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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12281359
log Bayes Factor = 0.0524276
Chromosome 11   position 70,417,181  (GRCh37) Explore rs12281359 on Ensembl!
Variant rs12281359 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
G50-G59 Nerve, nerve root and plexus disorders
0.097 0.903 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.097 0.903 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.096 0.904 0.000
Chapter VI Diseases of the nervous system
0.088 0.912 0.000
G50 Disorders of trigeminal nerve
0.086 0.914 0.000
G30-G32 Other degenerative diseases of the nervous system
0.083 0.917 0.000
G50.0 Trigeminal neuralgia
0.078 0.922 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.078 0.922 0.000
G55.0 Nerve root and plexus compressions in neoplastic disease
0.078 0.922 0.000
G54 Nerve root and plexus disorders
0.077 0.923 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.076 0.923 0.000
G57 Mononeuropathies of lower limb
0.076 0.924 0.000
G51 Facial nerve disorders
0.075 0.925 0.000
G20-G26 Extrapyramidal and movement disorders
0.073 0.927 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.073 0.927 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.070 0.930 0.000
G90-G99 Other disorders of the nervous system
0.070 0.930 0.000
G55.3 Nerve root and plexus compressions in other dorsopathies
0.070 0.930 0.000
G52 Disorders of other cranial nerves
0.069 0.930 0.000
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere
0.069 0.931 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.069 0.931 0.000
G30 Alzheimer's disease
0.068 0.932 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.067 0.933 0.000
G56 Mononeuropathies of upper limb
0.066 0.933 0.000
G55.2 Nerve root and plexus compressions in spondylosis
0.065 0.935 0.000
G31.0 Circumscribed brain atrophy
0.065 0.935 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.065 0.935 0.000
G70-G73 Diseases of myoneural junction and muscle
0.064 0.935 0.000
D70 Agranulocytosis
0.064 0.936 0.000
G58 Other mononeuropathies
0.064 0.936 0.000
G57.6 Lesion of plantar nerve
0.063 0.936 0.000
G54.9 Nerve root and plexus disorder, unspecified
0.063 0.937 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.062 0.938 0.000
G59.0 Diabetic mononeuropathy
0.062 0.938 0.000
G24 Dystonia
0.062 0.938 0.000
G50.9 Disorder of trigeminal nerve, unspecified
0.062 0.938 0.000
G50.8 Other disorders of trigeminal nerve
0.062 0.938 0.000
G50.1 Atypical facial pain
0.062 0.938 0.000
D69 Purpura and other haemorrhagic conditions
0.062 0.938 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.062 0.938 0.000
G91 Hydrocephalus
0.061 0.939 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.060 0.940 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.060 0.940 0.000
D69.6 Thrombocytopenia, unspecified
0.059 0.941 0.000
G90 Disorders of autonomic nervous system
0.059 0.941 0.000
G31.8 Other specified degenerative diseases of nervous system
0.059 0.941 0.000
G51.0 Bell's palsy
0.059 0.941 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.059 0.941 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.059 0.941 0.000
G20 Parkinson's disease
0.058 0.942 0.000
H53 Visual disturbances
0.058 0.942 0.000
H53.8 Other visual disturbances
0.057 0.943 0.000
H53-H54 Visual disturbances and blindness
0.057 0.943 0.000
G30.9 Alzheimer's disease, unspecified
0.057 0.943 0.000
G31.2 Degeneration of nervous system due to alcohol
0.056 0.944 0.000
G31.1 Senile degeneration of brain, not elsewhere classified
0.056 0.944 0.000
G53.0 Postzoster neuralgia
0.056 0.944 0.000
G57.1 Meralgia paraesthetica
0.056 0.944 0.000
D68 Other coagulation defects
0.056 0.944 0.000
G37 Other demyelinating diseases of central nervous system
0.056 0.944 0.000
G54.8 Other nerve root and plexus disorders
0.055 0.945 0.000
G54.7 Phantom limb syndrome without pain
0.055 0.945 0.000
G54.6 Phantom limb syndrome with pain
0.055 0.945 0.000
G54.5 Neuralgic amyotrophy
0.055 0.945 0.000
G54.4 Lumbosacral root disorders, not elsewhere classified
0.055 0.945 0.000
G54.3 Thoracic root disorders, not elsewhere classified
0.055 0.945 0.000
G54.2 Cervical root disorders, not elsewhere classified
0.055 0.945 0.000
G54.1 Lumbosacral plexus disorders
0.055 0.945 0.000
G54.0 Brachial plexus disorders
0.055 0.945 0.000
G59.8 Other mononeuropathies in diseases classified elsewhere
0.055 0.945 0.000
Chapter VII Diseases of the eye and adnexa
0.055 0.945 0.000
G56.0 Carpal tunnel syndrome
0.055 0.945 0.000
G57.9 Mononeuropathy of lower limb, unspecified
0.054 0.945 0.000
G57.5 Tarsal tunnel syndrome
0.054 0.945 0.000
G57.4 Lesion of medial popliteal nerve
0.054 0.945 0.000
G57.3 Lesion of lateral popliteal nerve
0.054 0.945 0.000
G57.2 Lesion of femoral nerve
0.054 0.945 0.000
G57.0 Lesion of sciatic nerve
0.054 0.945 0.000
G95 Other diseases of spinal cord
0.054 0.946 0.000
G51.9 Disorder of facial nerve, unspecified
0.054 0.946 0.000
G51.8 Other disorders of facial nerve
0.054 0.946 0.000
G51.4 Facial myokymia
0.054 0.946 0.000
G51.3 Clonic hemifacial spasm
0.054 0.946 0.000
G51.2 Melkersson's syndrome
0.054 0.946 0.000
G51.1 Geniculate ganglionitis
0.054 0.946 0.000
G24.9 Dystonia, unspecified
0.054 0.946 0.000
G23 Other degenerative diseases of basal ganglia
0.053 0.947 0.000
G21 Secondary Parkinsonism
0.053 0.947 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.053 0.947 0.000
G22 Parkinsonism in diseases classified elsewhere
0.053 0.947 0.000
G53.8 Other cranial nerve disorders in other diseases classified elsewhere
0.053 0.947 0.000
G53.3 Multiple cranial nerve palsies in neoplastic disease
0.053 0.947 0.000
G53.2 Multiple cranial nerve palsies in sarcoidosis
0.053 0.947 0.000
G53.1 Multiple cranial nerve palsies in infectious and parasitic diseases classified elsewhere
0.053 0.947 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.053 0.947 0.000
G91.1 Obstructive hydrocephalus
0.053 0.947 0.000
H53.2 Diplopia
0.052 0.948 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.051 0.949 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.051 0.949 0.000
M20-M25 Other joint disorders
0.051 0.949 0.000
G81 Hemiplegia
0.051 0.949 0.000
# Top node
0.051 0.949 0.000
D66 Hereditary factor VIII deficiency
0.051 0.949 0.000
G61 Inflammatory polyneuropathy
0.050 0.950 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.050 0.950 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.050 0.950 0.000
G92 Toxic encephalopathy
0.050 0.950 0.000
M25 Other joint disorders, not elsewhere classified
0.050 0.950 0.000
G52.9 Cranial nerve disorder, unspecified
0.050 0.950 0.000
G52.8 Disorders of other specified cranial nerves
0.050 0.950 0.000
G52.7 Disorders of multiple cranial nerves
0.050 0.950 0.000
G52.3 Disorders of hypoglossal nerve
0.050 0.950 0.000
G52.2 Disorders of vagus nerve
0.050 0.950 0.000
G52.1 Disorders of glossopharyngeal nerve
0.050 0.950 0.000
G52.0 Disorders of olfactory nerve
0.050 0.950 0.000
G36 Other acute disseminated demyelination
0.050 0.950 0.000
G82 Paraplegia and tetraplegia
0.050 0.950 0.000
G35 Multiple sclerosis
0.049 0.951 0.000
H53.1 Subjective visual disturbances
0.049 0.951 0.000
D69.5 Secondary thrombocytopenia
0.049 0.951 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.049 0.951 0.000
G30.8 Other Alzheimer's disease
0.049 0.951 0.000
G30.1 Alzheimer's disease with late onset
0.049 0.951 0.000
G30.0 Alzheimer's disease with early onset
0.049 0.951 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.049 0.951 0.000
G90.9 Disorder of autonomic nervous system, unspecified
0.049 0.951 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.049 0.951 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.048 0.951 0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.048 0.951 0.000
G03 Meningitis due to other and unspecified causes
0.048 0.951 0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.048 0.951 0.000
G00 Bacterial meningitis, not elsewhere classified
0.048 0.951 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.048 0.951 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.048 0.951 0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.048 0.951 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.048 0.951 0.000
H54 Blindness and low vision
0.048 0.952 0.000
G25 Other extrapyramidal and movement disorders
0.048 0.952 0.000
G56.9 Mononeuropathy of upper limb, unspecified
0.048 0.952 0.000
G56.8 Other mononeuropathies of upper limb
0.048 0.952 0.000
G56.4 Causalgia
0.048 0.952 0.000
G56.3 Lesion of radial nerve
0.048 0.952 0.000
G56.1 Other lesions of median nerve
0.048 0.952 0.000
G70 Myasthenia gravis and other myoneural disorders
0.048 0.952 0.000
G91.9 Hydrocephalus, unspecified
0.048 0.952 0.000
G96 Other disorders of central nervous system
0.048 0.952 0.000
D68.9 Coagulation defect, unspecified
0.047 0.952 0.000
G57.8 Other mononeuropathies of lower limb
0.047 0.952 0.000
G90.0 Idiopathic peripheral autonomic neuropathy
0.047 0.953 0.000
M23 Internal derangement of knee
0.047 0.953 0.000
H10-H13 Disorders of conjunctiva
0.047 0.953 0.000
M24 Other specific joint derangements
0.047 0.953 0.000
G58.8 Other specified mononeuropathies
0.046 0.953 0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere
0.046 0.953 0.000
G72 Other myopathies
0.046 0.953 0.000
G71 Primary disorders of muscles
0.046 0.953 0.000
M23.3 Other meniscus derangements
0.046 0.954 0.000
M15-M19 Arthrosis
0.046 0.954 0.000
G58.7 Mononeuritis multiplex
0.046 0.954 0.000
G58.0 Intercostal neuropathy
0.046 0.954 0.000
D68.5 Primary Thrombophilia
0.046 0.954 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.046 0.954 0.000
H50 Other strabismus
0.046 0.954 0.000
M19.9 Arthrosis, unspecified
0.046 0.954 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.045 0.954 0.000
M19 Other arthrosis
0.045 0.955 0.000
Chapter V Mental and behavioural disorders
0.045 0.955 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.045 0.955 0.000
D67 Hereditary factor IX deficiency
0.045 0.955 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.045 0.955 0.000
G24.8 Other dystonia
0.045 0.955 0.000
G24.5 Blepharospasm
0.045 0.955 0.000
G24.4 Idiopathic orofacial dystonia
0.045 0.955 0.000
G24.3 Spasmodic torticollis
0.045 0.955 0.000
G24.2 Idiopathic nonfamilial dystonia
0.045 0.955 0.000
G24.1 Idiopathic familial dystonia
0.045 0.955 0.000
G24.0 Drug-induced dystonia
0.045 0.955 0.000
G80 Infantile cerebral palsy
0.044 0.955 0.000
D69.9 Haemorrhagic condition, unspecified
0.044 0.955 0.000
D69.8 Other specified haemorrhagic conditions
0.044 0.955 0.000
D69.4 Other primary thrombocytopenia
0.044 0.955 0.000
D69.2 Other nonthrombocytopenic purpura
0.044 0.955 0.000
D69.1 Qualitative platelet defects
0.044 0.955 0.000
D69.0 Allergic purpura
0.044 0.955 0.000
G60 Hereditary and idiopathic neuropathy
0.044 0.956 0.000
G64 Other disorders of peripheral nervous system
0.044 0.956 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.044 0.956 0.000
G83 Other paralytic syndromes
0.044 0.956 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.044 0.956 0.000
M25.5 Pain in joint
0.044 0.956 0.000
G95.9 Disease of spinal cord, unspecified
0.044 0.956 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.044 0.956 0.000
G91.8 Other hydrocephalus
0.044 0.956 0.000
G91.3 Posttraumatic hydrocephalus, unspecified
0.044 0.956 0.000
G91.2 Normal-pressure hydrocephalus
0.044 0.956 0.000
G91.0 Communicating hydrocephalus
0.044 0.956 0.000
H18 Other disorders of cornea
0.044 0.956 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.043 0.956 0.000
D74 Methaemoglobinaemia
0.043 0.956 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.043 0.956 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.043 0.956 0.000
H52 Disorders of refraction and accommodation
0.043 0.957 0.000
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere
0.043 0.957 0.000
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere
0.043 0.957 0.000
D73 Diseases of spleen
0.043 0.957 0.000
M18 Arthrosis of first carpometacarpal joint
0.043 0.957 0.000
D68.8 Other specified coagulation defects
0.043 0.957 0.000
G95.1 Vascular myelopathies
0.043 0.957 0.000
G90.8 Other disorders of autonomic nervous system
0.043 0.957 0.000
G90.4 Autonomic dysreflexia
0.043 0.957 0.000
G90.3 Multisystem degeneration
0.043 0.957 0.000
G90.2 Horner's syndrome
0.043 0.957 0.000
G90.1 Familial dysautonomia [Riley-Day]
0.043 0.957 0.000
M34 Systemic sclerosis
0.043 0.957 0.000
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere
0.042 0.957 0.000
G11 Hereditary ataxia
0.042 0.957 0.000
G14 Postpolio syndrome
0.042 0.957 0.000
G10 Huntington's disease
0.042 0.957 0.000
G61.0 Guillain-Barre syndrome
0.042 0.958 0.000
D55-D59 Haemolytic anaemias
0.042 0.958 0.000
D72 Other disorders of white blood cells
0.042 0.958 0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified
0.042 0.958 0.000
M19.91 Arthrosis, unspecified (Shoulder region)
0.042 0.958 0.000
D75 Other diseases of blood and blood-forming organs
0.042 0.958 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.042 0.958 0.000
H53.6 Night blindness
0.042 0.958 0.000
H53.5 Colour vision deficiencies
0.042 0.958 0.000
H53.3 Other disorders of binocular vision
0.042 0.958 0.000
H54.9 Unspecified visual impairment (binocular)
0.042 0.958 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.041 0.958 0.000
M19.97 Arthrosis, unspecified (Ankle and foot)
0.041 0.959 0.000
M19.93 Arthrosis, unspecified (Forearm)
0.041 0.959 0.000
L20-L30 Dermatitis and eczema
0.041 0.959 0.000
L30 Other dermatitis
0.041 0.959 0.000
H52.1 Myopia
0.041 0.959 0.000
H53.9 Visual disturbance, unspecified
0.041 0.959 0.000
M25.3 Other instability of joint
0.041 0.959 0.000
M35 Other systemic involvement of connective tissue
0.041 0.959 0.000
G81.9 Hemiplegia, unspecified
0.040 0.960 0.000
D68.6 Other Thrombophilia
0.040 0.960 0.000
D68.4 Acquired coagulation factor deficiency
0.040 0.960 0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.040 0.960 0.000
D68.1 Hereditary factor XI deficiency
0.040 0.960 0.000
D68.0 Von Willebrand's disease
0.040 0.960 0.000
G58.9 Mononeuropathy, unspecified
0.040 0.960 0.000
G37.8 Other specified demyelinating diseases of central nervous system
0.040 0.960 0.000
G37.5 Concentric sclerosis [Balo]
0.040 0.960 0.000
G37.4 Subacute necrotising myelitis
0.040 0.960 0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.040 0.960 0.000
G37.2 Central pontine myelinolysis
0.040 0.960 0.000
G37.1 Central demyelination of corpus callosum
0.040 0.960 0.000
G37.0 Diffuse sclerosis
0.040 0.960 0.000
M91-M94 Chondropathies
0.040 0.960 0.000
H30-H36 Disorders of choroid and retina
0.040 0.960 0.000
H50.1 Divergent concomitant strabismus
0.040 0.960 0.000
M25.4 Effusion of joint
0.040 0.960 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.040 0.960 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.040 0.960 0.000
H11 Other disorders of conjunctiva
0.040 0.960 0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)
0.039 0.961 0.000
G95.0 Syringomyelia and syringobulbia
0.039 0.961 0.000
Chapter XXII Codes for special purposes
0.039 0.961 0.000
M25.53 Pain in joint (Forearm)
0.039 0.961 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.039 0.961 0.000
L30.9 Dermatitis, unspecified
0.039 0.961 0.000
G12 Spinal muscular atrophy and related syndromes
0.038 0.962 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.038 0.962 0.000
F60-F69 Disorders of adult personality and behaviour
0.038 0.962 0.000
H10 Conjunctivitis
0.038 0.962 0.000
G21.9 Secondary Parkinsonism, unspecified
0.038 0.962 0.000
G21.8 Other secondary Parkinsonism
0.038 0.962 0.000
G21.4 Vascular parkinsonism
0.038 0.962 0.000
G21.3 Postencephalitic Parkinsonism
0.038 0.962 0.000
G21.2 Secondary Parkinsonism due to other external agents
0.038 0.962 0.000
G21.1 Other drug-induced secondary Parkinsonism
0.038 0.962 0.000
G21.0 Malignant neuroleptic syndrome
0.038 0.962 0.000
G23.9 Degenerative disease of basal ganglia, unspecified
0.038 0.962 0.000
G23.8 Other specified degenerative diseases of basal ganglia
0.038 0.962 0.000
G23.3 Multiple system atrophy, cerebellar type
0.038 0.962 0.000
G23.2 Striatonigral degeneration
0.038 0.962 0.000
G23.1 Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]
0.038 0.962 0.000
G23.0 Hallervorden-Spatz disease
0.038 0.962 0.000
H54.0 Blindness, both eyes
0.038 0.962 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.038 0.962 0.000
G04.8 Other encephalitis, myelitis and encephalomyelitis
0.038 0.962 0.000
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified
0.038 0.962 0.000
G04.1 Tropical spastic paraplegia
0.038 0.962 0.000
G04.0 Acute disseminated encephalitis
0.038 0.962 0.000
H49 Paralytic strabismus
0.038 0.962 0.000
D68.2 Hereditary deficiency of other clotting factors
0.038 0.962 0.000
G82.1 Spastic paraplegia
0.038 0.962 0.000
H18.5 Hereditary corneal dystrophies
0.038 0.962 0.000
H50.0 Convergent concomitant strabismus
0.038 0.962 0.000
M24.2 Disorder of ligament
0.037 0.962 0.000
D80-D89 Certain disorders involving the immune mechanism
0.037 0.963 0.000
L30.8 Other specified dermatitis
0.037 0.963 0.000
M25.0 Haemarthrosis
0.037 0.963 0.000
M25.50 Pain in joint (Multiple sites)
0.037 0.963 0.000
M40-M43 Deforming dorsopathies
0.037 0.963 0.000
H17 Corneal scars and opacities
0.037 0.963 0.000
G95.2 Cord compression, unspecified
0.037 0.963 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.037 0.963 0.000
M24.1 Other articular cartilage disorders
0.037 0.963 0.000
H51 Other disorders of binocular movement
0.037 0.963 0.000
M23.9 Internal derangement of knee, unspecified
0.037 0.963 0.000
H54.7 Unspecified visual loss
0.037 0.963 0.000
M60-M63 Disorders of muscles
0.037 0.963 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.037 0.963 0.000
M33 Dermatopolymyositis
0.037 0.963 0.000
M32 Systemic lupus erythematosus
0.037 0.963 0.000
M30 Polyarteritis nodosa and related conditions
0.037 0.963 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.037 0.963 0.000
H18.4 Corneal degeneration
0.037 0.963 0.000
M25.7 Osteophyte
0.037 0.963 0.000
G82.2 Paraplegia, unspecified
0.036 0.963 0.000
H53.0 Amblyopia ex anopsia
0.037 0.963 0.000
G81.1 Spastic hemiplegia
0.036 0.963 0.000
G81.0 Flaccid hemiplegia
0.036 0.963 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.036 0.963 0.000
M23.5 Chronic instability of knee
0.036 0.963 0.000
H55-H59 Other disorders of eye and adnexa
0.036 0.963 0.000
M35.0 Sicca syndrome [Sjogren]
0.036 0.964 0.000
G61.9 Inflammatory polyneuropathy, unspecified
0.036 0.964 0.000
G61.8 Other inflammatory polyneuropathies
0.036 0.964 0.000
G61.1 Serum neuropathy
0.036 0.964 0.000
M25.9 Joint disorder, unspecified
0.036 0.964 0.000
M25.2 Flail joint
0.036 0.964 0.000
M25.1 Fistula of joint
0.036 0.964 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.036 0.964 0.000
G94.8 Other specified disorders of brain in diseases classified elsewhere
0.036 0.964 0.000
G94.2 Hydrocephalus in other diseases classified elsewhere
0.036 0.964 0.000
G94.1 Hydrocephalus in neoplastic disease
0.036 0.964 0.000
G94.0 Hydrocephalus in infectious and parasitic diseases classified elsewhere
0.036 0.964 0.000
M25.8 Other specified joint disorders
0.036 0.964 0.000
G25.3 Myoclonus
0.036 0.964 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.036 0.964 0.000
G70.0 Myasthenia gravis
0.036 0.964 0.000
G36.9 Acute disseminated demyelination, unspecified
0.036 0.964 0.000
G36.8 Other specified acute disseminated demyelination
0.036 0.964 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.036 0.964 0.000
G36.0 Neuromyelitis optica [Devic]
0.036 0.964 0.000
G82.5 Tetraplegia, unspecified
0.036 0.964 0.000
G82.4 Spastic tetraplegia
0.036 0.964 0.000
G82.3 Flaccid tetraplegia
0.036 0.964 0.000
G82.0 Flaccid paraplegia
0.036 0.964 0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)
0.036 0.964 0.000
M00-M03 Infectious arthropathies
0.036 0.964 0.000
F30-F39 Mood [affective] disorders
0.036 0.964 0.000
H40-H42 Glaucoma
0.036 0.964 0.000
F80-F89 Disorders of psychological development
0.035 0.964 0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)
0.035 0.964 0.000
M23.4 Loose body in knee
0.035 0.964 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.035 0.964 0.000
M25.57 Pain in joint (Ankle and foot)
0.035 0.965 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.035 0.965 0.000
M80-M85 Disorders of bone density and structure
0.035 0.965 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.035 0.965 0.000
G95.8 Other specified diseases of spinal cord
0.035 0.965 0.000
H50.2 Vertical strabismus
0.035 0.965 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.035 0.965 0.000
G97.9 Postprocedural disorder of nervous system, unspecified
0.035 0.965 0.000
G97.8 Other postprocedural disorders of nervous system
0.035 0.965 0.000
G97.2 Intracranial hypotension following ventricular shunting
0.035 0.965 0.000
G97.0 Cerebrospinal fluid leak from spinal puncture
0.035 0.965 0.000
M86-M90 Other osteopathies
0.035 0.965 0.000
H16 Keratitis
0.035 0.965 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.035 0.965 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.035 0.965 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.035 0.965 0.000
H15 Disorders of sclera
0.035 0.965 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.035 0.965 0.000
Q80-Q89 Other congenital malformations
0.035 0.965 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.035 0.965 0.000
M05-M14 Inflammatory polyarthropathies
0.035 0.965 0.000
G00.9 Bacterial meningitis, unspecified
0.035 0.965 0.000
G00.8 Other bacterial meningitis
0.035 0.965 0.000
G00.3 Staphylococcal meningitis
0.035 0.965 0.000
G00.2 Streptococcal meningitis
0.035 0.965 0.000
G00.1 Pneumococcal meningitis
0.035 0.965 0.000
G00.0 Haemophilus meningitis
0.035 0.965 0.000
G02.8 Meningitis in other specified infectious and parasitic diseases classified elsewhere
0.035 0.965 0.000
G02.1 Meningitis in mycoses
0.035 0.965 0.000
G02.0 Meningitis in viral diseases classified elsewhere
0.035 0.965 0.000
G03.9 Meningitis, unspecified
0.035 0.965 0.000
G03.8 Meningitis due to other specified causes
0.035 0.965 0.000
G03.2 Benign recurrent meningitis [Mollaret]
0.035 0.965 0.000
G03.1 Chronic meningitis
0.035 0.965 0.000
G03.0 Nonpyogenic meningitis
0.035 0.965 0.000
G05.8 Encephalitis, myelitis and encephalomyelitis in other diseases classified elsewhere
0.035 0.965 0.000
G05.2 Encephalitis, myelitis and encephalomyelitis in other infectious and parasitic diseases classified elsewhere
0.035 0.965 0.000
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere
0.035 0.965 0.000
G05.0 Encephalitis, myelitis and encephalomyelitis in bacterial diseases classified elsewhere
0.035 0.965 0.000
G06.2 Extradural and subdural abscess, unspecified
0.035 0.965 0.000
G06.1 Intraspinal abscess and granuloma
0.035 0.965 0.000
G06.0 Intracranial abscess and granuloma
0.035 0.965 0.000
H54.6 Unqualified visual loss, one eye
0.035 0.965 0.000
H54.5 Low vision, one eye
0.035 0.965 0.000
H54.3 Unqualified visual loss, both eyes
0.035 0.965 0.000
H54.2 Low vision, both eyes
0.035 0.965 0.000
H54.1 Blindness, one eye, low vision, other eye
0.035 0.965 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.035 0.965 0.000
H53.4 Visual field defects
0.035 0.965 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.035 0.965 0.000
Q00-Q07 Congenital malformations of the nervous system
0.035 0.965 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.035 0.965 0.000
H21 Other disorders of iris and ciliary body
0.035 0.965 0.000
G25.9 Extrapyramidal and movement disorder, unspecified
0.035 0.965 0.000
G25.6 Drug-induced tics and other tics of organic origin
0.035 0.965 0.000
G25.5 Other chorea
0.035 0.965 0.000
G25.4 Drug-induced chorea
0.035 0.965 0.000
G25.2 Other specified forms of tremor
0.035 0.965 0.000
G25.1 Drug-induced tremor
0.035 0.965 0.000
M24.0 Loose body in joint
0.035 0.965 0.000
M34.9 Systemic sclerosis, unspecified
0.035 0.965 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.035 0.965 0.000
G70.9 Myoneural disorder, unspecified
0.034 0.965 0.000
G70.8 Other specified myoneural disorders
0.034 0.965 0.000
G70.2 Congenital and developmental myasthenia
0.034 0.965 0.000
G70.1 Toxic myoneural disorders
0.034 0.965 0.000
F99-F99 Unspecified mental disorder
0.035 0.965 0.000
M19.92 Arthrosis, unspecified (Upper arm)
0.035 0.965 0.000
H34 Retinal vascular occlusions
0.035 0.965 0.000
H20 Iridocyclitis
0.034 0.965 0.000
G96.9 Disorder of central nervous system, unspecified
0.034 0.966 0.000
G96.8 Other specified disorders of central nervous system
0.034 0.966 0.000
G96.1 Disorders of meninges, not elsewhere classified
0.034 0.966 0.000
M19.1 Posttraumatic arthrosis of other joints
0.034 0.966 0.000
O47 False labour
0.034 0.966 0.000
M23.1 Discoid meniscus (congenital)
0.034 0.966 0.000
M23.0 Cystic meniscus
0.034 0.966 0.000
H13 Disorders of conjunctiva in diseases classified elsewhere
0.034 0.966 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.034 0.966 0.000
M19.94 Arthrosis, unspecified (Hand)
0.034 0.966 0.000
G25.0 Essential tremor
0.034 0.966 0.000
M24.9 Joint derangement, unspecified
0.034 0.966 0.000
M24.7 Protrusio acetabuli
0.034 0.966 0.000
M24.6 Ankylosis of joint
0.034 0.966 0.000
M24.5 Contracture of joint
0.034 0.966 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.034 0.966 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.034 0.966 0.000
M25.34 Other instability of joint (Hand)
0.034 0.966 0.000
G71.9 Primary disorder of muscle, unspecified
0.033 0.966 0.000
G71.8 Other primary disorders of muscles
0.033 0.966 0.000
G71.3 Mitochondrial myopathy, not elsewhere classified
0.033 0.966 0.000
G71.2 Congenital myopathies
0.033 0.966 0.000
G71.1 Myotonic disorders
0.033 0.966 0.000
G71.0 Muscular dystrophy
0.033 0.966 0.000
G72.9 Myopathy, unspecified
0.033 0.966 0.000
G72.8 Other specified myopathies
0.033 0.966 0.000
G72.4 Inflammatory myopathy, not elsewhere classified
0.033 0.966 0.000
G72.3 Periodic paralysis
0.033 0.966 0.000
G72.2 Myopathy due to other toxic agents
0.033 0.966 0.000
G72.1 Alcoholic myopathy
0.033 0.966 0.000
G72.0 Drug-induced myopathy
0.033 0.966 0.000
G73.7 Myopathy other diseases classified elsewhere
0.033 0.966 0.000
G73.6 Myopathy in metabolic diseases
0.033 0.966 0.000
G73.5 Myopathy in endocrine diseases
0.033 0.966 0.000
G73.4 Myopathy in infectious and parasitic diseases classified elsewhere
0.033 0.966 0.000
G73.3 Myasthenic syndromes in other diseases classified elsewhere
0.033 0.966 0.000
G73.2 Other myasthenic syndromes in neoplastic disease
0.033 0.966 0.000
G73.1 Eaton-Lambert syndrome
0.033 0.966 0.000
G73.0 Myasthenic syndromes in endocrine diseases
0.033 0.966 0.000
M34.1 CR(E)ST syndrome
0.034 0.966 0.000
M19.98 Arthrosis, unspecified (Other)
0.034 0.966 0.000
G97.1 Other reaction to spinal and lumbar puncture
0.033 0.966 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.033 0.966 0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.033 0.966 0.000
M23.37 Other meniscus derangements-Capsular lig
0.033 0.966 0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.033 0.966 0.000
M15 Polyarthrosis
0.033 0.966 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.033 0.966 0.000
M92 Other juvenile osteochondrosis
0.033 0.967 0.000
Q18 Other congenital malformations of face and neck
0.033 0.967 0.000
F60 Specific personality disorders
0.033 0.967 0.000
H50.8 Other specified strabismus
0.033 0.967 0.000
H50.6 Mechanical strabismus
0.033 0.967 0.000
H50.5 Heterophoria
0.033 0.967 0.000
H50.4 Other and unspecified heterotropia
0.033 0.967 0.000
H50.3 Intermittent heterotropia
0.033 0.967 0.000
M21 Other acquired deformities of limbs
0.033 0.967 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.033 0.967 0.000
G63.2 Diabetic polyneuropathy
0.033 0.967 0.000
H11.3 Conjunctival haemorrhage
0.033 0.967 0.000
H18.6 Keratoconus
0.033 0.967 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.033 0.967 0.000
Q35-Q37 Cleft lip and cleft palate
0.033 0.967 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.033 0.967 0.000
M19.8 Other specified arthrosis
0.033 0.967 0.000
M19.2 Other secondary arthrosis
0.033 0.967 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.033 0.967 0.000
F70-F79 Mental retardation
0.033 0.967 0.000
N81.1 Cystocele
0.033 0.967 0.000
G56.2 Lesion of ulnar nerve
0.033 0.967 0.000
H02 Other disorders of eyelid
0.033 0.967 0.000
G63.8 Polyneuropathy in other diseases classified elsewhere
0.032 0.967 0.000
G63.6 Polyneuropathy in other musculoskeletal disorders
0.032 0.967 0.000
G63.5 Polyneuropathy in systemic connective tissue disorders
0.032 0.967 0.000
G63.4 Polyneuropathy in nutritional deficiency
0.032 0.967 0.000
G63.3 Polyneuropathy in other endocrine and metabolic diseases
0.032 0.967 0.000
G63.1 Polyneuropathy in neoplastic disease
0.032 0.967 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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