TreeWAS – Variant ID: rs12195582

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	1.000	0.000	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	1.000	0.000	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	1.000	0.000	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	1.000	0.000	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	1.000	0.000	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	1.000	0.000	0.000
E10.9 Without complications	1.000	0.000	0.000
E10.3 With ophthalmic complications	1.000	0.000	0.000
E11.9 Without complications	1.000	0.000	0.000
J33.9 Nasal polyp, unspecified	1.000	0.000	0.000
J45.9 Asthma, unspecified	1.000	0.000	0.000
K90.0 Coeliac disease	0.000	0.000	1.000
L40.9 Psoriasis, unspecified	1.000	0.000	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	1.000	0.000	0.000
M06.9 Rheumatoid arthritis, unspecified	1.000	0.000	0.000
E11 Non-insulin-dependent diabetes mellitus	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
G35 Multiple sclerosis	0.000	0.000	1.000
L40 Psoriasis	1.000	0.000	0.000
M06 Other rheumatoid arthritis	1.000	0.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
M05-M14 Inflammatory polyarthropathies	1.000	0.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	1.000	0.000	0.000
J33 Nasal polyp	1.000	0.000	0.000
Chapter X Diseases of the respiratory system	1.000	0.000	0.000
M05 Seropositive rheumatoid arthritis	1.000	0.000	0.000
L40-L45 Papulosquamous disorders	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
E10.1 With ketoacidosis	1.000	0.000	0.000
M06.0 Seronegative rheumatoid arthritis	1.000	0.000	0.000
D86 Sarcoidosis	0.000	0.000	1.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	1.000	0.000	0.000
M06.3 Rheumatoid nodule	1.000	0.000	0.000
J30-J39 Other diseases of upper respiratory tract	1.000	0.000	0.000
D86.0 Sarcoidosis of lung	0.000	0.000	1.000
J40-J47 Chronic lower respiratory diseases	1.000	0.000	0.000
J45 Asthma	1.000	0.000	0.000
D80-D89 Certain disorders involving the immune mechanism	0.000	0.000	1.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.999	0.001	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.001	0.999
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.999	0.001	0.000
L40.5 Arthropathic psoriasis	0.999	0.001	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.001	0.999
E10.4 With neurological complications	0.998	0.002	0.000
M07 Psoriatic and enteropathic arthropathies	0.998	0.002	0.000
E03.9 Hypothyroidism, unspecified	0.998	0.002	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.000	0.003	0.997
J32 Chronic sinusitis	0.997	0.003	0.000
M07.3 Other psoriatic arthropathies	0.997	0.003	0.000
E03 Other hypothyroidism	0.996	0.003	0.000
E00-E07 Disorders of thyroid gland	0.996	0.003	0.001
M35.3 Polymyalgia rheumatica	0.996	0.004	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.996	0.004	0.000
M20-M25 Other joint disorders	0.995	0.005	0.000
J32.9 Chronic sinusitis, unspecified	0.994	0.006	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.994	0.006	0.000
M06.34 Rheumatoid nodule (Hand)	0.994	0.006	0.000
D68 Other coagulation defects	0.000	0.007	0.993
M35 Other systemic involvement of connective tissue	0.993	0.007	0.000
L43 Lichen planus	0.993	0.007	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.992	0.008	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.991	0.009	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.989	0.011	0.000
H91.9 Hearing loss, unspecified	0.985	0.015	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.000	0.016	0.984
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.983	0.017	0.000
E14 Unspecified diabetes mellitus	0.980	0.020	0.000
L00-L08 Infections of the skin and subcutaneous tissue	0.980	0.020	0.000
L43.9 Lichen planus, unspecified	0.979	0.021	0.000
H91 Other hearing loss	0.979	0.021	0.000
M65-M68 Disorders of synovium and tendon	0.979	0.021	0.000
M45-M49 Spondylopathies	0.978	0.022	0.000
M31 Other necrotising vasculopathies	0.978	0.022	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.976	0.024	0.000
E11.1 With ketoacidosis	0.976	0.024	0.000
M45 Ankylosing spondylitis	0.975	0.025	0.000
E10.5 With peripheral circulatory complications	0.975	0.025	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.032	0.026	0.941
Chapter VIII Diseases of the ear and mastoid process	0.973	0.027	0.000
H90-H95 Other disorders of ear	0.973	0.027	0.000
E16 Other disorders of pancreatic internal secretion	0.971	0.029	0.000
M65 Synovitis and tenosynovitis	0.971	0.029	0.000
J46 Status asthmaticus	0.970	0.030	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.969	0.031	0.000
D86.9 Sarcoidosis, unspecified	0.000	0.032	0.968
M65.9 Synovitis and tenosynovitis, unspecified	0.966	0.034	0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.965	0.035	0.000
E16.2 Hypoglycaemia, unspecified	0.964	0.036	0.000
L02 Cutaneous abscess, furuncle and carbuncle	0.961	0.039	0.000
M31.6 Other giant cell arteritis	0.955	0.045	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.000	0.048	0.952
M06.37 Rheumatoid nodule (Ankle and foot)	0.952	0.048	0.000
E10.8 With unspecified complications	0.945	0.055	0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.944	0.056	0.000
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock	0.942	0.058	0.000
E10.6 With other specified complications	0.942	0.058	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.941	0.059	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.940	0.060	0.000
J33.8 Other polyp of sinus	0.938	0.062	0.000
M06.4 Inflammatory polyarthropathy	0.938	0.062	0.000
E05.9 Thyrotoxicosis, unspecified	0.000	0.063	0.937
J43 Emphysema	0.937	0.063	0.000
D50-D53 Nutritional anaemias	0.000	0.063	0.937
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.932	0.068	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.931	0.069	0.000
D68.8 Other specified coagulation defects	0.000	0.072	0.928
J35 Chronic diseases of tonsils and adenoids	0.925	0.075	0.000
J33.0 Polyp of nasal cavity	0.922	0.078	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.918	0.082	0.000
E11.5 With peripheral circulatory complications	0.915	0.085	0.000
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)	0.914	0.086	0.000
D68.5 Primary Thrombophilia	0.000	0.086	0.914
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.914	0.086	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.913	0.087	0.000
E10.2 With renal complications	0.911	0.089	0.000
E11.4 With neurological complications	0.910	0.090	0.000
J32.4 Chronic pansinusitis	0.901	0.099	0.000
M00-M03 Infectious arthropathies	0.899	0.101	0.000
L05 Pilonidal cyst	0.896	0.104	0.000
D52 Folate deficiency anaemia	0.000	0.104	0.896
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.896	0.104	0.000
D69 Purpura and other haemorrhagic conditions	0.000	0.106	0.894
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.893	0.107	0.000
D68.2 Hereditary deficiency of other clotting factors	0.000	0.117	0.883
D86.1 Sarcoidosis of lymph nodes	0.000	0.119	0.881
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.881	0.119	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.880	0.120	0.000
J43.9 Emphysema, unspecified	0.880	0.120	0.000
E14.3 With ophthalmic complications	0.877	0.123	0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck	0.876	0.124	0.000
M30 Polyarteritis nodosa and related conditions	0.872	0.128	0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)	0.870	0.130	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.868	0.132	0.000
L02.0 Cutaneous abscess, furuncle and carbuncle of face	0.868	0.132	0.000
D51 Vitamin B12 deficiency anaemia	0.000	0.132	0.868
D52.9 Folate deficiency anaemia, unspecified	0.000	0.134	0.866
C82.0 Small cleaved cell, follicular	0.865	0.135	0.000
L43.8 Other lichen planus	0.865	0.135	0.000
J35.8 Other chronic diseases of tonsils and adenoids	0.865	0.135	0.000
M05.8 Other seropositive rheumatoid arthritis	0.863	0.137	0.000
L05.0 Pilonidal cyst with abscess	0.860	0.140	0.000
M14 Arthropathies in other diseases classified elsewhere	0.859	0.141	0.000
M25 Other joint disorders, not elsewhere classified	0.858	0.142	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.000	0.144	0.856
E14.6 With other specified complications	0.847	0.153	0.000
D55-D59 Haemolytic anaemias	0.000	0.155	0.845
E10.0 With coma	0.845	0.155	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.841	0.159	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.839	0.160	0.000
M25.4 Effusion of joint	0.839	0.161	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.838	0.162	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.006	0.164	0.830
J35.1 Hypertrophy of tonsils	0.836	0.164	0.000
M34 Systemic sclerosis	0.834	0.166	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.000	0.168	0.832
M25.46 Effusion of joint (Lower leg)	0.832	0.168	0.000
C82.3 Follicular lymphoma grade IIIa	0.830	0.170	0.000
M46 Other inflammatory spondylopathies	0.830	0.170	0.000
M06.33 Rheumatoid nodule (Forearm)	0.827	0.173	0.000
D68.1 Hereditary factor XI deficiency	0.000	0.174	0.826
H91.1 Presbycusis	0.825	0.175	0.000
M05.1 Rheumatoid lung disease	0.824	0.176	0.000
E11.0 With coma	0.817	0.183	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.815	0.185	0.000
E78.0 Pure hypercholesterolaemia	0.813	0.187	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.813	0.187	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.811	0.189	0.000
D86.3 Sarcoidosis of skin	0.000	0.190	0.810
E13 Other specified diabetes mellitus	0.810	0.190	0.000
M00 Pyogenic arthritis	0.809	0.191	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.809	0.191	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.807	0.193	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.804	0.196	0.000
M31.7 Microscopic polyangiitis	0.802	0.198	0.000
D68.9 Coagulation defect, unspecified	0.000	0.199	0.801
G37 Other demyelinating diseases of central nervous system	0.001	0.200	0.799
J86 Pyothorax	0.797	0.203	0.000
M08 Juvenile arthritis	0.797	0.203	0.000
H91.8 Other specified hearing loss	0.796	0.204	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.000	0.205	0.795
M06.8 Other specified rheumatoid arthritis	0.794	0.206	0.000
H36.0 Diabetic retinopathy	0.794	0.206	0.000
J32.1 Chronic frontal sinusitis	0.791	0.209	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.000	0.209	0.791
C82.2 Large cell, follicular	0.791	0.209	0.000
J00-J06 Acute upper respiratory infections	0.789	0.211	0.000
E14.0 With coma	0.789	0.211	0.000
D69.0 Allergic purpura	0.000	0.213	0.787
D69.6 Thrombocytopenia, unspecified	0.000	0.216	0.784
J35.2 Hypertrophy of adenoids	0.783	0.217	0.000
M14.6 Neuropathic arthropathy	0.783	0.217	0.000
K90 Intestinal malabsorption	0.000	0.219	0.781
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.220	0.780
E11.8 With unspecified complications	0.780	0.220	0.000
J32.2 Chronic ethmoidal sinusitis	0.779	0.221	0.000
E14.1 With ketoacidosis	0.777	0.223	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.777	0.223	0.000
M91-M94 Chondropathies	0.776	0.224	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.775	0.225	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.773	0.227	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.772	0.228	0.000
L04 Acute lymphadenitis	0.772	0.228	0.000
E70-E90 Metabolic disorders	0.771	0.229	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.768	0.232	0.000
E10.7 With multiple complications	0.768	0.232	0.000
M12 Other specific arthropathies	0.768	0.232	0.000
L40.4 Guttate psoriasis	0.765	0.235	0.000
J06 Acute upper respiratory infections of multiple and unspecified sites	0.761	0.239	0.000
E11.3 With ophthalmic complications	0.761	0.239	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.000	0.240	0.760
D59 Acquired haemolytic anaemia	0.000	0.241	0.759
M46.1 Sacro-iliitis, not elsewhere classified	0.759	0.241	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.757	0.243	0.000
C82.1 Mixed small cleaved and large cell, follicular	0.756	0.244	0.000
J33.1 Polypoid sinus degeneration	0.753	0.247	0.000
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites	0.753	0.247	0.000
E14.8 With unspecified complications	0.751	0.248	0.000
M60-M63 Disorders of muscles	0.750	0.250	0.000
L43.0 Hypertrophic lichen planus	0.750	0.250	0.000
D86.8 Sarcoidosis of other and combined sites	0.000	0.251	0.749
M65.4 Radial styloid tenosynovitis [de Quervain]	0.748	0.252	0.000
L40.1 Generalised pustular psoriasis	0.748	0.252	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.747	0.253	0.000
D69.4 Other primary thrombocytopenia	0.000	0.253	0.747
M07.38 Other psoriatic arthropathies (Other)	0.747	0.253	0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.747	0.253	0.000
M66 Spontaneous rupture of synovium and tendon	0.745	0.255	0.000
J06.9 Acute upper respiratory infection, unspecified	0.743	0.257	0.000
D68.0 Von Willebrand's disease	0.000	0.260	0.740
J95-J99 Other diseases of the respiratory system	0.740	0.260	0.000
M65.1 Other infective (teno)synovitis	0.739	0.261	0.000
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)	0.738	0.262	0.000
E14.2 Withrenal complications	0.737	0.263	0.000
E16.1 Other hypoglycaemia	0.737	0.263	0.000
M65.8 Other synovitis and tenosynovitis	0.737	0.263	0.000
E14.5 With peripheral circulatory complications	0.736	0.264	0.000
M25.47 Effusion of joint (Ankle and foot)	0.735	0.265	0.000
J45.1 Nonallergic asthma	0.732	0.268	0.000
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)	0.732	0.268	0.000
C82.4 Follicular lymphoma grade IIIb	0.729	0.271	0.000
E14.9 Without complications	0.728	0.272	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.728	0.272	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.726	0.274	0.000
D66 Hereditary factor VIII deficiency	0.000	0.277	0.723
H36 Retinal disorders in diseases classified elsewhere	0.721	0.279	0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.721	0.279	0.000
J43.2 Centrilobular emphysema	0.721	0.279	0.000
L44 Other papulosquamous disorders	0.720	0.280	0.000
E11.6 With other specified complications	0.720	0.280	0.000
D68.4 Acquired coagulation factor deficiency	0.000	0.280	0.720
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.719	0.281	0.000
M94 Other disorders of cartilage	0.717	0.283	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.717	0.283	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.000	0.283	0.717
E11.7 With multiple complications	0.717	0.283	0.000
L40.2 Acrodermatitis continua	0.717	0.283	0.000
M06.2 Rheumatoid bursitis	0.717	0.283	0.000
M06.1 Adult-onset Still's disease	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.717	0.283	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.717	0.283	0.000
M05.0 Felty's syndrome	0.717	0.283	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.717	0.283	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.717	0.283	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.717	0.283	0.000
L41 Parapsoriasis	0.717	0.283	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.717	0.283	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.717	0.283	0.000
M06.38 Rheumatoid nodule (Other)	0.717	0.283	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.717	0.283	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.717	0.283	0.000
D81 Combined immunodeficiencies	0.000	0.283	0.717
L40.0 Psoriasis vulgaris	0.716	0.284	0.000
M07.5 Arthropathy in ulcerative colitis	0.716	0.284	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.716	0.284	0.000
M07.2 Psoriatic spondylitis	0.716	0.284	0.000
M07.1 Arthritis mutilans	0.716	0.284	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.716	0.284	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.715	0.285	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.715	0.285	0.000
E03.5 Myxoedema coma	0.714	0.285	0.000
E03.4 Atrophy of thyroid (acquired)	0.714	0.285	0.000
E03.3 Postinfectious hypothyroidism	0.714	0.285	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.714	0.285	0.001
E00 Congenital iodine-deficiency syndrome	0.714	0.285	0.001
M35.9 Systemic involvement of connective tissue, unspecified	0.712	0.288	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.712	0.288	0.000
M35.5 Multifocal fibrosclerosis	0.712	0.288	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.712	0.288	0.000
L43.3 Subacute (active) lichen planus	0.712	0.288	0.000
L43.2 Lichenoid drug reaction	0.712	0.288	0.000
L43.1 Bullous lichen planus	0.712	0.288	0.000
E14.4 With neurological complications	0.711	0.289	0.000
J45.8 Mixed asthma	0.710	0.290	0.000
M00.9 Pyogenic arthritis, unspecified	0.710	0.290	0.000
C82.6 Cutaneous follicle centre lymphoma	0.709	0.291	0.000
C82.5 Diffuse follicle centre lymphoma	0.709	0.291	0.000
D59.1 Other autoimmune haemolytic anaemias	0.000	0.293	0.707
Chapter XVI Certain conditions originating in the perinatal period	0.706	0.293	0.000
M11 Other crystal arthropathies	0.706	0.294	0.000
D89.3 Immune reconstitution syndrome	0.000	0.295	0.705
H91.0 Ototoxic hearing loss	0.705	0.295	0.000
E15 Nondiabetic hypoglycaemic coma	0.705	0.295	0.000
M25.40 Effusion of joint (Multiple sites)	0.705	0.295	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.296	0.704
G37.9 Demyelinating disease of central nervous system, unspecified	0.000	0.296	0.704
E14.7 With multiple complications	0.703	0.297	0.000
L00 Staphylococcal scalded skin syndrome	0.703	0.297	0.000
J85 Abscess of lung and mediastinum	0.703	0.297	0.000
M05.2 Rheumatoid vasculitis	0.702	0.297	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.702	0.298	0.000
M31.2 Lethal midline granuloma	0.701	0.299	0.000
M46.18 Sacroiliitis, not elsewhere classified-Sacral/sacrococ	0.701	0.299	0.000
L42 Pityriasis rosea	0.700	0.300	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.699	0.301	0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.699	0.301	0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.699	0.301	0.000
M45.X4 Ankylosing spondylitis (Thoracic region)	0.699	0.301	0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.699	0.301	0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.699	0.301	0.000
E05.5 Thyroid crisis or storm	0.023	0.302	0.675
E05.4 Thyrotoxicosis factitia	0.023	0.302	0.675
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.023	0.302	0.675
H94 Other disorders of ear in diseases classified elsewhere	0.697	0.302	0.000
M05.19 Rheumatoid lung disease (Site unspecified)	0.697	0.302	0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.000	0.303	0.697
M31.8 Other specified necrotising vasculopathies	0.697	0.303	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.696	0.303	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.696	0.303	0.000
E16.4 Abnormal secretion of gastrin	0.696	0.303	0.000
E16.3 Increased secretion of glucagon	0.696	0.303	0.000
M65.0 Abscess of tendon sheath	0.696	0.304	0.000
M02 Reactive arthropathies	0.696	0.304	0.000
M65.2 Calcific tendinitis	0.695	0.305	0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.695	0.305	0.000
M07.6 Other enteropathic arthropathies	0.694	0.306	0.000
M65.98 Synovitis and tenosynovitis, unspecified (Other)	0.693	0.307	0.000
M31.3 Wegener's granulomatosis	0.692	0.308	0.000
M25.8 Other specified joint disorders	0.691	0.309	0.000
D84 Other immunodeficiencies	0.000	0.312	0.688
D89.1 Cryoglobulinaemia	0.000	0.312	0.687
J32.0 Chronic maxillary sinusitis	0.688	0.312	0.000
J86.0 Pyothorax with fistula	0.687	0.313	0.000
M31.1 Thrombotic microangiopathy	0.683	0.316	0.000
M94.8 Other specified disorders of cartilage	0.683	0.317	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.681	0.318	0.000
G37.8 Other specified demyelinating diseases of central nervous system	0.001	0.319	0.681
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.000	0.319	0.681
M34.8 Other forms of systemic sclerosis	0.681	0.319	0.000
H91.2 Sudden idiopathic hearing loss	0.677	0.323	0.000
M30.8 Other conditions related to polyarteritis nodosa	0.677	0.323	0.000
M31.9 Necrotising vasculopathy, unspecified	0.677	0.323	0.000
J43.8 Other emphysema	0.676	0.324	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.675	0.325	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.674	0.326	0.000
L40.3 Pustulosis palmaris et plantaris	0.674	0.326	0.000
L10-L14 Bullous disorders	0.673	0.327	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.672	0.328	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.672	0.328	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.672	0.328	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.672	0.328	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.672	0.328	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.672	0.328	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.672	0.328	0.000
E78.5 Hyperlipidaemia, unspecified	0.672	0.328	0.000
J43.1 Panlobular emphysema	0.672	0.328	0.000
J43.0 MacLeod's syndrome	0.672	0.328	0.000
Chapter VII Diseases of the eye and adnexa	0.670	0.330	0.000
J99 Respiratory disorders in diseases classified elsewhere	0.670	0.330	0.000
H30-H36 Disorders of choroid and retina	0.669	0.331	0.000
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified	0.668	0.332	0.000
L01 Impetigo	0.664	0.336	0.000
J35.3 Hypertrophy of tonsils with hypertrophy of adenoids	0.663	0.337	0.000
D67 Hereditary factor IX deficiency	0.000	0.338	0.662
J41 Simple and mucopurulent chronic bronchitis	0.662	0.338	0.000
M60 Myositis	0.660	0.340	0.000
D69.9 Haemorrhagic condition, unspecified	0.000	0.341	0.659
H92 Otalgia and effusion of ear	0.659	0.341	0.000
E05.8 Other thyrotoxicosis	0.022	0.341	0.636
M35.1 Other overlap syndromes	0.658	0.342	0.000
M08.0 Juvenile rheumatoid arthritis	0.657	0.343	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.656	0.344	0.000
M25.9 Joint disorder, unspecified	0.655	0.345	0.000
M34.1 CR(E)ST syndrome	0.654	0.346	0.000
J86.9 Pyothorax without fistula	0.653	0.347	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.000	0.349	0.651
E03.8 Other specified hypothyroidism	0.651	0.349	0.000
M00.8 Arthritis and polyarthritis due to other specified bacterial agents	0.650	0.349	0.000
M30.0 Polyarteritis nodosa	0.650	0.350	0.000
M66.3 Spontaneous rupture of flexor tendons	0.648	0.352	0.000
D57 Sickle-cell disorders	0.000	0.353	0.647
J05 Acute obstructive laryngitis [croup] and epiglottitis	0.646	0.354	0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.645	0.355	0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.645	0.355	0.000
E03.1 Congenital hypothyroidism without goitre	0.644	0.355	0.000
D52.8 Other folate deficiency anaemias	0.000	0.358	0.642
D52.1 Drug-induced folate deficiency anaemia	0.000	0.358	0.642
D52.0 Dietary folate deficiency anaemia	0.000	0.358	0.642
E13.3 With ophthalmic complications	0.642	0.358	0.000
E40-E46 Malnutrition	0.641	0.359	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.000	0.359	0.641
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.640	0.360	0.000
M49 Spondylopathies in diseases classified elsewhere	0.637	0.362	0.000
M35.2 Behcet's disease	0.635	0.364	0.000
J32.3 Chronic sphenoidal sinusitis	0.635	0.364	0.000
K90.9 Intestinal malabsorption, unspecified	0.000	0.365	0.635
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.635	0.365	0.000
D68.6 Other Thrombophilia	0.000	0.367	0.633
M14.2 Diabetic arthropathy	0.633	0.367	0.000
L40.8 Other psoriasis	0.633	0.367	0.000
M65.86 Other synovitis and tenosynovitis (Lower leg)	0.631	0.369	0.000
J99.0 Rheumatoid lung disease	0.629	0.371	0.000
L04.0 Acute lymphadenitis of face, head and neck	0.628	0.372	0.000
D82 Immunodeficiency associated with other major defects	0.000	0.372	0.628
J37 Chronic laryngitis and laryngotracheitis	0.627	0.373	0.000
E06 Thyroiditis	0.625	0.374	0.001
E13.9 Without complications	0.626	0.374	0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.625	0.375	0.000
M30.2 Juvenile polyarteritis	0.625	0.375	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.625	0.375	0.000
M20 Acquired deformities of fingers and toes	0.624	0.376	0.000
D51.2 Transcobalamin II deficiency	0.000	0.378	0.622
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.000	0.378	0.622
M34.0 Progressive systemic sclerosis	0.622	0.378	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.621	0.378	0.001
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.025	0.380	0.595
M05.88 Other seropositive rheumatoid arthritis (Other)	0.619	0.381	0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.619	0.381	0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.619	0.381	0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.619	0.381	0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.619	0.381	0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.619	0.381	0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.619	0.381	0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.619	0.381	0.000
H40-H42 Glaucoma	0.619	0.381	0.000
D69.8 Other specified haemorrhagic conditions	0.000	0.382	0.618
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)	0.617	0.383	0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.616	0.384	0.000
M14.4 Arthropathy in amyloidosis	0.616	0.384	0.000
M14.3 Lipoid dermatoarthritis	0.616	0.384	0.000
M14.1 Crystal arthropathy in other metabolic disorders	0.616	0.384	0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.616	0.384	0.000
M25.2 Flail joint	0.615	0.385	0.000
M25.1 Fistula of joint	0.615	0.385	0.000
M25.0 Haemarthrosis	0.614	0.386	0.000
M66.5 Spontaneous rupture of unspecified tendon	0.614	0.386	0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.613	0.387	0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.611	0.389	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.611	0.389	0.000
M46.4 Discitis, unspecified	0.611	0.389	0.000
M00.92 Pyogenic arthritis, unspecified (Upper arm)	0.610	0.390	0.000
M46.2 Osteomyelitis of vertebra	0.609	0.391	0.000
L03 Cellulitis	0.607	0.393	0.000
D55 Anaemia due to enzyme disorders	0.000	0.394	0.606
M65.81 Other synovitis and tenosynovitis (Shoulder region)	0.603	0.397	0.000
M60.0 Infective myositis	0.602	0.398	0.000
D56 Thalassaemia	0.000	0.398	0.602
M25.49 Effusion of joint (Site unspecified)	0.601	0.398	0.000
M25.48 Effusion of joint (Other)	0.601	0.398	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.600	0.400	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.598	0.402	0.000
M25.5 Pain in joint	0.596	0.404	0.000
M00.0 Staphylococcal arthritis and polyarthritis	0.596	0.404	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.596	0.404	0.000
M46.8 Other specified inflammatory spondylopathies	0.595	0.405	0.000
M46.5 Other infective spondylopathies	0.595	0.405	0.000
D69.1 Qualitative platelet defects	0.000	0.406	0.594
E84 Cystic fibrosis	0.594	0.406	0.000
M31.0 Hypersensitivity angiitis	0.593	0.407	0.000
M35.8 Other specified systemic involvement of connective tissue	0.591	0.409	0.000
M05.18 Rheumatoid lung disease (Other)	0.591	0.409	0.000
M05.17 Rheumatoid lung disease (Ankle and foot)	0.591	0.409	0.000
M05.16 Rheumatoid lung disease (Lower leg)	0.591	0.409	0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.591	0.409	0.000
M05.14 Rheumatoid lung disease (Hand)	0.591	0.409	0.000
M05.13 Rheumatoid lung disease (Forearm)	0.591	0.409	0.000
M05.12 Rheumatoid lung disease (Upper arm)	0.591	0.409	0.000
M05.11 Rheumatoid lung disease (Shoulder region)	0.591	0.409	0.000
M05.10 Rheumatoid lung disease (Multiple sites)	0.591	0.409	0.000
E78.6 Lipoprotein deficiency	0.591	0.409	0.000
E72 Other disorders of amino-acid metabolism	0.590	0.409	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.588	0.412	0.000
M02.3 Reiter's disease	0.586	0.414	0.000
D83 Common variable immunodeficiency	0.000	0.416	0.584
M46.0 Spinal enthesopathy	0.584	0.416	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.584	0.416	0.000
H40 Glaucoma	0.583	0.417	0.000
E13.8 With unspecified complications	0.581	0.419	0.000
E13.7 With multiple complications	0.581	0.419	0.000
E13.6 With other specified complications	0.581	0.419	0.000
E13.5 With peripheral circulatory complications	0.581	0.419	0.000
E13.4 With neurological complications	0.581	0.419	0.000
E13.2 With renal complications	0.581	0.419	0.000
E13.1 With ketoacidosis	0.581	0.419	0.000
E13.0 With coma	0.581	0.419	0.000
M00.2 Other streptococcal arthritis and polyarthritis	0.580	0.420	0.000
M00.1 Pneumococcal arthritis and polyarthritis	0.580	0.420	0.000
L04.8 Acute lymphadenitis of other sites	0.580	0.420	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations