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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs11876140
log Bayes Factor = 5.99029
Chromosome 18   position 44,510,156  (GRCh37) Explore rs11876140 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M50-M54 Other dorsopathies
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
M45-M49 Spondylopathies
1.000 0.000 0.000
M51 Other intervertebral disk disorders
0.999 0.001 0.000
M47 Spondylosis
0.998 0.002 0.000
M51.2 Other specified intervertebral disk displacement
0.990 0.010 0.000
M47.9 Spondylosis, unspecified
0.989 0.011 0.000
M54 Dorsalgia
0.986 0.014 0.000
M50 Cervical disk disorders
0.981 0.019 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.955 0.045 0.000
M40-M43 Deforming dorsopathies
0.950 0.050 0.000
M46 Other inflammatory spondylopathies
0.946 0.054 0.000
M47.8 Other spondylosis
0.942 0.058 0.000
M50.0 Cervical disk disorder with myelopathy
0.930 0.070 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.924 0.076 0.000
M54.3 Sciatica
0.918 0.082 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.917 0.083 0.000
M51.8 Other specified intervertebral disk disorders
0.902 0.098 0.000
M54.5 Low back pain
0.894 0.106 0.000
M47.86 Other spondylosis (Lumbar region)
0.876 0.124 0.000
M80-M85 Disorders of bone density and structure
0.876 0.124 0.000
M60-M63 Disorders of muscles
0.869 0.131 0.000
M43 Other deforming dorsopathies
0.869 0.131 0.000
M86-M90 Other osteopathies
0.864 0.136 0.000
M54.9 Dorsalgia, unspecified
0.861 0.139 0.000
M50.1 Cervical disk disorder with radiculopathy
0.859 0.141 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.858 0.142 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.850 0.150 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.847 0.153 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.841 0.159 0.000
M54.2 Cervicalgia
0.837 0.163 0.000
M84 Disorders of continuity of bone
0.837 0.163 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.834 0.166 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.833 0.167 0.000
M47.89 Other spondylosis (Site unspecified)
0.830 0.170 0.000
T42.4 Benzodiazepines
0.827 0.173 0.000
M48 Other spondylopathies
0.822 0.177 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.822 0.178 0.000
M41 Scoliosis
0.821 0.179 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.818 0.182 0.000
M47.1 Other spondylosis with myelopathy
0.817 0.183 0.000
M91-M94 Chondropathies
0.816 0.183 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.812 0.188 0.000
M50.3 Other cervical disk degeneration
0.812 0.188 0.000
M43.1 Spondylolisthesis
0.805 0.195 0.000
T39.1 4-Aminophenol derivatives
0.804 0.196 0.000
M54.56 Low back pain (Lumbar region)
0.800 0.200 0.000
M54.37 Sciatica (Lumbosacral region)
0.798 0.201 0.000
M51.4 Schmorl's nodes
0.794 0.205 0.000
Chapter V Mental and behavioural disorders
0.792 0.208 0.000
# Top node
0.792 0.208 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.792 0.208 0.000
T40.2 Other opioids
0.789 0.211 0.000
F10.2 Dependence syndrome
0.786 0.214 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.782 0.218 0.000
M84.0 Malunion of fracture
0.781 0.219 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.777 0.223 0.000
M46.3 Infection of intervertebral disk (pyogenic)
0.774 0.226 0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)
0.774 0.226 0.000
T51 Toxic effect of alcohol
0.768 0.232 0.000
M54.29 Cervicalgia-Site unspe
0.767 0.233 0.000
M46.4 Discitis, unspecified
0.767 0.233 0.000
M54.39 Sciatica (Site unspecified)
0.766 0.234 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.763 0.237 0.000
M65-M68 Disorders of synovium and tendon
0.761 0.239 0.000
Chapter VIII Diseases of the ear and mastoid process
