TreeWAS – Variant ID: rs12304921

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
L82 Seborrhoeic keratosis	0.080	0.920	0.000
Z04.3 Examination and observation following other accident	0.000	0.967	0.033
Z04 Examination and observation for other reasons	0.000	0.986	0.014
Z04.9 Examination and observation for unspecified reason	0.000	0.987	0.013
K85.9 Acute pancreatitis, unspecified	0.012	0.988	0.000
Z04.1 Examination and observation following transport accident	0.000	0.989	0.011
Z04.6 General psychiatric examination, requested by authority	0.000	0.990	0.010
Z04.4 Examination and observation following alleged rape and seduction	0.000	0.990	0.010
Z04.2 Examination and observation following work accident	0.000	0.990	0.010
Z04.0 Blood-alcohol and blood-drug test	0.000	0.990	0.010
M13.94 Arthritis, unspecified (Hand)	0.010	0.990	0.000
Z04.5 Examination and observation following other inflicted injury	0.000	0.991	0.009
M22.4 Chondromalacia patellae	0.009	0.991	0.000
D43.2 Brain, unspecified	0.008	0.992	0.000
D48.1 Connective and other soft tissue	0.008	0.992	0.000
D48.6 Breast	0.008	0.992	0.000
K85 Acute pancreatitis	0.008	0.992	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.007	0.993	0.000
K85.1 Biliary acute pancreatitis	0.007	0.993	0.000
K76.9 Liver disease, unspecified	0.007	0.993	0.000
E05.9 Thyrotoxicosis, unspecified	0.007	0.993	0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.007	0.993	0.000
K76 Other diseases of liver	0.007	0.993	0.000
D48.4 Peritoneum	0.006	0.994	0.000
K76.0 Fatty (change of) liver, not elsewhere classified	0.006	0.994	0.000
K61.0 Anal abscess	0.000	0.994	0.006
T83.0 Mechanical complication of urinary (indwelling) catheter	0.000	0.994	0.006
K85.2 Alcohol-induced acute pancreatitis	0.006	0.994	0.000
K76.8 Other specified diseases of liver	0.006	0.994	0.000
K85.3 Drug-induced acute pancreatitis	0.006	0.994	0.000
K85.0 Idiopathic acute pancreatitis	0.006	0.994	0.000
D48.3 Retroperitoneum	0.005	0.994	0.000
D48.2 Peripheral nerves and autonomic nervous system	0.005	0.994	0.000
D48.0 Bone and articular cartilage	0.006	0.994	0.000
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified	0.005	0.994	0.000
N94.1 Dyspareunia	0.000	0.995	0.005
K70-K77 Diseases of liver	0.005	0.995	0.000
D48.7 Other specified sites	0.005	0.995	0.000
K73 Chronic hepatitis, not elsewhere classified	0.005	0.995	0.000
D43.4 Spinal cord	0.005	0.995	0.000
K85.8 Other acute pancreatitis	0.005	0.995	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.005	0.995	0.000
K08.8 Other specified disorders of teeth and supporting structures	0.000	0.995	0.005
D43.0 Brain, supratentorial	0.005	0.995	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.005	0.995	0.000
D43.9 Central nervous system, unspecified	0.005	0.995	0.000
D43.7 Other parts of central nervous system	0.005	0.995	0.000
D43.3 Cranial nerves	0.005	0.995	0.000
D43.1 Brain, infratentorial	0.005	0.995	0.000
K75 Other inflammatory liver diseases	0.005	0.995	0.000
K76.5 Hepatic veno-occlusive disease	0.005	0.995	0.000
K76.4 Peliosis hepatis	0.005	0.995	0.000
K76.3 Infarction of liver	0.005	0.995	0.000
K76.2 Central haemorrhagic necrosis of liver	0.005	0.995	0.000
K76.1 Chronic passive congestion of liver	0.005	0.995	0.000
D23.1 Skin of eyelid, including canthus	0.005	0.995	0.000
D46 Myelodysplastic syndromes	0.005	0.995	0.000
D46.9 Myelodysplastic syndrome, unspecified	0.005	0.995	0.000
K71 Toxic liver disease	0.005	0.995	0.000
K75.0 Abscess of liver	0.005	0.995	0.000
K74 Fibrosis and cirrhosis of liver	0.005	0.995	0.000
H90.5 Sensorineural hearing loss, unspecified	0.005	0.995	0.000
I31.9 Disease of pericardium, unspecified	0.000	0.996	0.004
H65.9 Nonsuppurative otitis media, unspecified	0.004	0.996	0.000
Z04.8 Examination and observation for other specified reasons	0.000	0.996	0.004
K73.9 Chronic hepatitis, unspecified	0.004	0.996	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.004	0.996	0.000
K74.5 Biliary cirrhosis, unspecified	0.004	0.996	0.000
K76.7 Hepatorenal syndrome	0.004	0.996	0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.004	0.996	0.000
K77 Liver disorders in diseases classified elsewhere	0.004	0.996	0.000
K75.9 Inflammatory liver disease, unspecified	0.004	0.996	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.004	0.996	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.004	0.996	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.004	0.996	0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract	0.004	0.996	0.000
I24.8 Other forms of acute ischaemic heart disease	0.000	0.996	0.004
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.000	0.996	0.004
D37.6 Liver, gallbladder and bile ducts	0.004	0.996	0.000
H65 Nonsuppurative otitis media	0.004	0.996	0.000
L40.5 Arthropathic psoriasis	0.004	0.996	0.000
D37.7 Other digestive organs	0.004	0.996	0.000
K75.4 Autoimmune hepatitis	0.004	0.996	0.000
D46.7 Other myelodysplastic syndromes	0.004	0.996	0.000
K71.1 Toxic liver disease with hepatic necrosis	0.004	0.996	0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.004	0.996	0.000
K71.0 Toxic liver disease with cholestasis	0.004	0.996	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.004	0.996	0.000
K75.2 Nonspecific reactive hepatitis	0.004	0.996	0.000
K75.1 Phlebitis of portal vein	0.004	0.996	0.000
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality	0.004	0.996	0.000
D46.5 Refractory anaemia with multi-lineage dysplasia	0.004	0.996	0.000
D46.4 Refractory anaemia, unspecified	0.004	0.996	0.000
D46.3 Refractory anaemia with excess of blasts with transformation	0.004	0.996	0.000
D46.1 Refractory anaemia with sideroblasts	0.004	0.996	0.000
D46.0 Refractory anaemia without sideroblasts, so stated	0.004	0.996	0.000
K74.3 Primary biliary cirrhosis	0.004	0.996	0.000
D37.9 Digestive organ, unspecified	0.004	0.996	0.000
D46.2 Refractory anaemia with excess of blasts	0.004	0.996	0.000
D48.5 Skin	0.004	0.996	0.000
H65.2 Chronic serous otitis media	0.004	0.996	0.000
H65.4 Other chronic nonsuppurative otitis media	0.004	0.996	0.000
I44.2 Atrioventricular block, complete	0.000	0.996	0.004
D38.5 Other respiratory organs	0.004	0.996	0.000
K72 Hepatic failure, not elsewhere classified	0.004	0.996	0.000
K71.9 Toxic liver disease, unspecified	0.003	0.996	0.000
K71.8 Toxic liver disease with other disorders of liver	0.003	0.996	0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.003	0.996	0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.003	0.996	0.000
K71.5 Toxic liver disease with chronic active hepatitis	0.003	0.996	0.000
K71.4 Toxic liver disease with chronic lobular hepatitis	0.003	0.996	0.000
K71.3 Toxic liver disease with chronic persistent hepatitis	0.003	0.996	0.000
K71.2 Toxic liver disease with acute hepatitis	0.003	0.996	0.000
B97.7 Papillomavirus as the cause of diseases classified to other chapters	0.000	0.996	0.004
D37.3 Appendix	0.003	0.996	0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.003	0.996	0.000
K74.4 Secondary biliary cirrhosis	0.003	0.996	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.003	0.996	0.000
K74.1 Hepatic sclerosis	0.003	0.996	0.000
L40 Psoriasis	0.004	0.996	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.003	0.996	0.000
L40.8 Other psoriasis	0.003	0.997	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.003	0.997	0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation	0.003	0.997	0.000
E21.3 Hyperparathyroidism, unspecified	0.003	0.997	0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified	0.003	0.997	0.000
D37.4 Colon	0.003	0.997	0.000
D12.3 Transverse colon	0.000	0.997	0.003
H65.3 Chronic mucoid otitis media	0.003	0.997	0.000
D68.8 Other specified coagulation defects	0.000	0.997	0.003
K75.8 Other specified inflammatory liver diseases	0.003	0.997	0.000
D38.6 Respiratory organ, unspecified	0.003	0.997	0.000
D38.4 Thymus	0.003	0.997	0.000
D38.3 Mediastinum	0.003	0.997	0.000
D38.2 Pleura	0.003	0.997	0.000
D38.0 Larynx	0.003	0.997	0.000
L93.0 Discoid lupus erythematosus	0.003	0.997	0.000
K77.8 Liver disorders in other diseases classified elsewhere	0.003	0.997	0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.003	0.997	0.000
L40.9 Psoriasis, unspecified	0.003	0.997	0.000
K70 Alcoholic liver disease	0.003	0.997	0.000
M94.86 Other specified disorders of cartilage (Lower leg)	0.003	0.997	0.000
D37.0 Lip, oral cavity and pharynx	0.003	0.997	0.000
D47.2 Monoclonal gammopathy	0.003	0.997	0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.003	0.997	0.000
H65.1 Other acute nonsuppurative otitis media	0.003	0.997	0.000
H65.0 Acute serous otitis media	0.003	0.997	0.000
D37.2 Small intestine	0.003	0.997	0.000
K70.9 Alcoholic liver disease, unspecified	0.003	0.997	0.000
D38.1 Trachea, bronchus and lung	0.003	0.997	0.000
D42.9 Meninges, unspecified	0.003	0.997	0.000
D42.1 Spinal meninges	0.003	0.997	0.000
D42.0 Cerebral meninges	0.003	0.997	0.000
G12.2 Motor neuron disease	0.000	0.997	0.003
K74.0 Hepatic fibrosis	0.003	0.997	0.000
H73.8 Other specified disorders of tympanic membrane	0.003	0.997	0.000
K72.9 Hepatic failure, unspecified	0.003	0.997	0.000
K74.6 Other and unspecified cirrhosis of liver	0.003	0.997	0.000
S00.8 Superficial injury of other parts of head	0.000	0.997	0.003
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.003	0.997	0.000
L93 Lupus erythematosus	0.003	0.997	0.000
D40.0 Prostate	0.003	0.997	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.003	0.997	0.000
K72.1 Chronic hepatic failure	0.003	0.997	0.000
H90 Conductive and sensorineural hearing loss	0.003	0.997	0.000
D37.1 Stomach	0.003	0.997	0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.003	0.997	0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.003	0.997	0.000
D40.9 Male genital organ, unspecified	0.003	0.997	0.000
D40.7 Other male genital organs	0.003	0.997	0.000
M22 Disorders of patella	0.003	0.997	0.000
L40.4 Guttate psoriasis	0.003	0.997	0.000
L40.3 Pustulosis palmaris et plantaris	0.003	0.997	0.000
L40.2 Acrodermatitis continua	0.003	0.997	0.000
L40.1 Generalised pustular psoriasis	0.003	0.997	0.000
L80-L99 Other disorders of the skin and subcutaneous tissue	0.003	0.997	0.000
E26.9 Hyperaldosteronism, unspecified	0.003	0.997	0.000
M47.82 Other spondylosis (Cervical region)	0.003	0.997	0.000
R59.9 Enlarged lymph nodes, unspecified	0.003	0.997	0.000
E23.7 Disorder of pituitary gland, unspecified	0.003	0.997	0.000
E26 Hyperaldosteronism	0.003	0.997	0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.003	0.997	0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.003	0.997	0.000
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.003	0.997	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.003	0.997	0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue	0.003	0.997	0.000
Z74.0 Reduced mobility	0.003	0.997	0.000
K08 Other disorders of teeth and supporting structures	0.000	0.997	0.003
T83.1 Mechanical complication of other urinary devices and implants	0.000	0.997	0.003
K25.4 Chronic or unspecified with haemorrhage	0.000	0.997	0.003
G59.0 Diabetic mononeuropathy	0.003	0.997	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.003	0.997	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.003	0.997	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.000	0.997	0.003
E21.5 Disorder of parathyroid gland, unspecified	0.003	0.997	0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.003	0.997	0.000
L88 Pyoderma gangrenosum	0.003	0.997	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.003	0.997	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.003	0.997	0.000
E23 Hypofunction and other disorders of pituitary gland	0.003	0.997	0.000
L92 Granulomatous disorders of skin and subcutaneous tissue	0.003	0.997	0.000
C50.4 Upper-outer quadrant of breast	0.003	0.997	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.002	0.997	0.000
L40.0 Psoriasis vulgaris	0.002	0.997	0.000
D44.9 Endocrine gland, unspecified	0.002	0.997	0.000
D44.8 Pluriglandular involvement	0.002	0.997	0.000
D44.7 Aortic body and other paraganglia	0.002	0.997	0.000
D44.6 Carotid body	0.002	0.997	0.000
D44.5 Pineal gland	0.002	0.997	0.000
D44.2 Parathyroid gland	0.002	0.997	0.000
D44.0 Thyroid gland	0.002	0.997	0.000
E26.0 Primary hyperaldosteronism	0.002	0.997	0.000
L95 Vasculitis limited to skin, not elsewhere classified	0.002	0.997	0.000
E20-E35 Disorders of other endocrine glands	0.003	0.997	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.002	0.997	0.000
L95.9 Vasculitis limited to skin, unspecified	0.002	0.997	0.000
H90.3 Sensorineural hearing loss, bilateral	0.002	0.998	0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.000	0.998	0.002
M94.8 Other specified disorders of cartilage	0.002	0.998	0.000
D89.1 Cryoglobulinaemia	0.002	0.998	0.000
K76.6 Portal hypertension	0.002	0.998	0.000
L84 Corns and callosities	0.002	0.998	0.000
E23.2 Diabetes insipidus	0.002	0.998	0.000
K70.4 Alcoholic hepatic failure	0.002	0.998	0.000
L93.2 Other local lupus erythematosus	0.002	0.998	0.000
L93.1 Subacute cutaneous lupus erythematosus	0.002	0.998	0.000
M22.0 Recurrent dislocation of patella	0.002	0.998	0.000
E27 Other disorders of adrenal gland	0.002	0.998	0.000
D44.1 Adrenal gland	0.002	0.998	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.002	0.998	0.000
H73 Other disorders of tympanic membrane	0.002	0.998	0.000
E05.8 Other thyrotoxicosis	0.002	0.998	0.000
E21.4 Other specified disorders of parathyroid gland	0.002	0.998	0.000
E21.2 Other hyperparathyroidism	0.002	0.998	0.000
D47.3 Essential (haemorrhagic) thrombocythaemia	0.002	0.998	0.000
K08.1 Loss of teeth due to accident, extraction or local periodontal disease	0.000	0.998	0.002
D45 Polycythaemia vera	0.002	0.998	0.000
D44.4 Craniopharyngeal duct	0.002	0.998	0.000
M22.3 Other derangements of patella	0.002	0.998	0.000
D39.9 Female genital organ, unspecified	0.002	0.998	0.000
D39.7 Other female genital organs	0.002	0.998	0.000
D39.2 Placenta	0.002	0.998	0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified	0.002	0.998	0.000
D41.9 Urinary organ, unspecified	0.002	0.998	0.000
D41.7 Other urinary organs	0.002	0.998	0.000
D41.3 Urethra	0.002	0.998	0.000
D41.2 Ureter	0.002	0.998	0.000
D41.1 Renal pelvis	0.002	0.998	0.000
R93 Abnormal findings on diagnostic imaging of other body structures	0.002	0.998	0.000
D37.5 Rectum	0.002	0.998	0.000
D40.1 Testis	0.002	0.998	0.000
K08.2 Atrophy of edentulous alveolar ridge	0.000	0.998	0.002
M22.1 Recurrent subluxation of patella	0.002	0.998	0.000
M22.9 Disorder of patella, unspecified	0.002	0.998	0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.002	0.998	0.000
