TreeWAS – Variant ID: rs12105421

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.572	0.428
S40-S49 Injuries to the shoulder and upper arm	0.551	0.449
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.532	0.468
S42 Fracture of shoulder and upper arm	0.530	0.470
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.520	0.480
S60-S69 Injuries to the wrist and hand	0.520	0.480
M05-M14 Inflammatory polyarthropathies	0.517	0.483
Chapter XX External causes of morbidity and mortality	0.516	0.484
M13 Other arthritis	0.512	0.488
W00-W19 Falls	0.508	0.492
M13.9 Arthritis, unspecified	0.504	0.496
# Top node	0.503	0.497
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.503	0.497
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.501	0.499
M65-M68 Disorders of synovium and tendon	0.498	0.502
M13.99 Arthritis, unspecified (Site unspecified)	0.495	0.505
S42.2 Fracture of upper end of humerus	0.493	0.507
S66 Injury of muscle and tendon at wrist and hand level	0.488	0.512
S70-S79 Injuries to the hip and thigh	0.483	0.517
S80-S89 Injuries to the knee and lower leg	0.475	0.525
M65 Synovitis and tenosynovitis	0.474	0.526
T79-T79 Certain early complications of trauma	0.474	0.526
T93 Sequelae of injuries of lower limb	0.474	0.526
I25.9 Chronic ischaemic heart disease, unspecified	0.474	0.526
T15-T19 Effects of foreign body entering through natural orifice	0.472	0.528
S50-S59 Injuries to the elbow and forearm	0.471	0.529
W18 Other fall on same level	0.470	0.530
S42.20 Fracture of upper end of humerus (closed)	0.466	0.534
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.464	0.536
S41 Open wound of shoulder and upper arm	0.458	0.542
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.456	0.544
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.453	0.547
M60-M63 Disorders of muscles	0.452	0.548
S62 Fracture at wrist and hand level	0.451	0.549
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.449	0.551
M10 Gout	0.448	0.552
W19 Unspecified fall	0.447	0.553
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.447	0.553
M65.3 Trigger finger	0.445	0.555
M13.0 Polyarthritis, unspecified	0.444	0.556
S10-S19 Injuries to the neck	0.444	0.556
S30 Superficial injury of abdomen, lower back and pelvis	0.441	0.559
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.437	0.563
W20-W49 Exposure to inanimate mechanical forces	0.436	0.564
T20-T25 Burns and corrosions of external body surface, specified by site	0.436	0.564
S40 Superficial injury of shoulder and upper arm	0.432	0.568
S72 Fracture of femur	0.429	0.571
W06 Fall involving bed	0.428	0.572
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.427	0.572
I25 Chronic ischaemic heart disease	0.427	0.573
T91 Sequelae of injuries of neck and trunk	0.427	0.573
S90-S99 Injuries to the ankle and foot	0.427	0.573
M80-M85 Disorders of bone density and structure	0.427	0.573
S20-S29 Injuries to the thorax	0.426	0.574
M91-M94 Chondropathies	0.426	0.574
S42.0 Fracture of clavicle	0.425	0.575
S42.7 Multiple fractures of clavicle, scapula and humerus	0.425	0.575
M65.34 Trigger finger-Hand	0.424	0.576
W19.4 Street and highway	0.420	0.580
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.419	0.581
M13.97 Arthritis, unspecified (Ankle and foot)	0.418	0.582
Chapter IX Diseases of the circulatory system	0.418	0.582
S42.3 Fracture of shaft of humerus	0.418	0.582
W11 Fall on and from ladder	0.417	0.583
Q20-Q28 Congenital malformations of the circulatory system	0.417	0.583
I25.2 Old myocardial infarction	0.416	0.584
I20-I25 Ischaemic heart diseases	0.414	0.586
W18.3 Sports and athletics area	0.411	0.589
T33-T35 Frostbite	0.410	0.590
T26-T28 Burns and corrosions confined to eye and internal organs	0.410	0.590
T00-T07 Injuries involving multiple body regions	0.410	0.590
Y52 Agents primarily affecting the cardiovascular system	0.410	0.590
Y51 Drugs primarily affecting the autonomic nervous system	0.409	0.591
W18.5 Trade and service area	0.408	0.592
T36-T50 Poisoning by drugs, medicaments and biological substances	0.408	0.592
M13.93 Arthritis, unspecified (Forearm)	0.404	0.596
T79 Certain early complications of trauma, not elsewhere classified	0.404	0.596
M62 Other disorders of muscle	0.403	0.597
M45-M49 Spondylopathies	0.402	0.598
M67 Other disorders of synovium and tendon	0.401	0.599
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.401	0.599
T92 Sequelae of injuries of upper limb	0.401	0.599
I10-I15 Hypertensive diseases	0.401	0.599
Y85 Sequelae of transport accidents	0.400	0.600
S49 Other and unspecified injuries of shoulder and upper arm	0.399	0.600
M10.9 Gout, unspecified	0.399	0.601
T90 Sequelae of injuries of head	0.398	0.602
V20-V29 Motorcycle rider injured in transport accident	0.397	0.603
X58-X59 Accidental exposure to other and unspecified factors	0.397	0.603
X20-X29 Contact with venomous animals and plants	0.397	0.603
Y49 Psychotropic drugs, not elsewhere classified	0.396	0.604
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.396	0.604
T93.2 Sequelae of other fractures of lower limb	0.396	0.604
S48 Traumatic amputation of shoulder and upper arm	0.395	0.605
S45 Injury of blood vessels at shoulder and upper arm level	0.395	0.605
S44 Injury of nerves at shoulder and upper arm level	0.395	0.605
S47 Crushing injury of shoulder and upper arm	0.395	0.605
I10 Essential (primary) hypertension	0.395	0.605
Y48 Anaesthetics and therapeutic gases	0.395	0.605
M11 Other crystal arthropathies	0.394	0.606
W17 Other fall from one level to another	0.393	0.607
S60 Superficial injury of wrist and hand	0.392	0.608
T94 Sequelae of injuries involving multiple and unspecified body regions	0.392	0.608
T66-T78 Other and unspecified effects of external causes	0.391	0.609
M86-M90 Other osteopathies	0.391	0.609
W10 Fall on and from stairs and steps	0.389	0.611
Chapter XXII Codes for special purposes	0.388	0.612
S66.8 Injury of other muscles and tendons at wrist and hand level	0.388	0.612
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.388	0.612
Q60-Q64 Congenital malformations of the urinary system	0.388	0.612
S42.9 Fracture of shoulder girdle, part unspecified	0.387	0.613
T17 Foreign body in respiratory tract	0.386	0.613
Y43 Primarily systemic agents	0.386	0.613
M70-M79 Other soft tissue disorders	0.386	0.614
S32 Fracture of lumbar spine and pelvis	0.386	0.614
S72.0 Fracture of neck of femur	0.385	0.615
S46 Injury of muscle and tendon at shoulder and upper arm level	0.385	0.615
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.385	0.615
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.384	0.616
V40-V49 Car occupant injured in transport accident	0.384	0.616
M13.98 Arthritis, unspecified (Other)	0.383	0.617
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.383	0.617
M13.96 Arthritis, unspecified (Lower leg)	0.382	0.618
S42.1 Fracture of scapula	0.381	0.619
T98 Sequelae of other and unspecified effects of external causes	0.381	0.619
T95 Sequelae of burns, corrosions and frostbite	0.381	0.619
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.381	0.619
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.381	0.619
M05 Seropositive rheumatoid arthritis	0.381	0.619
S42.8 Fracture of other parts of shoulder and upper arm	0.380	0.620
I95-I99 Other and unspecified disorders of the circulatory system	0.380	0.620
W50-W64 Exposure to animate mechanical forces	0.380	0.620
W29 Contact with other powered hand tools and household machinery	0.380	0.620
Y60-Y69 Misadventures to patients during surgical and medical care	0.379	0.620
M13.00 Polyarthritis, unspecified (Multiple sites)	0.378	0.622
S50 Superficial injury of forearm	0.378	0.622
S68 Traumatic amputation of wrist and hand	0.376	0.624
S83.2 Tear of meniscus, current	0.375	0.625
M00-M03 Infectious arthropathies	0.373	0.627
S65 Injury of blood vessels at wrist and hand level	0.373	0.627
S67 Crushing injury of wrist and hand	0.372	0.627
M79 Other soft tissue disorders, not elsewhere classified	0.372	0.628
V80-V89 Other land transport accidents	0.371	0.629
W19.2 School, other institution and public administrative area	0.371	0.629
M14 Arthropathies in other diseases classified elsewhere	0.370	0.629
M12 Other specific arthropathies	0.370	0.629
M09 Juvenile arthritis in diseases classified elsewhere	0.370	0.629
M08 Juvenile arthritis	0.370	0.629
T16 Foreign body in ear	0.370	0.630
Y35-Y36 Legal intervention and operations of war	0.370	0.630
Y10-Y34 Event of undetermined intent	0.370	0.630
Y00-Y09 Assault	0.370	0.630
X85-X99 Assault	0.370	0.630
X50-X57 Overexertion, travel and privation	0.370	0.630
X30-X39 Exposure to forces of nature	0.370	0.630
X10-X19 Contact with heat and hot substances	0.370	0.630
X00-X09 Exposure to smoke, fire and flames	0.370	0.630
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.370	0.630
W75-W84 Other accidental threats to breathing	0.370	0.630
W65-W74 Accidental drowning and submersion	0.370	0.630
V98-V99 Other and unspecified transport accidents	0.370	0.630
V95-V97 Air and space transport accidents	0.370	0.630
V90-V94 Water transport accidents	0.370	0.630
V70-V79 Bus occupant injured in transport accident	0.370	0.630
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.370	0.630
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.370	0.630
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.370	0.630
V01-V09 Pedestrian injured in transport accident	0.370	0.630
T79.6 Traumatic ischaemia of muscle	0.370	0.630
M13.94 Arthritis, unspecified (Hand)	0.370	0.630
W06.0 Home	0.370	0.630
S62.3 Fracture of other metacarpal bone	0.370	0.630
S64 Injury of nerves at wrist and hand level	0.370	0.630
Q21 Congenital malformations of cardiac septa	0.370	0.630
X40-X49 Accidental poisoning by and exposure to noxious substances	0.369	0.631
M62.8 Other specified disorders of muscle	0.368	0.632
M65.1 Other infective (teno)synovitis	0.368	0.632
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.367	0.632
M13.8 Other specified arthritis	0.367	0.632
M13.1 Monoarthritis, not elsewhere classified	0.367	0.632
W08 Fall involving other furniture	0.366	0.634
S41.0 Open wound of shoulder	0.366	0.634
T13 Other injuries of lower limb, level unspecified	0.365	0.635
W16 Diving or jumping into water causing injury other than drowning or submersion	0.364	0.635
W15 Fall from cliff	0.364	0.635
W14 Fall from tree	0.364	0.635
W12 Fall on and from scaffolding	0.364	0.635
W09 Fall involving playground equipment	0.364	0.635
W05 Fall involving wheelchair	0.364	0.635
W04 Fall while being carried or supported by other persons	0.364	0.635
W03 Other fall on same level due to collision with, or pushing by, another person	0.364	0.635
W01 Fall on same level from slipping, tripping and stumbling	0.364	0.635
W00 Fall on same level involving ice and snow	0.364	0.635
S41.1 Open wound of upper arm	0.364	0.636
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.363	0.637
S30.0 Contusion of lower back and pelvis	0.363	0.637
M66 Spontaneous rupture of synovium and tendon	0.362	0.638
M13.91 Arthritis, unspecified (Shoulder region)	0.362	0.638
T93.1 Sequelae of fracture of femur	0.362	0.638
M13.92 Arthritis, unspecified (Upper arm)	0.361	0.638
M65.9 Synovitis and tenosynovitis, unspecified	0.361	0.639
Chapter XVI Certain conditions originating in the perinatal period	0.361	0.639
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.360	0.639
S37 Injury of urinary and pelvic organs	0.360	0.639
S36 Injury of intra-abdominal organs	0.360	0.639
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.360	0.639
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.360	0.639
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.360	0.639
S31 Open wound of abdomen, lower back and pelvis	0.360	0.639
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.360	0.640
Y57 Other and unspecified drugs and medicaments	0.360	0.640
Y59 Other and unspecified vaccines and biological substances	0.359	0.641
Y58 Bacterial vaccines	0.359	0.641
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.359	0.641
Y53 Agents primarily affecting the gastro-intestinal system	0.359	0.641
Y50 Central nervous system stimulants, not elsewhere classified	0.359	0.641
Y47 Sedatives, hypnotics and antianxiety drugs	0.359	0.641
Y46 Antiepileptics and anti-Parkinsonism drugs	0.359	0.641
M93 Other osteochondropathies	0.359	0.641
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.359	0.641
Y85.0 Sequelae of motor-vehicle accident	0.358	0.642
Y41 Other systemic anti-infectives and antiparasitics	0.358	0.642
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.357	0.643
S56 Injury of muscle and tendon at forearm level	0.357	0.643
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.357	0.643
S71 Open wound of hip and thigh	0.357	0.643
M13.95 Arthritis, unspecified (Pelvic region and thigh)	0.356	0.643
M65.8 Other synovitis and tenosynovitis	0.356	0.644
M15-M19 Arthrosis	0.355	0.645
S86 Injury of muscle and tendon at lower leg level	0.355	0.645
S42.4 Fracture of lower end of humerus	0.355	0.645
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.355	0.645
S52 Fracture of forearm	0.354	0.646
S72.00 Fracture of neck of femur (closed)	0.354	0.646
Y40 Systemic antibiotics	0.354	0.646
S42.21 Fracture of upper end of humerus (open)	0.353	0.647
T91.9 Sequelae of unspecified injury of neck and trunk	0.353	0.647
S99 Other and unspecified injuries of ankle and foot	0.353	0.647
M85 Other disorders of bone density and structure	0.353	0.647
W11.6 Industrial and construction area	0.352	0.648
S62.5 Fracture of thumb	0.352	0.648
M46 Other inflammatory spondylopathies	0.351	0.649
M13.09 Polyarthritis, unspecified (Site unspecified)	0.351	0.649
Y54.5 Other diuretics	0.351	0.649
Chapter VI Diseases of the nervous system	0.351	0.649
S42.00 Fracture of clavicle (closed)	0.350	0.650
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.350	0.650
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.350	0.650
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.350	0.650
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.350	0.650
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.350	0.650
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.350	0.650
S62.4 Multiple fractures of metacarpal bones	0.349	0.651
M80 Osteoporosis with pathological fracture	0.349	0.651
S42.70 Multiple fractures of clavicle, scapula and humerus (closed)	0.349	0.651
M79.8 Other specified soft tissue disorders	0.348	0.652
S81 Open wound of lower leg	0.347	0.653
S83.6 Sprain and strain of other and unspecified parts of knee	0.347	0.653
S78 Traumatic amputation of hip and thigh	0.346	0.654
S77 Crushing injury of hip and thigh	0.346	0.654
S76 Injury of muscle and tendon at hip and thigh level	0.346	0.654
S75 Injury of blood vessels at hip and thigh level	0.346	0.654
S74 Injury of nerves at hip and thigh level	0.346	0.654
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.346	0.654
M07 Psoriatic and enteropathic arthropathies	0.346	0.654
Q80-Q89 Other congenital malformations	0.345	0.655
Y54.3 Benzothiadiazine derivatives	0.345	0.655
I24 Other acute ischaemic heart diseases	0.345	0.655
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.344	0.656
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.344	0.656
Y44 Agents primarily affecting blood constituents	0.343	0.656
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.343	0.657
W02 Fall involving ice-skates, skis, roller-skates or skateboards	0.342	0.658
W13 Fall from, out of or through building or structure	0.342	0.658
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.341	0.658
S62.6 Fracture of other finger	0.341	0.659
S88 Traumatic amputation of lower leg	0.341	0.659
S87 Crushing injury of lower leg	0.341	0.659
S85 Injury of blood vessels at lower leg level	0.341	0.659
S84 Injury of nerves at lower leg level	0.341	0.659
S12 Fracture of neck	0.340	0.660
M65.4 Radial styloid tenosynovitis [de Quervain]	0.340	0.660
M65.2 Calcific tendinitis	0.340	0.660
M65.0 Abscess of tendon sheath	0.340	0.660
Y86 Sequelae of other accidents	0.340	0.660
T93.8 Sequelae of other specified injuries of lower limb	0.340	0.660
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.340	0.660
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.340	0.660
T93.4 Sequelae of injury of nerve of lower limb	0.340	0.660
T93.0 Sequelae of open wound of lower limb	0.340	0.660
S70 Superficial injury of hip and thigh	0.340	0.660
T23 Burn and corrosion of wrist and hand	0.339	0.661
W29.9 Unspecified place	0.339	0.661
T19 Foreign body in genito-urinary tract	0.339	0.661
T15 Foreign body on external eye	0.339	0.661
V10-V19 Pedal cyclist injured in transport accident	0.338	0.662
S59 Other and unspecified injuries of forearm	0.337	0.662
S58 Traumatic amputation of forearm	0.337	0.662
S57 Crushing injury of forearm	0.337	0.662
S55 Injury of blood vessels at forearm level	0.337	0.662
S54 Injury of nerves at forearm level	0.337	0.662
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.337	0.662
S42.30 Fracture of shaft of humerus (closed)	0.337	0.663
S69 Other and unspecified injuries of wrist and hand	0.337	0.663
W18.9 Unspecified place	0.337	0.663
W18.8 Other specified place	0.337	0.663
W18.4 Street and highway	0.337	0.663
W18.2 School, other institution and public administrative area	0.337	0.663
W18.0 Home	0.337	0.663
W18.7 Farm	0.337	0.663
W18.6 Industrial and construction area	0.337	0.663
W18.1 Residential institution	0.337	0.663
G70-G73 Diseases of myoneural junction and muscle	0.337	0.663
Q21.1 Atrial septal defect	0.336	0.664
S62.8 Fracture of other and unspecified parts of wrist and hand	0.336	0.664
Q24 Other congenital malformations of heart	0.335	0.665
M45 Ankylosing spondylitis	0.335	0.665
M84 Disorders of continuity of bone	0.335	0.665
X60-X84 Intentional self-harm	0.335	0.665
M10.93 Gout, unspecified (Forearm)	0.335	0.665
M62.80 Other specified disorders of muscle (Multiple sites)	0.334	0.666
W20 Struck by thrown, projected or falling object	0.333	0.667
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.333	0.667
Q35-Q37 Cleft lip and cleft palate	0.333	0.667
Q30-Q34 Congenital malformations of the respiratory system	0.333	0.667
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.333	0.667
S20 Superficial injury of thorax	0.333	0.667
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.332	0.667
M19 Other arthrosis	0.331	0.669
W19.3 Sports and athletics area	0.331	0.669
S51 Open wound of forearm	0.330	0.670
M67.2 Synovial hypertrophy, not elsewhere classified	0.329	0.671
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.329	0.671
T58 Toxic effect of carbon monoxide	0.329	0.671
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.328	0.671
S41.8 Open wound of other and unspecified parts of shoulder girdle	0.328	0.671
S41.7 Multiple open wounds of shoulder and upper arm	0.328	0.671
S72.4 Fracture of lower end of femur	0.328	0.672
S19 Other and unspecified injuries of neck	0.328	0.672
T63 Toxic effect of contact with venomous animals	0.328	0.672
W44 Foreign body entering into or through eye or natural orifice	0.327	0.672
I98 Other disorders of circulatory system in diseases classified elsewhere	0.327	0.673
T18 Foreign body in alimentary tract	0.327	0.673
T14 Injury of unspecified body region	0.327	0.673
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.327	0.673
S32.7 Multiple fractures of lumbar spine and pelvis	0.326	0.674
M10.99 Gout, unspecified (Site unspecified)	0.326	0.674
T11 Other injuries of upper limb, level unspecified	0.324	0.675
T09 Other injuries of spine and trunk, level unspecified	0.324	0.675
T12.X1 Fracture of lower limb, level unspecified (open)	0.324	0.675
T12.X0 Fracture of lower limb, level unspecified (closed)	0.324	0.675
T12 Fracture of lower limb, level unspecified	0.324	0.675
T10.X1 Fracture of upper limb, level unspecified (open)	0.324	0.675
T10.X0 Fracture of upper limb, level unspecified (closed)	0.324	0.675
T10 Fracture of upper limb, level unspecified	0.324	0.675
T08.X1 Fracture of spine, level unspecified (open)	0.324	0.675
T08.X0 Fracture of spine, level unspecified (closed)	0.324	0.675
T08 Fracture of spine, level unspecified	0.324	0.675
M63 Disorders of muscle in diseases classified elsewhere	0.324	0.676
M61 Calcification and ossification of muscle	0.324	0.676
M60 Myositis	0.324	0.676
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.324	0.676
S72.2 Subtrochanteric fracture	0.324	0.676
S62.7 Multiple fractures of fingers	0.324	0.676
S62.1 Fracture of other carpal bone(s)	0.324	0.676
Y89 Sequelae of other external causes	0.322	0.678
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent	0.322	0.678
S30.1 Contusion of abdominal wall	0.322	0.678
Y49.2 Other and unspecified antidepressants	0.322	0.678
Q74 Other congenital malformations of limb(s)	0.322	0.678
Q63 Other congenital malformations of kidney	0.321	0.678
M10.4 Other secondary gout	0.321	0.679
M10.3 Gout due to impairment of renal function	0.321	0.679
M10.2 Drug-induced gout	0.321	0.679
M10.1 Lead-induced gout	0.321	0.679
M10.0 Idiopathic gout	0.321	0.679
Y43.3 Other antineoplastic drugs	0.321	0.679
W19.8 Other specified place	0.321	0.679
W19.5 Trade and service area	0.321	0.679
W19.0 Home	0.321	0.679
W19.7 Farm	0.321	0.679
W19.6 Industrial and construction area	0.321	0.679
W19.1 Residential institution	0.321	0.679
M79.7 Fibromyalgia	0.320	0.679
S83.7 Injury to multiple structures of knee	0.320	0.680
S83.3 Tear of articular cartilage of knee, current	0.320	0.680
S83.1 Dislocation of knee	0.320	0.680
S83.0 Dislocation of patella	0.320	0.680
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.320	0.680
M65.39 Trigger finger-Site unspec	0.319	0.681
M65.38 Trigger finger-Other	0.319	0.681
M65.37 Trigger finger-Ankle/foot	0.319	0.681
M65.36 Trigger finger-Lower leg	0.319	0.681
M65.35 Trigger finger-Pelvic/thigh	0.319	0.681
M65.33 Trigger finger-Forearm	0.319	0.681
M65.32 Trigger finger-Upper arm	0.319	0.681
M65.31 Trigger finger-Shldr region	0.319	0.681
M65.30 Trigger finger-Mult sites	0.319	0.681
Y48.4 Anaesthetic, unspecified	0.319	0.681
T93.9 Sequelae of unspecified injury of lower limb	0.319	0.681
M13.08 Polyarthritis, unspecified (Other)	0.318	0.681
M13.07 Polyarthritis, unspecified (Ankle and foot)	0.318	0.681
M13.06 Polyarthritis, unspecified (Lower leg)	0.318	0.681
M13.05 Polyarthritis, unspecified (Pelvic region and thigh)	0.318	0.681
M13.04 Polyarthritis, unspecified (Hand)	0.318	0.681
M13.03 Polyarthritis, unspecified (Forearm)	0.318	0.681
M13.02 Polyarthritis, unspecified (Upper arm)	0.318	0.681
M13.01 Polyarthritis, unspecified (Shoulder region)	0.318	0.681
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.318	0.682
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.318	0.682
S17 Crushing injury of neck	0.318	0.682
S15 Injury of blood vessels at neck level	0.318	0.682
S14 Injury of nerves and spinal cord at neck level	0.318	0.682
S11 Open wound of neck	0.318	0.682
S18 Traumatic amputation at neck level	0.318	0.682
S16 Injury of muscle and tendon at neck level	0.318	0.682
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.318	0.682
Chapter IV Endocrine, nutritional and metabolic diseases	0.317	0.683
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis	0.316	0.683
S30.2 Contusion of external genital organs	0.316	0.683
Q60 Renal agenesis and other reduction defects of kidney	0.316	0.684
T90.2 Sequelae of fracture of skull and facial bones	0.315	0.685
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.315	0.685
M46.9 Inflammatory spondylopathy, unspecified	0.315	0.685
S80 Superficial injury of lower leg	0.314	0.686
S40.0 Contusion of shoulder and upper arm	0.314	0.686
S79 Other and unspecified injuries of hip and thigh	0.314	0.686
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.313	0.686
T65 Toxic effect of other and unspecified substances	0.313	0.687
T62 Toxic effect of other noxious substances eaten as food	0.313	0.687
T61 Toxic effect of noxious substances eaten as seafood	0.313	0.687
T60 Toxic effect of pesticides	0.313	0.687
T59 Toxic effect of other gases, fumes and vapours	0.313	0.687
T57 Toxic effect of other inorganic substances	0.313	0.687
T56 Toxic effect of metals	0.313	0.687
T54 Toxic effect of corrosive substances	0.313	0.687
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.313	0.687
T52 Toxic effect of organic solvents	0.313	0.687
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.313	0.687
T55 Toxic effect of soaps and detergents	0.313	0.687
W49 Exposure to other and unspecified inanimate mechanical forces	0.313	0.687
W46 Contact with hypodermic needle	0.313	0.687
W45 Foreign body or object entering through skin	0.313	0.687
W43 Exposure to vibration	0.313	0.687
W42 Exposure to noise	0.313	0.687
W41 Exposure to high-pressure jet	0.313	0.687
W40 Explosion of other materials	0.313	0.687
W39 Discharge of firework	0.313	0.687
W38 Explosion and rupture of other specified pressurised devices	0.313	0.687
W37 Explosion and rupture of pressurised tyre, pipe or hose	0.313	0.687
W36 Explosion and rupture of gas cylinder	0.313	0.687
W35 Explosion and rupture of boiler	0.313	0.687
W34 Discharge from other and unspecified firearms	0.313	0.687
W33 Rifle, shotgun and larger firearm discharge	0.313	0.687
W32 Handgun discharge	0.313	0.687
W31 Contact with other and unspecified machinery	0.313	0.687
W30 Contact with agricultural machinery	0.313	0.687
W28 Contact with powered lawn mower	0.313	0.687
W27 Contact with nonpowered hand tool	0.313	0.687
W26 Contact with knife, sword or dagger	0.313	0.687
W24 Contact with lifting and transmission devices, not elsewhere classified	0.313	0.687
W23 Caught, crushed, jammed or pinched in or between objects	0.313	0.687
W21 Striking against or struck by sports equipment	0.313	0.687
T25 Burn and corrosion of ankle and foot	0.313	0.687
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.313	0.687
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.313	0.687
T21 Burn and corrosion of trunk	0.313	0.687
T20 Burn and corrosion of head and neck	0.313	0.687
Y52.4 Angiotensin-converting-enzyme inhibitors	0.313	0.687
W07 Fall involving chair	0.312	0.687
V23 Motorcycle rider injured in collision with car, pick-up truck or van	0.312	0.688
X59 Exposure to unspecified factor	0.312	0.688
S62.30 Fracture of other metacarpal bone (closed)	0.312	0.688
S62.0 Fracture of navicular [scaphoid] bone of hand	0.312	0.688
S90 Superficial injury of ankle and foot	0.312	0.688
S10 Superficial injury of neck	0.312	0.688
M10.97 Gout, unspecified (Ankle and foot)	0.312	0.688
S50.9 Superficial injury of forearm, unspecified	0.312	0.688
M93.9 Osteochondropathy, unspecified	0.311	0.689
Q38-Q45 Other congenital malformations of the digestive system	0.311	0.689
X23 Contact with hornets, wasps and bees	0.311	0.689
W17.4 Street and highway	0.311	0.689
S22 Fracture of rib(s), sternum and thoracic spine	0.311	0.689
S52.0 Fracture of upper end of ulna	0.311	0.689
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.310	0.690
T40.2 Other opioids	0.310	0.690
T51 Toxic effect of alcohol	0.310	0.690
S40.8 Other superficial injuries of shoulder and upper arm	0.310	0.690
S40.7 Multiple superficial injuries of shoulder and upper arm	0.310	0.690
T92.2 Sequelae of fracture at wrist and hand level	0.309	0.691
Y42.7 Androgens and anabolic congeners	0.309	0.691
T91.1 Sequelae of fracture of spine	0.308	0.692
S72.9 Fracture of femur, part unspecified	0.308	0.692
S72.8 Fractures of other parts of femur	0.308	0.692
S72.7 Multiple fractures of femur	0.308	0.692
T17.2 Foreign body in pharynx	0.307	0.693
G70 Myasthenia gravis and other myoneural disorders	0.307	0.693
W06.2 School, other institution and public administrative area	0.307	0.693
W06.9 Unspecified place	0.307	0.693
W06.8 Other specified place	0.307	0.693

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations