TreeWAS – Variant ID: rs11877878

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
J00-J06 Acute upper respiratory infections	0.419	0.581	0.000
J06 Acute upper respiratory infections of multiple and unspecified sites	0.416	0.584	0.000
J06.9 Acute upper respiratory infection, unspecified	0.415	0.585	0.000
Chapter X Diseases of the respiratory system	0.408	0.592	0.000
J02 Acute pharyngitis	0.397	0.603	0.000
J09-J18 Influenza and pneumonia	0.394	0.606	0.000
J33.0 Polyp of nasal cavity	0.385	0.615	0.000
J02.9 Acute pharyngitis, unspecified	0.382	0.618	0.000
J33 Nasal polyp	0.380	0.620	0.000
J30-J39 Other diseases of upper respiratory tract	0.378	0.622	0.000
J15 Bacterial pneumonia, not elsewhere classified	0.370	0.630	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.361	0.639	0.000
J03 Acute tonsillitis	0.355	0.645	0.000
J60-J70 Lung diseases due to external agents	0.354	0.646	0.000
J04 Acute laryngitis and tracheitis	0.351	0.649	0.000
J90-J94 Other diseases of pleura	0.346	0.654	0.000
J84 Other interstitial pulmonary diseases	0.343	0.657	0.000
J17 Pneumonia in diseases classified elsewhere	0.339	0.661	0.000
J11 Influenza, virus not identified	0.335	0.665	0.000
J10 Influenza due to identified influenza virus	0.327	0.673	0.000
J15.7 Pneumonia due to Mycoplasma pneumoniae	0.325	0.675	0.000
J95-J99 Other diseases of the respiratory system	0.318	0.682	0.000
J84.9 Interstitial pulmonary disease, unspecified	0.315	0.685	0.000
J15.2 Pneumonia due to staphylococcus	0.314	0.686	0.000
J36 Peritonsillar abscess	0.311	0.689	0.000
J03.9 Acute tonsillitis, unspecified	0.309	0.691	0.000
J94 Other pleural conditions	0.306	0.694	0.000
J33.9 Nasal polyp, unspecified	0.302	0.698	0.000
J04.0 Acute laryngitis	0.299	0.701	0.000
J06.8 Other acute upper respiratory infections of multiple sites	0.298	0.702	0.000
J06.0 Acute laryngopharyngitis	0.298	0.702	0.000
J15.6 Pneumonia due to other aerobic Gram-negative bacteria	0.298	0.702	0.000
J84.1 Other interstitial pulmonary diseases with fibrosis	0.297	0.703	0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.297	0.703	0.000
J69 Pneumonitis due to solids and liquids	0.295	0.705	0.000
J13 Pneumonia due to Streptococcus pneumoniae	0.293	0.707	0.000
J11.1 Influenza with other respiratory manifestations, virus not identified	0.292	0.708	0.000
J90 Pleural effusion, not elsewhere classified	0.291	0.709	0.000
J02.8 Acute pharyngitis due to other specified organisms	0.285	0.715	0.000
J02.0 Streptococcal pharyngitis	0.285	0.715	0.000
J39 Other diseases of upper respiratory tract	0.284	0.716	0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.283	0.717	0.000
J12 Viral pneumonia, not elsewhere classified	0.283	0.717	0.000
J09 Influenza due to certain identified influenza virus	0.283	0.717	0.000
J32 Chronic sinusitis	0.283	0.717	0.000
J64 Unspecified pneumoconiosis	0.280	0.720	0.000
J67 Hypersensitivity pneumonitis due to organic dust	0.276	0.724	0.000
J01 Acute sinusitis	0.276	0.724	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.275	0.725	0.000
J14 Pneumonia due to Haemophilus influenzae	0.274	0.726	0.000
J17.1 Pneumonia in viral diseases classified elsewhere	0.273	0.727	0.000
J33.1 Polypoid sinus degeneration	0.272	0.728	0.000
J80 Adult respiratory distress syndrome	0.272	0.728	0.000
J15.4 Pneumonia due to other streptococci	0.271	0.729	0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis	0.268	0.732	0.000
J15.9 Bacterial pneumonia, unspecified	0.265	0.735	0.000
J15.8 Other bacterial pneumonia	0.265	0.735	0.000
J15.5 Pneumonia due to Escherichia coli	0.265	0.735	0.000
J15.3 Pneumonia due to streptococcus, group B	0.265	0.735	0.000
J15.0 Pneumonia due to Klebsiella pneumoniae	0.265	0.735	0.000
J17.2 Pneumonia in mycoses	0.265	0.735	0.000
J94.8 Other specified pleural conditions	0.264	0.736	0.000
J38.2 Nodules of vocal cords	0.264	0.736	0.000
J10.0 Influenza with pneumonia, influenza virus identified	0.263	0.737	0.000
J99 Respiratory disorders in diseases classified elsewhere	0.259	0.741	0.000
J17.0 Pneumonia in bacterial diseases classified elsewhere	0.258	0.742	0.000
J10.1 Influenza with other respiratory manifestations, influenza virus identified	0.258	0.742	0.000
J04.1 Acute tracheitis	0.257	0.743	0.000
J03.8 Acute tonsillitis due to other specified organisms	0.255	0.745	0.000
J03.0 Streptococcal tonsillitis	0.255	0.745	0.000
J70 Respiratory conditions due to other external agents	0.254	0.746	0.000
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours	0.254	0.746	0.000
J66 Airway disease due to specific organic dust	0.254	0.746	0.000
J63 Pneumoconiosis due to other inorganic dusts	0.254	0.746	0.000
J62 Pneumoconiosis due to dust containing silica	0.254	0.746	0.000
J65 Pneumoconiosis associated with tuberculosis	0.254	0.746	0.000
J60 Coalworker's pneumoconiosis	0.254	0.746	0.000
J69.0 Pneumonitis due to food and vomit	0.253	0.747	0.000
J04.2 Acute laryngotracheitis	0.251	0.748	0.000
J15.1 Pneumonia due to Pseudomonas	0.249	0.750	0.000
J92 Pleural plaque	0.249	0.751	0.000
J17.3 Pneumonia in parasitic diseases	0.248	0.752	0.000
J32.0 Chronic maxillary sinusitis	0.248	0.752	0.000
J37 Chronic laryngitis and laryngotracheitis	0.246	0.753	0.000
J94.2 Haemothorax	0.246	0.754	0.000
J84.0 Alveolar and parietoalveolar conditions	0.246	0.754	0.000
J95 Postprocedural respiratory disorders, not elsewhere classified	0.246	0.754	0.000
J84.8 Other specified interstitial pulmonary diseases	0.245	0.755	0.000
J82 Pulmonary eosinophilia, not elsewhere classified	0.243	0.757	0.000
J17.8 Pneumonia in other diseases classified elsewhere	0.243	0.757	0.000
J38.5 Laryngeal spasm	0.241	0.759	0.000
J11.8 Influenza with other manifestations, virus not identified	0.240	0.760	0.000
J11.0 Influenza with pneumonia, virus not identified	0.240	0.760	0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres	0.240	0.760	0.000
J10.8 Influenza with other manifestations, influenza virus identified	0.235	0.765	0.000
J39.2 Other diseases of pharynx	0.232	0.768	0.000
J96 Respiratory failure, not elsewhere classified	0.228	0.772	0.000
J00 Acute nasopharyngitis [common cold]	0.225	0.775	0.000
J67.9 Hypersensitivity pneumonitis due to unspecified organic dust	0.220	0.779	0.000
J32.2 Chronic ethmoidal sinusitis	0.220	0.779	0.000
J38.4 Oedema of larynx	0.220	0.780	0.000
J94.9 Pleural condition, unspecified	0.219	0.780	0.000
J94.1 Fibrothorax	0.219	0.780	0.000
J94.0 Chylous effusion	0.219	0.780	0.000
J99.8 Respiratory disorders in other diseases classified elsewhere	0.217	0.783	0.000
J32.4 Chronic pansinusitis	0.216	0.784	0.000
J93 Pneumothorax	0.214	0.786	0.000
J38.6 Stenosis of larynx	0.213	0.787	0.000
J38.7 Other diseases of larynx	0.212	0.788	0.000
J69.8 Pneumonitis due to other solids and liquids	0.212	0.788	0.000
J69.1 Pneumonitis due to oils and essences	0.212	0.788	0.000
J38.1 Polyp of vocal cord and larynx	0.211	0.789	0.000
J33.8 Other polyp of sinus	0.210	0.790	0.000
J92.9 Pleural plaque without asbestos	0.205	0.795	0.000
J91 Pleural effusion in conditions classified elsewhere	0.204	0.796	0.000
J39.9 Disease of upper respiratory tract, unspecified	0.204	0.796	0.000
J39.3 Upper respiratory tract hypersensitivity reaction, site unspecified	0.204	0.796	0.000
J39.1 Other abscess of pharynx	0.204	0.796	0.000
J39.0 Retropharyngeal and parapharyngeal abscess	0.204	0.796	0.000
J12.9 Viral pneumonia, unspecified	0.203	0.797	0.000
J12.8 Other viral pneumonia	0.203	0.797	0.000
J12.3 Human metapneumovirus pneumonia	0.203	0.797	0.000
J12.2 Parainfluenza virus pneumonia	0.203	0.797	0.000
J12.1 Respiratory syncytial virus pneumonia	0.203	0.797	0.000
J12.0 Adenoviral pneumonia	0.203	0.797	0.000
J16.8 Pneumonia due to other specified infectious organisms	0.203	0.797	0.000
J16.0 Chlamydial pneumonia	0.203	0.797	0.000
J32.3 Chronic sphenoidal sinusitis	0.203	0.797	0.000
J32.1 Chronic frontal sinusitis	0.203	0.797	0.000
J34 Other disorders of nose and nasal sinuses	0.202	0.798	0.000
J85 Abscess of lung and mediastinum	0.200	0.800	0.000
J67.8 Hypersensitivity pneumonitis due to other organic dusts	0.198	0.802	0.000
J67.7 Air-conditioner and humidifier lung	0.198	0.802	0.000
J67.6 Maple-bark-stripper's lung	0.198	0.802	0.000
J67.5 Mushroom-worker's lung	0.198	0.802	0.000
J67.4 Maltworker's lung	0.198	0.802	0.000
J67.3 Suberosis	0.198	0.802	0.000
J67.2 Bird fancier's lung	0.198	0.802	0.000
J67.1 Bagassosis	0.198	0.802	0.000
J67.0 Farmer's lung	0.198	0.802	0.000
J01.8 Other acute sinusitis	0.198	0.802	0.000
J01.4 Acute pansinusitis	0.198	0.802	0.000
J01.3 Acute sphenoidal sinusitis	0.198	0.802	0.000
J01.2 Acute ethmoidal sinusitis	0.198	0.802	0.000
J01.1 Acute frontal sinusitis	0.198	0.802	0.000
J01.0 Acute maxillary sinusitis	0.198	0.802	0.000
J98 Other respiratory disorders	0.195	0.805	0.000
J05.0 Acute obstructive laryngitis [croup]	0.192	0.808	0.000
J95.8 Other postprocedural respiratory disorders	0.192	0.808	0.000
J32.8 Other chronic sinusitis	0.191	0.809	0.000
J99.0 Rheumatoid lung disease	0.186	0.814	0.000
J99.1 Respiratory disorders in other diffuse connective tissue disorders	0.186	0.814	0.000
J62.8 Pneumoconiosis due to other dust containing silica	0.182	0.818	0.000
J62.0 Pneumoconiosis due to talc dust	0.182	0.818	0.000
J63.8 Pneumoconiosis due to other specified inorganic dusts	0.182	0.818	0.000
J63.5 Stannosis	0.182	0.818	0.000
J63.4 Siderosis	0.182	0.818	0.000
J63.3 Graphite fibrosis (of lung)	0.182	0.818	0.000
J63.2 Berylliosis	0.182	0.818	0.000
J63.1 Bauxite fibrosis (of lung)	0.182	0.818	0.000
J63.0 Aluminosis (of lung)	0.182	0.818	0.000
J66.8 Airway disease due to other specific organic dusts	0.182	0.818	0.000
J66.2 Cannabinosis	0.182	0.818	0.000
J66.1 Flax-dresser's disease	0.182	0.818	0.000
J66.0 Byssinosis	0.182	0.818	0.000
J68.9 Unspecified respiratory condition due to chemicals, gases, fumes and vapours	0.182	0.818	0.000
J68.8 Other respiratory conditions due to chemicals, gases, fumes and vapours	0.182	0.818	0.000
J68.4 Chronic respiratory conditions due to chemicals, gases, fumes and vapours	0.182	0.818	0.000
J68.3 Other acute and subacute respiratory conditions due to chemicals, gases, fumes and vapours	0.182	0.818	0.000
J68.2 Upper respiratory inflammation due to chemicals, gases, fumes and vapours, not elsewhere classified	0.182	0.818	0.000
J68.1 Acute pulmonary oedema due to chemicals, gases, fumes and vapours	0.182	0.818	0.000
J68.0 Bronchitis and pneumonitis due to chemicals, gases, fumes and vapours	0.182	0.818	0.000
J70.9 Respiratory conditions due to unspecified external agent	0.182	0.818	0.000
J70.8 Respiratory conditions due to other specified external agents	0.182	0.818	0.000
J70.4 Drug-induced interstitial lung disorder, unspecified	0.182	0.818	0.000
J70.3 Chronic drug-induced interstitial lung disorders	0.182	0.818	0.000
J70.2 Acute drug-induced interstitial lung disorders	0.182	0.818	0.000
J70.1 Chronic and other pulmonary manifestations due to radiation	0.182	0.818	0.000
J70.0 Acute pulmonary manifestations due to radiation	0.182	0.818	0.000
J39.8 Other specified diseases of upper respiratory tract	0.180	0.820	0.000
J95.0 Tracheostomy malfunction	0.180	0.820	0.000
J81 Pulmonary oedema	0.178	0.822	0.000
J37.1 Chronic laryngotracheitis	0.177	0.823	0.000
J86 Pyothorax	0.177	0.823	0.000
J20-J22 Other acute lower respiratory infections	0.177	0.823	0.000
J95.9 Postprocedural respiratory disorder, unspecified	0.176	0.823	0.000
J95.5 Postprocedural subglottic stenosis	0.176	0.823	0.000
J95.4 Mendelson's syndrome	0.176	0.823	0.000
J95.3 Chronic pulmonary insufficiency following surgery	0.176	0.823	0.000
J95.2 Acute pulmonary insufficiency following nonthoracic surgery	0.176	0.823	0.000
J95.1 Acute pulmonary insufficiency following thoracic surgery	0.176	0.823	0.000
J01.9 Acute sinusitis, unspecified	0.173	0.827	0.000
J34.0 Abscess, furuncle and carbuncle of nose	0.168	0.832	0.000
J93.1 Other spontaneous pneumothorax	0.165	0.835	0.000
J98.4 Other disorders of lung	0.164	0.835	0.000
J96.9 Respiratory failure, unspecified	0.164	0.836	0.000
J96.1 Chronic respiratory failure	0.164	0.836	0.000
J96.0 Acute respiratory failure	0.164	0.836	0.000
J98.5 Diseases of mediastinum, not elsewhere classified	0.164	0.836	0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.160	0.839	0.001
J05.1 Acute epiglottitis	0.159	0.840	0.000
J38.3 Other diseases of vocal cords	0.159	0.841	0.000
J38.0 Paralysis of vocal cords and larynx	0.155	0.845	0.000
J93.0 Spontaneous tension pneumothorax	0.153	0.846	0.000
J37.0 Chronic laryngitis	0.152	0.848	0.000
J35 Chronic diseases of tonsils and adenoids	0.151	0.849	0.000
J34.1 Cyst and mucocele of nose and nasal sinus	0.150	0.850	0.000
J85.2 Abscess of lung without pneumonia	0.146	0.854	0.000
J98.6 Disorders of diaphragm	0.144	0.856	0.000
J85.3 Abscess of mediastinum	0.143	0.857	0.000
J85.1 Abscess of lung with pneumonia	0.143	0.857	0.000
J85.0 Gangrene and necrosis of lung	0.143	0.857	0.000
J98.3 Compensatory emphysema	0.140	0.860	0.000
J98.2 Interstitial emphysema	0.140	0.860	0.000
J92.0 Pleural plaque with presence of asbestos	0.139	0.861	0.000
J93.9 Pneumothorax, unspecified	0.138	0.862	0.000
J98.8 Other specified respiratory disorders	0.136	0.864	0.000
J30 Vasomotor and allergic rhinitis	0.135	0.865	0.000
J98.9 Respiratory disorder, unspecified	0.134	0.866	0.000
J34.8 Other specified disorders of nose and nasal sinuses	0.131	0.869	0.000
J21 Acute bronchiolitis	0.127	0.873	0.000
J86.0 Pyothorax with fistula	0.126	0.873	0.000
J20 Acute bronchitis	0.126	0.874	0.000
J93.8 Other pneumothorax	0.120	0.879	0.000
J96.09 Acute respiratory failure; Type unspecified	0.117	0.882	0.000
J96.01 Acute respiratory failure; Type II [hypercapnic]	0.117	0.882	0.000
J96.00 Acute respiratory failure; Type I [hypoxic]	0.117	0.882	0.000
J96.19 Chronic respiratory failure; Type unspecified	0.117	0.882	0.000
J96.11 Chronic respiratory failure; Type II [hypercapnic]	0.117	0.882	0.000
J96.10 Chronic respiratory failure; Type I [hypoxic]	0.117	0.882	0.000
J96.99 Respiratory failure, unspecified; Type unspecified	0.117	0.882	0.000
J96.91 Respiratory failure unspecified; Type II [hypercapnic]	0.117	0.882	0.000
J96.90 Respiratory failure, unspecified; Type I [hypoxic]	0.117	0.882	0.000
J31.1 Chronic nasopharyngitis	0.115	0.884	0.001
J34.2 Deviated nasal septum	0.116	0.884	0.000
J35.3 Hypertrophy of tonsils with hypertrophy of adenoids	0.108	0.891	0.000
J35.2 Hypertrophy of adenoids	0.108	0.891	0.000
J31.2 Chronic pharyngitis	0.108	0.892	0.001
J86.9 Pyothorax without fistula	0.107	0.893	0.000
J35.8 Other chronic diseases of tonsils and adenoids	0.104	0.896	0.000
J18 Pneumonia, organism unspecified	0.100	0.900	0.000
J30.2 Other seasonal allergic rhinitis	0.097	0.903	0.000
J30.0 Vasomotor rhinitis	0.097	0.903	0.000
J35.9 Chronic disease of tonsils and adenoids, unspecified	0.094	0.905	0.000
J35.1 Hypertrophy of tonsils	0.094	0.905	0.000
J98.1 Pulmonary collapse	0.094	0.906	0.000
J21.9 Acute bronchiolitis, unspecified	0.091	0.909	0.000
J21.8 Acute bronchiolitis due to other specified organisms	0.091	0.909	0.000
J21.1 Acute bronchiolitis due to human metapneumovirus	0.091	0.909	0.000
J21.0 Acute bronchiolitis due to respiratory syncytial virus	0.091	0.909	0.000
J20.8 Acute bronchitis due to other specified organisms	0.091	0.909	0.000
J20.7 Acute bronchitis due to echovirus	0.091	0.909	0.000
J20.6 Acute bronchitis due to rhinovirus	0.091	0.909	0.000
J20.5 Acute bronchitis due to respiratory syncytial virus	0.091	0.909	0.000
J20.4 Acute bronchitis due to parainfluenza virus	0.091	0.909	0.000
J20.3 Acute bronchitis due to coxsackie virus	0.091	0.909	0.000
J20.2 Acute bronchitis due to streptococcus	0.091	0.909	0.000
J20.1 Acute bronchitis due to Haemophilus influenzae	0.091	0.909	0.000
J20.0 Acute bronchitis due to Mycoplasma pneumoniae	0.091	0.909	0.000
J20.9 Acute bronchitis, unspecified	0.090	0.910	0.000
J30.3 Other allergic rhinitis	0.080	0.920	0.000
J34.3 Hypertrophy of nasal turbinates	0.077	0.923	0.000
J30.4 Allergic rhinitis, unspecified	0.077	0.923	0.000
J32.9 Chronic sinusitis, unspecified	0.077	0.923	0.000
J18.8 Other pneumonia, organism unspecified	0.072	0.928	0.000
J18.2 Hypostatic pneumonia, unspecified	0.072	0.928	0.000
J18.0 Bronchopneumonia, unspecified	0.071	0.929	0.000
J35.0 Chronic tonsillitis	0.068	0.932	0.000
J98.0 Diseases of bronchus, not elsewhere classified	0.059	0.940	0.001
J30.1 Allergic rhinitis due to pollen	0.055	0.945	0.000
J18.9 Pneumonia, unspecified	0.030	0.970	0.000
J31.0 Chronic rhinitis	0.026	0.973	0.002
J18.1 Lobar pneumonia, unspecified	0.016	0.984	0.000
J22 Unspecified acute lower respiratory infection	0.014	0.986	0.000
I08.0 Disorders of both mitral and aortic valves	0.010	0.990	0.000
I08 Multiple valve diseases	0.009	0.991	0.000
R22.4 Localised swelling, mass and lump, lower limb	0.000	0.992	0.008
O42.9 Premature rupture of membranes, unspecified	0.008	0.992	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.007	0.993	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.007	0.993	0.000
Q21.1 Atrial septal defect	0.000	0.993	0.007
M84.0 Malunion of fracture	0.007	0.993	0.000
M84 Disorders of continuity of bone	0.007	0.993	0.000
T39.1 4-Aminophenol derivatives	0.000	0.993	0.007
I08.1 Disorders of both mitral and tricuspid valves	0.007	0.993	0.000
O42 Premature rupture of membranes	0.007	0.993	0.000
J40-J47 Chronic lower respiratory diseases	0.007	0.993	0.000
I08.8 Other multiple valve diseases	0.007	0.993	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.007	0.993	0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.007	0.993	0.000
I08.9 Multiple valve disease, unspecified	0.006	0.993	0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.007	0.993	0.000
M84.03 Malunion of fracture (Forearm)	0.006	0.994	0.000
N60.4 Mammary duct ectasia	0.000	0.994	0.006
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.006	0.994	0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.006	0.994	0.000
N60.1 Diffuse cystic mastopathy	0.000	0.994	0.006
G31.8 Other specified degenerative diseases of nervous system	0.006	0.994	0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.006	0.994	0.000
M84.01 Malunion of fracture (Shoulder region)	0.006	0.994	0.000
N60 Benign mammary dysplasia	0.000	0.994	0.006
M84.04 Malunion of fracture (Hand)	0.006	0.994	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.006	0.994	0.000
O72.1 Other immediate postpartum haemorrhage	0.006	0.994	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.006	0.994	0.000
I05-I09 Chronic rheumatic heart diseases	0.006	0.994	0.000
N60.3 Fibrosclerosis of breast	0.000	0.994	0.006
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.006	0.994	0.000
M84.06 Malunion of fracture (Lower leg)	0.005	0.994	0.000
M80-M85 Disorders of bone density and structure	0.006	0.994	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.005	0.994	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.005	0.994	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.005	0.994	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.005	0.994	0.000
M84.4 Pathological fracture, not elsewhere classified	0.005	0.994	0.000
M84.09 Malunion of fracture (Site unspecified)	0.005	0.995	0.000
M84.08 Malunion of fracture (Other)	0.005	0.995	0.000
M84.07 Malunion of fracture (Ankle and foot)	0.005	0.995	0.000
M84.05 Malunion of fracture (Pelvic region and thigh)	0.005	0.995	0.000
M84.02 Malunion of fracture (Upper arm)	0.005	0.995	0.000
M84.00 Malunion of fracture (Multiple sites)	0.005	0.995	0.000
M84.9 Disorder of continuity of bone, unspecified	0.005	0.995	0.000
M84.8 Other disorders of continuity of bone	0.005	0.995	0.000
M84.3 Stress fracture, not elsewhere classified	0.005	0.995	0.000
M84.2 Delayed union of fracture	0.005	0.995	0.000
I07 Rheumatic tricuspid valve diseases	0.005	0.995	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.005	0.995	0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.005	0.995	0.000
O42.2 Premature rupture of membranes, labour delayed by therapy	0.005	0.995	0.000
J41 Simple and mucopurulent chronic bronchitis	0.005	0.995	0.000
M81 Osteoporosis without pathological fracture	0.005	0.995	0.000
M25.76 Osteophyte (Lower leg)	0.000	0.995	0.005
I07.1 Tricuspid insufficiency	0.005	0.995	0.000
M81.99 Osteoporosis, unspecified (Site unspecified)	0.005	0.995	0.000
M81.9 Osteoporosis, unspecified	0.005	0.995	0.000
G31.2 Degeneration of nervous system due to alcohol	0.005	0.995	0.000
R40.2 Coma, unspecified	0.005	0.995	0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.000	0.995	0.005
Q21 Congenital malformations of cardiac septa	0.000	0.995	0.005
M80 Osteoporosis with pathological fracture	0.005	0.995	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.995	0.005
N60.9 Benign mammary dysplasia, unspecified	0.000	0.995	0.004
M81.90 Osteoporosis, unspecified (Multiple sites)	0.005	0.995	0.000
I05 Rheumatic mitral valve diseases	0.005	0.995	0.000
N60.8 Other benign mammary dysplasias	0.000	0.995	0.005
Z48.8 Other specified surgical follow-up care	0.000	0.995	0.005
N60.2 Fibroadenosis of breast	0.000	0.995	0.004
I09 Other rheumatic heart diseases	0.004	0.996	0.000
M85 Other disorders of bone density and structure	0.004	0.996	0.000
R40.0 Somnolence	0.004	0.996	0.000
I06 Rheumatic aortic valve diseases	0.004	0.996	0.000
J42 Unspecified chronic bronchitis	0.004	0.996	0.000
M82 Osteoporosis in diseases classified elsewhere	0.004	0.996	0.000
G31.1 Senile degeneration of brain, not elsewhere classified	0.004	0.996	0.000
G31.0 Circumscribed brain atrophy	0.004	0.996	0.000
M84.48 Pathological fracture, not elsewhere classified (Other)	0.004	0.996	0.000
M83 Adult osteomalacia	0.004	0.996	0.000
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.004	0.996	0.000
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.004	0.996	0.000
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.004	0.996	0.000
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.004	0.996	0.000
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.004	0.996	0.000
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.004	0.996	0.000
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.004	0.996	0.000
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.004	0.996	0.000
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.004	0.996	0.000
J43 Emphysema	0.004	0.996	0.000
R22.2 Localised swelling, mass and lump, trunk	0.000	0.996	0.004
M84.29 Delayed union of fracture (Site unspecified)	0.004	0.996	0.000
M84.28 Delayed union of fracture (Other)	0.004	0.996	0.000
M84.27 Delayed union of fracture (Ankle and foot)	0.004	0.996	0.000
M84.26 Delayed union of fracture (Lower leg)	0.004	0.996	0.000
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.004	0.996	0.000
M84.24 Delayed union of fracture (Hand)	0.004	0.996	0.000
M84.23 Delayed union of fracture (Forearm)	0.004	0.996	0.000
M84.22 Delayed union of fracture (Upper arm)	0.004	0.996	0.000
M84.21 Delayed union of fracture (Shoulder region)	0.004	0.996	0.000
M84.20 Delayed union of fracture (Multiple sites)	0.004	0.996	0.000
M84.39 Stress fracture, not elsewhere classified (Site unspecified)	0.004	0.996	0.000
M84.38 Stress fracture, not elsewhere classified (Other)	0.004	0.996	0.000
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.004	0.996	0.000
M84.36 Stress fracture, not elsewhere classified (Lower leg)	0.004	0.996	0.000
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)	0.004	0.996	0.000
M84.34 Stress fracture, not elsewhere classified (Hand)	0.004	0.996	0.000
M84.33 Stress fracture, not elsewhere classified (Forearm)	0.004	0.996	0.000
M84.32 Stress fracture, not elsewhere classified (Upper arm)	0.004	0.996	0.000
M84.31 Stress fracture, not elsewhere classified (Shoulder region)	0.004	0.996	0.000
M84.30 Stress fracture, not elsewhere classified (Multiple sites)	0.004	0.996	0.000
M84.89 Other disorders of continuity of bone (Site unspecified)	0.004	0.996	0.000
M84.88 Other disorders of continuity of bone (Other)	0.004	0.996	0.000
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.004	0.996	0.000
M84.86 Other disorders of continuity of bone (Lower leg)	0.004	0.996	0.000
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)	0.004	0.996	0.000
M84.84 Other disorders of continuity of bone (Hand)	0.004	0.996	0.000
M84.83 Other disorders of continuity of bone (Forearm)	0.004	0.996	0.000
M84.82 Other disorders of continuity of bone (Upper arm)	0.004	0.996	0.000
M84.81 Other disorders of continuity of bone (Shoulder region)	0.004	0.996	0.000
M84.80 Other disorders of continuity of bone (Multiple sites)	0.004	0.996	0.000
M84.99 Disorder of continuity of bone, unspecified (Site unspecified)	0.004	0.996	0.000
M84.98 Disorder of continuity of bone, unspecified (Other)	0.004	0.996	0.000
M84.97 Disorder of continuity of bone, unspecified (Ankle and foot)	0.004	0.996	0.000
M84.96 Disorder of continuity of bone, unspecified (Lower leg)	0.004	0.996	0.000
M84.95 Disorder of continuity of bone, unspecified (Pelvic region and thigh)	0.004	0.996	0.000
M84.94 Disorder of continuity of bone, unspecified (Hand)	0.004	0.996	0.000
M84.93 Disorder of continuity of bone, unspecified (Forearm)	0.004	0.996	0.000
M84.92 Disorder of continuity of bone, unspecified (Upper arm)	0.004	0.996	0.000
M84.91 Disorder of continuity of bone, unspecified (Shoulder region)	0.004	0.996	0.000
M84.90 Disorder of continuity of bone, unspecified (Multiple sites)	0.004	0.996	0.000
R22.9 Localised swelling, mass and lump, unspecified	0.000	0.996	0.004
I07.9 Tricuspid valve disease, unspecified	0.004	0.996	0.000
I07.8 Other tricuspid valve diseases	0.004	0.996	0.000
I07.2 Tricuspid stenosis with insufficiency	0.004	0.996	0.000
I07.0 Tricuspid stenosis	0.004	0.996	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.996	0.004
M81.4 Drug-induced osteoporosis	0.004	0.996	0.000
J41.8 Mixed simple and mucopurulent chronic bronchitis	0.004	0.996	0.000
J41.1 Mucopurulent chronic bronchitis	0.004	0.996	0.000
J41.0 Simple chronic bronchitis	0.004	0.996	0.000
M81.8 Other osteoporosis	0.004	0.996	0.000
M81.6 Localised osteoporosis [Lequesne]	0.004	0.996	0.000
M81.5 Idiopathic osteoporosis	0.004	0.996	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.004	0.996	0.000
M81.1 Postoophorectomy osteoporosis	0.004	0.996	0.000
M81.0 Postmenopausal osteoporosis	0.004	0.996	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.004	0.996	0.000
J46 Status asthmaticus	0.004	0.996	0.000
I05.9 Mitral valve disease, unspecified	0.004	0.996	0.000
M81.2 Osteoporosis of disuse	0.004	0.996	0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.004	0.996	0.000
M81.96 Osteoporosis, unspecified (Lower leg)	0.004	0.996	0.000
M81.94 Osteoporosis, unspecified (Hand)	0.004	0.996	0.000
M81.93 Osteoporosis, unspecified (Forearm)	0.004	0.996	0.000
M81.92 Osteoporosis, unspecified (Upper arm)	0.004	0.996	0.000
M81.91 Osteoporosis, unspecified (Shoulder region)	0.004	0.996	0.000
R22.3 Localised swelling, mass and lump, upper limb	0.000	0.996	0.004
O72 Postpartum haemorrhage	0.004	0.996	0.000
R40 Somnolence, stupor and coma	0.004	0.996	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.004	0.996	0.000
N60.0 Solitary cyst of breast	0.000	0.996	0.004
C67.5 Bladder neck	0.004	0.996	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.996	0.004
T40.2 Other opioids	0.000	0.996	0.004
I05.1 Rheumatic mitral insufficiency	0.004	0.996	0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.004	0.996	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.004	0.996	0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.004	0.996	0.000
R22.7 Localised swelling, mass and lump, multiple sites	0.000	0.996	0.004
M85.6 Other cyst of bone	0.004	0.996	0.000
M89.9 Disorder of bone, unspecified	0.004	0.996	0.000
Q21.9 Congenital malformation of cardiac septum, unspecified	0.000	0.996	0.003
Q21.8 Other congenital malformations of cardiac septa	0.000	0.996	0.003
Q21.4 Aortopulmonary septal defect	0.000	0.996	0.003
Q21.3 Tetralogy of Fallot	0.000	0.996	0.003
Q21.2 Atrioventricular septal defect	0.000	0.996	0.003
M80.8 Other osteoporosis with pathological fracture	0.003	0.996	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.003	0.996	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.003	0.996	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.003	0.996	0.000
M85.8 Other specified disorders of bone density and structure	0.004	0.996	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.996	0.003
T39.4 Antirheumatics, not elsewhere classified	0.000	0.996	0.003
T39.2 Pyrazolone derivatives	0.000	0.996	0.003
J40 Bronchitis, not specified as acute or chronic	0.003	0.996	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.004	0.996	0.000
I05.8 Other mitral valve diseases	0.003	0.996	0.000
O72.2 Delayed and secondary postpartum haemorrhage	0.003	0.996	0.000
I09.9 Rheumatic heart disease, unspecified	0.003	0.996	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.003	0.996	0.000
M82.1 Osteoporosis in endocrine disorders	0.003	0.996	0.000
N61 Inflammatory disorders of breast	0.000	0.996	0.004
M89.94 Disorder of bone, unspecified (Hand)	0.003	0.996	0.000
K04.8 Radicular cyst	0.003	0.996	0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.003	0.997	0.000
C67 Malignant neoplasm of bladder	0.003	0.997	0.000
I09.8 Other specified rheumatic heart diseases	0.003	0.997	0.000
I09.2 Chronic rheumatic pericarditis	0.003	0.997	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.003	0.997	0.000
I09.0 Rheumatic myocarditis	0.003	0.997	0.000
M85.9 Disorder of bone density and structure, unspecified	0.003	0.997	0.000
M85.5 Aneurysmal bone cyst	0.003	0.997	0.000
M85.4 Solitary bone cyst	0.003	0.997	0.000
M85.3 Osteitis condensans	0.003	0.997	0.000
M85.2 Hyperostosis of skull	0.003	0.997	0.000
M85.1 Skeletal fluorosis	0.003	0.997	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.003	0.997	0.000
I06.8 Other rheumatic aortic valve diseases	0.003	0.997	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.003	0.997	0.000
I06.1 Rheumatic aortic insufficiency	0.003	0.997	0.000
I06.0 Rheumatic aortic stenosis	0.003	0.997	0.000
J43.2 Centrilobular emphysema	0.003	0.997	0.000
M82.8 Osteoporosis in other diseases classified elsewhere	0.003	0.997	0.000
M82.0 Osteoporosis in multiple myelomatosis	0.003	0.997	0.000
M82.3 Osteoporosis in diseases classified elsewhere, Forearm	0.003	0.997	0.000
Q21.0 Ventricular septal defect	0.000	0.997	0.003
M83.9 Adult osteomalacia, unspecified	0.003	0.997	0.000
M83.8 Other adult osteomalacia	0.003	0.997	0.000
M83.5 Other drug-induced osteomalacia in adults	0.003	0.997	0.000
M83.4 Aluminum bone disease	0.003	0.997	0.000
M83.3 Adult osteomalacia due to malnutrition	0.003	0.997	0.000
M83.2 Adult osteomalacia due to malabsorption	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations