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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12216125
log Bayes Factor = 172.493
Chromosome 6   position 25,997,458  (GRCh37) Explore rs12216125 on Ensembl!
Variant rs12216125 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.059 0.941
D64.9 Anaemia, unspecified
0.000 0.540 0.460
K90 Intestinal malabsorption
0.000 0.680 0.320
D45 Polycythaemia vera
0.312 0.688 0.000
D64 Other anaemias
0.000 0.744 0.256
K90.9 Intestinal malabsorption, unspecified
0.000 0.761 0.239
K90.3 Pancreatic steatorrhoea
0.000 0.770 0.229
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.770 0.229
K90.1 Tropical sprue
0.000 0.770 0.229
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.791 0.209
K90.8 Other intestinal malabsorption
0.000 0.804 0.196
D64.4 Congenital dyserythropoietic anaemia
0.000 0.816 0.183
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.816 0.183
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.816 0.183
D64.0 Hereditary sideroblastic anaemia
0.000 0.816 0.183
D60-D64 Aplastic and other anaemias
0.000 0.829 0.171
D64.3 Other sideroblastic anaemias
0.000 0.836 0.164
D64.8 Other specified anaemias
0.000 0.843 0.156
D50.9 Iron deficiency anaemia, unspecified
0.000 0.849 0.151
D50 Iron deficiency anaemia
0.000 0.850 0.150
D50.8 Other iron deficiency anaemias
0.000 0.851 0.149
D62 Acute posthaemorrhagic anaemia
0.000 0.854 0.146
D50-D53 Nutritional anaemias
0.000 0.865 0.135
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.871 0.129
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.877 0.123
D80-D89 Certain disorders involving the immune mechanism
0.000 0.890 0.109
D50.1 Sideropenic dysphagia
0.000 0.892 0.108
D61 Other aplastic anaemias
0.000 0.897 0.103
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.897 0.103
D53 Other nutritional anaemias
0.000 0.905 0.095
D89.2 Hypergammaglobulinaemia, unspecified
0.000 0.905 0.095
L27.0 Generalised skin eruption due to drugs and medicaments
0.000 0.905 0.095
D52 Folate deficiency anaemia
0.000 0.907 0.093
D60.9 Acquired pure red cell aplasia, unspecified
0.000 0.911 0.088
D60.8 Other acquired pure red cell aplasias
0.000 0.911 0.088
D60.1 Transient acquired pure red cell aplasia
0.000 0.911 0.088
D60.0 Chronic acquired pure red cell aplasia
0.000 0.911 0.088
L27 Dermatitis due to substances taken internally
0.000 0.915 0.085
L27.1 Localised skin eruption due to drugs and medicaments
0.000 0.915 0.085
D80 Immunodeficiency with predominantly antibody defects
0.000 0.915 0.084
D89.0 Polyclonal hypergammaglobulinaemia
0.000 0.918 0.082
D84 Other immunodeficiencies
0.000 0.918 0.082
D61.0 Constitutional aplastic anaemia
0.000 0.919 0.081
D89.1 Cryoglobulinaemia
0.000 0.919 0.080
D83 Common variable immunodeficiency
0.000 0.920 0.080
D81 Combined immunodeficiencies
0.000 0.921 0.079
D63 Anaemia in chronic diseases classified elsewhere
0.000 0.922 0.078
D61.1 Drug-induced aplastic anaemia
0.000 0.923 0.077
D61.8 Other specified aplastic anaemias
0.000 0.926 0.074
D61.3 Idiopathic aplastic anaemia
0.000 0.926 0.074
D61.2 Aplastic anaemia due to other external agents
0.000 0.926 0.074
D51 Vitamin B12 deficiency anaemia
0.000 0.926 0.074
D89.3 Immune reconstitution syndrome
0.000 0.926 0.074
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.000 0.928 0.072
D89.9 Disorder involving the immune mechanism, unspecified
0.000 0.929 0.071
D53.8 Other specified nutritional anaemias
0.000 0.931 0.068
D53.2 Scorbutic anaemia
0.000 0.931 0.068
D53.1 Other megaloblastic anaemias, not elsewhere classified
0.000 0.931 0.068
D53.0 Protein deficiency anaemia
0.000 0.931 0.068
D82 Immunodeficiency associated with other major defects
0.000 0.932 0.067
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.933 0.067
D53.9 Nutritional anaemia, unspecified
0.000 0.933 0.067
D55-D59 Haemolytic anaemias
0.000 0.933 0.067
D52.8 Other folate deficiency anaemias
0.000 0.933 0.066
D52.1 Drug-induced folate deficiency anaemia
0.000 0.933 0.066
D52.0 Dietary folate deficiency anaemia
0.000 0.933 0.066
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.000 0.935 0.064
D84.9 Immunodeficiency, unspecified
0.000 0.936 0.064
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.000 0.937 0.063
D52.9 Folate deficiency anaemia, unspecified
0.000 0.937 0.062
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.000 0.938 0.061
L27.9 Dermatitis due to unspecified substance taken internally
0.000 0.939 0.061
L27.8 Dermatitis due to other substances taken internally
0.000 0.939 0.061
D80.8 Other immunodeficiencies with predominantly antibody defects
0.000 0.939 0.061
D80.7 Transient hypogammaglobulinaemia of infancy
0.000 0.939 0.061
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.000 0.939 0.061
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.000 0.939 0.061
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.000 0.939 0.061
D80.0 Hereditary hypogammaglobulinaemia
0.000 0.939 0.061
D80.1 Nonfamilial hypogammaglobulinaemia
0.000 0.940 0.060
D84.8 Other specified immunodeficiencies
0.000 0.940 0.059
D83.9 Common variable immunodeficiency, unspecified
0.000 0.941 0.059
D84.0 Lymphocyte function antigen-1 [LFA-1] defect
0.000 0.941 0.059
L27.2 Dermatitis due to ingested food
0.000 0.941 0.059
D83.8 Other common variable immunodeficiencies
0.000 0.942 0.058
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells
0.000 0.942 0.058
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
0.000 0.942 0.058
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
0.000 0.942 0.058
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.943 0.057
D81.9 Combined immunodeficiency, unspecified
0.000 0.943 0.057
D81.8 Other combined immunodeficiencies
0.000 0.943 0.057
D81.7 Major histocompatibility complex class II deficiency
0.000 0.943 0.057
D81.6 Major histocompatibility complex class I deficiency
0.000 0.943 0.057
D81.5 Purine nucleoside phosphorylase [PNP] deficiency
0.000 0.943 0.057
D81.4 Nezelof's syndrome
0.000 0.943 0.057
D81.3 Adenosine deaminase [ADA] deficiency
0.000 0.943 0.057
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
0.000 0.943 0.057
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
0.000 0.943 0.057
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis
0.000 0.943 0.057
D63.1 Anaemia in other chronic diseases classified elsewhere
0.000 0.943 0.056
D84.1 Defects in the complement system
0.000 0.944 0.056
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.946 0.053
D51.2 Transcobalamin II deficiency
0.000 0.946 0.053
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.946 0.053
D56 Thalassaemia
0.000 0.949 0.051
D63.0 Anaemia in neoplastic disease
0.000 0.950 0.050
E83 Disorders of mineral metabolism
0.047 0.951 0.002
D82.9 Immunodeficiency associated with major defect, unspecified
0.000 0.951 0.048
D82.8 Immunodeficiency associated with other specified major defects
0.000 0.951 0.048
D82.4 Hyperimmunoglobulin E [IgE] syndrome
0.000 0.951 0.048
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus
0.000 0.951 0.048
D82.2 Immunodeficiency with short-limbed stature
0.000 0.951 0.048
D82.0 Wiskott-Aldrich syndrome
0.000 0.951 0.048
D55 Anaemia due to enzyme disorders
0.000 0.952 0.048
D57 Sickle-cell disorders
0.000 0.952 0.047
D86 Sarcoidosis
0.000 0.955 0.045