L87 Transepidermal elimination disorders	0.002	0.998	0.000
L86 Keratoderma in diseases classified elsewhere	0.002	0.998	0.000
E27.9 Disorder of adrenal gland, unspecified	0.002	0.998	0.000
E26.8 Other hyperaldosteronism	0.002	0.998	0.000
E26.1 Secondary hyperaldosteronism	0.002	0.998	0.000
K70.0 Alcoholic fatty liver	0.002	0.998	0.000
E27.1 Primary adrenocortical insufficiency	0.002	0.998	0.000
K08.0 Exfoliation of teeth due to systemic causes	0.000	0.998	0.002
D44.3 Pituitary gland	0.002	0.998	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.002	0.998	0.000
M51.8 Other specified intervertebral disk disorders	0.002	0.998	0.000
D47.4 Osteomyelofibrosis	0.002	0.998	0.000
E24 Cushing's syndrome	0.002	0.998	0.000
M94.85 Other specified disorders of cartilage (Pelvic region and thigh)	0.002	0.998	0.000
F32.1 Moderate depressive episode	0.002	0.998	0.000
K70.3 Alcoholic cirrhosis of liver	0.002	0.998	0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]	0.000	0.998	0.002
E05.5 Thyroid crisis or storm	0.002	0.998	0.000
E05.4 Thyrotoxicosis factitia	0.002	0.998	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.002	0.998	0.000
K08.9 Disorder of teeth and supporting structures, unspecified	0.000	0.998	0.002
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.000	0.998	0.002
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.002	0.998	0.000
D89.3 Immune reconstitution syndrome	0.002	0.998	0.000
K08.3 Retained dental root	0.000	0.998	0.002
T83.2 Mechanical complication of graft of urinary organ	0.000	0.998	0.002
D39.0 Uterus	0.002	0.998	0.000
E27.2 Addisonian crisis	0.002	0.998	0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.002	0.998	0.000
M94.88 Other specified disorders of cartilage (Other)	0.002	0.998	0.000
D47.1 Chronic myeloproliferative disease	0.002	0.998	0.000
K59.8 Other specified functional intestinal disorders	0.002	0.998	0.000
L80 Vitiligo	0.002	0.998	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.002	0.998	0.000
E23.1 Drug-induced hypopituitarism	0.002	0.998	0.000
L92.2 Granuloma faciale [eosinophilic granuloma of skin]	0.002	0.998	0.000
L92.1 Necrobiosis lipoidica, not elsewhere classified	0.002	0.998	0.000
Q43.0 Meckel's diverticulum	0.002	0.998	0.000
E20 Hypoparathyroidism	0.002	0.998	0.000
I44.6 Other and unspecified fascicular block	0.000	0.998	0.002
L95.1 Erythema elevatum diutinum	0.002	0.998	0.000
L95.0 Livedoid vasculitis	0.002	0.998	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.002	0.998	0.000
E32 Diseases of thymus	0.002	0.998	0.000
E31 Polyglandular dysfunction	0.002	0.998	0.000
E30 Disorders of puberty, not elsewhere classified	0.002	0.998	0.000
E25 Adrenogenital disorders	0.002	0.998	0.000
M13.00 Polyarthritis, unspecified (Multiple sites)	0.002	0.998	0.000
E24.0 Pituitary-dependent Cushing's disease	0.002	0.998	0.000
M13.90 Arthritis, unspecified (Multiple sites)	0.002	0.998	0.000
E29 Testicular dysfunction	0.002	0.998	0.000
M94.89 Other specified disorders of cartilage (Site unspecified)	0.002	0.998	0.000
M94.87 Other specified disorders of cartilage (Ankle and foot)	0.002	0.998	0.000
M94.84 Other specified disorders of cartilage (Hand)	0.002	0.998	0.000
M94.83 Other specified disorders of cartilage (Forearm)	0.002	0.998	0.000
M94.82 Other specified disorders of cartilage (Upper arm)	0.002	0.998	0.000
M94.81 Other specified disorders of cartilage (Shoulder region)	0.002	0.998	0.000
M94.80 Other specified disorders of cartilage (Multiple sites)	0.002	0.998	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.002	0.998	0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.002	0.998	0.000
E27.5 Adrenomedullary hyperfunction	0.002	0.998	0.000
E27.0 Other adrenocortical overactivity	0.002	0.998	0.000
K72.0 Acute and subacute hepatic failure	0.002	0.998	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.002	0.998	0.000
H73.1 Chronic myringitis	0.002	0.998	0.000
H73.0 Acute myringitis	0.002	0.998	0.000
E28 Ovarian dysfunction	0.002	0.998	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.002	0.998	0.000
E34 Other endocrine disorders	0.002	0.998	0.000
D68.6 Other Thrombophilia	0.000	0.998	0.002
K46.9 Unspecified abdominal hernia without obstruction or gangrene	0.002	0.998	0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.000	0.998	0.002
E23.6 Other disorders of pituitary gland	0.002	0.998	0.000
H90-H95 Other disorders of ear	0.002	0.998	0.000
M13.09 Polyarthritis, unspecified (Site unspecified)	0.002	0.998	0.000
M22.10 Recurrent subluxation of patella, unspecified knee	0.002	0.998	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.002	0.998	0.000
L87.9 Transepidermal elimination disorder, unspecified	0.002	0.998	0.000
L87.8 Other transepidermal elimination disorders	0.002	0.998	0.000
L87.2 Elastosis perforans serpiginosa	0.002	0.998	0.000
L87.1 Reactive perforating collagenosis	0.002	0.998	0.000
L87.0 Keratosis follicularis et parafollicularis in cutem penetrans [Kyrle]	0.002	0.998	0.000
L95.8 Other vasculitis limited to skin	0.002	0.998	0.000
L99.8 Other specified disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.002	0.998	0.000
L99.0 Amyloidosis of skin	0.002	0.998	0.000
R93.6 Abnormal findings on diagnostic imaging of limbs	0.002	0.998	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.002	0.998	0.000
L42 Pityriasis rosea	0.002	0.998	0.000
L40-L45 Papulosquamous disorders	0.002	0.998	0.000
E34.8 Other specified endocrine disorders	0.002	0.998	0.000
L92.8 Other granulomatous disorders of skin and subcutaneous tissue	0.002	0.998	0.000
M22.2 Patellofemoral disorders	0.002	0.998	0.000
L83 Acanthosis nigricans	0.002	0.998	0.000
H61.8 Other specified disorders of external ear	0.002	0.998	0.000
G35 Multiple sclerosis	0.000	0.998	0.002
M40.56 Lordosis, unspecified (Lumbar region)	0.002	0.998	0.000
E24.8 Other Cushing's syndrome	0.002	0.998	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.002	0.998	0.000
E24.3 Ectopic ACTH syndrome	0.002	0.998	0.000
E24.1 Nelson's syndrome	0.002	0.998	0.000
K70.1 Alcoholic hepatitis	0.002	0.998	0.000
M72.08 Palmar fascial fibromatosis [Dupuytren]-Other	0.000	0.998	0.002
M72.07 Palmar fascial fibromatosis [Dupuytren]-Ankle/Foot	0.000	0.998	0.002
M72.06 Palmar fascial fibromatosis [Dupuytren]-Lower Leg	0.000	0.998	0.002
M72.05 Palmar fascial fibromatosis [Dupuytren]-Pelvic/Thigh	0.000	0.998	0.002
M72.03 Palmar fascial fibromatosis [Dupuytren]-Forearm	0.000	0.998	0.002
M72.02 Palmar fascial fibromatosis [Dupuytren]-Upper arm	0.000	0.998	0.002
M72.01 Palmar fascial fibromatosis [Dupuytren]-Shldr region	0.000	0.998	0.002
M72.00 Palmar fascial fibromatosis [Dupuytren]-Mult sites	0.000	0.998	0.002
D41.0 Kidney	0.002	0.998	0.000
K11.2 Sialoadenitis	0.000	0.998	0.002
M13.0 Polyarthritis, unspecified	0.002	0.998	0.000
T83.3 Mechanical complication of intra-uterine contraceptive device	0.000	0.998	0.002
D68 Other coagulation defects	0.000	0.998	0.002
M07.30 Other psoriatic arthropathies (Multiple sites)	0.002	0.998	0.000
L91 Hypertrophic disorders of skin	0.002	0.998	0.000
H65-H75 Diseases of middle ear and mastoid	0.002	0.998	0.000
E24.9 Cushing's syndrome, unspecified	0.002	0.998	0.000
E24.2 Drug-induced Cushing's syndrome	0.002	0.998	0.000
H59.8 Other postprocedural disorders of eye and adnexa	0.000	0.998	0.002
H93 Other disorders of ear, not elsewhere classified	0.002	0.998	0.000
M72.09 Palmar fascial fibromatosis [Dupuytren]-Site unspec	0.000	0.998	0.002
E20.8 Other hypoparathyroidism	0.002	0.998	0.000
E20.1 Pseudohypoparathyroidism	0.002	0.998	0.000
E20.0 Idiopathic hypoparathyroidism	0.002	0.998	0.000
E23.0 Hypopituitarism	0.002	0.998	0.000
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system	0.002	0.998	0.000
G12 Spinal muscular atrophy and related syndromes	0.000	0.998	0.002
K61 Abscess of anal and rectal regions	0.000	0.998	0.002
L94 Other localised connective tissue disorders	0.002	0.998	0.000
L85 Other epidermal thickening	0.002	0.998	0.000
M43.02 Spondylolysis (Cervical region)	0.002	0.998	0.000
E20.9 Hypoparathyroidism, unspecified	0.002	0.998	0.000
E25.9 Adrenogenital disorder, unspecified	0.002	0.998	0.000
E25.8 Other adrenogenital disorders	0.002	0.998	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.002	0.998	0.000
E30.9 Disorder of puberty, unspecified	0.002	0.998	0.000
E30.8 Other disorders of puberty	0.002	0.998	0.000
E30.1 Precocious puberty	0.002	0.998	0.000
E30.0 Delayed puberty	0.002	0.998	0.000
E31.9 Polyglandular dysfunction, unspecified	0.002	0.998	0.000
E31.8 Other polyglandular dysfunction	0.002	0.998	0.000
E31.1 Polyglandular hyperfunction	0.002	0.998	0.000
E31.0 Autoimmune polyglandular failure	0.002	0.998	0.000
E32.9 Disease of thymus, unspecified	0.002	0.998	0.000
E32.8 Other diseases of thymus	0.002	0.998	0.000
E32.1 Abscess of thymus	0.002	0.998	0.000
E32.0 Persistent hyperplasia of thymus	0.002	0.998	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.002	0.998	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.002	0.998	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.002	0.998	0.000
L50.0 Allergic urticaria	0.002	0.998	0.000
M07.3 Other psoriatic arthropathies	0.002	0.998	0.000
D68.9 Coagulation defect, unspecified	0.000	0.998	0.002
G95.8 Other specified diseases of spinal cord	0.000	0.998	0.002
H60.5 Acute otitis externa, non-infective	0.002	0.998	0.000
M22.8 Other disorders of patella	0.002	0.998	0.000
W19.2 School, other institution and public administrative area	0.002	0.998	0.000
M43.09 Spondylolysis (Site unspecified)	0.002	0.998	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.002	0.998	0.000
E28.3 Primary ovarian failure	0.002	0.998	0.000
I51.6 Cardiovascular disease, unspecified	0.002	0.998	0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.000	0.998	0.002
L52 Erythema nodosum	0.002	0.998	0.000
E29.9 Testicular dysfunction, unspecified	0.002	0.998	0.000
E29.8 Other testicular dysfunction	0.002	0.998	0.000
E29.0 Testicular hyperfunction	0.002	0.998	0.000
H70 Mastoiditis and related conditions	0.002	0.998	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.000	0.998	0.002
D41.4 Bladder	0.002	0.998	0.000
E28.9 Ovarian dysfunction, unspecified	0.002	0.998	0.000
E28.8 Other ovarian dysfunction	0.002	0.998	0.000
E28.1 Androgen excess	0.002	0.998	0.000
E28.0 Oestrogen excess	0.002	0.998	0.000
M85.8 Other specified disorders of bone density and structure	0.002	0.998	0.000
H60-H62 Diseases of external ear	0.002	0.998	0.000
E27.8 Other specified disorders of adrenal gland	0.002	0.998	0.000
E34.5 Androgen resistance syndrome	0.001	0.998	0.000
E34.4 Constitutional tall stature	0.001	0.998	0.000
E34.3 Short stature, not elsewhere classified	0.001	0.998	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.001	0.998	0.000
E34.1 Other hypersecretion of intestinal hormones	0.001	0.998	0.000
H93.1 Tinnitus	0.002	0.998	0.000
N18.2 Chronic kidney disease, stage 2	0.000	0.998	0.002
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.000	0.998	0.002
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters	0.000	0.998	0.002
L50.1 Idiopathic urticaria	0.002	0.998	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.002	0.998	0.000
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.002	0.998	0.000
D12.0 Caecum	0.000	0.998	0.002
H70.9 Mastoiditis, unspecified	0.002	0.998	0.000
H90.0 Conductive hearing loss, bilateral	0.001	0.998	0.000
H60 Otitis externa	0.002	0.998	0.000
I44 Atrioventricular and left bundle-branch block	0.000	0.998	0.002
L44 Other papulosquamous disorders	0.002	0.998	0.000
L41 Parapsoriasis	0.002	0.998	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.002	0.998	0.000
D68.5 Primary Thrombophilia	0.000	0.998	0.002
H35.9 Retinal disorder, unspecified	0.002	0.998	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.002	0.998	0.000
E29.1 Testicular hypofunction	0.002	0.998	0.000
H93.8 Other specified disorders of ear	0.002	0.998	0.000
I44.1 Atrioventricular block, second degree	0.000	0.998	0.002
N94.4 Primary dysmenorrhoea	0.000	0.998	0.002
M13.08 Polyarthritis, unspecified (Other)	0.001	0.998	0.000
M13.07 Polyarthritis, unspecified (Ankle and foot)	0.001	0.998	0.000
M13.06 Polyarthritis, unspecified (Lower leg)	0.001	0.998	0.000
M13.05 Polyarthritis, unspecified (Pelvic region and thigh)	0.001	0.998	0.000
M13.04 Polyarthritis, unspecified (Hand)	0.001	0.998	0.000
M13.03 Polyarthritis, unspecified (Forearm)	0.001	0.998	0.000
M13.02 Polyarthritis, unspecified (Upper arm)	0.001	0.998	0.000
M13.01 Polyarthritis, unspecified (Shoulder region)	0.001	0.998	0.000
D68.4 Acquired coagulation factor deficiency	0.000	0.998	0.001
K61.1 Rectal abscess	0.000	0.998	0.002
L91.9 Hypertrophic disorder of skin, unspecified	0.001	0.998	0.000
L92.0 Granuloma annulare	0.001	0.998	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.001	0.998	0.000
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.001	0.998	0.000
D39.1 Ovary	0.001	0.998	0.001
R94.4 Abnormal results of kidney function studies	0.002	0.998	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.001	0.998	0.000
H68 Eustachian salpingitis and obstruction	0.001	0.998	0.000
H67 Otitis media in diseases classified elsewhere	0.001	0.998	0.000
H92 Otalgia and effusion of ear	0.002	0.998	0.000
Chapter VIII Diseases of the ear and mastoid process	0.002	0.998	0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.001	0.998	0.000
H93.3 Disorders of acoustic nerve	0.001	0.998	0.000
H93.2 Other abnormal auditory perceptions	0.001	0.998	0.000
H93.0 Degenerative and vascular disorders of ear	0.001	0.998	0.000
M43.0 Spondylolysis	0.002	0.998	0.000
V89.2 Person injured in unspecified motor-vehicle accident, traffic	0.000	0.998	0.002
M43.06 Spondylolysis (Lumbar region)	0.001	0.998	0.000
E34.0 Carcinoid syndrome	0.001	0.998	0.000
G12.9 Spinal muscular atrophy, unspecified	0.000	0.998	0.001
G12.8 Other spinal muscular atrophies and related syndromes	0.000	0.998	0.001
G12.1 Other inherited spinal muscular atrophy	0.000	0.998	0.001
G12.0 Infantile spinal muscular atrophy, type I [Werdnig-Hoffman]	0.000	0.998	0.001
H61.9 Disorder of external ear, unspecified	0.002	0.998	0.000
K61.2 Anorectal abscess	0.000	0.998	0.001
L85.3 Xerosis cutis	0.001	0.998	0.000
L85.2 Keratosis punctata (palmaris et plantaris)	0.001	0.998	0.000
L85.0 Acquired ichthyosis	0.001	0.998	0.000
L94.8 Other specified localised connective tissue disorders	0.001	0.998	0.000
L94.6 Ainhum	0.001	0.998	0.000
L94.5 Poikiloderma vasculare atrophicans	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations