TreeWAS – Variant ID: rs11887534

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E78.0 Pure hypercholesterolaemia	0.000	0.000	1.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis	1.000	0.000	0.000
K80.2 Calculus of gallbladder without cholecystitis	1.000	0.000	0.000
K80.1 Calculus of gallbladder with other cholecystitis	1.000	0.000	0.000
K80.0 Calculus of gallbladder with acute cholecystitis	1.000	0.000	0.000
K81.0 Acute cholecystitis	1.000	0.000	0.000
K82.8 Other specified diseases of gallbladder	1.000	0.000	0.000
K82.4 Cholesterolosis of gallbladder	1.000	0.000	0.000
K83.8 Other specified diseases of biliary tract	1.000	0.000	0.000
Z90.4 Acquired absence of other parts of digestive tract	1.000	0.000	0.000
K83 Other diseases of biliary tract	1.000	0.000	0.000
K82 Other diseases of gallbladder	1.000	0.000	0.000
K81 Cholecystitis	1.000	0.000	0.000
K80 Cholelithiasis	1.000	0.000	0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas	1.000	0.000	0.000
K81.9 Cholecystitis, unspecified	1.000	0.000	0.000
K81.1 Chronic cholecystitis	1.000	0.000	0.000
R10.1 Pain localised to upper abdomen	1.000	0.000	0.000
K83.1 Obstruction of bile duct	0.999	0.001	0.000
K80.4 Calculus of bile duct with cholecystitis	0.998	0.002	0.000
K82.1 Hydrops of gallbladder	0.994	0.006	0.000
I25.1 Atherosclerotic heart disease	0.000	0.008	0.992
K65-K67 Diseases of peritoneum	0.987	0.013	0.000
K66 Other disorders of peritoneum	0.986	0.014	0.000
K66.0 Peritoneal adhesions	0.986	0.014	0.000
Chapter XI Diseases of the digestive system	0.984	0.016	0.000
K40-K46 Hernia	0.976	0.024	0.000
I25 Chronic ischaemic heart disease	0.000	0.034	0.966
K43 Ventral hernia	0.966	0.034	0.000
K65 Peritonitis	0.962	0.038	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.039	0.961
E78.5 Hyperlipidaemia, unspecified	0.000	0.050	0.950
I20-I25 Ischaemic heart diseases	0.000	0.050	0.950
I20 Angina pectoris	0.000	0.050	0.950
I20.9 Angina pectoris, unspecified	0.000	0.051	0.949
K86 Other diseases of pancreas	0.942	0.058	0.000
K65.0 Acute peritonitis	0.937	0.063	0.000
K43.9 Ventral hernia without obstruction or gangrene	0.934	0.066	0.000
R94.5 Abnormal results of liver function studies	0.920	0.080	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.000	0.085	0.915
K43.0 Ventral hernia with obstruction, without gangrene	0.908	0.092	0.000
K41 Femoral hernia	0.903	0.097	0.000
K86.8 Other specified diseases of pancreas	0.899	0.101	0.000
I20.0 Unstable angina	0.000	0.102	0.898
K82.9 Disease of gallbladder, unspecified	0.887	0.113	0.000
K85 Acute pancreatitis	0.882	0.118	0.000
R10 Abdominal and pelvic pain	0.869	0.131	0.000
R10.4 Other and unspecified abdominal pain	0.865	0.135	0.000
K80.8 Other cholelithiasis	0.861	0.139	0.000
K65.8 Other peritonitis	0.852	0.148	0.000
K35-K38 Diseases of appendix	0.843	0.157	0.000
K46 Unspecified abdominal hernia	0.838	0.162	0.000
I24 Other acute ischaemic heart diseases	0.000	0.172	0.828
K82.3 Fistula of gallbladder	0.826	0.174	0.000
E78.2 Mixed hyperlipidaemia	0.000	0.180	0.820
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.819	0.181	0.000
K81.8 Other cholecystitis	0.818	0.182	0.000
K86.9 Disease of pancreas, unspecified	0.811	0.189	0.000
K82.0 Obstruction of gallbladder	0.799	0.201	0.000
K85.1 Biliary acute pancreatitis	0.784	0.216	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.230	0.770
K66.9 Disorder of peritoneum, unspecified	0.761	0.239	0.000
R94 Abnormal results of function studies	0.758	0.242	0.000
K38 Other diseases of appendix	0.754	0.245	0.000
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene	0.742	0.258	0.000
K82.2 Perforation of gallbladder	0.741	0.259	0.000
K46.9 Unspecified abdominal hernia without obstruction or gangrene	0.740	0.260	0.000
