TreeWAS – Variant ID: rs12251307

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E10 Insulin-dependent diabetes mellitus	0.000	0.801	0.199
E10.9 Without complications	0.000	0.806	0.194
E10.1 With ketoacidosis	0.000	0.809	0.191
E10.3 With ophthalmic complications	0.000	0.810	0.190
E10.5 With peripheral circulatory complications	0.000	0.828	0.172
E10.2 With renal complications	0.000	0.837	0.163
E10.4 With neurological complications	0.000	0.843	0.157
E10.6 With other specified complications	0.000	0.849	0.151
E10.7 With multiple complications	0.000	0.857	0.143
E10.8 With unspecified complications	0.000	0.863	0.137
E10.0 With coma	0.000	0.885	0.115
E10-E14 Diabetes mellitus	0.000	0.930	0.070
E13 Other specified diabetes mellitus	0.000	0.944	0.056
E12 Malnutrition-related diabetes mellitus	0.000	0.950	0.050
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.950	0.050
E13.9 Without complications	0.000	0.954	0.046
E03 Other hypothyroidism	0.000	0.954	0.046
E03.9 Hypothyroidism, unspecified	0.000	0.954	0.046
E00-E07 Disorders of thyroid gland	0.000	0.955	0.045
E20-E35 Disorders of other endocrine glands	0.000	0.955	0.045
E40-E46 Malnutrition	0.000	0.955	0.045
E46 Unspecified protein-energy malnutrition	0.000	0.958	0.041
E13.8 With unspecified complications	0.000	0.960	0.040
E13.7 With multiple complications	0.000	0.960	0.040
E13.6 With other specified complications	0.000	0.960	0.040
E13.5 With peripheral circulatory complications	0.000	0.960	0.040
E13.4 With neurological complications	0.000	0.960	0.040
E13.3 With ophthalmic complications	0.000	0.960	0.040
E13.2 With renal complications	0.000	0.960	0.040
E13.1 With ketoacidosis	0.000	0.960	0.040
E13.0 With coma	0.000	0.960	0.040
E23 Hypofunction and other disorders of pituitary gland	0.000	0.962	0.038
E24 Cushing's syndrome	0.000	0.962	0.038
E27 Other disorders of adrenal gland	0.000	0.963	0.037
E03.8 Other specified hypothyroidism	0.000	0.963	0.037
E06 Thyroiditis	0.000	0.963	0.037
E26 Hyperaldosteronism	0.000	0.963	0.037
E12.9 Without complications	0.000	0.964	0.036
E12.8 With unspecified complications	0.000	0.964	0.036
E12.7 With multiple complications	0.000	0.964	0.036
E12.6 With other specified complications	0.000	0.964	0.036
E12.5 With peripheral circulatory complications	0.000	0.964	0.036
E12.4 With neurological complications	0.000	0.964	0.036
E12.3 With ophthalmic complications	0.000	0.964	0.036
E12.2 With renal complications	0.000	0.964	0.036
E12.1 With ketoacidosis	0.000	0.964	0.036
E12.0 With coma	0.000	0.964	0.036
E28 Ovarian dysfunction	0.000	0.965	0.035
E23.2 Diabetes insipidus	0.000	0.965	0.035
E65-E68 Obesity and other hyperalimentation	0.000	0.966	0.034
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.966	0.034
E24.9 Cushing's syndrome, unspecified	0.000	0.966	0.034
E03.5 Myxoedema coma	0.000	0.967	0.033
E03.4 Atrophy of thyroid (acquired)	0.000	0.967	0.033
E03.3 Postinfectious hypothyroidism	0.000	0.967	0.033
E03.1 Congenital hypothyroidism without goitre	0.000	0.967	0.033
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.967	0.033
E22 Hyperfunction of pituitary gland	0.000	0.967	0.033
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.967	0.033
E00 Congenital iodine-deficiency syndrome	0.000	0.967	0.033
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.967	0.032
E32 Diseases of thymus	0.000	0.967	0.032
E31 Polyglandular dysfunction	0.000	0.967	0.032
E30 Disorders of puberty, not elsewhere classified	0.000	0.967	0.032
E25 Adrenogenital disorders	0.000	0.967	0.032
E34 Other endocrine disorders	0.000	0.968	0.032
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.968	0.032
E45 Retarded development following protein-energy malnutrition	0.000	0.968	0.032
E43 Unspecified severe protein-energy malnutrition	0.000	0.968	0.032
E42 Marasmic kwashiorkor	0.000	0.968	0.032
E41 Nutritional marasmus	0.000	0.968	0.032
E40 Kwashiorkor	0.000	0.968	0.032
E27.8 Other specified disorders of adrenal gland	0.000	0.968	0.032
E20 Hypoparathyroidism	0.000	0.968	0.032
E07 Other disorders of thyroid	0.000	0.968	0.032
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.969	0.031
E50-E64 Other nutritional deficiencies	0.000	0.969	0.031
E27.2 Addisonian crisis	0.000	0.969	0.031
E23.6 Other disorders of pituitary gland	0.000	0.969	0.031
E26.0 Primary hyperaldosteronism	0.000	0.969	0.030
E29 Testicular dysfunction	0.000	0.970	0.030
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.970	0.030
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.970	0.029
E06.3 Autoimmune thyroiditis	0.000	0.971	0.029
E66 Obesity	0.000	0.971	0.029
E06.9 Thyroiditis, unspecified	0.000	0.972	0.028
E27.9 Disorder of adrenal gland, unspecified	0.000	0.972	0.028
E23.7 Disorder of pituitary gland, unspecified	0.000	0.972	0.028
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.972	0.028
E23.1 Drug-induced hypopituitarism	0.000	0.972	0.028
E24.8 Other Cushing's syndrome	0.000	0.972	0.027
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.972	0.027
E24.3 Ectopic ACTH syndrome	0.000	0.972	0.027
E24.1 Nelson's syndrome	0.000	0.972	0.027
E24.0 Pituitary-dependent Cushing's disease	0.000	0.972	0.027
E22.0 Acromegaly and pituitary gigantism	0.000	0.972	0.028
E66.8 Other obesity	0.000	0.973	0.027
E28.2 Polycystic ovarian syndrome	0.000	0.973	0.027
E27.1 Primary adrenocortical insufficiency	0.000	0.973	0.027
E55 Vitamin D deficiency	0.000	0.973	0.027
E27.5 Adrenomedullary hyperfunction	0.000	0.973	0.027
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.973	0.027
E27.0 Other adrenocortical overactivity	0.000	0.973	0.027
E06.5 Other chronic thyroiditis	0.000	0.973	0.026
E06.4 Drug-induced thyroiditis	0.000	0.973	0.026
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.973	0.026
E06.1 Subacute thyroiditis	0.000	0.973	0.026
E06.0 Acute thyroiditis	0.000	0.973	0.026
E24.2 Drug-induced Cushing's syndrome	0.000	0.973	0.026
E26.9 Hyperaldosteronism, unspecified	0.000	0.973	0.026
E26.8 Other hyperaldosteronism	0.000	0.973	0.026
E26.1 Secondary hyperaldosteronism	0.000	0.973	0.026
E34.0 Carcinoid syndrome	0.000	0.974	0.026
E11 Non-insulin-dependent diabetes mellitus	0.000	0.974	0.026
E28.9 Ovarian dysfunction, unspecified	0.000	0.975	0.025
E28.8 Other ovarian dysfunction	0.000	0.975	0.025
E28.1 Androgen excess	0.000	0.975	0.025
E28.0 Oestrogen excess	0.000	0.975	0.025
E28.3 Primary ovarian failure	0.000	0.975	0.025
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.975	0.025
E67 Other hyperalimentation	0.000	0.975	0.025
E68 Sequelae of hyperalimentation	0.000	0.975	0.025
E22.1 Hyperprolactinaemia	0.000	0.976	0.024
E55.9 Vitamin D deficiency, unspecified	0.000	0.976	0.024
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.976	0.024
E22.8 Other hyperfunction of pituitary gland	0.000	0.976	0.024
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.976	0.024
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.976	0.024
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.976	0.024
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.976	0.024
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.976	0.024
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.976	0.024
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.976	0.024
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.976	0.024
E25.9 Adrenogenital disorder, unspecified	0.000	0.976	0.023
E25.8 Other adrenogenital disorders	0.000	0.976	0.023
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.976	0.023
E30.9 Disorder of puberty, unspecified	0.000	0.976	0.023
E30.8 Other disorders of puberty	0.000	0.976	0.023
E30.1 Precocious puberty	0.000	0.976	0.023
E30.0 Delayed puberty	0.000	0.976	0.023
E31.9 Polyglandular dysfunction, unspecified	0.000	0.976	0.023
E31.8 Other polyglandular dysfunction	0.000	0.976	0.023
E31.1 Polyglandular hyperfunction	0.000	0.976	0.023
E31.0 Autoimmune polyglandular failure	0.000	0.976	0.023
E32.9 Disease of thymus, unspecified	0.000	0.976	0.023
E32.8 Other diseases of thymus	0.000	0.976	0.023
E32.1 Abscess of thymus	0.000	0.976	0.023
E32.0 Persistent hyperplasia of thymus	0.000	0.976	0.023
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.976	0.023
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.976	0.023
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.976	0.023
E34.5 Androgen resistance syndrome	0.000	0.976	0.023
E34.4 Constitutional tall stature	0.000	0.976	0.023
E34.3 Short stature, not elsewhere classified	0.000	0.976	0.023
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.976	0.023
E34.1 Other hypersecretion of intestinal hormones	0.000	0.976	0.023
E44.1 Mild protein-energy malnutrition	0.000	0.977	0.023
E44.0 Moderate protein-energy malnutrition	0.000	0.977	0.023
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.977	0.023
E20.8 Other hypoparathyroidism	0.000	0.977	0.023
E20.1 Pseudohypoparathyroidism	0.000	0.977	0.023
E20.0 Idiopathic hypoparathyroidism	0.000	0.977	0.023
E07.9 Disorder of thyroid, unspecified	0.000	0.977	0.023
E07.1 Dyshormogenetic goitre	0.000	0.977	0.023
E07.0 Hypersecretion of calcitonin	0.000	0.977	0.023
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.977	0.023
E34.9 Endocrine disorder, unspecified	0.000	0.977	0.023
E15 Nondiabetic hypoglycaemic coma	0.000	0.977	0.022
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.977	0.022
E63 Other nutritional deficiencies	0.000	0.977	0.022
E56 Other vitamin deficiencies	0.000	0.977	0.022
E51 Thiamine deficiency	0.000	0.977	0.022
E50 Vitamin A deficiency	0.000	0.977	0.022
E60 Dietary zinc deficiency	0.000	0.977	0.022
E59 Dietary selenium deficiency	0.000	0.977	0.022
E54 Ascorbic acid deficiency	0.000	0.977	0.022
E52 Niacin deficiency [pellagra]	0.000	0.977	0.022
E20.9 Hypoparathyroidism, unspecified	0.000	0.978	0.022
E29.9 Testicular dysfunction, unspecified	0.000	0.978	0.022
E29.8 Other testicular dysfunction	0.000	0.978	0.022
E29.0 Testicular hyperfunction	0.000	0.978	0.022
E05.5 Thyroid crisis or storm	0.000	0.978	0.022
E05.4 Thyrotoxicosis factitia	0.000	0.978	0.022
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.978	0.022
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.978	0.022
E07.8 Other specified disorders of thyroid	0.000	0.978	0.022
E66.1 Drug-induced obesity	0.000	0.979	0.021
E11.5 With peripheral circulatory complications	0.000	0.979	0.021
E11.0 With coma	0.000	0.979	0.021
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.979	0.021
E66.0 Obesity due to excess calories	0.000	0.980	0.020
E34.8 Other specified endocrine disorders	0.000	0.980	0.020
E58 Dietary calcium deficiency	0.000	0.980	0.020
E23.0 Hypopituitarism	0.000	0.980	0.020
E55.0 Rickets, active	0.000	0.980	0.019
E05.8 Other thyrotoxicosis	0.000	0.981	0.019
E29.1 Testicular hypofunction	0.000	0.981	0.019
E61 Deficiency of other nutrient elements	0.000	0.981	0.019
E11.8 With unspecified complications	0.000	0.981	0.019
E11.1 With ketoacidosis	0.000	0.981	0.019
E11.7 With multiple complications	0.000	0.981	0.019
E11.4 With neurological complications	0.000	0.981	0.019
E67.8 Other specified hyperalimentation	0.000	0.982	0.018
E67.3 Hypervitaminosis D	0.000	0.982	0.018
E67.2 Megavitamin-B6 syndrome	0.000	0.982	0.018
E67.1 Hypercarotenaemia	0.000	0.982	0.018
E67.0 Hypervitaminosis A	0.000	0.982	0.018
E04 Other non-toxic goitre	0.000	0.982	0.018
E16 Other disorders of pancreatic internal secretion	0.000	0.982	0.018
E11.6 With other specified complications	0.000	0.982	0.018
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.983	0.017
E50.9 Vitamin A deficiency, unspecified	0.000	0.984	0.016
E50.8 Other manifestations of vitamin A deficiency	0.000	0.984	0.016
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.984	0.016
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.984	0.016
E50.5 Vitamin A deficiency with night blindness	0.000	0.984	0.016
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.984	0.016
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.984	0.016
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.984	0.016
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.984	0.016
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.984	0.016
E51.9 Thiamine deficiency, unspecified	0.000	0.984	0.016
E51.8 Other manifestations of thiamine deficiency	0.000	0.984	0.016
E51.2 Wernicke's encephalopathy	0.000	0.984	0.016
E51.1 Beriberi	0.000	0.984	0.016
E56.9 Vitamin deficiency, unspecified	0.000	0.984	0.016
E56.8 Deficiency of other vitamins	0.000	0.984	0.016
E56.1 Deficiency of vitamin K	0.000	0.984	0.016
E56.0 Deficiency of vitamin E	0.000	0.984	0.016
E63.9 Nutritional deficiency, unspecified	0.000	0.984	0.016
E63.8 Other specified nutritional deficiencies	0.000	0.984	0.016
E63.1 Imbalance of constituents of food intake	0.000	0.984	0.016
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.984	0.016
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.984	0.016
E64.8 Sequelae of other nutritional deficiencies	0.000	0.984	0.016
E64.3 Sequelae of rickets	0.000	0.984	0.016
E64.2 Sequelae of vitamin C deficiency	0.000	0.984	0.016
E64.1 Sequelae of vitamin A deficiency	0.000	0.984	0.016
E64.0 Sequelae of protein-energy malnutrition	0.000	0.984	0.016
E53 Deficiency of other B group vitamins	0.000	0.984	0.016
E11.2 With renal complications	0.000	0.984	0.016
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.985	0.015
E21.4 Other specified disorders of parathyroid gland	0.000	0.985	0.015
E65 Localised adiposity	0.001	0.985	0.014
E21.0 Primary hyperparathyroidism	0.000	0.985	0.015
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.985	0.014
E11.3 With ophthalmic complications	0.000	0.985	0.015
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.986	0.014
E61.9 Deficiency of nutrient element, unspecified	0.000	0.986	0.014
E61.8 Deficiency of other specified nutrient elements	0.000	0.986	0.014
E61.7 Deficiency of multiple nutrient elements	0.000	0.986	0.014
E61.6 Vanadium deficiency	0.000	0.986	0.014
E61.5 Molybdenum deficiency	0.000	0.986	0.014
E61.4 Chromium deficiency	0.000	0.986	0.014
E61.3 Manganese deficiency	0.000	0.986	0.014
E61.0 Copper deficiency	0.000	0.986	0.014
E04.9 Non-toxic goitre, unspecified	0.000	0.986	0.014
E61.2 Magnesium deficiency	0.000	0.986	0.013
E04.8 Other specified non-toxic goitre	0.000	0.987	0.013
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.987	0.013
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.987	0.013
E16.4 Abnormal secretion of gastrin	0.000	0.987	0.013
E16.3 Increased secretion of glucagon	0.000	0.987	0.013
E14 Unspecified diabetes mellitus	0.000	0.987	0.013
E04.0 Non-toxic diffuse goitre	0.000	0.987	0.013
M16.9 Coxarthrosis, unspecified	0.000	0.987	0.013
E05.9 Thyrotoxicosis, unspecified	0.000	0.987	0.013
E16.1 Other hypoglycaemia	0.000	0.987	0.013
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.988	0.012
E21.2 Other hyperparathyroidism	0.000	0.988	0.012
E53.9 Vitamin B deficiency, unspecified	0.000	0.988	0.012
E53.1 Pyridoxine deficiency	0.000	0.988	0.012
E53.0 Riboflavin deficiency	0.000	0.988	0.012
E61.1 Iron deficiency	0.000	0.989	0.011
E04.1 Non-toxic single thyroid nodule	0.000	0.990	0.010
E16.2 Hypoglycaemia, unspecified	0.000	0.990	0.010
E14.7 With multiple complications	0.000	0.990	0.009
E14.6 With other specified complications	0.000	0.990	0.009
E14.5 With peripheral circulatory complications	0.000	0.990	0.009
E14.4 With neurological complications	0.000	0.990	0.009
E14.2 Withrenal complications	0.000	0.990	0.009
E14.0 With coma	0.000	0.990	0.009
E66.9 Obesity, unspecified	0.000	0.991	0.009
E21.3 Hyperparathyroidism, unspecified	0.000	0.991	0.009
M16 Coxarthrosis [arthrosis of hip]	0.000	0.991	0.009
R13 Dysphagia	0.009	0.991	0.000
M16.7 Other secondary coxarthrosis	0.000	0.991	0.009
E14.8 With unspecified complications	0.000	0.991	0.009
E14.1 With ketoacidosis	0.000	0.992	0.008
M16.1 Other primary coxarthrosis	0.000	0.992	0.008
M16.5 Other posttraumatic coxarthrosis	0.000	0.992	0.008
N42.9 Disorder of prostate, unspecified	0.000	0.993	0.007
A08.4 Viral intestinal infection, unspecified	0.007	0.993	0.000
D86.9 Sarcoidosis, unspecified	0.000	0.993	0.007
M20.5 Other deformities of toe(s) (acquired)	0.000	0.993	0.007
M16.4 Posttraumatic coxarthrosis, bilateral	0.000	0.993	0.007
M16.2 Coxarthrosis resulting from dysplasia, bilateral	0.000	0.993	0.007
M16.3 Other dysplastic coxarthrosis	0.000	0.993	0.007
D86 Sarcoidosis	0.000	0.993	0.007
S72.00 Fracture of neck of femur (closed)	0.006	0.994	0.000
D86.8 Sarcoidosis of other and combined sites	0.000	0.994	0.006
M16.6 Other secondary coxarthrosis, bilateral	0.000	0.994	0.006
D86.0 Sarcoidosis of lung	0.000	0.994	0.006
S80.9 Superficial injury of lower leg, unspecified	0.000	0.994	0.006
A08 Viral and other specified intestinal infections	0.006	0.994	0.000
A08.3 Other viral enteritis	0.006	0.994	0.000
M20.4 Other hammer toe(s) (acquired)	0.000	0.994	0.006
T84.0 Mechanical complication of internal joint prosthesis	0.000	0.995	0.005
M16.0 Primary coxarthrosis, bilateral	0.000	0.995	0.005
D86.1 Sarcoidosis of lymph nodes	0.000	0.995	0.005
E14.3 With ophthalmic complications	0.000	0.995	0.005
D86.3 Sarcoidosis of skin	0.000	0.995	0.005
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.995	0.005
A08.1 Acute gastro-enteropathy due to Norwalk agent	0.005	0.995	0.000
Y60.0 During surgical operation	0.000	0.995	0.005
A08.5 Other specified intestinal infections	0.004	0.995	0.000
A08.2 Adenoviral enteritis	0.004	0.995	0.000
A08.0 Rotaviral enteritis	0.004	0.995	0.000
E53.8 Deficiency of other specified B group vitamins	0.000	0.995	0.004
S72.0 Fracture of neck of femur	0.004	0.996	0.000
M19.01 Primary arthrosis of other joints (Shoulder region)	0.000	0.996	0.004
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene	0.000	0.996	0.004
M20 Acquired deformities of fingers and toes	0.000	0.996	0.004
H18.1 Bullous keratopathy	0.003	0.996	0.000
H18 Other disorders of cornea	0.004	0.996	0.000
H18.2 Other corneal oedema	0.003	0.997	0.000
Q61.3 Polycystic kidney, unspecified	0.003	0.997	0.000
M19.04 Primary arthrosis of other joints (Hand)	0.000	0.997	0.003
I61.9 Intracerebral haemorrhage, unspecified	0.003	0.997	0.000
M19.0 Primary arthrosis of other joints	0.000	0.997	0.003
Q61 Cystic kidney disease	0.003	0.997	0.000
H18.6 Keratoconus	0.003	0.997	0.000
Q61.2 Polycystic kidney, adult type	0.003	0.997	0.000
S32.50 Fracture of pubis (closed)	0.000	0.997	0.003
Z34.8 Supervision of other normal pregnancy	0.000	0.997	0.003
M20.6 Acquired deformity of toe(s), unspecified	0.000	0.997	0.003
M19.09 Primary arthrosis of other joints (Site unspecified)	0.000	0.997	0.003
S72.01 Fracture of neck of femur (open)	0.003	0.997	0.000
Q61.4 Renal dysplasia	0.003	0.997	0.000
M19.03 Primary arthrosis of other joints (Forearm)	0.000	0.997	0.003
H18.9 Disorder of cornea, unspecified	0.003	0.997	0.000
H18.5 Hereditary corneal dystrophies	0.003	0.997	0.000
H18.8 Other specified disorders of cornea	0.003	0.997	0.000
Q61.0 Congenital single renal cyst	0.003	0.997	0.000
E04.2 Non-toxic multinodular goitre	0.001	0.997	0.002
J93.8 Other pneumothorax	0.003	0.997	0.000
K35.9 Acute appendicitis, unspecified	0.000	0.997	0.003
H18.7 Other corneal deformities	0.003	0.997	0.000
H18.3 Changes in corneal membranes	0.003	0.997	0.000
H18.0 Corneal pigmentations and deposits	0.003	0.997	0.000
M19.02 Primary arthrosis of other joints (Upper arm)	0.000	0.997	0.003
I50.1 Left ventricular failure	0.000	0.997	0.003
S62.60 Fracture of other finger (closed)	0.000	0.997	0.003
M19.08 Primary arthrosis of other joints (Other)	0.000	0.997	0.003
M19.06 Primary arthrosis of other joints-Lower leg	0.000	0.997	0.003
M19.05 Primary arthrosis of other joints (Pelvic region and thigh)	0.000	0.997	0.003
M19.00 Primary arthrosis of other joints (Multiple sites)	0.000	0.997	0.003
Q61.9 Cystic kidney disease, unspecified	0.003	0.997	0.000
Q61.8 Other cystic kidney diseases	0.003	0.997	0.000
Q61.1 Polycystic kidney, infantile type	0.003	0.997	0.000
A87.9 Viral meningitis, unspecified	0.000	0.997	0.003
T84.2 Mechanical complication of internal fixation device of other bones	0.000	0.997	0.003
Y43.3 Other antineoplastic drugs	0.003	0.997	0.000
D80-D89 Certain disorders involving the immune mechanism	0.000	0.997	0.003
M75.0 Adhesive capsulitis of shoulder	0.003	0.997	0.000
S32.5 Fracture of pubis	0.000	0.997	0.003
Q61.5 Medullary cystic kidney	0.002	0.997	0.000
H50.0 Convergent concomitant strabismus	0.002	0.997	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.002	0.997	0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.000	0.997	0.002
I63.9 Cerebral infarction, unspecified	0.002	0.998	0.000
M94.86 Other specified disorders of cartilage (Lower leg)	0.002	0.998	0.000
G61.0 Guillain-Barre syndrome	0.002	0.998	0.000
M94.8 Other specified disorders of cartilage	0.002	0.998	0.000
Z35.1 Supervision of pregnancy with history of abortive outcome	0.000	0.998	0.002
M94.87 Other specified disorders of cartilage (Ankle and foot)	0.002	0.998	0.000
Z36.9 Antenatal screening, unspecified	0.000	0.998	0.002
W20.0 Home	0.002	0.998	0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.000	0.998	0.002
I60 Subarachnoid haemorrhage	0.002	0.998	0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.000	0.998	0.002
S32.80 Fracture of other and unspecified parts of lumbar spine and pelvis (closed)	0.000	0.998	0.002
I61 Intracerebral haemorrhage	0.002	0.998	0.000
D80 Immunodeficiency with predominantly antibody defects	0.000	0.998	0.002
I60.9 Subarachnoid haemorrhage, unspecified	0.002	0.998	0.000
Q66.2 Metatarsus varus	0.002	0.998	0.000
H50 Other strabismus	0.002	0.998	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.002	0.998	0.000
M20.2 Hallux rigidus	0.000	0.998	0.002
Q66 Congenital deformities of feet	0.002	0.998	0.000
Q60-Q64 Congenital malformations of the urinary system	0.002	0.998	0.000
M47.92 Spondylosis, unspecified (Cervical region)	0.000	0.998	0.002
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.000	0.998	0.002
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.002	0.998	0.000
H18.4 Corneal degeneration	0.002	0.998	0.000
H50.5 Heterophoria	0.002	0.998	0.000
H50.1 Divergent concomitant strabismus	0.002	0.998	0.000
Z86.5 Personal history of other mental and behavioural disorders	0.000	0.998	0.002
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.002	0.998	0.000
M20.3 Other deformity of hallux (acquired)	0.000	0.998	0.002
Q66.9 Congenital deformity of feet, unspecified	0.002	0.998	0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.000	0.998	0.002
Z91.0 Personal history of allergy, other than to drugs and biological substances	0.002	0.998	0.000
M94.26 Chondromalacia (Lower leg)	0.002	0.998	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.002	0.998	0.000
S80.1 Contusion of other and unspecified parts of lower leg	0.000	0.998	0.002
D83 Common variable immunodeficiency	0.000	0.998	0.002
D82 Immunodeficiency associated with other major defects	0.000	0.998	0.002
D81 Combined immunodeficiencies	0.000	0.998	0.002
N48.6 Balanitis xerotica obliterans	0.000	0.998	0.002
S32.7 Multiple fractures of lumbar spine and pelvis	0.000	0.998	0.002
S32.51 Fracture of pubis (open)	0.000	0.998	0.002
G60.0 Hereditary motor and sensory neuropathy	0.002	0.998	0.000
M20.0 Deformity of finger(s)	0.000	0.998	0.002
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.000	0.998	0.002
I69 Sequelae of cerebrovascular disease	0.002	0.998	0.000
A00-A09 Intestinal infectious diseases	0.002	0.998	0.000
M94.88 Other specified disorders of cartilage (Other)	0.002	0.998	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.000	0.998	0.002
J93.0 Spontaneous tension pneumothorax	0.002	0.998	0.000
D84 Other immunodeficiencies	0.000	0.998	0.002
Q64 Other congenital malformations of urinary system	0.002	0.998	0.000
A04.5 Campylobacter enteritis	0.002	0.998	0.000
M94.2 Chondromalacia	0.002	0.998	0.000
S32 Fracture of lumbar spine and pelvis	0.000	0.998	0.002
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.002	0.998	0.000
M94 Other disorders of cartilage	0.002	0.998	0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.000	0.998	0.002
M25.76 Osteophyte (Lower leg)	0.002	0.998	0.000
M94.85 Other specified disorders of cartilage (Pelvic region and thigh)	0.002	0.998	0.000
M94.84 Other specified disorders of cartilage (Hand)	0.002	0.998	0.000
M94.83 Other specified disorders of cartilage (Forearm)	0.002	0.998	0.000
M94.82 Other specified disorders of cartilage (Upper arm)	0.002	0.998	0.000
M94.81 Other specified disorders of cartilage (Shoulder region)	0.002	0.998	0.000
M94.80 Other specified disorders of cartilage (Multiple sites)	0.002	0.998	0.000
S72.40 Fracture of lower end of femur (closed)	0.002	0.998	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.002	0.998	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.002	0.998	0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.002	0.998	0.000
J93 Pneumothorax	0.002	0.998	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.002	0.998	0.000
S72 Fracture of femur	0.002	0.998	0.000
W20 Struck by thrown, projected or falling object	0.002	0.998	0.000
E14.9 Without complications	0.000	0.998	0.002
E85.9 Amyloidosis, unspecified	0.000	0.998	0.002
Q67.6 Pectus excavatum	0.002	0.998	0.000
S72.4 Fracture of lower end of femur	0.002	0.998	0.000
S80 Superficial injury of lower leg	0.000	0.998	0.002
I60-I69 Cerebrovascular diseases	0.002	0.998	0.000
H17.8 Other corneal scars and opacities	0.002	0.998	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.002	0.998	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.002	0.998	0.000
I60.5 Subarachnoid haemorrhage from vertebral artery	0.002	0.998	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.002	0.998	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.002	0.998	0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.002	0.998	0.000
H16 Keratitis	0.002	0.998	0.000
M94.89 Other specified disorders of cartilage (Site unspecified)	0.002	0.998	0.000
I61.8 Other intracerebral haemorrhage	0.002	0.998	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.002	0.998	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.002	0.998	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.002	0.998	0.000
J93.1 Other spontaneous pneumothorax	0.002	0.998	0.000
E85 Amyloidosis	0.000	0.998	0.002
E70-E90 Metabolic disorders	0.000	0.998	0.002
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.000	0.998	0.002
D80.8 Other immunodeficiencies with predominantly antibody defects	0.000	0.998	0.002
D80.7 Transient hypogammaglobulinaemia of infancy	0.000	0.998	0.002
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.000	0.998	0.002
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.000	0.998	0.002
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.000	0.998	0.002
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.000	0.998	0.002
D80.0 Hereditary hypogammaglobulinaemia	0.000	0.998	0.002
H17 Corneal scars and opacities	0.002	0.998	0.000
I63 Cerebral infarction	0.002	0.998	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.000	0.998	0.002
H16.9 Keratitis, unspecified	0.002	0.998	0.000
H50.9 Strabismus, unspecified	0.002	0.998	0.000
H50.8 Other specified strabismus	0.002	0.998	0.000
H50.6 Mechanical strabismus	0.002	0.998	0.000
H50.4 Other and unspecified heterotropia	0.002	0.998	0.000
H50.3 Intermittent heterotropia	0.002	0.998	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.002	0.998	0.000
I67.8 Other specified cerebrovascular diseases	0.002	0.998	0.000
M94.9 Disorder of cartilage, unspecified	0.002	0.998	0.000
Q66.7 Pes cavus	0.002	0.998	0.000
Q66.6 Other congenital valgus deformities of feet	0.002	0.998	0.000
Q66.5 Congenital pes planus	0.002	0.998	0.000
Q66.4 Talipes calcaneovalgus	0.002	0.998	0.000
Q66.1 Talipes calcaneovarus	0.002	0.998	0.000
Q66.0 Talipes equinovarus	0.002	0.998	0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.002	0.998	0.000
Q66.8 Other congenital deformities of feet	0.002	0.998	0.000
Q66.3 Other congenital varus deformities of feet	0.002	0.998	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.002	0.998	0.000
L89.1 Stage II decubitus ulcer	0.002	0.998	0.000
Q44.6 Cystic disease of liver	0.002	0.998	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.002	0.998	0.000
Q76 Congenital malformations of spine and bony thorax	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations