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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs11755527
log Bayes Factor = 16.2085
Chromosome 6   position 90,958,231  (GRCh37) Explore rs11755527 on Ensembl!
Variant rs11755527 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
C44.6 Skin of upper limb, including shoulder
0.000 0.001 0.999
C44 Other malignant neoplasms of skin
0.000 0.002 0.998
C44.5 Skin of trunk
0.000 0.004 0.996
E03 Other hypothyroidism
0.991 0.009 0.000
E10-E14 Diabetes mellitus
0.985 0.015 0.000
E00-E07 Disorders of thyroid gland
0.985 0.015 0.000
E10 Insulin-dependent diabetes mellitus
0.984 0.016 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.976 0.024 0.000
E10.3 With ophthalmic complications
0.965 0.035 0.000
E10.9 Without complications
0.949 0.051 0.000
E06 Thyroiditis
0.949 0.051 0.000
E11 Non-insulin-dependent diabetes mellitus
0.937 0.063 0.000
E06.3 Autoimmune thyroiditis
0.926 0.074 0.000
C44.7 Skin of lower limb, including hip
0.000 0.075 0.925
C44.2 Skin of ear and external auricular canal
0.000 0.080 0.920
E10.4 With neurological complications
0.917 0.083 0.000
C44.1 Skin of eyelid, including canthus
0.000 0.086 0.914
E11.6 With other specified complications
0.885 0.115 0.000
E14 Unspecified diabetes mellitus
0.847 0.153 0.000
E13 Other specified diabetes mellitus
0.840 0.160 0.000
E11.4 With neurological complications
0.826 0.174 0.000
E03.1 Congenital hypothyroidism without goitre
0.821 0.179 0.000
E11.0 With coma
0.821 0.179 0.000
E10.1 With ketoacidosis
0.812 0.188 0.000
E11.3 With ophthalmic complications
0.793 0.207 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.778 0.222 0.000
C44.4 Skin of scalp and neck
0.000 0.223 0.777
E05 Thyrotoxicosis [hyperthyroidism]
0.770 0.230 0.000
E14.8 With unspecified complications
0.755 0.245 0.000
E50-E64 Other nutritional deficiencies
0.752 0.248 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.745 0.255 0.000
E06.5 Other chronic thyroiditis
0.741 0.259 0.000
C44.0 Skin of lip
0.000 0.264 0.736
E14.3 With ophthalmic complications
0.734 0.266 0.000
E13.3 With ophthalmic complications
0.731 0.269 0.000
E11.7 With multiple complications
0.727 0.273 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.721 0.279 0.000
C44.8 Overlapping lesion of skin
0.000 0.284 0.716
E03.5 Myxoedema coma
0.710 0.290 0.000
E03.4 Atrophy of thyroid (acquired)
0.710 0.290 0.000
E03.3 Postinfectious hypothyroidism
0.710 0.290 0.000
E10.2 With renal complications
0.709 0.291 0.000
E12 Malnutrition-related diabetes mellitus
0.706 0.294 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.706 0.294 0.000
E00 Congenital iodine-deficiency syndrome
0.706 0.294 0.000
E06.1 Subacute thyroiditis
0.687 0.313 0.000
E10.7 With multiple complications
0.683 0.316 0.000
E14.2 Withrenal complications
0.681 0.319 0.000
E06.4 Drug-induced thyroiditis
0.680 0.320 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.680 0.320 0.000
E06.0 Acute thyroiditis
0.680 0.320 0.000
E10.6 With other specified complications
0.675 0.325 0.000
C44.9 Malignant neoplasm of skin, unspecified
0.000 0.327 0.673
E11.1 With ketoacidosis
0.667 0.333 0.000
E14.6 With other specified complications
0.665 0.335 0.000
E05.9 Thyrotoxicosis, unspecified
0.659 0.341 0.000
J45.9 Asthma, unspecified
0.000 0.343 0.657
C67.9 Bladder, unspecified
0.656 0.344 0.000
C67 Malignant neoplasm of bladder
0.651 0.349 0.000
E40-E46 Malnutrition
0.649 0.351 0.000
E10.5 With peripheral circulatory complications
0.644 0.355 0.000
E16 Other disorders of pancreatic internal secretion
0.636 0.364 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.634 0.366 0.000
E03.8 Other specified hypothyroidism
0.626 0.374 0.000
E14.1 With ketoacidosis
0.620 0.380 0.000
E10.8 With unspecified complications
0.618 0.382 0.000
E10.0 With coma
0.615 0.385 0.000
E13.9 Without complications
0.613 0.387 0.000
E14.0 With coma
0.612 0.388 0.000
C67.6 Ureteric orifice
0.608 0.392 0.000
E14.7 With multiple complications
0.607 0.393 0.000
E11.8 With unspecified complications
0.604 0.395 0.000
E13.8 With unspecified complications
0.602 0.397 0.000
E13.7 With multiple complications
0.602 0.397 0.000
E13.6 With other specified complications
0.602 0.397 0.000
E13.5 With peripheral circulatory complications
0.602 0.397 0.000
E13.4 With neurological complications
0.602 0.397 0.000
E13.2 With renal complications
0.602 0.397 0.000
E13.1 With ketoacidosis
0.602 0.397 0.000
E13.0 With coma
0.602 0.397 0.000
E14.4 With neurological complications
0.601 0.399 0.000
E63 Other nutritional deficiencies
0.590 0.410 0.000
E58 Dietary calcium deficiency
0.586 0.414 0.000
E53 Deficiency of other B group vitamins
0.585 0.415 0.000
E11.5 With peripheral circulatory complications
0.583 0.417 0.000
C67.5 Bladder neck
0.578 0.422 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.565 0.435 0.000
E54 Ascorbic acid deficiency
0.564 0.436 0.000
E16.2 Hypoglycaemia, unspecified
0.562 0.438 0.000
E15 Nondiabetic hypoglycaemic coma
0.558 0.442 0.000
C67.3 Anterior wall of bladder
0.555 0.445 0.000
E06.9 Thyroiditis, unspecified
0.554 0.446 0.000
E05.5 Thyroid crisis or storm
0.552 0.448 0.000
E05.4 Thyrotoxicosis factitia
0.552 0.448 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.552 0.448 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.552 0.448 0.000
C67.4 Posterior wall of bladder
0.549 0.451 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.539 0.461 0.000
E50 Vitamin A deficiency
0.539 0.461 0.000
E60 Dietary zinc deficiency
0.539 0.461 0.000
E59 Dietary selenium deficiency
0.539 0.461 0.000
E52 Niacin deficiency [pellagra]
0.539 0.461 0.000
E51 Thiamine deficiency
0.530 0.470 0.000
E56 Other vitamin deficiencies
0.529 0.471 0.000
E05.8 Other thyrotoxicosis
0.526 0.474 0.000
C67.0 Trigone of bladder
0.523 0.477 0.000
E65-E68 Obesity and other hyperalimentation
0.520 0.480 0.000
E11.2 With renal complications
0.519 0.481 0.000
E14.5 With peripheral circulatory complications
0.519 0.481 0.000
E61 Deficiency of other nutrient elements
0.511 0.489 0.000
E12.9 Without complications
0.506 0.493 0.000
E12.8 With unspecified complications
0.506 0.493 0.000
E12.7 With multiple complications
0.506 0.493 0.000
E12.6 With other specified complications
0.506 0.493 0.000
E12.5 With peripheral circulatory complications
0.506 0.493 0.000
E12.4 With neurological complications
0.506 0.493 0.000
E12.3 With ophthalmic complications
0.506 0.493 0.000
E12.2 With renal complications
0.506 0.493 0.000
E12.1 With ketoacidosis
0.506 0.493 0.000
E12.0 With coma
0.506 0.493 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.506 0.494 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.506 0.494 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.506 0.494 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.506 0.494 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.506 0.494 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.506 0.494 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.506 0.494 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.506 0.494 0.000
C67.2 Lateral wall of bladder
0.503 0.497 0.000
E07 Other disorders of thyroid
0.489 0.510 0.000
C67.8 Overlapping lesion of bladder
0.486 0.514 0.000
E53.9 Vitamin B deficiency, unspecified
0.478 0.522 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.476 0.524 0.000
E63.9 Nutritional deficiency, unspecified
0.473 0.526 0.000
C67.1 Dome of bladder
0.469 0.531 0.000
C67.7 Urachus
0.467 0.533 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.465 0.534 0.000
E45 Retarded development following protein-energy malnutrition
0.465 0.534 0.000
E43 Unspecified severe protein-energy malnutrition
0.465 0.534 0.000
E42 Marasmic kwashiorkor
0.465 0.534 0.000
E41 Nutritional marasmus
0.465 0.534 0.000
E40 Kwashiorkor
0.465 0.534 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.456 0.544 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.456 0.544 0.000
E16.4 Abnormal secretion of gastrin
0.456 0.544 0.000
E16.3 Increased secretion of glucagon
0.456 0.544 0.000
E55 Vitamin D deficiency
0.436 0.564 0.000
E63.8 Other specified nutritional deficiencies
0.423 0.577 0.000
E63.1 Imbalance of constituents of food intake
0.423 0.577 0.000
E63.0 Essential fatty acid [EFA] deficiency
0.423 0.577 0.000
E53.1 Pyridoxine deficiency
0.420 0.580 0.000
E53.0 Riboflavin deficiency
0.420 0.580 0.000
E65 Localised adiposity
0.416 0.584 0.000
E46 Unspecified protein-energy malnutrition
0.415 0.585 0.000
C44.3 Skin of other and unspecified parts of face
0.000 0.587 0.413
E53.8 Deficiency of other specified B group vitamins
0.401 0.599 0.000
E50.9 Vitamin A deficiency, unspecified
0.387 0.613 0.000
E50.8 Other manifestations of vitamin A deficiency
0.387 0.613 0.000
E50.7 Other ocular manifestations of vitamin A deficiency
0.387 0.613 0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.387 0.613 0.000
E50.5 Vitamin A deficiency with night blindness
0.387 0.613 0.000
E50.4 Vitamin A deficiency with keratomalacia
0.387 0.613 0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.387 0.613 0.000
E50.2 Vitamin A deficiency with corneal xerosis
0.387 0.613 0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.387 0.613 0.000
E50.0 Vitamin A deficiency with conjunctival xerosis
0.387 0.613 0.000
E64.9 Sequelae of unspecified nutritional deficiency
0.387 0.613 0.000
E64.8 Sequelae of other nutritional deficiencies
0.387 0.613 0.000
E64.3 Sequelae of rickets
0.387 0.613 0.000
E64.2 Sequelae of vitamin C deficiency
0.387 0.613 0.000
E64.1 Sequelae of vitamin A deficiency
0.387 0.613 0.000
E64.0 Sequelae of protein-energy malnutrition
0.387 0.613 0.000
E51.9 Thiamine deficiency, unspecified
0.380 0.620 0.000
E51.8 Other manifestations of thiamine deficiency
0.380 0.620 0.000
E51.1 Beriberi
0.380 0.620 0.000
E56.9 Vitamin deficiency, unspecified
0.379 0.620 0.000
E56.8 Deficiency of other vitamins
0.379 0.620 0.000
E56.0 Deficiency of vitamin E
0.379 0.620 0.000
E61.2 Magnesium deficiency
0.376 0.624 0.000
E67 Other hyperalimentation
0.373 0.627 0.000
E68 Sequelae of hyperalimentation
0.373 0.627 0.000
E51.2 Wernicke's encephalopathy
0.371 0.629 0.000
E56.1 Deficiency of vitamin K
0.369 0.630 0.000
E61.9 Deficiency of nutrient element, unspecified
0.366 0.634 0.000
E61.8 Deficiency of other specified nutrient elements
0.366 0.634 0.000
E61.7 Deficiency of multiple nutrient elements
0.366 0.634 0.000
E61.6 Vanadium deficiency
0.366 0.634 0.000
E61.5 Molybdenum deficiency
0.366 0.634 0.000
E61.4 Chromium deficiency
0.366 0.634 0.000
E61.3 Manganese deficiency
0.366 0.634 0.000
E61.0 Copper deficiency
0.366 0.634 0.000
E16.1 Other hypoglycaemia
0.360 0.640 0.000
E07.1 Dyshormogenetic goitre
0.351 0.649 0.000
E07.0 Hypersecretion of calcitonin
0.351 0.649 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.340 0.660 0.000
E44.1 Mild protein-energy malnutrition
0.334 0.666 0.000
E44.0 Moderate protein-energy malnutrition
0.334 0.666 0.000
E61.1 Iron deficiency
0.325 0.675 0.000
E55.0 Rickets, active
0.313 0.687 0.000
C64-C68 Malignant neoplasms of urinary tract
0.306 0.694 0.000
E07.8 Other specified disorders of thyroid
0.301 0.699 0.000
E67.8 Other specified hyperalimentation
0.267 0.732 0.000
E67.3 Hypervitaminosis D
0.267 0.732 0.000
E67.2 Megavitamin-B6 syndrome
0.267 0.732 0.000
E67.1 Hypercarotenaemia
0.267 0.732 0.000
E67.0 Hypervitaminosis A
0.267 0.732 0.000
C65 Malignant neoplasm of renal pelvis
0.242 0.757 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.238 0.762 0.000
E07.9 Disorder of thyroid, unspecified
0.229 0.771 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.225 0.775 0.000
E55.9 Vitamin D deficiency, unspecified
0.210 0.790 0.000
J45 Asthma
0.000 0.796 0.204
C68.9 Urinary organ, unspecified
0.185 0.814 0.000
J33.0 Polyp of nasal cavity
0.000 0.815 0.185
C66 Malignant neoplasm of ureter
0.180 0.820 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.000 0.823 0.177
C68.0 Urethra
0.174 0.826 0.000
J33 Nasal polyp
0.000 0.829 0.171
C68.8 Overlapping lesion of urinary organs
0.170 0.829 0.000
C68.1 Paraurethral glands
0.170 0.829 0.000
J33.9 Nasal polyp, unspecified
0.000 0.830 0.170
J45.8 Mixed asthma
0.000 0.850 0.150
J45.1 Nonallergic asthma
0.000 0.857 0.142
J33.8 Other polyp of sinus
0.000 0.865 0.135
E04 Other non-toxic goitre
0.115 0.885 0.000
J33.1 Polypoid sinus degeneration
0.000 0.886 0.114
E20-E35 Disorders of other endocrine glands
0.102 0.898 0.000
E11.9 Without complications
0.085 0.915 0.000
E04.8 Other specified non-toxic goitre
0.082 0.917 0.000
E34 Other endocrine disorders
0.081 0.919 0.000
E27 Other disorders of adrenal gland
0.080 0.920 0.000
E04.9 Non-toxic goitre, unspecified
0.077 0.923 0.000
E22 Hyperfunction of pituitary gland
0.077 0.923 0.000
E27.1 Primary adrenocortical insufficiency
0.076 0.924 0.000
O48 Prolonged pregnancy
0.000 0.926 0.074
E25 Adrenogenital disorders
0.074 0.926 0.000
E31 Polyglandular dysfunction
0.073 0.926 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.073 0.927 0.000
E32 Diseases of thymus
0.073 0.927 0.000
E30 Disorders of puberty, not elsewhere classified
0.073 0.927 0.000
J45.0 Predominantly allergic asthma
0.000 0.929 0.071
E26 Hyperaldosteronism
0.067 0.933 0.000
E27.2 Addisonian crisis
0.066 0.934 0.000
E34.8 Other specified endocrine disorders
0.064 0.935 0.000
J40-J47 Chronic lower respiratory diseases
0.000 0.936 0.064
E34.9 Endocrine disorder, unspecified
0.064 0.936 0.000
E22.0 Acromegaly and pituitary gigantism
0.062 0.938 0.000
E04.0 Non-toxic diffuse goitre
0.061 0.939 0.000
E20 Hypoparathyroidism
0.061 0.939 0.000
E66 Obesity
0.061 0.939 0.000
E34.3 Short stature, not elsewhere classified
0.059 0.941 0.000
E34.5 Androgen resistance syndrome
0.058 0.942 0.000
E34.4 Constitutional tall stature
0.058 0.942 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.058 0.942 0.000
E34.1 Other hypersecretion of intestinal hormones
0.058 0.942 0.000
E27.5 Adrenomedullary hyperfunction
0.058 0.942 0.000
E27.0 Other adrenocortical overactivity
0.058 0.942 0.000
E14.9 Without complications
0.057 0.943 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.057 0.943 0.000
J42 Unspecified chronic bronchitis
0.000 0.943 0.057
E29 Testicular dysfunction
0.056 0.944 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.055 0.945 0.000
E22.8 Other hyperfunction of pituitary gland
0.055 0.945 0.000
E22.1 Hyperprolactinaemia
0.054 0.946 0.000
E34.0 Carcinoid syndrome
0.054 0.946 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.054 0.946 0.000
E31.0 Autoimmune polyglandular failure
0.053 0.947 0.000
E25.9 Adrenogenital disorder, unspecified
0.053 0.947 0.000
E25.8 Other adrenogenital disorders
0.053 0.947 0.000
E31.9 Polyglandular dysfunction, unspecified
0.053 0.947 0.000
E31.8 Other polyglandular dysfunction
0.053 0.947 0.000
E31.1 Polyglandular hyperfunction
0.053 0.947 0.000
E30.9 Disorder of puberty, unspecified
0.052 0.947 0.000
E30.8 Other disorders of puberty
0.052 0.947 0.000
E30.1 Precocious puberty
0.052 0.947 0.000
E30.0 Delayed puberty
0.052 0.947 0.000
E32.9 Disease of thymus, unspecified
0.052 0.947 0.000
E32.8 Other diseases of thymus
0.052 0.947 0.000
E32.1 Abscess of thymus
0.052 0.947 0.000
E32.0 Persistent hyperplasia of thymus
0.052 0.947 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.052 0.947 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.052 0.947 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.052 0.947 0.000
E27.9 Disorder of adrenal gland, unspecified
0.052 0.947 0.000
J46 Status asthmaticus
0.000 0.948 0.052
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.052 0.948 0.000
J41 Simple and mucopurulent chronic bronchitis
0.000 0.948 0.052
E26.9 Hyperaldosteronism, unspecified
0.050 0.949 0.000
E24 Cushing's syndrome
0.049 0.950 0.000
E28 Ovarian dysfunction
0.049 0.951 0.000
J43 Emphysema
0.000 0.951 0.049
E26.8 Other hyperaldosteronism
0.048 0.952 0.000
E26.1 Secondary hyperaldosteronism
0.048 0.952 0.000
J47 Bronchiectasis
0.000 0.952 0.048
J43.9 Emphysema, unspecified
0.000 0.955 0.045
E20.8 Other hypoparathyroidism
0.044 0.956 0.000
E20.1 Pseudohypoparathyroidism
0.044 0.956 0.000
E20.0 Idiopathic hypoparathyroidism
0.044 0.956 0.000
E66.1 Drug-induced obesity
0.044 0.956 0.000
J41.0 Simple chronic bronchitis
0.000 0.957 0.043
E66.2 Extreme obesity with alveolar hypoventilation
0.042 0.958 0.000
E29.9 Testicular dysfunction, unspecified
0.040 0.959 0.000
E29.8 Other testicular dysfunction
0.040 0.959 0.000
E29.0 Testicular hyperfunction
0.040 0.959 0.000
E27.8 Other specified disorders of adrenal gland
0.040 0.960 0.000
L57.0 Actinic keratosis
0.000 0.962 0.038
E26.0 Primary hyperaldosteronism
0.038 0.962 0.000
E24.2 Drug-induced Cushing's syndrome
0.038 0.962 0.000
J41.8 Mixed simple and mucopurulent chronic bronchitis
0.000 0.962 0.037
J41.1 Mucopurulent chronic bronchitis
0.000 0.962 0.037
E27.4 Other and unspecified adrenocortical insufficiency
0.036 0.964 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.035 0.964 0.000
E24.3 Ectopic ACTH syndrome
0.035 0.964 0.000
E24.1 Nelson's syndrome
0.035 0.964 0.000
E28.9 Ovarian dysfunction, unspecified
0.036 0.964 0.000
E28.8 Other ovarian dysfunction
0.036 0.964 0.000
E28.1 Androgen excess
0.036 0.964 0.000
E28.0 Oestrogen excess
0.036 0.964 0.000
J43.1 Panlobular emphysema
0.000 0.965 0.035
J43.0 MacLeod's syndrome
0.000 0.965 0.035
E23 Hypofunction and other disorders of pituitary gland
0.035 0.965 0.000
J43.8 Other emphysema
0.000 0.966 0.034
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.034 0.966 0.000
E66.0 Obesity due to excess calories
0.033 0.966 0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods
0.033 0.967 0.000
E24.8 Other Cushing's syndrome
0.033 0.967 0.000
E20.9 Hypoparathyroidism, unspecified
0.031 0.968 0.000
E28.3 Primary ovarian failure
0.030 0.970 0.000
E24.9 Cushing's syndrome, unspecified
0.029 0.971 0.000
E23.7 Disorder of pituitary gland, unspecified
0.026 0.974 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.025 0.975 0.000
E23.1 Drug-induced hypopituitarism
0.025 0.975 0.000
E24.0 Pituitary-dependent Cushing's disease
0.024 0.975 0.001
E29.1 Testicular hypofunction
0.024 0.976 0.000
H18.4 Corneal degeneration
0.024 0.976 0.000
E21.4 Other specified disorders of parathyroid gland
0.024 0.976 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.024 0.976 0.000
E23.2 Diabetes insipidus
0.024 0.976 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.023 0.977 0.000
E21.2 Other hyperparathyroidism
0.023 0.977 0.000
E28.2 Polycystic ovarian syndrome
0.023 0.977 0.000
Z85.5 Personal history of malignant neoplasm of urinary tract
0.022 0.978 0.000
H18 Other disorders of cornea
0.022 0.978 0.000
Z03.5 Observation for other suspected cardiovascular diseases
0.021 0.979 0.000
H18.1 Bullous keratopathy
0.020 0.980 0.000
J43.2 Centrilobular emphysema
0.000 0.980 0.019
H18.5 Hereditary corneal dystrophies
0.019 0.981 0.000
O63.1 Prolonged second stage (of labour)
0.000 0.981 0.019
I60.9 Subarachnoid haemorrhage, unspecified
0.019 0.981 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.981 0.019
H18.9 Disorder of cornea, unspecified
0.018 0.982 0.000
E23.6 Other disorders of pituitary gland
0.018 0.982 0.000
E21.0 Primary hyperparathyroidism
0.018 0.982 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.000 0.983 0.017
H18.2 Other corneal oedema
0.016 0.983 0.000
H18.0 Corneal pigmentations and deposits
0.016 0.984 0.000
H18.7 Other corneal deformities
0.016 0.984 0.000
H18.8 Other specified disorders of cornea
0.015 0.984 0.000
E21.3 Hyperparathyroidism, unspecified
0.015 0.985 0.000
H18.6 Keratoconus
0.015 0.985 0.000
H18.3 Changes in corneal membranes
0.015 0.985 0.000
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.985 0.015
L57.4 Cutis laxa senilis
0.000 0.986 0.014
E04.2 Non-toxic multinodular goitre
0.014 0.986 0.000
L57.5 Actinic granuloma
0.000 0.986 0.014
L57.3 Poikiloderma of Civatte
0.000 0.986 0.014
L57.2 Cutis rhomboidalis nuchae
0.000 0.986 0.014
L57.1 Actinic reticuloid
0.000 0.986 0.014
I60 Subarachnoid haemorrhage
0.014 0.986 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.013 0.987 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.013 0.987 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.012 0.988 0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.012 0.988 0.000
J44 Other chronic obstructive pulmonary disease
0.000 0.989 0.011
E04.1 Non-toxic single thyroid nodule
0.010 0.989 0.001
E70-E90 Metabolic disorders
0.011 0.989 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.000 0.989 0.011
C43 Malignant melanoma of skin
0.000 0.989 0.011
I60.4 Subarachnoid haemorrhage from basilar artery
0.011 0.989 0.000
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.990 0.010
I60.5 Subarachnoid haemorrhage from vertebral artery
0.010 0.990 0.000
R41.0 Disorientation, unspecified
0.010 0.990 0.000
O63 Long labour
0.000 0.990 0.010
I60.8 Other subarachnoid haemorrhage
0.009 0.991 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.009 0.991 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.991 0.009
C43.6 Malignant melanoma of upper limb, including shoulder
0.000 0.991 0.009
S42.20 Fracture of upper end of humerus (closed)
0.000 0.991 0.009
T78.2 Anaphylactic shock, unspecified
0.000 0.991 0.009
E23.0 Hypopituitarism
0.008 0.992 0.000
E74 Other disorders of carbohydrate metabolism
0.008 0.992 0.000
E88 Other metabolic disorders
0.008 0.992 0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.008 0.992 0.000
Z36.0 Antenatal screening for chromosomal anomalies
0.008 0.992 0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.008 0.992 0.000
Z53.9 Procedure not carried out, unspecified reason
0.000 0.992 0.008
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.008 0.992 0.000
E77 Disorders of glycoprotein metabolism
0.008 0.992 0.000
E76 Disorders of glycosaminoglycan metabolism
0.008 0.992 0.000
E72 Other disorders of amino-acid metabolism
0.008 0.992 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.008 0.992 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.008 0.992 0.000
C43.8 Overlapping malignant melanoma of skin
0.000 0.992 0.008
C43.0 Malignant melanoma of lip
0.000 0.992 0.008
E70 Disorders of aromatic amino-acid metabolism
0.008 0.992 0.000
E88.1 Lipodystrophy, not elsewhere classified
0.008 0.992 0.000
C43.1 Malignant melanoma of eyelid, including canthus
0.000 0.992 0.007
O63.9 Long labour, unspecified
0.000 0.992 0.008
E80 Disorders of porphyrin and bilirubin metabolism
0.008 0.992 0.000
E84 Cystic fibrosis
0.007 0.993 0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.007 0.993 0.000
O63.2 Delayed delivery of second twin, triplet, etc.
0.000 0.993 0.007
D51 Vitamin B12 deficiency anaemia
0.007 0.993 0.000
C43.9 Malignant melanoma of skin, unspecified
0.000 0.993 0.007
C43.2 Malignant melanoma of ear and external auricular canal
0.000 0.993 0.007
E85 Amyloidosis
0.007 0.993 0.000
Z36 Antenatal screening
0.007 0.993 0.000
E79 Disorders of purine and pyrimidine metabolism
0.007 0.993 0.000
E73 Lactose intolerance
0.007 0.993 0.000
J40 Bronchitis, not specified as acute or chronic
0.000 0.993 0.007
D51.8 Other vitamin B12 deficiency anaemias
0.006 0.993 0.000
E74.0 Glycogen storage disease
0.006 0.993 0.000
E88.9 Metabolic disorder, unspecified
0.006 0.993 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.994 0.006
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.006 0.994 0.000
E75.2 Other sphingolipidosis
0.006 0.994 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.000 0.994 0.006
E88.3 Tumour lysis syndrome
0.006 0.994 0.000
E74.3 Other disorders of intestinal carbohydrate absorption
0.006 0.994 0.000
E74.9 Disorder of carbohydrate metabolism, unspecified
0.006 0.994 0.000
E74.8 Other specified disorders of carbohydrate metabolism
0.006 0.994 0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.006 0.994 0.000
E74.2 Disorders of galactose metabolism
0.006 0.994 0.000
E74.1 Disorders of fructose metabolism
0.006 0.994 0.000
D61.9 Aplastic anaemia, unspecified
0.006 0.994 0.000
E80.1 Porphyria cutanea tarda
0.006 0.994 0.000
E75.6 Lipid storage disorder, unspecified
0.006 0.994 0.000
E75.4 Neuronal ceroid lipofuscinosis
0.006 0.994 0.000
E75.3 Sphingolipidosis, unspecified
0.006 0.994 0.000
E75.1 Other gangliosidosis
0.006 0.994 0.000
E75.0 GM2 gangliosidosis
0.006 0.994 0.000
E71.3 Disorders of fatty-acid metabolism
0.006 0.994 0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.006 0.994 0.000
E71.1 Other disorders of branched-chain amino-acid metabolism
0.006 0.994 0.000
E71.0 Maple-syrup-urine disease
0.006 0.994 0.000
E72.9 Disorder of amino-acid metabolism, unspecified
0.006 0.994 0.000
E72.8 Other specified disorders of amino-acid metabolism
0.006 0.994 0.000
E72.5 Disorders of glycine metabolism
0.006 0.994 0.000
E72.4 Disorders of ornithine metabolism
0.006 0.994 0.000
E72.3 Disorders of lysine and hydroxylysine metabolism
0.006 0.994 0.000
E72.2 Disorders of urea cycle metabolism
0.006 0.994 0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.006 0.994 0.000
E72.0 Disorders of amino-acid transport
0.006 0.994 0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.006 0.994 0.000
E76.8 Other disorders of glucosaminoglycan metabolism
0.006 0.994 0.000
E76.3 Mucopolysaccharidosis, unspecified
0.006 0.994 0.000
E76.2 Other mucopolysaccharidoses
0.006 0.994 0.000
E76.1 Mucopolysaccharidosis, type II
0.006 0.994 0.000
E76.0 Mucopolysaccharidosis, type I
0.006 0.994 0.000
E77.9 Disorder of glycoprotein metabolism, unspecified
0.006 0.994 0.000
E77.8 Other disorders of glycoprotein metabolism
0.006 0.994 0.000
E77.1 Defects in glycoprotein degradation
0.006 0.994 0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.006 0.994 0.000
E75.5 Other lipid storage disorders
0.006 0.994 0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis
0.006 0.994 0.000
E88.2 Lipomatosis, not elsewhere classified
0.006 0.994 0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.006 0.994 0.000
E70.8 Other disorders of aromatic amino-acid metabolism
0.006 0.994 0.000
E70.2 Disorders of tyrosine metabolism
0.006 0.994 0.000
E70.1 Other hyperphenylalaninaemias
0.006 0.994 0.000
E70.0 Classical phenylketonuria
0.006 0.994 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.994 0.006
S81.8 Open wound of other parts of lower leg
0.006 0.994 0.000
C43.4 Malignant melanoma of scalp and neck
0.000 0.994 0.006
E70.3 Albinism
0.005 0.994 0.000
E80.7 Disorder of bilirubin metabolism, unspecified
0.006 0.994 0.000
E80.5 Crigler-Najjar syndrome
0.006 0.994 0.000
E80.3 Defects of catalase and peroxydase
0.006 0.994 0.000
E80.0 Hereditary erythropoietic porphyria
0.006 0.994 0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress
0.000 0.994 0.006
E84.8 Cystic fibrosis with other manifestations
0.005 0.994 0.000
E84.1 Cystic fibrosis with intestinal manifestations
0.005 0.994 0.000
E84.0 Cystic fibrosis with pulmonary manifestations
0.005 0.994 0.000
E83 Disorders of mineral metabolism
0.006 0.994 0.000
E88.8 Other specified metabolic disorders
0.005 0.994 0.000
E80.6 Other disorders of bilirubin metabolism
0.005 0.994 0.000
D51.2 Transcobalamin II deficiency
0.005 0.994 0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.005 0.994 0.000
E83.4 Disorders of magnesium metabolism
0.006 0.994 0.000
M54.4 Lumbago with sciatica
0.005 0.995 0.000
E85.2 Heredofamilial amyloidosis, unspecified
0.005 0.995 0.000
E85.1 Neuropathic heredofamilial amyloidosis
0.005 0.995 0.000
E85.0 Nonneuropathic heredofamilial amyloidosis
0.005 0.995 0.000
J38.3 Other diseases of vocal cords
0.000 0.995 0.005
O63.0 Prolonged first stage (of labour)
0.000 0.995 0.005
E85.3 Secondary systemic amyloidosis
0.005 0.995 0.000
O73 Retained placenta and membranes, without haemorrhage
0.000 0.995 0.005
E85.8 Other amyloidosis
0.005 0.995 0.000
E85.4 Organ-limited amyloidosis
0.005 0.995 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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