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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs11825709
log Bayes Factor = <0.0001
Chromosome 11   position 93,704,049  (GRCh37) Explore rs11825709 on Ensembl!
Variant rs11825709 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
T39.1 4-Aminophenol derivatives
0.000 0.982 0.018
E11.9 Without complications
0.000 0.982 0.018
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.000 0.984 0.016
E11 Non-insulin-dependent diabetes mellitus
0.000 0.986 0.014
T36-T50 Poisoning by drugs, medicaments and biological substances
0.000 0.986 0.014
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.000 0.987 0.013
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.000 0.987 0.013
T40.2 Other opioids
0.000 0.987 0.012
E11.3 With ophthalmic complications
0.000 0.988 0.012
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.000 0.988 0.012
E14.9 Without complications
0.000 0.988 0.012
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.000 0.988 0.012
E14 Unspecified diabetes mellitus
0.000 0.988 0.012
E10-E14 Diabetes mellitus
0.000 0.988 0.012
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.000 0.989 0.011
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.000 0.989 0.011
T39.4 Antirheumatics, not elsewhere classified
0.000 0.989 0.011
T39.2 Pyrazolone derivatives
0.000 0.989 0.011
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.000 0.989 0.011
T39.0 Salicylates
0.000 0.989 0.011
T42.4 Benzodiazepines
0.000 0.989 0.011
C44.6 Skin of upper limb, including shoulder
0.000 0.989 0.011
E11.8 With unspecified complications
0.000 0.989 0.011
E11.7 With multiple complications
0.000 0.989 0.011
E11.6 With other specified complications
0.000 0.989 0.011
E11.1 With ketoacidosis
0.000 0.989 0.011
E11.0 With coma
0.000 0.989 0.011
T43.0 Tricyclic and tetracyclic antidepressants
0.000 0.990 0.010
E11.2 With renal complications
0.000 0.990 0.010
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.000 0.990 0.010
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.000 0.990 0.010
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.000 0.990 0.010
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.000 0.990 0.010
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.000 0.990 0.010
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.000 0.990 0.010
T41 Poisoning by anaesthetics and therapeutic gases
0.000 0.990 0.010
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.000 0.990 0.010
T36 Poisoning by systemic antibiotics
0.000 0.990 0.010
C44.3 Skin of other and unspecified parts of face
0.000 0.990 0.010
C44 Other malignant neoplasms of skin
0.000 0.990 0.010
E11.4 With neurological complications
0.000 0.990 0.010
E11.5 With peripheral circulatory complications
0.000 0.990 0.010
T43.2 Other and unspecified antidepressants
0.000 0.990 0.010
E14.3 With ophthalmic complications
0.000 0.990 0.010
C44.2 Skin of ear and external auricular canal
0.000 0.990 0.010
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.000 0.990 0.009
T40.8 Lysergide [LSD]
0.000 0.990 0.009
T40.7 Cannabis (derivatives)
0.000 0.990 0.009
T40.6 Other and unspecified narcotics
0.000 0.990 0.009
T40.5 Cocaine
0.000 0.990 0.009
T40.4 Other synthetic narcotics
0.000 0.990 0.009
T40.3 Methadone
0.000 0.990 0.009
T40.1 Heroin
0.000 0.990 0.009
T40.0 Opium
0.000 0.990 0.009
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.000 0.991 0.009
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.000 0.991 0.009
T42.5 Mixed antiepileptics, not elsewhere classified
0.000 0.991 0.009
T42.3 Barbiturates
0.000 0.991 0.009
T42.2 Succinimides and oxazolidinediones
0.000 0.991 0.009
T42.1 Iminostilbenes
0.000 0.991 0.009
T42.0 Hydantoin derivatives
0.000 0.991 0.009
T46 Poisoning by agents primarily affecting the cardiovascular system
0.000 0.991 0.009
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.000 0.991 0.009
T43.9 Psychotropic drug, unspecified
0.000 0.991 0.009
T43.8 Other psychotropic drugs, not elsewhere classified
0.000 0.991 0.009
T43.6 Psychostimulants with abuse potential
0.000 0.991 0.009
T43.5 Other and unspecified antipsychotics and neuroleptics
0.000 0.991 0.009
T43.4 Butyrophenone and thioxanthene neuroleptics
0.000 0.991 0.009
T43.3 Phenothiazine antipsychotics and neuroleptics
0.000 0.991 0.009
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.000 0.991 0.009
E14.8 With unspecified complications
0.000 0.991 0.009
E14.7 With multiple complications
0.000 0.991 0.009
E14.6 With other specified complications
0.000 0.991 0.009
E14.5 With peripheral circulatory complications
0.000 0.991 0.009
E14.4 With neurological complications
0.000 0.991 0.009
E14.2 Withrenal complications
0.000 0.991 0.009
E14.1 With ketoacidosis
0.000 0.991 0.009
E14.0 With coma
0.000 0.991 0.009
E13 Other specified diabetes mellitus
0.000 0.991 0.008
E12 Malnutrition-related diabetes mellitus
0.000 0.991 0.008
C44.7 Skin of lower limb, including hip
0.000 0.992 0.008
C44.0 Skin of lip
0.000 0.992 0.008
C44.1 Skin of eyelid, including canthus
0.000 0.992 0.008
O70.1 Second degree perineal laceration during delivery
0.000 0.992 0.008
T50.9 Other and unspecified drugs, medicaments and biological substances
0.000 0.992 0.008
T50.8 Diagnostic agents
0.000 0.992 0.007
T50.7 Analeptics and opioid receptor antagonists
0.000 0.992 0.007
T50.6 Antidotes and chelating agents, not elsewhere classified
0.000 0.992 0.007
T50.5 Appetite depressants
0.000 0.992 0.007
T50.4 Drugs affecting uric acid metabolism
0.000 0.992 0.007
T50.3 Electrolytic, caloric and water-balance agents
0.000 0.992 0.007
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.000 0.992 0.007
T50.1 Loop [high-ceiling] diuretics
0.000 0.992 0.007
T50.0 Mineralocorticoids and their antagonists
0.000 0.992 0.007
T36.9 Systemic antibiotic, unspecified
0.000 0.992 0.007
T36.8 Other systemic antibiotics
0.000 0.992 0.007
T36.7 Antifungal antibiotics, systemically used
0.000 0.992 0.007
T36.6 Rifamycins
0.000 0.992 0.007
T36.5 Aminoglycosides
0.000 0.992 0.007
T36.4 Tetracyclines
0.000 0.992 0.007
T36.3 Macrolides
0.000 0.992 0.007
T36.2 Chloramphenicol group
0.000 0.992 0.007
T36.1 Cefalosporins and other Beta-lactam antibiotics
0.000 0.992 0.007
T36.0 Penicillins
0.000 0.992 0.007
T37.9 Systemic anti-infective and antiparasitic, unspecified
0.000 0.992 0.007
T37.8 Other specified systemic anti-infectives and antiparasitics
0.000 0.992 0.007
T37.5 Antiviral drugs
0.000 0.992 0.007
T37.4 Anthelminthics
0.000 0.992 0.007
T37.3 Other antiprotozoal drugs
0.000 0.992 0.007
T37.2 Antimalarials and drugs acting on other blood protozoa
0.000 0.992 0.007
T37.1 Antimycobacterial drugs
0.000 0.992 0.007
T37.0 Sulphonamides
0.000 0.992 0.007
T41.5 Therapeutic gases
0.000 0.992 0.007
T41.4 Anaesthetic, unspecified
0.000 0.992 0.007
T41.3 Local anaesthetics
0.000 0.992 0.007
T41.2 Other and unspecified general anaesthetics
0.000 0.992 0.007
T41.1 Intravenous anaesthetics
0.000 0.992 0.007
T41.0 Inhaled anaesthetics
0.000 0.992 0.007
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.000 0.992 0.007
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.000 0.992 0.007
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.000 0.992 0.007
