TreeWAS – Variant ID: rs12207404

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K90.0 Coeliac disease	0.000	0.000	1.000
L40.9 Psoriasis, unspecified	1.000	0.000	0.000
L40.5 Arthropathic psoriasis	1.000	0.000	0.000
L40 Psoriasis	1.000	0.000	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	1.000	0.000	0.000
L40.0 Psoriasis vulgaris	1.000	0.000	0.000
E03.9 Hypothyroidism, unspecified	0.000	0.000	1.000
E00-E07 Disorders of thyroid gland	0.000	0.000	1.000
E03 Other hypothyroidism	0.000	0.000	1.000
M07.3 Other psoriatic arthropathies	0.999	0.001	0.000
E10 Insulin-dependent diabetes mellitus	0.000	0.001	0.999
E10.9 Without complications	0.000	0.001	0.999
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.002	0.998
E10-E14 Diabetes mellitus	0.000	0.007	0.993
M07.30 Other psoriatic arthropathies (Multiple sites)	0.992	0.008	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.008	0.992
E05.9 Thyrotoxicosis, unspecified	0.000	0.011	0.989
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.023	0.977
E10.3 With ophthalmic complications	0.000	0.063	0.937
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.079	0.921
E07 Other disorders of thyroid	0.000	0.090	0.910
E10.4 With neurological complications	0.000	0.094	0.906
E16 Other disorders of pancreatic internal secretion	0.000	0.130	0.870
M07.34 Other psoriatic arthropathies (Hand)	0.867	0.133	0.000
M07.38 Other psoriatic arthropathies (Other)	0.865	0.135	0.000
L40.8 Other psoriasis	0.861	0.139	0.000
L40.1 Generalised pustular psoriasis	0.859	0.141	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.853	0.147	0.000
E07.9 Disorder of thyroid, unspecified	0.000	0.157	0.843
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.843	0.157	0.000
E16.2 Hypoglycaemia, unspecified	0.000	0.160	0.840
E10.1 With ketoacidosis	0.000	0.162	0.838
E10.2 With renal complications	0.000	0.169	0.831
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.822	0.178	0.000
L40.4 Guttate psoriasis	0.821	0.178	0.000
E10.5 With peripheral circulatory complications	0.000	0.215	0.785
E14 Unspecified diabetes mellitus	0.000	0.224	0.776
E10.8 With unspecified complications	0.000	0.276	0.724
L40.3 Pustulosis palmaris et plantaris	0.717	0.283	0.000
L40.2 Acrodermatitis continua	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.283	0.717
E00 Congenital iodine-deficiency syndrome	0.000	0.283	0.717
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.283	0.717
E03.5 Myxoedema coma	0.000	0.283	0.717
E03.4 Atrophy of thyroid (acquired)	0.000	0.283	0.717
E03.3 Postinfectious hypothyroidism	0.000	0.283	0.717
E03.1 Congenital hypothyroidism without goitre	0.000	0.283	0.717
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.283	0.717
M07.33 Other psoriatic arthropathies (Forearm)	0.716	0.284	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.716	0.284	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.716	0.284	0.000
E10.7 With multiple complications	0.000	0.284	0.716
E10.6 With other specified complications	0.000	0.284	0.716
E10.0 With coma	0.000	0.284	0.716
E05.8 Other thyrotoxicosis	0.000	0.284	0.716
E05.5 Thyroid crisis or storm	0.000	0.284	0.716
E05.4 Thyrotoxicosis factitia	0.000	0.284	0.716
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.284	0.716
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.284	0.716
E12 Malnutrition-related diabetes mellitus	0.000	0.288	0.712
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.291	0.709
E14.3 With ophthalmic complications	0.000	0.303	0.697
E07.8 Other specified disorders of thyroid	0.000	0.339	0.661
E15 Nondiabetic hypoglycaemic coma	0.000	0.340	0.660
E07.1 Dyshormogenetic goitre	0.000	0.347	0.652
E07.0 Hypersecretion of calcitonin	0.000	0.347	0.652
E06 Thyroiditis	0.000	0.349	0.651
E40-E46 Malnutrition	0.000	0.357	0.643
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.376	0.623
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.376	0.623
E16.4 Abnormal secretion of gastrin	0.000	0.376	0.623
E16.3 Increased secretion of glucagon	0.000	0.376	0.623
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.376	0.623
E13 Other specified diabetes mellitus	0.000	0.382	0.618
E20-E35 Disorders of other endocrine glands	0.000	0.393	0.607
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.420	0.580
E04 Other non-toxic goitre	0.000	0.421	0.579
E16.1 Other hypoglycaemia	0.000	0.437	0.563
E14.8 With unspecified complications	0.000	0.443	0.557
E14.7 With multiple complications	0.000	0.443	0.557
E14.6 With other specified complications	0.000	0.443	0.557
E14.5 With peripheral circulatory complications	0.000	0.443	0.557
E14.2 Withrenal complications	0.000	0.443	0.557
E14.1 With ketoacidosis	0.000	0.443	0.557
E14.0 With coma	0.000	0.443	0.557
E65-E68 Obesity and other hyperalimentation	0.000	0.469	0.531
E03.8 Other specified hypothyroidism	0.000	0.475	0.524
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.486	0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.486	0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.486	0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.486	0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.486	0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.486	0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.486	0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.486	0.514
E12.9 Without complications	0.000	0.489	0.510
E12.8 With unspecified complications	0.000	0.489	0.510
E12.7 With multiple complications	0.000	0.489	0.510
E12.6 With other specified complications	0.000	0.489	0.510
E12.5 With peripheral circulatory complications	0.000	0.489	0.510
E12.4 With neurological complications	0.000	0.489	0.510
E12.3 With ophthalmic complications	0.000	0.489	0.510
E12.2 With renal complications	0.000	0.489	0.510
E12.1 With ketoacidosis	0.000	0.489	0.510
E12.0 With coma	0.000	0.489	0.510
E29 Testicular dysfunction	0.000	0.500	0.500
E14.4 With neurological complications	0.000	0.503	0.497
E04.9 Non-toxic goitre, unspecified	0.000	0.507	0.493
E27 Other disorders of adrenal gland	0.000	0.508	0.492
E28 Ovarian dysfunction	0.000	0.519	0.480
E27.1 Primary adrenocortical insufficiency	0.000	0.533	0.467
E06.5 Other chronic thyroiditis	0.000	0.533	0.466
E06.4 Drug-induced thyroiditis	0.000	0.533	0.466
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.533	0.466
E06.1 Subacute thyroiditis	0.000	0.533	0.466
E06.0 Acute thyroiditis	0.000	0.533	0.466
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.539	0.461
E45 Retarded development following protein-energy malnutrition	0.000	0.539	0.461
E43 Unspecified severe protein-energy malnutrition	0.000	0.539	0.461
E42 Marasmic kwashiorkor	0.000	0.539	0.461
E41 Nutritional marasmus	0.000	0.539	0.461
E40 Kwashiorkor	0.000	0.539	0.461
E06.9 Thyroiditis, unspecified	0.000	0.541	0.459
E34 Other endocrine disorders	0.000	0.542	0.458
E50-E64 Other nutritional deficiencies	0.000	0.556	0.444
E13.8 With unspecified complications	0.000	0.557	0.443
E13.7 With multiple complications	0.000	0.557	0.443
E13.6 With other specified complications	0.000	0.557	0.443
E13.5 With peripheral circulatory complications	0.000	0.557	0.443
E13.4 With neurological complications	0.000	0.557	0.443
E13.3 With ophthalmic complications	0.000	0.557	0.443
E13.2 With renal complications	0.000	0.557	0.443
E13.1 With ketoacidosis	0.000	0.557	0.443
E13.0 With coma	0.000	0.557	0.443
E26 Hyperaldosteronism	0.000	0.561	0.439
E14.9 Without complications	0.000	0.562	0.438
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.565	0.435
E32 Diseases of thymus	0.000	0.565	0.435
E31 Polyglandular dysfunction	0.000	0.565	0.435
E30 Disorders of puberty, not elsewhere classified	0.000	0.565	0.435
E20 Hypoparathyroidism	0.000	0.565	0.435
M07 Psoriatic and enteropathic arthropathies	0.423	0.575	0.002
E29.1 Testicular hypofunction	0.000	0.576	0.424
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.581	0.419
E04.8 Other specified non-toxic goitre	0.000	0.585	0.415
E22 Hyperfunction of pituitary gland	0.000	0.588	0.412
E06.3 Autoimmune thyroiditis	0.000	0.589	0.410
K90 Intestinal malabsorption	0.000	0.607	0.393
E46 Unspecified protein-energy malnutrition	0.000	0.607	0.393
E65 Localised adiposity	0.000	0.612	0.388
E28.2 Polycystic ovarian syndrome	0.000	0.616	0.384
E67 Other hyperalimentation	0.000	0.619	0.381
E68 Sequelae of hyperalimentation	0.000	0.619	0.381
E29.9 Testicular dysfunction, unspecified	0.000	0.641	0.359
E29.8 Other testicular dysfunction	0.000	0.641	0.359
E29.0 Testicular hyperfunction	0.000	0.641	0.359
E04.0 Non-toxic diffuse goitre	0.000	0.646	0.353
E27.5 Adrenomedullary hyperfunction	0.000	0.647	0.353
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.647	0.353
E27.0 Other adrenocortical overactivity	0.000	0.647	0.353
E28.3 Primary ovarian failure	0.000	0.647	0.353
E25 Adrenogenital disorders	0.001	0.648	0.351
E13.9 Without complications	0.000	0.651	0.349
E24 Cushing's syndrome	0.000	0.653	0.346
E28.9 Ovarian dysfunction, unspecified	0.000	0.655	0.345
E28.8 Other ovarian dysfunction	0.000	0.655	0.345
E28.1 Androgen excess	0.000	0.655	0.345
E28.0 Oestrogen excess	0.000	0.655	0.345
E34.9 Endocrine disorder, unspecified	0.000	0.656	0.344
E27.2 Addisonian crisis	0.000	0.662	0.338
E34.0 Carcinoid syndrome	0.000	0.663	0.337
E44.1 Mild protein-energy malnutrition	0.000	0.669	0.330
E44.0 Moderate protein-energy malnutrition	0.000	0.669	0.330
E34.8 Other specified endocrine disorders	0.000	0.671	0.329
E34.5 Androgen resistance syndrome	0.000	0.671	0.329
E34.4 Constitutional tall stature	0.000	0.671	0.329
E34.3 Short stature, not elsewhere classified	0.000	0.671	0.329
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.671	0.329
E34.1 Other hypersecretion of intestinal hormones	0.000	0.671	0.329
E04.1 Non-toxic single thyroid nodule	0.000	0.672	0.328
E21.0 Primary hyperparathyroidism	0.000	0.677	0.323
E22.1 Hyperprolactinaemia	0.000	0.679	0.321
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.682	0.318
E63 Other nutritional deficiencies	0.000	0.682	0.318
E56 Other vitamin deficiencies	0.000	0.682	0.318
E51 Thiamine deficiency	0.000	0.682	0.318
E50 Vitamin A deficiency	0.000	0.682	0.318
E60 Dietary zinc deficiency	0.000	0.682	0.318
E59 Dietary selenium deficiency	0.000	0.682	0.318
E58 Dietary calcium deficiency	0.000	0.682	0.318
E54 Ascorbic acid deficiency	0.000	0.682	0.318
E52 Niacin deficiency [pellagra]	0.000	0.682	0.318
E26.0 Primary hyperaldosteronism	0.000	0.682	0.318
E26.9 Hyperaldosteronism, unspecified	0.000	0.685	0.314
E26.8 Other hyperaldosteronism	0.000	0.685	0.314
E26.1 Secondary hyperaldosteronism	0.000	0.685	0.314
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.685	0.314
E22.0 Acromegaly and pituitary gigantism	0.000	0.687	0.313
E20.9 Hypoparathyroidism, unspecified	0.000	0.688	0.312
E20.8 Other hypoparathyroidism	0.000	0.688	0.312
E20.1 Pseudohypoparathyroidism	0.000	0.688	0.312
E20.0 Idiopathic hypoparathyroidism	0.000	0.688	0.312
E30.9 Disorder of puberty, unspecified	0.000	0.688	0.312
E30.8 Other disorders of puberty	0.000	0.688	0.312
E30.1 Precocious puberty	0.000	0.688	0.312
E30.0 Delayed puberty	0.000	0.688	0.312
E31.9 Polyglandular dysfunction, unspecified	0.000	0.688	0.312
E31.8 Other polyglandular dysfunction	0.000	0.688	0.312
E31.1 Polyglandular hyperfunction	0.000	0.688	0.312
E31.0 Autoimmune polyglandular failure	0.000	0.688	0.312
E32.9 Disease of thymus, unspecified	0.000	0.688	0.312
E32.8 Other diseases of thymus	0.000	0.688	0.312
E32.1 Abscess of thymus	0.000	0.688	0.312
E32.0 Persistent hyperplasia of thymus	0.000	0.688	0.312
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.688	0.312
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.688	0.312
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.688	0.312
E04.2 Non-toxic multinodular goitre	0.000	0.692	0.308
M07.6 Other enteropathic arthropathies	0.303	0.695	0.001
M07.5 Arthropathy in ulcerative colitis	0.303	0.695	0.001
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.303	0.695	0.001
M07.2 Psoriatic spondylitis	0.303	0.695	0.001
M07.1 Arthritis mutilans	0.303	0.695	0.001
M07.0 Distal interphalangeal psoriatic arthropathy	0.303	0.695	0.001
E61 Deficiency of other nutrient elements	0.000	0.696	0.304
E27.9 Disorder of adrenal gland, unspecified	0.000	0.699	0.301
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.700	0.300
E21.4 Other specified disorders of parathyroid gland	0.000	0.700	0.300
E21.2 Other hyperparathyroidism	0.000	0.700	0.300
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.704	0.295
E22.8 Other hyperfunction of pituitary gland	0.000	0.704	0.295
K90.8 Other intestinal malabsorption	0.000	0.718	0.282
K90.3 Pancreatic steatorrhoea	0.000	0.718	0.282
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.718	0.282
K90.1 Tropical sprue	0.000	0.718	0.282
E21.3 Hyperparathyroidism, unspecified	0.000	0.718	0.282
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.724	0.276
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.725	0.275
E67.8 Other specified hyperalimentation	0.000	0.727	0.273
E67.3 Hypervitaminosis D	0.000	0.727	0.273
E67.2 Megavitamin-B6 syndrome	0.000	0.727	0.273
E67.1 Hypercarotenaemia	0.000	0.727	0.273
E67.0 Hypervitaminosis A	0.000	0.727	0.273
E27.8 Other specified disorders of adrenal gland	0.000	0.735	0.264
K90.9 Intestinal malabsorption, unspecified	0.000	0.740	0.259
L40-L45 Papulosquamous disorders	0.254	0.746	0.000
E25.9 Adrenogenital disorder, unspecified	0.001	0.747	0.252
E25.8 Other adrenogenital disorders	0.001	0.747	0.252
E24.8 Other Cushing's syndrome	0.000	0.751	0.248
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.751	0.248
E24.3 Ectopic ACTH syndrome	0.000	0.751	0.248
E24.2 Drug-induced Cushing's syndrome	0.000	0.751	0.248
E24.1 Nelson's syndrome	0.000	0.751	0.248
E55 Vitamin D deficiency	0.000	0.763	0.237
E53 Deficiency of other B group vitamins	0.000	0.770	0.230
E24.9 Cushing's syndrome, unspecified	0.000	0.771	0.229
E50.9 Vitamin A deficiency, unspecified	0.000	0.772	0.228
E50.8 Other manifestations of vitamin A deficiency	0.000	0.772	0.228
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.772	0.228
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.772	0.228
E50.5 Vitamin A deficiency with night blindness	0.000	0.772	0.228
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.772	0.228
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.772	0.228
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.772	0.228
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.772	0.228
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.772	0.228
E51.9 Thiamine deficiency, unspecified	0.000	0.772	0.228
E51.8 Other manifestations of thiamine deficiency	0.000	0.772	0.228
E51.2 Wernicke's encephalopathy	0.000	0.772	0.228
E51.1 Beriberi	0.000	0.772	0.228
E56.9 Vitamin deficiency, unspecified	0.000	0.772	0.228
E56.8 Deficiency of other vitamins	0.000	0.772	0.228
E56.1 Deficiency of vitamin K	0.000	0.772	0.228
E56.0 Deficiency of vitamin E	0.000	0.772	0.228
E63.9 Nutritional deficiency, unspecified	0.000	0.772	0.228
E63.8 Other specified nutritional deficiencies	0.000	0.772	0.228
E63.1 Imbalance of constituents of food intake	0.000	0.772	0.228
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.772	0.228
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.772	0.228
E64.8 Sequelae of other nutritional deficiencies	0.000	0.772	0.228
E64.3 Sequelae of rickets	0.000	0.772	0.228
E64.2 Sequelae of vitamin C deficiency	0.000	0.772	0.228
E64.1 Sequelae of vitamin A deficiency	0.000	0.772	0.228
E64.0 Sequelae of protein-energy malnutrition	0.000	0.772	0.228
E23 Hypofunction and other disorders of pituitary gland	0.001	0.775	0.224
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)	0.218	0.781	0.001
M07.08 Distal interphalangeal proriatic arthropathy-Other	0.218	0.781	0.001
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)	0.218	0.781	0.001
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg	0.218	0.781	0.001
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh	0.218	0.781	0.001
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)	0.218	0.781	0.001
M07.03 Distal interphalangeal proriatic arthropathy-Forearm	0.218	0.781	0.001
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm	0.218	0.781	0.001
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region	0.218	0.781	0.001
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)	0.218	0.781	0.001
M07.19 Arthritis mutilans (Site unspecified)	0.218	0.781	0.001
M07.18 Arthritis mutilans (Other)	0.218	0.781	0.001
M07.17 Arthritis mutilans (Ankle and foot)	0.218	0.781	0.001
M07.16 Arthritis mutilans (Lower leg)	0.218	0.781	0.001
M07.15 Arthritis mutilans (Pelvic region and thigh)	0.218	0.781	0.001
M07.14 Arthritis mutilans (Hand)	0.218	0.781	0.001
M07.13 Arthritis mutilans (Forearm)	0.218	0.781	0.001
M07.12 Arthritis mutilans (Upper arm)	0.218	0.781	0.001
M07.11 Arthritis mutilans (Shoulder region)	0.218	0.781	0.001
M07.10 Arthritis mutilans (Multiple sites)	0.218	0.781	0.001
M07.29 Psoriatic spondylitis (Site unspecified)	0.218	0.781	0.001
M07.28 Psoriatic spondylitis (Other)	0.218	0.781	0.001
M07.27 Psoriatic spondylitis (Ankle and foot)	0.218	0.781	0.001
M07.26 Psoriatic spondylitis (Lower leg)	0.218	0.781	0.001
M07.25 Psoriatic spondylitis (Pelvic region and thigh)	0.218	0.781	0.001
M07.24 Psoriatic spondylitis (Hand)	0.218	0.781	0.001
M07.23 Psoriatic spondylitis (Forearm)	0.218	0.781	0.001
M07.22 Psoriatic spondylitis (Upper arm)	0.218	0.781	0.001
M07.21 Psoriatic spondylitis (Shoulder region)	0.218	0.781	0.001
M07.20 Psoriatic spondylitis (Multiple sites)	0.218	0.781	0.001
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)	0.218	0.781	0.001
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)	0.218	0.781	0.001
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)	0.218	0.781	0.001
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)	0.218	0.781	0.001
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)	0.218	0.781	0.001
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)	0.218	0.781	0.001
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)	0.218	0.781	0.001
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)	0.218	0.781	0.001
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)	0.218	0.781	0.001
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)	0.218	0.781	0.001
M07.59 Arthropathy in ulcerative colitis (Site unspecified)	0.218	0.781	0.001
M07.58 Arthropathy in ulcerative colitis (Other)	0.218	0.781	0.001
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)	0.218	0.781	0.001
M07.56 Arthropathy in ulcerative colitis (Lower leg)	0.218	0.781	0.001
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)	0.218	0.781	0.001
M07.54 Arthropathy in ulcerative colitis (Hand)	0.218	0.781	0.001
M07.53 Arthropathy in ulcerative colitis (Forearm)	0.218	0.781	0.001
M07.52 Arthropathy in ulcerative colitis (Upper arm)	0.218	0.781	0.001
M07.51 Arthropathy in ulcerative colitis (Shoulder region)	0.218	0.781	0.001
M07.50 Arthropathy in ulcerative colitis (Multiple sites)	0.218	0.781	0.001
M07.69 Other enteropathic arthropathies (Site unspecified)	0.218	0.781	0.001
M07.68 Other enteropathic arthropathies (Other)	0.218	0.781	0.001
M07.67 Other enteropathic arthropathies (Ankle and foot)	0.218	0.781	0.001
M07.66 Other enteropathic arthropathies (Lower leg)	0.218	0.781	0.001
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)	0.218	0.781	0.001
M07.64 Other enteropathic arthropathies (Hand)	0.218	0.781	0.001
M07.63 Other enteropathic arthropathies (Forearm)	0.218	0.781	0.001
M07.62 Other enteropathic arthropathies (Upper arm)	0.218	0.781	0.001
M07.61 Other enteropathic arthropathies (Shoulder region)	0.218	0.781	0.001
M07.60 Other enteropathic arthropathies (Multiple sites)	0.218	0.781	0.001
E61.9 Deficiency of nutrient element, unspecified	0.000	0.782	0.218
E61.8 Deficiency of other specified nutrient elements	0.000	0.782	0.218
E61.7 Deficiency of multiple nutrient elements	0.000	0.782	0.218
E61.6 Vanadium deficiency	0.000	0.782	0.218
E61.5 Molybdenum deficiency	0.000	0.782	0.218
E61.4 Chromium deficiency	0.000	0.782	0.218
E61.3 Manganese deficiency	0.000	0.782	0.218
E61.2 Magnesium deficiency	0.000	0.782	0.218
E61.0 Copper deficiency	0.000	0.782	0.218
E61.1 Iron deficiency	0.000	0.797	0.203
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.797	0.203
E24.0 Pituitary-dependent Cushing's disease	0.001	0.809	0.191
L42 Pityriasis rosea	0.184	0.816	0.000
E66 Obesity	0.000	0.817	0.183
L44 Other papulosquamous disorders	0.182	0.818	0.000
L41 Parapsoriasis	0.182	0.818	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.182	0.818	0.000
E55.0 Rickets, active	0.000	0.830	0.170
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.001	0.831	0.168
E23.2 Diabetes insipidus	0.001	0.831	0.169
E53.9 Vitamin B deficiency, unspecified	0.000	0.835	0.165
E53.1 Pyridoxine deficiency	0.000	0.835	0.165
E53.0 Riboflavin deficiency	0.000	0.835	0.165
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.001	0.839	0.161
E23.1 Drug-induced hypopituitarism	0.001	0.839	0.161
E23.6 Other disorders of pituitary gland	0.001	0.848	0.151
E66.8 Other obesity	0.000	0.862	0.138
E66.1 Drug-induced obesity	0.000	0.869	0.131
L41.9 Parapsoriasis, unspecified	0.130	0.869	0.000
L41.8 Other parapsoriasis	0.130	0.869	0.000
L41.5 Retiform parapsoriasis	0.130	0.869	0.000
L41.4 Large plaque parapsoriasis	0.130	0.869	0.000
L41.3 Small plaque parapsoriasis	0.130	0.869	0.000
L41.2 Lymphomatoid papulosis	0.130	0.869	0.000
L41.1 Pityriasis lichenoides chronica	0.130	0.869	0.000
L41.0 Pityriasis lichenoides et varioliformis acuta	0.130	0.869	0.000
L44.9 Papulosquamous disorder, unspecified	0.130	0.869	0.000
L44.8 Other specified papulosquamous disorders	0.130	0.869	0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.130	0.869	0.000
L44.3 Lichen ruber moniliformis	0.130	0.869	0.000
L44.2 Lichen striatus	0.130	0.869	0.000
L44.1 Lichen nitidus	0.130	0.869	0.000
L44.0 Pityriasis rubra pilaris	0.130	0.869	0.000
K50.0 Crohn's disease of small intestine	0.124	0.876	0.000
E66.0 Obesity due to excess calories	0.000	0.882	0.118
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.888	0.112
K50 Crohn's disease [regional enteritis]	0.108	0.892	0.000
E23.7 Disorder of pituitary gland, unspecified	0.001	0.896	0.103
K50.8 Other Crohn's disease	0.101	0.899	0.000
K50.9 Crohn's disease, unspecified	0.101	0.899	0.000
L43 Lichen planus	0.095	0.904	0.001
E55.9 Vitamin D deficiency, unspecified	0.000	0.911	0.088
E11 Non-insulin-dependent diabetes mellitus	0.000	0.914	0.086
E23.0 Hypopituitarism	0.001	0.920	0.079
M35.0 Sicca syndrome [Sjogren]	0.000	0.920	0.080
K83.1 Obstruction of bile duct	0.077	0.923	0.000
E53.8 Deficiency of other specified B group vitamins	0.000	0.924	0.076
L43.3 Subacute (active) lichen planus	0.068	0.931	0.001
L43.2 Lichenoid drug reaction	0.068	0.931	0.001
L43.1 Bullous lichen planus	0.068	0.931	0.001
L43.0 Hypertrophic lichen planus	0.068	0.931	0.001
K83 Other diseases of biliary tract	0.069	0.931	0.000
K83.8 Other specified diseases of biliary tract	0.068	0.932	0.000
M35 Other systemic involvement of connective tissue	0.000	0.932	0.068
E11.8 With unspecified complications	0.000	0.934	0.066
M35.3 Polymyalgia rheumatica	0.000	0.934	0.066
E11.7 With multiple complications	0.000	0.938	0.062
E11.6 With other specified complications	0.000	0.939	0.060
E11.3 With ophthalmic complications	0.000	0.941	0.059
E11.0 With coma	0.000	0.941	0.059
E11.5 With peripheral circulatory complications	0.000	0.942	0.058
K50.1 Crohn's disease of large intestine	0.056	0.944	0.000
L43.8 Other lichen planus	0.055	0.944	0.001
K83.3 Fistula of bile duct	0.053	0.946	0.000
M35.1 Other overlap syndromes	0.000	0.947	0.053
E11.2 With renal complications	0.000	0.947	0.053
K90-K93 Other diseases of the digestive system	0.001	0.949	0.050
K83.0 Cholangitis	0.051	0.949	0.000
K83.9 Disease of biliary tract, unspecified	0.050	0.950	0.000
K83.5 Biliary cyst	0.050	0.950	0.000
K83.4 Spasm of sphincter of Oddi	0.050	0.950	0.000
K83.2 Perforation of bile duct	0.050	0.950	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.000	0.951	0.049
M35.8 Other specified systemic involvement of connective tissue	0.000	0.951	0.049
M35.6 Relapsing panniculitis [Weber-Christian]	0.000	0.951	0.049
M35.5 Multifocal fibrosclerosis	0.000	0.951	0.049
M35.4 Diffuse (eosinophilic) fasciitis	0.000	0.951	0.049
M35.2 Behcet's disease	0.000	0.951	0.049
E70-E90 Metabolic disorders	0.000	0.952	0.048
M35.7 Hypermobility syndrome	0.000	0.954	0.046
E11.1 With ketoacidosis	0.000	0.954	0.046
E73 Lactose intolerance	0.000	0.958	0.042
E85 Amyloidosis	0.000	0.961	0.039
E73.9 Lactose intolerance, unspecified	0.000	0.963	0.037
K93 Disorders of other digestive organs in diseases classified elsewhere	0.001	0.963	0.036
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified	0.000	0.965	0.035
E84 Cystic fibrosis	0.000	0.965	0.035
E79 Disorders of purine and pyrimidine metabolism	0.000	0.965	0.035
E77 Disorders of glycoprotein metabolism	0.000	0.965	0.035
E76 Disorders of glycosaminoglycan metabolism	0.000	0.965	0.035
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.965	0.035
E72 Other disorders of amino-acid metabolism	0.000	0.965	0.035
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.965	0.035
E70 Disorders of aromatic amino-acid metabolism	0.000	0.965	0.035
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.965	0.035
E74 Other disorders of carbohydrate metabolism	0.000	0.966	0.034
E85.9 Amyloidosis, unspecified	0.000	0.967	0.033
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.968	0.032
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.970	0.030
E73.8 Other lactose intolerance	0.000	0.970	0.030
E73.1 Secondary lactase deficiency	0.000	0.970	0.030
E73.0 Congenital lactase deficiency	0.000	0.970	0.030
J47 Bronchiectasis	0.000	0.970	0.030
E85.4 Organ-limited amyloidosis	0.000	0.971	0.029
K91.4 Colostomy and enterostomy malfunction	0.000	0.971	0.029
E85.8 Other amyloidosis	0.000	0.972	0.028
E85.3 Secondary systemic amyloidosis	0.000	0.972	0.028
E85.2 Heredofamilial amyloidosis, unspecified	0.000	0.972	0.028
E85.1 Neuropathic heredofamilial amyloidosis	0.000	0.972	0.028
E85.0 Nonneuropathic heredofamilial amyloidosis	0.000	0.972	0.028
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.001	0.972	0.028
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.001	0.973	0.026
K93.1 Megacolon in Chagas' disease	0.001	0.973	0.026
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.001	0.973	0.026
E89.0 Postprocedural hypothyroidism	0.000	0.975	0.025
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.975	0.025
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.975	0.025
E70.3 Albinism	0.000	0.975	0.025
E70.2 Disorders of tyrosine metabolism	0.000	0.975	0.025
E70.1 Other hyperphenylalaninaemias	0.000	0.975	0.025
E70.0 Classical phenylketonuria	0.000	0.975	0.025
E71.3 Disorders of fatty-acid metabolism	0.000	0.975	0.025
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.975	0.025
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.975	0.025
E71.0 Maple-syrup-urine disease	0.000	0.975	0.025
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.975	0.025
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.975	0.025
E72.5 Disorders of glycine metabolism	0.000	0.975	0.025
E72.4 Disorders of ornithine metabolism	0.000	0.975	0.025
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.975	0.025
E72.2 Disorders of urea cycle metabolism	0.000	0.975	0.025
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.975	0.025
E72.0 Disorders of amino-acid transport	0.000	0.975	0.025
E75.6 Lipid storage disorder, unspecified	0.000	0.975	0.025
E75.5 Other lipid storage disorders	0.000	0.975	0.025
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.975	0.025
E75.3 Sphingolipidosis, unspecified	0.000	0.975	0.025
E75.2 Other sphingolipidosis	0.000	0.975	0.025
E75.1 Other gangliosidosis	0.000	0.975	0.025
E75.0 GM2 gangliosidosis	0.000	0.975	0.025
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.975	0.025
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.975	0.025
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.975	0.025
E76.2 Other mucopolysaccharidoses	0.000	0.975	0.025
E76.1 Mucopolysaccharidosis, type II	0.000	0.975	0.025

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations