TreeWAS – Variant ID: rs12245680

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E11.9 Without complications	1.000	0.000	0.000
E11 Non-insulin-dependent diabetes mellitus	0.987	0.013	0.000
E11.3 With ophthalmic complications	0.967	0.033	0.000
E11.2 With renal complications	0.838	0.162	0.000
E11.6 With other specified complications	0.802	0.198	0.000
E10-E14 Diabetes mellitus	0.781	0.219	0.000
E11.1 With ketoacidosis	0.748	0.252	0.000
E14 Unspecified diabetes mellitus	0.736	0.264	0.000
E11.7 With multiple complications	0.707	0.293	0.000
E11.8 With unspecified complications	0.689	0.311	0.000
E14.9 Without complications	0.660	0.340	0.000
E11.5 With peripheral circulatory complications	0.647	0.353	0.000
E11.4 With neurological complications	0.635	0.365	0.000
E14.4 With neurological complications	0.618	0.382	0.000
E11.0 With coma	0.612	0.388	0.000
E10 Insulin-dependent diabetes mellitus	0.581	0.419	0.000
E10.9 Without complications	0.571	0.429	0.000
E12 Malnutrition-related diabetes mellitus	0.560	0.440	0.000
E13 Other specified diabetes mellitus	0.556	0.444	0.000
E14.1 With ketoacidosis	0.552	0.448	0.000
E14.8 With unspecified complications	0.548	0.452	0.000
E14.3 With ophthalmic complications	0.538	0.462	0.000
E14.7 With multiple complications	0.527	0.472	0.000
E14.6 With other specified complications	0.527	0.472	0.000
E14.5 With peripheral circulatory complications	0.527	0.472	0.000
E14.2 Withrenal complications	0.527	0.472	0.000
E14.0 With coma	0.527	0.472	0.000
E10.5 With peripheral circulatory complications	0.434	0.566	0.000
E10.7 With multiple complications	0.417	0.583	0.000
E10.0 With coma	0.417	0.583	0.000
E10.8 With unspecified complications	0.413	0.587	0.000
E12.9 Without complications	0.402	0.598	0.000
E12.8 With unspecified complications	0.402	0.598	0.000
E12.7 With multiple complications	0.402	0.598	0.000
E12.6 With other specified complications	0.402	0.598	0.000
E12.5 With peripheral circulatory complications	0.402	0.598	0.000
E12.4 With neurological complications	0.402	0.598	0.000
E12.3 With ophthalmic complications	0.402	0.598	0.000
E12.2 With renal complications	0.402	0.598	0.000
E12.1 With ketoacidosis	0.402	0.598	0.000
E12.0 With coma	0.402	0.598	0.000
E13.8 With unspecified complications	0.398	0.601	0.000
E13.7 With multiple complications	0.398	0.601	0.000
E13.6 With other specified complications	0.398	0.601	0.000
E13.5 With peripheral circulatory complications	0.398	0.601	0.000
E13.4 With neurological complications	0.398	0.601	0.000
E13.3 With ophthalmic complications	0.398	0.601	0.000
E13.2 With renal complications	0.398	0.601	0.000
E13.1 With ketoacidosis	0.398	0.601	0.000
E13.0 With coma	0.398	0.601	0.000
E13.9 Without complications	0.394	0.606	0.000
E10.2 With renal complications	0.392	0.608	0.000
E10.6 With other specified complications	0.384	0.615	0.000
E10.3 With ophthalmic complications	0.265	0.735	0.000
E10.4 With neurological complications	0.207	0.792	0.001
E10.1 With ketoacidosis	0.206	0.793	0.001
C79.8 Secondary malignant neoplasm of other specified sites	0.000	0.983	0.017
C79 Secondary malignant neoplasm of other sites	0.000	0.984	0.016
C79.6 Secondary malignant neoplasm of ovary	0.000	0.985	0.015
C79.2 Secondary malignant neoplasm of skin	0.000	0.986	0.014
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.000	0.986	0.014
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.000	0.986	0.013
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.000	0.987	0.013
E21.0 Primary hyperparathyroidism	0.000	0.989	0.011
E20-E35 Disorders of other endocrine glands	0.001	0.989	0.011
Chapter IV Endocrine, nutritional and metabolic diseases	0.007	0.989	0.004
E23 Hypofunction and other disorders of pituitary gland	0.000	0.989	0.011
C79.9 Secondary malignant neoplasm, unspecified site	0.000	0.989	0.011
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.989	0.010
E23.2 Diabetes insipidus	0.000	0.989	0.011
E27 Other disorders of adrenal gland	0.000	0.990	0.010
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.000	0.990	0.010
K81.0 Acute cholecystitis	0.010	0.990	0.000
E24 Cushing's syndrome	0.000	0.990	0.009
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.000	0.990	0.010
R09.0 Asphyxia	0.000	0.990	0.010
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.990	0.009
E23.0 Hypopituitarism	0.000	0.990	0.009
E27.1 Primary adrenocortical insufficiency	0.000	0.991	0.009
R09.1 Pleurisy	0.000	0.991	0.009
C79.7 Secondary malignant neoplasm of adrenal gland	0.000	0.991	0.009
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems	0.000	0.991	0.009
E24.9 Cushing's syndrome, unspecified	0.000	0.991	0.009
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.000	0.991	0.009
E26 Hyperaldosteronism	0.000	0.992	0.008
E21.3 Hyperparathyroidism, unspecified	0.000	0.992	0.008
E29 Testicular dysfunction	0.000	0.992	0.008
E28 Ovarian dysfunction	0.000	0.992	0.008
E35 Disorders of endocrine glands in diseases classified elsewhere	0.001	0.992	0.008
E32 Diseases of thymus	0.001	0.992	0.008
E31 Polyglandular dysfunction	0.001	0.992	0.008
E30 Disorders of puberty, not elsewhere classified	0.001	0.992	0.008
E25 Adrenogenital disorders	0.001	0.992	0.008
R09.3 Abnormal sputum	0.000	0.992	0.008
R09.2 Respiratory arrest	0.000	0.992	0.008
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.992	0.008
E23.1 Drug-induced hypopituitarism	0.000	0.992	0.008
E34 Other endocrine disorders	0.001	0.992	0.007
E23.7 Disorder of pituitary gland, unspecified	0.000	0.992	0.008
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.992	0.008
E21.4 Other specified disorders of parathyroid gland	0.000	0.992	0.008
E21.2 Other hyperparathyroidism	0.000	0.992	0.008
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.005	0.992	0.002
E23.6 Other disorders of pituitary gland	0.000	0.992	0.007
E27.2 Addisonian crisis	0.000	0.992	0.007
E40-E46 Malnutrition	0.004	0.992	0.004
E27.5 Adrenomedullary hyperfunction	0.000	0.992	0.007
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.992	0.007
E27.0 Other adrenocortical overactivity	0.000	0.992	0.007
E24.8 Other Cushing's syndrome	0.000	0.993	0.007
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.993	0.007
E24.3 Ectopic ACTH syndrome	0.000	0.993	0.007
E24.2 Drug-induced Cushing's syndrome	0.000	0.993	0.007
E24.1 Nelson's syndrome	0.000	0.993	0.007
E24.0 Pituitary-dependent Cushing's disease	0.000	0.993	0.007
E20 Hypoparathyroidism	0.001	0.993	0.007
E27.8 Other specified disorders of adrenal gland	0.000	0.993	0.007
E50-E64 Other nutritional deficiencies	0.005	0.993	0.002
E04.2 Non-toxic multinodular goitre	0.000	0.993	0.007
E04 Other non-toxic goitre	0.000	0.993	0.007
E28.2 Polycystic ovarian syndrome	0.000	0.993	0.007
E34.9 Endocrine disorder, unspecified	0.000	0.993	0.006
E26.0 Primary hyperaldosteronism	0.000	0.993	0.006
E27.9 Disorder of adrenal gland, unspecified	0.000	0.993	0.006
E29.1 Testicular hypofunction	0.000	0.994	0.006
E26.9 Hyperaldosteronism, unspecified	0.001	0.994	0.006
E26.8 Other hyperaldosteronism	0.001	0.994	0.006
E26.1 Secondary hyperaldosteronism	0.001	0.994	0.006
E00-E07 Disorders of thyroid gland	0.001	0.994	0.005
E04.9 Non-toxic goitre, unspecified	0.000	0.994	0.006
E29.9 Testicular dysfunction, unspecified	0.000	0.994	0.006
E29.8 Other testicular dysfunction	0.000	0.994	0.006
E29.0 Testicular hyperfunction	0.000	0.994	0.006
Z50.8 Care involving use of rehabilitation procedures	0.000	0.994	0.006
E28.9 Ovarian dysfunction, unspecified	0.000	0.994	0.006
E28.8 Other ovarian dysfunction	0.000	0.994	0.006
E28.1 Androgen excess	0.000	0.994	0.006
E28.0 Oestrogen excess	0.000	0.994	0.006
M54.99 Dorsalgia, unspecified (Site unspecified)	0.000	0.994	0.006
E25.9 Adrenogenital disorder, unspecified	0.001	0.994	0.006
E25.8 Other adrenogenital disorders	0.001	0.994	0.006
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.001	0.994	0.006
E30.9 Disorder of puberty, unspecified	0.001	0.994	0.006
E30.8 Other disorders of puberty	0.001	0.994	0.006
E30.1 Precocious puberty	0.001	0.994	0.006
E30.0 Delayed puberty	0.001	0.994	0.006
E31.9 Polyglandular dysfunction, unspecified	0.001	0.994	0.006
E31.8 Other polyglandular dysfunction	0.001	0.994	0.006
E31.1 Polyglandular hyperfunction	0.001	0.994	0.006
E31.0 Autoimmune polyglandular failure	0.001	0.994	0.006
E32.9 Disease of thymus, unspecified	0.001	0.994	0.006
E32.8 Other diseases of thymus	0.001	0.994	0.006
E32.1 Abscess of thymus	0.001	0.994	0.006
E32.0 Persistent hyperplasia of thymus	0.001	0.994	0.006
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.001	0.994	0.006
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.001	0.994	0.006
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.001	0.994	0.006
C34.9 Bronchus or lung, unspecified	0.000	0.994	0.006
E34.5 Androgen resistance syndrome	0.001	0.994	0.006
E34.4 Constitutional tall stature	0.001	0.994	0.006
E34.3 Short stature, not elsewhere classified	0.001	0.994	0.006
E34.2 Ectopic hormone secretion, not elsewhere classified	0.001	0.994	0.006
E34.1 Other hypersecretion of intestinal hormones	0.001	0.994	0.006
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.001	0.994	0.005
E34.8 Other specified endocrine disorders	0.001	0.994	0.005
R56.8 Other and unspecified convulsions	0.000	0.994	0.006
E04.1 Non-toxic single thyroid nodule	0.000	0.994	0.006
E15 Nondiabetic hypoglycaemic coma	0.004	0.994	0.002
E04.0 Non-toxic diffuse goitre	0.000	0.994	0.006
S02.20 Fracture of nasal bones (closed)	0.006	0.994	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.003	0.994	0.003
E45 Retarded development following protein-energy malnutrition	0.003	0.994	0.003
E43 Unspecified severe protein-energy malnutrition	0.003	0.994	0.003
E42 Marasmic kwashiorkor	0.003	0.994	0.003
E41 Nutritional marasmus	0.003	0.994	0.003
E40 Kwashiorkor	0.003	0.994	0.003
E22 Hyperfunction of pituitary gland	0.001	0.994	0.005
E28.3 Primary ovarian failure	0.001	0.994	0.005
E06 Thyroiditis	0.001	0.994	0.005
E16 Other disorders of pancreatic internal secretion	0.005	0.994	0.001
E53 Deficiency of other B group vitamins	0.005	0.995	0.001
E46 Unspecified protein-energy malnutrition	0.001	0.995	0.004
E20.8 Other hypoparathyroidism	0.001	0.995	0.005
E20.1 Pseudohypoparathyroidism	0.001	0.995	0.005
E20.0 Idiopathic hypoparathyroidism	0.001	0.995	0.005
E64 Sequelae of malnutrition and other nutritional deficiencies	0.004	0.995	0.001
E63 Other nutritional deficiencies	0.004	0.995	0.001
E56 Other vitamin deficiencies	0.004	0.995	0.001
E51 Thiamine deficiency	0.004	0.995	0.001
E50 Vitamin A deficiency	0.004	0.995	0.001
E60 Dietary zinc deficiency	0.004	0.995	0.001
E59 Dietary selenium deficiency	0.004	0.995	0.001
E58 Dietary calcium deficiency	0.004	0.995	0.001
E54 Ascorbic acid deficiency	0.004	0.995	0.001
E52 Niacin deficiency [pellagra]	0.004	0.995	0.001
E04.8 Other specified non-toxic goitre	0.000	0.995	0.005
E61 Deficiency of other nutrient elements	0.004	0.995	0.001
E65-E68 Obesity and other hyperalimentation	0.002	0.995	0.003
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.995	0.005
H36.0 Diabetic retinopathy	0.005	0.995	0.000
E06.3 Autoimmune thyroiditis	0.000	0.995	0.005
E34.0 Carcinoid syndrome	0.001	0.995	0.004
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.001	0.995	0.004
E00 Congenital iodine-deficiency syndrome	0.001	0.995	0.004
E55 Vitamin D deficiency	0.004	0.995	0.001
M35.3 Polymyalgia rheumatica	0.000	0.995	0.005
E06.9 Thyroiditis, unspecified	0.000	0.995	0.004
E16.1 Other hypoglycaemia	0.004	0.996	0.001
E20.9 Hypoparathyroidism, unspecified	0.001	0.996	0.004
E44.1 Mild protein-energy malnutrition	0.002	0.996	0.002
E44.0 Moderate protein-energy malnutrition	0.002	0.996	0.002
M11.26 Other chondrocalcinosis (Lower leg)	0.004	0.996	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.996	0.004
E53.8 Deficiency of other specified B group vitamins	0.004	0.996	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.001	0.996	0.004
E22.8 Other hyperfunction of pituitary gland	0.001	0.996	0.004
D03.5 Melanoma in situ of trunk	0.004	0.996	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.996	0.004
E06.5 Other chronic thyroiditis	0.001	0.996	0.004
E06.4 Drug-induced thyroiditis	0.001	0.996	0.004
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.001	0.996	0.004
E06.1 Subacute thyroiditis	0.001	0.996	0.004
E06.0 Acute thyroiditis	0.001	0.996	0.004
E16.9 Disorder of pancreatic internal secretion, unspecified	0.003	0.996	0.001
E16.8 Other specified disorders of pancreatic internal secretion	0.003	0.996	0.001
E16.4 Abnormal secretion of gastrin	0.003	0.996	0.001
E16.3 Increased secretion of glucagon	0.003	0.996	0.001
E53.9 Vitamin B deficiency, unspecified	0.003	0.996	0.001
E53.1 Pyridoxine deficiency	0.003	0.996	0.001
E53.0 Riboflavin deficiency	0.003	0.996	0.001
E02 Subclinical iodine-deficiency hypothyroidism	0.001	0.996	0.003
E50.9 Vitamin A deficiency, unspecified	0.003	0.996	0.001
E50.8 Other manifestations of vitamin A deficiency	0.003	0.996	0.001
E50.7 Other ocular manifestations of vitamin A deficiency	0.003	0.996	0.001
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.003	0.996	0.001
E50.5 Vitamin A deficiency with night blindness	0.003	0.996	0.001
E50.4 Vitamin A deficiency with keratomalacia	0.003	0.996	0.001
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.003	0.996	0.001
E50.2 Vitamin A deficiency with corneal xerosis	0.003	0.996	0.001
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.003	0.996	0.001
E50.0 Vitamin A deficiency with conjunctival xerosis	0.003	0.996	0.001
E51.9 Thiamine deficiency, unspecified	0.003	0.996	0.001
E51.8 Other manifestations of thiamine deficiency	0.003	0.996	0.001
E51.2 Wernicke's encephalopathy	0.003	0.996	0.001
E51.1 Beriberi	0.003	0.996	0.001
E56.9 Vitamin deficiency, unspecified	0.003	0.996	0.001
E56.8 Deficiency of other vitamins	0.003	0.996	0.001
E56.1 Deficiency of vitamin K	0.003	0.996	0.001
E56.0 Deficiency of vitamin E	0.003	0.996	0.001
E63.9 Nutritional deficiency, unspecified	0.003	0.996	0.001
E63.8 Other specified nutritional deficiencies	0.003	0.996	0.001
E63.1 Imbalance of constituents of food intake	0.003	0.996	0.001
E63.0 Essential fatty acid [EFA] deficiency	0.003	0.996	0.001
E64.9 Sequelae of unspecified nutritional deficiency	0.003	0.996	0.001
E64.8 Sequelae of other nutritional deficiencies	0.003	0.996	0.001
E64.3 Sequelae of rickets	0.003	0.996	0.001
E64.2 Sequelae of vitamin C deficiency	0.003	0.996	0.001
E64.1 Sequelae of vitamin A deficiency	0.003	0.996	0.001
E64.0 Sequelae of protein-energy malnutrition	0.003	0.996	0.001
E22.1 Hyperprolactinaemia	0.001	0.996	0.003
E16.2 Hypoglycaemia, unspecified	0.004	0.996	0.000
E61.9 Deficiency of nutrient element, unspecified	0.003	0.996	0.001
E61.8 Deficiency of other specified nutrient elements	0.003	0.996	0.001
E61.7 Deficiency of multiple nutrient elements	0.003	0.996	0.001
E61.6 Vanadium deficiency	0.003	0.996	0.001
E61.5 Molybdenum deficiency	0.003	0.996	0.001
E61.4 Chromium deficiency	0.003	0.996	0.001
E61.3 Manganese deficiency	0.003	0.996	0.001
E61.2 Magnesium deficiency	0.003	0.996	0.001
E61.0 Copper deficiency	0.003	0.996	0.001
E16.0 Drug-induced hypoglycaemia without coma	0.003	0.996	0.001
E67 Other hyperalimentation	0.002	0.996	0.002
E68 Sequelae of hyperalimentation	0.002	0.996	0.002
E05.9 Thyrotoxicosis, unspecified	0.000	0.996	0.004
E07 Other disorders of thyroid	0.001	0.996	0.003
E05.5 Thyroid crisis or storm	0.000	0.996	0.004
E05.4 Thyrotoxicosis factitia	0.000	0.996	0.004
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.996	0.004
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.996	0.004
D03 Melanoma in situ	0.004	0.996	0.000
E05.8 Other thyrotoxicosis	0.000	0.996	0.004
E61.1 Iron deficiency	0.003	0.996	0.001
E65 Localised adiposity	0.001	0.996	0.003
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.001	0.996	0.003
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.001	0.996	0.003
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.001	0.996	0.003
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.001	0.996	0.003
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.001	0.996	0.003
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.001	0.996	0.003
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.001	0.996	0.003
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.001	0.996	0.003
D03.4 Melanoma in situ of scalp and neck	0.004	0.996	0.000
R32 Unspecified urinary incontinence	0.000	0.996	0.004
E55.0 Rickets, active	0.003	0.996	0.001
D03.7 Melanoma in situ of lower limb, including hip	0.004	0.996	0.000
Z09.2 Follow-up examination after chemotherapy for other conditions	0.000	0.996	0.004
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.001	0.996	0.003
D03.3 Melanoma in situ of other and unspecified parts of face	0.003	0.997	0.000
E22.0 Acromegaly and pituitary gigantism	0.001	0.997	0.003
M35 Other systemic involvement of connective tissue	0.000	0.997	0.003
M35.7 Hypermobility syndrome	0.000	0.997	0.003
S02.2 Fracture of nasal bones	0.003	0.997	0.000
D03.2 Melanoma in situ of ear and external auricular canal	0.003	0.997	0.000
E67.8 Other specified hyperalimentation	0.001	0.997	0.002
E67.3 Hypervitaminosis D	0.001	0.997	0.002
E67.2 Megavitamin-B6 syndrome	0.001	0.997	0.002
E67.1 Hypercarotenaemia	0.001	0.997	0.002
E67.0 Hypervitaminosis A	0.001	0.997	0.002
E07.1 Dyshormogenetic goitre	0.001	0.997	0.002
E07.0 Hypersecretion of calcitonin	0.001	0.997	0.002
M35.0 Sicca syndrome [Sjogren]	0.000	0.997	0.003
D03.9 Melanoma in situ, unspecified	0.003	0.997	0.000
D03.8 Melanoma in situ of other sites	0.003	0.997	0.000
D03.1 Melanoma in situ of eyelid, including canthus	0.003	0.997	0.000
D03.0 Melanoma in situ of lip	0.003	0.997	0.000
E07.8 Other specified disorders of thyroid	0.001	0.997	0.002
E55.9 Vitamin D deficiency, unspecified	0.002	0.997	0.001
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.000	0.997	0.003
M54.9 Dorsalgia, unspecified	0.000	0.997	0.003
M35.1 Other overlap syndromes	0.000	0.997	0.003
M35.9 Systemic involvement of connective tissue, unspecified	0.000	0.997	0.003
M35.8 Other specified systemic involvement of connective tissue	0.000	0.997	0.003
M35.6 Relapsing panniculitis [Weber-Christian]	0.000	0.997	0.003
M35.5 Multifocal fibrosclerosis	0.000	0.997	0.003
M35.4 Diffuse (eosinophilic) fasciitis	0.000	0.997	0.003
M35.2 Behcet's disease	0.000	0.997	0.003
S02.21 Fracture of nasal bones (open)	0.003	0.997	0.000
H21.8 Other specified disorders of iris and ciliary body	0.000	0.997	0.003
M11.2 Other chondrocalcinosis	0.003	0.997	0.000
Y42.7 Androgens and anabolic congeners	0.000	0.997	0.003
D03.6 Melanoma in situ of upper limb, including shoulder	0.003	0.997	0.000
H36 Retinal disorders in diseases classified elsewhere	0.003	0.997	0.000
R56 Convulsions, not elsewhere classified	0.000	0.997	0.003
I51.7 Cardiomegaly	0.000	0.997	0.003
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.000	0.997	0.002
M54.97 Dorsalgia, unspecified (Lumbosacral region)	0.000	0.998	0.002
J18.1 Lobar pneumonia, unspecified	0.000	0.998	0.002
O24.4 Diabetes mellitus arising in pregnancy	0.002	0.998	0.000
E03 Other hypothyroidism	0.001	0.998	0.002
M81.99 Osteoporosis, unspecified (Site unspecified)	0.000	0.998	0.002
S56.1 Injury of flexor muscle and tendon of other finger(s) at forearm level	0.002	0.998	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
M10.99 Gout, unspecified (Site unspecified)	0.000	0.998	0.002
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M54.93 Dorsalgia, unspecified (Cervicothoracic region)	0.000	0.998	0.002
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)	0.000	0.998	0.002
S52.10 Fracture of upper end of radius (closed)	0.002	0.998	0.000
O20.9 Haemorrhage in early pregnancy, unspecified	0.002	0.998	0.000
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified	0.000	0.998	0.002
M54.90 Dorsalgia, unspecified (Multiple sites in spine)	0.000	0.998	0.002
M54.94 Dorsalgia, unspecified (Thoracic region)	0.000	0.998	0.002
E07.9 Disorder of thyroid, unspecified	0.002	0.998	0.001
M80.9 Unspecified osteoporosis with pathological fracture	0.000	0.998	0.002
R10.0 Acute abdomen	0.002	0.998	0.000
M11.29 Other chondrocalcinosis (Site unspecified)	0.002	0.998	0.000
M11.28 Other chondrocalcinosis (Other)	0.002	0.998	0.000
M11.27 Other chondrocalcinosis (Ankle and foot)	0.002	0.998	0.000
M11.25 Other chondrocalcinosis (Pelvic region and thigh)	0.002	0.998	0.000
M11.24 Other chondrocalcinosis (Hand)	0.002	0.998	0.000
M11.23 Other chondrocalcinosis (Forearm)	0.002	0.998	0.000
M11.22 Other chondrocalcinosis (Upper arm)	0.002	0.998	0.000
M11.21 Other chondrocalcinosis (Shoulder region)	0.002	0.998	0.000
M11.20 Other chondrocalcinosis (Multiple sites)	0.002	0.998	0.000
M54.92 Dorsalgia, unspecified (Cervical region)	0.000	0.998	0.002
S51.9 Open wound of forearm, part unspecified	0.002	0.998	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.998	0.002
H36.8 Other retinal disorders in diseases classified elsewhere	0.002	0.998	0.000
R52.1 Chronic intractable pain	0.000	0.998	0.002
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.000	0.998	0.002
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.998	0.002
S56 Injury of muscle and tendon at forearm level	0.002	0.998	0.000
S52.20 Fracture of shaft of ulna (closed)	0.002	0.998	0.000
R56.0 Febrile convulsions	0.000	0.998	0.002
S51 Open wound of forearm	0.002	0.998	0.000
S52.1 Fracture of upper end of radius	0.002	0.998	0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)	0.000	0.998	0.002
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.998	0.002
E03.5 Myxoedema coma	0.001	0.998	0.001
E03.4 Atrophy of thyroid (acquired)	0.001	0.998	0.001
E03.3 Postinfectious hypothyroidism	0.001	0.998	0.001
E03.1 Congenital hypothyroidism without goitre	0.001	0.998	0.001
E03.0 Congenital hypothyroidism with diffuse goitre	0.001	0.998	0.001
S52.2 Fracture of shaft of ulna	0.002	0.998	0.000
S50-S59 Injuries to the elbow and forearm	0.002	0.998	0.000
N90.5 Atrophy of vulva	0.000	0.998	0.002
C34 Malignant neoplasm of bronchus and lung	0.000	0.998	0.002
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.001	0.998	0.001
S52 Fracture of forearm	0.002	0.998	0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.002
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.000	0.998	0.002
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.000	0.998	0.002
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.002
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.000	0.998	0.002
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.000	0.998	0.002
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.000	0.998	0.002
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.000	0.998	0.002
S64.3 Injury of digital nerve of thumb	0.000	0.998	0.002
H21 Other disorders of iris and ciliary body	0.000	0.998	0.002
S55 Injury of blood vessels at forearm level	0.002	0.998	0.000
S51.8 Open wound of other parts of forearm	0.002	0.998	0.000
S51.7 Multiple open wounds of forearm	0.002	0.998	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.000	0.998	0.002
O24 Diabetes mellitus in pregnancy	0.002	0.998	0.000
S55.0 Injury of ulnar artery at forearm level	0.002	0.998	0.000
Y42.9 Other and unspecified hormone antagonists	0.000	0.998	0.002
Y42.4 Oral contraceptives	0.000	0.998	0.002
Y42.2 Antithyroid drugs	0.000	0.998	0.002
Y42.1 Thyroid hormones and substitutes	0.000	0.998	0.002
S54 Injury of nerves at forearm level	0.002	0.998	0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.002	0.998	0.000
F43.2 Adjustment disorders	0.002	0.998	0.000
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
S56.8 Injury of other and unspecified muscles and tendons at forearm level	0.002	0.998	0.000
S56.2 Injury of other flexor muscle and tendon at forearm level	0.002	0.998	0.000
S56.7 Injury of multiple muscles and tendons at forearm level	0.002	0.998	0.000
S56.5 Injury of other extensor muscle and tendon at forearm level	0.002	0.998	0.000
S56.3 Injury of extensor or abductor muscles and tendons of thumb at forearm level	0.002	0.998	0.000
S56.0 Injury of flexor muscle and tendon of thumb at forearm level	0.002	0.998	0.000
I86.1 Scrotal varices	0.002	0.998	0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm	0.002	0.998	0.000
S52.11 Fracture of upper end of radius (open)	0.002	0.998	0.000
E03.8 Other specified hypothyroidism	0.001	0.998	0.001
S54.0 Injury of ulnar nerve at forearm level	0.002	0.998	0.000
Y42.5 Other oestrogens and progestogens	0.000	0.998	0.002
M81.40 Drug-induced osteoporosis (Multiple sites)	0.000	0.998	0.002
H20.8 Other iridocyclitis	0.000	0.998	0.002
S53.3 Traumatic rupture of ulnar collateral ligament	0.002	0.998	0.000
S56.4 Injury of extensor muscle and tendon of other finger(s) at forearm level	0.002	0.998	0.000
S59 Other and unspecified injuries of forearm	0.002	0.998	0.000
S02.60 Fracture of mandible (closed)	0.002	0.998	0.000
S52.21 Fracture of shaft of ulna (open)	0.002	0.998	0.000
S58 Traumatic amputation of forearm	0.002	0.998	0.000
S57 Crushing injury of forearm	0.002	0.998	0.000
M54.22 Cervicalgia (Cervical region)	0.000	0.998	0.002
M54.96 Dorsalgia, unspecified (Lumbar region)	0.000	0.998	0.002
O63.9 Long labour, unspecified	0.000	0.998	0.002
C34.8 Overlapping lesion of bronchus and lung	0.000	0.998	0.002
D07.4 Penis	0.002	0.998	0.000
H20.0 Acute and subacute iridocyclitis	0.000	0.998	0.002
K61.0 Anal abscess	0.000	0.998	0.002
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.000	0.998	0.002
C34.2 Middle lobe, bronchus or lung	0.000	0.998	0.002
K81.8 Other cholecystitis	0.002	0.998	0.000
O24.9 Diabetes mellitus in pregnancy, unspecified	0.002	0.998	0.000
S52.9 Fracture of forearm, part unspecified	0.001	0.998	0.000
S52.4 Fracture of shafts of both ulna and radius	0.002	0.998	0.000
S55.9 Injury of unspecified blood vessel at forearm level	0.001	0.998	0.000
S55.8 Injury of other blood vessels at forearm level	0.001	0.998	0.000
S55.7 Injury of multiple blood vessels at forearm level	0.001	0.998	0.000
S55.2 Injury of vein at forearm level	0.001	0.998	0.000
S55.1 Injury of radial artery at forearm level	0.001	0.998	0.000
H21.9 Disorder of iris and ciliary body, unspecified	0.000	0.998	0.001
H21.4 Pupillary membranes	0.000	0.998	0.001
H21.3 Cyst of iris, ciliary body and anterior chamber	0.000	0.998	0.001
H21.2 Degeneration of iris and ciliary body	0.000	0.998	0.001
H21.0 Hyphaema	0.000	0.998	0.001
S02.6 Fracture of mandible	0.002	0.998	0.000
M54.29 Cervicalgia-Site unspe	0.000	0.998	0.002
O24.3 Pre-existing diabetes mellitus, unspecified	0.001	0.998	0.000
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.001	0.998	0.000
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.001	0.998	0.000
S52.3 Fracture of shaft of radius	0.001	0.998	0.000
D09.1 Other and unspecified urinary organs	0.002	0.998	0.000
H21.1 Other vascular disorders of iris and ciliary body	0.000	0.998	0.001
S52.0 Fracture of upper end of ulna	0.002	0.998	0.000
S53.1 Dislocation of elbow, unspecified	0.001	0.998	0.000
S53.4 Sprain and strain of elbow	0.001	0.998	0.000
S53.2 Traumatic rupture of radial collateral ligament	0.001	0.998	0.000
S53.0 Dislocation of radial head	0.001	0.998	0.000
S54.2 Injury of radial nerve at forearm level	0.001	0.998	0.000
S54.9 Injury of unspecified nerve at forearm level	0.001	0.998	0.000
S54.8 Injury of other nerves at forearm level	0.001	0.998	0.000
S54.7 Injury of multiple nerves at forearm level	0.001	0.998	0.000
S54.3 Injury of cutaneous sensory nerve at forearm level	0.001	0.998	0.000
S54.1 Injury of median nerve at forearm level	0.001	0.998	0.000
M66.06 Rupture of popliteal cyst-Lower leg	0.002	0.998	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.001	0.998	0.000
C34.0 Main bronchus	0.000	0.998	0.001
K14.9 Disease of tongue, unspecified	0.000	0.998	0.002
M54.2 Cervicalgia	0.000	0.998	0.002
S52.7 Multiple fractures of forearm	0.001	0.998	0.000
S64.1 Injury of median nerve at wrist and hand level	0.000	0.998	0.002
S64.0 Injury of ulnar nerve at wrist and hand level	0.000	0.998	0.002
S56.20 Unspecified injury of other flexor muscle, fascia and tendon at forearm level	0.001	0.998	0.000
C34.1 Upper lobe, bronchus or lung	0.000	0.998	0.002
H21.5 Other adhesions and disruptions of iris and ciliary body	0.000	0.998	0.001
S02.8 Fractures of other skull and facial bones	0.001	0.998	0.000
S51.0 Open wound of elbow	0.001	0.998	0.000
K81 Cholecystitis	0.002	0.998	0.000
S02 Fracture of skull and facial bones	0.002	0.998	0.000
S64 Injury of nerves at wrist and hand level	0.000	0.998	0.002
S02.70 Multiple fractures involving skull and facial bones (closed)	0.001	0.998	0.000
H18.5 Hereditary corneal dystrophies	0.000	0.998	0.002
N85.4 Malposition of uterus	0.002	0.998	0.000
S02.7 Multiple fractures involving skull and facial bones	0.001	0.998	0.000
S59.9 Unspecified injury of forearm	0.001	0.998	0.000
H20 Iridocyclitis	0.000	0.998	0.002
F43.1 Posttraumatic stress disorder	0.001	0.998	0.000
L30.9 Dermatitis, unspecified	0.000	0.998	0.002
S52.6 Fracture of lower end of both ulna and radius	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations