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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117707626
log Bayes Factor = 12.1178
Chromosome 10   position 101,670,704  (GRCh37) Explore rs117707626 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
0.999 0.001 0.000
Chapter IX Diseases of the circulatory system
0.998 0.002 0.000
Chapter XIV Diseases of the genitourinary system
0.997 0.003 0.000
I30-I52 Other forms of heart disease
0.994 0.006 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.993 0.007 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.992 0.008 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.991 0.009 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.988 0.012 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.984 0.016 0.000
E70-E90 Metabolic disorders
0.981 0.019 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.980 0.020 0.000
N17-N19 Renal failure
0.980 0.020 0.000
I50 Heart failure
0.976 0.024 0.000
R50-R69 General symptoms and signs
0.976 0.024 0.000
N80 Endometriosis
0.974 0.026 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.973 0.027 0.000
Chapter X Diseases of the respiratory system
0.972 0.028 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.970 0.030 0.000
R55 Syncope and collapse
0.966 0.034 0.000
N88 Other noninflammatory disorders of cervix uteri
0.961 0.039 0.000
H30-H36 Disorders of choroid and retina
0.958 0.042 0.000
Chapter I Certain infectious and parasitic diseases
0.958 0.042 0.000
N86 Erosion and ectropion of cervix uteri
0.953 0.047 0.000
N80.9 Endometriosis, unspecified
0.951 0.049 0.000
I50.0 Congestive heart failure
0.944 0.056 0.000
E87.7 Fluid overload
0.944 0.056 0.000
Chapter V Mental and behavioural disorders
0.936 0.064 0.000
M45-M49 Spondylopathies
0.933 0.067 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.932 0.068 0.000
R56 Convulsions, not elsewhere classified
0.928 0.072 0.000
B95-B98 Bacterial, viral and other infectious agents
0.925 0.075 0.000
H53-H54 Visual disturbances and blindness
0.925 0.075 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.922 0.078 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.921 0.079 0.000
I45 Other conduction disorders
0.919 0.081 0.000
N18 Chronic renal failure
0.916 0.084 0.000
N17 Acute renal failure
0.916 0.084 0.000
H43-H45 Disorders of vitreous body and globe
0.909 0.091 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.909 0.091 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.908 0.092 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.907 0.093 0.000
J95-J99 Other diseases of the respiratory system
0.900 0.100 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.898 0.102 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.898 0.102 0.000
R56.8 Other and unspecified convulsions
0.893 0.107 0.000
M05-M14 Inflammatory polyarthropathies
0.893 0.107 0.000
N88.8 Other specified noninflammatory disorders of cervix uteri
0.891 0.109 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.890 0.110 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.889 0.111 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.884 0.116 0.000
N80.0 Endometriosis of uterus
0.882 0.118 0.000
H40-H42 Glaucoma
0.881 0.119 0.000
I47 Paroxysmal tachycardia
0.880 0.120 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.879 0.121 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.877 0.123 0.000
E87.2 Acidosis
0.876 0.124 0.000
E87.6 Hypokalaemia
0.874 0.126 0.000
N17.9 Acute renal failure, unspecified
0.871 0.129 0.000
I50.1 Left ventricular failure
0.868 0.132 0.000
H02 Other disorders of eyelid
0.868 0.132 0.000
J30-J39 Other diseases of upper respiratory tract
0.865 0.135 0.000
T66-T78 Other and unspecified effects of external causes
0.863 0.137 0.000
N89 Other noninflammatory disorders of vagina
0.862 0.138 0.000
H33 Retinal detachments and breaks
0.860 0.140 0.000
Chapter VIII Diseases of the ear and mastoid process
0.858 0.142 0.000
E20-E35 Disorders of other endocrine glands
0.857 0.143 0.000
I60-I69 Cerebrovascular diseases
0.857 0.143 0.000
J20-J22 Other acute lower respiratory infections
0.854 0.146 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.854 0.146 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.853 0.147 0.000
I44 Atrioventricular and left bundle-branch block
0.852 0.148 0.000
N97 Female infertility
0.848 0.152 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.848 0.152 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.848 0.152 0.000
H43 Disorders of vitreous body
0.845 0.155 0.000
N88.2 Stricture and stenosis of cervix uteri
0.845 0.155 0.000
I42 Cardiomyopathy
0.845 0.155 0.000
N18.9 Chronic renal failure, unspecified
0.843 0.157 0.000
I95 Hypotension
0.842 0.158 0.000
M65-M68 Disorders of synovium and tendon
0.841 0.159 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.839 0.161 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.837 0.163 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.834 0.166 0.000
M86-M90 Other osteopathies
0.834 0.166 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.833 0.167 0.000
S50-S59 Injuries to the elbow and forearm
0.832 0.168 0.000
I20-I25 Ischaemic heart diseases
0.830 0.170 0.000
I47.2 Ventricular tachycardia
0.826 0.174 0.000
E10-E14 Diabetes mellitus
0.825 0.175 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.824 0.176 0.000
J98 Other respiratory disorders
0.823 0.177 0.000
E87.0 Hyperosmolality and hypernatraemia
0.823 0.177 0.000
H33.3 Retinal breaks without detachment
0.820 0.180 0.000
H53 Visual disturbances
0.819 0.181 0.000
H02.8 Other specified disorders of eyelid
0.819 0.181 0.000
J40-J47 Chronic lower respiratory diseases
0.816 0.184 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.816 0.184 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.816 0.184 0.000
B35-B49 Mycoses
0.814 0.186 0.000
E40-E46 Malnutrition
0.814 0.186 0.000
M47 Spondylosis
0.810 0.190 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.809 0.191 0.000
M46 Other inflammatory spondylopathies
0.808 0.192 0.000
I95.9 Hypotension, unspecified
0.807 0.193 0.000
S90-S99 Injuries to the ankle and foot
0.804 0.196 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.803 0.197 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.802 0.197 0.000
M13 Other arthritis
0.801 0.199 0.000
H36 Retinal disorders in diseases classified elsewhere
0.799 0.201 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.798 0.202 0.000
H34 Retinal vascular occlusions
0.797 0.203 0.000
H40 Glaucoma
0.796 0.204 0.000
M48 Other spondylopathies
0.796 0.204 0.000
H54 Blindness and low vision
0.795 0.205 0.000
N92 Excessive, frequent and irregular menstruation
0.794 0.206 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.793 0.207 0.000
N72 Inflammatory disease of cervix uteri
0.792 0.208 0.000
J44 Other chronic obstructive pulmonary disease
0.787 0.213 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.787 0.213 0.000
H55-H59 Other disorders of eye and adnexa
0.783 0.217 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.782 0.218 0.000
R53 Malaise and fatigue
0.781 0.219 0.000
Chapter XXI Factors influencing health status and contact with health services
0.781 0.219 0.000
I37 Pulmonary valve disorders
0.780 0.220 0.000
M47.9 Spondylosis, unspecified
0.780 0.220 0.000
R51 Headache
0.779 0.221 0.000
T39.0 Salicylates
0.779 0.221 0.000
N89.8 Other specified noninflammatory disorders of vagina
0.778 0.222 0.000
N92.6 Irregular menstruation, unspecified
0.778 0.222 0.000
T42.4 Benzodiazepines
0.777 0.223 0.000
J98.4 Other disorders of lung
0.777 0.223 0.000
T39.1 4-Aminophenol derivatives
0.774 0.226 0.000
J22 Unspecified acute lower respiratory infection
0.770 0.230 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.770 0.230 0.000
T93 Sequelae of injuries of lower limb
0.768 0.232 0.000
H02.4 Ptosis of eyelid
0.768 0.232 0.000
E88 Other metabolic disorders
0.766 0.234 0.000
H04 Disorders of lachrymal system
0.765 0.235 0.000
T78 Adverse effects, not elsewhere classified
0.765 0.235 0.000
T79-T79 Certain early complications of trauma
0.764 0.236 0.000
I45.9 Conduction disorder, unspecified