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.000 0.992 0.007
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.000 0.992 0.007
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.000 0.992 0.007
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.000 0.992 0.007
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.000 0.992 0.007
T44.1 Other parasympathomimetics [cholinergics]
0.000 0.992 0.007
T44.0 Anticholinesterase agents
0.000 0.992 0.007
T45.9 Primarily systemic and haematological agent, unspecified
0.000 0.992 0.007
T45.8 Other primarily systemic and haematological agents
0.000 0.992 0.007
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.000 0.992 0.007
T45.6 Fibrinolysis-affecting drugs
0.000 0.992 0.007
T45.5 Anticoagulants
0.000 0.992 0.007
T45.4 Iron and its compounds
0.000 0.992 0.007
T45.3 Enzymes, not elsewhere classified
0.000 0.992 0.007
T45.2 Vitamins, not elsewhere classified
0.000 0.992 0.007
T45.1 Antineoplastic and immunosuppressive drugs
0.000 0.992 0.007
T45.0 Antiallergic and antiemetic drugs
0.000 0.992 0.007
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.000 0.992 0.007
T47.8 Other agents primarily affecting the gastro-intestinal system
0.000 0.992 0.007
T47.7 Emetics
0.000 0.992 0.007
T47.6 Antidiarrhoeal drugs
0.000 0.992 0.007
T47.5 Digestants
0.000 0.992 0.007
T47.4 Other laxatives
0.000 0.992 0.007
T47.3 Saline and osmotic laxatives
0.000 0.992 0.007
T47.2 Stimulant laxatives
0.000 0.992 0.007
T47.1 Other antacids and anti-gastric-secretion drugs
0.000 0.992 0.007
T47.0 Histamine H(2)-receptor antagonists
0.000 0.992 0.007
T48.7 Other and unspecified agents primarily acting on the respiratory system
0.000 0.992 0.007
T48.6 Antiasthmatics, not elsewhere classified
0.000 0.992 0.007
T48.5 Anti-common-cold drugs
0.000 0.992 0.007
T48.4 Expectorants
0.000 0.992 0.007
T48.3 Antitussives
0.000 0.992 0.007
T48.2 Other and unspecified agents primarily acting on muscles
0.000 0.992 0.007
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.000 0.992 0.007
T48.0 Oxytocic drugs
0.000 0.992 0.007
T49.9 Topical agent, unspecified
0.000 0.992 0.007
T49.8 Other topical agents
0.000 0.992 0.007
T49.7 Dental drugs, topically applied
0.000 0.992 0.007
T49.6 Otorhinolaryngological drugs and preparations
0.000 0.992 0.007
T49.5 Ophthalmological drugs and preparations
0.000 0.992 0.007
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.000 0.992 0.007
T49.3 Emollients, demulcents and protectants
0.000 0.992 0.007
T49.2 Local astringents and local detergents
0.000 0.992 0.007
T49.1 Antipruritics
0.000 0.992 0.007
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.000 0.992 0.007
C44.9 Malignant neoplasm of skin, unspecified
0.000 0.992 0.007
C44.8 Overlapping lesion of skin
0.000 0.992 0.007
E10 Insulin-dependent diabetes mellitus
0.000 0.993 0.007
C44.4 Skin of scalp and neck
0.000 0.993 0.007
O70.0 First degree perineal laceration during delivery
0.000 0.993 0.007
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.000 0.993 0.007
T46.8 Antivaricose drugs, including sclerosing agents
0.000 0.993 0.007
T46.7 Peripheral vasodilators
0.000 0.993 0.007
T46.5 Other antihypertensive drugs, not elsewhere classified
0.000 0.993 0.007
T46.4 Angiotensin-converting-enzyme inhibitors
0.000 0.993 0.007
T46.3 Coronary vasodilators, not elsewhere classified
0.000 0.993 0.007
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.000 0.993 0.007
T46.1 Calcium-channel blockers
0.000 0.993 0.007
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.000 0.993 0.007
T38.9 Other and unspecified hormone antagonists
0.000 0.993 0.007
T38.8 Other and unspecified hormones and their synthetic substitutes
0.000 0.993 0.007
T38.7 Androgens and anabolic congeners
0.000 0.993 0.007
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.000 0.993 0.007
T38.5 Other oestrogens and progestogens
0.000 0.993 0.007
T38.4 Oral contraceptives
0.000 0.993 0.007
T38.2 Antithyroid drugs
0.000 0.993 0.007
T38.1 Thyroid hormones and substitutes
0.000 0.993 0.007
T38.0 Glucocorticoids and synthetic analogues
0.000 0.993 0.007
O70 Perineal laceration during delivery
0.000 0.993 0.007
E12.9 Without complications
0.000 0.994 0.006
E12.8 With unspecified complications
0.000 0.994 0.006
E12.7 With multiple complications
0.000 0.994 0.006
E12.6 With other specified complications
0.000 0.994 0.006
E12.5 With peripheral circulatory complications
0.000 0.994 0.006
E12.4 With neurological complications
0.000 0.994 0.006
E12.3 With ophthalmic complications
0.000 0.994 0.006
E12.2 With renal complications
0.000 0.994 0.006
E12.1 With ketoacidosis
0.000 0.994 0.006
E12.0 With coma
0.000 0.994 0.006
E13.9 Without complications
0.000 0.994 0.006
E13.8 With unspecified complications
0.000 0.994 0.006
E13.7 With multiple complications
0.000 0.994 0.006
E13.6 With other specified complications
0.000 0.994 0.006
E13.5 With peripheral circulatory complications
0.000 0.994 0.006
E13.4 With neurological complications
0.000 0.994 0.006
E13.3 With ophthalmic complications
0.000 0.994 0.006
E13.2 With renal complications
0.000 0.994 0.006
E13.1 With ketoacidosis
0.000 0.994 0.006
E13.0 With coma
0.000 0.994 0.006
E10.3 With ophthalmic complications
0.000 0.994 0.006
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.000 0.994 0.006
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.000 0.994 0.006
E10.8 With unspecified complications
0.000 0.994 0.005
E10.7 With multiple complications
0.000 0.994 0.005
E10.6 With other specified complications
0.000 0.994 0.005
E10.5 With peripheral circulatory complications
0.000 0.994 0.005
E10.2 With renal complications
0.000 0.994 0.005
E10.0 With coma
0.000 0.994 0.005
E10.1 With ketoacidosis
0.000 0.995 0.005
O70.2 Third degree perineal laceration during delivery
0.000 0.995 0.005
G40.9 Epilepsy, unspecified
0.005 0.995 0.000
O70.9 Perineal laceration during delivery, unspecified
0.000 0.995 0.005
O70.3 Fourth degree perineal laceration during delivery
0.000 0.995 0.005
E78.0 Pure hypercholesterolaemia
0.000 0.995 0.005
E10.4 With neurological complications
0.000 0.995 0.004
E10.9 Without complications
0.000 0.995 0.005
G40 Epilepsy
0.004 0.996 0.000
Z53.2 Procedure not carried out because of patient's decision for other and unspecified reasons
0.004 0.996 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.004 0.996 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.004 0.996 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.996 0.004
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.003 0.996 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.997 0.003
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.003 0.997 0.000
C44.5 Skin of trunk
0.000 0.997 0.003
E70-E90 Metabolic disorders
0.000 0.997 0.003
M79.86 Other specified soft tissue disorders (Lower leg)
0.000 0.997 0.003
G40.8 Other epilepsy
0.003 0.997 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.003 0.997 0.000
G40.5 Special epileptic syndromes
0.003 0.997 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.003 0.997 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.003 0.997 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.997 0.003
E78.6 Lipoprotein deficiency
0.000 0.997 0.003
E78.4 Other hyperlipidaemia
0.000 0.997 0.003
E78.3 Hyperchylomicronaemia
0.000 0.997 0.003
E78.2 Mixed hyperlipidaemia
0.000 0.997 0.003
E78.1 Pure hyperglyceridaemia
0.000 0.997 0.003
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.997 0.003
M20.2 Hallux rigidus
0.003 0.997 0.000
E88 Other metabolic disorders
0.000 0.997 0.003
C43.6 Malignant melanoma of upper limb, including shoulder
0.003 0.997 0.000
E78.5 Hyperlipidaemia, unspecified
0.000 0.997 0.003
E83 Disorders of mineral metabolism
0.000 0.997 0.003
E00-E07 Disorders of thyroid gland
0.000 0.997 0.003
E65-E68 Obesity and other hyperalimentation
0.000 0.997 0.003
E85 Amyloidosis
0.000 0.997 0.003
E84 Cystic fibrosis
0.000 0.997 0.003
E79 Disorders of purine and pyrimidine metabolism
0.000 0.997 0.003
E77 Disorders of glycoprotein metabolism
0.000 0.997 0.003
E76 Disorders of glycosaminoglycan metabolism
0.000 0.997 0.003
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.997 0.003
E74 Other disorders of carbohydrate metabolism
0.000 0.997 0.003
E73 Lactose intolerance
0.000 0.997 0.003
E72 Other disorders of amino-acid metabolism
0.000 0.997 0.003
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.997 0.003
E70 Disorders of aromatic amino-acid metabolism
0.000 0.997 0.003
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.997 0.003
E40-E46 Malnutrition
0.000 0.997 0.002
C43-C44 Melanoma and other malignant neoplasms of skin
0.000 0.997 0.002
E86 Volume depletion
0.000 0.997 0.003
E80.4 Gilbert's syndrome
0.000 0.997 0.002
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.997 0.002
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.997 0.002
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.997 0.002
E07 Other disorders of thyroid
0.000 0.997 0.002
E83.5 Disorders of calcium metabolism
0.000 0.998 0.002
E07.9 Disorder of thyroid, unspecified
0.000 0.998 0.002
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.998 0.002
E80.6 Other disorders of bilirubin metabolism
0.000 0.998 0.002
E80.5 Crigler-Najjar syndrome
0.000 0.998 0.002
E80.3 Defects of catalase and peroxydase
0.000 0.998 0.002
E80.2 Other porphyria
0.000 0.998 0.002
E80.1 Porphyria cutanea tarda
0.000 0.998 0.002
E80.0 Hereditary erythropoietic porphyria
0.000 0.998 0.002
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.998 0.002
E78.8 Other disorders of lipoprotein metabolism
0.000 0.998 0.002
E88.9 Metabolic disorder, unspecified
0.000 0.998 0.002
E88.8 Other specified metabolic disorders
0.000 0.998 0.002
E88.3 Tumour lysis syndrome
0.000 0.998 0.002
E88.2 Lipomatosis, not elsewhere classified
0.000 0.998 0.002
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.998 0.002
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.998 0.002
E83.8 Other disorders of mineral metabolism
0.000 0.998 0.002
E83.2 Disorders of zinc metabolism
0.000 0.998 0.002
E83.0 Disorders of copper metabolism
0.000 0.998 0.002
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.998 0.002
E00 Congenital iodine-deficiency syndrome
0.000 0.998 0.002
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.998 0.002
E50-E64 Other nutritional deficiencies
0.000 0.998 0.002
E67 Other hyperalimentation
0.000 0.998 0.002
E68 Sequelae of hyperalimentation
0.000 0.998 0.002
E65 Localised adiposity
0.000 0.998 0.002
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.998 0.002
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.998 0.002
E70.3 Albinism
0.000 0.998 0.002
E70.2 Disorders of tyrosine metabolism
0.000 0.998 0.002
E70.1 Other hyperphenylalaninaemias
0.000 0.998 0.002
E70.0 Classical phenylketonuria
0.000 0.998 0.002
E71.3 Disorders of fatty-acid metabolism
0.000 0.998 0.002
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.998 0.002
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.998 0.002
E71.0 Maple-syrup-urine disease
0.000 0.998 0.002
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.998 0.002
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.998 0.002
E72.5 Disorders of glycine metabolism
0.000 0.998 0.002
E72.4 Disorders of ornithine metabolism
0.000 0.998 0.002
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.998 0.002
E72.2 Disorders of urea cycle metabolism
0.000 0.998 0.002
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.998 0.002
E72.0 Disorders of amino-acid transport
0.000 0.998 0.002
E73.9 Lactose intolerance, unspecified
0.000 0.998 0.002
E73.8 Other lactose intolerance
0.000 0.998 0.002
E73.1 Secondary lactase deficiency
0.000 0.998 0.002
E73.0 Congenital lactase deficiency
0.000 0.998 0.002
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.998 0.002
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.998 0.002
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.998 0.002
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.998 0.002
E74.2 Disorders of galactose metabolism
0.000 0.998 0.002
E74.1 Disorders of fructose metabolism
0.000 0.998 0.002
E74.0 Glycogen storage disease
0.000 0.998 0.002
E75.6 Lipid storage disorder, unspecified
0.000 0.998 0.002
E75.5 Other lipid storage disorders
0.000 0.998 0.002
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.998 0.002
E75.3 Sphingolipidosis, unspecified
0.000 0.998 0.002
E75.2 Other sphingolipidosis
0.000 0.998 0.002
E75.1 Other gangliosidosis
0.000 0.998 0.002
E75.0 GM2 gangliosidosis
0.000 0.998 0.002
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.998 0.002
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.998 0.002
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.998 0.002
E76.2 Other mucopolysaccharidoses
0.000 0.998 0.002
E76.1 Mucopolysaccharidosis, type II
0.000 0.998 0.002
E76.0 Mucopolysaccharidosis, type I
0.000 0.998 0.002
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.998 0.002
E77.8 Other disorders of glycoprotein metabolism
0.000 0.998 0.002
E77.1 Defects in glycoprotein degradation
0.000 0.998 0.002
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.998 0.002
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.998 0.002
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.998 0.002
E79.1 Lesch-Nyhan syndrome
0.000 0.998 0.002
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.998 0.002
E84.9 Cystic fibrosis, unspecified
0.000 0.998 0.002
E84.8 Cystic fibrosis with other manifestations
0.000 0.998 0.002
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.998 0.002
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.998 0.002
E85.9 Amyloidosis, unspecified
0.000 0.998 0.002
E85.8 Other amyloidosis
0.000 0.998 0.002
E85.4 Organ-limited amyloidosis
0.000 0.998 0.002
E85.3 Secondary systemic amyloidosis
0.000 0.998 0.002
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.998 0.002
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.998 0.002
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.998 0.002
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.998 0.002
E45 Retarded development following protein-energy malnutrition
0.000 0.998 0.002
E43 Unspecified severe protein-energy malnutrition
0.000 0.998 0.002
E42 Marasmic kwashiorkor
0.000 0.998 0.002
E41 Nutritional marasmus
0.000 0.998 0.002
E40 Kwashiorkor
0.000 0.998 0.002
E83.4 Disorders of magnesium metabolism
0.000 0.998 0.002
E83.3 Disorders of phosphorus metabolism
0.000 0.998 0.002
E83.1 Disorders of iron metabolism
0.000 0.998 0.002
E15 Nondiabetic hypoglycaemic coma
0.000 0.998 0.002
E66 Obesity
0.000 0.998 0.002
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.998 0.002
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.998 0.002
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.998 0.002
E89.5 Postprocedural testicular hypofunction
0.000 0.998 0.002
E89.4 Postprocedural ovarian failure
0.000 0.998 0.002
E89.3 Postprocedural hypopituitarism
0.000 0.998 0.002
E89.2 Postprocedural hypoparathyroidism
0.000 0.998 0.002
E89.1 Postprocedural hypoinsulinaemia
0.000 0.998 0.002
E07.8 Other specified disorders of thyroid
0.000 0.998 0.002
E07.1 Dyshormogenetic goitre
0.000 0.998 0.002
E07.0 Hypersecretion of calcitonin
0.000 0.998 0.002
C43 Malignant melanoma of skin
0.001 0.998 0.001
E04 Other non-toxic goitre
0.000 0.998 0.002
E46 Unspecified protein-energy malnutrition
0.000 0.998 0.002
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.998 0.002
Z30.5 Surveillance of (intra-uterine) contraceptive device
0.000 0.998 0.002
E06 Thyroiditis
0.000 0.998 0.002
E05.9 Thyrotoxicosis, unspecified
0.000 0.998 0.002
K63.5 Polyp of colon
0.000 0.998 0.002
E03 Other hypothyroidism
0.000 0.998 0.002
E05.8 Other thyrotoxicosis
0.000 0.998 0.002
E05.5 Thyroid crisis or storm
0.000 0.998 0.002
E05.4 Thyrotoxicosis factitia
0.000 0.998 0.002
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.998 0.002
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.998 0.002
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.998 0.002
N43.3 Hydrocele, unspecified
0.000 0.998 0.002
E20-E35 Disorders of other endocrine glands
0.000 0.998 0.002
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.998 0.002
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.998 0.002
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.998 0.002
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.998 0.002
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.998 0.002
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.998 0.002
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.998 0.002
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.998 0.002
E89.0 Postprocedural hypothyroidism
0.000 0.998 0.002
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.998 0.002
E63 Other nutritional deficiencies
0.000 0.998 0.002
E56 Other vitamin deficiencies
0.000 0.998 0.002
E51 Thiamine deficiency
0.000 0.998 0.002
E50 Vitamin A deficiency
0.000 0.998 0.002
E60 Dietary zinc deficiency
0.000 0.998 0.002
E59 Dietary selenium deficiency
0.000 0.998 0.002
E58 Dietary calcium deficiency
0.000 0.998 0.002
E54 Ascorbic acid deficiency
0.000 0.998 0.002
E52 Niacin deficiency [pellagra]
0.000 0.998 0.002
E67.8 Other specified hyperalimentation
0.000 0.998 0.002
E67.3 Hypervitaminosis D
0.000 0.998 0.002
E67.2 Megavitamin-B6 syndrome
0.000 0.998 0.002
E67.1 Hypercarotenaemia
0.000 0.998 0.002
E67.0 Hypervitaminosis A
0.000 0.998 0.002
E44.1 Mild protein-energy malnutrition
0.000 0.998 0.002
E44.0 Moderate protein-energy malnutrition
0.000 0.998 0.002
E16 Other disorders of pancreatic internal secretion
0.000 0.998 0.002
E61 Deficiency of other nutrient elements
0.000 0.998 0.002
E04.9 Non-toxic goitre, unspecified
0.000 0.998 0.002
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.998 0.002
E66.1 Drug-induced obesity
0.000 0.998 0.002
E66.0 Obesity due to excess calories
0.000 0.998 0.002
C43.9 Malignant melanoma of skin, unspecified
0.001 0.998 0.001
C43.8 Overlapping malignant melanoma of skin
0.001 0.998 0.001
C43.4 Malignant melanoma of scalp and neck
0.001 0.998 0.001
C43.2 Malignant melanoma of ear and external auricular canal
0.001 0.998 0.001
C43.1 Malignant melanoma of eyelid, including canthus
0.001 0.998 0.001
C43.0 Malignant melanoma of lip
0.001 0.998 0.001
E04.8 Other specified non-toxic goitre
0.000 0.998 0.002
E04.0 Non-toxic diffuse goitre
0.000 0.998 0.002
E06.9 Thyroiditis, unspecified
0.000 0.998 0.001
E06.5 Other chronic thyroiditis
0.000 0.998 0.001
E06.4 Drug-induced thyroiditis
0.000 0.998 0.001
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.998 0.001
E06.1 Subacute thyroiditis
0.000 0.998 0.001
E06.0 Acute thyroiditis
0.000 0.998 0.001
E66.9 Obesity, unspecified
0.000 0.998 0.002
C43.3 Malignant melanoma of other and unspecified parts of face
0.001 0.998 0.001
E03.8 Other specified hypothyroidism
0.000 0.998 0.002
E03.5 Myxoedema coma
0.000 0.998 0.002
E03.4 Atrophy of thyroid (acquired)
0.000 0.998 0.002
E03.3 Postinfectious hypothyroidism
0.000 0.998 0.002
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.998 0.002
E03.1 Congenital hypothyroidism without goitre
0.000 0.998 0.002
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.998 0.002
E04.2 Non-toxic multinodular goitre
0.000 0.998 0.002
S61.0 Open wound of finger(s) without damage to nail
0.000 0.998 0.002
E55 Vitamin D deficiency
0.000 0.998 0.001
C43.5 Malignant melanoma of trunk
0.001 0.998 0.000
E53 Deficiency of other B group vitamins
0.000 0.998 0.001
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.998 0.001
E34 Other endocrine disorders
0.000 0.998 0.001
E32 Diseases of thymus
0.000 0.998 0.001
E31 Polyglandular dysfunction
0.000 0.998 0.001
E30 Disorders of puberty, not elsewhere classified
0.000 0.998 0.001
E27 Other disorders of adrenal gland
0.000 0.998 0.001
E26 Hyperaldosteronism
0.000 0.998 0.001
E25 Adrenogenital disorders
0.000 0.998 0.001
E24 Cushing's syndrome
0.000 0.998 0.001
E20 Hypoparathyroidism
0.000 0.998 0.001
E50.9 Vitamin A deficiency, unspecified
0.000 0.998 0.001
E50.8 Other manifestations of vitamin A deficiency
0.000 0.998 0.001
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.998 0.001
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.998 0.001
E50.5 Vitamin A deficiency with night blindness
0.000 0.998 0.001
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.998 0.001
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.998 0.001
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.998 0.001
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.998 0.001
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.998 0.001
E51.9 Thiamine deficiency, unspecified
0.000 0.998 0.001
E51.8 Other manifestations of thiamine deficiency
0.000 0.998 0.001
E51.2 Wernicke's encephalopathy
0.000 0.998 0.001
E51.1 Beriberi
0.000 0.998 0.001
E56.9 Vitamin deficiency, unspecified
0.000 0.998 0.001
E56.8 Deficiency of other vitamins
0.000 0.998 0.001
E56.1 Deficiency of vitamin K
0.000 0.998 0.001
E56.0 Deficiency of vitamin E
0.000 0.998 0.001
E63.9 Nutritional deficiency, unspecified
0.000 0.998 0.001
E63.8 Other specified nutritional deficiencies
0.000 0.998 0.001
E63.1 Imbalance of constituents of food intake
0.000 0.998 0.001
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.998 0.001
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.998 0.001
E64.8 Sequelae of other nutritional deficiencies
0.000 0.998 0.001
E64.3 Sequelae of rickets
0.000 0.998 0.001
E64.2 Sequelae of vitamin C deficiency
0.000 0.998 0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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