0.755 0.245 0.000
M54.4 Lumbago with sciatica
0.753 0.247 0.000
M62 Other disorders of muscle
0.752 0.248 0.000
M54.36 Sciatica (Lumbar region)
0.746 0.254 0.000
Chapter XX External causes of morbidity and mortality
0.744 0.256 0.000
H65-H75 Diseases of middle ear and mastoid
0.741 0.259 0.000
M20-M25 Other joint disorders
0.739 0.261 0.000
M54.50 Low back pain (Multiple sites in spine)
0.734 0.266 0.000
T51.0 Ethanol
0.733 0.267 0.000
S90-S99 Injuries to the ankle and foot
0.733 0.267 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.732 0.268 0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)
0.731 0.269 0.000
M00-M03 Infectious arthropathies
0.731 0.269 0.000
M47.2 Other spondylosis with radiculopathy
0.729 0.271 0.000
M48.0 Spinal stenosis
0.726 0.274 0.000
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)
0.725 0.275 0.000
M47.94 Spondylosis, unspecified (Thoracic region)
0.723 0.277 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.723 0.277 0.000
M50.9 Cervical disk disorder, unspecified
0.722 0.278 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.718 0.282 0.000
M51.3 Other specified intervertebral disk degeneration
0.716 0.284 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.716 0.284 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.715 0.284 0.000
M54.57 Low back pain (Lumbosacral region)
0.715 0.285 0.000
M41.9 Scoliosis, unspecified
0.714 0.286 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.713 0.287 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.713 0.287 0.000
M25 Other joint disorders, not elsewhere classified
0.713 0.287 0.000
M54.59 Low back pain (Site unspecified)
0.710 0.290 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.709 0.291 0.000
H66 Suppurative and unspecified otitis media
0.709 0.291 0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)
0.709 0.291 0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)
0.709 0.291 0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)
0.709 0.291 0.000
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)
0.709 0.291 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.708 0.292 0.000
M54.8 Other dorsalgia
0.707 0.293 0.000
M54.0 Panniculitis affecting regions of neck and back
0.707 0.293 0.000
M40 Kyphosis and lordosis
0.706 0.294 0.000
M49 Spondylopathies in diseases classified elsewhere
0.704 0.295 0.000
M85 Other disorders of bone density and structure
0.704 0.296 0.000
M50.8 Other cervical disk disorders
0.703 0.297 0.000
M93 Other osteochondropathies
0.702 0.298 0.000
F30-F39 Mood [affective] disorders
0.701 0.299 0.000
M84.4 Pathological fracture, not elsewhere classified
0.698 0.302 0.000
M43.16 Spondylolisthesis (Lumbar region)
0.697 0.303 0.000
M54.6 Pain in thoracic spine
0.697 0.303 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.696 0.304 0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)
0.692 0.308 0.000
M51.9 Intervertebral disk disorder, unspecified
0.691 0.309 0.000
M89 Other disorders of bone
0.689 0.311 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.689 0.311 0.000
M47.12 Other spondylosis with myelopathy (Cervical region)
0.687 0.313 0.000
O85-O92 Complications predominantly related to the puerperium
0.683 0.317 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.682 0.318 0.000
M42 Spinal osteochondrosis
0.681 0.319 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.681 0.319 0.000
M46.8 Other specified inflammatory spondylopathies
0.678 0.321 0.000
M46.5 Other infective spondylopathies
0.678 0.321 0.000
M46.2 Osteomyelitis of vertebra
0.678 0.321 0.000
M46.1 Sacro-iliitis, not elsewhere classified
0.678 0.321 0.000
M46.0 Spinal enthesopathy
0.678 0.321 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.677 0.323 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.675 0.324 0.000
M47.84 Other spondylosis (Thoracic region)
0.675 0.324 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.675 0.324 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.675 0.324 0.000
M50.2 Other cervical disk displacement
0.675 0.325 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.673 0.327 0.000
M60 Myositis
0.672 0.328 0.000
H71 Cholesteatoma of middle ear
0.671 0.329 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.669 0.331 0.000
S80-S89 Injuries to the knee and lower leg
0.669 0.331 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.668 0.332 0.000
T20 Burn and corrosion of head and neck
0.668 0.332 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.667 0.333 0.000
W20-W49 Exposure to inanimate mechanical forces
0.666 0.334 0.000
M87 Osteonecrosis
0.665 0.335 0.000
T43.2 Other and unspecified antidepressants
0.663 0.337 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.663 0.337 0.000
M43.17 Spondylolisthesis (Lumbosacral region)
0.663 0.337 0.000
F40 Phobic anxiety disorders
0.662 0.338 0.000
T51.9 Alcohol, unspecified
0.662 0.338 0.000
O23 Infections of genito-urinary tract in pregnancy
0.659 0.341 0.000
T90 Sequelae of injuries of head
0.659 0.341 0.000
M54.35 Sciatica (Thoracolumbar region)
0.658 0.342 0.000
M54.34 Sciatica-Thoracic
0.658 0.342 0.000
M54.33 Sciatica-Cervicothoracic
0.658 0.342 0.000
M54.32 Sciatica-Cervical
0.658 0.342 0.000
M54.31 Sciatica-Occipit-atl-axl
0.658 0.342 0.000
M54.30 Sciatica (Multiple sites in spine)
0.658 0.342 0.000
M90 Osteopathies in diseases classified elsewhere
0.656 0.344 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.656 0.344 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.656 0.344 0.000
M53 Other dorsopathies, not elsewhere classified
0.654 0.346 0.000
M48.02 Spinal stenosis (Cervical region)
0.652 0.348 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.651 0.349 0.000
M46.36 Infection of intervertebral disc (pyogenic) (Lumbar region)
0.651 0.349 0.000
O86 Other puerperal infections
0.650 0.350 0.000
M43.6 Torticollis
0.650 0.350 0.000
M84.02 Malunion of fracture (Upper arm)
0.648 0.352 0.000
S32 Fracture of lumbar spine and pelvis
0.648 0.352 0.000
M25.5 Pain in joint
0.648 0.352 0.000
M62.8 Other specified disorders of muscle
0.648 0.352 0.000
M88 Paget's disease of bone [osteitis deformans]
0.646 0.353 0.000
M84.03 Malunion of fracture (Forearm)
0.645 0.355 0.000
M54.47 Lumbago with sciatica (Lumbosacral region)
0.643 0.357 0.000
T56 Toxic effect of metals
0.643 0.357 0.000
M54.92 Dorsalgia, unspecified (Cervical region)
0.642 0.357 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.642 0.358 0.000
T00-T07 Injuries involving multiple body regions
0.642 0.358 0.000
M54.54 Low back pain-Thoracic
0.641 0.359 0.000
M54.53 Low back pain-Cervicothoracic
0.641 0.359 0.000
M54.52 Low back pain-Cervical
0.641 0.359 0.000
M54.51 Low back pain-Occipit-atl-axl
0.641 0.359 0.000
M86 Osteomyelitis
0.641 0.359 0.000
M43.19 Spondylolisthesis (Site unspecified)
0.640 0.360 0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)
0.638 0.362 0.000
M46.46 Discitis, unspecified (Lumbar region)
0.638 0.362 0.000
T40.4 Other synthetic narcotics
0.636 0.364 0.000
M84.06 Malunion of fracture (Lower leg)
0.635 0.364 0.000
F10.6 Amnesic syndrome
0.635 0.365 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.634 0.366 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.634 0.366 0.000
S90 Superficial injury of ankle and foot
0.631 0.369 0.000
M25.9 Joint disorder, unspecified
0.629 0.371 0.000
H66.9 Otitis media, unspecified
0.628 0.372 0.000
M83 Adult osteomalacia
0.628 0.372 0.000
F33 Recurrent depressive disorder
0.627 0.373 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.627 0.373 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.626 0.374 0.000
M99 Biomechanical lesions, not elsewhere classified
0.625 0.375 0.000
X60-X84 Intentional self-harm
0.625 0.375 0.000
M92 Other juvenile osteochondrosis
0.624 0.376 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.623 0.377 0.000
M61 Calcification and ossification of muscle
0.623 0.377 0.000
M43.9 Deforming dorsopathy, unspecified
0.623 0.377 0.000
M43.8 Other specified deforming dorsopathies
0.623 0.377 0.000
M43.5 Other recurrent vertebral subluxation
0.623 0.377 0.000
M43.4 Other recurrent atlantoaxial subluxation
0.623 0.377 0.000
M43.3 Recurrent atlantoaxial subluxation with myelopathy
0.623 0.377 0.000
M43.2 Other fusion of spine
0.623 0.377 0.000
T90.9 Sequelae of unspecified injury of head
0.623 0.377 0.000
M43.0 Spondylolysis
0.622 0.378 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.620 0.380 0.000
M93.9 Osteochondropathy, unspecified
0.620 0.380 0.000
W25 Contact with sharp glass
0.619 0.381 0.000
Y84.8 Other medical procedures
0.618 0.382 0.000
M41.8 Other forms of scoliosis
0.618 0.382 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.617 0.382 0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)
0.617 0.382 0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)
0.617 0.382 0.000
H74 Other disorders of middle ear and mastoid
0.618 0.382 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.617 0.383 0.000
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)
0.615 0.385 0.000
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)
0.615 0.385 0.000
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)
0.615 0.385 0.000
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)
0.615 0.385 0.000
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)
0.615 0.385 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.614 0.386 0.000
T54 Toxic effect of corrosive substances
0.614 0.386 0.000
M84.07 Malunion of fracture (Ankle and foot)
0.614 0.386 0.000
O23.4 Unspecified infection of urinary tract in pregnancy
0.613 0.387 0.000
H66.1 Chronic tubotympanic suppurative otitis media
0.612 0.388 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.610 0.390 0.000
F40.2 Specific (isolated) phobias
0.609 0.391 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.609 0.391 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.607 0.392 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.607 0.392 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.607 0.392 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.607 0.392 0.000
T40.6 Other and unspecified narcotics
0.607 0.393 0.000
M45 Ankylosing spondylitis
0.606 0.394 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.606 0.394 0.000
M41.99 Scoliosis, unspecified (Site unspecified)
0.605 0.395 0.000
O86.4 Pyrexia of unknown origin following delivery
0.604 0.396 0.000
S92 Fracture of foot, except ankle
0.603 0.397 0.000
M66 Spontaneous rupture of synovium and tendon
0.602 0.398 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.601 0.398 0.000
M54.28 Cervicalgia-Sacral/sacrococ
0.600 0.400 0.000
M54.27 Cervicalgia-Lumbosacral
0.600 0.400 0.000
M54.26 Cervicalgia-Lumbar
0.600 0.400 0.000
M54.25 Cervicalgia-Thoracolumbar
0.600 0.400 0.000
M54.24 Cervicalgia-Thoracic
0.600 0.400 0.000
M54.23 Cervicalgia (Cervicothoracic region)
0.600 0.400 0.000
M54.21 Cervicalgia (Occipito-atlanto-axial region)
0.600 0.400 0.000
M54.20 Cervicalgia-Mult site
0.600 0.400 0.000
M84.9 Disorder of continuity of bone, unspecified
0.600 0.400 0.000
M84.8 Other disorders of continuity of bone
0.600 0.400 0.000
M84.3 Stress fracture, not elsewhere classified
0.600 0.400 0.000
M84.2 Delayed union of fracture
0.600 0.400 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.599 0.401 0.000
M25.3 Other instability of joint
0.599 0.401 0.000
O21 Excessive vomiting in pregnancy
0.599 0.401 0.000
H69 Other disorders of Eustachian tube
0.599 0.401 0.000
M84.48 Pathological fracture, not elsewhere classified (Other)
0.598 0.402 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.598 0.402 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.598 0.402 0.000
T42.3 Barbiturates
0.598 0.402 0.000
T42.2 Succinimides and oxazolidinediones
0.598 0.402 0.000
T42.1 Iminostilbenes
0.598 0.402 0.000
T42.0 Hydantoin derivatives
0.598 0.402 0.000
T39.4 Antirheumatics, not elsewhere classified
0.597 0.403 0.000
T39.2 Pyrazolone derivatives
0.597 0.403 0.000
M91 Juvenile osteochondrosis of hip and pelvis
0.597 0.403 0.000
W20 Struck by thrown, projected or falling object
0.596 0.404 0.000
S82 Fracture of lower leg, including ankle
0.595 0.405 0.000
T92 Sequelae of injuries of upper limb
0.595 0.405 0.000
T36 Poisoning by systemic antibiotics
0.594 0.405 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.594 0.406 0.000
O24 Diabetes mellitus in pregnancy
0.594 0.406 0.000
M34 Systemic sclerosis
0.594 0.406 0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)
0.594 0.406 0.000
F70-F79 Mental retardation
0.591 0.409 0.000
M24 Other specific joint derangements
0.591 0.409 0.000
H66.3 Other chronic suppurative otitis media
0.591 0.409 0.000
M48.9 Spondylopathy, unspecified
0.590 0.410 0.000
M48.8 Other specified spondylopathies
0.590 0.410 0.000
M48.4 Fatigue fracture of vertebra
0.590 0.410 0.000
M48.3 Traumatic spondylopathy
0.590 0.410 0.000
M48.2 Kissing spine
0.590 0.410 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.590 0.410 0.000
T33-T35 Frostbite
0.590 0.410 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.590 0.410 0.000
M21 Other acquired deformities of limbs
0.589 0.411 0.000
M41.5 Other secondary scoliosis
0.588 0.412 0.000
M41.4 Neuromuscular scoliosis
0.588 0.412 0.000
M41.3 Thoracogenic scoliosis
0.588 0.412 0.000
M41.2 Other idiopathic scoliosis
0.588 0.412 0.000
M41.1 Juvenile idiopathic scoliosis
0.588 0.412 0.000
M41.0 Infantile idiopathic scoliosis
0.588 0.412 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.587 0.413 0.000
T40.8 Lysergide [LSD]
0.587 0.413 0.000
T40.7 Cannabis (derivatives)
0.587 0.413 0.000
T40.5 Cocaine
0.587 0.413 0.000
T40.3 Methadone
0.587 0.413 0.000
T40.1 Heroin
0.587 0.413 0.000
T40.0 Opium
0.587 0.413 0.000
M43.12 Spondylolisthesis (Cervical region)
0.586 0.413 0.000
M47.19 Other spondylosis with myelopathy (Site unspecified)
0.586 0.414 0.000
M47.18 Other spondylosis with myelopathy (Sacral and sacrococcygeal region)
0.586 0.414 0.000
M47.17 Other spondylosis with myelopathy (Lumbosacral region)
0.586 0.414 0.000
M47.16 Other spondylosis with myelopathy (Lumbar region)
0.586 0.414 0.000
M47.15 Other spondylosis with myelopathy (Thoracolumbar region)
0.586 0.414 0.000
M47.14 Other spondylosis with myelopathy (Thoracic region)
0.586 0.414 0.000
M47.13 Other spondylosis with myelopathy (Cervicothoracic region)
0.586 0.414 0.000
M47.11 Other spondylosis with myelopathy (Occipito-atlanto-axial region)
0.586 0.414 0.000
M47.10 Other spondylosis with myelopathy (Multiple sites in spine)
0.586 0.414 0.000
T66-T78 Other and unspecified effects of external causes
0.586 0.414 0.000
W25.9 Unspecified place
0.585 0.415 0.000
M25.8 Other specified joint disorders
0.585 0.415 0.000
F11 Mental and behavioural disorders due to use of opioids
0.585 0.415 0.000
M80 Osteoporosis with pathological fracture
0.584 0.416 0.000
M62.1 Other rupture of muscle (nontraumatic)
0.582 0.418 0.000
T43.6 Psychostimulants with abuse potential
0.581 0.419 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.580 0.420 0.000
M54.55 Low back pain (Thoracolumbar region)
0.580 0.420 0.000
Q80-Q89 Other congenital malformations
0.579 0.421 0.000
T20.2 Burn of second degree of head and neck
0.579 0.421 0.000
M43.18 Spondylolisthesis (Sacral and sacrococcygeal region)
0.577 0.423 0.000
M43.15 Spondylolisthesis (Thoracolumbar region)
0.577 0.423 0.000
M43.14 Spondylolisthesis (Thoracic region)
0.577 0.423 0.000
M43.13 Spondylolisthesis (Cervicothoracic region)
0.577 0.423 0.000
M43.11 Spondylolisthesis (Occipito-atlanto-axial region)
0.577 0.423 0.000
M43.10 Spondylolisthesis (Multiple sites in spine)
0.577 0.423 0.000
Y00-Y09 Assault
0.575 0.424 0.000
S82.2 Fracture of shaft of tibia
0.575 0.425 0.000
T23 Burn and corrosion of wrist and hand
0.575 0.425 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.573 0.426 0.000
X50-X57 Overexertion, travel and privation
0.573 0.427 0.000
M85.6 Other cyst of bone
0.572 0.427 0.000
H70 Mastoiditis and related conditions
0.572 0.427 0.000
F99-F99 Unspecified mental disorder
0.572 0.428 0.000
V10-V19 Pedal cyclist injured in transport accident
0.572 0.428 0.000
F10.4 Withdrawal state with delirium
0.570 0.429 0.000
F00 Dementia in Alzheimer's disease
0.570 0.430 0.000
M25.96 Joint disorder, unspecified (Lower leg)
0.570 0.430 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.569 0.431 0.000
S82.20 Fracture of shaft of tibia (closed)
0.568 0.432 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.568 0.432 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.568 0.432 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.568 0.432 0.000
T65 Toxic effect of other and unspecified substances
0.568 0.432 0.000
T62 Toxic effect of other noxious substances eaten as food
0.568 0.432 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.568 0.432 0.000
T60 Toxic effect of pesticides
0.568 0.432 0.000
T57 Toxic effect of other inorganic substances
0.568 0.432 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.568 0.432 0.000
T52 Toxic effect of organic solvents
0.568 0.432 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.568 0.432 0.000
T55 Toxic effect of soaps and detergents
0.568 0.432 0.000
T59 Toxic effect of other gases, fumes and vapours
0.567 0.432 0.000
M84.01 Malunion of fracture (Shoulder region)
0.565 0.435 0.000
M25.52 Pain in joint (Upper arm)
0.564 0.436 0.000
S70-S79 Injuries to the hip and thigh
0.564 0.436 0.000
V40-V49 Car occupant injured in transport accident
0.564 0.436 0.000
H80-H83 Diseases of inner ear
0.562 0.438 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.561 0.439 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.560 0.439 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.560 0.439 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.560 0.439 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.560 0.439 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.560 0.439 0.000
M84.09 Malunion of fracture (Site unspecified)
0.560 0.440 0.000
M84.08 Malunion of fracture (Other)
0.560 0.440 0.000
M84.05 Malunion of fracture (Pelvic region and thigh)
0.560 0.440 0.000
M84.04 Malunion of fracture (Hand)
0.560 0.440 0.000
M84.00 Malunion of fracture (Multiple sites)
0.560 0.440 0.000
M85.0 Fibrous dysplasia (monostotic)
0.560 0.440 0.000
W00-W19 Falls
0.560 0.440 0.000
V80-V89 Other land transport accidents
0.559 0.441 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.559 0.441 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.559 0.441 0.000
M87.9 Osteonecrosis, unspecified
0.558 0.442 0.000
F10.8 Other mental and behavioural disorders
0.557 0.443 0.000
F10.7 Residual and late-onset psychotic disorder
0.557 0.443 0.000
S81 Open wound of lower leg
0.556 0.444 0.000
M46.39 Infection of intervertebral disc (pyogenic) (Site unspecified)
0.555 0.445 0.000
M46.38 Infection of intervertebral disc (pyogenic) (Sacral and sacrococcygeal region)
0.555 0.445 0.000
M46.37 Infection of intervertebral disc (pyogenic) (Lumbosacral region)
0.555 0.445 0.000
M46.35 Infection of intervertebral disc (pyogenic) (Thoracolumbar region)
0.555 0.445 0.000
M46.34 Infection of intervertebral disc (pyogenic) (Thoracic region)
0.555 0.445 0.000
M46.33 Infection of intervertebral disc (pyogenic) (Cervicothoracic region)
0.555 0.445 0.000
M46.32 Infection of intervertebral disc (pyogenic) (Cervical region)
0.555 0.445 0.000
M46.31 Infection of intervertebral disc (pyogenic) (Occipito-atlanto-axial region)
0.555 0.445 0.000
M46.30 Infection of intervertebral disc (pyogenic) (Multiple sites in spine)
0.555 0.445 0.000
S90.8 Other superficial injuries of ankle and foot
0.554 0.446 0.000
M33 Dermatopolymyositis
0.554 0.446 0.000
F10.5 Psychotic disorder
0.554 0.446 0.000
M48.09 Spinal stenosis (Site unspecified)
0.553 0.447 0.000
F48 Other neurotic disorders
0.553 0.447 0.000
O22 Venous complications in pregnancy
0.552 0.448 0.000
M65 Synovitis and tenosynovitis
0.552 0.448 0.000
T51.8 Other alcohols
0.551 0.449 0.000
T51.3 Fusel oil
0.551 0.449 0.000
T51.2 2-Propanol
0.551 0.449 0.000
T51.1 Methanol
0.551 0.449 0.000
M46.49 Discitis, unspecified (Site unspecified)
0.550 0.450 0.000
M46.48 Discitis, unspecified (Sacral and sacrococcygeal region)
0.550 0.450 0.000
M46.47 Discitis, unspecified (Lumbosacral region)
0.550 0.450 0.000
M46.45 Discitis, unspecified (Thoracolumbar region)
0.550 0.450 0.000
M46.44 Discitis, unspecified (Thoracic region)
0.550 0.450 0.000
M46.43 Discitis, unspecified (Cervicothoracic region)
0.550 0.450 0.000
M46.42 Discitis, unspecified (Cervical region)
0.550 0.450 0.000
M46.41 Discitis, unspecified (Occipito-atlanto-axial region)
0.550 0.450 0.000
M46.40 Discitis, unspecified (Multiple sites in spine)
0.550 0.450 0.000
F41 Other anxiety disorders
0.550 0.450 0.000
Y84.9 Medical procedure, unspecified
0.550 0.450 0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified
0.549 0.451 0.000
M25.54 Pain in joint (Hand)
0.549 0.451 0.000
S40-S49 Injuries to the shoulder and upper arm
0.549 0.451 0.000
M89.0 Algoneurodystrophy
0.548 0.452 0.000
H60-H62 Diseases of external ear
0.548 0.452 0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)
0.548 0.452 0.000
M89.3 Hypertrophy of bone
0.547 0.453 0.000
T25 Burn and corrosion of ankle and foot
0.547 0.453 0.000
Q85 Phakomatoses, not elsewhere classified
0.547 0.453 0.000
M41.94 Scoliosis, unspecified (Thoracic region)
0.547 0.453 0.000
M89.8 Other specified disorders of bone
0.546 0.454 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.545 0.454 0.000
F10.9 Unspecified mental and behavioural disorder
0.545 0.455 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.545 0.455 0.000
F60-F69 Disorders of adult personality and behaviour
0.544 0.456 0.000
T45.0 Antiallergic and antiemetic drugs
0.544 0.456 0.000
T21 Burn and corrosion of trunk
0.544 0.456 0.000
W20.8 Other specified place
0.543 0.457 0.000
S32.4 Fracture of acetabulum
0.543 0.457 0.000
F43 Reaction to severe stress, and adjustment disorders
0.542 0.458 0.000
F30 Manic episode
0.542 0.458 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.540 0.459 0.000
M54.48 Lumbago with sciatica (Sacral and sacrococcygeal region)
0.540 0.460 0.000
M54.45 Lumbago with sciatica (Thoracolumbar region)
0.540 0.460 0.000
M54.44 Lumbago with sciatica-Thoracic
0.540 0.460 0.000
M54.43 Lumbago with sciatica-Cervicothoracic
0.540 0.460 0.000
M54.42 Lumbago with sciatica-Cervical
0.540 0.460 0.000
M54.41 Lumbago with sciatica-Occipit-atl-axl
0.540 0.460 0.000
M54.40 Lumbago with sciatica (Multiple sites in spine)
0.540 0.460 0.000
M62.9 Disorder of muscle, unspecified
0.539 0.460 0.000
M62.6 Muscle strain
0.539 0.460 0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified
0.539 0.460 0.000
M62.4 Contracture of muscle
0.539 0.460 0.000
M62.3 Immobility syndrome (paraplegic)
0.539 0.460 0.000
M62.2 Ischaemic infarction of muscle
0.539 0.460 0.000
M62.0 Diastasis of muscle
0.539 0.460 0.000
M82 Osteoporosis in diseases classified elsewhere
0.539 0.461 0.000
M32 Systemic lupus erythematosus
0.539 0.461 0.000
T95 Sequelae of burns, corrosions and frostbite
0.538 0.462 0.000
M00 Pyogenic arthritis
0.537 0.462 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.537 0.463 0.000
T58 Toxic effect of carbon monoxide
0.537 0.463 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.536 0.463 0.000
T56.8 Other metals
0.536 0.464 0.000
T24.0 Burn of unspecified degree of hip and lower limb, except ankle and foot
0.534 0.466 0.000
O91 Infections of breast associated with childbirth
0.534 0.466 0.000
Y35-Y36 Legal intervention and operations of war
0.533 0.467 0.000
Y10-Y34 Event of undetermined intent
0.533 0.467 0.000
X85-X99 Assault
0.533 0.467 0.000
X30-X39 Exposure to forces of nature
0.533 0.467 0.000
X00-X09 Exposure to smoke, fire and flames
0.533 0.467 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.533 0.467 0.000
W75-W84 Other accidental threats to breathing
0.533 0.467 0.000
W65-W74 Accidental drowning and submersion
0.533 0.467 0.000
V98-V99 Other and unspecified transport accidents
0.533 0.467 0.000
V95-V97 Air and space transport accidents
0.533 0.467 0.000
V90-V94 Water transport accidents
0.533 0.467 0.000
V70-V79 Bus occupant injured in transport accident
0.533 0.467 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.533 0.467 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.533 0.467 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.533 0.467 0.000
V01-V09 Pedestrian injured in transport accident
0.533 0.467 0.000
F39 Unspecified mood [affective] disorder
0.533 0.467 0.000
M96.9 Postprocedural musculoskeletal disorder, unspecified
0.532 0.468 0.000
S32.7 Multiple fractures of lumbar spine and pelvis
0.532 0.468 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.532 0.468 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.531 0.468 0.000
H68 Eustachian salpingitis and obstruction
0.531 0.468 0.000
H67 Otitis media in diseases classified elsewhere
0.531 0.468 0.000
M60.9 Myositis, unspecified
0.531 0.469 0.000
T11 Other injuries of upper limb, level unspecified
0.530 0.470 0.000
M40.2 Other and unspecified kyphosis
0.530 0.470 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.530 0.470 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.530 0.470 0.000
M30 Polyarteritis nodosa and related conditions
0.530 0.470 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.529 0.471 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.529 0.471 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.528 0.472 0.000
T79-T79 Certain early complications of trauma
0.526 0.474 0.000
S98 Traumatic amputation of ankle and foot
0.526 0.474 0.000
S97 Crushing injury of ankle and foot
0.526 0.474 0.000
S95 Injury of blood vessels at ankle and foot level
0.526 0.474 0.000
S94 Injury of nerves at ankle and foot level
0.526 0.474 0.000
X10-X19 Contact with heat and hot substances
0.524 0.476 0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere
0.524 0.476 0.000
M02 Reactive arthropathies
0.524 0.476 0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere
0.524 0.476 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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