TreeWAS – Variant ID: rs12129731

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I85.9 Oesophageal varices without bleeding	0.000	0.911	0.089
I85 Oesophageal varices	0.000	0.924	0.076
I85.0 Oesophageal varices with bleeding	0.000	0.925	0.075
G93.9 Disorder of brain, unspecified	0.000	0.958	0.042
G93 Other disorders of brain	0.000	0.959	0.041
G93.0 Cerebral cysts	0.000	0.960	0.040
G93.2 Benign intracranial hypertension	0.000	0.961	0.039
G93.8 Other specified disorders of brain	0.000	0.964	0.036
G93.5 Compression of brain	0.000	0.968	0.032
G93.6 Cerebral oedema	0.000	0.968	0.032
G93.4 Encephalopathy, unspecified	0.000	0.969	0.031
G93.7 Reye's syndrome	0.000	0.970	0.030
G93.3 Postviral fatigue syndrome	0.000	0.971	0.029
M10.99 Gout, unspecified (Site unspecified)	0.000	0.972	0.028
H53.0 Amblyopia ex anopsia	0.000	0.975	0.025
Z99.1 Dependence on respirator	0.000	0.977	0.023
H53.9 Visual disturbance, unspecified	0.000	0.980	0.020
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.000	0.981	0.019
G93.1 Anoxic brain damage, not elsewhere classified	0.000	0.982	0.018
Z99.2 Dependence on renal dialysis	0.000	0.982	0.018
Z99.3 Dependence on wheelchair	0.000	0.982	0.018
H53 Visual disturbances	0.000	0.983	0.017
K76.8 Other specified diseases of liver	0.000	0.985	0.015
K80.4 Calculus of bile duct with cholecystitis	0.015	0.985	0.000
M10.9 Gout, unspecified	0.000	0.985	0.015
K70.9 Alcoholic liver disease, unspecified	0.000	0.986	0.014
Z99.4 Dependence on artificial heart	0.000	0.986	0.014
Z99.0 Dependence on aspirator	0.000	0.986	0.014
M10.97 Gout, unspecified (Ankle and foot)	0.000	0.986	0.014
H53.4 Visual field defects	0.000	0.986	0.014
Z99.9 Dependence on unspecified enabling machine and device	0.000	0.987	0.012
H53.6 Night blindness	0.000	0.988	0.012
H53.5 Colour vision deficiencies	0.000	0.988	0.012
H53.3 Other disorders of binocular vision	0.000	0.988	0.012
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.000	0.988	0.012
M10.90 Gout, unspecified (Multiple sites)	0.000	0.988	0.012
N03.9 Unspecified	0.000	0.988	0.012
Z99.8 Dependence on other enabling machines and devices	0.000	0.988	0.012
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.000	0.989	0.011
M10.98 Gout, unspecified (Other)	0.000	0.989	0.011
M10.95 Gout, unspecified (Pelvic region and thigh)	0.000	0.989	0.011
M10.91 Gout, unspecified (Shoulder region)	0.000	0.989	0.011
M10.93 Gout, unspecified (Forearm)	0.000	0.989	0.011
I98.2 Oesophageal varices in diseases classified elsewhere	0.000	0.989	0.011
K70 Alcoholic liver disease	0.000	0.989	0.011
K76 Other diseases of liver	0.000	0.990	0.010
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.000	0.990	0.010
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.000	0.990	0.010
T82.0 Mechanical complication of heart valve prosthesis	0.000	0.990	0.010
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.000	0.990	0.010
T82.3 Mechanical complication of other vascular grafts	0.000	0.990	0.010
Z43.2 Attention to ileostomy	0.000	0.991	0.009
M10.94 Gout, unspecified (Hand)	0.000	0.991	0.009
M10.92 Gout, unspecified (Upper arm)	0.000	0.991	0.009
H53.1 Subjective visual disturbances	0.000	0.991	0.009
K76.7 Hepatorenal syndrome	0.000	0.991	0.009
K70.4 Alcoholic hepatic failure	0.000	0.991	0.009
K70.2 Alcoholic fibrosis and sclerosis of liver	0.000	0.991	0.009
K70-K77 Diseases of liver	0.000	0.991	0.009
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.000	0.992	0.008
K76.6 Portal hypertension	0.000	0.992	0.008
K70.0 Alcoholic fatty liver	0.000	0.992	0.008
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.000	0.992	0.008
K72.9 Hepatic failure, unspecified	0.000	0.992	0.008
M10.96 Gout, unspecified (Lower leg)	0.000	0.992	0.008
T82.4 Mechanical complication of vascular dialysis catheter	0.000	0.992	0.008
K76.5 Hepatic veno-occlusive disease	0.000	0.992	0.007
K76.4 Peliosis hepatis	0.000	0.992	0.007
K76.3 Infarction of liver	0.000	0.992	0.007
K76.2 Central haemorrhagic necrosis of liver	0.000	0.992	0.007
K76.1 Chronic passive congestion of liver	0.000	0.993	0.007
K14.0 Glossitis	0.000	0.993	0.007
K72 Hepatic failure, not elsewhere classified	0.000	0.993	0.007
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.000	0.993	0.007
K73 Chronic hepatitis, not elsewhere classified	0.000	0.993	0.007
K20 Oesophagitis	0.000	0.993	0.007
I98 Other disorders of circulatory system in diseases classified elsewhere	0.000	0.993	0.007
K77 Liver disorders in diseases classified elsewhere	0.000	0.994	0.006
K71 Toxic liver disease	0.000	0.994	0.006
K70.3 Alcoholic cirrhosis of liver	0.000	0.994	0.006
D52.9 Folate deficiency anaemia, unspecified	0.000	0.994	0.006
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.006	0.994	0.000
A41.0 Septicaemia due to Staphylococcus aureus	0.000	0.994	0.006
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.000	0.994	0.006
M66.06 Rupture of popliteal cyst-Lower leg	0.006	0.994	0.000
H53.8 Other visual disturbances	0.000	0.995	0.005
L43.9 Lichen planus, unspecified	0.000	0.995	0.005
K14.8 Other diseases of tongue	0.000	0.995	0.005
T82.1 Mechanical complication of cardiac electronic device	0.000	0.995	0.005
K73.9 Chronic hepatitis, unspecified	0.000	0.995	0.005
K73.8 Other chronic hepatitis, not elsewhere classified	0.000	0.995	0.005
K73.2 Chronic active hepatitis, not elsewhere classified	0.000	0.995	0.005
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.000	0.995	0.005
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.000	0.995	0.005
K75 Other inflammatory liver diseases	0.000	0.995	0.005
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.000	0.995	0.005
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.995	0.005
I98.0 Cardiovascular syphilis	0.000	0.995	0.005
A41.5 Septicaemia due to other Gram-negative organisms	0.000	0.995	0.005
G04 Encephalitis, myelitis and encephalomyelitis	0.000	0.995	0.005
K77.8 Liver disorders in other diseases classified elsewhere	0.000	0.995	0.005
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.000	0.995	0.005
K70.1 Alcoholic hepatitis	0.000	0.995	0.005
N03 Chronic nephritic syndrome	0.000	0.995	0.005
K72.1 Chronic hepatic failure	0.000	0.995	0.005
K75.8 Other specified inflammatory liver diseases	0.000	0.995	0.005
K14 Diseases of tongue	0.000	0.995	0.005
K71.9 Toxic liver disease, unspecified	0.000	0.995	0.004
K71.8 Toxic liver disease with other disorders of liver	0.000	0.995	0.004
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.000	0.995	0.004
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.000	0.995	0.004
K71.5 Toxic liver disease with chronic active hepatitis	0.000	0.995	0.004
K71.4 Toxic liver disease with chronic lobular hepatitis	0.000	0.995	0.004
K71.3 Toxic liver disease with chronic persistent hepatitis	0.000	0.995	0.004
K71.2 Toxic liver disease with acute hepatitis	0.000	0.995	0.004
A41 Other septicaemia	0.000	0.995	0.005
K71.0 Toxic liver disease with cholestasis	0.000	0.995	0.004
K71.1 Toxic liver disease with hepatic necrosis	0.000	0.995	0.004
S19.9 Unspecified injury of neck	0.000	0.995	0.005
A41.2 Septicaemia due to unspecified staphylococcus	0.000	0.996	0.004
R49.0 Dysphonia	0.004	0.996	0.000
K60.1 Chronic anal fissure	0.000	0.996	0.004
K74 Fibrosis and cirrhosis of liver	0.000	0.996	0.004
K75.4 Autoimmune hepatitis	0.000	0.996	0.004
O21.0 Mild hyperemesis gravidarum	0.004	0.996	0.000
M66.0 Rupture of popliteal cyst	0.004	0.996	0.000
K74.6 Other and unspecified cirrhosis of liver	0.000	0.996	0.004
M10 Gout	0.000	0.996	0.004
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.004	0.996	0.000
K75.2 Nonspecific reactive hepatitis	0.000	0.996	0.004
K75.1 Phlebitis of portal vein	0.000	0.996	0.004
G04.8 Other encephalitis, myelitis and encephalomyelitis	0.000	0.996	0.004
M76.67 Achilles tendinitis (Ankle and foot)	0.004	0.996	0.000
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.004	0.996	0.000
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified	0.000	0.996	0.004
G04.1 Tropical spastic paraplegia	0.000	0.996	0.004
K75.3 Granulomatous hepatitis, not elsewhere classified	0.000	0.996	0.004
N03.8 Other	0.000	0.996	0.004
N03.7 Diffuse crescentic glomerulonephritis	0.000	0.996	0.004
N03.6 Dense deposit disease	0.000	0.996	0.004
N03.4 Diffuse endocapillary proliferative glomerulonephritis	0.000	0.996	0.004
N03.3 Diffuse mesangial proliferative glomerulonephritis	0.000	0.996	0.004
N03.2 Diffuse membranous glomerulonephritis	0.000	0.996	0.004
N03.1 Focal and segmental glomerular lesions	0.000	0.996	0.004
N03.0 Minor glomerular abnormality	0.000	0.996	0.004
O82.0 Delivery by elective Caesarean section	0.000	0.996	0.004
K14.5 Plicated tongue	0.000	0.996	0.004
K14.4 Atrophy of tongue papillae	0.000	0.996	0.004
K14.2 Median rhomboid glossitis	0.000	0.996	0.004
I72.4 Aneurysm of artery of lower extremity	0.000	0.996	0.004
K14.6 Glossodynia	0.000	0.996	0.004
A41.4 Septicaemia due to anaerobes	0.000	0.996	0.003
A41.3 Septicaemia due to Haemophilus influenzae	0.000	0.996	0.003
H80.9 Otosclerosis, unspecified	0.000	0.996	0.004
T93.9 Sequelae of unspecified injury of lower limb	0.004	0.996	0.000
M95.0 Acquired deformity of nose	0.000	0.996	0.004
O21 Excessive vomiting in pregnancy	0.004	0.996	0.000
N03.5 Diffuse mesangiocapillary glomerulonephritis	0.000	0.997	0.003
G04.0 Acute disseminated encephalitis	0.000	0.997	0.003
K14.3 Hypertrophy of tongue papillae	0.000	0.997	0.003
K72.0 Acute and subacute hepatic failure	0.000	0.997	0.003
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.003	0.997	0.000
C34.9 Bronchus or lung, unspecified	0.000	0.997	0.003
J46 Status asthmaticus	0.003	0.997	0.000
K74.4 Secondary biliary cirrhosis	0.000	0.997	0.003
K74.2 Hepatic fibrosis with hepatic sclerosis	0.000	0.997	0.003
K74.1 Hepatic sclerosis	0.000	0.997	0.003
O82.1 Delivery by emergency Caesarean section	0.000	0.997	0.003
A41.1 Septicaemia due to other specified staphylococcus	0.000	0.997	0.003
M66.09 Rupture of popliteal cyst-Site unspec	0.003	0.997	0.000
M66.08 Rupture of popliteal cyst-Other	0.003	0.997	0.000
M66.07 Rupture of popliteal cyst-Ankle/foot	0.003	0.997	0.000
M66.05 Rupture of popliteal cyst-Pelvic/thigh	0.003	0.997	0.000
M66.04 Rupture of popliteal cyst-Hand	0.003	0.997	0.000
M66.03 Rupture of popliteal cyst-Forearm	0.003	0.997	0.000
M66.02 Rupture of popliteal cyst-Upper arm	0.003	0.997	0.000
M66.01 Rupture of popliteal cyst-Shldr region	0.003	0.997	0.000
M66.00 Rupture of popliteal cyst-Mult sites	0.003	0.997	0.000
K14.9 Disease of tongue, unspecified	0.000	0.997	0.003
A41.9 Septicaemia, unspecified	0.000	0.997	0.003
K14.1 Geographic tongue	0.000	0.997	0.003
F00.9 Dementia in Alzheimer's disease, unspecified	0.003	0.997	0.000
M66 Spontaneous rupture of synovium and tendon	0.003	0.997	0.000
M10.4 Other secondary gout	0.000	0.997	0.003
M10.3 Gout due to impairment of renal function	0.000	0.997	0.003
M10.2 Drug-induced gout	0.000	0.997	0.003
M10.1 Lead-induced gout	0.000	0.997	0.003
H53-H54 Visual disturbances and blindness	0.000	0.997	0.003
M66.2 Spontaneous rupture of extensor tendons	0.003	0.997	0.000
O21.9 Vomiting of pregnancy, unspecified	0.003	0.997	0.000
O82 Single delivery by Caesarean section	0.000	0.997	0.003
D52 Folate deficiency anaemia	0.000	0.997	0.003
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.000	0.997	0.003
T93.8 Sequelae of other specified injuries of lower limb	0.003	0.997	0.000
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.000	0.997	0.003
M76.6 Achilles tendinitis	0.003	0.997	0.000
O21.8 Other vomiting complicating pregnancy	0.003	0.997	0.000
M66.24 Spontaneous rupture of extensor tendons (Hand)	0.003	0.997	0.000
M66.4 Spontaneous rupture of other tendons	0.003	0.997	0.000
M66.27 Spontaneous rupture of extensor tendons (Ankle and foot)	0.003	0.997	0.000
M76.66 Achilles tendinitis (Lower leg)	0.003	0.997	0.000
I95.2 Hypotension due to drugs	0.000	0.997	0.003
K74.5 Biliary cirrhosis, unspecified	0.000	0.997	0.003
Q50.4 Embryonic cyst of Fallopian tube	0.003	0.997	0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.000	0.997	0.003
T93 Sequelae of injuries of lower limb	0.003	0.997	0.000
T93.0 Sequelae of open wound of lower limb	0.003	0.997	0.000
H53.2 Diplopia	0.000	0.997	0.003
O21.2 Late vomiting of pregnancy	0.002	0.997	0.000
W29.9 Unspecified place	0.003	0.997	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.000	0.997	0.003
M66.3 Spontaneous rupture of flexor tendons	0.002	0.997	0.000
O82.9 Delivery by Caesarean section, unspecified	0.000	0.997	0.003
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O32.0 Maternal care for unstable lie	0.003	0.997	0.000
R47.0 Dysphasia and aphasia	0.000	0.997	0.003
M66.5 Spontaneous rupture of unspecified tendon	0.002	0.997	0.000
M66.1 Rupture of synovium	0.002	0.997	0.000
M82.1 Osteoporosis in endocrine disorders	0.000	0.997	0.003
M10.19 Lead-induced gout (Site unspecified)	0.000	0.997	0.002
M10.18 Lead-induced gout (Other)	0.000	0.997	0.002
M10.17 Lead-induced gout (Ankle and foot)	0.000	0.997	0.002
M10.16 Lead-induced gout (Lower leg)	0.000	0.997	0.002
M10.15 Lead-induced gout (Pelvic region and thigh)	0.000	0.997	0.002
M10.14 Lead-induced gout (Hand)	0.000	0.997	0.002
M10.13 Lead-induced gout (Forearm)	0.000	0.997	0.002
M10.12 Lead-induced gout (Upper arm)	0.000	0.997	0.002
M10.11 Lead-induced gout (Shoulder region)	0.000	0.997	0.002
M10.10 Lead-induced gout (Multiple sites)	0.000	0.997	0.002
M10.29 Drug-induced gout (Site unspecified)	0.000	0.997	0.002
M10.28 Drug-induced gout (Other)	0.000	0.997	0.002
M10.27 Drug-induced gout (Ankle and foot)	0.000	0.997	0.002
M10.26 Drug-induced gout (Lower leg)	0.000	0.997	0.002
M10.25 Drug-induced gout (Pelvic region and thigh)	0.000	0.997	0.002
M10.24 Drug-induced gout (Hand)	0.000	0.997	0.002
M10.23 Drug-induced gout (Forearm)	0.000	0.997	0.002
M10.22 Drug-induced gout (Upper arm)	0.000	0.997	0.002
M10.21 Drug-induced gout (Shoulder region)	0.000	0.997	0.002
M10.20 Drug-induced gout (Multiple sites)	0.000	0.997	0.002
M10.39 Gout due to impairment of renal function (Site unspecified)	0.000	0.997	0.002
M10.38 Gout due to impairment of renal function (Other)	0.000	0.997	0.002
M10.37 Gout due to impairment of renal function (Ankle and foot)	0.000	0.997	0.002
M10.36 Gout due to impairment of renal function (Lower leg)	0.000	0.997	0.002
M10.35 Gout due to impairment of renal function (Pelvic region and thigh)	0.000	0.997	0.002
M10.34 Gout due to impairment of renal function (Hand)	0.000	0.997	0.002
M10.33 Gout due to impairment of renal function (Forearm)	0.000	0.997	0.002
M10.32 Gout due to impairment of renal function (Upper arm)	0.000	0.997	0.002
M10.31 Gout due to impairment of renal function (Shoulder region)	0.000	0.997	0.002
M10.30 Gout due to impairment of renal function (Multiple sites)	0.000	0.997	0.002
M10.49 Other secondary gout (Site unspecified)	0.000	0.997	0.002
M10.48 Other secondary gout (Other)	0.000	0.997	0.002
M10.47 Other secondary gout (Ankle and foot)	0.000	0.997	0.002
M10.46 Other secondary gout (Lower leg)	0.000	0.997	0.002
M10.45 Other secondary gout (Pelvic region and thigh)	0.000	0.997	0.002
M10.44 Other secondary gout (Hand)	0.000	0.997	0.002
M10.43 Other secondary gout (Forearm)	0.000	0.997	0.002
