TreeWAS – Variant ID: rs12197554

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Z85.5 Personal history of malignant neoplasm of urinary tract	0.197	0.803	0.000
C67.9 Bladder, unspecified	0.151	0.849	0.000
C67 Malignant neoplasm of bladder	0.095	0.905	0.000
C67.1 Dome of bladder	0.082	0.918	0.000
C67.6 Ureteric orifice	0.078	0.922	0.000
M25.46 Effusion of joint (Lower leg)	0.075	0.925	0.000
C67.2 Lateral wall of bladder	0.073	0.927	0.000
C67.0 Trigone of bladder	0.069	0.931	0.000
C67.5 Bladder neck	0.068	0.932	0.000
C67.7 Urachus	0.068	0.932	0.000
C67.8 Overlapping lesion of bladder	0.068	0.932	0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm	0.068	0.932	0.000
C67.4 Posterior wall of bladder	0.065	0.935	0.000
Z08 Follow-up examination after treatment for malignant neoplasm	0.061	0.939	0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm	0.056	0.944	0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm	0.056	0.944	0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm	0.050	0.950	0.000
C67.3 Anterior wall of bladder	0.048	0.952	0.000
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm	0.047	0.953	0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm	0.040	0.960	0.000
M25.4 Effusion of joint	0.038	0.962	0.000
M25.43 Effusion of joint (Forearm)	0.031	0.969	0.000
M25.40 Effusion of joint (Multiple sites)	0.031	0.969	0.000
M25.42 Effusion of joint (Upper arm)	0.030	0.970	0.000
M25.49 Effusion of joint (Site unspecified)	0.027	0.973	0.000
M25.48 Effusion of joint (Other)	0.027	0.973	0.000
M25.44 Effusion of joint (Hand)	0.027	0.973	0.000
M25.41 Effusion of joint (Shoulder region)	0.027	0.973	0.000
M25.45 Effusion of joint (Pelvic region and thigh)	0.025	0.975	0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified	0.025	0.975	0.000
O20.0 Threatened abortion	0.000	0.975	0.025
O20 Haemorrhage in early pregnancy	0.000	0.976	0.024
O20.9 Haemorrhage in early pregnancy, unspecified	0.000	0.978	0.022
O20.8 Other haemorrhage in early pregnancy	0.000	0.979	0.021
M25.47 Effusion of joint (Ankle and foot)	0.021	0.979	0.000
S72.00 Fracture of neck of femur (closed)	0.018	0.982	0.000
S72.0 Fracture of neck of femur	0.017	0.983	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.000	0.983	0.017
S72 Fracture of femur	0.016	0.984	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.984	0.016
S72.1 Pertrochanteric fracture	0.015	0.985	0.000
S72.10 Pertrochanteric fracture (closed)	0.015	0.985	0.000
O24 Diabetes mellitus in pregnancy	0.000	0.986	0.014
O28 Abnormal findings on antenatal screening of mother	0.000	0.986	0.014
S72.4 Fracture of lower end of femur	0.014	0.986	0.000
O21 Excessive vomiting in pregnancy	0.000	0.987	0.013
O23 Infections of genito-urinary tract in pregnancy	0.000	0.987	0.013
S72.2 Subtrochanteric fracture	0.013	0.987	0.000
E87.5 Hyperkalaemia	0.000	0.987	0.013
E87 Other disorders of fluid, electrolyte and acid-base balance	0.000	0.988	0.012
E87.7 Fluid overload	0.000	0.988	0.012
S70-S79 Injuries to the hip and thigh	0.012	0.988	0.000
S72.01 Fracture of neck of femur (open)	0.012	0.988	0.000
S72.9 Fracture of femur, part unspecified	0.012	0.988	0.000
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.000	0.988	0.012
O22 Venous complications in pregnancy	0.000	0.988	0.012
O29 Complications of anaesthesia during pregnancy	0.000	0.988	0.012
O25 Malnutrition in pregnancy	0.000	0.988	0.012
I21.9 Acute myocardial infarction, unspecified	0.000	0.988	0.012
S72.8 Fractures of other parts of femur	0.012	0.988	0.000
S72.7 Multiple fractures of femur	0.012	0.988	0.000
S72.3 Fracture of shaft of femur	0.012	0.988	0.000
S72.40 Fracture of lower end of femur (closed)	0.012	0.988	0.000
C64-C68 Malignant neoplasms of urinary tract	0.012	0.988	0.000
O24.4 Diabetes mellitus arising in pregnancy	0.000	0.988	0.012
K25.3 Acute without haemorrhage or perforation	0.012	0.988	0.000
E87.2 Acidosis	0.000	0.988	0.012
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.000	0.988	0.012
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.000	0.988	0.011
S79 Other and unspecified injuries of hip and thigh	0.011	0.989	0.000
S72.11 Pertrochanteric fracture (open)	0.011	0.989	0.000
O21.9 Vomiting of pregnancy, unspecified	0.000	0.989	0.011
T81 Complications of procedures, not elsewhere classified	0.011	0.989	0.000
I21 Acute myocardial infarction	0.000	0.989	0.011
S79.9 Unspecified injury of hip and thigh	0.011	0.989	0.000
O23.4 Unspecified infection of urinary tract in pregnancy	0.000	0.989	0.011
O24.9 Diabetes mellitus in pregnancy, unspecified	0.000	0.990	0.010
O24.3 Pre-existing diabetes mellitus, unspecified	0.000	0.990	0.010
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.000	0.990	0.010
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.000	0.990	0.010
E87.3 Alkalosis	0.000	0.990	0.010
O28.9 Abnormal finding on antenatal screening of mother, unspecified	0.000	0.990	0.010
O28.8 Other abnormal findings on antenatal screening of mother	0.000	0.990	0.010
O28.5 Abnormal chromosomal and genetic finding on antenatal screening of mother	0.000	0.990	0.010
O28.4 Abnormal radiological finding on antenatal screening of mother	0.000	0.990	0.010
O28.3 Abnormal ultrasonic finding on antenatal screening of mother	0.000	0.990	0.010
O28.2 Abnormal cytological finding on antenatal screening of mother	0.000	0.990	0.010
O28.0 Abnormal haematological finding on antenatal screening of mother	0.000	0.990	0.010
O21.0 Mild hyperemesis gravidarum	0.000	0.990	0.010
T81.9 Unspecified complication of procedure	0.010	0.990	0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.010	0.990	0.000
O23.9 Other and unspecified genito-urinary tract infection in pregnancy	0.000	0.990	0.010
S72.41 Fracture of lower end of femur (open)	0.010	0.990	0.000
O21.8 Other vomiting complicating pregnancy	0.000	0.990	0.010
O21.2 Late vomiting of pregnancy	0.000	0.990	0.010
O23.3 Infections of other parts of urinary tract in pregnancy	0.000	0.990	0.010
O23.2 Infections of urethra in pregnancy	0.000	0.990	0.010
O23.1 Infections of bladder in pregnancy	0.000	0.990	0.010
O23.0 Infections of kidney in pregnancy	0.000	0.990	0.010
S72.20 Subtrochanteric fracture (closed)	0.010	0.990	0.000
O23.5 Infections of the genital tract in pregnancy	0.000	0.990	0.010
S71 Open wound of hip and thigh	0.010	0.990	0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified	0.010	0.990	0.000
T81.3 Disruption of operation wound, not elsewhere classified	0.010	0.990	0.000
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.000	0.991	0.009
S72.90 Fracture of femur, part unspecified (closed)	0.009	0.991	0.000
S72.21 Subtrochanteric fracture (open)	0.009	0.991	0.000
E87.4 Mixed disorder of acid-base balance	0.000	0.991	0.009
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.991	0.009
O22.4 Haemorrhoids in pregnancy	0.000	0.991	0.009
S78 Traumatic amputation of hip and thigh	0.009	0.991	0.000
S77 Crushing injury of hip and thigh	0.009	0.991	0.000
S76 Injury of muscle and tendon at hip and thigh level	0.009	0.991	0.000
S75 Injury of blood vessels at hip and thigh level	0.009	0.991	0.000
S74 Injury of nerves at hip and thigh level	0.009	0.991	0.000
S72.91 Fracture of femur, part unspecified (open)	0.009	0.991	0.000
O22.9 Venous complication in pregnancy, unspecified	0.000	0.991	0.009
O22.8 Other venous complications in pregnancy	0.000	0.991	0.009
O22.5 Cerebral venous thrombosis in pregnancy	0.000	0.991	0.009
O22.3 Deep phlebothrombosis in pregnancy	0.000	0.991	0.009
O22.2 Superficial thrombophlebitis in pregnancy	0.000	0.991	0.009
O22.1 Genital varices in pregnancy	0.000	0.991	0.009
O22.0 Varicose veins of lower extremity in pregnancy	0.000	0.991	0.009
O29.9 Complication of anaesthesia during pregnancy, unspecified	0.000	0.991	0.009
O29.8 Other complications of anaesthesia during pregnancy	0.000	0.991	0.009
O29.6 Failed or difficult intubation during pregnancy	0.000	0.991	0.009
O29.5 Other complications of spinal and epidural anaesthesia during pregnancy	0.000	0.991	0.009
O29.4 Spinal and epidural anaesthesia-induced headache during pregnancy	0.000	0.991	0.009
O29.3 Toxic reaction to local anaesthesia during pregnancy	0.000	0.991	0.009
O29.2 Central nervous system complications of anaesthesia during pregnancy	0.000	0.991	0.009
O29.1 Cardiac complications of anaesthesia during pregnancy	0.000	0.991	0.009
O29.0 Pulmonary complications of anaesthesia during pregnancy	0.000	0.991	0.009
S72.31 Fracture of shaft of femur (open)	0.009	0.991	0.000
S72.71 Multiple fractures of femur (open)	0.009	0.991	0.000
S72.70 Multiple fractures of femur (closed)	0.009	0.991	0.000
S72.81 Fractures of other parts of femur (open)	0.009	0.991	0.000
S72.80 Fractures of other parts of femur (closed)	0.009	0.991	0.000
S72.30 Fracture of shaft of femur (closed)	0.009	0.991	0.000
C68 Malignant neoplasm of other and unspecified urinary organs	0.009	0.991	0.000
S70 Superficial injury of hip and thigh	0.009	0.991	0.000
S73.1 Sprain and strain of hip	0.008	0.991	0.000
S79.8 Other specified injuries of hip and thigh	0.008	0.992	0.000
S79.7 Multiple injuries of hip and thigh	0.008	0.992	0.000
E87.6 Hypokalaemia	0.000	0.992	0.008
T81.8 Other complications of procedures, not elsewhere classified	0.008	0.992	0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure	0.008	0.992	0.000
T81.7 Vascular complications following a procedure, not elsewhere classified	0.008	0.992	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.992	0.008
E87.0 Hyperosmolality and hypernatraemia	0.000	0.992	0.008
S73.0 Dislocation of hip	0.008	0.992	0.000
O26 Maternal care for other conditions predominantly related to pregnancy	0.000	0.992	0.008
C43.5 Malignant melanoma of trunk	0.000	0.992	0.008
C66 Malignant neoplasm of ureter	0.008	0.992	0.000
S71.1 Open wound of thigh	0.008	0.992	0.000
C65 Malignant neoplasm of renal pelvis	0.007	0.993	0.000
S71.8 Open wound of other and unspecified parts of pelvic girdle	0.007	0.993	0.000
S71.7 Multiple open wounds of of hip and thigh	0.007	0.993	0.000
S71.0 Open wound of hip	0.007	0.993	0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure	0.007	0.993	0.000
I25.1 Atherosclerotic heart disease	0.000	0.993	0.007
C43.6 Malignant melanoma of upper limb, including shoulder	0.000	0.993	0.007
E14.9 Without complications	0.000	0.993	0.007
S74.9 Injury of unspecified nerve at hip and thigh level	0.007	0.993	0.000
S74.8 Injury of other nerves at hip and thigh level	0.007	0.993	0.000
S74.7 Injury of multiple nerves at hip and thigh level	0.007	0.993	0.000
S74.2 Injury of cutaneous sensory nerve at hip and thigh level	0.007	0.993	0.000
S74.1 Injury of femoral nerve at hip and thigh level	0.007	0.993	0.000
S74.0 Injury of sciatic nerve at hip and thigh level	0.007	0.993	0.000
S75.9 Injury of unspecified blood vessel at hip and thigh level	0.007	0.993	0.000
S75.8 Injury of other blood vessels at hip and thigh level	0.007	0.993	0.000
S75.7 Injury of multiple blood vessels at hip and thigh level	0.007	0.993	0.000
S75.2 Injury of greater saphenous vein at hip and thigh level	0.007	0.993	0.000
S75.1 Injury of femoral vein at hip and thigh level	0.007	0.993	0.000
S75.0 Injury of femoral artery	0.007	0.993	0.000
S76.1 Injury of quadriceps muscle and tendon	0.007	0.993	0.000
S76.7 Injury of multiple muscles and tendons at hip and thigh level	0.007	0.993	0.000
S76.4 Injury of other and unspecified muscles and tendons at thigh level	0.007	0.993	0.000
S76.3 Injury of muscle and tendon of the posterior muscle group at thigh level	0.007	0.993	0.000
S76.2 Injury of adductor muscle and tendon of thigh	0.007	0.993	0.000
S76.0 Injury of muscle and tendon of hip	0.007	0.993	0.000
S77.2 Crushing injury of hip with thigh	0.007	0.993	0.000
S77.1 Crushing injury of thigh	0.007	0.993	0.000
S77.0 Crushing injury of hip	0.007	0.993	0.000
S78.9 Traumatic amputation of hip and thigh, level unspecified	0.007	0.993	0.000
S78.1 Traumatic amputation at level between hip and knee	0.007	0.993	0.000
S78.0 Traumatic amputation at hip joint	0.007	0.993	0.000
S70.1 Contusion of thigh	0.007	0.993	0.000
C68.9 Urinary organ, unspecified	0.006	0.993	0.000
C68.8 Overlapping lesion of urinary organs	0.006	0.993	0.000
C68.1 Paraurethral glands	0.006	0.993	0.000
C68.0 Urethra	0.006	0.993	0.000
S70.8 Other superficial injuries of hip and thigh	0.006	0.993	0.000
S70.7 Multiple superficial injuries of hip and thigh	0.006	0.993	0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.000	0.993	0.006
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.994	0.006
S70.9 Superficial injury of hip and thigh, unspecified	0.006	0.994	0.000
C43 Malignant melanoma of skin	0.000	0.994	0.006
I25.2 Old myocardial infarction	0.000	0.994	0.006
S70.0 Contusion of hip	0.006	0.994	0.000
O26.5 Maternal hypotension syndrome	0.000	0.994	0.006
O26.4 Herpes gestationis	0.000	0.994	0.006
O26.3 Retained intra-uterine contraceptive device in pregnancy	0.000	0.994	0.006
O26.1 Low weight gain in pregnancy	0.000	0.994	0.006
O26.0 Excessive weight gain in pregnancy	0.000	0.994	0.006
I25 Chronic ischaemic heart disease	0.000	0.994	0.006
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.994	0.006
C43.7 Malignant melanoma of lower limb, including hip	0.000	0.994	0.006
O26.2 Pregnancy care of habitual aborter	0.000	0.994	0.006
O26.6 Liver disorders in pregnancy, childbirth and the puerperium	0.000	0.994	0.005
S76.10 Unspecified injury of quadriceps muscle, fascia and tendon	0.005	0.995	0.000
I25.5 Ischaemic cardiomyopathy	0.000	0.995	0.005
I25.0 Atherosclerotic cardiovascular disease, so described	0.000	0.995	0.005
E87.1 Hypo-osmolality and hyponatraemia	0.000	0.995	0.005
I20-I25 Ischaemic heart diseases	0.000	0.995	0.005
O26.8 Other specified pregnancy-related conditions	0.000	0.995	0.005
K25 Gastric ulcer	0.005	0.995	0.000
C43.4 Malignant melanoma of scalp and neck	0.000	0.995	0.005
K25.4 Chronic or unspecified with haemorrhage	0.005	0.995	0.000
T81.4 Infection following a procedure, not elsewhere classified	0.005	0.995	0.000
C43.8 Overlapping malignant melanoma of skin	0.000	0.995	0.005
C43.1 Malignant melanoma of eyelid, including canthus	0.000	0.995	0.005
C43.0 Malignant melanoma of lip	0.000	0.995	0.005
N86 Erosion and ectropion of cervix uteri	0.000	0.995	0.005
C43.9 Malignant melanoma of skin, unspecified	0.000	0.995	0.005
K25.6 Chronic or unspecified with both haemorrhage and perforation	0.004	0.995	0.000
I25.6 Silent myocardial ischaemia	0.000	0.995	0.004
R06.8 Other and unspecified abnormalities of breathing	0.000	0.995	0.005
I22 Subsequent myocardial infarction	0.000	0.996	0.004
T83.3 Mechanical complication of intra-uterine contraceptive device	0.000	0.996	0.004
C43.2 Malignant melanoma of ear and external auricular canal	0.000	0.996	0.004
M89.8 Other specified disorders of bone	0.004	0.996	0.000
I25.4 Coronary artery aneurysm	0.000	0.996	0.004
M89.87 Other specified disorders of bone (Ankle and foot)	0.004	0.996	0.000
J32.9 Chronic sinusitis, unspecified	0.004	0.996	0.000
K25.0 Acute with haemorrhage	0.004	0.996	0.000
I23 Certain current complications following acute myocardial infarction	0.000	0.996	0.004
R72 Abnormality of white blood cells, not elsewhere classified	0.004	0.996	0.000
M89 Other disorders of bone	0.004	0.996	0.000
K25.5 Chronic or unspecified with perforation	0.004	0.996	0.000
K25.2 Acute with both haemorrhage and perforation	0.004	0.996	0.000
K25.1 Acute with perforation	0.004	0.996	0.000
M89.88 Other specified disorders of bone (Other)	0.004	0.996	0.000
I25.3 Aneurysm of heart	0.000	0.996	0.004
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.996	0.004
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.996	0.004
M89.0 Algoneurodystrophy	0.004	0.996	0.000
M89.9 Disorder of bone, unspecified	0.004	0.996	0.000
N64.5 Other signs and symptoms in breast	0.004	0.996	0.000
O26.9 Pregnancy-related condition, unspecified	0.000	0.996	0.004
M89.84 Other specified disorders of bone (Hand)	0.004	0.996	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.996	0.004
M89.04 Algoneurodystrophy (Hand)	0.003	0.996	0.000
M89.81 Other specified disorders of bone (Shoulder region)	0.003	0.996	0.000
I31.9 Disease of pericardium, unspecified	0.004	0.996	0.000
M89.92 Disorder of bone, unspecified (Upper arm)	0.003	0.997	0.000
M89.89 Other specified disorders of bone (Site unspecified)	0.003	0.997	0.000
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.003	0.997	0.000
M89.83 Other specified disorders of bone (Forearm)	0.003	0.997	0.000
M89.82 Other specified disorders of bone (Upper arm)	0.003	0.997	0.000
M89.80 Other specified disorders of bone (Multiple sites)	0.003	0.997	0.000
M89.96 Disorder of bone, unspecified (Lower leg)	0.003	0.997	0.000
M89.86 Other specified disorders of bone (Lower leg)	0.003	0.997	0.000
M89.94 Disorder of bone, unspecified (Hand)	0.003	0.997	0.000
I23.8 Other current complications following acute myocardial infarction	0.000	0.997	0.003
M89.3 Hypertrophy of bone	0.003	0.997	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.000	0.997	0.003
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.000	0.997	0.003
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.000	0.997	0.003
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.000	0.997	0.003
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.000	0.997	0.003
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.000	0.997	0.003
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.000	0.997	0.003
K25.7 Chronic without haemorrhage or perforation	0.003	0.997	0.000
Z39.0 Care and examination immediately after delivery	0.003	0.997	0.000
N64 Other disorders of breast	0.003	0.997	0.000
M89.6 Osteopathy after poliomyelitis	0.003	0.997	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.003	0.997	0.000
M89.2 Other disorders of bone development and growth	0.003	0.997	0.000
M89.1 Epiphyseal arrest	0.003	0.997	0.000
M89.5 Osteolysis	0.003	0.997	0.000
M89.07 Algoneurodystrophy (Ankle and foot)	0.003	0.997	0.000
I22.8 Subsequent myocardial infarction of other sites	0.000	0.997	0.003
N64.8 Other specified disorders of breast	0.003	0.997	0.000
N64.1 Fat necrosis of breast	0.003	0.997	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.997	0.003
M89.09 Algoneurodystrophy (Site unspecified)	0.003	0.997	0.000
M89.08 Algoneurodystrophy (Other)	0.003	0.997	0.000
M89.06 Algoneurodystrophy (Lower leg)	0.003	0.997	0.000
M89.05 Algoneurodystrophy (Pelvic region and thigh)	0.003	0.997	0.000
M89.02 Algoneurodystrophy (Upper arm)	0.003	0.997	0.000
M89.01 Algoneurodystrophy (Shoulder region)	0.003	0.997	0.000
M89.00 Algoneurodystrophy (Multiple sites)	0.003	0.997	0.000
M89.99 Disorder of bone, unspecified (Site unspecified)	0.003	0.997	0.000
M89.98 Disorder of bone, unspecified (Other)	0.003	0.997	0.000
M89.93 Disorder of bone, unspecified (Forearm)	0.003	0.997	0.000
M89.91 Disorder of bone, unspecified (Shoulder region)	0.003	0.997	0.000
M89.90 Disorder of bone, unspecified (Multiple sites)	0.003	0.997	0.000
M89.03 Algoneurodystrophy (Forearm)	0.003	0.997	0.000
E88 Other metabolic disorders	0.000	0.997	0.003
E70-E90 Metabolic disorders	0.000	0.997	0.003
G72.9 Myopathy, unspecified	0.003	0.997	0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
N64.4 Mastodynia	0.003	0.997	0.000
N64.9 Disorder of breast, unspecified	0.003	0.997	0.000
C64 Malignant neoplasm of kidney, except renal pelvis	0.003	0.997	0.000
M89.37 Hypertrophy of bone (Ankle and foot)	0.002	0.997	0.000
E74 Other disorders of carbohydrate metabolism	0.000	0.997	0.003
E85 Amyloidosis	0.000	0.997	0.003
M89.39 Hypertrophy of bone (Site unspecified)	0.002	0.997	0.000
M89.38 Hypertrophy of bone (Other)	0.002	0.997	0.000
M89.36 Hypertrophy of bone (Lower leg)	0.002	0.997	0.000
M89.35 Hypertrophy of bone (Pelvic region and thigh)	0.002	0.997	0.000
M89.34 Hypertrophy of bone (Hand)	0.002	0.997	0.000
M89.33 Hypertrophy of bone (Forearm)	0.002	0.997	0.000
M89.32 Hypertrophy of bone (Upper arm)	0.002	0.997	0.000
M89.31 Hypertrophy of bone (Shoulder region)	0.002	0.997	0.000
M89.30 Hypertrophy of bone (Multiple sites)	0.002	0.997	0.000
N64.3 Galactorrhoea not associated with childbirth	0.002	0.997	0.000
N64.2 Atrophy of breast	0.002	0.997	0.000
N64.0 Fissure and fistula of nipple	0.002	0.997	0.000
R30.0 Dysuria	0.003	0.997	0.000
M89.19 Epiphyseal arrest (Site unspecified)	0.002	0.997	0.000
M89.18 Epiphyseal arrest (Other)	0.002	0.997	0.000
M89.17 Epiphyseal arrest (Ankle and foot)	0.002	0.997	0.000
M89.16 Epiphyseal arrest (Lower leg)	0.002	0.997	0.000
M89.15 Epiphyseal arrest (Pelvic region and thigh)	0.002	0.997	0.000
M89.14 Epiphyseal arrest (Hand)	0.002	0.997	0.000
M89.13 Epiphyseal arrest (Forearm)	0.002	0.997	0.000
M89.12 Epiphyseal arrest (Upper arm)	0.002	0.997	0.000
M89.11 Epiphyseal arrest (Shoulder region)	0.002	0.997	0.000
M89.10 Epiphyseal arrest (Multiple sites)	0.002	0.997	0.000
M89.29 Other disorders of bone development and growth (Site unspecified)	0.002	0.997	0.000
M89.28 Other disorders of bone development and growth (Other)	0.002	0.997	0.000
M89.27 Other disorders of bone development and growth (Ankle and foot)	0.002	0.997	0.000
M89.26 Other disorders of bone development and growth (Lower leg)	0.002	0.997	0.000
M89.25 Other disorders of bone development and growth (Pelvic region and thigh)	0.002	0.997	0.000
M89.24 Other disorders of bone development and growth (Hand)	0.002	0.997	0.000
M89.23 Other disorders of bone development and growth (Forearm)	0.002	0.997	0.000
M89.22 Other disorders of bone development and growth (Upper arm)	0.002	0.997	0.000
M89.21 Other disorders of bone development and growth (Shoulder region)	0.002	0.997	0.000
M89.20 Other disorders of bone development and growth (Multiple sites)	0.002	0.997	0.000
M89.49 Other hypertrophic osteoarthropathy (Site unspecified)	0.002	0.997	0.000
M89.48 Other hypertrophic osteoarthropathy (Other)	0.002	0.997	0.000
M89.47 Other hypertrophic osteoarthropathy (Ankle and foot)	0.002	0.997	0.000
M89.46 Other hypertrophic osteoarthropathy (Lower leg)	0.002	0.997	0.000
M89.45 Other hypertrophic osteoarthropathy (Pelvic region and thigh)	0.002	0.997	0.000
M89.44 Other hypertrophic osteoarthropathy (Hand)	0.002	0.997	0.000
M89.43 Other hypertrophic osteoarthropathy (Forearm)	0.002	0.997	0.000
M89.42 Other hypertrophic osteoarthropathy (Upper arm)	0.002	0.997	0.000
M89.41 Other hypertrophic osteoarthropathy (Shoulder region)	0.002	0.997	0.000
M89.40 Other hypertrophic osteoarthropathy (Multiple sites)	0.002	0.997	0.000
M89.69 Osteopathy after poliomyelitis (Site unspecified)	0.002	0.997	0.000
M89.68 Osteopathy after poliomyelitis (Other)	0.002	0.997	0.000
M89.67 Osteopathy after poliomyelitis (Ankle and foot)	0.002	0.997	0.000
M89.66 Osteopathy after poliomyelitis (Lower leg)	0.002	0.997	0.000
M89.65 Osteopathy after poliomyelitis (Pelvic region and thigh)	0.002	0.997	0.000
M89.64 Osteopathy after poliomyelitis (Hand)	0.002	0.997	0.000
M89.63 Osteopathy after poliomyelitis (Forearm)	0.002	0.997	0.000
M89.62 Osteopathy after poliomyelitis (Upper arm)	0.002	0.997	0.000
M89.61 Osteopathy after poliomyelitis (Shoulder region)	0.002	0.997	0.000
M89.60 Osteopathy after poliomyelitis (Multiple sites)	0.002	0.997	0.000
Z99.3 Dependence on wheelchair	0.000	0.997	0.003
M89.59 Osteolysis (Site unspecified)	0.002	0.997	0.000
M89.58 Osteolysis (Other)	0.002	0.997	0.000
M89.57 Osteolysis (Ankle and foot)	0.002	0.997	0.000
M89.56 Osteolysis (Lower leg)	0.002	0.997	0.000
M89.54 Osteolysis (Hand)	0.002	0.997	0.000
M89.53 Osteolysis (Forearm)	0.002	0.997	0.000
M89.52 Osteolysis (Upper arm)	0.002	0.997	0.000
M89.51 Osteolysis (Shoulder region)	0.002	0.997	0.000
M89.50 Osteolysis (Multiple sites)	0.002	0.997	0.000
E74.3 Other disorders of intestinal carbohydrate absorption	0.000	0.997	0.002
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.002	0.997	0.000
M89.55 Osteolysis (Pelvic region and thigh)	0.002	0.997	0.000
M13.00 Polyarthritis, unspecified (Multiple sites)	0.002	0.997	0.000
E73 Lactose intolerance	0.000	0.998	0.002
C43.3 Malignant melanoma of other and unspecified parts of face	0.001	0.998	0.002
E85.9 Amyloidosis, unspecified	0.000	0.998	0.002
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.998	0.002
E84 Cystic fibrosis	0.000	0.998	0.002
E79 Disorders of purine and pyrimidine metabolism	0.000	0.998	0.002
E77 Disorders of glycoprotein metabolism	0.000	0.998	0.002
E76 Disorders of glycosaminoglycan metabolism	0.000	0.998	0.002
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.998	0.002
E72 Other disorders of amino-acid metabolism	0.000	0.998	0.002
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.998	0.002
E70 Disorders of aromatic amino-acid metabolism	0.000	0.998	0.002
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.998	0.002
E88.9 Metabolic disorder, unspecified	0.000	0.998	0.002
E88.8 Other specified metabolic disorders	0.000	0.998	0.002
E88.3 Tumour lysis syndrome	0.000	0.998	0.002
E88.1 Lipodystrophy, not elsewhere classified	0.000	0.998	0.002
S92.00 Fracture of calcaneus (closed)	0.002	0.998	0.000
E85.4 Organ-limited amyloidosis	0.000	0.998	0.002
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.000	0.998	0.002
E88.2 Lipomatosis, not elsewhere classified	0.000	0.998	0.002
E73.9 Lactose intolerance, unspecified	0.000	0.998	0.002
I85.0 Oesophageal varices with bleeding	0.002	0.998	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.002	0.998	0.000
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.998	0.002
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.998	0.002
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.998	0.002
E74.2 Disorders of galactose metabolism	0.000	0.998	0.002
E74.1 Disorders of fructose metabolism	0.000	0.998	0.002
E74.0 Glycogen storage disease	0.000	0.998	0.002
E85.8 Other amyloidosis	0.000	0.998	0.002
E85.3 Secondary systemic amyloidosis	0.000	0.998	0.002
E85.2 Heredofamilial amyloidosis, unspecified	0.000	0.998	0.002
E85.1 Neuropathic heredofamilial amyloidosis	0.000	0.998	0.002
E85.0 Nonneuropathic heredofamilial amyloidosis	0.000	0.998	0.002
O72.1 Other immediate postpartum haemorrhage	0.000	0.998	0.002
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.000	0.998	0.002
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
O32.1 Maternal care for breech presentation	0.002	0.998	0.000
I21.4 Acute subendocardial myocardial infarction	0.000	0.998	0.002
E73.8 Other lactose intolerance	0.000	0.998	0.002
E73.1 Secondary lactase deficiency	0.000	0.998	0.002
E73.0 Congenital lactase deficiency	0.000	0.998	0.002
E80.4 Gilbert's syndrome	0.000	0.998	0.002
C50.1 Central portion of breast	0.000	0.998	0.002
E80.7 Disorder of bilirubin metabolism, unspecified	0.000	0.998	0.002
E80.6 Other disorders of bilirubin metabolism	0.000	0.998	0.002
E80.5 Crigler-Najjar syndrome	0.000	0.998	0.002
E80.3 Defects of catalase and peroxydase	0.000	0.998	0.002
E80.2 Other porphyria	0.000	0.998	0.002
E80.1 Porphyria cutanea tarda	0.000	0.998	0.002
E80.0 Hereditary erythropoietic porphyria	0.000	0.998	0.002
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.000	0.998	0.002
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.998	0.002
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.998	0.002
E70.3 Albinism	0.000	0.998	0.002
E70.2 Disorders of tyrosine metabolism	0.000	0.998	0.002
E70.1 Other hyperphenylalaninaemias	0.000	0.998	0.002
E70.0 Classical phenylketonuria	0.000	0.998	0.002
E71.3 Disorders of fatty-acid metabolism	0.000	0.998	0.002
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.998	0.002
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.998	0.002
E71.0 Maple-syrup-urine disease	0.000	0.998	0.002
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.998	0.002
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.998	0.002
E72.5 Disorders of glycine metabolism	0.000	0.998	0.002
E72.4 Disorders of ornithine metabolism	0.000	0.998	0.002
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.998	0.002
E72.2 Disorders of urea cycle metabolism	0.000	0.998	0.002
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.998	0.002
E72.0 Disorders of amino-acid transport	0.000	0.998	0.002
E75.6 Lipid storage disorder, unspecified	0.000	0.998	0.002
E75.5 Other lipid storage disorders	0.000	0.998	0.002
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.998	0.002
E75.3 Sphingolipidosis, unspecified	0.000	0.998	0.002
E75.2 Other sphingolipidosis	0.000	0.998	0.002
E75.1 Other gangliosidosis	0.000	0.998	0.002
E75.0 GM2 gangliosidosis	0.000	0.998	0.002
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.998	0.002
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.998	0.002
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.998	0.002
E76.2 Other mucopolysaccharidoses	0.000	0.998	0.002
E76.1 Mucopolysaccharidosis, type II	0.000	0.998	0.002
E76.0 Mucopolysaccharidosis, type I	0.000	0.998	0.002
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.998	0.002
E77.8 Other disorders of glycoprotein metabolism	0.000	0.998	0.002
E77.1 Defects in glycoprotein degradation	0.000	0.998	0.002
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.998	0.002
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.998	0.002
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.998	0.002
E79.1 Lesch-Nyhan syndrome	0.000	0.998	0.002
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.998	0.002
E84.9 Cystic fibrosis, unspecified	0.000	0.998	0.002
E84.8 Cystic fibrosis with other manifestations	0.000	0.998	0.002
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.998	0.002
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.998	0.002
M86-M90 Other osteopathies	0.002	0.998	0.000
E83 Disorders of mineral metabolism	0.000	0.998	0.002
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.000	0.998	0.002
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.000	0.998	0.002
T83.2 Mechanical complication of graft of urinary organ	0.000	0.998	0.002
T83.0 Mechanical complication of urinary (indwelling) catheter	0.000	0.998	0.002
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
E83.4 Disorders of magnesium metabolism	0.000	0.998	0.002
M87 Osteonecrosis	0.002	0.998	0.000
R06 Abnormalities of breathing	0.000	0.998	0.002
G97.1 Other reaction to spinal and lumbar puncture	0.000	0.998	0.002
I25.9 Chronic ischaemic heart disease, unspecified	0.000	0.998	0.002
M90 Osteopathies in diseases classified elsewhere	0.002	0.998	0.000
O72.2 Delayed and secondary postpartum haemorrhage	0.000	0.998	0.002
R06.1 Stridor	0.000	0.998	0.002
T22.0 Burn of unspecified degree of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
H21.5 Other adhesions and disruptions of iris and ciliary body	0.002	0.998	0.000
M87.1 Osteonecrosis due to drugs	0.002	0.998	0.000
T22.3 Burn of third degree of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.002	0.998	0.000
H11.4 Other conjunctival vascular disorders and cysts	0.000	0.998	0.002
K26.5 Chronic or unspecified with perforation	0.002	0.998	0.000
M16.0 Primary coxarthrosis, bilateral	0.002	0.998	0.000
M25.51 Pain in joint (Shoulder region)	0.000	0.998	0.002
M87.15 Osteonecrosis due to drugs (Pelvic region and thigh)	0.002	0.998	0.000
E89.2 Postprocedural hypoparathyroidism	0.000	0.998	0.002
M87.2 Osteonecrosis due to previous trauma	0.002	0.998	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.998	0.002
E83.8 Other disorders of mineral metabolism	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations