliary tract, unspecified
0.658 0.342 0.000
K83.5 Biliary cyst
0.658 0.342 0.000
K83.4 Spasm of sphincter of Oddi
0.658 0.342 0.000
K83.3 Fistula of bile duct
0.658 0.342 0.000
K83.2 Perforation of bile duct
0.658 0.342 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.657 0.342 0.000
Y44 Agents primarily affecting blood constituents
0.657 0.343 0.000
Z12 Special screening examination for neoplasms
0.657 0.343 0.000
M54.4 Lumbago with sciatica
0.657 0.343 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.657 0.343 0.000
Z30.1 Insertion of (intra-uterine) contraceptive device
0.656 0.343 0.000
M40-M43 Deforming dorsopathies
0.656 0.344 0.000
N87.9 Dysplasia of cervix uteri, unspecified
0.655 0.344 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.655 0.345 0.000
M54.6 Pain in thoracic spine
0.655 0.345 0.000
E85 Amyloidosis
0.655 0.345 0.000
K70.9 Alcoholic liver disease, unspecified
0.654 0.346 0.000
T82.3 Mechanical complication of other vascular grafts
0.653 0.346 0.000
G51 Facial nerve disorders
0.652 0.348 0.000
Z29.9 Prophylactic measure, unspecified
0.652 0.348 0.000
T82.1 Mechanical complication of cardiac electronic device
0.652 0.348 0.000
K70.1 Alcoholic hepatitis
0.652 0.348 0.000
N37 Urethral disorders in diseases classified elsewhere
0.651 0.349 0.000
N33 Bladder disorders in diseases classified elsewhere
0.651 0.349 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.651 0.349 0.000
M86-M90 Other osteopathies
0.650 0.350 0.000
K66.9 Disorder of peritoneum, unspecified
0.650 0.350 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.650 0.350 0.000
H31 Other disorders of choroid
0.650 0.350 0.000
H30 Chorioretinal inflammation
0.650 0.350 0.000
E88 Other metabolic disorders
0.650 0.350 0.000
N98 Complications associated with artificial fertilisation
0.649 0.351 0.000
N91 Absent, scanty and rare menstruation
0.649 0.351 0.000
N96 Habitual aborter
0.649 0.351 0.000
H35.4 Peripheral retinal degeneration
0.648 0.352 0.000
Z34 Supervision of normal pregnancy
0.648 0.352 0.000
H44 Disorders of globe
0.648 0.352 0.000
J35.1 Hypertrophy of tonsils
0.647 0.353 0.000
M79.2 Neuralgia and neuritis, unspecified
0.647 0.353 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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