0.764 0.236 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.764 0.236 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.764 0.236 0.000
T90 Sequelae of injuries of head
0.763 0.237 0.000
I45.2 Bifascicular block
0.763 0.237 0.000
Chapter XXII Codes for special purposes
0.761 0.239 0.000
R25 Abnormal involuntary movements
0.761 0.239 0.000
S60-S69 Injuries to the wrist and hand
0.760 0.240 0.000
I38 Endocarditis, valve unspecified
0.759 0.241 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.757 0.243 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.757 0.243 0.000
J00-J06 Acute upper respiratory infections
0.757 0.243 0.000
N18.3 Chronic kidney disease, stage 3
0.756 0.244 0.000
M67 Other disorders of synovium and tendon
0.755 0.245 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.755 0.245 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.754 0.246 0.000
Chapter VI Diseases of the nervous system
0.754 0.246 0.000
T88.7 Unspecified adverse effect of drug or medicament
0.754 0.246 0.000
R29.6 Tendency to fall, not elsewhere classified
0.754 0.246 0.000
N75 Diseases of Bartholin's gland
0.753 0.247 0.000
H43.1 Vitreous haemorrhage
0.753 0.247 0.000
N88.9 Noninflammatory disorder of cervix uteri, unspecified
0.752 0.248 0.000
Z60 Problems related to social environment
0.752 0.248 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.752 0.248 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.751 0.249 0.000
J39 Other diseases of upper respiratory tract
0.751 0.249 0.000
S20-S29 Injuries to the thorax
0.750 0.250 0.000
E73 Lactose intolerance
0.749 0.251 0.000
N80.8 Other endometriosis
0.749 0.251 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.748 0.252 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.747 0.253 0.000
N19 Unspecified renal failure
0.747 0.253 0.000
N97.9 Female infertility, unspecified
0.745 0.255 0.000
Z60.2 Living alone
0.744 0.256 0.000
N85.0 Endometrial glandular hyperplasia
0.743 0.257 0.000
F03 Unspecified dementia
0.740 0.260 0.000
R52 Pain, not elsewhere classified
0.740 0.260 0.000
M13.9 Arthritis, unspecified
0.738 0.262 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.737 0.263 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.736 0.264 0.000
M20-M25 Other joint disorders
0.736 0.264 0.000
R68 Other general symptoms and signs
0.735 0.265 0.000
A30-A49 Other bacterial diseases
0.734 0.265 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.731 0.269 0.000
I45.3 Trifascicular block
0.730 0.270 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.729 0.271 0.000
N76 Other inflammation of vagina and vulva
0.729 0.271 0.000
I77 Other disorders of arteries and arterioles
0.729 0.271 0.000
H35 Other retinal disorders
0.728 0.272 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.727 0.273 0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract
0.726 0.274 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.726 0.274 0.000
M10 Gout
0.724 0.276 0.000
R57 Shock, not elsewhere classified
0.723 0.277 0.000
S10-S19 Injuries to the neck
0.723 0.277 0.000
S50 Superficial injury of forearm
0.723 0.277 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.723 0.277 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.723 0.277 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.721 0.279 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.720 0.280 0.000
H43.3 Other vitreous opacities
0.719 0.281 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.719 0.281 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.719 0.281 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.716 0.284 0.000
H10-H13 Disorders of conjunctiva
0.716 0.284 0.000
I00-I02 Acute rheumatic fever
0.715 0.285 0.000
E10 Insulin-dependent diabetes mellitus
0.714 0.286 0.000
I52 Other heart disorders in diseases classified elsewhere
0.712 0.287 0.000
I48 Atrial fibrillation and flutter
0.712 0.287 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.712 0.287 0.000
I41 Myocarditis in diseases classified elsewhere
0.712 0.287 0.000
I40 Acute myocarditis
0.712 0.287 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.712 0.287 0.000
I36 Nonrheumatic tricuspid valve disorders
0.712 0.287 0.000
I32 Pericarditis in diseases classified elsewhere
0.712 0.287 0.000
N98 Complications associated with artificial fertilisation
0.712 0.288 0.000
N91 Absent, scanty and rare menstruation
0.712 0.288 0.000
N82 Fistulae involving female genital tract
0.712 0.288 0.000
N96 Habitual aborter
0.712 0.288 0.000
T86 Failure and rejection of transplanted organs and tissues
0.712 0.288 0.000
M89 Other disorders of bone
0.712 0.288 0.000
T87 Complications peculiar to reattachment and amputation
0.711 0.289 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.711 0.289 0.000
B25-B34 Other viral diseases
0.711 0.289 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.711 0.289 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.710 0.290 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.710 0.290 0.000
I44.7 Left bundle-branch block, unspecified
0.709 0.291 0.000
F99-F99 Unspecified mental disorder
0.709 0.291 0.000
R30-R39 Symptoms and signs involving the urinary system
0.709 0.291 0.000
H53.0 Amblyopia ex anopsia
0.709 0.291 0.000
I45.1 Other and unspecified right bundle-branch block
0.709 0.291 0.000
N25-N29 Other disorders of kidney and ureter
0.708 0.292 0.000
I34 Nonrheumatic mitral valve disorders
0.708 0.292 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.708 0.292 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.707 0.292 0.000
I50.9 Heart failure, unspecified
0.707 0.293 0.000
R27 Other lack of coordination
0.707 0.293 0.000
G90-G99 Other disorders of the nervous system
0.707 0.293 0.000
N85.9 Noninflammatory disorder of uterus, unspecified
0.706 0.294 0.000
I21 Acute myocardial infarction
0.706 0.294 0.000
J36 Peritonsillar abscess
0.705 0.295 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.705 0.295 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.705 0.295 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.705 0.295 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.705 0.295 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.705 0.295 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.705 0.295 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.705 0.295 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.705 0.295 0.000
T36 Poisoning by systemic antibiotics
0.705 0.295 0.000
E27 Other disorders of adrenal gland
0.705 0.295 0.000
E85 Amyloidosis
0.704 0.296 0.000
E84 Cystic fibrosis
0.704 0.296 0.000
E79 Disorders of purine and pyrimidine metabolism
0.704 0.296 0.000
E77 Disorders of glycoprotein metabolism
0.704 0.296 0.000
E76 Disorders of glycosaminoglycan metabolism
0.704 0.296 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.704 0.296 0.000
E74 Other disorders of carbohydrate metabolism
0.704 0.296 0.000
E72 Other disorders of amino-acid metabolism
0.704 0.296 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.704 0.296 0.000
E70 Disorders of aromatic amino-acid metabolism
0.704 0.296 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.704 0.296 0.000
N18.0 End-stage renal disease
0.703 0.296 0.000
Chapter XX External causes of morbidity and mortality
0.703 0.296 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.703 0.297 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.703 0.297 0.000
E87.4 Mixed disorder of acid-base balance
0.703 0.297 0.000
E87.3 Alkalosis
0.703 0.297 0.000
Q60-Q64 Congenital malformations of the urinary system
0.701 0.299 0.000
H02.3 Blepharochalasis
0.701 0.299 0.000
R63 Symptoms and signs concerning food and fluid intake
0.700 0.300 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.700 0.300 0.000
R62 Lack of expected normal physiological development
0.700 0.300 0.000
R64 Cachexia
0.700 0.300 0.000
R58 Haemorrhage, not elsewhere classified
0.700 0.300 0.000
I33 Acute and subacute endocarditis
0.699 0.301 0.000
T92 Sequelae of injuries of upper limb
0.699 0.301 0.000
M48.0 Spinal stenosis
0.698 0.302 0.000
N80.6 Endometriosis in cutaneous scar
0.698 0.302 0.000
N80.5 Endometriosis of intestine
0.698 0.302 0.000
N80.4 Endometriosis of rectovaginal septum and vagina
0.698 0.302 0.000
N80.2 Endometriosis of Fallopian tube
0.698 0.302 0.000
R31 Unspecified haematuria
0.698 0.302 0.000
M91-M94 Chondropathies
0.698 0.302 0.000
M60-M63 Disorders of muscles
0.698 0.302 0.000
M00-M03 Infectious arthropathies
0.698 0.302 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.697 0.303 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.697 0.303 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.697 0.303 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.697 0.303 0.000
N85.2 Hypertrophy of uterus
0.696 0.303 0.000
E28 Ovarian dysfunction
0.696 0.304 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.695 0.305 0.000
T85.2 Mechanical complication of intraocular lens
0.695 0.305 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.695 0.305 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.695 0.305 0.000
R47-R49 Symptoms and signs involving speech and voice
0.695 0.305 0.000
E83 Disorders of mineral metabolism
0.694 0.306 0.000
I05-I09 Chronic rheumatic heart diseases
0.693 0.307 0.000
M40-M43 Deforming dorsopathies
0.692 0.308 0.000
H60-H62 Diseases of external ear
0.692 0.308 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.692 0.308 0.000
N18.5 Chronic kidney disease, stage 5
0.691 0.308 0.000
J35 Chronic diseases of tonsils and adenoids
0.690 0.310 0.000
M06 Other rheumatoid arthritis
0.690 0.310 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.690 0.310 0.000
I30 Acute pericarditis
0.690 0.310 0.000
N88.4 Hypertrophic elongation of cervix uteri
0.689 0.311 0.000
N88.3 Incompetence of cervix uteri
0.689 0.311 0.000
N88.1 Old laceration of cervix uteri
0.689 0.311 0.000
N88.0 Leukoplakia of cervix uteri
0.689 0.311 0.000
Q00-Q07 Congenital malformations of the nervous system
0.689 0.311 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.688 0.312 0.000
N70 Salpingitis and oophoritis
0.688 0.312 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.688 0.312 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.687 0.313 0.000
H31 Other disorders of choroid
0.687 0.313 0.000
H30 Chorioretinal inflammation
0.687 0.313 0.000
B99-B99 Other infectious diseases
0.687 0.313 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.687 0.313 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.687 0.313 0.000
B65-B83 Helminthiases
0.687 0.313 0.000
B50-B64 Protozoal diseases
0.687 0.313 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.687 0.313 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.687 0.313 0.000
A80-A89 Viral infections of the central nervous system
0.687 0.313 0.000
A75-A79 Rickettsioses
0.687 0.313 0.000
A70-A74 Other diseases caused by chlamydiae
0.687 0.313 0.000
A65-A69 Other spirochaetal diseases
0.687 0.313 0.000
A20-A28 Certain zoonotic bacterial diseases
0.687 0.313 0.000
A15-A19 Tuberculosis
0.687 0.313 0.000
E46 Unspecified protein-energy malnutrition
0.687 0.313 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.687 0.313 0.000
N71 Inflammatory disease of uterus, except cervix
0.686 0.314 0.000
E11 Non-insulin-dependent diabetes mellitus
0.685 0.315 0.000
N00-N08 Glomerular diseases
0.685 0.315 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.684 0.316 0.000
H36.0 Diabetic retinopathy
0.684 0.316 0.000
I45.5 Other specified heart block
0.684 0.316 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.684 0.316 0.000
H05 Disorders of orbit
0.683 0.316 0.000
H65-H75 Diseases of middle ear and mastoid
0.682 0.318 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.682 0.318 0.000
H02.6 Xanthelasma of eyelid
0.681 0.319 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.681 0.319 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.681 0.319 0.000
H40.2 Primary angle-closure glaucoma
0.680 0.320 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.679 0.321 0.000
E23 Hypofunction and other disorders of pituitary gland
0.678 0.322 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.677 0.323 0.000
M45 Ankylosing spondylitis
0.675 0.325 0.000
R54 Senility
0.674 0.325 0.000
H90-H95 Other disorders of ear
0.674 0.326 0.000
M80-M85 Disorders of bone density and structure
0.673 0.327 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.673 0.327 0.000
S40-S49 Injuries to the shoulder and upper arm
0.673 0.327 0.000
Z09.0 Follow-up examination after surgery for other conditions
0.673 0.327 0.000
Q50-Q56 Congenital malformations of genital organs
0.672 0.328 0.000
I10-I15 Hypertensive diseases
0.671 0.329 0.000
I44.3 Other and unspecified atrioventricular block
0.671 0.329 0.000
M67.8 Other specified disorders of synovium and tendon
0.671 0.329 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.671 0.329 0.000
F70-F79 Mental retardation
0.671 0.329 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.671 0.329 0.000
S51 Open wound of forearm
0.671 0.329 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.670 0.330 0.000
Q80-Q89 Other congenital malformations
0.670 0.330 0.000
H53.1 Subjective visual disturbances
0.670 0.330 0.000
F60-F69 Disorders of adult personality and behaviour
0.669 0.330 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.669 0.330 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.669 0.331 0.000
I24 Other acute ischaemic heart diseases
0.669 0.331 0.000
M49 Spondylopathies in diseases classified elsewhere
0.669 0.331 0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft
0.668 0.331 0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract
0.668 0.331 0.000
T83.2 Mechanical complication of graft of urinary organ
0.668 0.331 0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)
0.667 0.333 0.000
I63 Cerebral infarction
0.667 0.333 0.000
H02.0 Entropion and trichiasis of eyelid
0.667 0.333 0.000
R56.0 Febrile convulsions
0.665 0.335 0.000
F80-F89 Disorders of psychological development
0.665 0.335 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.664 0.336 0.000
S92 Fracture of foot, except ankle
0.663 0.337 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.663 0.337 0.000
B37 Candidiasis
0.663 0.337 0.000
E22 Hyperfunction of pituitary gland
0.662 0.337 0.000
I42.0 Dilated cardiomyopathy
0.662 0.338 0.000
N10-N16 Renal tubulo-interstitial diseases
0.662 0.338 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.661 0.339 0.000
T51 Toxic effect of alcohol
0.661 0.339 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.661 0.339 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.661 0.339 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.660 0.339 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.660 0.340 0.000
R20 Disturbances of skin sensation
0.659 0.341 0.000
I45.8 Other specified conduction disorders
0.659 0.341 0.000
I45.4 Nonspecific intraventricular block
0.659 0.341 0.000
I45.0 Right fascicular block
0.659 0.341 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.659 0.341 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.658 0.342 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.658 0.342 0.000
I69 Sequelae of cerebrovascular disease
0.658 0.342 0.000
N18.8 Other chronic renal failure
0.657 0.343 0.000
N18.1 Chronic kidney disease, stage 1
0.657 0.343 0.000
E50-E64 Other nutritional deficiencies
0.657 0.343 0.000
N17.8 Other acute renal failure
0.657 0.343 0.000
N17.2 Acute renal failure with medullary necrosis
0.657 0.343 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.657 0.343 0.000
N17.0 Acute renal failure with tubular necrosis
0.657 0.343 0.000
N85.4 Malposition of uterus
0.657 0.343 0.000
I44.1 Atrioventricular block, second degree
0.657 0.343 0.000
Z13 Special screening examination for other diseases and disorders
0.654 0.346 0.000
I42.8 Other cardiomyopathies
0.654 0.346 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.654 0.346 0.000
T78.4 Allergy, unspecified
0.654 0.346 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.652 0.348 0.000
H44 Disorders of globe
0.652 0.348 0.000
T98 Sequelae of other and unspecified effects of external causes
0.652 0.348 0.000
T95 Sequelae of burns, corrosions and frostbite
0.652 0.348 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.652 0.348 0.000
T91 Sequelae of injuries of neck and trunk
0.652 0.348 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.652 0.348 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.652 0.348 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.652 0.348 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.650 0.350 0.000
I99 Other and unspecified disorders of circulatory system
0.650 0.350 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.650 0.350 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.650 0.350 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.647 0.353 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.647 0.353 0.000
T78.3 Angioneurotic oedema
0.647 0.353 0.000
T93.2 Sequelae of other fractures of lower limb
0.646 0.354 0.000
S50.9 Superficial injury of forearm, unspecified
0.645 0.355 0.000
J96 Respiratory failure, not elsewhere classified
0.645 0.355 0.000
H57 Other disorders of eye and adnexa
0.644 0.356 0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified
0.644 0.356 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.644 0.356 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.644 0.356 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.644 0.356 0.000
T42.3 Barbiturates
0.644 0.356 0.000
T42.2 Succinimides and oxazolidinediones
0.644 0.356 0.000
T42.1 Iminostilbenes
0.644 0.356 0.000
T42.0 Hydantoin derivatives
0.644 0.356 0.000
E87.5 Hyperkalaemia
0.644 0.356 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.643 0.356 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.643 0.356 0.000
T39.4 Antirheumatics, not elsewhere classified
0.643 0.356 0.000
T39.2 Pyrazolone derivatives
0.643 0.356 0.000
B15-B19 Viral hepatitis
0.643 0.357 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.643 0.357 0.000
M86 Osteomyelitis
0.642 0.358 0.000
M05 Seropositive rheumatoid arthritis
0.642 0.358 0.000
Z01.6 Radiological examination, not elsewhere classified
0.642 0.358 0.000
N73 Other female pelvic inflammatory diseases
0.641 0.359 0.000
I22 Subsequent myocardial infarction
0.641 0.359 0.000
J30 Vasomotor and allergic rhinitis
0.640 0.360 0.000
S70-S79 Injuries to the hip and thigh
0.640 0.360 0.000
H54.4 Blindness, one eye
0.640 0.360 0.000
M14 Arthropathies in other diseases classified elsewhere
0.640 0.360 0.000
M12 Other specific arthropathies
0.640 0.360 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.640 0.360 0.000
M08 Juvenile arthritis
0.640 0.360 0.000
I45.6 Preexcitation syndrome
0.640 0.360 0.000
I42.2 Other hypertrophic cardiomyopathy
0.638 0.361 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.637 0.362 0.000
Q35-Q37 Cleft lip and cleft palate
0.637 0.362 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.637 0.362 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.637 0.362 0.000
N85.1 Endometrial adenomatous hyperplasia
0.637 0.363 0.000
N18.2 Chronic kidney disease, stage 2
0.637 0.363 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.637 0.363 0.000
M11 Other crystal arthropathies
0.636 0.364 0.000
H34.2 Other retinal artery occlusions
0.636 0.364 0.000
H34.8 Other retinal vascular occlusions
0.635 0.365 0.000
R59 Enlarged lymph nodes
0.634 0.366 0.000
B35 Dermatophytosis
0.634 0.366 0.000
H04.1 Other disorders of lachrymal gland
0.634 0.366 0.000
I46 Cardiac arrest
0.634 0.366 0.000
T31 Burns classified according to extent of body surface involved
0.634 0.366 0.000
I60 Subarachnoid haemorrhage
0.634 0.366 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.633 0.367 0.000
I62 Other nontraumatic intracranial haemorrhage
0.632 0.368 0.000
H42 Glaucoma in diseases classified elsewhere
0.631 0.368 0.000
I47.0 Reentry ventricular arrhythmia
0.631 0.369 0.000
T90.2 Sequelae of fracture of skull and facial bones
0.631 0.369 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.630 0.370 0.000
N85.7 Haematometra
0.630 0.370 0.000
N85.6 Intra-uterine synechiae
0.630 0.370 0.000
N85.5 Inversion of uterus
0.630 0.370 0.000
N85.3 Subinvolution of uterus
0.630 0.370 0.000
H33.2 Serous retinal detachment
0.629 0.371 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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