TreeWAS – Variant ID: rs11784833

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
N02.9 Unspecified	0.347	0.653	0.000
N02 Recurrent and persistent haematuria	0.321	0.679	0.000
N02.8 Other	0.301	0.699	0.000
N00-N08 Glomerular diseases	0.244	0.756	0.000
N02.7 Diffuse crescentic glomerulonephritis	0.230	0.770	0.000
N02.6 Dense deposit disease	0.230	0.770	0.000
N02.5 Diffuse mesangiocapillary glomerulonephritis	0.230	0.770	0.000
N02.4 Diffuse endocapillary proliferative glomerulonephritis	0.230	0.770	0.000
N02.1 Focal and segmental glomerular lesions	0.230	0.770	0.000
N02.0 Minor glomerular abnormality	0.230	0.770	0.000
N02.2 Diffuse membranous glomerulonephritis	0.229	0.771	0.000
N03 Chronic nephritic syndrome	0.222	0.778	0.000
N02.3 Diffuse mesangial proliferative glomerulonephritis	0.220	0.780	0.000
N08 Glomerular disorders in diseases classified elsewhere	0.218	0.782	0.000
N03.9 Unspecified	0.187	0.813	0.000
N08.3 Glomerular disorders in diabetes mellitus	0.184	0.816	0.000
N03.5 Diffuse mesangiocapillary glomerulonephritis	0.179	0.821	0.000
N08.5 Glomerular disorders in systemic connective tissue disorders	0.179	0.821	0.000
N03.8 Other	0.177	0.823	0.000
N07 Hereditary nephropathy, not elsewhere classified	0.175	0.825	0.000
N06 Isolated proteinuria with specified morphological lesion	0.175	0.825	0.000
N01 Rapidly progressive nephritic syndrome	0.175	0.825	0.000
N00 Acute nephritic syndrome	0.166	0.834	0.000
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases	0.164	0.836	0.000
N03.1 Focal and segmental glomerular lesions	0.162	0.837	0.000
N05 Unspecified nephritic syndrome	0.159	0.841	0.000
N03.7 Diffuse crescentic glomerulonephritis	0.159	0.841	0.000
N03.6 Dense deposit disease	0.159	0.841	0.000
N03.4 Diffuse endocapillary proliferative glomerulonephritis	0.159	0.841	0.000
N03.3 Diffuse mesangial proliferative glomerulonephritis	0.159	0.841	0.000
N03.2 Diffuse membranous glomerulonephritis	0.159	0.841	0.000
N03.0 Minor glomerular abnormality	0.159	0.841	0.000
N08.8 Glomerular disorders in other diseases classified elsewhere	0.156	0.844	0.000
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism	0.156	0.844	0.000
N08.1 Glomerular disorders in neoplastic diseases	0.156	0.844	0.000
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere	0.156	0.844	0.000
N04 Nephrotic syndrome	0.155	0.845	0.000
N05.8 Other	0.133	0.867	0.000
N01.9 Unspecified	0.126	0.874	0.000
N01.8 Other	0.126	0.874	0.000
N01.7 Diffuse crescentic glomerulonephritis	0.126	0.874	0.000
N01.6 Dense deposit disease	0.126	0.874	0.000
N01.5 Diffuse mesangiocapillary glomerulonephritis	0.126	0.874	0.000
N01.4 Diffuse endocapillary proliferative glomerulonephritis	0.126	0.874	0.000
N01.3 Diffuse mesangial proliferative glomerulonephritis	0.126	0.874	0.000
N01.2 Diffuse membranous glomerulonephritis	0.126	0.874	0.000
N01.1 Focal and segmental glomerular lesions	0.126	0.874	0.000
N01.0 Minor glomerular abnormality	0.126	0.874	0.000
N06.9 Unspecified	0.126	0.874	0.000
N06.8 Other	0.126	0.874	0.000
N06.7 Diffuse crescentic glomerulonephritis	0.126	0.874	0.000
N06.6 Dense deposit disease	0.126	0.874	0.000
N06.5 Diffuse mesangiocapillary glomerulonephritis	0.126	0.874	0.000
N06.4 Diffuse endocapillary proliferative glomerulonephritis	0.126	0.874	0.000
N06.3 Diffuse mesangial proliferative glomerulonephritis	0.126	0.874	0.000
N06.2 Diffuse membranous glomerulonephritis	0.126	0.874	0.000
N06.1 Focal and segmental glomerular lesions	0.126	0.874	0.000
N06.0 Minor glomerular abnormality	0.126	0.874	0.000
N07.9 Unspecified	0.126	0.874	0.000
N07.8 Other	0.126	0.874	0.000
N07.7 Diffuse crescentic glomerulonephritis	0.126	0.874	0.000
N07.6 Dense deposit disease	0.126	0.874	0.000
N07.5 Diffuse mesangiocapillary glomerulonephritis	0.126	0.874	0.000
N07.4 Diffuse endocapillary proliferative glomerulonephritis	0.126	0.874	0.000
N07.3 Diffuse mesangial proliferative glomerulonephritis	0.126	0.874	0.000
N07.2 Diffuse membranous glomerulonephritis	0.126	0.874	0.000
N07.1 Focal and segmental glomerular lesions	0.126	0.874	0.000
N07.0 Minor glomerular abnormality	0.126	0.874	0.000
N05.2 Diffuse membranous glomerulonephritis	0.124	0.876	0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis	0.122	0.878	0.000
N00.8 Other	0.119	0.881	0.000
N00.7 Diffuse crescentic glomerulonephritis	0.119	0.881	0.000
N00.6 Dense deposit disease	0.119	0.881	0.000
N00.5 Diffuse mesangiocapillary glomerulonephritis	0.119	0.881	0.000
N00.4 Diffuse endocapillary proliferative glomerulonephritis	0.119	0.881	0.000
N00.3 Diffuse mesangial proliferative glomerulonephritis	0.119	0.881	0.000
N00.2 Diffuse membranous glomerulonephritis	0.119	0.881	0.000
N00.1 Focal and segmental glomerular lesions	0.119	0.881	0.000
N00.0 Minor glomerular abnormality	0.119	0.881	0.000
N04.1 Focal and segmental glomerular lesions	0.115	0.884	0.000
N05.6 Dense deposit disease	0.114	0.886	0.000
N05.4 Diffuse endocapillary proliferative glomerulonephritis	0.114	0.886	0.000
N05.0 Minor glomerular abnormality	0.114	0.886	0.000
N05.7 Diffuse crescentic glomerulonephritis	0.112	0.888	0.000
N04.8 Other	0.111	0.888	0.000
N04.7 Diffuse crescentic glomerulonephritis	0.111	0.888	0.000
N04.6 Dense deposit disease	0.111	0.888	0.000
N04.5 Diffuse mesangiocapillary glomerulonephritis	0.111	0.888	0.000
N04.4 Diffuse endocapillary proliferative glomerulonephritis	0.111	0.888	0.000
N04.3 Diffuse mesangial proliferative glomerulonephritis	0.111	0.888	0.000
N04.0 Minor glomerular abnormality	0.111	0.888	0.000
N00.9 Unspecified	0.110	0.890	0.000
N04.2 Diffuse membranous glomerulonephritis	0.106	0.893	0.000
N05.3 Diffuse mesangial proliferative glomerulonephritis	0.104	0.896	0.000
N05.1 Focal and segmental glomerular lesions	0.099	0.900	0.000
N04.9 Unspecified	0.092	0.908	0.000
N05.9 Unspecified	0.069	0.931	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.053	0.947	0.000
I71 Aortic aneurysm and dissection	0.048	0.952	0.000
I70 Atherosclerosis	0.044	0.956	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.043	0.957	0.000
I70.0 Atherosclerosis of aorta	0.042	0.958	0.000
I77.6 Arteritis, unspecified	0.042	0.958	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.041	0.958	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.041	0.959	0.000
I77 Other disorders of arteries and arterioles	0.041	0.959	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.038	0.962	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.038	0.962	0.000
I71.0 Dissection of aorta [any part]	0.038	0.962	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.037	0.963	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.037	0.963	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.036	0.964	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.035	0.965	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.035	0.965	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.035	0.965	0.000
I70.8 Atherosclerosis of other arteries	0.035	0.965	0.000
I77.2 Rupture of artery	0.034	0.966	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.033	0.967	0.000
I73 Other peripheral vascular diseases	0.032	0.968	0.000
I70.9 Generalised and unspecified atherosclerosis	0.032	0.968	0.000
I74 Arterial embolism and thrombosis	0.032	0.968	0.000
Z95.0 Presence of cardiac pacemaker	0.031	0.969	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.031	0.969	0.000
I46.0 Cardiac arrest with successful resuscitation	0.030	0.970	0.000
I77.5 Necrosis of artery	0.029	0.970	0.000
I77.4 Coeliac artery compression syndrome	0.029	0.970	0.000
I77.0 Arteriovenous fistula, acquired	0.029	0.971	0.000
I77.3 Arterial fibromuscular dysplasia	0.029	0.971	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.029	0.971	0.000
I70.1 Atherosclerosis of renal artery	0.028	0.971	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.028	0.972	0.000
I77.1 Stricture of artery	0.027	0.973	0.000
I73.9 Peripheral vascular disease, unspecified	0.027	0.973	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.027	0.973	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.027	0.973	0.000
I24 Other acute ischaemic heart diseases	0.026	0.974	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.026	0.974	0.000
I73.8 Other specified peripheral vascular diseases	0.026	0.974	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.025	0.974	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.025	0.975	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.025	0.975	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.025	0.975	0.000
E27.1 Primary adrenocortical insufficiency	0.025	0.975	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.024	0.976	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.023	0.977	0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.023	0.977	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.023	0.977	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.022	0.978	0.000
E27 Other disorders of adrenal gland	0.022	0.978	0.000
I72 Other aneurysm	0.022	0.978	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.021	0.979	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.021	0.979	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.020	0.979	0.000
I78 Diseases of capillaries	0.021	0.979	0.000
I24.1 Dressler's syndrome	0.020	0.980	0.000
E27.8 Other specified disorders of adrenal gland	0.020	0.980	0.000
I46 Cardiac arrest	0.020	0.980	0.000
I74.8 Embolism and thrombosis of other arteries	0.019	0.980	0.000
D27 Benign neoplasm of ovary	0.019	0.981	0.000
I72.3 Aneurysm of iliac artery	0.019	0.981	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.019	0.981	0.000
I79.1 Aortitis in diseases classified elsewhere	0.018	0.982	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.018	0.982	0.000
I46.9 Cardiac arrest, unspecified	0.018	0.982	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.018	0.982	0.000
I72.1 Aneurysm of artery of upper extremity	0.017	0.982	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.017	0.983	0.000
I77.8 Other specified disorders of arteries and arterioles	0.016	0.983	0.000
E27.2 Addisonian crisis	0.016	0.984	0.000
E27.5 Adrenomedullary hyperfunction	0.016	0.984	0.000
E27.0 Other adrenocortical overactivity	0.016	0.984	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.016	0.984	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.016	0.984	0.000
I72.8 Aneurysm of other specified arteries	0.016	0.984	0.000
I74.5 Embolism and thrombosis of iliac artery	0.016	0.984	0.000
I72.9 Aneurysm of unspecified site	0.015	0.985	0.000
I78.9 Disease of capillaries, unspecified	0.015	0.985	0.000
I72.2 Aneurysm of renal artery	0.014	0.986	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.014	0.986	0.000
I46.1 Sudden cardiac death, so described	0.014	0.986	0.000
I78.8 Other diseases of capillaries	0.014	0.986	0.000
K29.0 Acute haemorrhagic gastritis	0.014	0.986	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.013	0.987	0.000
M20.0 Deformity of finger(s)	0.000	0.988	0.012
E27.9 Disorder of adrenal gland, unspecified	0.011	0.989	0.000
I72.4 Aneurysm of artery of lower extremity	0.009	0.990	0.000
F05.9 Delirium, unspecified	0.010	0.990	0.000
I72.0 Aneurysm of carotid artery	0.009	0.991	0.000
I73.0 Raynaud's syndrome	0.009	0.991	0.000
M25.50 Pain in joint (Multiple sites)	0.009	0.991	0.000
I44.7 Left bundle-branch block, unspecified	0.008	0.992	0.000
S60.8 Other superficial injuries of wrist and hand	0.008	0.992	0.000
I24.8 Other forms of acute ischaemic heart disease	0.008	0.992	0.000
S60.2 Contusion of other parts of wrist and hand	0.008	0.992	0.000
L95.9 Vasculitis limited to skin, unspecified	0.008	0.992	0.000
S60 Superficial injury of wrist and hand	0.008	0.992	0.000
I78.1 Naevus, nonneoplastic	0.008	0.992	0.000
N18.9 Chronic renal failure, unspecified	0.007	0.993	0.000
S60.9 Superficial injury of wrist and hand, unspecified	0.007	0.993	0.000
K62.6 Ulcer of anus and rectum	0.000	0.993	0.007
S60.1 Contusion of finger(s) with damage to nail	0.006	0.994	0.000
S60.7 Multiple superficial injuries of wrist and hand	0.006	0.994	0.000
F05 Delirium, not induced by alcohol and other psychoactive substances	0.006	0.994	0.000
M31.3 Wegener's granulomatosis	0.006	0.994	0.000
U80.8 Agent resistant to other penicillin-related antibiotic	0.000	0.994	0.006
E10.3 With ophthalmic complications	0.006	0.994	0.000
F05.8 Other delirium	0.006	0.994	0.000
S43.0 Dislocation of shoulder joint	0.005	0.995	0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.000	0.995	0.005
K55.0 Acute vascular disorders of intestine	0.005	0.995	0.000
F05.0 Delirium not superimposed on dementia, so described	0.005	0.995	0.000
K55.9 Vascular disorder of intestine, unspecified	0.005	0.995	0.000
F05.1 Delirium superimposed on dementia	0.005	0.995	0.000
S60.0 Contusion of finger(s) without damage to nail	0.005	0.995	0.000
K55 Vascular disorders of intestine	0.004	0.996	0.000
E10 Insulin-dependent diabetes mellitus	0.004	0.996	0.000
R27.8 Other and unspecified lack of coordination	0.000	0.996	0.004
K55.1 Chronic vascular disorders of intestine	0.004	0.996	0.000
E10.1 With ketoacidosis	0.004	0.996	0.000
M31 Other necrotising vasculopathies	0.004	0.996	0.000
E10.7 With multiple complications	0.004	0.996	0.000
S99.9 Unspecified injury of ankle and foot	0.004	0.996	0.000
E10.5 With peripheral circulatory complications	0.004	0.996	0.000
K55.8 Other vascular disorders of intestine	0.004	0.996	0.000
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s	0.000	0.996	0.004
E10.0 With coma	0.004	0.996	0.000
E10.6 With other specified complications	0.004	0.996	0.000
L95 Vasculitis limited to skin, not elsewhere classified	0.004	0.996	0.000
M31.9 Necrotising vasculopathy, unspecified	0.003	0.996	0.000
M31.7 Microscopic polyangiitis	0.003	0.997	0.000
M31.1 Thrombotic microangiopathy	0.003	0.997	0.000
M31.0 Hypersensitivity angiitis	0.003	0.997	0.000
E10.2 With renal complications	0.003	0.997	0.000
H80.9 Otosclerosis, unspecified	0.000	0.997	0.003
M31.8 Other specified necrotising vasculopathies	0.003	0.997	0.000
T88.7 Unspecified adverse effect of drug or medicament	0.003	0.997	0.000
S99 Other and unspecified injuries of ankle and foot	0.003	0.997	0.000
S99.8 Other specified injuries of ankle and foot	0.003	0.997	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.003	0.997	0.000
M31.2 Lethal midline granuloma	0.003	0.997	0.000
M31.6 Other giant cell arteritis	0.003	0.997	0.000
E10.8 With unspecified complications	0.003	0.997	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.003	0.997	0.000
H52.1 Myopia	0.000	0.997	0.003
R49.8 Other and unspecified voice disturbances	0.003	0.997	0.000
L95.8 Other vasculitis limited to skin	0.003	0.997	0.000
R49.0 Dysphonia	0.003	0.997	0.000
E10.4 With neurological complications	0.003	0.997	0.000
G12.2 Motor neuron disease	0.003	0.997	0.000
L95.1 Erythema elevatum diutinum	0.003	0.997	0.000
L95.0 Livedoid vasculitis	0.003	0.997	0.000
S22.20 Fracture of sternum (closed)	0.003	0.997	0.000
R25.1 Tremor, unspecified	0.003	0.997	0.000
H40.0 Glaucoma suspect	0.003	0.997	0.000
R49 Voice disturbances	0.003	0.997	0.000
R59.1 Generalised enlarged lymph nodes	0.000	0.997	0.003
S99.7 Multiple injuries of ankle and foot	0.003	0.997	0.000
U80 Agent resistant to penicillin and related antibiotics	0.000	0.997	0.003
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.003	0.997	0.000
R49.1 Aphonia	0.002	0.997	0.000
M54.16 Radiculopathy (Lumbar region)	0.002	0.998	0.000
E04.9 Non-toxic goitre, unspecified	0.002	0.998	0.000
R25.2 Cramp and spasm	0.002	0.998	0.000
M71.26 Synovial cyst of popliteal space [Baker]-Lower Leg	0.002	0.998	0.000
M53.3 Sacrococcygeal disorders, not elsewhere classified	0.000	0.998	0.002
S92.40 Fracture of great toe (closed)	0.002	0.998	0.000
D48.1 Connective and other soft tissue	0.000	0.998	0.002
G35 Multiple sclerosis	0.002	0.998	0.000
S92.51 Fracture of other toe (open)	0.002	0.998	0.000
R49.2 Hypernasality and hyponasality	0.002	0.998	0.000
S49.9 Unspecified injury of shoulder and upper arm	0.000	0.998	0.002
Z97.4 Presence of external hearing-aid	0.002	0.998	0.000
S92.5 Fracture of other toe	0.002	0.998	0.000
K55.2 Angiodysplasia of colon	0.002	0.998	0.000
R25 Abnormal involuntary movements	0.002	0.998	0.000
E34.0 Carcinoid syndrome	0.002	0.998	0.000
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle	0.002	0.998	0.000
S43.6 Sprain and strain of sternoclavicular joint	0.002	0.998	0.000
S43.3 Dislocation of other and unspecified parts of shoulder girdle	0.002	0.998	0.000
S43.2 Dislocation of sternoclavicular joint	0.002	0.998	0.000
S92.4 Fracture of great toe	0.002	0.998	0.000
S92.50 Fracture of other toe (closed)	0.002	0.998	0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract	0.002	0.998	0.000
S43.1 Dislocation of acromioclavicular joint	0.002	0.998	0.000
S43.4 Sprain and strain of shoulder joint	0.002	0.998	0.000
S90.0 Contusion of ankle	0.002	0.998	0.000
D84.9 Immunodeficiency, unspecified	0.002	0.998	0.000
M89.86 Other specified disorders of bone (Lower leg)	0.002	0.998	0.000
R25.8 Other and unspecified abnormal involuntary movements	0.002	0.998	0.000
S90 Superficial injury of ankle and foot	0.002	0.998	0.000
S90-S99 Injuries to the ankle and foot	0.002	0.998	0.000
H69.9 Eustachian tube disorder, unspecified	0.000	0.998	0.002
E34 Other endocrine disorders	0.002	0.998	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.002	0.998	0.000
S90.3 Contusion of other and unspecified parts of foot	0.002	0.998	0.000
S43.5 Sprain and strain of acromioclavicular joint	0.002	0.998	0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.002	0.998	0.000
M54.37 Sciatica (Lumbosacral region)	0.002	0.998	0.000
S12.20 Fracture of other specified cervical vertebra (closed)	0.002	0.998	0.000
S90.8 Other superficial injuries of ankle and foot	0.002	0.998	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.002	0.998	0.000
E20-E35 Disorders of other endocrine glands	0.002	0.998	0.000
M41.96 Scoliosis, unspecified (Lumbar region)	0.002	0.998	0.000
M53.39 Sacrococcygeal disorders, not elsewhere classified-Site uns	0.000	0.998	0.002
M53.37 Sacrococcygeal disorders, not elsewhere classified-Lumbosac	0.000	0.998	0.002
M53.36 Sacrococcygeal disorders, not elsewhere classified-Lumbar	0.000	0.998	0.002
M53.35 Sacrococcygeal disorders, not elsewhere classified-Thoracol	0.000	0.998	0.002
M53.34 Sacrococcygeal disorders, not elsewhere classified-Thoracic	0.000	0.998	0.002
M53.33 Sacrococcygeal disorders, not elsewhere classified-Cervicot	0.000	0.998	0.002
M53.32 Sacrococcygeal disorders, not elsewhere classified-Cervical	0.000	0.998	0.002
M53.31 Sacrococcygeal disorders, not elsewhere classified-Occipit-	0.000	0.998	0.002
M53.30 Sacrococcygeal disorders, not elsewhere classified-Mult sit	0.000	0.998	0.002
H92.0 Otalgia	0.002	0.998	0.000
I97.2 Postmastectomy lymphoedema syndrome	0.000	0.998	0.002
G12 Spinal muscular atrophy and related syndromes	0.002	0.998	0.000
S92 Fracture of foot, except ankle	0.002	0.998	0.000
S92.41 Fracture of great toe (open)	0.002	0.998	0.000
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.002	0.998	0.000
M71.38 Other bursal cyst (Other)	0.000	0.998	0.002
E34.8 Other specified endocrine disorders	0.002	0.998	0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters	0.002	0.998	0.000
K46.9 Unspecified abdominal hernia without obstruction or gangrene	0.002	0.998	0.000
D84 Other immunodeficiencies	0.002	0.998	0.000
S97 Crushing injury of ankle and foot	0.002	0.998	0.000
A63.0 Anogenital (venereal) warts	0.002	0.998	0.000
D07.1 Vulva	0.002	0.998	0.000
E23.2 Diabetes insipidus	0.002	0.998	0.000
R25.0 Abnormal head movements	0.002	0.998	0.000
U80.0 Penicillin resistant agent	0.000	0.998	0.002
D07.4 Penis	0.002	0.998	0.000
E34.3 Short stature, not elsewhere classified	0.002	0.998	0.000
G90.9 Disorder of autonomic nervous system, unspecified	0.002	0.998	0.000
A41.9 Septicaemia, unspecified	0.002	0.998	0.000
S90.7 Multiple superficial injuries of ankle and foot	0.002	0.998	0.000
S90.2 Contusion of toe(s) with damage to nail	0.002	0.998	0.000
M25.53 Pain in joint (Forearm)	0.000	0.998	0.002
D84.1 Defects in the complement system	0.002	0.998	0.000
E34.5 Androgen resistance syndrome	0.002	0.998	0.000
E34.4 Constitutional tall stature	0.002	0.998	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.002	0.998	0.000
E34.1 Other hypersecretion of intestinal hormones	0.002	0.998	0.000
S98 Traumatic amputation of ankle and foot	0.002	0.998	0.000
S95 Injury of blood vessels at ankle and foot level	0.002	0.998	0.000
S94 Injury of nerves at ankle and foot level	0.002	0.998	0.000
G11.9 Hereditary ataxia, unspecified	0.002	0.998	0.000
N18.5 Chronic kidney disease, stage 5	0.002	0.998	0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters	0.002	0.998	0.000
D07.2 Vagina	0.002	0.998	0.000
D84.8 Other specified immunodeficiencies	0.002	0.998	0.000
E87.7 Fluid overload	0.002	0.998	0.000
E31 Polyglandular dysfunction	0.002	0.998	0.000
S96.8 Injury of other muscles and tendons at ankle and foot level	0.002	0.998	0.000
U80.1 Methicillin resistant agent	0.000	0.998	0.002
S52.70 Multiple fractures of forearm (closed)	0.000	0.998	0.002
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.002	0.998	0.000
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.002	0.998	0.000
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.002	0.998	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.002	0.998	0.000
E32 Diseases of thymus	0.002	0.998	0.000
E30 Disorders of puberty, not elsewhere classified	0.002	0.998	0.000
E26 Hyperaldosteronism	0.002	0.998	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.002	0.998	0.000
S90.1 Contusion of toe(s) without damage to nail	0.002	0.998	0.000
S97.8 Crushing injury of other parts of ankle and foot	0.002	0.998	0.000
E25 Adrenogenital disorders	0.002	0.998	0.000
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.002	0.998	0.000
E26.9 Hyperaldosteronism, unspecified	0.002	0.998	0.000
G12.9 Spinal muscular atrophy, unspecified	0.001	0.998	0.000
G12.8 Other spinal muscular atrophies and related syndromes	0.001	0.998	0.000
G12.1 Other inherited spinal muscular atrophy	0.001	0.998	0.000
G12.0 Infantile spinal muscular atrophy, type I [Werdnig-Hoffman]	0.001	0.998	0.000
S92.9 Fracture of foot, unspecified	0.001	0.998	0.000
D07 Carcinoma in situ of other and unspecified genital organs	0.002	0.998	0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
H80 Otosclerosis	0.000	0.998	0.002
M13.93 Arthritis, unspecified (Forearm)	0.002	0.998	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.001	0.998	0.000
G90.8 Other disorders of autonomic nervous system	0.002	0.998	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.998	0.002
Z40.8 Other prophylactic surgery	0.002	0.998	0.000
A08.1 Acute gastro-enteropathy due to Norwalk agent	0.002	0.998	0.000
D83.9 Common variable immunodeficiency, unspecified	0.002	0.998	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.002	0.998	0.000
R25.3 Fasciculation	0.002	0.998	0.000
S97.1 Crushing injury of toe(s)	0.001	0.998	0.000
S97.0 Crushing injury of ankle	0.001	0.998	0.000
M54.18 Radiculopathy (Sacral and sacrococcygeal region)	0.000	0.998	0.001
D07.5 Prostate	0.002	0.998	0.000
S93.1 Dislocation of toe(s)	0.002	0.998	0.000
E20 Hypoparathyroidism	0.001	0.998	0.000
E31.0 Autoimmune polyglandular failure	0.001	0.998	0.000
Z45.0 Adjustment and management of cardiac pacemaker	0.002	0.998	0.000
C66 Malignant neoplasm of ureter	0.000	0.998	0.002
M54.39 Sciatica (Site unspecified)	0.002	0.998	0.000
S94.9 Injury of unspecified nerve at ankle and foot level	0.001	0.998	0.000
S94.8 Injury of other nerves at ankle and foot level	0.001	0.998	0.000
S94.7 Injury of multiple nerves at ankle and foot level	0.001	0.998	0.000
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.001	0.998	0.000
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.001	0.998	0.000
S94.1 Injury of medial plantar nerve	0.001	0.998	0.000
S94.0 Injury of lateral plantar nerve	0.001	0.998	0.000
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.001	0.998	0.000
S95.8 Injury of other blood vessels at ankle and foot level	0.001	0.998	0.000
S95.7 Injury of multiple blood vessels at ankle and foot level	0.001	0.998	0.000
S95.2 Injury of dorsal vein of foot	0.001	0.998	0.000
S95.1 Injury of plantar artery of foot	0.001	0.998	0.000
S95.0 Injury of dorsal artery of foot	0.001	0.998	0.000
S98.4 Traumatic amputation of foot, level unspecified	0.001	0.998	0.000
S98.3 Traumatic amputation of other parts of foot	0.001	0.998	0.000
S98.2 Traumatic amputation of two or more toes	0.001	0.998	0.000
S98.1 Traumatic amputation of one toe	0.001	0.998	0.000
S98.0 Traumatic amputation of foot at ankle level	0.001	0.998	0.000
M47.92 Spondylosis, unspecified (Cervical region)	0.000	0.998	0.002
E31.9 Polyglandular dysfunction, unspecified	0.001	0.998	0.000
E31.8 Other polyglandular dysfunction	0.001	0.998	0.000
E31.1 Polyglandular hyperfunction	0.001	0.998	0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.001	0.998	0.000
H26.8 Other specified cataract	0.000	0.998	0.002
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.001	0.998	0.000
E34.9 Endocrine disorder, unspecified	0.001	0.998	0.000
G90.0 Idiopathic peripheral autonomic neuropathy	0.001	0.998	0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.001	0.998	0.000
S92.2 Fracture of other tarsal bone(s)	0.001	0.998	0.000
E23 Hypofunction and other disorders of pituitary gland	0.001	0.998	0.000
G90 Disorders of autonomic nervous system	0.002	0.998	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.002	0.998	0.000
E26.8 Other hyperaldosteronism	0.001	0.999	0.000
E26.1 Secondary hyperaldosteronism	0.001	0.999	0.000
E30.9 Disorder of puberty, unspecified	0.001	0.999	0.000
E30.8 Other disorders of puberty	0.001	0.999	0.000
E30.1 Precocious puberty	0.001	0.999	0.000
E30.0 Delayed puberty	0.001	0.999	0.000
E32.9 Disease of thymus, unspecified	0.001	0.999	0.000
E32.8 Other diseases of thymus	0.001	0.999	0.000
E32.1 Abscess of thymus	0.001	0.999	0.000
E32.0 Persistent hyperplasia of thymus	0.001	0.999	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.001	0.999	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.001	0.999	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.001	0.999	0.000
G90.2 Horner's syndrome	0.001	0.999	0.000
O46.9 Antepartum haemorrhage, unspecified	0.001	0.999	0.000
S93.4 Sprain and strain of ankle	0.001	0.999	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.001	0.999	0.000
S93.5 Sprain and strain of toe(s)	0.001	0.999	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.001	0.999	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.001	0.999	0.000
E25.9 Adrenogenital disorder, unspecified	0.001	0.999	0.000
E25.8 Other adrenogenital disorders	0.001	0.999	0.000
S92.7 Multiple fractures of foot	0.001	0.999	0.000
Z95.1 Presence of aortocoronary bypass graft	0.001	0.999	0.000
S92.91 Fracture of foot, unspecified (open)	0.001	0.999	0.000
S92.90 Fracture of foot, unspecified (closed)	0.001	0.999	0.000
D07.6 Other and unspecified male genital organs	0.001	0.999	0.000
D07.3 Other and unspecified female genital organs	0.001	0.999	0.000
D07.0 Endometrium	0.001	0.999	0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body	0.001	0.999	0.000
S92.0 Fracture of calcaneus	0.001	0.999	0.000
S93.3 Dislocation of other and unspecified parts of foot	0.001	0.999	0.000
T82.1 Mechanical complication of cardiac electronic device	0.001	0.999	0.000
D83 Common variable immunodeficiency	0.001	0.999	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.001	0.999	0.000
H80.8 Other otosclerosis	0.000	0.999	0.001
H80.2 Cochlear otosclerosis	0.000	0.999	0.001
H80.1 Otosclerosis involving oval window, obliterative	0.000	0.999	0.001
H80.0 Otosclerosis involving oval window, nonobliterative	0.000	0.999	0.001
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.000	0.999	0.001
O82.9 Delivery by Caesarean section, unspecified	0.000	0.999	0.001
S46.0 Injury of tendon of the rotator cuff of shoulder	0.001	0.999	0.000
E29 Testicular dysfunction	0.001	0.999	0.000
M54.30 Sciatica (Multiple sites in spine)	0.001	0.999	0.000
E78.0 Pure hypercholesterolaemia	0.001	0.999	0.000
L65.9 Nonscarring hair loss, unspecified	0.001	0.999	0.000
S92.1 Fracture of talus	0.001	0.999	0.000
Y91.9 Alcohol involvement, not otherwise specified	0.000	0.999	0.001
Z97.3 Presence of spectacles and contact lenses	0.001	0.999	0.000
E20.8 Other hypoparathyroidism	0.001	0.999	0.000
E20.1 Pseudohypoparathyroidism	0.001	0.999	0.000
E20.0 Idiopathic hypoparathyroidism	0.001	0.999	0.000
E29.9 Testicular dysfunction, unspecified	0.001	0.999	0.000
O44.0 Placenta praevia specified as without haemorrhage	0.000	0.999	0.001
T91.3 Sequelae of injury of spinal cord	0.001	0.999	0.000
G37 Other demyelinating diseases of central nervous system	0.001	0.999	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.999	0.001
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.000	0.999	0.001
G11 Hereditary ataxia	0.001	0.999	0.000
M85.65 Other cyst of bone (Pelvic region and thigh)	0.000	0.999	0.001
D41.0 Kidney	0.001	0.999	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.001	0.999	0.000
G90.4 Autonomic dysreflexia	0.001	0.999	0.000
G90.1 Familial dysautonomia [Riley-Day]	0.001	0.999	0.000
K05.3 Chronic periodontitis	0.001	0.999	0.000
T88.3 Malignant hyperthermia due to anaesthesis	0.001	0.999	0.000
T88.1 Other complications following immunisation, not elsewhere classified	0.001	0.999	0.000
T88.0 Infection following immunisation	0.001	0.999	0.000
E24 Cushing's syndrome	0.001	0.999	0.000
M71.34 Other bursal cyst (Hand)	0.000	0.999	0.001
S92.21 Fracture of other tarsal bone(s) (open)	0.001	0.999	0.000
S93.40 Sprain of unspecified ligament of ankle	0.001	0.999	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.001	0.999	0.000
E23.1 Drug-induced hypopituitarism	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations