TreeWAS – Variant ID: rs11758636

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
L40.9 Psoriasis, unspecified	1.000	0.000
C44 Other malignant neoplasms of skin	0.999	0.001
Chapter II Neoplasms	0.999	0.001
C43-C44 Melanoma and other malignant neoplasms of skin	0.999	0.001
L40 Psoriasis	0.997	0.003
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.993	0.007
L40-L45 Papulosquamous disorders	0.990	0.010
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.989	0.011
C15-C26 Malignant neoplasms of digestive organs	0.987	0.013
# Top node	0.986	0.014
Chapter XII Diseases of the skin and subcutaneous tissue	0.985	0.015
C78.7 Secondary malignant neoplasm of liver	0.985	0.015
Chapter V Mental and behavioural disorders	0.984	0.016
F30-F39 Mood [affective] disorders	0.983	0.017
C44.3 Skin of other and unspecified parts of face	0.979	0.021
Chapter VII Diseases of the eye and adnexa	0.979	0.021
D00-D09 In situ neoplasms	0.973	0.027
F31 Bipolar affective disorder	0.973	0.027
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.969	0.031
M45-M49 Spondylopathies	0.961	0.039
M47 Spondylosis	0.958	0.042
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.949	0.051
M47.8 Other spondylosis	0.948	0.052
H53-H54 Visual disturbances and blindness	0.946	0.054
C44.5 Skin of trunk	0.943	0.057
C19 Malignant neoplasm of rectosigmoid junction	0.942	0.058
C78.0 Secondary malignant neoplasm of lung	0.934	0.066
M47.82 Other spondylosis (Cervical region)	0.933	0.067
C44.1 Skin of eyelid, including canthus	0.931	0.069
C18 Malignant neoplasm of colon	0.927	0.073
C44.2 Skin of ear and external auricular canal	0.926	0.074
H54 Blindness and low vision	0.925	0.075
H30-H36 Disorders of choroid and retina	0.925	0.075
M50-M54 Other dorsopathies	0.924	0.076
F30 Manic episode	0.915	0.085
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.912	0.088
D05 Carcinoma in situ of breast	0.907	0.093
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.907	0.093
F31.9 Bipolar affective disorder, unspecified	0.905	0.095
L60-L75 Disorders of skin appendages	0.899	0.101
C44.4 Skin of scalp and neck	0.891	0.109
H35 Other retinal disorders	0.891	0.109
D03 Melanoma in situ	0.890	0.110
T36-T50 Poisoning by drugs, medicaments and biological substances	0.882	0.118
H35.3 Degeneration of macula and posterior pole	0.880	0.120
S90-S99 Injuries to the ankle and foot	0.873	0.127
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.872	0.128
T66-T78 Other and unspecified effects of external causes	0.868	0.132
L40.0 Psoriasis vulgaris	0.865	0.135
D05.1 Intraductal carcinoma in situ	0.860	0.140
F99-F99 Unspecified mental disorder	0.856	0.144
M47.9 Spondylosis, unspecified	0.856	0.144
C18.9 Colon, unspecified	0.855	0.145
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.852	0.148
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.851	0.149
H54.0 Blindness, both eyes	0.849	0.151
C71 Malignant neoplasm of brain	0.848	0.152
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.843	0.157
L40.5 Arthropathic psoriasis	0.826	0.174
D03.5 Melanoma in situ of trunk	0.822	0.178
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.818	0.182
L72 Follicular cysts of skin and subcutaneous tissue	0.815	0.185
F31.0 Bipolar affective disorder, current episode hypomanic	0.810	0.190
M47.89 Other spondylosis (Site unspecified)	0.810	0.190
F33 Recurrent depressive disorder	0.810	0.190
M50 Cervical disk disorders	0.809	0.191
T15-T19 Effects of foreign body entering through natural orifice	0.805	0.195
F39 Unspecified mood [affective] disorder	0.803	0.197
C15 Malignant neoplasm of oesophagus	0.803	0.197
M54 Dorsalgia	0.801	0.199
S92 Fracture of foot, except ankle	0.800	0.200
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.799	0.201
H54.9 Unspecified visual impairment (binocular)	0.798	0.202
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.797	0.202
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.797	0.203
F32 Depressive episode	0.796	0.204
C17 Malignant neoplasm of small intestine	0.793	0.207
C43 Malignant melanoma of skin	0.791	0.209
H46-H48 Disorders of optic nerve and visual pathways	0.791	0.209
H54.7 Unspecified visual loss	0.787	0.213
C18.6 Descending colon	0.786	0.214
C77.1 Intrathoracic lymph nodes	0.785	0.215
T78 Adverse effects, not elsewhere classified	0.784	0.216
H10-H13 Disorders of conjunctiva	0.782	0.218
F30.0 Hypomania	0.780	0.220
T92 Sequelae of injuries of upper limb	0.778	0.222
C78.4 Secondary malignant neoplasm of small intestine	0.778	0.222
M86-M90 Other osteopathies	0.776	0.224
M47.99 Spondylosis, unspecified (Site unspecified)	0.772	0.228
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.772	0.228
M51 Other intervertebral disk disorders	0.771	0.229
M00-M03 Infectious arthropathies	0.770	0.230
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.770	0.230
C44.0 Skin of lip	0.770	0.230
M47.2 Other spondylosis with radiculopathy	0.769	0.231
F80-F89 Disorders of psychological development	0.769	0.231
M91-M94 Chondropathies	0.768	0.232
F99 Mental disorder, not otherwise specified	0.765	0.235
D04 Carcinoma in situ of skin	0.763	0.237
C78.1 Secondary malignant neoplasm of mediastinum	0.762	0.238
M50.3 Other cervical disk degeneration	0.762	0.238
F30.9 Manic episode, unspecified	0.761	0.239
M47.80 Other spondylosis (Multiple sites in spine)	0.760	0.240
T20-T25 Burns and corrosions of external body surface, specified by site	0.758	0.242
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.757	0.243
H33 Retinal detachments and breaks	0.755	0.245
F30.2 Mania with psychotic symptoms	0.755	0.245
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.754	0.246
M60-M63 Disorders of muscles	0.754	0.246
F52 Sexual dysfunction, not caused by organic disorder or disease	0.752	0.248
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.752	0.248
T91 Sequelae of injuries of neck and trunk	0.751	0.249
C25 Malignant neoplasm of pancreas	0.751	0.249
C77.2 Intra-abdominal lymph nodes	0.747	0.253
C76 Malignant neoplasm of other and ill-defined sites	0.746	0.254
L70 Acne	0.746	0.254
M54.5 Low back pain	0.745	0.255
H35.4 Peripheral retinal degeneration	0.745	0.255
F31.6 Bipolar affective disorder, current episode mixed	0.745	0.255
M46 Other inflammatory spondylopathies	0.744	0.256
H18 Other disorders of cornea	0.744	0.256
L72.1 Trichilemmal cyst	0.742	0.258
C18.3 Hepatic flexure	0.741	0.259
T46 Poisoning by agents primarily affecting the cardiovascular system	0.740	0.260
M47.87 Other spondylosis (Lumbosacral region)	0.737	0.263
C18.8 Overlapping lesion of colon	0.735	0.264
C71.1 Frontal lobe	0.734	0.266
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.733	0.267
C44.9 Malignant neoplasm of skin, unspecified	0.733	0.267
C44.7 Skin of lower limb, including hip	0.733	0.267
S92.0 Fracture of calcaneus	0.731	0.269
S40-S49 Injuries to the shoulder and upper arm	0.730	0.270
H54.4 Blindness, one eye	0.724	0.276
L71 Rosacea	0.724	0.276
T43.0 Tricyclic and tetracyclic antidepressants	0.723	0.277
D02 Carcinoma in situ of middle ear and respiratory system	0.722	0.277
M54.1 Radiculopathy	0.720	0.280
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.720	0.280
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.719	0.281
C44.8 Overlapping lesion of skin	0.717	0.283
C40-C41 Malignant neoplasms of bone and articular cartilage	0.716	0.283
D03.6 Melanoma in situ of upper limb, including shoulder	0.715	0.285
L40.8 Other psoriasis	0.715	0.285
L40.4 Guttate psoriasis	0.715	0.285
L40.3 Pustulosis palmaris et plantaris	0.715	0.285
L40.2 Acrodermatitis continua	0.715	0.285
L40.1 Generalised pustular psoriasis	0.715	0.285
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified	0.713	0.287
T78.3 Angioneurotic oedema	0.712	0.288
C43.5 Malignant melanoma of trunk	0.711	0.289
L44 Other papulosquamous disorders	0.709	0.290
L41 Parapsoriasis	0.709	0.290
L45 Papulosquamous disorders in diseases classified elsewhere	0.709	0.290
L42 Pityriasis rosea	0.709	0.290
M54.56 Low back pain (Lumbar region)	0.709	0.291
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.709	0.291
H21 Other disorders of iris and ciliary body	0.709	0.291
M51.2 Other specified intervertebral disk displacement	0.709	0.291
C23 Malignant neoplasm of gallbladder	0.707	0.292
Chapter XVI Certain conditions originating in the perinatal period	0.707	0.293
L10-L14 Bullous disorders	0.706	0.293
L50-L54 Urticaria and erythema	0.706	0.294
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.705	0.295
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.705	0.295
F70-F79 Mental retardation	0.705	0.295
F38 Other mood [affective] disorders	0.705	0.295
F34 Persistent mood [affective] disorders	0.705	0.295
C77.9 Lymph node, unspecified	0.705	0.295
C77.3 Axillary and upper limb lymph nodes	0.703	0.297
C77.0 Lymph nodes of head, face and neck	0.702	0.298
C77.8 Lymph nodes of multiple regions	0.701	0.299
H35.5 Hereditary retinal dystrophy	0.701	0.299
F60-F69 Disorders of adult personality and behaviour	0.700	0.299
H17 Corneal scars and opacities	0.700	0.300
M47.97 Spondylosis, unspecified (Lumbosacral region)	0.699	0.301
L57 Skin changes due to chronic exposure to nonionising radiation	0.698	0.302
T68 Hypothermia	0.698	0.302
D01 Carcinoma in situ of other and unspecified digestive organs	0.698	0.302
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.698	0.302
M49 Spondylopathies in diseases classified elsewhere	0.697	0.303
F31.8 Other bipolar affective disorders	0.697	0.303
F31.7 Bipolar affective disorder, currently in remission	0.697	0.303
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.697	0.303
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.697	0.303
T00-T07 Injuries involving multiple body regions	0.696	0.304
C71.4 Occipital lobe	0.696	0.304
M40-M43 Deforming dorsopathies	0.695	0.305
T36 Poisoning by systemic antibiotics	0.691	0.308
Chapter XXII Codes for special purposes	0.691	0.309
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.691	0.309
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.690	0.310
M47.0 Anterior spinal and vertebral artery compression syndromes	0.687	0.313
C71.8 Overlapping lesion of brain	0.687	0.313
H47 Other disorders of optic [2nd] nerve and visual pathways	0.684	0.316
F32.3 Severe depressive episode with psychotic symptoms	0.683	0.317
M47.94 Spondylosis, unspecified (Thoracic region)	0.682	0.318
D09 Carcinoma in situ of other and unspecified sites	0.682	0.318
F52.2 Failure of genital response	0.681	0.319
S92.00 Fracture of calcaneus (closed)	0.681	0.319
T33-T35 Frostbite	0.681	0.319
T26-T28 Burns and corrosions confined to eye and internal organs	0.681	0.319
D05.9 Carcinoma in situ of breast, unspecified	0.680	0.320
M47.88 Other spondylosis (Sacral and sacrococcygeal region)	0.680	0.320
M47.85 Other spondylosis (Thoracolumbar region)	0.680	0.320
M47.84 Other spondylosis (Thoracic region)	0.680	0.320
M47.83 Other spondylosis (Cervicothoracic region)	0.680	0.320
M47.81 Other spondylosis (Occipito-atlanto-axial region)	0.680	0.320
F32.0 Mild depressive episode	0.678	0.322
S10-S19 Injuries to the neck	0.678	0.322
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.676	0.324
S99 Other and unspecified injuries of ankle and foot	0.675	0.325
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.675	0.325
M50.2 Other cervical disk displacement	0.674	0.326
H34 Retinal vascular occlusions	0.673	0.327
D06 Carcinoma in situ of cervix uteri	0.673	0.327
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.669	0.331
C26 Malignant neoplasm of other and ill-defined digestive organs	0.669	0.331
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.668	0.332
T91.2 Sequelae of other fracture of thorax and pelvis	0.667	0.333
S91 Open wound of ankle and foot	0.667	0.333
C18.1 Appendix	0.665	0.335
T17 Foreign body in respiratory tract	0.665	0.335
H31 Other disorders of choroid	0.664	0.336
C43.9 Malignant melanoma of skin, unspecified	0.663	0.337
H54.6 Unqualified visual loss, one eye	0.663	0.337
H54.5 Low vision, one eye	0.663	0.337
H54.3 Unqualified visual loss, both eyes	0.663	0.337
H54.2 Low vision, both eyes	0.663	0.337
H54.1 Blindness, one eye, low vision, other eye	0.663	0.337
H32 Chorioretinal disorders in diseases classified elsewhere	0.663	0.337
H30 Chorioretinal inflammation	0.663	0.337
C17.0 Duodenum	0.662	0.338
C22.1 Intrahepatic bile duct carcinoma	0.662	0.338
C78.2 Secondary malignant neoplasm of pleura	0.661	0.339
C69 Malignant neoplasm of eye and adnexa	0.660	0.340
C18.4 Transverse colon	0.660	0.340
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.660	0.340
M54.12 Radiculopathy (Cervical region)	0.659	0.341
T92.9 Sequelae of unspecified injury of upper limb	0.659	0.341
D03.4 Melanoma in situ of scalp and neck	0.658	0.342
C44.6 Skin of upper limb, including shoulder	0.658	0.342
C21 Malignant neoplasm of anus and anal canal	0.657	0.343
M53 Other dorsopathies, not elsewhere classified	0.656	0.344
F30.8 Other manic episodes	0.656	0.344
F30.1 Mania without psychotic symptoms	0.656	0.344
H33.5 Other retinal detachments	0.655	0.345
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.655	0.345
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.654	0.346
C70 Malignant neoplasm of meninges	0.654	0.346
C64-C68 Malignant neoplasms of urinary tract	0.654	0.346
S42 Fracture of shoulder and upper arm	0.654	0.346
S60-S69 Injuries to the wrist and hand	0.653	0.347
D05.7 Other carcinoma in situ of breast	0.651	0.349
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.650	0.350
T43.5 Other and unspecified antipsychotics and neuroleptics	0.650	0.350
M70-M79 Other soft tissue disorders	0.650	0.350
H53 Visual disturbances	0.649	0.351
M47.1 Other spondylosis with myelopathy	0.649	0.351
F33.1 Recurrent depressive disorder, current episode moderate	0.648	0.352
C18.5 Splenic flexure	0.648	0.352
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.647	0.353
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.646	0.353
D07 Carcinoma in situ of other and unspecified genital organs	0.646	0.354
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.645	0.355
T79-T79 Certain early complications of trauma	0.645	0.355
L75 Apocrine sweat disorders	0.644	0.356
L74 Eccrine sweat disorders	0.644	0.356
L68 Hypertrichosis	0.644	0.356
L67 Hair colour and hair shaft abnormalities	0.644	0.356
L66 Cicatricial alopecia [scarring hair loss]	0.644	0.356
L64 Androgenic alopecia	0.644	0.356
L63 Alopecia areata	0.644	0.356
L62 Nail disorders in diseases classified elsewhere	0.644	0.356
H50 Other strabismus	0.642	0.358
H40-H42 Glaucoma	0.641	0.359
H35.6 Retinal haemorrhage	0.639	0.361
H35.2 Other proliferative retinopathy	0.639	0.361
H35.1 Retinopathy of prematurity	0.639	0.361
D03.9 Melanoma in situ, unspecified	0.638	0.362
D03.8 Melanoma in situ of other sites	0.638	0.362
D03.2 Melanoma in situ of ear and external auricular canal	0.638	0.362
D03.1 Melanoma in situ of eyelid, including canthus	0.638	0.362
D03.0 Melanoma in situ of lip	0.638	0.362
L43 Lichen planus	0.638	0.362
C18.0 Caecum	0.638	0.362
H11 Other disorders of conjunctiva	0.637	0.363
T18 Foreign body in alimentary tract	0.637	0.363
L70.0 Acne vulgaris	0.636	0.364
M47.22 Other spondylosis with radiculopathy (Cervical region)	0.635	0.365
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.632	0.367
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.632	0.367
T41 Poisoning by anaesthetics and therapeutic gases	0.632	0.367
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.632	0.367
F32.2 Severe depressive episode without psychotic symptoms	0.631	0.369
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.631	0.369
M87 Osteonecrosis	0.630	0.370
M00 Pyogenic arthritis	0.628	0.372
C71.0 Cerebrum, except lobes and ventricles	0.628	0.372
H18.9 Disorder of cornea, unspecified	0.627	0.373
T43.3 Phenothiazine antipsychotics and neuroleptics	0.627	0.373
H55-H59 Other disorders of eye and adnexa	0.626	0.374
S92.1 Fracture of talus	0.626	0.374
S98 Traumatic amputation of ankle and foot	0.626	0.374
S97 Crushing injury of ankle and foot	0.626	0.374
S96 Injury of muscle and tendon at ankle and foot level	0.626	0.374
S95 Injury of blood vessels at ankle and foot level	0.626	0.374
S94 Injury of nerves at ankle and foot level	0.626	0.374
S90 Superficial injury of ankle and foot	0.626	0.374
H25-H28 Disorders of lens	0.626	0.374
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.625	0.375
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.625	0.375
H15 Disorders of sclera	0.625	0.375
H20 Iridocyclitis	0.625	0.375
T98 Sequelae of other and unspecified effects of external causes	0.625	0.375
S32 Fracture of lumbar spine and pelvis	0.623	0.377
F50 Eating disorders	0.623	0.377
T75 Effects of other external causes	0.622	0.377
T74 Maltreatment syndromes	0.622	0.377
T73 Effects of other deprivation	0.622	0.377
T70 Effects of air pressure and water pressure	0.622	0.377
T69 Other effects of reduced temperature	0.622	0.377
T67 Effects of heat and light	0.622	0.377
T71 Asphyxiation	0.622	0.377
T66 Unspecified effects of radiation	0.622	0.377
C15.5 Lower third of oesophagus	0.622	0.378
C71.2 Temporal lobe	0.622	0.378
T78.4 Allergy, unspecified	0.621	0.379
C15.9 Oesophagus, unspecified	0.620	0.380
L57.0 Actinic keratosis	0.619	0.381
T31 Burns classified according to extent of body surface involved	0.619	0.381
M54.59 Low back pain (Site unspecified)	0.618	0.382
L65 Other nonscarring hair loss	0.618	0.382
D05.0 Lobular carcinoma in situ	0.618	0.382
D04.3 Skin of other and unspecified parts of face	0.618	0.382
C71.3 Parietal lobe	0.617	0.382
C18.7 Sigmoid colon	0.617	0.383
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)	0.613	0.387
M47.95 Spondylosis, unspecified (Thoracolumbar region)	0.613	0.387
M47.93 Spondylosis, unspecified (Cervicothoracic region)	0.613	0.387
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)	0.613	0.387
M45 Ankylosing spondylitis	0.612	0.388
D03.3 Melanoma in situ of other and unspecified parts of face	0.612	0.388
H52 Disorders of refraction and accommodation	0.611	0.389
F53 Mental and behavioural disorders associated with the puerperium, not elsewhere classified	0.611	0.389
F51 Nonorganic sleep disorders	0.611	0.389
F59 Unspecified behavioural syndromes associated with physiological disturbances and physical factors	0.611	0.389
F55 Abuse of non-dependence-producing substances	0.611	0.389
F54 Psychological and behavioural factors associated with disorders or diseases classified elsewhere	0.611	0.389
M89 Other disorders of bone	0.611	0.389
T94 Sequelae of injuries involving multiple and unspecified body regions	0.609	0.391
M94 Other disorders of cartilage	0.608	0.392
C71.7 Brain stem	0.608	0.392
C71.6 Cerebellum	0.608	0.392
C71.5 Cerebral ventricle	0.608	0.392
C43.3 Malignant melanoma of other and unspecified parts of face	0.606	0.394
F84 Pervasive developmental disorders	0.605	0.394
T95 Sequelae of burns, corrosions and frostbite	0.605	0.395
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.605	0.395
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.605	0.395
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.603	0.397
C80 Malignant neoplasm without specification of site	0.600	0.400
M62 Other disorders of muscle	0.600	0.400
T46.4 Angiotensin-converting-enzyme inhibitors	0.600	0.400
L71.9 Rosacea, unspecified	0.599	0.401
T56 Toxic effect of metals	0.599	0.401
C22.9 Liver, unspecified	0.598	0.402
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.598	0.402
M90 Osteopathies in diseases classified elsewhere	0.597	0.403
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.596	0.403
C15.4 Middle third of oesophagus	0.596	0.404
H47.2 Optic atrophy	0.596	0.404
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.595	0.405
M80-M85 Disorders of bone density and structure	0.595	0.405
M48 Other spondylopathies	0.594	0.406
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.592	0.408
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.592	0.408
L73 Other follicular disorders	0.591	0.409
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.591	0.409
T91.3 Sequelae of injury of spinal cord	0.590	0.410
H33.0 Retinal detachment with retinal break	0.589	0.411
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.589	0.411
M46.9 Inflammatory spondylopathy, unspecified	0.588	0.412
T46.1 Calcium-channel blockers	0.587	0.413
L59 Other disorders of skin and subcutaneous tissue related to radiation	0.587	0.413
L58 Radiodermatitis	0.587	0.413
L56 Other acute skin changes due to ultraviolet radiation	0.587	0.413
L55 Sunburn	0.587	0.413
F23 Acute and transient psychotic disorders	0.585	0.415
L72.2 Steatocystoma multiplex	0.585	0.415
M92 Other juvenile osteochondrosis	0.584	0.416
D03.7 Melanoma in situ of lower limb, including hip	0.584	0.416
T92.8 Sequelae of other specified injuries of upper limb	0.584	0.416
H18.2 Other corneal oedema	0.582	0.418
C77.4 Inguinal and lower limb lymph nodes	0.582	0.418
F81 Specific developmental disorders of scholastic skills	0.582	0.418
S92.3 Fracture of metatarsal bone	0.581	0.419
F33.8 Other recurrent depressive disorders	0.581	0.419
F33.4 Recurrent depressive disorder, currently in remission	0.581	0.419
F33.0 Recurrent depressive disorder, current episode mild	0.581	0.419
H35.7 Separation of retinal layers	0.580	0.420
M50.9 Cervical disk disorder, unspecified	0.580	0.420
M50.8 Other cervical disk disorders	0.580	0.420
H43-H45 Disorders of vitreous body and globe	0.580	0.420
H18.1 Bullous keratopathy	0.579	0.420
C25.0 Head of pancreas	0.578	0.422
M77 Other enthesopathies	0.577	0.423
T19 Foreign body in genito-urinary tract	0.577	0.423
T15 Foreign body on external eye	0.577	0.423
T16 Foreign body in ear	0.577	0.423
H17.9 Corneal scar and opacity, unspecified	0.577	0.423
C71.9 Brain, unspecified	0.576	0.424
C15.8 Overlapping lesion of oesophagus	0.575	0.424
C15.3 Upper third of oesophagus	0.575	0.424
C15.2 Abdominal part of oesophagus	0.575	0.424
C15.1 Thoracic part of oesophagus	0.575	0.424
C15.0 Cervical part of oesophagus	0.575	0.424
M54.8 Other dorsalgia	0.574	0.426
M54.0 Panniculitis affecting regions of neck and back	0.574	0.426
S92.9 Fracture of foot, unspecified	0.574	0.426
S92.7 Multiple fractures of foot	0.574	0.426
S92.5 Fracture of other toe	0.574	0.426
S92.4 Fracture of great toe	0.574	0.426
S92.2 Fracture of other tarsal bone(s)	0.574	0.426
H33.4 Traction detachment of retina	0.574	0.426
T43.9 Psychotropic drug, unspecified	0.573	0.427
T43.8 Other psychotropic drugs, not elsewhere classified	0.573	0.427
T43.6 Psychostimulants with abuse potential	0.573	0.427
T43.4 Butyrophenone and thioxanthene neuroleptics	0.573	0.427
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.573	0.427
C32 Malignant neoplasm of larynx	0.572	0.428
C22.7 Other specified carcinomas of liver	0.572	0.428
C22.4 Other sarcomas of liver	0.572	0.428
C22.3 Angiosarcoma of liver	0.572	0.428
C22.2 Hepatoblastoma	0.572	0.428
H51 Other disorders of binocular movement	0.572	0.428
T92.1 Sequelae of fracture of arm	0.571	0.429
F32.8 Other depressive episodes	0.571	0.429
S50-S59 Injuries to the elbow and forearm	0.571	0.429
H18.6 Keratoconus	0.570	0.430
T91.1 Sequelae of fracture of spine	0.570	0.430
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.569	0.431
C76.0 Head, face and neck	0.569	0.431
T20 Burn and corrosion of head and neck	0.568	0.431
C17.8 Overlapping lesion of small intestine	0.568	0.431
C17.3 Meckel's diverticulum	0.568	0.431
C17.2 Ileum	0.568	0.431
C17.1 Jejunum	0.568	0.431
H49 Paralytic strabismus	0.568	0.432
H10 Conjunctivitis	0.568	0.432
C43.8 Overlapping malignant melanoma of skin	0.567	0.433
C43.2 Malignant melanoma of ear and external auricular canal	0.567	0.433
C43.1 Malignant melanoma of eyelid, including canthus	0.567	0.433
C43.0 Malignant melanoma of lip	0.567	0.433
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere	0.567	0.433
H53.4 Visual field defects	0.567	0.433
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.566	0.434
C24.1 Ampulla of Vater	0.565	0.435
S69 Other and unspecified injuries of wrist and hand	0.565	0.435
H35.0 Background retinopathy and retinal vascular changes	0.563	0.437
S30 Superficial injury of abdomen, lower back and pelvis	0.563	0.437
T78.9 Adverse effect, unspecified	0.562	0.437
T78.8 Other adverse effects, not elsewhere classified	0.562	0.437
T78.1 Other adverse food reactions, not elsewhere classified	0.562	0.437
T78.2 Anaphylactic shock, unspecified	0.562	0.438
M65-M68 Disorders of synovium and tendon	0.562	0.438
F32.1 Moderate depressive episode	0.562	0.438
S42.0 Fracture of clavicle	0.561	0.438
H13 Disorders of conjunctiva in diseases classified elsewhere	0.561	0.439
M54.2 Cervicalgia	0.561	0.439
H21.8 Other specified disorders of iris and ciliary body	0.560	0.440
C24.0 Extrahepatic bile duct	0.559	0.441
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)	0.559	0.441
C25.1 Body of pancreas	0.559	0.441
C43.4 Malignant melanoma of scalp and neck	0.558	0.441
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.558	0.442
T92.4 Sequelae of injury of nerve of upper limb	0.558	0.442
D04.5 Skin of trunk	0.558	0.442
T36.0 Penicillins	0.555	0.445
H53.0 Amblyopia ex anopsia	0.554	0.446
L60 Nail disorders	0.554	0.446
C17.9 Small intestine, unspecified	0.554	0.446
D04.7 Skin of lower limb, including hip	0.553	0.447
H16 Keratitis	0.553	0.447
M51.3 Other specified intervertebral disk degeneration	0.552	0.447
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy	0.552	0.447
M51.4 Schmorl's nodes	0.552	0.447
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.552	0.447
M02 Reactive arthropathies	0.552	0.447
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.552	0.447
L72.8 Other follicular cysts of skin and subcutaneous tissue	0.552	0.448
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.552	0.448
S37 Injury of urinary and pelvic organs	0.552	0.448
S36 Injury of intra-abdominal organs	0.552	0.448
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.552	0.448
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.552	0.448
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.552	0.448
S31 Open wound of abdomen, lower back and pelvis	0.552	0.448
M47.29 Other spondylosis with radiculopathy (Site unspecified)	0.551	0.448
M47.28 Other spondylosis with radiculopathy (Sacral and sacrococcygeal region)	0.551	0.448
M47.25 Other spondylosis with radiculopathy (Thoracolumbar region)	0.551	0.448

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations