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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12190030
log Bayes Factor = 68.2872
Chromosome 6   position 30,921,364  (GRCh37) Explore rs12190030 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
L40 Psoriasis
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.001 0.999
E03 Other hypothyroidism
0.000 0.001 0.999
E03.9 Hypothyroidism, unspecified
0.000 0.001 0.999
L40.0 Psoriasis vulgaris
0.997 0.003 0.000
F33 Recurrent depressive disorder
0.995 0.005 0.000
F30-F39 Mood [affective] disorders
0.995 0.005 0.000
F33.9 Recurrent depressive disorder, unspecified
0.994 0.006 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.015 0.985
Chapter V Mental and behavioural disorders
0.984 0.016 0.000
E10-E14 Diabetes mellitus
0.000 0.017 0.983
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.017 0.983
E10.3 With ophthalmic complications
0.000 0.024 0.976
F40-F48 Neurotic, stress-related and somatoform disorders
0.970 0.030 0.000
E10.4 With neurological complications
0.000 0.033 0.967
F31 Bipolar affective disorder
0.964 0.036 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.047 0.953
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.942 0.058 0.000
E10.1 With ketoacidosis
0.000 0.063 0.937
E16 Other disorders of pancreatic internal secretion
0.000 0.069 0.931
M07.30 Other psoriatic arthropathies (Multiple sites)
0.930 0.070 0.000
F60-F69 Disorders of adult personality and behaviour
0.929 0.071 0.000
M07.3 Other psoriatic arthropathies
0.928 0.072 0.000
L40.8 Other psoriasis
0.926 0.074 0.000
F40 Phobic anxiety disorders
0.922 0.078 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.922 0.078 0.000
E16.2 Hypoglycaemia, unspecified
0.000 0.086 0.914
F60 Specific personality disorders
0.903 0.097 0.000
E10.5 With peripheral circulatory complications
0.000 0.100 0.900
F52 Sexual dysfunction, not caused by organic disorder or disease
0.897 0.103 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.880 0.120 0.000
L40.1 Generalised pustular psoriasis
0.868 0.131 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.867 0.133 0.000
F40.2 Specific (isolated) phobias
0.867 0.133 0.000
F52.2 Failure of genital response
0.864 0.136 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.859 0.141 0.000
F34 Persistent mood [affective] disorders
0.845 0.155 0.000
E10.6 With other specified complications
0.000 0.157 0.843
E07 Other disorders of thyroid
0.000 0.158 0.842
F48 Other neurotic disorders
0.835 0.165 0.000
F60.3 Emotionally unstable personality disorder
0.833 0.167 0.000
E10.0 With coma
0.000 0.177 0.823
F41 Other anxiety disorders
0.823 0.177 0.000
E10.2 With renal complications
0.000 0.188 0.812
F44 Dissociative [conversion] disorders
0.810 0.190 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.805 0.195 0.000
F41.2 Mixed anxiety and depressive disorder
0.801 0.199 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.793 0.207 0.000
F32 Depressive episode
0.790 0.210 0.000
F30 Manic episode
0.781 0.219 0.000
F60.5 Anankastic personality disorder
0.779 0.221 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.776 0.224 0.000
E07.9 Disorder of thyroid, unspecified
0.000 0.234 0.766
F40.9 Phobic anxiety disorder, unspecified
0.765 0.235 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.762 0.238 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.238 0.762
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.238 0.762
F50 Eating disorders
0.759 0.241 0.000
F43 Reaction to severe stress, and adjustment disorders
0.757 0.243 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.749 0.251 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.746 0.254 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.744 0.256 0.000
E50-E64 Other nutritional deficiencies
0.000 0.257 0.743
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.261 0.739
F34.1 Dysthymia
0.738 0.262 0.000
F33.0 Recurrent depressive disorder, current episode mild
0.737 0.263 0.000
F60.7 Dependent personality disorder
0.734 0.266 0.000
F70-F79 Mental retardation
0.732 0.268 0.000
F31.7 Bipolar affective disorder, currently in remission
0.725 0.275 0.000
E06 Thyroiditis
0.000 0.276 0.723
E10.8 With unspecified complications
0.000 0.281 0.719
E10.7 With multiple complications
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.717 0.283 0.000
L40.3 Pustulosis palmaris et plantaris
0.717 0.283 0.000
L40.2 Acrodermatitis continua
0.717 0.283 0.000
E05.8 Other thyrotoxicosis
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
F32.0 Mild depressive episode
0.717 0.283 0.000
E03.5 Myxoedema coma
0.000 0.284 0.716
E03.4 Atrophy of thyroid (acquired)
0.000 0.284 0.716
E03.3 Postinfectious hypothyroidism
0.000 0.284 0.716
E03.1 Congenital hypothyroidism without goitre
0.000 0.284 0.716
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.284 0.716
F33.8 Other recurrent depressive disorders
0.713 0.287 0.000
F33.4 Recurrent depressive disorder, currently in remission
0.713 0.287 0.000
F38 Other mood [affective] disorders
0.713 0.287 0.000
F48.0 Neurasthenia
0.707 0.293 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.706 0.294 0.000
E12 Malnutrition-related diabetes mellitus
0.000 0.295 0.705
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.698 0.302 0.000
F31.8 Other bipolar affective disorders
0.691 0.309 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.689 0.310 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.687 0.313 0.000
F43.2 Adjustment disorders
0.685 0.315 0.000
F51 Nonorganic sleep disorders
0.684 0.316 0.000
F31.9 Bipolar affective disorder, unspecified
0.684 0.316 0.000
E15 Nondiabetic hypoglycaemic coma
0.000 0.317 0.683
F44.9 Dissociative [conversion] disorder, unspecified
0.682 0.318 0.000
F39 Unspecified mood [affective] disorder
0.679 0.321 0.000
F60.9 Personality disorder, unspecified
0.678 0.322 0.000
F53 Mental and behavioural disorders associated with the puerperium, not elsewhere classified
0.675 0.325 0.000
F59 Unspecified behavioural syndromes associated with physiological disturbances and physical factors
0.675 0.325 0.000
F55 Abuse of non-dependence-producing substances
0.675 0.325 0.000
F54 Psychological and behavioural factors associated with disorders or diseases classified elsewhere
0.675 0.325 0.000
F40.8 Other phobic anxiety disorders
0.674 0.326 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.330 0.669
F42 Obsessive-compulsive disorder
0.668 0.332 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.332 0.667
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.332 0.667
E16.4 Abnormal secretion of gastrin
0.000 0.332 0.667
E16.3 Increased secretion of glucagon
0.000 0.332 0.667
F68 Other disorders of adult personality and behaviour
0.666 0.334 0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation
0.666 0.334 0.000
F65 Disorders of sexual preference
0.666 0.334 0.000
F63 Habit and impulse disorders
0.666 0.334 0.000
F62 Enduring personality changes, not attributable to brain damage and disease
0.666 0.334 0.000
F61 Mixed and other personality disorders
0.666 0.334 0.000
M07.38 Other psoriatic arthropathies (Other)
0.665 0.334 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.665 0.334 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.665 0.334 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.665 0.334 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.665 0.334 0.000
F60.6 Anxious [avoidant] personality disorder
0.664 0.336 0.000
F40.1 Social phobias
0.661 0.339 0.000
F48.9 Neurotic disorder, unspecified
0.657 0.342 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.656 0.344 0.000
E03.8 Other specified hypothyroidism
0.000 0.346 0.654
F30.1 Mania without psychotic symptoms
0.652 0.348 0.000
F30.2 Mania with psychotic symptoms
0.648 0.352 0.000
F60.8 Other specific personality disorders
0.647 0.352 0.000
F60.4 Histrionic personality disorder
0.647 0.352 0.000
F60.2 Dissocial personality disorder
0.647 0.352 0.000
F60.1 Schizoid personality disorder
0.647 0.352 0.000
F60.0 Paranoid personality disorder
0.647 0.352 0.000
F69 Unspecified disorder of adult personality and behaviour
0.647 0.353 0.000
F52.9 Unspecified sexual dysfunction, not caused by organic disorder or disease
0.643 0.357 0.000
F52.8 Other sexual dysfunction, not caused by organic disorder or disease
0.643 0.357 0.000
F52.7 Excessive sexual drive
0.643 0.357 0.000
F52.6 Nonorganic dyspareunia
0.643 0.357 0.000
F52.5 Nonorganic vaginismus
0.643 0.357 0.000
F52.4 Premature ejaculation
0.643 0.357 0.000
F52.3 Orgasmic dysfunction
0.643 0.357 0.000
F52.1 Sexual aversion and lack of sexual enjoyment
0.643 0.357 0.000
F52.0 Lack or loss of sexual desire
0.643 0.357 0.000
F40.0 Agoraphobia
0.633 0.366 0.000
F22 Persistent delusional disorders
0.628 0.372 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.618 0.382 0.000
E55 Vitamin D deficiency
0.000 0.391 0.609
F34.9 Persistent mood [affective] disorder, unspecified
0.606 0.394 0.000
F34.8 Other persistent mood [affective] disorders
0.606 0.394 0.000
F34.0 Cyclothymia
0.606 0.394 0.000
E07.1 Dyshormogenetic goitre
0.000 0.396 0.604
E07.0 Hypersecretion of calcitonin
0.000 0.396 0.604
F32.1 Moderate depressive episode
0.604 0.396 0.000
F25 Schizoaffective disorders
0.604 0.396 0.000
F50.9 Eating disorder, unspecified
0.604 0.396 0.000
F44.5 Dissociative convulsions
0.603 0.397 0.000
F48.8 Other specified neurotic disorders
0.599 0.401 0.000
F48.1 Depersonalisation-derealisation syndrome
0.599 0.401 0.000
F23 Acute and transient psychotic disorders
0.596 0.404 0.000
E13 Other specified diabetes mellitus
0.000 0.405 0.595
F41.8 Other specified anxiety disorders
0.590 0.410 0.000
F41.3 Other mixed anxiety disorders
0.590 0.410 0.000
F41.9 Anxiety disorder, unspecified
0.585 0.415 0.000
F44.8 Other dissociative [conversion] disorders
0.580 0.419 0.000
F44.7 Mixed dissociative [conversion] disorders
0.580 0.419 0.000
F44.6 Dissociative anaesthesia and sensory loss
0.580 0.419 0.000
F44.4 Dissociative motor disorders
0.580 0.419 0.000
F44.3 Trance and possession disorders
0.580 0.419 0.000
F44.2 Dissociative stupor
0.580 0.419 0.000
F44.1 Dissociative fugue
0.580 0.419 0.000
F44.0 Dissociative amnesia
0.580 0.419 0.000
F50.0 Anorexia nervosa
0.578 0.422 0.000
F99-F99 Unspecified mental disorder
0.574 0.426 0.000
F43.9 Reaction to severe stress, unspecified
0.568 0.432 0.000
F32.8 Other depressive episodes
0.563 0.437 0.000
F30.8 Other manic episodes
0.560 0.440 0.000
E06.3 Autoimmune thyroiditis
0.000 0.440 0.560
E16.1 Other hypoglycaemia
0.000 0.445 0.555
F64 Gender identity disorders
0.553 0.447 0.000
F79 Unspecified mental retardation
0.551 0.449 0.000
F80-F89 Disorders of psychological development
0.549 0.451 0.000
F50.8 Other eating disorders
0.544 0.456 0.000
F50.5 Vomiting associated with other psychological disturbances
0.544 0.456 0.000
F50.4 Overeating associated with other psychological disturbances
0.544 0.456 0.000
F50.3 Atypical bulimia nervosa
0.544 0.456 0.000
F50.1 Atypical anorexia nervosa
0.544 0.456 0.000
F43.8 Other reactions to severe stress
0.543 0.457 0.000
F50.2 Bulimia nervosa
0.543 0.457 0.000
F22.0 Delusional disorder
0.542 0.458 0.000
F28 Other nonorganic psychotic disorders
0.537 0.463 0.000
F24 Induced delusional disorder
0.537 0.463 0.000
F21 Schizotypal disorder
0.537 0.463 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.536 0.464 0.000
F45 Somatoform disorders
0.534 0.466 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.467 0.532
E63 Other nutritional deficiencies
0.000 0.467 0.532
E56 Other vitamin deficiencies
0.000 0.467 0.532
E51 Thiamine deficiency
0.000 0.467 0.532
E50 Vitamin A deficiency
0.000 0.467 0.532
E60 Dietary zinc deficiency
0.000 0.467 0.532
E59 Dietary selenium deficiency
0.000 0.467 0.532
E58 Dietary calcium deficiency
0.000 0.467 0.532
E54 Ascorbic acid deficiency
0.000 0.467 0.532
E52 Niacin deficiency [pellagra]
0.000 0.467 0.532
E61 Deficiency of other nutrient elements
0.000 0.471 0.529
F78 Other mental retardation
0.525 0.475 0.000
F73 Profound mental retardation
0.525 0.475 0.000
F72 Severe mental retardation
0.525 0.475 0.000
F71 Moderate mental retardation
0.525 0.475 0.000
F70 Mild mental retardation
0.525 0.475 0.000
E06.5 Other chronic thyroiditis
0.000 0.481 0.519
E06.4 Drug-induced thyroiditis
0.000 0.481 0.519
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.481 0.519
E06.1 Subacute thyroiditis
0.000 0.481 0.519
E06.0 Acute thyroiditis
0.000 0.481 0.519
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E55.9 Vitamin D deficiency, unspecified
0.000 0.486 0.514
F42.0 Predominantly obsessional thoughts or ruminations
0.513 0.487 0.000
F38.8 Other specified mood [affective] disorders
0.511 0.489 0.000
F38.1 Other recurrent mood [affective] disorders
0.511 0.489 0.000
F38.0 Other single mood [affective] disorders
0.511 0.489 0.000
E40-E46 Malnutrition
0.001 0.490 0.509
F98 Other behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.506 0.494 0.000
F95 Tic disorders
0.506 0.494 0.000
F94 Disorders of social functioning with onset specific to childhood and adolescence
0.506 0.494 0.000
F93 Emotional disorders with onset specific to childhood
0.506 0.494 0.000
F92 Mixed disorders of conduct and emotions
0.506 0.494 0.000
F91 Conduct disorders
0.506 0.494 0.000
F90 Hyperkinetic disorders
0.506 0.494 0.000
E12.9 Without complications
0.000 0.494 0.505
E12.8 With unspecified complications
0.000 0.494 0.505
E12.7 With multiple complications
0.000 0.494 0.505
E12.6 With other specified complications
0.000 0.494 0.505
E12.5 With peripheral circulatory complications
0.000 0.494 0.505
E12.4 With neurological complications
0.000 0.494 0.505
E12.3 With ophthalmic complications
0.000 0.494 0.505
E12.2 With renal complications
0.000 0.494 0.505
E12.1 With ketoacidosis
0.000 0.494 0.505
E12.0 With coma
0.000 0.494 0.505
F23.0 Acute polymorphic psychotic disorder without symptoms of schizophrenia
0.502 0.498 0.000
F51.0 Nonorganic insomnia
0.499 0.501 0.000
E07.8 Other specified disorders of thyroid
0.000 0.508 0.492
F00-F09 Organic, including symptomatic, mental disorders
0.492 0.508 0.000
F51.9 Nonorganic sleep disorder, unspecified
0.490 0.510 0.000
F51.8 Other nonorganic sleep disorders
0.490 0.510 0.000
F51.5 Nightmares
0.490 0.510 0.000
F51.4 Sleep terrors [night terrors]
0.490 0.510 0.000
F51.3 Sleepwalking [somnambulism]
0.490 0.510 0.000
F51.2 Nonorganic disorder of the sleep-wake schedule
0.490 0.510 0.000
F51.1 Nonorganic hypersomnia
0.490 0.510 0.000
F25.9 Schizoaffective disorder, unspecified
0.489 0.511 0.000
F53.9 Puerperal mental disorder, unspecified
0.484 0.516 0.000
F53.8 Other mental and behavioural disorders associated with the puerperium, not elsewhere classified
0.484 0.516 0.000
F53.1 Severe mental and behavioural disorders associated with the puerperium, not elsewhere classified
0.484 0.516 0.000
F53.0 Mild mental and behavioural disorders associated with the puerperium, not elsewhere classified
0.484 0.516 0.000
F25.0 Schizoaffective disorder, manic type
0.482 0.518 0.000
F30.0 Hypomania
0.479 0.521 0.000
F42.8 Other obsessive-compulsive disorders
0.479 0.521 0.000
F42.2 Mixed obsessional thoughts and acts
0.479 0.521 0.000
F42.1 Predominantly compulsive acts [obsessional rituals]
0.479 0.521 0.000
F62.9 Enduring personality change, unspecified
0.477 0.522 0.000
F62.8 Other enduring personality changes
0.477 0.522 0.000
F62.1 Enduring personality change after psychiatric illness
0.477 0.522 0.000
F62.0 Enduring personality change after catastrophic experience
0.477 0.522 0.000
F63.9 Habit and impulse disorder, unspecified
0.477 0.522 0.000
F63.8 Other habit and impulse disorders
0.477 0.522 0.000
F63.3 Trichotillomania
0.477 0.522 0.000
F63.2 Pathological stealing [kleptomania]
0.477 0.522 0.000
F63.1 Pathological fire-setting [pyromania]
0.477 0.522 0.000
F63.0 Pathological gambling
0.477 0.522 0.000
F65.9 Disorder of sexual preference, unspecified
0.477 0.522 0.000
F65.8 Other disorders of sexual preference
0.477 0.522 0.000
F65.6 Multiple disorders of sexual preference
0.477 0.522 0.000
F65.5 Sadomasochism
0.477 0.522 0.000
F65.4 Paedophilia
0.477 0.522 0.000
F65.3 Voyeurism
0.477 0.522 0.000
F65.2 Exhibitionism
0.477 0.522 0.000
F65.1 Fetishistic transvestism
0.477 0.522 0.000
F65.0 Fetishism
0.477 0.522 0.000
F66.9 Psychosexual development disorder, unspecified
0.477 0.522 0.000
F66.8 Other psychosexual development disorders
0.477 0.522 0.000
F66.2 Sexual relationship disorder
0.477 0.522 0.000
F66.1 Egodystonic sexual orientation
0.477 0.522 0.000
F66.0 Sexual maturation disorder
0.477 0.522 0.000
F68.8 Other specified disorders of adult personality and behaviour
0.477 0.522 0.000
F68.1 Intentional production or feigning of symptoms or disabilities, either physical or psychological [factitious disorder]
0.477 0.522 0.000
F68.0 Elaboration of physical symptoms for psychological reasons
0.477 0.522 0.000
F23.3 Other acute predominantly delusional psychotic disorders
0.477 0.523 0.000
E06.9 Thyroiditis, unspecified
0.000 0.524 0.476
E53 Deficiency of other B group vitamins
0.000 0.525 0.475
F12 Mental and behavioural disorders due to use of cannabinoids
0.461 0.538 0.000
F30.9 Manic episode, unspecified
0.460 0.539 0.000
F43.0 Acute stress reaction
0.460 0.540 0.000
F22.9 Persistent delusional disorder, unspecified
0.450 0.549 0.000
F22.8 Other persistent delusional disorders
0.450 0.549 0.000
E55.0 Rickets, active
0.000 0.563 0.437
F11 Mental and behavioural disorders due to use of opioids
0.434 0.566 0.000
E65-E68 Obesity and other hyperalimentation
0.000 0.566 0.434
F25.8 Other schizoaffective disorders
0.433 0.567 0.000
F25.2 Schizoaffective disorder, mixed type
0.433 0.567 0.000
F23.8 Other acute and transient psychotic disorders
0.427 0.572 0.000
F23.2 Acute schizophrenia-like psychotic disorder
0.427 0.572 0.000
F23.1 Acute polymorphic psychotic disorder with symptoms of schizophrenia
0.427 0.572 0.000
E13.8 With unspecified complications
0.000 0.573 0.427
E13.7 With multiple complications
0.000 0.573 0.427
E13.6 With other specified complications
0.000 0.573 0.427
E13.5 With peripheral circulatory complications
0.000 0.573 0.427
E13.4 With neurological complications
0.000 0.573 0.427
E13.3 With ophthalmic complications
0.000 0.573 0.427
E13.2 With renal complications
0.000 0.573 0.427
E13.1 With ketoacidosis
0.000 0.573 0.427
E13.0 With coma
0.000 0.573 0.427
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.424 0.576 0.000
M07 Psoriatic and enteropathic arthropathies
0.424 0.576 0.000
F79.9 Unspecified mental retardation (Without mention of impairment of behaviour)
0.422 0.578 0.000
F12.1 Harmful use
0.419 0.581 0.000
K90 Intestinal malabsorption
0.000 0.585 0.415
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.408 0.592 0.000
E61.2 Magnesium deficiency
0.000 0.594 0.406
F45.2 Hypochondriacal disorder
0.404 0.595 0.000
F42.9 Obsessive-compulsive disorder, unspecified
0.404 0.596 0.000
F20 Schizophrenia
0.402 0.598 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.398 0.602 0.000
F64.9 Gender identity disorder, unspecified
0.396 0.603 0.000
F64.8 Other gender identity disorders
0.396 0.603 0.000
F64.2 Gender identity disorder of childhood
0.396 0.603 0.000
F64.1 Dual-role transvestism
0.396 0.603 0.000
F79.8 Unspecified mental retardation (Other impairments of behaviour)
0.395 0.604 0.000
F79.1 Unspecified mental retardation (Significant impairment of behaviour requiring attention or treatment)
0.395 0.604 0.000
F79.0 Unspecified mental retardation (With the statement of no, or minimal, impairment of behaviour)
0.395 0.604 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.394 0.606 0.000
F89 Unspecified disorder of psychological development
0.394 0.606 0.000
F88 Other disorders of psychological development
0.394 0.606 0.000
F83 Mixed specific developmental disorders
0.394 0.606 0.000
F82 Specific developmental disorder of motor function
0.394 0.606 0.000
F43.1 Posttraumatic stress disorder
0.390 0.609 0.000
F45.9 Somatoform disorder, unspecified
0.390 0.610 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.390 0.610 0.000
F25.1 Schizoaffective disorder, depressive type
0.387 0.613 0.000
T43.2 Other and unspecified antidepressants
0.386 0.614 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.385 0.615 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.385 0.615 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.385 0.615 0.000
F45.4 Persistent somatoform pain disorder
0.383 0.617 0.000
F45.1 Undifferentiated somatoform disorder
0.383 0.617 0.000
F45.0 Somatisation disorder
0.383 0.617 0.000
F29 Unspecified nonorganic psychosis
0.383 0.617 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.382 0.618 0.000
E50.9 Vitamin A deficiency, unspecified
0.000 0.618 0.382
E50.8 Other manifestations of vitamin A deficiency
0.000 0.618 0.382
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.618 0.382
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.618 0.382
E50.5 Vitamin A deficiency with night blindness
0.000 0.618 0.382
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.618 0.382
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.618 0.382
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.618 0.382
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.618 0.382
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.618 0.382
E51.9 Thiamine deficiency, unspecified
0.000 0.618 0.382
E51.8 Other manifestations of thiamine deficiency
0.000 0.618 0.382
E51.2 Wernicke's encephalopathy
0.000 0.618 0.382
E51.1 Beriberi
0.000 0.618 0.382
E56.9 Vitamin deficiency, unspecified
0.000 0.618 0.382
E56.8 Deficiency of other vitamins
0.000 0.618 0.382
E56.1 Deficiency of vitamin K
0.000 0.618 0.382
E56.0 Deficiency of vitamin E
0.000 0.618 0.382
E63.9 Nutritional deficiency, unspecified
0.000 0.618 0.382
E63.8 Other specified nutritional deficiencies
0.000 0.618 0.382
E63.1 Imbalance of constituents of food intake
0.000 0.618 0.382
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.618 0.382
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.618 0.382
E64.8 Sequelae of other nutritional deficiencies
0.000 0.618 0.382
E64.3 Sequelae of rickets
0.000 0.618 0.382
E64.2 Sequelae of vitamin C deficiency
0.000 0.618 0.382
E64.1 Sequelae of vitamin A deficiency
0.000 0.618 0.382
E64.0 Sequelae of protein-energy malnutrition
0.000 0.618 0.382
F84 Pervasive developmental disorders
0.379 0.620 0.000
E61.9 Deficiency of nutrient element, unspecified
0.000 0.620 0.380
E61.8 Deficiency of other specified nutrient elements
0.000 0.620 0.380
E61.7 Deficiency of multiple nutrient elements
0.000 0.620 0.380
E61.6 Vanadium deficiency
0.000 0.620 0.380
E61.5 Molybdenum deficiency
0.000 0.620 0.380
E61.4 Chromium deficiency
0.000 0.620 0.380
E61.3 Manganese deficiency
0.000 0.620 0.380
E61.0 Copper deficiency
0.000 0.620 0.380
F45.3 Somatoform autonomic dysfunction
0.379 0.620 0.000
F70.9 Mild mental retardation (Without mention of impairment of behaviour)
0.376 0.623 0.000
F70.8 Mild mental retardation (Other impairments of behaviour)
0.376 0.623 0.000
F70.1 Mild mental retardation (Significant impairment of behaviour requiring attention or treatment)
0.376 0.623 0.000
F70.0 Mild mental retardation (With the statement of no, or minimal, impairment of behaviour)
0.376 0.623 0.000
F71.9 Moderate mental retardation (Without mention of impairment of behaviour)
0.376 0.623 0.000
F71.8 Moderate mental retardation (Other impairments of behaviour)
0.376 0.623 0.000
F71.1 Moderate mental retardation (Significant impairment of behaviour requiring attention or treatment)
0.376 0.623 0.000
F71.0 Moderate mental retardation (With the statement of no, or minimal, impairment of behaviour)
0.376 0.623 0.000
F72.9 Severe mental retardation (Without mention of impairment of behaviour)
0.376 0.623 0.000
F72.8 Severe mental retardation (Other impairments of behaviour)
0.376 0.623 0.000
F72.1 Severe mental retardation (Significant impairment of behaviour requiring attention or treatment)
0.376 0.623 0.000
F72.0 Severe mental retardation (With the statement of no, or minimal, impairment of behaviour)
0.376 0.623 0.000
F73.9 Profound mental retardation (Without mention of impairment of behaviour)
0.376 0.623 0.000
F73.8 Profound mental retardation (Other impairments of behaviour)
0.376 0.623 0.000
F73.1 Profound mental retardation (Significant impairment of behaviour requiring attention or treatment)
0.376 0.623 0.000
F73.0 Profound mental retardation (With the statement of no, or minimal, impairment of behaviour)
0.376 0.623 0.000
F78.9 Other mental retardation (Without mention of impairment of behaviour)
0.376 0.623 0.000
F78.8 Other mental retardation (Other impairments of behaviour)
0.376 0.623 0.000
F78.1 Other mental retardation (Significant impairment of behaviour requiring attention or treatment)
0.376 0.623 0.000
F78.0 Other mental retardation (With the statement of no, or minimal, impairment of behaviour)
0.376 0.623 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.373 0.627 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.370 0.630 0.000
F41.1 Generalised anxiety disorder
0.369 0.630 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.001 0.634 0.365
E45 Retarded development following protein-energy malnutrition
0.001 0.634 0.365
E43 Unspecified severe protein-energy malnutrition
0.001 0.634 0.365
E42 Marasmic kwashiorkor
0.001 0.634 0.365
E41 Nutritional marasmus
0.001 0.634 0.365
E40 Kwashiorkor
0.001 0.634 0.365
F81 Specific developmental disorders of scholastic skills
0.364 0.636 0.000
F90.9 Hyperkinetic disorder, unspecified
0.363 0.637 0.000
F90.8 Other hyperkinetic disorders
0.363 0.637 0.000
F90.1 Hyperkinetic conduct disorder
0.363 0.637 0.000
F90.0 Disturbance of activity and attention
0.363 0.637 0.000
F91.9 Conduct disorder, unspecified
0.363 0.637 0.000
F91.8 Other conduct disorders
0.363 0.637 0.000
F91.3 Oppositional defiant disorder
0.363 0.637 0.000
F91.2 Socialised conduct disorder
0.363 0.637 0.000
F91.1 Unsocialised conduct disorder
0.363 0.637 0.000
F91.0 Conduct disorder confined to the family context
0.363 0.637 0.000
F92.9 Mixed disorder of conduct and emotions, unspecified
0.363 0.637 0.000
F92.8 Other mixed disorders of conduct and emotions
0.363 0.637 0.000
F92.0 Depressive conduct disorder
0.363 0.637 0.000
F93.9 Childhood emotional disorder, unspecified
0.363 0.637 0.000
F93.8 Other childhood emotional disorders
0.363 0.637 0.000
F93.3 Sibling rivalry disorder
0.363 0.637 0.000
F93.2 Social anxiety disorder of childhood
0.363 0.637 0.000
F93.1 Phobic anxiety disorder of childhood
0.363 0.637 0.000
F93.0 Separation anxiety disorder of childhood
0.363 0.637 0.000
F94.9 Childhood disorder of social functioning, unspecified
0.363 0.637 0.000
F94.8 Other childhood disorders of social functioning
0.363 0.637 0.000
F94.2 Disinhibited attachment disorder of childhood
0.363 0.637 0.000
F94.1 Reactive attachment disorder of childhood
0.363 0.637 0.000
F94.0 Elective mutism
0.363 0.637 0.000
F95.9 Tic disorder, unspecified
0.363 0.637 0.000
F95.8 Other tic disorders
0.363 0.637 0.000
F95.2 Combined vocal and multiple motor tic disorder [de la Tourette]
0.363 0.637 0.000
F95.1 Chronic motor or vocal tic disorder
0.363 0.637 0.000
F95.0 Transient tic disorder
0.363 0.637 0.000
F98.9 Unspecified behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.363 0.637 0.000
F98.8 Other specified behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.363 0.637 0.000
F98.6 Cluttering
0.363 0.637 0.000
F98.5 Stuttering [stammering]
0.363 0.637 0.000
F98.4 Stereotyped movement disorders
0.363 0.637 0.000
F98.3 Pica of infancy and childhood
0.363 0.637 0.000
F98.2 Feeding disorder of infancy and childhood
0.363 0.637 0.000
F98.1 Nonorganic encopresis
0.363 0.637 0.000
F98.0 Nonorganic enuresis
0.363 0.637 0.000
F02 Dementia in other diseases classified elsewhere
0.362 0.638 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.361 0.639 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.361 0.639 0.000
F09 Unspecified organic or symptomatic mental disorder
0.353 0.647 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.353 0.647 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.351 0.649 0.000
E61.1 Iron deficiency
0.000 0.656 0.344
F19.1 Harmful use
0.343 0.656 0.000
F11.1 Harmful use
0.343 0.657 0.000
E53.9 Vitamin B deficiency, unspecified
0.000 0.659 0.341
E53.1 Pyridoxine deficiency
0.000 0.659 0.341
E53.0 Riboflavin deficiency
0.000 0.659 0.341
K90.9 Intestinal malabsorption, unspecified
0.000 0.663 0.337
F11.2 Dependence syndrome
0.336 0.664 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.335 0.665 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.332 0.668 0.000
F12.9 Unspecified mental and behavioural disorder
0.331 0.669 0.000
F12.8 Other mental and behavioural disorders
0.331 0.669 0.000
F12.7 Residual and late-onset psychotic disorder
0.331 0.669 0.000
F12.6 Amnesic syndrome
0.331 0.669 0.000
F12.5 Psychotic disorder
0.331 0.669 0.000
F12.4 Withdrawal state with delirium
0.331 0.669 0.000
F12.3 Withdrawal state
0.331 0.669 0.000
F12.0 Acute intoxication
0.331 0.669 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.330 0.670 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.329 0.671 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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