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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117525990
log Bayes Factor = 11.468
Chromosome 10   position 106,848,064  (GRCh37) Explore rs117525990 on Ensembl!
Variant rs117525990 is part of Cluster X0243

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
M50-M54 Other dorsopathies
0.999 0.001 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.998 0.002 0.000
M54 Dorsalgia
0.995 0.005 0.000
M45-M49 Spondylopathies
0.995 0.005 0.000
D00-D09 In situ neoplasms
0.993 0.007 0.000
D10-D36 Benign neoplasms
0.992 0.008 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.988 0.012 0.000
Chapter IX Diseases of the circulatory system
0.988 0.012 0.000
Chapter XI Diseases of the digestive system
0.986 0.014 0.000
M40-M43 Deforming dorsopathies
0.985 0.015 0.000
M48 Other spondylopathies
0.981 0.019 0.000
C50-C50 Malignant neoplasm of breast
0.978 0.022 0.000
Chapter VII Diseases of the eye and adnexa
0.975 0.025 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.971 0.029 0.000
M48.0 Spinal stenosis
0.967 0.033 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.966 0.034 0.000
M51 Other intervertebral disk disorders
0.965 0.035 0.000
M54.9 Dorsalgia, unspecified
0.964 0.036 0.000
C50 Malignant neoplasm of breast
0.963 0.037 0.000
M43 Other deforming dorsopathies
0.957 0.043 0.000
I30-I52 Other forms of heart disease
0.955 0.045 0.000
K04 Diseases of pulp and periapical tissues
0.955 0.045 0.000
M54.5 Low back pain
0.954 0.046 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.954 0.046 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.954 0.046 0.000
O60-O75 Complications of labour and delivery
0.954 0.046 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.953 0.047 0.000
M48.06 Spinal stenosis (Lumbar region)
0.949 0.051 0.000
Chapter V Mental and behavioural disorders
0.942 0.058 0.000
C50.4 Upper-outer quadrant of breast
0.941 0.059 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.939 0.061 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.937 0.063 0.000
H30-H36 Disorders of choroid and retina
0.936 0.064 0.000
M43.1 Spondylolisthesis
0.935 0.065 0.000
D05 Carcinoma in situ of breast
0.935 0.065 0.000
H52 Disorders of refraction and accommodation
0.934 0.066 0.000
D23 Other benign neoplasms of skin
0.931 0.069 0.000
O36 Maternal care for other known or suspected foetal problems
0.931 0.069 0.000
M51.2 Other specified intervertebral disk displacement
0.925 0.075 0.000
H33 Retinal detachments and breaks
0.924 0.076 0.000
M54.59 Low back pain (Site unspecified)
0.924 0.076 0.000
I60-I69 Cerebrovascular diseases
0.923 0.077 0.000
K70-K77 Diseases of liver
0.922 0.078 0.000
D04 Carcinoma in situ of skin
0.918 0.082 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.918 0.082 0.000
M43.16 Spondylolisthesis (Lumbar region)
0.916 0.084 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.909 0.091 0.000
H52.1 Myopia
0.904 0.096 0.000
I47 Paroxysmal tachycardia
0.903 0.097 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.897 0.103 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.896 0.104 0.000
K04.7 Periapical abscess without sinus
0.894 0.106 0.000
F30-F39 Mood [affective] disorders
0.890 0.110 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.889 0.111 0.000
C50.8 Overlapping lesion of breast
0.888 0.112 0.000
D23.4 Skin of scalp and neck
0.884 0.116 0.000
D03 Melanoma in situ
0.884 0.116 0.000
M47 Spondylosis
0.883 0.117 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.881 0.119 0.000
M41 Scoliosis
0.881 0.119 0.000
H33.2 Serous retinal detachment
0.880 0.120 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.875 0.125 0.000
K86 Other diseases of pancreas
0.871 0.129 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.871 0.129 0.000
I85 Oesophageal varices
0.871 0.129 0.000
I87 Other disorders of veins
0.869 0.131 0.000
Q60-Q64 Congenital malformations of the urinary system
0.869 0.131 0.000
H55-H59 Other disorders of eye and adnexa
0.863 0.137 0.000
D22 Melanocytic naevi
0.860 0.140 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.856 0.144 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.855 0.145 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.853 0.147 0.000
D05.1 Intraductal carcinoma in situ
0.852 0.148 0.000
I47.2 Ventricular tachycardia
0.849 0.151 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.846 0.154 0.000
K12 Stomatitis and related lesions
0.846 0.154 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.846 0.154 0.000
S50-S59 Injuries to the elbow and forearm
0.845 0.155 0.000
C73 Malignant neoplasm of thyroid gland
0.844 0.156 0.000
C83.3 Large cell (diffuse)
0.843 0.157 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.834 0.166 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.833 0.167 0.000
I46 Cardiac arrest
0.833 0.167 0.000
K08 Other disorders of teeth and supporting structures
0.832 0.168 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.831 0.169 0.000
I84 Haemorrhoids
0.831 0.169 0.000
D25 Leiomyoma of uterus
0.829 0.171 0.000
D23.2 Skin of ear and external auricular canal
0.829 0.171 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.827 0.173 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.826 0.174 0.000
K70 Alcoholic liver disease
0.825 0.175 0.000
M48.09 Spinal stenosis (Site unspecified)
0.825 0.175 0.000
D45 Polycythaemia vera
0.824 0.176 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.820 0.180 0.000
I42 Cardiomyopathy
0.819 0.181 0.000
K85 Acute pancreatitis
0.818 0.182 0.000
O66 Other obstructed labour
0.816 0.184 0.000
O70 Perineal laceration during delivery
0.815 0.185 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.814 0.186 0.000
K90-K93 Other diseases of the digestive system
0.813 0.186 0.000
M51.9 Intervertebral disk disorder, unspecified
0.812 0.188 0.000
I67 Other cerebrovascular diseases
0.812 0.188 0.000
D26 Other benign neoplasms of uterus
0.810 0.190 0.000
O36.8 Maternal care for other specified foetal problems
0.809 0.191 0.000
I34 Nonrheumatic mitral valve disorders
0.808 0.192 0.000
M54.56 Low back pain (Lumbar region)
0.808 0.192 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.807 0.193 0.000
O32.1 Maternal care for breech presentation
0.807 0.193 0.000
K14 Diseases of tongue
0.807 0.193 0.000
M41.9 Scoliosis, unspecified
0.806 0.194 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.805 0.195 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.804 0.195 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.804 0.196 0.000
O32.3 Maternal care for face, brow and chin presentation
0.804 0.196 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.803 0.197 0.000
D05.9 Carcinoma in situ of breast, unspecified
0.802 0.198 0.000
H52.2 Astigmatism
0.801 0.199 0.000
D27 Benign neoplasm of ovary
0.801 0.199 0.000
D36 Benign neoplasm of other and unspecified sites
0.801 0.199 0.000
K04.8 Radicular cyst
0.799 0.201 0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress
0.798 0.202 0.000
M54.1 Radiculopathy
0.797 0.203 0.000
M60-M63 Disorders of muscles
0.795 0.205 0.000
M05-M14 Inflammatory polyarthropathies
0.794 0.206 0.000
D10 Benign neoplasm of mouth and pharynx
0.793 0.207 0.000
Chapter XX External causes of morbidity and mortality
0.792 0.208 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.792 0.208 0.000
O61 Failed induction of labour
0.791 0.209 0.000
S40-S49 Injuries to the shoulder and upper arm
0.789 0.210 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.789 0.211 0.000
F31 Bipolar affective disorder
0.787 0.213 0.000
M47.2 Other spondylosis with radiculopathy
0.787 0.213 0.000
I49 Other cardiac arrhythmias
0.785 0.215 0.000
C50.2 Upper-inner quadrant of breast
0.784 0.216 0.000
I85.9 Oesophageal varices without bleeding
0.784 0.216 0.000
K86.2 Cyst of pancreas
0.782 0.218 0.000
I84.9 Unspecified haemorrhoids without complication
0.782 0.218 0.000
K76 Other diseases of liver
0.781 0.219 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.781 0.219 0.000
D04.3 Skin of other and unspecified parts of face
0.780 0.220 0.000
F30 Manic episode
0.777 0.223 0.000
K04.4 Acute apical periodontitis of pulpal origin
0.777 0.223 0.000
M91-M94 Chondropathies
0.777 0.223 0.000
D06 Carcinoma in situ of cervix uteri
0.776 0.224 0.000
C34 Malignant neoplasm of bronchus and lung
0.776 0.224 0.000
H33.3 Retinal breaks without detachment
0.774 0.226 0.000
I81 Portal vein thrombosis
0.774 0.226 0.000
O36.6 Maternal care for excessive foetal growth
0.773 0.227 0.000
K86.9 Disease of pancreas, unspecified
0.772 0.228 0.000
K82 Other diseases of gallbladder
0.772 0.228 0.000
H33.5 Other retinal detachments
0.771 0.229 0.000
O32.8 Maternal care for other malpresentation of foetus
0.770 0.229 0.000
D22.7 Melanocytic naevi of lower limb, including hip
0.770 0.230 0.000
H43-H45 Disorders of vitreous body and globe
0.770 0.230 0.000
M46 Other inflammatory spondylopathies
0.769 0.231 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.768 0.232 0.000
K04.5 Chronic apical periodontitis
0.768 0.232 0.000
D04.7 Skin of lower limb, including hip
0.767 0.233 0.000
H57 Other disorders of eye and adnexa
0.764 0.236 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.764 0.236 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.762 0.238 0.000
I67.8 Other specified cerebrovascular diseases
0.761 0.239 0.000
M45 Ankylosing spondylitis
0.760 0.240 0.000
D03.6 Melanoma in situ of upper limb, including shoulder
0.757 0.243 0.000
O41 Other disorders of amniotic fluid and membranes
0.757 0.243 0.000
I65.2 Occlusion and stenosis of carotid artery
0.756 0.244 0.000
D25.0 Submucous leiomyoma of uterus
0.756 0.244 0.000
K83 Other diseases of biliary tract
0.755 0.245 0.000
D35.1 Parathyroid gland
0.755 0.245 0.000
K04.6 Periapical abscess with sinus
0.755 0.245 0.000
M00-M03 Infectious arthropathies
0.754 0.245 0.000
K92 Other diseases of digestive system
0.754 0.246 0.000
I61 Intracerebral haemorrhage
0.753 0.246 0.000
Q80-Q89 Other congenital malformations
0.753 0.247 0.000
O44 Placenta praevia
0.753 0.247 0.000
K85.1 Biliary acute pancreatitis
0.751 0.249 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.750 0.250 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.750 0.250 0.000
M86-M90 Other osteopathies
0.749 0.251 0.000
M41.96 Scoliosis, unspecified (Lumbar region)
0.748 0.252 0.000
M54.3 Sciatica
0.747 0.253 0.000
Q61 Cystic kidney disease
0.746 0.254 0.000
M65-M68 Disorders of synovium and tendon
0.746 0.254 0.000
I87.2 Venous insufficiency (chronic) (peripheral)
0.746 0.254 0.000
D13.1 Stomach
0.746 0.254 0.000
K08.3 Retained dental root
0.746 0.254 0.000
D04.6 Skin of upper limb, including shoulder
0.745 0.255 0.000
I82 Other venous embolism and thrombosis
0.744 0.256 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.744 0.256 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.744 0.256 0.000
K11 Diseases of salivary glands
0.743 0.257 0.000
F60-F69 Disorders of adult personality and behaviour
0.742 0.258 0.000
D17 Benign lipomatous neoplasm
0.742 0.258 0.000
C88 Malignant immunoproliferative diseases
0.741 0.259 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.740 0.260 0.000
M48.02 Spinal stenosis (Cervical region)
0.739 0.261 0.000
H52.3 Anisometropia and aniseikonia
0.738 0.262 0.000
O36.0 Maternal care for rhesus isoimmunisation
0.736 0.264 0.000
H33.1 Retinoschisis and retinal cysts
0.735 0.265 0.000
I33 Acute and subacute endocarditis
0.734 0.266 0.000
O70.1 Second degree perineal laceration during delivery
0.734 0.266 0.000
O62 Abnormalities of forces of labour
0.733 0.267 0.000
Q21 Congenital malformations of cardiac septa
0.733 0.267 0.000
H50 Other strabismus
0.732 0.268 0.000
M43.17 Spondylolisthesis (Lumbosacral region)
0.732 0.268 0.000
T79-T79 Certain early complications of trauma
0.731 0.268 0.000
S52 Fracture of forearm
0.731 0.269 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.731 0.269 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.731 0.269 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.730 0.270 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.729 0.271 0.000
D03.3 Melanoma in situ of other and unspecified parts of face
0.728 0.272 0.000
K12.2 Cellulitis and abscess of mouth
0.728 0.272 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.727 0.272 0.000
M54.4 Lumbago with sciatica
0.727 0.273 0.000
C50.0 Nipple and areola
0.727 0.273 0.000
O43 Placental disorders
0.726 0.274 0.000
K70.3 Alcoholic cirrhosis of liver
0.726 0.274 0.000
F99-F99 Unspecified mental disorder
0.725 0.275 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.725 0.275 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.723 0.277 0.000
I99 Other and unspecified disorders of circulatory system
0.723 0.277 0.000
I30 Acute pericarditis
0.722 0.278 0.000
M54.6 Pain in thoracic spine
0.721 0.279 0.000
I84.0 Internal thrombosed haemorrhoids
0.721 0.279 0.000
I84.1 Internal haemorrhoids with other complications
0.721 0.279 0.000
F25 Schizoaffective disorders
0.720 0.280 0.000
M54.2 Cervicalgia
0.720 0.280 0.000
Q50-Q56 Congenital malformations of genital organs
0.720 0.280 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.719 0.281 0.000
O34.1 Maternal care for tumour of corpus uteri
0.719 0.281 0.000
F20 Schizophrenia
0.719 0.281 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.719 0.281 0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified
0.718 0.282 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.717 0.282 0.000
I44 Atrioventricular and left bundle-branch block
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
O32.2 Maternal care for transverse and oblique lie
0.717 0.283 0.000
M06 Other rheumatoid arthritis
0.717 0.283 0.000
D21.2 Connective and other soft tissue of lower limb, including hip
0.716 0.284 0.000
I63 Cerebral infarction
0.716 0.284 0.000
O85-O92 Complications predominantly related to the puerperium
0.716 0.284 0.000
K14.0 Glossitis
0.715 0.285 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.714 0.286 0.000
C50.3 Lower-inner quadrant of breast
0.714 0.286 0.000
M54.8 Other dorsalgia
0.713 0.286 0.000
M54.0 Panniculitis affecting regions of neck and back
0.713 0.286 0.000
M49 Spondylopathies in diseases classified elsewhere
0.713 0.287 0.000
D22.1 Melanocytic naevi of eyelid, including canthus
0.713 0.287 0.000
H33.0 Retinal detachment with retinal break
0.713 0.287 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.712 0.288 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.712 0.288 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.712 0.288 0.000
I46.0 Cardiac arrest with successful resuscitation
0.712 0.288 0.000
S50 Superficial injury of forearm
0.711 0.289 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.711 0.289 0.000
D31 Benign neoplasm of eye and adnexa
0.711 0.289 0.000
D30 Benign neoplasm of urinary organs
0.711 0.289 0.000
D29 Benign neoplasm of male genital organs
0.711 0.289 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.711 0.289 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.711 0.289 0.000
D19 Benign neoplasm of mesothelial tissue
0.711 0.289 0.000
D16 Benign neoplasm of bone and articular cartilage
0.711 0.289 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.711 0.289 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.711 0.289 0.000
C97 Malignant neoplasms of independent (primary) multiple sites
0.709 0.291 0.000
I87.8 Other specified disorders of veins
0.709 0.291 0.000
D23.5 Skin of trunk
0.709 0.291 0.000
O45 Premature separation of placenta [abruptio placentae]
0.709 0.291 0.000
O33 Maternal care for known or suspected disproportion
0.709 0.291 0.000
O31 Complications specific to multiple gestation
0.709 0.291 0.000
I00-I02 Acute rheumatic fever
0.708 0.292 0.000
O36.5 Maternal care for poor foetal growth
0.708 0.292 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.708 0.292 0.000
M42 Spinal osteochondrosis
0.706 0.294 0.000
M40 Kyphosis and lordosis
0.706 0.294 0.000
H10-H13 Disorders of conjunctiva
0.706 0.294 0.000
D23.0 Skin of lip
0.704 0.296 0.000
M48.9 Spondylopathy, unspecified
0.704 0.296 0.000
M48.8 Other specified spondylopathies
0.704 0.296 0.000
M48.4 Fatigue fracture of vertebra
0.704 0.296 0.000
M48.3 Traumatic spondylopathy
0.704 0.296 0.000
M48.2 Kissing spine
0.704 0.296 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.704 0.296 0.000
M43.0 Spondylolysis
0.702 0.298 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.702 0.298 0.000
I85.0 Oesophageal varices with bleeding
0.702 0.298 0.000
T66-T78 Other and unspecified effects of external causes
0.701 0.299 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.701 0.299 0.000
Chapter XXII Codes for special purposes
0.700 0.300 0.000
F33 Recurrent depressive disorder
0.699 0.300 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.699 0.301 0.000
K09 Cysts of oral region, not elsewhere classified
0.698 0.302 0.000
C34.3 Lower lobe, bronchus or lung
0.698 0.302 0.000
K08.2 Atrophy of edentulous alveolar ridge
0.698 0.302 0.000
F80-F89 Disorders of psychological development
0.698 0.302 0.000
O40 Polyhydramnios
0.697 0.303 0.000
S20-S29 Injuries to the thorax
0.697 0.303 0.000
K03 Other diseases of hard tissues of teeth
0.696 0.304 0.000
I42.2 Other hypertrophic cardiomyopathy
0.695 0.305 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.695 0.305 0.000
I31 Other diseases of pericardium
0.695 0.305 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.695 0.305 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.694 0.306 0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)
0.694 0.306 0.000
M48.05 Spinal stenosis (Thoracolumbar region)
0.694 0.306 0.000
M48.04 Spinal stenosis (Thoracic region)
0.694 0.306 0.000
M48.03 Spinal stenosis (Cervicothoracic region)
0.694 0.306 0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)
0.694 0.306 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.692 0.307 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.692 0.307 0.000
Q35-Q37 Cleft lip and cleft palate
0.692 0.307 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.692 0.307 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.692 0.307 0.000
Q00-Q07 Congenital malformations of the nervous system
0.692 0.307 0.000
O36.9 Maternal care for foetal problem, unspecified
0.692 0.308 0.000
C43 Malignant melanoma of skin
0.692 0.308 0.000
M51.3 Other specified intervertebral disk degeneration
0.691 0.308 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.691 0.308 0.000
M51.4 Schmorl's nodes
0.691 0.308 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.691 0.309 0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)
0.691 0.309 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.691 0.309 0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)
0.691 0.309 0.000
M54.92 Dorsalgia, unspecified (Cervical region)
0.691 0.309 0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)
0.691 0.309 0.000
K75 Other inflammatory liver diseases
0.691 0.309 0.000
C50.6 Axillary tail of breast
0.690 0.309 0.000
Chapter VI Diseases of the nervous system
0.691 0.309 0.000
H35 Other retinal disorders
0.690 0.310 0.000
M54.50 Low back pain (Multiple sites in spine)
0.689 0.311 0.000
M53 Other dorsopathies, not elsewhere classified
0.688 0.311 0.000
F31.9 Bipolar affective disorder, unspecified
0.688 0.312 0.000
K12.1 Other forms of stomatitis
0.688 0.312 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.687 0.313 0.000
D09 Carcinoma in situ of other and unspecified sites
0.687 0.313 0.000
M43.9 Deforming dorsopathy, unspecified
0.686 0.314 0.000
M43.8 Other specified deforming dorsopathies
0.686 0.314 0.000
M43.6 Torticollis
0.686 0.314 0.000
M43.5 Other recurrent vertebral subluxation
0.686 0.314 0.000
M43.4 Other recurrent atlantoaxial subluxation
0.686 0.314 0.000
M43.3 Recurrent atlantoaxial subluxation with myelopathy
0.686 0.314 0.000
M43.2 Other fusion of spine
0.686 0.314 0.000
I52 Other heart disorders in diseases classified elsewhere
0.685 0.315 0.000
I48 Atrial fibrillation and flutter
0.685 0.315 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.685 0.315 0.000
I41 Myocarditis in diseases classified elsewhere
0.685 0.315 0.000
I40 Acute myocarditis
0.685 0.315 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.685 0.315 0.000
I37 Pulmonary valve disorders
0.685 0.315 0.000
I36 Nonrheumatic tricuspid valve disorders
0.685 0.315 0.000
I32 Pericarditis in diseases classified elsewhere
0.685 0.315 0.000
H57.1 Ocular pain
0.685 0.315 0.000
D25.9 Leiomyoma of uterus, unspecified
0.685 0.315 0.000
K04.9 Other and unspecified diseases of pulp and periapical tissues
0.684 0.316 0.000
K04.3 Abnormal hard tissue formation in pulp
0.684 0.316 0.000
K04.2 Pulp degeneration
0.684 0.316 0.000
K04.1 Necrosis of pulp
0.684 0.316 0.000
K04.0 Pulpitis
0.684 0.316 0.000
M54.55 Low back pain (Thoracolumbar region)
0.684 0.316 0.000
M54.54 Low back pain-Thoracic
0.684 0.316 0.000
M54.53 Low back pain-Cervicothoracic
0.684 0.316 0.000
M54.52 Low back pain-Cervical
0.684 0.316 0.000
M54.51 Low back pain-Occipit-atl-axl
0.684 0.316 0.000
I88 Nonspecific lymphadenitis
0.684 0.316 0.000
C92 Myeloid leukaemia
0.684 0.316 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.684 0.316 0.000
C95 Leukaemia of unspecified cell type
0.684 0.316 0.000
C94 Other leukaemias of specified cell type
0.684 0.316 0.000
C93 Monocytic leukaemia
0.684 0.316 0.000
C86 Other specified types of T/NK-cell lymphoma
0.684 0.316 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.684 0.316 0.000
C81 Hodgkin's disease
0.684 0.316 0.000
O74 Complications of anaesthesia during labour and delivery
0.684 0.316 0.000
O71 Other obstetric trauma
0.684 0.316 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.684 0.316 0.000
O60 Preterm delivery
0.684 0.316 0.000
K00 Disorders of tooth development and eruption
0.684 0.316 0.000
O30 Multiple gestation
0.684 0.316 0.000
H51 Other disorders of binocular movement
0.684 0.316 0.000
H49 Paralytic strabismus
0.684 0.316 0.000
K74 Fibrosis and cirrhosis of liver
0.683 0.316 0.000
K81 Cholecystitis
0.683 0.317 0.000
K86.3 Pseudocyst of pancreas
0.682 0.317 0.000
K76.8 Other specified diseases of liver
0.682 0.318 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.681 0.319 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.681 0.319 0.000
S52.0 Fracture of upper end of ulna
0.680 0.320 0.000
I87.1 Compression of vein
0.680 0.320 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.679 0.321 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.678 0.322 0.000
I34.0 Mitral (valve) insufficiency
0.678 0.322 0.000
F23 Acute and transient psychotic disorders
0.678 0.322 0.000
C34.1 Upper lobe, bronchus or lung
0.677 0.323 0.000
K65-K67 Diseases of peritoneum
0.676 0.324 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.675 0.324 0.000
F70-F79 Mental retardation
0.675 0.324 0.000
O61.0 Failed medical induction of labour
0.675 0.325 0.000
K50-K52 Noninfective enteritis and colitis
0.674 0.326 0.000
O32.9 Maternal care for malpresentation of foetus, unspecified
0.673 0.327 0.000
O32.6 Maternal care for compound presentation
0.673 0.327 0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more
0.673 0.327 0.000
O32.4 Maternal care for high head at term
0.673 0.327 0.000
O32.0 Maternal care for unstable lie
0.673 0.327 0.000
M80-M85 Disorders of bone density and structure
0.673 0.327 0.000
M06.9 Rheumatoid arthritis, unspecified
0.672 0.328 0.000
I60 Subarachnoid haemorrhage
0.672 0.328 0.000
K92.2 Gastro-intestinal haemorrhage, unspecified
0.672 0.328 0.000
O20 Haemorrhage in early pregnancy
0.672 0.328 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.671 0.328 0.000
D22.3 Melanocytic naevi of other and unspecified parts of face
0.671 0.329 0.000
S10-S19 Injuries to the neck
0.671 0.329 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.671 0.329 0.000
H31 Other disorders of choroid
0.671 0.329 0.000
H30 Chorioretinal inflammation
0.671 0.329 0.000
M43.19 Spondylolisthesis (Site unspecified)
0.671 0.329 0.000
M43.18 Spondylolisthesis (Sacral and sacrococcygeal region)
0.671 0.329 0.000
M43.15 Spondylolisthesis (Thoracolumbar region)
0.671 0.329 0.000
M43.14 Spondylolisthesis (Thoracic region)
0.671 0.329 0.000
M43.13 Spondylolisthesis (Cervicothoracic region)
0.671 0.329 0.000
M43.12 Spondylolisthesis (Cervical region)
0.671 0.329 0.000
M43.11 Spondylolisthesis (Occipito-atlanto-axial region)
0.671 0.329 0.000
M43.10 Spondylolisthesis (Multiple sites in spine)
0.671 0.329 0.000
Q63 Other congenital malformations of kidney
0.670 0.330 0.000
D05.7 Other carcinoma in situ of breast
0.670 0.330 0.000
D05.0 Lobular carcinoma in situ
0.670 0.330 0.000
H52.7 Disorder of refraction, unspecified
0.670 0.330 0.000
H52.6 Other disorders of refraction
0.670 0.330 0.000
H52.5 Disorders of accommodation
0.670 0.330 0.000
H52.4 Presbyopia
0.670 0.330 0.000
Q21.1 Atrial septal defect
0.670 0.330 0.000
K10 Other diseases of jaws
0.668 0.331 0.000
D23.3 Skin of other and unspecified parts of face
0.668 0.332 0.000
I38 Endocarditis, valve unspecified
0.668 0.332 0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy
0.667 0.333 0.000
O36.4 Maternal care for intra-uterine death
0.667 0.333 0.000
O36.3 Maternal care for signs of foetal hypoxia
0.667 0.333 0.000
O36.2 Maternal care for hydrops foetalis
0.667 0.333 0.000
O36.1 Maternal care for other isoimmunisation
0.667 0.333 0.000
I69 Sequelae of cerebrovascular disease
0.665 0.335 0.000
O73 Retained placenta and membranes, without haemorrhage
0.664 0.336 0.000
D11 Benign neoplasm of major salivary glands
0.664 0.336 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.664 0.336 0.000
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge
0.664 0.336 0.000
I46.9 Cardiac arrest, unspecified
0.663 0.337 0.000
H33.4 Traction detachment of retina
0.662 0.337 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.662 0.338 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.662 0.338 0.000
O00-O08 Pregnancy with abortive outcome
0.662 0.338 0.000
K77 Liver disorders in diseases classified elsewhere
0.661 0.339 0.000
K73 Chronic hepatitis, not elsewhere classified
0.661 0.339 0.000
K71 Toxic liver disease
0.661 0.339 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.661 0.339 0.000
D23.9 Skin, unspecified
0.661 0.339 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.661 0.339 0.000
C91 Lymphoid leukaemia
0.660 0.340 0.000
M47.9 Spondylosis, unspecified
0.659 0.341 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.659 0.341 0.000
I95 Hypotension
0.659 0.341 0.000
M47.22 Other spondylosis with radiculopathy (Cervical region)
0.659 0.341 0.000
M54.16 Radiculopathy (Lumbar region)
0.658 0.342 0.000
D04.9 Skin, unspecified
0.658 0.342 0.000
D04.8 Skin of other sites
0.658 0.342 0.000
D04.5 Skin of trunk
0.658 0.342 0.000
D04.4 Skin of scalp and neck
0.658 0.342 0.000
D04.2 Skin of ear and external auricular canal
0.658 0.342 0.000
D04.1 Skin of eyelid, including canthus
0.658 0.342 0.000
D04.0 Skin of lip
0.658 0.342 0.000
T33-T35 Frostbite
0.658 0.342 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.658 0.342 0.000
T00-T07 Injuries involving multiple body regions
0.658 0.342 0.000
O80-O84 Delivery
0.658 0.342 0.000
I86 Varicose veins of other sites
0.657 0.343 0.000
M47.1 Other spondylosis with myelopathy
0.655 0.345 0.000
D21.1 Connective and other soft tissue of upper limb, including shoulder
0.653 0.347 0.000
C75 Malignant neoplasm of other endocrine glands and related structures
0.652 0.348 0.000
C74 Malignant neoplasm of adrenal gland
0.652 0.348 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.651 0.349 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.651 0.349 0.000
D03.7 Melanoma in situ of lower limb, including hip
0.651 0.349 0.000
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)
0.650 0.349 0.000
D26.1 Corpus uteri
0.650 0.350 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.650 0.350 0.000
I61.8 Other intracerebral haemorrhage
0.650 0.350 0.000
D22.4 Melanocytic naevi of scalp and neck
0.649 0.351 0.000
I47.1 Supraventricular tachycardia
0.649 0.351 0.000
M62 Other disorders of muscle
0.649 0.351 0.000
I05-I09 Chronic rheumatic heart diseases
0.648 0.352 0.000
F30.9 Manic episode, unspecified
0.648 0.352 0.000
C01 Malignant neoplasm of base of tongue
0.648 0.352 0.000
S51 Open wound of forearm
0.647 0.353 0.000
I47.0 Reentry ventricular arrhythmia
0.647 0.353 0.000
I44.7 Left bundle-branch block, unspecified
0.647 0.353 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.646 0.354 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.644 0.356 0.000
K72 Hepatic failure, not elsewhere classified
0.644 0.356 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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