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.957 0.043
D56.1 Beta thalassaemia
0.000 0.957 0.043
D59 Acquired haemolytic anaemia
0.000 0.960 0.040
E83.9 Disorder of mineral metabolism, unspecified
0.038 0.961 0.001
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.962 0.038
D82.1 Di George's syndrome
0.001 0.963 0.037
D86.8 Sarcoidosis of other and combined sites
0.000 0.963 0.037
D56.9 Thalassaemia, unspecified
0.000 0.963 0.037
D56.8 Other thalassaemias
0.000 0.963 0.037
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]
0.000 0.963 0.037
D56.2 Delta-beta thalassaemia
0.000 0.963 0.037
D56.0 Alpha thalassaemia
0.000 0.963 0.037
E83.8 Other disorders of mineral metabolism
0.034 0.964 0.001
E83.2 Disorders of zinc metabolism
0.034 0.964 0.001
E83.0 Disorders of copper metabolism
0.034 0.964 0.001
D55.9 Anaemia due to enzyme disorder, unspecified
0.000 0.965 0.034
D55.8 Other anaemias due to enzyme disorders
0.000 0.965 0.034
D55.3 Anaemia due to disorders of nucleotide metabolism
0.000 0.965 0.034
D55.2 Anaemia due to disorders of glycolytic enzymes
0.000 0.965 0.034
D55.1 Anaemia due to other disorders of glutathione metabolism
0.000 0.965 0.034
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency
0.000 0.965 0.034
D57.8 Other sickle-cell disorders
0.000 0.966 0.034
D57.3 Sickle-cell trait
0.000 0.966 0.034
D57.2 Double heterozygous sickling disorders
0.000 0.966 0.034
D57.0 Sickle-cell anaemia with crisis
0.000 0.966 0.034
D86.1 Sarcoidosis of lymph nodes
0.000 0.966 0.034
D57.1 Sickle-cell anaemia without crisis
0.000 0.966 0.034
D56.3 Thalassaemia trait
0.000 0.967 0.033
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.967 0.033
D61.9 Aplastic anaemia, unspecified
0.000 0.967 0.033
D58 Other hereditary haemolytic anaemias
0.001 0.970 0.029
D86.3 Sarcoidosis of skin
0.000 0.971 0.029
D59.8 Other acquired haemolytic anaemias
0.000 0.971 0.029
D59.6 Haemoglobinuria due to haemolysis from other external causes
0.000 0.971 0.029
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]
0.000 0.971 0.029
D59.4 Other nonautoimmune haemolytic anaemias
0.000 0.971 0.029
D59.3 Haemolytic-uraemic syndrome
0.000 0.971 0.029
D59.2 Drug-induced nonautoimmune haemolytic anaemia
0.000 0.971 0.029
R04.0 Epistaxis
0.029 0.971 0.000
D59.0 Drug-induced autoimmune haemolytic anaemia
0.000 0.972 0.028
J93.9 Pneumothorax, unspecified
0.000 0.972 0.028
D59.9 Acquired haemolytic anaemia, unspecified
0.000 0.973 0.026
D63.8 Anaemia in other chronic diseases classified elsewhere
0.000 0.974 0.026
D59.1 Other autoimmune haemolytic anaemias
0.000 0.974 0.025
R04 Haemorrhage from respiratory passages
0.024 0.976 0.000
R04.2 Haemoptysis
0.024 0.976 0.000
D58.8 Other specified hereditary haemolytic anaemias
0.001 0.978 0.021
D58.1 Hereditary elliptocytosis
0.001 0.978 0.021
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.978 0.021
K90-K93 Other diseases of the digestive system
0.000 0.979 0.021
D86.0 Sarcoidosis of lung
0.000 0.980 0.020
D58.2 Other haemoglobinopathies
0.001 0.980 0.019
R04.1 Haemorrhage from throat
0.019 0.981 0.000
D58.9 Hereditary haemolytic anaemia, unspecified
0.001 0.982 0.018
R04.9 Haemorrhage from respiratory passages, unspecified
0.018 0.982 0.000
R04.8 Haemorrhage from other sites in respiratory passages
0.018 0.982 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.000 0.983 0.017
E83.3 Disorders of phosphorus metabolism
0.015 0.983 0.002
D74 Methaemoglobinaemia
0.000 0.984 0.016
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.000 0.984 0.016
D71 Functional disorders of polymorphonuclear neutrophils
0.000 0.984 0.016
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.985 0.015
D86.9 Sarcoidosis, unspecified
0.000 0.985 0.015
D58.0 Hereditary spherocytosis
0.001 0.985 0.014
D76.3 Other histiocytosis syndromes
0.000 0.986 0.014
E89.0 Postprocedural hypothyroidism
0.014 0.986 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.013 0.987 0.000
D73 Diseases of spleen
0.000 0.987 0.013
S92.30 Fracture of metatarsal bone (closed)
0.000 0.987 0.013
E89.2 Postprocedural hypoparathyroidism
0.013 0.987 0.000
L20-L30 Dermatitis and eczema
0.000 0.987 0.013
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.987 0.012
D76.2 Haemophagocytic syndrome, infection-associated
0.000 0.988 0.012
D76.1 Haemophagocytic lymphohistiocytosis
0.000 0.988 0.012
D76.0 Langerhans' cell histiocytosis, not elsewhere classified
0.000 0.988 0.012
H54.7 Unspecified visual loss
0.000 0.988 0.012
D74.9 Methaemoglobinaemia, unspecified
0.000 0.988 0.011
D74.8 Other methaemoglobinaemias
0.000 0.988 0.011
D74.0 Congenital methaemoglobinaemia
0.000 0.988 0.011
E89.1 Postprocedural hypoinsulinaemia
0.011 0.988 0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.989 0.011
K93.1 Megacolon in Chagas' disease
0.000 0.989 0.011
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.989 0.011
E70-E90 Metabolic disorders
0.010 0.989 0.001
L21 Seborrhoeic dermatitis
0.000 0.989 0.011
J93 Pneumothorax
0.000 0.989 0.011
D37-D48 Neoplasms of uncertain or unknown behaviour
0.011 0.989 0.000
D46 Myelodysplastic syndromes
0.011 0.989 0.000
D73.3 Abscess of spleen
0.000 0.989 0.011
D72 Other disorders of white blood cells
0.000 0.989 0.010
D73.5 Infarction of spleen
0.000 0.989 0.010
D73.0 Hyposplenism
0.000 0.990 0.010
E85 Amyloidosis
0.010 0.990 0.000
L25 Unspecified contact dermatitis
0.000 0.990 0.010
L21.9 Seborrhoeic dermatitis, unspecified
0.000 0.990 0.010
D46.1 Refractory anaemia with sideroblasts
0.010 0.990 0.000
D46.2 Refractory anaemia with excess of blasts
0.010 0.990 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.009 0.990 0.000
E89.8 Other postprocedural endocrine and metabolic disorders
0.009 0.990 0.000
E89.5 Postprocedural testicular hypofunction
0.009 0.990 0.000
E78.5 Hyperlipidaemia, unspecified
0.000 0.990 0.010
D73.2 Chronic congestive splenomegaly
0.000 0.990 0.009
E85.4 Organ-limited amyloidosis
0.009 0.991 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.009 0.991 0.000
E89.4 Postprocedural ovarian failure
0.009 0.991 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.009 0.991 0.001
L24 Irritant contact dermatitis
0.000 0.991 0.009
L26 Exfoliative dermatitis
0.000 0.991 0.009
L22 Diaper [napkin] dermatitis
0.000 0.991 0.009
L20 Atopic dermatitis
0.000 0.991 0.009
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.009 0.991 0.000
E80.1 Porphyria cutanea tarda
0.009 0.991 0.000
E79 Disorders of purine and pyrimidine metabolism
0.008 0.991 0.001
L23 Allergic contact dermatitis
0.000 0.991 0.009
D39.0 Uterus
0.009 0.991 0.000
E85.9 Amyloidosis, unspecified
0.008 0.991 0.000
L25.9 Unspecified contact dermatitis, unspecified cause
0.000 0.991 0.009
D46.9 Myelodysplastic syndrome, unspecified
0.009 0.991 0.000
J93.1 Other spontaneous pneumothorax
0.000 0.991 0.008
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.008 0.991 0.000
D46.5 Refractory anaemia with multi-lineage dysplasia
0.008 0.992 0.000
E72 Other disorders of amino-acid metabolism
0.008 0.992 0.001
D67 Hereditary factor IX deficiency
0.000 0.992 0.008
E84 Cystic fibrosis
0.008 0.992 0.001
E77 Disorders of glycoprotein metabolism
0.008 0.992 0.001
E76 Disorders of glycosaminoglycan metabolism
0.008 0.992 0.001
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.008 0.992 0.001
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.008 0.992 0.001
D73.9 Disease of spleen, unspecified
0.000 0.992 0.008
E70 Disorders of aromatic amino-acid metabolism
0.007 0.992 0.001
L21.8 Other seborrhoeic dermatitis
0.000 0.992 0.008
L21.1 Seborrhoeic infantile dermatitis
0.000 0.992 0.008
L21.0 Seborrhoea capitis
0.000 0.992 0.008
D73.4 Cyst of spleen
0.000 0.992 0.008
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.008 0.992 0.000
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality
0.008 0.992 0.000
D46.3 Refractory anaemia with excess of blasts with transformation
0.008 0.992 0.000
D46.0 Refractory anaemia without sideroblasts, so stated
0.008 0.992 0.000
D73.1 Hypersplenism
0.000 0.992 0.008
E85.8 Other amyloidosis
0.008 0.992 0.000
E80.2 Other porphyria
0.008 0.992 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.008 0.992 0.000
D72.9 Disorder of white blood cells, unspecified
0.000 0.992 0.008
D72.0 Genetic anomalies of leukocytes
0.000 0.992 0.008
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.007 0.992 0.001
J93.0 Spontaneous tension pneumothorax
0.000 0.992 0.008
D46.7 Other myelodysplastic syndromes
0.008 0.992 0.000
D46.4 Refractory anaemia, unspecified
0.008 0.992 0.000
E85.2 Heredofamilial amyloidosis, unspecified
0.007 0.992 0.000
E85.1 Neuropathic heredofamilial amyloidosis
0.007 0.992 0.000
E85.0 Nonneuropathic heredofamilial amyloidosis
0.007 0.992 0.000
L25.8 Unspecified contact dermatitis due to other agents
0.000 0.992 0.007
L25.5 Unspecified contact dermatitis due to plants, except food
0.000 0.992 0.007
L25.4 Unspecified contact dermatitis due to food in contact with the skin
0.000 0.992 0.007
L25.3 Unspecified contact dermatitis due to other chemical products
0.000 0.992 0.007
L25.2 Unspecified contact dermatitis due to dyes
0.000 0.992 0.007
L25.1 Unspecified contact dermatitis due to drugs in contact with the skin
0.000 0.992 0.007
L25.0 Unspecified contact dermatitis due to cosmetics
0.000 0.992 0.007
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.000 0.992 0.007
J93.8 Other pneumothorax
0.000 0.992 0.007
D75 Other diseases of blood and blood-forming organs
0.000 0.993 0.007
D39.1 Ovary
0.007 0.993 0.000
L20.9 Atopic dermatitis, unspecified
0.000 0.993 0.007
E85.3 Secondary systemic amyloidosis
0.007 0.993 0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.007 0.993 0.000
D39.9 Female genital organ, unspecified
0.007 0.993 0.000
D39.2 Placenta
0.007 0.993 0.000
E80.7 Disorder of bilirubin metabolism, unspecified
0.006 0.993 0.001
E80.5 Crigler-Najjar syndrome
0.006 0.993 0.001
E80.3 Defects of catalase and peroxydase
0.006 0.993 0.001
E80.0 Hereditary erythropoietic porphyria
0.006 0.993 0.001
E83.4 Disorders of magnesium metabolism
0.005 0.993 0.002
E80.6 Other disorders of bilirubin metabolism
0.006 0.993 0.001
C18.6 Descending colon
0.000 0.993 0.007
L24.9 Irritant contact dermatitis, unspecified cause
0.000 0.993 0.007
L24.8 Irritant contact dermatitis due to other agents
0.000 0.993 0.007
L24.7 Irritant contact dermatitis due to plants, except food
0.000 0.993 0.007
L24.6 Irritant contact dermatitis due to food in contact with the skin
0.000 0.993 0.007
L24.5 Irritant contact dermatitis due to other chemical products
0.000 0.993 0.007
L24.4 Irritant contact dermatitis due to drugs in contact with the skin
0.000 0.993 0.007
L24.3 Irritant contact dermatitis due to cosmetics
0.000 0.993 0.007
L24.2 Irritant contact dermatitis due to solvents
0.000 0.993 0.007
L24.1 Irritant contact dermatitis due to oils and greases
0.000 0.993 0.007
L24.0 Irritant contact dermatitis due to detergents
0.000 0.993 0.007
L20.0 Besnier's prurigo
0.000 0.993 0.007
R14 Flatulence and related conditions
0.000 0.993 0.007
D38.0 Larynx
0.007 0.993 0.000
D38.1 Trachea, bronchus and lung
0.007 0.993 0.000
D73.8 Other diseases of spleen
0.000 0.993 0.006
L23.5 Allergic contact dermatitis due to other chemical products
0.000 0.993 0.007
E74 Other disorders of carbohydrate metabolism
0.006 0.993 0.001
D75.0 Familial erythrocytosis
0.000 0.993 0.007
S92.3 Fracture of metatarsal bone
0.000 0.993 0.007
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.007 0.993 0.000
L23.9 Allergic contact dermatitis, unspecified cause
0.000 0.993 0.006
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.006 0.993 0.001
E79.8 Other disorders of purine and pyrimidine metabolism
0.006 0.993 0.001
E79.1 Lesch-Nyhan syndrome
0.006 0.993 0.001
L23.7 Allergic contact dermatitis due to plants, except food
0.000 0.993 0.006
L23.6 Allergic contact dermatitis due to food in contact with the skin
0.000 0.993 0.006
L23.4 Allergic contact dermatitis due to dyes
0.000 0.993 0.006
L23.3 Allergic contact dermatitis due to drugs in contact with the skin
0.000 0.993 0.006
L23.2 Allergic contact dermatitis due to cosmetics
0.000 0.993 0.006
L23.0 Allergic contact dermatitis due to metals
0.000 0.993 0.006
L28 Lichen simplex chronicus and prurigo
0.000 0.993 0.006
L20.8 Other atopic dermatitis
0.000 0.993 0.006
E89.3 Postprocedural hypopituitarism
0.006 0.993 0.000
E73 Lactose intolerance
0.005 0.993 0.001
E88 Other metabolic disorders
0.006 0.993 0.001
D38.6 Respiratory organ, unspecified
0.006 0.994 0.000
D38.4 Thymus
0.006 0.994 0.000
D38.3 Mediastinum
0.006 0.994 0.000
D38.2 Pleura
0.006 0.994 0.000
E71.3 Disorders of fatty-acid metabolism
0.006 0.994 0.001
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.006 0.994 0.001
E71.1 Other disorders of branched-chain amino-acid metabolism
0.006 0.994 0.001
E71.0 Maple-syrup-urine disease
0.006 0.994 0.001
E72.9 Disorder of amino-acid metabolism, unspecified
0.006 0.994 0.001
E72.8 Other specified disorders of amino-acid metabolism
0.006 0.994 0.001
E72.5 Disorders of glycine metabolism
0.006 0.994 0.001
E72.4 Disorders of ornithine metabolism
0.006 0.994 0.001
E72.3 Disorders of lysine and hydroxylysine metabolism
0.006 0.994 0.001
E72.2 Disorders of urea cycle metabolism
0.006 0.994 0.001
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.006 0.994 0.001
E72.0 Disorders of amino-acid transport
0.006 0.994 0.001
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.006 0.994 0.001
E76.8 Other disorders of glucosaminoglycan metabolism
0.006 0.994 0.001
E76.3 Mucopolysaccharidosis, unspecified
0.006 0.994 0.001
E76.2 Other mucopolysaccharidoses
0.006 0.994 0.001
E76.1 Mucopolysaccharidosis, type II
0.006 0.994 0.001
E76.0 Mucopolysaccharidosis, type I
0.006 0.994 0.001
E77.9 Disorder of glycoprotein metabolism, unspecified
0.006 0.994 0.001
E77.8 Other disorders of glycoprotein metabolism
0.006 0.994 0.001
E77.1 Defects in glycoprotein degradation
0.006 0.994 0.001
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.006 0.994 0.001
E84.9 Cystic fibrosis, unspecified
0.006 0.994 0.001
E84.8 Cystic fibrosis with other manifestations
0.006 0.994 0.001
E84.1 Cystic fibrosis with intestinal manifestations
0.006 0.994 0.001
E84.0 Cystic fibrosis with pulmonary manifestations
0.006 0.994 0.001
D39.7 Other female genital organs
0.006 0.994 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.006 0.994 0.000
L23.1 Allergic contact dermatitis due to adhesives
0.000 0.994 0.006
D40.7 Other male genital organs
0.006 0.994 0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.006 0.994 0.001
E70.8 Other disorders of aromatic amino-acid metabolism
0.006 0.994 0.001
E70.2 Disorders of tyrosine metabolism
0.006 0.994 0.001
E70.1 Other hyperphenylalaninaemias
0.006 0.994 0.001
E70.0 Classical phenylketonuria
0.006 0.994 0.001
D40.0 Prostate
0.006 0.994 0.000
D42.9 Meninges, unspecified
0.006 0.994 0.000
D42.1 Spinal meninges
0.006 0.994 0.000
D42.0 Cerebral meninges
0.006 0.994 0.000
D44.6 Carotid body
0.006 0.994 0.000
E70.3 Albinism
0.005 0.994 0.001
D72.1 Eosinophilia
0.000 0.994 0.006
D40.9 Male genital organ, unspecified
0.006 0.994 0.000
L23.8 Allergic contact dermatitis due to other agents
0.000 0.994 0.006
E75.6 Lipid storage disorder, unspecified
0.005 0.994 0.001
E75.4 Neuronal ceroid lipofuscinosis
0.005 0.994 0.001
E75.3 Sphingolipidosis, unspecified
0.005 0.994 0.001
E75.1 Other gangliosidosis
0.005 0.994 0.001
E75.0 GM2 gangliosidosis
0.005 0.994 0.001
E75.2 Other sphingolipidosis
0.005 0.994 0.001
D38.5 Other respiratory organs
0.006 0.994 0.000
D70 Agranulocytosis
0.000 0.994 0.006
D72.8 Other specified disorders of white blood cells
0.000 0.994 0.006
D66 Hereditary factor VIII deficiency
0.001 0.994 0.005
D75.8 Other specified diseases of blood and blood-forming organs
0.000 0.995 0.005
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.995 0.005
E88.1 Lipodystrophy, not elsewhere classified
0.005 0.995 0.000
E75.5 Other lipid storage disorders
0.005 0.995 0.001
E88.9 Metabolic disorder, unspecified
0.005 0.995 0.001
E88.8 Other specified metabolic disorders
0.005 0.995 0.001
E78.1 Pure hyperglyceridaemia
0.000 0.995 0.005
E74.9 Disorder of carbohydrate metabolism, unspecified
0.004 0.995 0.001
E74.8 Other specified disorders of carbohydrate metabolism
0.004 0.995 0.001
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.004 0.995 0.001
E74.2 Disorders of galactose metabolism
0.004 0.995 0.001
E74.1 Disorders of fructose metabolism
0.004 0.995 0.001
E74.0 Glycogen storage disease
0.004 0.995 0.001
V23.4 Driver injured in traffic accident
0.000 0.995 0.005
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.005 0.995 0.000
S92.31 Fracture of metatarsal bone (open)
0.000 0.995 0.005
E78.6 Lipoprotein deficiency
0.000 0.995 0.005
D40.1 Testis
0.005 0.995 0.000
L28.2 Other prurigo
0.000 0.995 0.005
E73.8 Other lactose intolerance
0.004 0.995 0.001
E73.1 Secondary lactase deficiency
0.004 0.995 0.001
E73.0 Congenital lactase deficiency
0.004 0.995 0.001
L28.1 Prurigo nodularis
0.000 0.995 0.005
L29 Pruritus
0.000 0.995 0.005
D44.9 Endocrine gland, unspecified
0.005 0.995 0.000
D44.5 Pineal gland
0.005 0.995 0.000
D44.2 Parathyroid gland
0.005 0.995 0.000
A08.4 Viral intestinal infection, unspecified
0.005 0.995 0.000
D44.0 Thyroid gland
0.004 0.995 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.995 0.005
E88.3 Tumour lysis syndrome
0.004 0.995 0.001
D69 Purpura and other haemorrhagic conditions
0.000 0.995 0.004
K72.0 Acute and subacute hepatic failure
0.000 0.995 0.005
L29.2 Pruritus vulvae
0.000 0.995 0.004
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.004 0.995 0.000
L30 Other dermatitis
0.000 0.995 0.004
G61.0 Guillain-Barre syndrome
0.000 0.996 0.004
E78.2 Mixed hyperlipidaemia
0.000 0.996 0.004
D48.4 Peritoneum
0.004 0.996 0.000
E78.4 Other hyperlipidaemia
0.000 0.996 0.004
F06.7 Mild cognitive disorder
0.004 0.996 0.000
D44.7 Aortic body and other paraganglia
0.004 0.996 0.000
K86.3 Pseudocyst of pancreas
0.000 0.996 0.004
D48.7 Other specified sites
0.004 0.996 0.000
E78.3 Hyperchylomicronaemia
0.000 0.996 0.004
D44.3 Pituitary gland
0.004 0.996 0.000
D44.4 Craniopharyngeal duct
0.004 0.996 0.000
E88.2 Lipomatosis, not elsewhere classified
0.003 0.996 0.001
E10.2 With renal complications
0.000 0.996 0.004
D69.0 Allergic purpura
0.000 0.996 0.004
Q66.3 Other congenital varus deformities of feet
0.004 0.996 0.000
D44.8 Pluriglandular involvement
0.004 0.996 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.000 0.996 0.004
D48.3 Retroperitoneum
0.004 0.996 0.000
C71.1 Frontal lobe
0.000 0.996 0.004
H54 Blindness and low vision
0.000 0.996 0.004
D48.1 Connective and other soft tissue
0.004 0.996 0.000
D48.6 Breast
0.004 0.996 0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems
0.000 0.996 0.004
S83.2 Tear of meniscus, current
0.000 0.996 0.004
Q24.8 Other specified congenital malformations of heart
0.004 0.996 0.000
K60.2 Anal fissure, unspecified
0.000 0.996 0.004
L29.1 Pruritus scroti
0.000 0.996 0.003
E74.3 Other disorders of intestinal carbohydrate absorption
0.002 0.996 0.001
Z37.0 Single live birth
0.004 0.996 0.000
D75.2 Essential thrombocytosis
0.001 0.996 0.003
D48.2 Peripheral nerves and autonomic nervous system
0.004 0.996 0.000
H54.0 Blindness, both eyes
0.000 0.996 0.004
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified
0.003 0.996 0.000
D69.2 Other nonthrombocytopenic purpura
0.000 0.996 0.003
H93.1 Tinnitus
0.004 0.996 0.000
K75.9 Inflammatory liver disease, unspecified
0.000 0.996 0.004
D69.1 Qualitative platelet defects
0.000 0.996 0.003
D43.9 Central nervous system, unspecified
0.003 0.996 0.000
D43.7 Other parts of central nervous system
0.003 0.996 0.000
D43.4 Spinal cord
0.003 0.996 0.000
D43.3 Cranial nerves
0.003 0.996 0.000
O26.9 Pregnancy-related condition, unspecified
0.004 0.996 0.000
L29.3 Anogenital pruritus, unspecified
0.000 0.996 0.003
D44.1 Adrenal gland
0.003 0.996 0.000
L30.5 Pityriasis alba
0.000 0.996 0.003
L30.2 Cutaneous autosensitisation
0.000 0.996 0.003
L30.0 Nummular dermatitis
0.000 0.996 0.003
O04.9 Complete or unspecified, without complication
0.004 0.996 0.000
L30.4 Erythema intertrigo
0.000 0.997 0.003
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.997 0.003
D75.9 Disease of blood and blood-forming organs, unspecified
0.001 0.997 0.003
E10.1 With ketoacidosis
0.000 0.997 0.003
L30.1 Dyshidrosis [pompholyx]
0.000 0.997 0.003
L29.8 Other pruritus
0.000 0.997 0.003
V23 Motorcycle rider injured in collision with car, pick-up truck or van
0.000 0.997 0.003
L30.3 Infective dermatitis
0.000 0.997 0.003
D69.9 Haemorrhagic condition, unspecified
0.000 0.997 0.003
C18.9 Colon, unspecified
0.000 0.997 0.003
D43.0 Brain, supratentorial
0.003 0.997 0.000
D69.8 Other specified haemorrhagic conditions
0.000 0.997 0.003
E73.9 Lactose intolerance, unspecified
0.002 0.997 0.002
H53.2 Diplopia
0.003 0.997 0.000
H00.1 Chalazion
0.003 0.997 0.000
K75.4 Autoimmune hepatitis
0.000 0.997 0.003
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.003 0.997 0.000
D68.9 Coagulation defect, unspecified
0.000 0.997 0.003
E83.5 Disorders of calcium metabolism
0.001 0.997 0.002
Y60.4 During endoscopic examination
0.000 0.997 0.003
H54.6 Unqualified visual loss, one eye
0.000 0.997 0.003
E10.3 With ophthalmic complications
0.000 0.997 0.003
H54.2 Low vision, both eyes
0.000 0.997 0.003
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.003 0.997 0.000
H54.1 Blindness, one eye, low vision, other eye
0.000 0.997 0.003
H93 Other disorders of ear, not elsewhere classified
0.003 0.997 0.000
D69.4 Other primary thrombocytopenia
0.000 0.997 0.003
Y60.0 During surgical operation
0.000 0.997 0.003
Q66 Congenital deformities of feet
0.003 0.997 0.000
H54.3 Unqualified visual loss, both eyes
0.000 0.997 0.003
S61.9 Open wound of wrist and hand, part unspecified
0.003 0.997 0.000
E06.3 Autoimmune thyroiditis
0.000 0.997 0.003

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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