M10.42 Other secondary gout (Upper arm)	0.000	0.997	0.002
M10.41 Other secondary gout (Shoulder region)	0.000	0.997	0.002
M10.40 Other secondary gout (Multiple sites)	0.000	0.997	0.002
I95.8 Other hypotension	0.000	0.997	0.003
K76.0 Fatty (change of) liver, not elsewhere classified	0.000	0.997	0.003
R00.8 Other and unspecified abnormalities of heart beat	0.003	0.997	0.000
I95.0 Idiopathic hypotension	0.000	0.997	0.002
S19 Other and unspecified injuries of neck	0.000	0.997	0.002
M66.29 Spontaneous rupture of extensor tendons (Site unspecified)	0.002	0.998	0.000
M66.28 Spontaneous rupture of extensor tendons-Other	0.002	0.998	0.000
M66.26 Spontaneous rupture of extensor tendons (Lower leg)	0.002	0.998	0.000
M66.25 Spontaneous rupture of extensor tendons (Pelvic region and thigh)	0.002	0.998	0.000
M66.23 Spontaneous rupture of extensor tendons (Forearm)	0.002	0.998	0.000
M66.22 Spontaneous rupture of extensor tendons (Upper arm)	0.002	0.998	0.000
M66.21 Spontaneous rupture of extensor tendons (Shoulder region)	0.002	0.998	0.000
M66.20 Spontaneous rupture of extensor tendons (Multiple sites)	0.002	0.998	0.000
M66.41 Spontaneous rupture of other tendons (Shoulder region)	0.002	0.998	0.000
O82.8 Other single delivery by Caesarean section	0.000	0.998	0.002
O82.2 Delivery by Caesarean hysterectomy	0.000	0.998	0.002
T93.1 Sequelae of fracture of femur	0.002	0.998	0.000
D52.8 Other folate deficiency anaemias	0.000	0.998	0.002
D52.1 Drug-induced folate deficiency anaemia	0.000	0.998	0.002
D52.0 Dietary folate deficiency anaemia	0.000	0.998	0.002
G01 Meningitis in bacterial diseases classified elsewhere	0.000	0.998	0.002
L43 Lichen planus	0.000	0.998	0.002
Q61.3 Polycystic kidney, unspecified	0.000	0.998	0.002
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.000	0.998	0.002
K76.9 Liver disease, unspecified	0.000	0.998	0.002
R23.3 Spontaneous ecchymoses	0.000	0.998	0.002
K75.9 Inflammatory liver disease, unspecified	0.000	0.998	0.002
M76.69 Achilles tendinitis-Site unspec	0.002	0.998	0.000
M76.68 Achilles tendinitis-Other	0.002	0.998	0.000
M76.65 Achilles tendinitis-Pelvic/Thigh	0.002	0.998	0.000
M76.64 Achilles tendinitis-Hand	0.002	0.998	0.000
M76.63 Achilles tendinitis-Forearm	0.002	0.998	0.000
M76.62 Achilles tendinitis-Upper arm	0.002	0.998	0.000
M76.61 Achilles tendinitis-Shldr region	0.002	0.998	0.000
M76.60 Achilles tendinitis (Multiple sites)	0.002	0.998	0.000
R60.0 Localised oedema	0.000	0.998	0.002
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.002	0.998	0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
O32.2 Maternal care for transverse and oblique lie	0.002	0.998	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.002	0.998	0.000
K74.0 Hepatic fibrosis	0.000	0.998	0.002
M10.0 Idiopathic gout	0.001	0.998	0.001
M66.36 Spontaneous rupture of flexor tendons (Lower leg)	0.002	0.998	0.000
M66.49 Spontaneous rupture of other tendons (Site unspecified)	0.002	0.998	0.000
M66.48 Spontaneous rupture of other tendons (Other)	0.002	0.998	0.000
M66.47 Spontaneous rupture of other tendons (Ankle and foot)	0.002	0.998	0.000
M66.45 Spontaneous rupture of other tendons (Pelvic region and thigh)	0.002	0.998	0.000
M66.44 Spontaneous rupture of other tendons (Hand)	0.002	0.998	0.000
M66.43 Spontaneous rupture of other tendons (Forearm)	0.002	0.998	0.000
M66.42 Spontaneous rupture of other tendons (Upper arm)	0.002	0.998	0.000
M66.40 Spontaneous rupture of other tendons (Multiple sites)	0.002	0.998	0.000
I95 Hypotension	0.000	0.998	0.002
Q61 Cystic kidney disease	0.000	0.998	0.002
M66.46 Spontaneous rupture of other tendons (Lower leg)	0.002	0.998	0.000
Q61.0 Congenital single renal cyst	0.000	0.998	0.002
I95-I99 Other and unspecified disorders of the circulatory system	0.000	0.998	0.002
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.002	0.998	0.000
T93.4 Sequelae of injury of nerve of lower limb	0.002	0.998	0.000
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance	0.002	0.998	0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.002	0.998	0.000
R40.0 Somnolence	0.000	0.998	0.002
H20.8 Other iridocyclitis	0.000	0.998	0.002
S63.7 Sprain and strain of other and unspecified parts of hand	0.002	0.998	0.000
A46 Erysipelas	0.000	0.998	0.002
M66.39 Spontaneous rupture of flexor tendons (Site unspecified)	0.002	0.998	0.000
M66.38 Spontaneous rupture of flexor tendons (Other)	0.002	0.998	0.000
M66.37 Spontaneous rupture of flexor tendons (Ankle and foot)	0.002	0.998	0.000
M66.35 Spontaneous rupture of flexor tendons (Pelvic region and thigh)	0.002	0.998	0.000
M66.33 Spontaneous rupture of flexor tendons (Forearm)	0.002	0.998	0.000
M66.32 Spontaneous rupture of flexor tendons (Upper arm)	0.002	0.998	0.000
M66.31 Spontaneous rupture of flexor tendons (Shoulder region)	0.002	0.998	0.000
M66.30 Spontaneous rupture of flexor tendons (Multiple sites)	0.002	0.998	0.000
L03.9 Cellulitis, unspecified	0.000	0.998	0.002
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
Q61.5 Medullary cystic kidney	0.000	0.998	0.002
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.000	0.998	0.002
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere	0.000	0.998	0.002
G00.1 Pneumococcal meningitis	0.000	0.998	0.002
H40.9 Glaucoma, unspecified	0.002	0.998	0.000
G06 Intracranial and intraspinal abscess and granuloma	0.000	0.998	0.002
G00 Bacterial meningitis, not elsewhere classified	0.000	0.998	0.002
M66.19 Rupture of synovium (Site unspecified)	0.002	0.998	0.000
M66.18 Rupture of synovium (Other)	0.002	0.998	0.000
M66.17 Rupture of synovium (Ankle and foot)	0.002	0.998	0.000
M66.16 Rupture of synovium (Lower leg)	0.002	0.998	0.000
M66.15 Rupture of synovium (Pelvic region and thigh)	0.002	0.998	0.000
M66.14 Rupture of synovium (Hand)	0.002	0.998	0.000
M66.13 Rupture of synovium (Forearm)	0.002	0.998	0.000
M66.12 Rupture of synovium (Upper arm)	0.002	0.998	0.000
M66.11 Rupture of synovium (Shoulder region)	0.002	0.998	0.000
M66.10 Rupture of synovium (Multiple sites)	0.002	0.998	0.000
M66.59 Spontaneous rupture of unspecified tendon (Site unspecified)	0.002	0.998	0.000
M66.58 Spontaneous rupture of unspecified tendon (Other)	0.002	0.998	0.000
M66.57 Spontaneous rupture of unspecified tendon (Ankle and foot)	0.002	0.998	0.000
M66.56 Spontaneous rupture of unspecified tendon (Lower leg)	0.002	0.998	0.000
M66.55 Spontaneous rupture of unspecified tendon (Pelvic region and thigh)	0.002	0.998	0.000
M66.54 Spontaneous rupture of unspecified tendon (Hand)	0.002	0.998	0.000
M66.53 Spontaneous rupture of unspecified tendon (Forearm)	0.002	0.998	0.000
M66.52 Spontaneous rupture of unspecified tendon (Upper arm)	0.002	0.998	0.000
M66.51 Spontaneous rupture of unspecified tendon (Shoulder region)	0.002	0.998	0.000
M66.50 Spontaneous rupture of unspecified tendon (Multiple sites)	0.002	0.998	0.000
M82.19 Osteoporosis in endocrine disorders (Site unspecified)	0.000	0.998	0.002
M82.18 Osteoporosis in endocrine disorders (Other)	0.000	0.998	0.002
M82.17 Osteoporosis in endocrine disorders (Ankle and foot)	0.000	0.998	0.002
M82.16 Osteoporosis in endocrine disorders (Lower leg)	0.000	0.998	0.002
M82.15 Osteoporosis in endocrine disorders (Pelvic region and thigh)	0.000	0.998	0.002
M82.14 Osteoporosis in endocrine disorders (Hand)	0.000	0.998	0.002
M82.13 Osteoporosis in endocrine disorders (Forearm)	0.000	0.998	0.002
M82.12 Osteoporosis in endocrine disorders (Upper arm)	0.000	0.998	0.002
S63.6 Sprain and strain of finger(s)	0.002	0.998	0.000
A41.8 Other specified septicaemia	0.000	0.998	0.002
A48.1 Legionnaires' disease	0.000	0.998	0.002
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.002	0.998	0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
Q87.4 Marfan's syndrome	0.002	0.998	0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
S19.7 Multiple injuries of neck	0.000	0.998	0.002
Z97.4 Presence of external hearing-aid	0.000	0.998	0.002
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.000	0.998	0.002
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.002	0.998	0.000
L43.3 Subacute (active) lichen planus	0.000	0.998	0.002
L43.2 Lichenoid drug reaction	0.000	0.998	0.002
L43.1 Bullous lichen planus	0.000	0.998	0.002
L43.0 Hypertrophic lichen planus	0.000	0.998	0.002
Q50.5 Embryonic cyst of broad ligament	0.002	0.998	0.000
Q87.1 Congenital malformation syndromes predominantly associated with short stature	0.002	0.998	0.000
M66.34 Spontaneous rupture of flexor tendons (Hand)	0.002	0.998	0.000
D14.1 Larynx	0.002	0.998	0.000
O32.8 Maternal care for other malpresentation of foetus	0.002	0.998	0.000
S13.6 Sprain and strain of joints and ligaments of other and unspecified parts of neck	0.000	0.998	0.002
Q61.2 Polycystic kidney, adult type	0.000	0.998	0.002
G06.0 Intracranial abscess and granuloma	0.000	0.998	0.002
I15.1 Hypertension secondary to other renal disorders	0.000	0.998	0.002
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.002	0.998	0.000
S63.2 Multiple dislocations of fingers	0.002	0.998	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
S19.8 Other specified injuries of neck	0.000	0.998	0.002
M10.08 Idiopathic gout (Other)	0.001	0.998	0.001
M10.06 Idiopathic gout (Lower leg)	0.001	0.998	0.001
M10.05 Idiopathic gout (Pelvic region and thigh)	0.001	0.998	0.001
M10.04 Idiopathic gout (Hand)	0.001	0.998	0.001
M10.03 Idiopathic gout (Forearm)	0.001	0.998	0.001
M10.01 Idiopathic gout (Shoulder region)	0.001	0.998	0.001
J92.0 Pleural plaque with presence of asbestos	0.000	0.998	0.002
K75.0 Abscess of liver	0.000	0.998	0.002
L43.8 Other lichen planus	0.000	0.998	0.002
A48 Other bacterial diseases, not elsewhere classified	0.000	0.998	0.002
G09 Sequelae of inflammatory diseases of central nervous system	0.000	0.998	0.002
O32 Maternal care for known or suspected malpresentation of foetus	0.002	0.998	0.000
Q61.9 Cystic kidney disease, unspecified	0.000	0.998	0.002
Q61.8 Other cystic kidney diseases	0.000	0.998	0.002
Q61.4 Renal dysplasia	0.000	0.998	0.002
Q61.1 Polycystic kidney, infantile type	0.000	0.998	0.002
S63.3 Traumatic rupture of ligament of wrist and carpus	0.002	0.998	0.000
J99.1 Respiratory disorders in other diffuse connective tissue disorders	0.002	0.998	0.000
M10.02 Idiopathic gout (Upper arm)	0.001	0.998	0.001
S13.1 Dislocation of cervical vertebra	0.000	0.998	0.002
A30-A49 Other bacterial diseases	0.000	0.998	0.002
M10.00 Idiopathic gout (Multiple sites)	0.001	0.998	0.001
B18.2 Chronic viral hepatitis C	0.002	0.998	0.000
O32.3 Maternal care for face, brow and chin presentation	0.002	0.998	0.000
S63.1 Dislocation finger	0.002	0.998	0.000
G90.0 Idiopathic peripheral autonomic neuropathy	0.000	0.998	0.002
Q87.2 Congenital malformation syndromes predominantly involving limbs	0.002	0.998	0.000
R27.0 Ataxia, unspecified	0.000	0.998	0.002
M10.09 Idiopathic gout (Site unspecified)	0.001	0.998	0.001
G05.8 Encephalitis, myelitis and encephalomyelitis in other diseases classified elsewhere	0.000	0.998	0.002
G05.2 Encephalitis, myelitis and encephalomyelitis in other infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
G05.0 Encephalitis, myelitis and encephalomyelitis in bacterial diseases classified elsewhere	0.000	0.998	0.002
H74.8 Other specified disorders of middle ear and mastoid	0.002	0.998	0.000
G03 Meningitis due to other and unspecified causes	0.000	0.998	0.002
G00.8 Other bacterial meningitis	0.000	0.998	0.002
G00.3 Staphylococcal meningitis	0.000	0.998	0.002
G00.0 Haemophilus meningitis	0.000	0.998	0.002
G06.2 Extradural and subdural abscess, unspecified	0.000	0.998	0.002
Y43.3 Other antineoplastic drugs	0.000	0.998	0.002
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.000	0.998	0.002
D41.4 Bladder	0.002	0.998	0.000
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere	0.000	0.998	0.002
L85.8 Other specified epidermal thickening	0.000	0.998	0.002
M10.07 Idiopathic gout (Ankle and foot)	0.001	0.998	0.001
G02.8 Meningitis in other specified infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
G02.1 Meningitis in mycoses	0.000	0.998	0.002
F00 Dementia in Alzheimer's disease	0.002	0.998	0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.000	0.998	0.002
H18.9 Disorder of cornea, unspecified	0.002	0.998	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.002	0.998	0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.000	0.998	0.002
L73.2 Hidradenitis suppurativa	0.002	0.998	0.000
Q87.5 Other congenital malformation syndromes with other skeletal changes	0.002	0.998	0.000
Q87.3 Congenital malformation syndromes involving early overgrowth	0.002	0.998	0.000
S22.10 Multiple fractures of thoracic spine (closed)	0.002	0.998	0.000
J99.0 Rheumatoid lung disease	0.002	0.998	0.000
I26 Pulmonary embolism	0.000	0.998	0.002
C18.6 Descending colon	0.000	0.998	0.002
K12.3 Oral mucositis (ulcerative)	0.000	0.998	0.002
L81.4 Other melanin hyperpigmentation	0.002	0.998	0.000
O32.4 Maternal care for high head at term	0.002	0.998	0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
H74 Other disorders of middle ear and mastoid	0.002	0.998	0.000
H80 Otosclerosis	0.000	0.998	0.002
G90-G99 Other disorders of the nervous system	0.000	0.998	0.002
G02.0 Meningitis in viral diseases classified elsewhere	0.000	0.998	0.002
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
K74.3 Primary biliary cirrhosis	0.000	0.998	0.001
Q50.6 Other congenital malformatons of Fallopian tube and broad ligament	0.002	0.998	0.000
Q50.3 Other congenital malformations of ovary	0.002	0.998	0.000
Q50.2 Congenital torsion of ovary	0.002	0.998	0.000
Q50.1 Developmental ovarian cyst	0.002	0.998	0.000
Q50.0 Congenital absence of ovary	0.002	0.998	0.000
T46.1 Calcium-channel blockers	0.000	0.998	0.002
F00.1 Dementia in Alzheimer's disease with late onset	0.002	0.998	0.000
G00.2 Streptococcal meningitis	0.000	0.998	0.001
S13.4 Sprain and strain of cervical spine	0.000	0.998	0.002
A48.4 Brazilian purpuric fever	0.000	0.998	0.001
A48.3 Toxic shock syndrome	0.000	0.998	0.001
A48.2 Nonpneumonic Legionnaires' disease [Pontiac fever]	0.000	0.998	0.001
A48.0 Gas gangrene	0.000	0.998	0.001
O32.6 Maternal care for compound presentation	0.002	0.998	0.000
G58.8 Other specified mononeuropathies	0.002	0.998	0.000
I45.5 Other specified heart block	0.002	0.998	0.000
S63.5 Sprain and strain of wrist	0.001	0.998	0.000
G94 Other disorders of brain in diseases classified elsewhere	0.000	0.998	0.002
Q87.8 Other specified congenital malformation syndromes, not elsewhere classified	0.001	0.998	0.000
G90 Disorders of autonomic nervous system	0.000	0.998	0.002
M94.88 Other specified disorders of cartilage (Other)	0.002	0.998	0.000
S63.11 Subluxation and dislocation of metacarpophalangeal joint of thumb	0.001	0.998	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.998	0.002
S63.0 Dislocation of wrist	0.001	0.998	0.000
A44 Bartonellosis	0.000	0.998	0.001
A43 Nocardiosis	0.000	0.998	0.001
A42 Actinomycosis	0.000	0.998	0.001
A37 Whooping cough	0.000	0.998	0.001
A36 Diphtheria	0.000	0.998	0.001
A32 Listeriosis	0.000	0.998	0.001
A30 Leprosy [Hansen's disease]	0.000	0.998	0.001
A38 Scarlet fever	0.000	0.998	0.001
A35 Other tetanus	0.000	0.998	0.001
A34 Obstetrical tetanus	0.000	0.998	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations