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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12342373
log Bayes Factor = 0.0855483
Chromosome 9   position 129,402,567  (GRCh37) Explore rs12342373 on Ensembl!
Variant rs12342373 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E11.3 With ophthalmic complications
0.000 0.873 0.127
E11 Non-insulin-dependent diabetes mellitus
0.000 0.873 0.127
E11.2 With renal complications
0.000 0.875 0.125
E11.4 With neurological complications
0.000 0.885 0.115
E11.6 With other specified complications
0.000 0.890 0.110
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.890 0.110
E10-E14 Diabetes mellitus
0.000 0.891 0.109
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.892 0.108
E05.9 Thyrotoxicosis, unspecified
0.000 0.893 0.107
E00-E07 Disorders of thyroid gland
0.000 0.895 0.105
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.896 0.104
E11.1 With ketoacidosis
0.000 0.900 0.100
E20-E35 Disorders of other endocrine glands
0.000 0.902 0.098
E27 Other disorders of adrenal gland
0.000 0.905 0.095
E11.7 With multiple complications
0.000 0.909 0.091
E11.8 With unspecified complications
0.000 0.913 0.087
E50-E64 Other nutritional deficiencies
0.000 0.913 0.086
E28 Ovarian dysfunction
0.000 0.914 0.086
E27.1 Primary adrenocortical insufficiency
0.000 0.915 0.085
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.917 0.083
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.917 0.083
E13 Other specified diabetes mellitus
0.000 0.919 0.081
E05.5 Thyroid crisis or storm
0.000 0.921 0.079
E05.4 Thyrotoxicosis factitia
0.000 0.921 0.079
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.921 0.079
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.921 0.079
E53 Deficiency of other B group vitamins
0.000 0.921 0.079
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.921 0.079
E12 Malnutrition-related diabetes mellitus
0.000 0.921 0.078
E04 Other non-toxic goitre
0.000 0.922 0.078
E28.2 Polycystic ovarian syndrome
0.000 0.922 0.078
E27.8 Other specified disorders of adrenal gland
0.000 0.923 0.077
E22 Hyperfunction of pituitary gland
0.000 0.924 0.076
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.925 0.075
E00 Congenital iodine-deficiency syndrome
0.000 0.925 0.075
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.925 0.075
E27.9 Disorder of adrenal gland, unspecified
0.000 0.925 0.075
E24 Cushing's syndrome
0.000 0.926 0.074
E53.8 Deficiency of other specified B group vitamins
0.000 0.926 0.074
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.927 0.072
E04.9 Non-toxic goitre, unspecified
0.000 0.928 0.072
E05.8 Other thyrotoxicosis
0.000 0.928 0.071
E03 Other hypothyroidism
0.000 0.929 0.071
E11.5 With peripheral circulatory complications
0.000 0.929 0.071
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.929 0.070
E32 Diseases of thymus
0.000 0.929 0.070
E31 Polyglandular dysfunction
0.000 0.929 0.070
E30 Disorders of puberty, not elsewhere classified
0.000 0.929 0.070
E25 Adrenogenital disorders
0.000 0.929 0.070
E10 Insulin-dependent diabetes mellitus
0.000 0.930 0.070
E20 Hypoparathyroidism
0.000 0.931 0.069
E27.5 Adrenomedullary hyperfunction
0.000 0.931 0.069
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.931 0.069
E27.2 Addisonian crisis
0.000 0.931 0.069
E27.0 Other adrenocortical overactivity
0.000 0.931 0.069
E40-E46 Malnutrition
0.000 0.931 0.069
E65-E68 Obesity and other hyperalimentation
0.000 0.932 0.068
E07 Other disorders of thyroid
0.000 0.933 0.067
E11.0 With coma
0.000 0.934 0.065
E23 Hypofunction and other disorders of pituitary gland
0.000 0.934 0.065
E06 Thyroiditis
0.000 0.936 0.064
E26 Hyperaldosteronism
0.000 0.936 0.064
E10.3 With ophthalmic complications
0.000 0.936 0.064
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.938 0.062
E63 Other nutritional deficiencies
0.000 0.938 0.062
E56 Other vitamin deficiencies
0.000 0.938 0.062
E51 Thiamine deficiency
0.000 0.938 0.062
E50 Vitamin A deficiency
0.000 0.938 0.062
E60 Dietary zinc deficiency
0.000 0.938 0.062
E59 Dietary selenium deficiency
0.000 0.938 0.062
E58 Dietary calcium deficiency
0.000 0.938 0.062
E54 Ascorbic acid deficiency
0.000 0.938 0.062
E52 Niacin deficiency [pellagra]
0.000 0.938 0.062
E28.9 Ovarian dysfunction, unspecified
0.000 0.938 0.062
E28.8 Other ovarian dysfunction
0.000 0.938 0.062
E28.1 Androgen excess
0.000 0.938 0.062
E28.0 Oestrogen excess
0.000 0.938 0.062
E21.0 Primary hyperparathyroidism
0.000 0.939 0.061
E13.9 Without complications
0.000 0.939 0.061
E16 Other disorders of pancreatic internal secretion
0.000 0.939 0.061
E28.3 Primary ovarian failure
0.000 0.940 0.060
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.941 0.059
E04.2 Non-toxic multinodular goitre
0.000 0.941 0.059
E13.8 With unspecified complications
0.000 0.942 0.058
E13.7 With multiple complications
0.000 0.942 0.058
E13.6 With other specified complications
0.000 0.942 0.058
E13.5 With peripheral circulatory complications
0.000 0.942 0.058
E13.4 With neurological complications
0.000 0.942 0.058
E13.3 With ophthalmic complications
0.000 0.942 0.058
E13.2 With renal complications
0.000 0.942 0.058
E13.1 With ketoacidosis
0.000 0.942 0.058
E13.0 With coma
0.000 0.942 0.058
E10.2 With renal complications
0.000 0.942 0.058
E55 Vitamin D deficiency
0.000 0.942 0.058
E24.9 Cushing's syndrome, unspecified
0.000 0.943 0.057
E22.1 Hyperprolactinaemia
0.000 0.943 0.057
E53.9 Vitamin B deficiency, unspecified
0.000 0.943 0.057
E53.1 Pyridoxine deficiency
0.000 0.943 0.057
E53.0 Riboflavin deficiency
0.000 0.943 0.057
E15 Nondiabetic hypoglycaemic coma
0.000 0.943 0.057
E12.9 Without complications
0.000 0.943 0.056
E12.8 With unspecified complications
0.000 0.943 0.056
E12.7 With multiple complications
0.000 0.943 0.056
E12.6 With other specified complications
0.000 0.943 0.056
E12.5 With peripheral circulatory complications
0.000 0.943 0.056
E12.4 With neurological complications
0.000 0.943 0.056
E12.3 With ophthalmic complications
0.000 0.943 0.056
E12.2 With renal complications
0.000 0.943 0.056
E12.1 With ketoacidosis
0.000 0.943 0.056
E12.0 With coma
0.000 0.943 0.056
E04.8 Other specified non-toxic goitre
0.000 0.943 0.056
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.945 0.054
E22.8 Other hyperfunction of pituitary gland
0.000 0.945 0.054
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.946 0.054
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.946 0.054
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.946 0.054
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.946 0.054
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.946 0.054
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.946 0.054
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.946 0.054
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.946 0.054
E24.8 Other Cushing's syndrome
0.000 0.946 0.053
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.946 0.053
E24.3 Ectopic ACTH syndrome
0.000 0.946 0.053
E24.2 Drug-induced Cushing's syndrome
0.000 0.946 0.053
E24.1 Nelson's syndrome
0.000 0.946 0.053
E24.0 Pituitary-dependent Cushing's disease
0.000 0.946 0.053
E04.0 Non-toxic diffuse goitre
0.000 0.947 0.053
E61 Deficiency of other nutrient elements
0.000 0.947 0.053
E23.2 Diabetes insipidus
0.000 0.947 0.053
E34 Other endocrine disorders
0.000 0.947 0.052
E14 Unspecified diabetes mellitus
0.000 0.947 0.053
E22.0 Acromegaly and pituitary gigantism
0.000 0.948 0.052
E29 Testicular dysfunction
0.000 0.948 0.052
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.948 0.052
E21.4 Other specified disorders of parathyroid gland
0.000 0.948 0.052
E21.2 Other hyperparathyroidism
0.000 0.948 0.052
E03.5 Myxoedema coma
0.000 0.949 0.051
E03.4 Atrophy of thyroid (acquired)
0.000 0.949 0.051
E03.3 Postinfectious hypothyroidism
0.000 0.949 0.051
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.949 0.051
E03.1 Congenital hypothyroidism without goitre
0.000 0.949 0.051
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.949 0.051
E16.2 Hypoglycaemia, unspecified
0.000 0.949 0.051
E03.8 Other specified hypothyroidism
0.000 0.949 0.051
E25.9 Adrenogenital disorder, unspecified
0.000 0.949 0.051
E25.8 Other adrenogenital disorders
0.000 0.949 0.051
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.949 0.051
E30.9 Disorder of puberty, unspecified
0.000 0.949 0.051
E30.8 Other disorders of puberty
0.000 0.949 0.051
E30.1 Precocious puberty
0.000 0.949 0.051
E30.0 Delayed puberty
0.000 0.949 0.051
E31.9 Polyglandular dysfunction, unspecified
0.000 0.949 0.051
E31.8 Other polyglandular dysfunction
0.000 0.949 0.051
E31.1 Polyglandular hyperfunction
0.000 0.949 0.051
E31.0 Autoimmune polyglandular failure
0.000 0.949 0.051
E32.9 Disease of thymus, unspecified
0.000 0.949 0.051
E32.8 Other diseases of thymus
0.000 0.949 0.051
E32.1 Abscess of thymus
0.000 0.949 0.051
E32.0 Persistent hyperplasia of thymus
0.000 0.949 0.051
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.949 0.051
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.949 0.051
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.949 0.051
E10.7 With multiple complications
0.000 0.949 0.050
E10.6 With other specified complications
0.000 0.949 0.050
E10.0 With coma
0.000 0.949 0.050
E66 Obesity
0.000 0.950 0.050
E20.8 Other hypoparathyroidism
0.000 0.950 0.049
E20.1 Pseudohypoparathyroidism
0.000 0.950 0.049
E20.0 Idiopathic hypoparathyroidism
0.000 0.950 0.049
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.950 0.049
E45 Retarded development following protein-energy malnutrition
0.000 0.950 0.049
E43 Unspecified severe protein-energy malnutrition
0.000 0.950 0.049
E42 Marasmic kwashiorkor
0.000 0.950 0.049
E41 Nutritional marasmus
0.000 0.950 0.049
E40 Kwashiorkor
0.000 0.950 0.049
E67 Other hyperalimentation
0.000 0.951 0.049
E68 Sequelae of hyperalimentation
0.000 0.951 0.049
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.951 0.049
E07.1 Dyshormogenetic goitre
0.000 0.952 0.048
E07.0 Hypersecretion of calcitonin
0.000 0.952 0.048
E10.4 With neurological complications
0.000 0.952 0.048
E20.9 Hypoparathyroidism, unspecified
0.000 0.952 0.048
E07.8 Other specified disorders of thyroid
0.000 0.953 0.047
E23.6 Other disorders of pituitary gland
0.000 0.953 0.047
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.953 0.047
E23.1 Drug-induced hypopituitarism
0.000 0.953 0.047
E03.9 Hypothyroidism, unspecified
0.000 0.953 0.047
E10.8 With unspecified complications
0.000 0.953 0.047
E06.9 Thyroiditis, unspecified
0.000 0.954 0.046
E06.5 Other chronic thyroiditis
0.000 0.954 0.046
E06.4 Drug-induced thyroiditis
0.000 0.954 0.046
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.954 0.046
E06.1 Subacute thyroiditis
0.000 0.954 0.046
E06.0 Acute thyroiditis
0.000 0.954 0.046
E26.9 Hyperaldosteronism, unspecified
0.000 0.954 0.046
E26.8 Other hyperaldosteronism
0.000 0.954 0.046
E26.1 Secondary hyperaldosteronism
0.000 0.954 0.046
E66.8 Other obesity
0.000 0.954 0.046
E50.9 Vitamin A deficiency, unspecified
0.000 0.955 0.045
E50.8 Other manifestations of vitamin A deficiency
0.000 0.955 0.045
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.955 0.045
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.955 0.045
E50.5 Vitamin A deficiency with night blindness
0.000 0.955 0.045
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.955 0.045
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.955 0.045
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.955 0.045
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.955 0.045
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.955 0.045
E51.9 Thiamine deficiency, unspecified
0.000 0.955 0.045
E51.8 Other manifestations of thiamine deficiency
0.000 0.955 0.045
E51.2 Wernicke's encephalopathy
0.000 0.955 0.045
E51.1 Beriberi
0.000 0.955 0.045
E56.9 Vitamin deficiency, unspecified
0.000 0.955 0.045
E56.8 Deficiency of other vitamins
0.000 0.955 0.045
E56.1 Deficiency of vitamin K
0.000 0.955 0.045
E56.0 Deficiency of vitamin E
0.000 0.955 0.045
E63.9 Nutritional deficiency, unspecified
0.000 0.955 0.045
E63.8 Other specified nutritional deficiencies
0.000 0.955 0.045
E63.1 Imbalance of constituents of food intake
0.000 0.955 0.045
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.955 0.045
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.955 0.045
E64.8 Sequelae of other nutritional deficiencies
0.000 0.955 0.045
E64.3 Sequelae of rickets
0.000 0.955 0.045
E64.2 Sequelae of vitamin C deficiency
0.000 0.955 0.045
E64.1 Sequelae of vitamin A deficiency
0.000 0.955 0.045
E64.0 Sequelae of protein-energy malnutrition
0.000 0.955 0.045
E10.5 With peripheral circulatory complications
0.000 0.956 0.044
E21.3 Hyperparathyroidism, unspecified
0.000 0.956 0.044
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.956 0.044
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.956 0.044
E16.4 Abnormal secretion of gastrin
0.000 0.956 0.044
E16.3 Increased secretion of glucagon
0.000 0.956 0.044
E23.7 Disorder of pituitary gland, unspecified
0.000 0.956 0.044
E46 Unspecified protein-energy malnutrition
0.000 0.957 0.043
E16.1 Other hypoglycaemia
0.000 0.957 0.043
E10.1 With ketoacidosis
0.000 0.958 0.042
E55.0 Rickets, active
0.000 0.958 0.041
E65 Localised adiposity
0.000 0.958 0.041
E07.9 Disorder of thyroid, unspecified
0.000 0.959 0.041
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.040 0.960 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.040 0.960 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.040 0.960 0.000
E26.0 Primary hyperaldosteronism
0.000 0.961 0.039
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.961 0.039
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.039 0.961 0.000
E61.9 Deficiency of nutrient element, unspecified
0.000 0.962 0.038
E61.8 Deficiency of other specified nutrient elements
0.000 0.962 0.038
E61.7 Deficiency of multiple nutrient elements
0.000 0.962 0.038
E61.6 Vanadium deficiency
0.000 0.962 0.038
E61.5 Molybdenum deficiency
0.000 0.962 0.038
E61.4 Chromium deficiency
0.000 0.962 0.038
E61.3 Manganese deficiency
0.000 0.962 0.038
E61.0 Copper deficiency
0.000 0.962 0.038
E34.8 Other specified endocrine disorders
0.000 0.962 0.038
E34.5 Androgen resistance syndrome
0.000 0.962 0.038
E34.4 Constitutional tall stature
0.000 0.962 0.038
E34.3 Short stature, not elsewhere classified
0.000 0.962 0.038
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.962 0.038
E34.1 Other hypersecretion of intestinal hormones
0.000 0.962 0.038
E14.8 With unspecified complications
0.000 0.962 0.038
E14.7 With multiple complications
0.000 0.962 0.038
E14.6 With other specified complications
0.000 0.962 0.038
E14.5 With peripheral circulatory complications
0.000 0.962 0.038
E14.2 Withrenal complications
0.000 0.962 0.038
E14.1 With ketoacidosis
0.000 0.962 0.038
E14.0 With coma
0.000 0.962 0.038
E29.9 Testicular dysfunction, unspecified
0.000 0.962 0.037
E29.8 Other testicular dysfunction
0.000 0.962 0.037
E29.0 Testicular hyperfunction
0.000 0.962 0.037
E23.0 Hypopituitarism
0.000 0.963 0.037
E55.9 Vitamin D deficiency, unspecified
0.000 0.963 0.037
T43.0 Tricyclic and tetracyclic antidepressants
0.036 0.964 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.964 0.036
E66.1 Drug-induced obesity
0.000 0.964 0.036
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.036 0.964 0.000
E44.1 Mild protein-energy malnutrition
0.000 0.964 0.035
E44.0 Moderate protein-energy malnutrition
0.000 0.964 0.035
E67.8 Other specified hyperalimentation
0.000 0.964 0.035
E67.3 Hypervitaminosis D
0.000 0.964 0.035
E67.2 Megavitamin-B6 syndrome
0.000 0.964 0.035
E67.1 Hypercarotenaemia
0.000 0.964 0.035
E67.0 Hypervitaminosis A
0.000 0.964 0.035
E61.1 Iron deficiency
0.000 0.965 0.035
E66.0 Obesity due to excess calories
0.000 0.965 0.035
E06.3 Autoimmune thyroiditis
0.000 0.965 0.034
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.034 0.966 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.034 0.966 0.000
E14.9 Without complications
0.000 0.967 0.033
E61.2 Magnesium deficiency
0.000 0.967 0.033
E14.3 With ophthalmic complications
0.000 0.967 0.032
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.032 0.968 0.000
E34.9 Endocrine disorder, unspecified
0.000 0.968 0.032
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.032 0.968 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.031 0.969 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.030 0.969 0.000
T39.1 4-Aminophenol derivatives
0.030 0.970 0.000
T39.0 Salicylates
0.030 0.970 0.000
E14.4 With neurological complications
0.000 0.970 0.030
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.030 0.970 0.000
T36 Poisoning by systemic antibiotics
0.030 0.970 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.030 0.970 0.000
T43.6 Psychostimulants with abuse potential
0.030 0.970 0.000
T40.4 Other synthetic narcotics
0.030 0.970 0.000
E34.0 Carcinoid syndrome
0.001 0.970 0.029
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.029 0.971 0.000
T39.4 Antirheumatics, not elsewhere classified
0.029 0.971 0.000
T39.2 Pyrazolone derivatives
0.029 0.971 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.029 0.971 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.029 0.971 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.029 0.971 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.029 0.971 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.029 0.971 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.029 0.971 0.000
H40.2 Primary angle-closure glaucoma
0.029 0.971 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.028 0.972 0.000
T43.9 Psychotropic drug, unspecified
0.028 0.972 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.028 0.972 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.028 0.972 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.028 0.972 0.000
T50.8 Diagnostic agents
0.028 0.972 0.000
T40.2 Other opioids
0.027 0.973 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.027 0.973 0.000
T43.2 Other and unspecified antidepressants
0.026 0.974 0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.026 0.974 0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.026 0.974 0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.026 0.974 0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.026 0.974 0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.026 0.974 0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.026 0.974 0.000
T44.1 Other parasympathomimetics [cholinergics]
0.026 0.974 0.000
T44.0 Anticholinesterase agents
0.026 0.974 0.000
T42.1 Iminostilbenes
0.026 0.974 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.025 0.975 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.025 0.975 0.000
T40.8 Lysergide [LSD]
0.025 0.975 0.000
T40.7 Cannabis (derivatives)
0.025 0.975 0.000
T40.5 Cocaine
0.025 0.975 0.000
T40.3 Methadone
0.025 0.975 0.000
T40.1 Heroin
0.025 0.975 0.000
T40.0 Opium
0.025 0.975 0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand
0.024 0.976 0.000
T45.2 Vitamins, not elsewhere classified
0.023 0.976 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.023 0.977 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.023 0.977 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.023 0.977 0.000
T42.3 Barbiturates
0.023 0.977 0.000
T42.2 Succinimides and oxazolidinediones
0.023 0.977 0.000
T42.0 Hydantoin derivatives
0.023 0.977 0.000
T40.6 Other and unspecified narcotics
0.023 0.977 0.000
T50.7 Analeptics and opioid receptor antagonists
0.023 0.977 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.023 0.977 0.000
T50.5 Appetite depressants
0.023 0.977 0.000
T50.4 Drugs affecting uric acid metabolism
0.023 0.977 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.023 0.977 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.023 0.977 0.000
T50.1 Loop [high-ceiling] diuretics
0.023 0.977 0.000
T50.0 Mineralocorticoids and their antagonists
0.023 0.977 0.000
T36.0 Penicillins
0.023 0.977 0.000
T45.1 Antineoplastic and immunosuppressive drugs
0.023 0.977 0.000
T45.5 Anticoagulants
0.022 0.978 0.000
T45.9 Primarily systemic and haematological agent, unspecified
0.022 0.978 0.000
T45.8 Other primarily systemic and haematological agents
0.022 0.978 0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.022 0.978 0.000
T45.6 Fibrinolysis-affecting drugs
0.022 0.978 0.000
T45.4 Iron and its compounds
0.022 0.978 0.000
T45.3 Enzymes, not elsewhere classified
0.022 0.978 0.000
T36.9 Systemic antibiotic, unspecified
0.022 0.978 0.000
T36.8 Other systemic antibiotics
0.022 0.978 0.000
T36.7 Antifungal antibiotics, systemically used
0.022 0.978 0.000
T36.6 Rifamycins
0.022 0.978 0.000
T36.5 Aminoglycosides
0.022 0.978 0.000
T36.4 Tetracyclines
0.022 0.978 0.000
T36.3 Macrolides
0.022 0.978 0.000
T36.2 Chloramphenicol group
0.022 0.978 0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics
0.022 0.978 0.000
E04.1 Non-toxic single thyroid nodule
0.000 0.978 0.021
T37.9 Systemic anti-infective and antiparasitic, unspecified
0.021 0.979 0.000
T37.8 Other specified systemic anti-infectives and antiparasitics
0.021 0.979 0.000
T37.5 Antiviral drugs
0.021 0.979 0.000
T37.4 Anthelminthics
0.021 0.979 0.000
T37.3 Other antiprotozoal drugs
0.021 0.979 0.000
T37.2 Antimalarials and drugs acting on other blood protozoa
0.021 0.979 0.000
T37.1 Antimycobacterial drugs
0.021 0.979 0.000
T37.0 Sulphonamides
0.021 0.979 0.000
T41.5 Therapeutic gases
0.021 0.979 0.000
T41.4 Anaesthetic, unspecified
0.021 0.979 0.000
T41.3 Local anaesthetics
0.021 0.979 0.000
T41.2 Other and unspecified general anaesthetics
0.021 0.979 0.000
T41.1 Intravenous anaesthetics
0.021 0.979 0.000
T41.0 Inhaled anaesthetics
0.021 0.979 0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system
0.021 0.979 0.000
T48.6 Antiasthmatics, not elsewhere classified
0.021 0.979 0.000
T48.5 Anti-common-cold drugs
0.021 0.979 0.000
T48.4 Expectorants
0.021 0.979 0.000
T48.3 Antitussives
0.021 0.979 0.000
T48.2 Other and unspecified agents primarily acting on muscles
0.021 0.979 0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.021 0.979 0.000
T48.0 Oxytocic drugs
0.021 0.979 0.000
T49.9 Topical agent, unspecified
0.021 0.979 0.000
T49.8 Other topical agents
0.021 0.979 0.000
T49.7 Dental drugs, topically applied
0.021 0.979 0.000
T49.6 Otorhinolaryngological drugs and preparations
0.021 0.979 0.000
T49.5 Ophthalmological drugs and preparations
0.021 0.979 0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.021 0.979 0.000
T49.3 Emollients, demulcents and protectants
0.021 0.979 0.000
T49.2 Local astringents and local detergents
0.021 0.979 0.000
T49.1 Antipruritics
0.021 0.979 0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.021 0.979 0.000
T38.9 Other and unspecified hormone antagonists
0.021 0.979 0.000
T38.8 Other and unspecified hormones and their synthetic substitutes
0.021 0.979 0.000
T38.7 Androgens and anabolic congeners
0.021 0.979 0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.021 0.979 0.000
T38.5 Other oestrogens and progestogens
0.021 0.979 0.000
T38.4 Oral contraceptives
0.021 0.979 0.000
T38.2 Antithyroid drugs
0.021 0.979 0.000
T38.1 Thyroid hormones and substitutes
0.021 0.979 0.000
T38.0 Glucocorticoids and synthetic analogues
0.021 0.979 0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.021 0.979 0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.021 0.979 0.000
T47.8 Other agents primarily affecting the gastro-intestinal system
0.021 0.979 0.000
T47.7 Emetics
0.021 0.979 0.000
T47.6 Antidiarrhoeal drugs
0.021 0.979 0.000
T47.5 Digestants
0.021 0.979 0.000
T47.4 Other laxatives
0.021 0.979 0.000
T47.3 Saline and osmotic laxatives
0.021 0.979 0.000
T47.2 Stimulant laxatives
0.021 0.979 0.000
T47.0 Histamine H(2)-receptor antagonists
0.021 0.979 0.000
T47.1 Other antacids and anti-gastric-secretion drugs
0.021 0.979 0.000
T42.4 Benzodiazepines
0.020 0.979 0.000
T45.0 Antiallergic and antiemetic drugs
0.020 0.980 0.000
E29.1 Testicular hypofunction
0.001 0.980 0.019
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.018 0.982 0.000
T46.8 Antivaricose drugs, including sclerosing agents
0.018 0.982 0.000
T46.7 Peripheral vasodilators
0.018 0.982 0.000
T46.5 Other antihypertensive drugs, not elsewhere classified
0.018 0.982 0.000
T46.3 Coronary vasodilators, not elsewhere classified
0.018 0.982 0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.018 0.982 0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.018 0.982 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.018 0.982 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.017 0.982 0.000
T46.1 Calcium-channel blockers
0.017 0.983 0.000
E10.9 Without complications
0.000 0.983 0.017
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.017 0.983 0.000
F31 Bipolar affective disorder
0.016 0.984 0.000
F30-F39 Mood [affective] disorders
0.016 0.984 0.000
F30 Manic episode
0.015 0.985 0.000
F31.9 Bipolar affective disorder, unspecified
0.015 0.985 0.000
F30.0 Hypomania
0.015 0.985 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.014 0.986 0.000
F33 Recurrent depressive disorder
0.014 0.986 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.014 0.986 0.000
F39 Unspecified mood [affective] disorder
0.014 0.986 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.013 0.987 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.013 0.987 0.000
M17.0 Primary gonarthrosis, bilateral
0.000 0.987 0.013
F34 Persistent mood [affective] disorders
0.013 0.987 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.012 0.987 0.000
E11.9 Without complications
0.000 0.988 0.012
F32 Depressive episode
0.012 0.988 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.012 0.988 0.000
F31.8 Other bipolar affective disorders
0.012 0.988 0.000
F31.7 Bipolar affective disorder, currently in remission
0.012 0.988 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.012 0.988 0.000
E66.9 Obesity, unspecified
0.000 0.988 0.012
F38 Other mood [affective] disorders
0.012 0.988 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.012 0.988 0.000
F30.8 Other manic episodes
0.011 0.989 0.000
F30.2 Mania with psychotic symptoms
0.011 0.989 0.000
F30.1 Mania without psychotic symptoms
0.011 0.989 0.000
F30.9 Manic episode, unspecified
0.011 0.989 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.011 0.989 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.011 0.989 0.000
Y57.5 X-ray contrast media
0.011 0.989 0.000
F32.1 Moderate depressive episode
0.011 0.989 0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)
0.011 0.989 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.011 0.989 0.000
F33.8 Other recurrent depressive disorders
0.010 0.990 0.000
F33.4 Recurrent depressive disorder, currently in remission
0.010 0.990 0.000
F33.0 Recurrent depressive disorder, current episode mild
0.010 0.990 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.010 0.990 0.000
F34.1 Dysthymia
0.010 0.990 0.000
Y57 Other and unspecified drugs and medicaments
0.010 0.990 0.000
M72.09 Palmar fascial fibromatosis [Dupuytren]-Site unspec
0.009 0.990 0.000
M72.08 Palmar fascial fibromatosis [Dupuytren]-Other
0.009 0.990 0.000
M72.07 Palmar fascial fibromatosis [Dupuytren]-Ankle/Foot
0.009 0.990 0.000
M72.06 Palmar fascial fibromatosis [Dupuytren]-Lower Leg
0.009 0.990 0.000
M72.05 Palmar fascial fibromatosis [Dupuytren]-Pelvic/Thigh
0.009 0.990 0.000
M72.03 Palmar fascial fibromatosis [Dupuytren]-Forearm
0.009 0.990 0.000
M72.02 Palmar fascial fibromatosis [Dupuytren]-Upper arm
0.009 0.990 0.000
M72.01 Palmar fascial fibromatosis [Dupuytren]-Shldr region
0.009 0.990 0.000
M72.00 Palmar fascial fibromatosis [Dupuytren]-Mult sites
0.009 0.990 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.010 0.990 0.000
F33.9 Recurrent depressive disorder, unspecified
0.009 0.991 0.000
F34.9 Persistent mood [affective] disorder, unspecified
0.009 0.991 0.000
F34.8 Other persistent mood [affective] disorders
0.009 0.991 0.000
F34.0 Cyclothymia
0.009 0.991 0.000
F32.8 Other depressive episodes
0.009 0.991 0.000
F38.8 Other specified mood [affective] disorders
0.009 0.991 0.000
F38.1 Other recurrent mood [affective] disorders
0.009 0.991 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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