K83.0 Cholangitis	0.727	0.273	0.000
R94.4 Abnormal results of kidney function studies	0.726	0.274	0.000
K80.3 Calculus of bile duct with cholangitis	0.717	0.283	0.000
K83.5 Biliary cyst	0.717	0.283	0.000
K83.4 Spasm of sphincter of Oddi	0.717	0.283	0.000
K83.3 Fistula of bile duct	0.717	0.283	0.000
K83.2 Perforation of bile duct	0.717	0.283	0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.717	0.283	0.000
R10.0 Acute abdomen	0.716	0.284	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.290	0.710
K67 Disorders of peritoneum in infectious diseases classified elsewhere	0.708	0.292	0.000
K85.8 Other acute pancreatitis	0.704	0.296	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.000	0.301	0.699
I25.2 Old myocardial infarction	0.000	0.304	0.696
K86.3 Pseudocyst of pancreas	0.693	0.307	0.000
K43.7 Other and unspecified ventral hernia with gangrene	0.693	0.307	0.000
K43.6 Other and unspecified ventral hernia with obstruction, without gangrene	0.693	0.307	0.000
K43.5 Parastomal hernia without obstruction or gangrene	0.693	0.307	0.000
K43.4 Parastomal hernia with gangrene	0.693	0.307	0.000
K43.3 Parastomal hernia with obstruction, without gangrene	0.693	0.307	0.000
K43.2 Incisional hernia without obstruction or gangrene	0.693	0.307	0.000
K43.1 Ventral hernia with gangrene	0.693	0.307	0.000
I25.6 Silent myocardial ischaemia	0.000	0.307	0.693
E78.4 Other hyperlipidaemia	0.000	0.311	0.689
E78.3 Hyperchylomicronaemia	0.000	0.311	0.689
E78.1 Pure hyperglyceridaemia	0.000	0.311	0.689
I23 Certain current complications following acute myocardial infarction	0.000	0.319	0.681
K38.8 Other specified diseases of appendix	0.674	0.326	0.000
K45 Other abdominal hernia	0.663	0.337	0.000
K83.9 Disease of biliary tract, unspecified	0.658	0.341	0.000
K35 Acute appendicitis	0.658	0.342	0.000
K66.1 Haemoperitoneum	0.657	0.342	0.000
K36 Other appendicitis	0.654	0.346	0.000
K41.4 Unilateral or unspecified femoral hernia, with gangrene	0.647	0.353	0.000
K41.2 Bilateral femoral hernia, without obstruction or gangrene	0.647	0.353	0.000
K41.1 Bilateral femoral hernia, with gangrene	0.647	0.353	0.000
K41.0 Bilateral femoral hernia, with obstruction, without gangrene	0.647	0.353	0.000
E78.8 Other disorders of lipoprotein metabolism	0.000	0.358	0.642
K86.1 Other chronic pancreatitis	0.642	0.358	0.000
K85.3 Drug-induced acute pancreatitis	0.632	0.368	0.000
K85.2 Alcohol-induced acute pancreatitis	0.632	0.368	0.000
K85.0 Idiopathic acute pancreatitis	0.632	0.368	0.000
K66.8 Other specified disorders of peritoneum	0.628	0.372	0.000
I25.3 Aneurysm of heart	0.000	0.374	0.626
K86.0 Alcohol-induced chronic pancreatitis	0.614	0.386	0.000
R94.8 Abnormal results of function studies of other organs and systems	0.610	0.389	0.000
K46.1 Unspecified abdominal hernia with gangrene	0.601	0.399	0.000
K46.0 Unspecified abdominal hernia with obstruction, without gangrene	0.601	0.399	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.399	0.601
E78.6 Lipoprotein deficiency	0.000	0.404	0.596
I25.4 Coronary artery aneurysm	0.000	0.405	0.595
I24.1 Dressler's syndrome	0.000	0.406	0.594
K35.0 Acute appendicitis with generalised peritonitis	0.592	0.408	0.000
K38.1 Appendicular concretions	0.585	0.415	0.000
K44 Diaphragmatic hernia	0.585	0.415	0.000
K85.9 Acute pancreatitis, unspecified	0.581	0.419	0.000
K42 Umbilical hernia	0.577	0.422	0.000
I22 Subsequent myocardial infarction	0.000	0.432	0.568
I25.5 Ischaemic cardiomyopathy	0.000	0.442	0.558
R94.7 Abnormal results of other endocrine function studies	0.543	0.456	0.000
R94.6 Abnormal results of thyroid function studies	0.543	0.456	0.000
R94.2 Abnormal results of pulmonary function studies	0.543	0.456	0.000
R94.1 Abnormal results of function studies of peripheral nervous system and special senses	0.543	0.456	0.000
R94.0 Abnormal results of function studies of central nervous system	0.543	0.456	0.000
K38.9 Disease of appendix, unspecified	0.541	0.459	0.000
K38.3 Fistula of appendix	0.541	0.459	0.000
K38.2 Diverticulum of appendix	0.541	0.459	0.000
K38.0 Hyperplasia of appendix	0.541	0.459	0.000
K86.2 Cyst of pancreas	0.534	0.465	0.000
K80.36 Calculus of bile duct with acute and chronic cholangitis without obstruction	0.514	0.486	0.000
K87.1 Disorders of pancreas in diseases classified elsewhere	0.514	0.486	0.000
K87.0 Disorders of gallbladder and biliary tract in diseases classified elsewhere	0.514	0.486	0.000
K35.2 Acute appendicitis with generalized peritonitis	0.513	0.487	0.000
K67.8 Other disorders of peritoneum in infectious diseases classified elsewhere	0.507	0.492	0.000
K67.3 Tuberculous peritonitis	0.507	0.492	0.000
K67.2 Syphilitic peritonitis	0.507	0.492	0.000
K67.1 Gonococcal peritonitis	0.507	0.492	0.000
K67.0 Chlamydial peritonitis	0.507	0.492	0.000
I20.1 Angina pectoris with documented spasm	0.000	0.499	0.500
K65.9 Peritonitis, unspecified	0.494	0.506	0.000
I23.8 Other current complications following acute myocardial infarction	0.000	0.511	0.488
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.000	0.511	0.488
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.000	0.511	0.488
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.000	0.511	0.488
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.000	0.511	0.488
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.000	0.511	0.488
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.000	0.511	0.488
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.000	0.511	0.488
I20.8 Other forms of angina pectoris	0.000	0.519	0.481
K45.1 Other specified abdominal hernia with gangrene	0.475	0.524	0.000
K45.0 Other specified abdominal hernia with obstruction, without gangrene	0.475	0.524	0.000
K35.8 Acute appendicitis, other and unspecified	0.473	0.527	0.000
I24.8 Other forms of acute ischaemic heart disease	0.000	0.534	0.466
K40 Inguinal hernia	0.451	0.549	0.000
K42.9 Umbilical hernia without obstruction or gangrene	0.450	0.550	0.000
K35.3 Acute appendicitis with localized peritonitis	0.440	0.560	0.000
K45.8 Other specified abdominal hernia without obstruction or gangrene	0.439	0.561	0.000
I22.8 Subsequent myocardial infarction of other sites	0.000	0.567	0.433
K44.0 Diaphragmatic hernia with obstruction, without gangrene	0.420	0.580	0.000
K44.1 Diaphragmatic hernia with gangrene	0.419	0.581	0.000
K35.9 Acute appendicitis, unspecified	0.418	0.582	0.000
K42.1 Umbilical hernia with gangrene	0.414	0.586	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.587	0.412
K37 Unspecified appendicitis	0.403	0.597	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.622	0.378
K35.1 Acute appendicitis with peritoneal abscess	0.338	0.662	0.000
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene	0.336	0.664	0.000
K40.4 Unilateral or unspecified inguinal hernia, with gangrene	0.324	0.676	0.000
K40.1 Bilateral inguinal hernia, with gangrene	0.324	0.676	0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene	0.315	0.685	0.000
R94.3 Abnormal results of cardiovascular function studies	0.308	0.692	0.000
K44.9 Diaphragmatic hernia without obstruction or gangrene	0.303	0.697	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.715	0.285
I25.8 Other forms of chronic ischaemic heart disease	0.000	0.717	0.283
R10.2 Pelvic and perineal pain	0.266	0.734	0.000
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene	0.260	0.740	0.000
K90-K93 Other diseases of the digestive system	0.255	0.745	0.000
K50-K52 Noninfective enteritis and colitis	0.249	0.751	0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	0.000	0.762	0.238
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.216	0.784	0.000
K42.0 Umbilical hernia with obstruction, without gangrene	0.211	0.788	0.001
R93 Abnormal findings on diagnostic imaging of other body structures	0.191	0.809	0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene	0.189	0.811	0.000
K93 Disorders of other digestive organs in diseases classified elsewhere	0.183	0.817	0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum	0.173	0.827	0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.172	0.828	0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract	0.172	0.828	0.000
R92 Abnormal findings on diagnostic imaging of breast	0.157	0.843	0.000
I21 Acute myocardial infarction	0.000	0.846	0.154
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract	0.153	0.847	0.000
K91.4 Colostomy and enterostomy malfunction	0.149	0.851	0.000
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system	0.141	0.859	0.000
K91.1 Postgastric surgery syndromes	0.138	0.862	0.000
R93.6 Abnormal findings on diagnostic imaging of limbs	0.137	0.863	0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified	0.135	0.865	0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.131	0.868	0.000
K93.1 Megacolon in Chagas' disease	0.131	0.868	0.000
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.131	0.868	0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.000	0.869	0.131
R90 Abnormal findings on diagnostic imaging of central nervous system	0.128	0.872	0.000
K91.9 Postprocedural disorder of digestive system, unspecified	0.123	0.877	0.000
K91.5 Postcholecystectomy syndrome	0.123	0.877	0.000
K91.2 Postsurgical malabsorption, not elsewhere classified	0.123	0.877	0.000
Z82.3 Family history of stroke	0.000	0.877	0.123
K91.0 Vomiting following gastro-intestinal surgery	0.123	0.877	0.000
K51 Ulcerative colitis	0.122	0.878	0.000
K52 Other non-infective gastro-enteritis and colitis	0.121	0.879	0.000
I21.9 Acute myocardial infarction, unspecified	0.000	0.880	0.120
R93.4 Abnormal findings on diagnostic imaging of urinary organs	0.120	0.880	0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation	0.119	0.881	0.000
K51.5 Mucosal proctocolitis	0.113	0.887	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.890	0.110
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.891	0.109
K90 Intestinal malabsorption	0.104	0.896	0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities	0.000	0.897	0.102
K52.2 Allergic and dietetic gastro-enteritis and colitis	0.100	0.900	0.000
K51.1 Ulcerative (chronic) ileocolitis	0.098	0.902	0.000
R10.3 Pain localised to other parts of lower abdomen	0.098	0.902	0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified	0.000	0.906	0.094
Z82.1 Family history of blindness and visual loss	0.000	0.906	0.094
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue	0.000	0.906	0.094
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.089	0.911	0.000
K50 Crohn's disease [regional enteritis]	0.088	0.912	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.088	0.912	0.000
K70-K77 Diseases of liver	0.087	0.912	0.000
K52.0 Gastro-enteritis and colitis due to radiation	0.086	0.913	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.913	0.087
Z95.5 Presence of coronary angioplasty implant and graft	0.000	0.914	0.086
K52.3 Indeterminate colitis	0.084	0.916	0.000
K52.1 Toxic gastro-enteritis and colitis	0.083	0.917	0.000
K52.8 Other specified non-infective gastro-enteritis and colitis	0.082	0.918	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.918	0.082
K51.4 Pseudopolyposis of colon	0.082	0.918	0.000
R90.0 Intracranial space-occupying lesion	0.081	0.919	0.000
Z82.2 Family history of deafness and hearing loss	0.000	0.919	0.080
R90.8 Other abnormal findings on diagnostic imaging of central nervous system	0.079	0.921	0.000
K90.9 Intestinal malabsorption, unspecified	0.079	0.921	0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system	0.000	0.924	0.076
K90.8 Other intestinal malabsorption	0.074	0.925	0.000
K90.3 Pancreatic steatorrhoea	0.074	0.925	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.074	0.925	0.000
K90.1 Tropical sprue	0.074	0.925	0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures	0.074	0.926	0.000
Z95 Presence of cardiac and vascular implants and grafts	0.000	0.926	0.074
Z82.5 Family history of asthma and other chronic lower respiratory diseases	0.000	0.927	0.073
Z95.1 Presence of aortocoronary bypass graft	0.000	0.929	0.071
K91.3 Postoperative intestinal obstruction	0.070	0.929	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.069	0.931	0.000
K50.1 Crohn's disease of large intestine	0.069	0.931	0.000
Z95.0 Presence of cardiac pacemaker	0.000	0.933	0.067
K51.8 Other ulcerative colitis	0.065	0.934	0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.000	0.936	0.064
M54.39 Sciatica (Site unspecified)	0.064	0.936	0.000
K73 Chronic hepatitis, not elsewhere classified	0.064	0.936	0.000
K77 Liver disorders in diseases classified elsewhere	0.063	0.937	0.000
K71 Toxic liver disease	0.063	0.937	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.062	0.937	0.000
K51.2 Ulcerative (chronic) proctitis	0.061	0.939	0.000
K50.8 Other Crohn's disease	0.059	0.941	0.000
I21.4 Acute subendocardial myocardial infarction	0.000	0.941	0.059
N90.7 Vulvar cyst	0.056	0.944	0.000
K72 Hepatic failure, not elsewhere classified	0.053	0.947	0.001
Z95.3 Presence of xenogenic heart valve	0.000	0.950	0.050
Z95.4 Presence of other heart-valve replacement	0.000	0.953	0.047
K73.9 Chronic hepatitis, unspecified	0.047	0.953	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.046	0.954	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.046	0.954	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.046	0.954	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.046	0.954	0.000
K71.9 Toxic liver disease, unspecified	0.045	0.955	0.000
K71.8 Toxic liver disease with other disorders of liver	0.045	0.955	0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.045	0.955	0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.045	0.955	0.000
K71.5 Toxic liver disease with chronic active hepatitis	0.045	0.955	0.000
K71.4 Toxic liver disease with chronic lobular hepatitis	0.045	0.955	0.000
K71.3 Toxic liver disease with chronic persistent hepatitis	0.045	0.955	0.000
K71.2 Toxic liver disease with acute hepatitis	0.045	0.955	0.000
K71.1 Toxic liver disease with hepatic necrosis	0.045	0.955	0.000
K71.0 Toxic liver disease with cholestasis	0.045	0.955	0.000
K77.8 Liver disorders in other diseases classified elsewhere	0.045	0.955	0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.045	0.955	0.000
Z95.2 Presence of prosthetic heart valve	0.000	0.956	0.044
K75 Other inflammatory liver diseases	0.043	0.957	0.000
K50.0 Crohn's disease of small intestine	0.043	0.957	0.000
K72.0 Acute and subacute hepatic failure	0.042	0.957	0.000
K92 Other diseases of digestive system	0.040	0.960	0.000
E70-E90 Metabolic disorders	0.000	0.960	0.040
N90 Other noninflammatory disorders of vulva and perineum	0.039	0.961	0.000
K72.1 Chronic hepatic failure	0.038	0.961	0.001
K76 Other diseases of liver	0.038	0.962	0.000
M54.3 Sciatica	0.036	0.964	0.000
K76.9 Liver disease, unspecified	0.035	0.965	0.000
K92.9 Disease of digestive system, unspecified	0.035	0.965	0.000
K74 Fibrosis and cirrhosis of liver	0.034	0.966	0.000
N90.5 Atrophy of vulva	0.034	0.966	0.000
N90.4 Leukoplakia of vulva	0.033	0.967	0.000
K51.9 Ulcerative colitis, unspecified	0.033	0.967	0.000
K75.9 Inflammatory liver disease, unspecified	0.032	0.968	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.031	0.969	0.000
K75.2 Nonspecific reactive hepatitis	0.031	0.969	0.000
K75.1 Phlebitis of portal vein	0.031	0.969	0.000
K75.8 Other specified inflammatory liver diseases	0.031	0.969	0.000
K92.8 Other specified diseases of digestive system	0.031	0.969	0.000
E83 Disorders of mineral metabolism	0.000	0.969	0.031
N90.6 Hypertrophy of vulva	0.029	0.971	0.000
E84 Cystic fibrosis	0.000	0.971	0.029
E79 Disorders of purine and pyrimidine metabolism	0.000	0.971	0.029
E77 Disorders of glycoprotein metabolism	0.000	0.971	0.029
E76 Disorders of glycosaminoglycan metabolism	0.000	0.971	0.029
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.971	0.029
E74 Other disorders of carbohydrate metabolism	0.000	0.971	0.029
E72 Other disorders of amino-acid metabolism	0.000	0.971	0.029
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.971	0.029
E70 Disorders of aromatic amino-acid metabolism	0.000	0.971	0.029
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.971	0.029
K55-K64 Other diseases of intestines	0.029	0.971	0.000
E73 Lactose intolerance	0.000	0.971	0.028
N90.3 Dysplasia of vulva, unspecified	0.028	0.972	0.000
N90.2 Severe vulvar dysplasia, not elsewhere classified	0.028	0.972	0.000
N90.1 Moderate vulvar dysplasia	0.028	0.972	0.000
N90.0 Mild vulvar dysplasia	0.028	0.972	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.972	0.028
K56 Paralytic ileus and intestinal obstruction without hernia	0.028	0.972	0.000
K76.5 Hepatic veno-occlusive disease	0.027	0.972	0.000
K76.4 Peliosis hepatis	0.027	0.972	0.000
K76.3 Infarction of liver	0.027	0.972	0.000
K76.2 Central haemorrhagic necrosis of liver	0.027	0.972	0.000
K76.1 Chronic passive congestion of liver	0.027	0.972	0.000
N90.8 Other specified noninflammatory disorders of vulva and perineum	0.027	0.973	0.000
K75.4 Autoimmune hepatitis	0.027	0.973	0.000
K56.5 Intestinal adhesions [bands] with obstruction	0.027	0.973	0.000
E88 Other metabolic disorders	0.000	0.973	0.027
K76.7 Hepatorenal syndrome	0.027	0.973	0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.027	0.973	0.000
N90.9 Noninflammatory disorder of vulva and perineum, unspecified	0.026	0.973	0.000
M54.37 Sciatica (Lumbosacral region)	0.026	0.973	0.000
M54.36 Sciatica (Lumbar region)	0.026	0.974	0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)	0.026	0.974	0.000
M54.35 Sciatica (Thoracolumbar region)	0.026	0.974	0.000
M54.34 Sciatica-Thoracic	0.026	0.974	0.000
M54.33 Sciatica-Cervicothoracic	0.026	0.974	0.000
M54.32 Sciatica-Cervical	0.026	0.974	0.000
M54.31 Sciatica-Occipit-atl-axl	0.026	0.974	0.000
M54.30 Sciatica (Multiple sites in spine)	0.026	0.974	0.000
K70 Alcoholic liver disease	0.025	0.974	0.001
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.974	0.026
K56.6 Other and unspecified intestinal obstruction	0.025	0.975	0.000
E83.5 Disorders of calcium metabolism	0.000	0.975	0.025
K74.4 Secondary biliary cirrhosis	0.024	0.975	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.024	0.975	0.000
K74.1 Hepatic sclerosis	0.024	0.975	0.000
K74.0 Hepatic fibrosis	0.025	0.975	0.000
E83.4 Disorders of magnesium metabolism	0.000	0.975	0.025
E85 Amyloidosis	0.000	0.975	0.024
Z95.8 Presence of other cardiac and vascular implants and grafts	0.000	0.976	0.024
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.976	0.024
K74.5 Biliary cirrhosis, unspecified	0.023	0.977	0.000
K56.0 Paralytic ileus	0.023	0.977	0.000
K56.3 Gallstone ileus	0.022	0.977	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.978	0.022
E83.8 Other disorders of mineral metabolism	0.000	0.978	0.022
E83.2 Disorders of zinc metabolism	0.000	0.978	0.022
E83.0 Disorders of copper metabolism	0.000	0.978	0.022
K12 Stomatitis and related lesions	0.021	0.979	0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.979	0.021
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.979	0.021
E70.3 Albinism	0.000	0.979	0.021
E70.2 Disorders of tyrosine metabolism	0.000	0.979	0.021
E70.1 Other hyperphenylalaninaemias	0.000	0.979	0.021
E70.0 Classical phenylketonuria	0.000	0.979	0.021
E71.3 Disorders of fatty-acid metabolism	0.000	0.979	0.021
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.979	0.021
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.979	0.021
E71.0 Maple-syrup-urine disease	0.000	0.979	0.021
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.979	0.021
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.979	0.021
E72.5 Disorders of glycine metabolism	0.000	0.979	0.021
E72.4 Disorders of ornithine metabolism	0.000	0.979	0.021
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.979	0.021
E72.2 Disorders of urea cycle metabolism	0.000	0.979	0.021
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.979	0.021
E72.0 Disorders of amino-acid transport	0.000	0.979	0.021
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.979	0.021
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.979	0.021
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.979	0.021
E74.3 Other disorders of intestinal carbohydrate absorption	0.000	0.979	0.021
E74.2 Disorders of galactose metabolism	0.000	0.979	0.021
E74.1 Disorders of fructose metabolism	0.000	0.979	0.021
E74.0 Glycogen storage disease	0.000	0.979	0.021
E75.6 Lipid storage disorder, unspecified	0.000	0.979	0.021
E75.5 Other lipid storage disorders	0.000	0.979	0.021
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.979	0.021
E75.3 Sphingolipidosis, unspecified	0.000	0.979	0.021
E75.2 Other sphingolipidosis	0.000	0.979	0.021
E75.1 Other gangliosidosis	0.000	0.979	0.021
E75.0 GM2 gangliosidosis	0.000	0.979	0.021
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.979	0.021
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.979	0.021
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.979	0.021
E76.2 Other mucopolysaccharidoses	0.000	0.979	0.021
E76.1 Mucopolysaccharidosis, type II	0.000	0.979	0.021
E76.0 Mucopolysaccharidosis, type I	0.000	0.979	0.021
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.979	0.021
E77.8 Other disorders of glycoprotein metabolism	0.000	0.979	0.021
E77.1 Defects in glycoprotein degradation	0.000	0.979	0.021
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.979	0.021
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.979	0.021
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.979	0.021
E79.1 Lesch-Nyhan syndrome	0.000	0.979	0.021
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.979	0.021
E84.9 Cystic fibrosis, unspecified	0.000	0.979	0.021
E84.8 Cystic fibrosis with other manifestations	0.000	0.979	0.021
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.979	0.021
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.979	0.021
K64 Haemorrhoids and perianal venous thrombosis	0.021	0.979	0.000
E83.1 Disorders of iron metabolism	0.000	0.979	0.021
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.979	0.021
E73.8 Other lactose intolerance	0.000	0.979	0.020
E73.1 Secondary lactase deficiency	0.000	0.979	0.020
E73.0 Congenital lactase deficiency	0.000	0.979	0.020
R91 Abnormal findings on diagnostic imaging of lung	0.020	0.979	0.000
E80.7 Disorder of bilirubin metabolism, unspecified	0.000	0.979	0.020
E80.6 Other disorders of bilirubin metabolism	0.000	0.979	0.020
E80.5 Crigler-Najjar syndrome	0.000	0.979	0.020
E80.3 Defects of catalase and peroxydase	0.000	0.979	0.020
E80.2 Other porphyria	0.000	0.979	0.020
E80.1 Porphyria cutanea tarda	0.000	0.979	0.020
E80.0 Hereditary erythropoietic porphyria	0.000	0.979	0.020
K56.1 Intussusception	0.020	0.980	0.000
E73.9 Lactose intolerance, unspecified	0.000	0.980	0.020
K50.9 Crohn's disease, unspecified	0.020	0.980	0.000
E88.9 Metabolic disorder, unspecified	0.000	0.980	0.019
E88.8 Other specified metabolic disorders	0.000	0.980	0.019
E88.3 Tumour lysis syndrome	0.000	0.980	0.019
E88.1 Lipodystrophy, not elsewhere classified	0.000	0.980	0.019
K72.9 Hepatic failure, unspecified	0.019	0.980	0.001
E80.4 Gilbert's syndrome	0.000	0.980	0.019
K03 Other diseases of hard tissues of teeth	0.019	0.980	0.000
K10 Other diseases of jaws	0.019	0.981	0.000
E89.3 Postprocedural hypopituitarism	0.000	0.981	0.019
K13 Other diseases of lip and oral mucosa	0.019	0.981	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.018	0.981	0.001
E83.3 Disorders of phosphorus metabolism	0.000	0.981	0.019
K07 Dentofacial anomalies [including malocclusion]	0.018	0.982	0.000
K70.0 Alcoholic fatty liver	0.018	0.982	0.000
K00 Disorders of tooth development and eruption	0.018	0.982	0.000
K75.0 Abscess of liver	0.017	0.982	0.001
K05 Gingivitis and periodontal diseases	0.018	0.982	0.000
E89.2 Postprocedural hypoparathyroidism	0.000	0.982	0.018
K70.3 Alcoholic cirrhosis of liver	0.018	0.982	0.000
E85.8 Other amyloidosis	0.000	0.982	0.018
E85.3 Secondary systemic amyloidosis	0.000	0.982	0.018
E85.2 Heredofamilial amyloidosis, unspecified	0.000	0.982	0.018
E85.1 Neuropathic heredofamilial amyloidosis	0.000	0.982	0.018
E85.0 Nonneuropathic heredofamilial amyloidosis	0.000	0.982	0.018
K01 Embedded and impacted teeth	0.018	0.982	0.000
K04.7 Periapical abscess without sinus	0.018	0.982	0.000
K04 Diseases of pulp and periapical tissues	0.018	0.982	0.000
K63 Other diseases of intestine	0.018	0.982	0.000
K76.6 Portal hypertension	0.017	0.982	0.000
K59 Other functional intestinal disorders	0.017	0.983	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.983	0.017
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.983	0.017
E89.5 Postprocedural testicular hypofunction	0.000	0.983	0.017
E89.4 Postprocedural ovarian failure	0.000	0.983	0.017
E89.1 Postprocedural hypoinsulinaemia	0.000	0.983	0.017
K52.9 Non-infective gastro-enteritis and colitis, unspecified	0.017	0.983	0.000
K12.3 Oral mucositis (ulcerative)	0.017	0.983	0.000
K12.0 Recurrent oral aphthae	0.017	0.983	0.000
K74.3 Primary biliary cirrhosis	0.017	0.983	0.001
K63.2 Fistula of intestine	0.017	0.983	0.000
K70.4 Alcoholic hepatic failure	0.016	0.983	0.001
K14 Diseases of tongue	0.017	0.983	0.000
K59.3 Megacolon, not elsewhere classified	0.017	0.983	0.000
K74.6 Other and unspecified cirrhosis of liver	0.016	0.984	0.000
Z90 Acquired absence of organs, not elsewhere classified	0.016	0.984	0.000
E85.4 Organ-limited amyloidosis	0.000	0.984	0.016
I50.0 Congestive heart failure	0.000	0.984	0.016
M79.67 Pain in limb (Ankle and foot)	0.016	0.984	0.000
K13.6 Irritative hyperplasia of oral mucosa	0.016	0.984	0.000
I50 Heart failure	0.000	0.984	0.016
K56.4 Other impaction of intestine	0.016	0.984	0.000
K10.2 Inflammatory conditions of jaws	0.016	0.984	0.000
Chapter IX Diseases of the circulatory system	0.000	0.984	0.016
K06 Other disorders of gingiva and edentulous alveolar ridge	0.015	0.984	0.000
E88.2 Lipomatosis, not elsewhere classified	0.000	0.984	0.015
K13.4 Granuloma and granuloma-like lesions of oral mucosa	0.016	0.984	0.000
K12.1 Other forms of stomatitis	0.015	0.984	0.000
E85.9 Amyloidosis, unspecified	0.000	0.985	0.015
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.985	0.015
K64.9 Haemorrhoids, unspecified	0.015	0.985	0.000
K64.8 Other specified haemorrhoids	0.015	0.985	0.000
K64.5 Perianal venous thrombosis	0.015	0.985	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations